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Start Over Author "Pan, Wenxu" Publication Type Magazines
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1. Shikonin contributes to intestinal epithelial cell differentiation through PKM2/NRF2-mediated Polyol pathway

Author

Huang, Ling, Tang, Xiufu, Yang, FangYing, Pan, Wenxu, Liang, Xinhua, Xu, Zhaohui, Cao, Meiwan, Zhao, Junhong, Chen, Huan, Huang, Jing, Chen, Jiayu, Geng, Lanlan, Xu, Wanfu, and Gong, Sitang

Abstract

Alteration of polyol pathway is a critical event in serials of disease, including inflammatory bowel disease (IBD). Shikonin, an inhibitor of PKM2, has been reported to exert a wide range of biological and pharmacological properties. However, the function of shikonin-mediated polyol pathway in IBD remained to be addressed.

Published
2021
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