Search

Your search keyword '"Jolly, Sanjit S."' showing total 29 results
Start Over Author "Jolly, Sanjit S." Publication Type Magazines
29 results on '"Jolly, Sanjit S."'

1. Effect of colchicine on perioperative atrial fibrillation and myocardial injury after non-cardiac surgery in patients undergoing major thoracic surgery (COP-AF): an international randomised trial

Author

Conen, David, Ke Wang, Michael, Popova, Ekaterine, Chan, Matthew T V, Landoni, Giovanni, Cata, Juan P, Reimer, Cara, McLean, Sean R, Srinathan, Sadeesh K, Reyes, Juan Carlos Trujillo, Grande, Ascension Martín, Tallada, Anna Gonzalez, Sessler, Daniel I, Fleischmann, Edith, Kabon, Barbara, Voltolini, Luca, Cruz, Patrícia, Maziak, Donna E, Gutiérrez-Soriano, Laura, McIntyre, William F, Tandon, Vikas, Martínez-Téllez, Elisabeth, Guerra-Londono, Juan Jose, DuMerton, Deborah, Wong, Randolph H L, McGuire, Anna L, Kidane, Biniam, Roux, Diego Parise, Shargall, Yaron, Wells, Jennifer R, Ofori, Sandra N, Vincent, Jessica, Xu, Lizhen, Li, Zhuoru, Eikelboom, John W, Jolly, Sanjit S, Healey, Jeff S, Devereaux, P J, Conen, David, Devereaux, PJ, Vincent, Jessica, Wang, Michael Ke, Wells, Jennifer R., Healey, Jeff S., Landoni, Giovanni, McIntyre, William F., Popova, Ekaterine, Sessler, Daniel I., Srinathan, Sadeesh K., Amir, Mohammed, Bangdiwala, Shrikant I., Bossard, Matthias, Chan, Matthew TV, Eikelboom, John W., Fleischmann, Edith, Jolly, Sanjit, Montes, Felix Ramón, Reimer, Cara, Schmartz, Denis, Wang, Chew Yin, Ofori, Sandra N., Blum, Steffen, Alvarez-Garcia, Jesus, Lo Bianco, Giuliana, Traquair, Hugh, Guerrero-Pinedo, Fernando Andres, Oleynick, Christopher, Meyre, Pascal B., Méndez-Zurita, Francisco, Chiarella-Redfern, Helene, Marcucci, Maura, Donati, Francesco, Gonzalez-Osuna, Aranzazu, Minervini, Fabrizio, Moreno Weidmann, Zoraida, Guerra-Ramos, Jose M., Dion, Gabriel, Ramos-Pachón, Anna, Borges, Flavia K., de Sa Boasquevisque, Danielle, Mosconi, Maria Giulia, Amarenco, Pierre, Mitchell, L. Brent, Wyse, George, Cheng, Davy, McAlister, Finlay A., Wells, George A., Baskaran, Geethan, Burns, Andrew T., Gennaccaro, Julia, Howe, Rosemary, Mastrangelo, Louise, Pettit, Shirley, Popovic, Michelle, Shahbaz, Subana, Tosh, Makayla, Zucchetto, Simona J., Heenan, Laura, Lee, Shun Fu, Li, Zhuoru, Xu, Lizhen, Kabon, Barbara, Hoetzenecker, Konrad, Schweiger, Thomas, Reiterer, Christian, Zotti, Oliver, Bsuchner, Paul, Hochreiter, Beatrix, Taschner, Alexander, Adamowitsch, Nikolas, Horvath, Katharina, Hantáková, Nicole, Bidgoli, Javad, Huybrechts, Isabelle, Cappeliez, Serge, Neary, John D., Shargall, Yaron, Tandon, Vikas, Finley, Christian, Agzarian, John, Hanna, Waël, Abdulrahman, Muammar, Lawrence, Kelly, Gregus, Krysten, Quraishi, Faraaz, Wikkerink, Spencer, Wallace, Christine, Prine, Merissa, Gregus, Emily, Hare, Jacqueline, Lombardo, Kristen, Fezia, Behashta, Columbus, Teresa, Rushton, Jacob, DuMerton, Deborah, Reid, Ken, Parlow, Joel, Chung, Wiley, Karizhenskaia, Maria, Malik, Aftab, Tanzola, Rob, Giles, Andrew, McLean, Sean R., McGuire, Anna, Lohser, Jens, Lim, Shirley, Grey, Rebecca, Yee, John, Grant, Kyle, Lee, Alex L., Choi, James J., Dewar, Leith R., Durkin, Christopher, Schisler, Travis, Hecht, Patrick, Hughes, Bevan, Kidane, Biniam, Liu, Richard, Tan, Lawrence, Gowing, Stephen, Buduhan, Gordon, Enns, Stephanie, Poole, Emma, Graham, Kristin, Dubik, Niina, Chin, Alex, Maziak, Donna E., Seely, Andrew JE, Gilbert, Sebastien, Villeneuve, P. James, Sundaresan, Sudhir, Gingrich, Molly, Fazekas, Anna, Bucciero, Kirby, Malthaner, Richard A., Lewis, Deb, Fortin, Dalilah, Qiabi, Mehdi, Nayak, Rahul, Plourde, Madelaine Marie, Haider, Tehmina, Murphy, Rowan, Sellers, Daniel, Donahoe, Laura, Lefebvre, Marco, Lanthier, Luc, Ko, Michael Augustine, Parente, David, Cheung, Victoria, Schieman, Colin, Bessissow, Amal, Wong, Randolph HL, Joynt, Gavin M., Lam, Carmen KM, Lau, Rainbow WH, Wan, Innes YP, Underwood, Malcolm J., Wu, William KK, Wong, Wai Tat, Choi, Gordon YS, Lee, Eva, Hui, Ka Yan, Fung, Beaker, Chan, Chee Sam, Ng, Fung Kei, Thung, Kin Hoi, Gutiérrez-Soriano, Laura, Castañeda, Laura Carmenza, Téllez, Luis Jaime, Ortiz-Ramirez, Lina Marcela, Baiardo-Redaelli, Martina, Belletti, Alessandro, Dieci, Elisa, Monaco, Fabrizio, Muriana, Piergiorgio, Nakhnoukh, Cristina, Novellis, Pierluigi, Turi, Stefano, Viscardi, Stefano, Veronesi, Giulia, Voltolini, Luca, Bongiolatti, Stefano, Salvicchi, Alberto, Gatteschi, Lavinia, Indino, Rossella, Tombelli, Simone, Ravasin, Alice, Salimbene, Ottavia, Rosboch, Giulio Luca, Balzani, Eleonora, Ceraolo, Edoardo, Neitzert, Luca, Brazzi, Luca, Londero, Francesco, Grossi, William, Massullo, Domenico, Fiorelli, Silvia, Margaritora, Stefano, Hashim, Shahrul Amry, Krishnasamy, Sivakumar, See, Woan Shiang, Nawaz, Mohammed Asghar, Bilal, Haris, Trujillo Reyes, Juan Carlos, Martínez-Téllez, Elisabeth, Belda Sanchis, Josep, Planas Canovas, Georgina, Libreros Niño, Alejandra, Parera Ruiz, Ana, Cladellas Gutierrez, Esther, Guarino, Mauro, Urrutia Cuchi, Gerard, Argilaga Nogues, Marta, Rovira Juan, Anna, Medina-Aedo, Melixa, Turró Castillejo, Mª Asunción, Gil Sanchez, Josep Mª, Araúz-Sarmiento, Ibell, Herranz Perez, Gracia, Chavarria Murillo, Stephania, Garcia-Osuna, Alvaro, Rodriguez-Arias, Ainhoa, Berga Garrote, Nuria, Martín Grande, Ascension, Parise Roux, Diego, Gajate Martín, Luis, De Pablo Pajares, Angélica, Candela Toha, Angel Manuel, Moreno Mata, Nicolás, Muñoz Molina, Gema, Caballero Silva, Usue, Cabañero, Alberto, Fra Fernandez, Sara, Cavestany García-Matres, Cristina, Simón, Luisa, Montenegro, Cristina, Pozo, Sergio, Gonzàlez-Tallada, Anna, González Suarez, Susana, Ribas Ball, Montserrat, De Nadal Clanchet, Miriam, Pérez Vélez, Javier, Cruz, Patrícia, Sánchez-Pedrosa, Guillermo, Duque, Patricia, González, Guillermo, Huerta, Luis, Rodríguez, Laura, Garutti, Ignacio, Ruiz-Villa, Laura, Martí-Ejarque, Maria del Mar, Gili-Bueno, Mireia, Maddio Vieyra, Ricardo Matias, Fibla, Juan J., Durán, Núria, de Temple Pla, Marina, Rodríguez-Fuster, Alberto, Bermejo-Martínez, Silvia, Carramiñana, Albert, Opitz, Isabelle, Etienne, Harry, Cata, Juan P., Guerra-Londono, Juan Jose, Rajaram, Ravi, Corrales, German, Vaporciyan, Ara, Mehran, Reza, Sepesi, Boris, Walsh, Garrett, Rice, David, Cukierman, Daniel S., Swisher, Stephen, Marchant, Bryan E., Harris, Lynne C., Cusson, Bruce D., Miller, Scott A., Ayad, Sabry, Araujo, Jorge, Marquez-Roa, Leonardo, Hofstra, Richard L., Wudel, Leonard J., Minear, Steven C., Teixeira, Camila, Pimentel, Mario, Popoff, Andrew M., Marsack, Kelly, Meehan, Sarah, Chen, Tzonghuei H., Essandoh, Michael, and Poppers, Jeremy S.

Abstract

Higher levels of inflammatory biomarkers are associated with an increased risk of perioperative atrial fibrillation and myocardial injury after non-cardiac surgery (MINS). Colchicine is an anti-inflammatory drug that might reduce the incidence of these complications.

Published
2023
Full Text
View/download PDF

3. Colchicine and aspirin in community patients with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial

Author

Eikelboom, John W, Jolly, Sanjit S, Belley-Cote, Emilie P, Whitlock, Richard P, Rangarajan, Sumathy, Xu, Lizhen, Heenan, Laura, Bangdiwala, Shrikant I, Tarhuni, Wadea M, Hassany, Mohamed, Kontsevaya, Anna, Harper, William, Sharma, Sanjib Kumar, Lopez-Jaramillo, Patricio, Dans, Antonio L, Palileo-Villanueva, Lia M, Avezum, Alvaro, Pais, Prem, Xavier, Denis, Felix, Camilo, Yusufali, Afzalhussein, Lopes, Renato D, Berwanger, Otavio, Ali, Zeeshan, Wasserman, Sean, Anand, Sonia S, Bosch, Jackie, Choudhri, Shurjeel, Farkouh, Michael E, Loeb, Mark, and Yusuf, Salim

Abstract

The large number of patients worldwide infected with the SARS-CoV-2 virus has overwhelmed health-care systems globally. The Anti-Coronavirus Therapies (ACT) outpatient trial aimed to evaluate anti-inflammatory therapy with colchicine and antithrombotic therapy with aspirin for prevention of disease progression in community patients with COVID-19.

Published
2022
Full Text
View/download PDF

4. Colchicine and the combination of rivaroxaban and aspirin in patients hospitalised with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial

Author

Eikelboom, John W, Jolly, Sanjit S, Belley-Cote, Emilie P, Whitlock, Richard P, Rangarajan, Sumathy, Xu, Lizhen, Heenan, Laura, Bangdiwala, Shrikant I, Luz Diaz, Maria, Diaz, Rafael, Yusufali, Afzalhussein, Kumar Sharma, Sanjib, Tarhuni, Wadea M, Hassany, Mohamed, Avezum, Alvaro, Harper, William, Wasserman, Sean, Almas, Aysha, Drapkina, Oxana, Felix, Camilo, Lopes, Renato D, Berwanger, Otavio, Lopez-Jaramillo, Patricio, Anand, Sonia S, Bosch, Jackie, Choudhri, Shurjeel, Farkouh, Michael E, Loeb, Mark, and Yusuf, Salim

Abstract

COVID-19 disease is accompanied by a dysregulated immune response and hypercoagulability. The Anti-Coronavirus Therapies (ACT) inpatient trial aimed to evaluate anti-inflammatory therapy with colchicine and antithrombotic therapy with the combination of rivaroxaban and aspirin for prevention of disease progression in patients hospitalised with COVID-19.

Published
2022
Full Text
View/download PDF

5. Effects on Mortality and Major Bleeding of Radial Versus Femoral Artery Access for Coronary Angiography or Percutaneous Coronary Intervention: Meta-Analysis of Individual Patient Data From 7 Multicenter Randomized Clinical Trials

Author

Gargiulo, Giuseppe, Giacoppo, Daniele, Jolly, Sanjit S., Cairns, John, Le May, Michel, Bernat, Ivo, Romagnoli, Enrico, Rao, Sunil V., van Leeuwen, Maarten A.H., Mehta, Shamir R., Bertrand, Olivier F., Wells, George A., Meijers, Thomas A., Siontis, George C.M., Esposito, Giovanni, Windecker, Stephan, Jüni, Peter, and Valgimigli, Marco

Published
2022
Full Text
View/download PDF

6. Complete Revascularization vs Culprit Lesion–Only Percutaneous Coronary Intervention for Angina-Related Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction: Results From the COMPLETE Randomized Clinical Trial

Author

Mehta, Shamir R., Wang, Jia, Wood, David A., Spertus, John A., Cohen, David J., Mehran, Roxana, Storey, Robert F., Steg, Philippe Gabriel, Pinilla-Echeverri, Natalia, Sheth, Tej, Bainey, Kevin R., Bangalore, Sripal, Cantor, Warren J., Faxon, David P., Feldman, Laurent J., Jolly, Sanjit S., Kunadian, Vijay, Lavi, Shahar, Lopez-Sendon, Jose, Madan, Mina, Moreno, Raul, Rao, Sunil V., Rodés-Cabau, Josep, Stankovic, Goran, Bangdiwala, Shrikant I., and Cairns, John A.

Abstract

IMPORTANCE: In patients with multivessel coronary artery disease (CAD) presenting with ST-segment elevation myocardial infarction (STEMI), complete revascularization reduces major cardiovascular events compared with culprit lesion–only percutaneous coronary intervention (PCI). Whether complete revascularization also improves angina-related health status is unknown. OBJECTIVE: To determine whether complete revascularization improves angina status in patients with STEMI and multivessel CAD. DESIGN, SETTING, AND PARTICIPANTS: This secondary analysis of a randomized, multinational, open label trial of patient-reported outcomes took place in 140 primary PCI centers in 31 countries. Patients presenting with STEMI and multivessel CAD were randomized between February 1, 2013, and March 6, 2017. Analysis took place between July 2021 and December 2021. INTERVENTIONS: Following PCI of the culprit lesion, patients with STEMI and multivessel CAD were randomized to receive either complete revascularization with additional PCI of angiographically significant nonculprit lesions or to no further revascularization. MAIN OUTCOMES AND MEASURES: Seattle Angina Questionnaire Angina Frequency (SAQ-AF) score (range, 0 [daily angina] to 100 [no angina]) and the proportion of angina-free individuals by study end. RESULTS: Of 4041 patients, 2016 were randomized to complete revascularization and 2025 to culprit lesion–only PCI. The mean (SD) age of patients was 62 (10.7) years, and 3225 (80%) were male. The mean (SD) SAQ-AF score increased from 87.1 (17.8) points at baseline to 97.1 (9.7) points at a median follow-up of 3 years in the complete revascularization group (score change, 9.9 [95% CI, 9.0-10.8]; P < .001) compared with an increase of 87.2 (18.4) to 96.3 (10.9) points (score change, 8.9 [95% CI, 8.0-9.8]; P < .001) in the culprit lesion–only group (between-group difference, 0.97 points [95% CI, 0.27-1.67]; P = .006). Overall, 1457 patients (87.5%) were free of angina (SAQ-AF score, 100) in the complete revascularization group compared with 1376 patients (84.3%) in the culprit lesion–only group (absolute difference, 3.2% [95% CI, 0.7%-5.7%]; P = .01). This benefit was observed mainly in patients with nonculprit lesion stenosis severity of 80% or more (absolute difference, 4.7%; interaction P = .02). CONCLUSIONS AND RELEVANCE: In patients with STEMI and multivessel CAD, complete revascularization resulted in a slightly greater proportion of patients being angina-free compared with a culprit lesion–only strategy. This modest incremental improvement in health status is in addition to the established benefit of complete revascularization in reducing cardiovascular events.

Published
2022
Full Text
View/download PDF

7. Routine Ultrasonography Guidance for Femoral Vascular Access for Cardiac Procedures: The UNIVERSAL Randomized Clinical Trial

Author

Jolly, Sanjit S., AlRashidi, Sulaiman, d’Entremont, Marc-André, Alansari, Omar, Brochu, Bradley, Heenan, Laura, Skuriat, Elizabeth, Tyrwhitt, Jessica, Raco, Michael, Tsang, Michael, Valettas, Nicholas, Velianou, James L., Sheth, Tej, Sibbald, Matthew, Mehta, Shamir R., Pinilla-Echeverri, Natalia, Schwalm, Jon David, Natarajan, Madhu K., Kelly, Andrew, Akl, Elie, Tawadros, Sarah, Camargo, Mercedes, Faidi, Walaa, Bauer, John, Moxham, Rachel, Nkurunziza, James, Dutra, Gustavo, and Winter, Jose

Abstract

IMPORTANCE: A significant limitation of femoral artery access for cardiac interventions is the increased risk of vascular complications and bleeding compared with radial access. Strategies to make femoral access safer are needed. OBJECTIVE: To determine whether routinely using ultrasonography guidance for femoral arterial access for coronary angiography/intervention reduces bleeding or vascular complications. DESIGN, SETTING, AND PARTICIPANTS: The Routine Ultrasound Guidance for Vascular Access for Cardiac Procedures (UNIVERSAL) randomized clinical trial is a multicenter, prospective, open-label trial of ultrasonography-guided femoral access vs no ultrasonography for coronary angiography or intervention with planned femoral access. Patients were randomized from June 26, 2018, to April 26, 2022. Patients with ST-elevation myocardial infarction were not eligible. INTERVENTIONS: Ultrasonography guidance vs no ultrasonography guidance for femoral arterial access on a background of fluoroscopic landmarking. MAIN OUTCOMES AND MEASURES: The primary composite outcome is the composite of major bleeding based on the Bleeding Academic Research Consortium 2, 3, or 5 criteria or major vascular complications within 30 days. RESULTS: A total of 621 patients were randomized at 2 centers in Canada (mean [SD] age, 71 [10.24] years; 158 [25.4%] female). The primary outcome occurred in 40 of 311 patients (12.9%) in the ultrasonography group vs 50 of 310 patients (16.1%) without ultrasonography (odds ratio, 0.77 [95% CI, 0.49-1.20]; P = .25). The rates of Bleeding Academic Research Consortium 2, 3, or 5 bleeding were 10.0% (31 of 311) vs 10.7% (33 of 310) (odds ratio, 0.93 [95% CI, 0.55-1.56]; P = .78). The rates of major vascular complications were 6.4% (20 of 311) vs 9.4% (29 of 310) (odds ratio, 0.67 [95% CI, 0.37-1.20]; P = .18). Ultrasonography improved first-pass success (277 of 311 [86.6%] vs 222 of 310 [70.0%]; odds ratio, 2.76 [95% CI, 1.85-4.12]; P < .001) and reduced the number of arterial puncture attempts (mean [SD], 1.2 [0.5] vs 1.4 [0.8]; mean difference, −0.26 [95% CI, −0.37 to −0.16]; P < .001) and venipuncture (10 of 311 [3.1%] vs 37 of 310 [11.7%]; odds ratio, 0.24 [95% CI, 0.12-0.50]; P < .001) with similar times to access (mean [SD], 114 [185] vs 129 [206] seconds; mean difference, −15.1 [95% CI, −45.9 to 15.8]; P = .34). All prerandomization prespecified subgroups were consistent with the overall finding. CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, use of ultrasonography for femoral access did not reduce bleeding or vascular complications. However, ultrasonography did reduce the risk of venipuncture and number of attempts. Larger trials may be required to demonstrate additional potential benefits of ultrasonography-guided access. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03537118

Published
2022
Full Text
View/download PDF

8. Transradial Angiography and Intervention in Acute Coronary Syndromes

Author

Akl, Elie, Rashid, Mohammed K., Alshatti, Ahmad, and Jolly, Sanjit S.

Abstract

Considerable evidence supports transradial angiography and intervention in patients with acute coronary syndrome, with an emphasis on decreasing major bleeding and access site vascular complications. Patients undergoing invasive treatment are at greatest risk of bleeding and have the most to gain. The radial advantage has consistently been shown to translate into reduced mortality in pooled data analyses. The benefits of transradial access have been demonstrated across the acute coronary syndrome spectrum and in both sexes. A radial-first strategy should be the default approach and continuous efforts should be made to increase operator expertise of transradial access in these patients.

Published
2020
Full Text
View/download PDF

9. Outcomes Among Clopidogrel, Prasugrel, and Ticagrelor in ST-Elevation Myocardial Infarction Patients Who Underwent Primary Percutaneous Coronary Intervention From the TOTAL Trial

Author

Welsh, Robert C., Sidhu, Robinder S., Cairns, John A., Lavi, Shahar, Kedev, Sasko, Moreno, Raul, Cantor, Warren J., Stankovic, Goran, Meeks, Brandi, Yuan, Fei, Džavík, Vladimír, and Jolly, Sanjit S.

Abstract

Robust comparisons between oral P2Y12 inhibitors (clopidogrel, prasugrel, ticagrelor) in ST-elevation myocardial infarction (STEMI) patients who undergo primary percutaneous coronary intervention are lacking. We sought to evaluate outcomes on the basis of P2Y12 inhibitor therapy in patients from the Thrombectomy With PCI Versus PCI Alone in Patients With STEMI Undergoing Primary PCI (TOTAL) trial.

Published
2019
Full Text
View/download PDF

11. Thrombus Aspiration in ST-Segment–Elevation Myocardial Infarction

Author

Jolly, Sanjit S., James, Stefan, Džavík, Vladimír, Cairns, John A., Mahmoud, Karim D., Zijlstra, Felix, Yusuf, Salim, Olivecrona, Goran K., Renlund, Henrik, Gao, Peggy, Lagerqvist, Bo, Alazzoni, Ashraf, Kedev, Sasko, Stankovic, Goran, Meeks, Brandi, and Frøbert, Ole

Abstract

Supplemental Digital Content is available in the text.

Published
2017
Full Text
View/download PDF

13. Outcomes after thrombus aspiration for ST elevation myocardial infarction: 1-year follow-up of the prospective randomised TOTAL trial

Author

Jolly, Sanjit S, Cairns, John A, Yusuf, Salim, Rokoss, Michael J, Gao, Peggy, Meeks, Brandi, Kedev, Sasko, Stankovic, Goran, Moreno, Raul, Gershlick, Anthony, Chowdhary, Saqib, Lavi, Shahar, Niemela, Kari, Bernat, Ivo, Cantor, Warren J, Cheema, Asim N, Steg, Philippe Gabriel, Welsh, Robert C, Sheth, Tej, Bertrand, Olivier F, Avezum, Alvaro, Bhindi, Ravinay, Natarajan, Madhu K, Horak, David, Leung, Raymond C M, Kassam, Saleem, Rao, Sunil V, El-Omar, Magdi, Mehta, Shamir R, Velianou, James L, Pancholy, Samir, and Džavík, Vladimír

Abstract

Two large trials have reported contradictory results at 1 year after thrombus aspiration in ST elevation myocardial infarction (STEMI). In a 1-year follow-up of the largest randomised trial of thrombus aspiration, we aimed to clarify the longer-term benefits, to help guide clinical practice.

Published
2016
Full Text
View/download PDF

15. Sedation, Analgesia, and Anaesthesia Variability in Laboratory-Based Cardiac Procedures: An International Survey

Author

Lavi, Shahar, Jolly, Sanjit S., Bainbridge, Daniel, Manji, Farah, Randhawa, Varinder, and Lavi, Ronit

Abstract

There is a paucity of data regarding the type of anaesthesia used and the perception toward anaesthesia among cardiologists, anaesthesiologists, and nurses. Our objective was to describe the use of sedation during nonsurgical cardiac procedures.

Published
2014
Full Text
View/download PDF

16. Impact of access to hospitals with catheterization facilities in the second Gulf Registry of Acute Coronary Events (Gulf RACE-2)

Author

AlHabib, Khalid F., Jolly, Sanjit S., Yusuf, Salim, Alsheikh-Ali, Alawi A., Al Suwaidi, Jassim, Hersi, Ahmad, Sulaiman, Kadhim, Al Saif, Shukri, Almahmeed, Wael, Asaad, Nidal, Amin, Haitham, Al-Motarreb, Ahmed, Alfaleh, Hussam, Alnemer, Khalid, and Thalib, Lukman

Abstract

It is currently unclear whether acute coronary syndrome patients who access hospitals with catheterization facilities, with or without an on-site percutaneous coronary intervention (PCI), have better outcomes in real-life clinical practice.

Published
2013
Full Text
View/download PDF

17. Characterization of Operator Learning Curve for Transradial Coronary Interventions

Author

Ball, Warren T., Sharieff, Waseem, Jolly, Sanjit S., Hong, Tony, Kutryk, Michael J.B., Graham, John J., Fam, Neil P., Chisholm, Robert J., and Cheema, Asim N.

Abstract

Transradial percutaneous coronary intervention (TR-PCI) improves clinical outcomes compared to the transfemoral (TF) approach. However, inadequate training and experience has limited widespread adoption by interventional cardiologists.

Published
2011
Full Text
View/download PDF

18. Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre trial

Author

Jolly, Sanjit S, Yusuf, Salim, Cairns, John, Niemelä, Kari, Xavier, Denis, Widimsky, Petr, Budaj, Andrzej, Niemelä, Matti, Valentin, Vicent, Lewis, Basil S, Avezum, Alvaro, Steg, Philippe Gabriel, Rao, Sunil V, Gao, Peggy, Afzal, Rizwan, Joyner, Campbell D, Chrolavicius, Susan, and Mehta, Shamir R

Abstract

Small trials have suggested that radial access for percutaneous coronary intervention (PCI) reduces vascular complications and bleeding compared with femoral access. We aimed to assess whether radial access was superior to femoral access in patients with acute coronary syndromes (ACS) who were undergoing coronary angiography with possible intervention.

Published
2011
Full Text
View/download PDF

19. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial

Author

Mehta, Shamir R, Tanguay, Jean-Francois, Eikelboom, John W, Jolly, Sanjit S, Joyner, Campbell D, Granger, Christopher B, Faxon, David P, Rupprecht, Hans-Jurgen, Budaj, Andrzej, Avezum, Alvaro, Widimsky, Petr, Steg, Philippe Gabriel, Bassand, Jean-Pierre, Montalescot, Gilles, Macaya, Carlos, Di Pasquale, Giuseppe, Niemela, Kari, Ajani, Andrew E, White, Harvey D, Chrolavicius, Susan, Gao, Peggy, Fox, Keith AA, and Yusuf, Salim

Abstract

Clopidogrel and aspirin are the most commonly used antiplatelet therapies for percutaneous coronary intervention (PCI). We assessed the effect of various clopidogrel and aspirin regimens in prevention of major cardiovascular events and stent thrombosis in patients undergoing PCI.

Published
2010
Full Text
View/download PDF

20. Management of the master endurance athlete with stable coronary artery disease

Author

d’Entremont, Marc-André, Couture, Étienne L., Connelly, Kim, Walling, Ann, Jolly, Sanjit S., Valettas, Nicholas, Tsang, Micheal B., Mampuya, Warner, Poirier, Paul, and Huynh, Thao

Abstract

Master endurance athletes are individuals >35 years of age who either train for or participate in competitions. Considering the potential burden of coronary artery disease in this population, clinicians should be aware of the inherent dangers of exercise. A tailored approach with shared decision-making, balancing risks and benefits of exercise, is recommended to ensure safe exercise in these individuals.

Published
2022
Full Text
View/download PDF

22. Association of Thrombus Aspiration With Time and Mortality Among Patients With ST-Segment Elevation Myocardial Infarction: A Post Hoc Analysis of the Randomized TOTAL Trial

Author

Moxham, Rachel, Džavík, Vladimír, Cairns, John, Natarajan, Madhu K., Bainey, Kevin R., Akl, Elie, Tsang, Michael B., Lavi, Shahar, Cantor, Warren J., Madan, Mina, Liu, Yan Yun, and Jolly, Sanjit S.

Abstract

IMPORTANCE: Patients with shorter ischemic times have a greater viable myocardium and may derive greater benefit from thrombus aspiration. OBJECTIVE: To study the association of thrombus aspiration with outcomes among patients presenting with ST-segment elevation myocardial infarction (STEMI) based on time. DESIGN, SETTING, AND PARTICIPANTS: The TOTAL (Thrombectomy With PCI vs PCI Alone in Patients with STEMI) trial was an international randomized clinical trial of 10?732 patients with STEMI undergoing primary percutaneous coronary intervention (PCI) within 12 hours of symptom onset. Patients were recruited between August 5, 2010, and July 25, 2014, and were followed up for 1 year. Data analysis was performed from February 22, 2019, to January 5, 2021. INTERVENTIONS: Thrombus aspiration vs PCI alone. MAIN OUTCOMES AND MEASURES: Post hoc subgroup analyses were performed for total ischemic time and first medical contact (FMC)–to–device time for the primary outcomes (cardiovascular [CV] mortality, myocardial Infarction [MI], cardiogenic shock, and New York Heart Association class IV heart failure) and angiographically determined distal embolization. In addition, a multivariable analysis was performed to assess the association of total ischemic time and FMC-to-device time with CV mortality at 1 year. RESULTS: The study randomized 10?732 patients, and 9986 underwent primary PCI and had time data available (7737 men [77.5%]; mean [SD] age, 61.0 [12.0] years). For the randomized comparison of thrombus aspiration, there was a reduction in angiographic distal embolization with thrombus aspiration that was more pronounced in patients with short ischemic times (<2 hours: odds ratio [OR], 0.23 [95% CI, 0.09-0.62]; 2-6 hours: OR, 0.54 [95% CI, 0.39-0.73]; >6 hours: OR, 0.70 [95% CI, 0.33-1.50]; P?=?.12 for interaction). However, for the primary composite outcome, there was no benefit based on (1) total ischemic time (<2 hours: hazard ratio [HR], 0.77 [95% CI, 0.46-1.28]; 2-6 hours: HR, 1.03 [95% CI, 0.85-1.25]; >6 hours: HR, 0.87 [95% CI, 0.60-1.27]; P?=?.46 for interaction) or (2) FMC-to-device time (<60 minutes: HR, 1.14 [95% CI, 0.66-1.95]; 60-90 minutes: HR, 0.94 [95% CI, 0.67-1.32]; >90-120 minutes: HR, 1.19 [95% CI, 0.85-1.67]; >120 minutes: HR, 0.89 [95% CI, 0.70-1.14]; P?=?.54 for interaction). In a multivariable analysis, both total ischemic time (>2 hours: HR, 1.26 [95% CI, 1.00-1.58) and FMC-to-device time (>120 minutes: HR, 1.45 [95% CI, 1.18-1.79]) were independently associated with CV mortality. CONCLUSIONS AND RELEVANCE: This analysis suggests that thrombus aspiration does not appear to be associated with an improvement in clinical outcomes regardless of ischemic time. In the current STEMI era, both total ischemic time and FMC-to-device times continue to be important factors associated with mortality. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01149044

Published
2021
Full Text
View/download PDF

26. Sealing Intermediate Nonobstructive Coronary Saphenous Vein Graft Lesions With Drug-Eluting Stents as a New Approach to Reducing Cardiac Events

Author

Rodés-Cabau, Josep, Jolly, Sanjit S., Cairns, John, Mansour, Samer, L’Allier, Philippe L., Teefy, Patrick J., Graham, John J., Le May, Michel R., Cantor, Warren J., Wood, David, Balasubramanian, Kumar, DeLarochellière, Robert, and Dzavik, Vlad

Abstract

Supplemental Digital Content is available in the text.

Published
2016
Full Text
View/download PDF

29. Randomized Controlled Trial of Radiation Protection With a Patient Lead Shield and a Novel, Nonlead Surgical Cap for Operators Performing Coronary Angiography or Intervention

Author

Alazzoni, Ashraf, Gordon, Chris L., Syed, Jaffer, Natarajan, Madhu K., Rokoss, Michael, Schwalm, Jon-David, Mehta, Shamir R., Sheth, Tej, Valettas, Nicholas, Velianou, James, Pandie, Shaheen, Al Khdair, Darar, Tsang, Michael, Meeks, Brandi, Colbran, Kiersten, Waller, Ed, Fu Lee, Shun, Marsden, Tamara, and Jolly, Sanjit S.

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results