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A recent study conducted in Gwangju, South Korea, focused on the African Swine Fever Virus (ASFV), which causes a highly lethal disease in domestic pigs and wild boars. The researchers aimed to develop a safe and effective vaccine for ASFV, but faced challenges due to the lack of a suitable cell line for virus propagation. They identified a novel cell line, CAS-01, which showed high permissiveness for ASFV replication and demonstrated stable replication and adaptation over multiple passages. The researchers concluded that CAS-01 cells hold promise for the isolation, replication, and development of live attenuated vaccines against ASFV. [Extracted from the article]

A study conducted by researchers at Chungnam National University in South Korea has identified a novel immune evasion mechanism of the African Swine Fever Virus (ASFV). The virus, which causes African swine fever (ASF), a highly contagious and often fatal disease in pigs, inhibits the type I interferon pathway by targeting STING and 2'3'-cGAMP. The researchers found that ASFV B175L, a protein encoded by the virus, interacts with both cGAMP and STING, interfering with the antiviral signaling response. This discovery could potentially contribute to the development of live-attenuated ASFV vaccines. [Extracted from the article]

2021 DEC 11 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators discuss new findings in Biosensors. According to news reporting out of [...]