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Start Over Author "GROSSMAN, S.J." Publication Type Magazines
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1. Arene oxides and trans-dihydrodiols of quinoline

Author

Agarwal, S.K., Boyd, D.R., Porter, H.P., Jennings, W.B., Grossman, S.J., and Jerina, D.M.

Abstract

Arene oxides and trans-dihydrodiols at the 5,6- and 7,8-positions of quinoline have been synthesized. High stability of both arene oxides allowed identification of the 5,6-oxide as a liver microsomal metabolite of quinoline. Both arene oxides are converted to trans-dihydrodiols by microsamal epoxide hydrolase.

Published
1986
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