The International Criminal Court (ICC), established in 2002, has to-date initiated investigations exclusively in Sub-Saharan Africa. The ICC Prosecutor has opened cases against 16 individuals for alleged crimes in northern Uganda, the Democratic Republic of Congo, the Central African Republic, and the Darfur region of Sudan. In addition, the Prosecutor is investigating postelection violence in Kenya and analyzing situations-a preliminary step toward initiating a full investigation-in Guinea and several other African countries, as well as several countries outside of Africa. Congressional interest in the work of the ICC in Africa has arisen from concern over gross human rights violations on the African continent and beyond. On March 4, 2009, ICC judges issued an arrest warrant for Sudanese President Omar Hassan al- Bashir for war crimes and crimes against humanity. The case against Bashir represents the first attempt by the ICC to pursue a sitting head of state. The prosecution has drawn praise from human rights advocates as a step toward ending impunity for serious human rights abuses in Africa. However, it has also raised concerns that ICC actions could endanger peace processes in Darfur and southern Sudan. Additional fears that the ICC could imperil international humanitarian operations were heightened when the Sudanese government responded to the warrant by expelling international relief agencies. Unlike the four other African countries under ICC investigation, Sudan is not a party to the ICC; instead, the ICC was granted jurisdiction over Darfur through a United Nations Security Council resolution in March 2005. The United States, as a member of the Security Council, may influence the ICC's actions. Obama Administration officials have expressed support for the prosecution of perpetrators of atrocities in Darfur and have suggested that Bashir should face the accusations against him. Legislation before the 111th Congress references the ICC warrant against Bashir and, more broadly, U.S. government support for ICC prosecutions. Four suspects in other ICC investigations are currently in ICC custody, pending trial. Three are alleged leaders of militias in the Democratic Republic of Congo (DRC), and the fourth is a former Congolese rebel leader, transitional vice president, and senator who is accused of overseeing war crimes in neighboring Central African Republic. Additionally, a Darfur rebel leader summoned by ICC judges voluntarily appeared before the Court in May 2009. This report provides background on ICC investigations in Africa and gives an overview of cases currently before the Court. The report also examines issues raised in Africa by the ICC's actions, including the ICC's possible role in deterring future abuses, and the potential impact of international prosecutions on African peace processes. Further background on U.S. policy toward the ICC can be found in CRS Report RL31437, International Criminal Court: Overview and Selected Legal Issues, by Jennifer K. Elsea, and CRS Report R41116, The International Criminal Court (ICC): Jurisdiction, Extradition, and U.S. Policy, by Emily C. Barbour and Matthew C. Weed. [ABSTRACT FROM AUTHOR]