Search

A post hoc analysis of three clinical trials of the drug tenapanor (Ibsrela, Ardelyx) shows that it can improve bowel function and abdominal symptoms in people with irritable bowel syndrome with constipation (IBS-C) within weeks. The drug works by reducing dietary sodium absorption, resulting in softer stool and accelerated intestinal transit. The analysis found that the median time to a response in bowel function was 2 weeks, while the median time to a response in abdominal pain and bloating was 4 and 5 weeks, respectively. The study emphasizes the importance of staying on the medication for a longer period to see improvements in symptoms. [Extracted from the article]

The article focuses on a study published in the Journal of Toxicology and Environmental Health, Part B, which raises concerns about the sugar substitute sucralose (sold as Splenda) and calls for its regulation and discontinuation of consumption due to health risks. The study found that sucralose damages DNA and is linked to leaky gut syndrome, with symptoms such as painful digestion, diarrhea, and bloating.

The article discusses research into digestive enzyme supplements for people that need help digesting complex foods, such as older people, people with pancreatic insufficiency, or people that suffer from gas and bloating.

The article discusses the adverse effects of food intolerances like bloating, cramping and migraines, as well as the suggestion of Doctor Gordon Ko of Sunnybrook Hospital on how to determine if an individual is suffering from food intolerances including the YorkTest FoodScan program.