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We investigate third-order strongly nonlinear differential equations of the type (Φ(k(t)u″(t)))′=f(t,u(t),u′(t),u″(t)),a.e. on[0,T],\left(\Phi \left(k\left(t){u}^{^{\prime\prime} }\left(t)))^{\prime} =f\left(t,u\left(t),u^{\prime} \left(t),{u}^{^{\prime\prime} }\left(t)),\hspace{1em}\hspace{0.1em}\text{a.e. on}\hspace{0.1em}\hspace{0.33em}\left[0,T], where Φ\Phi is a strictly increasing homeomorphism, and the non-negative function kk may vanish on a set of measure zero. Using the upper and lower solution method, we prove existence results for some boundary value problems associated with the aforementioned equation. Moreover, we also consider second-order integro-differential equations like (Φ(k(t)v′(t)))′=ft,∫0tv(s)ds,v(t),v′(t),a.e. on[0,T],\left(\Phi \left(k\left(t)v^{\prime} \left(t)))^{\prime} =f\left(t,\underset{0}{\overset{t}{\int }}v\left(s){\rm{d}}s,v\left(t),v^{\prime} \left(t)\right),\hspace{1em}\hspace{0.1em}\text{a.e. on}\hspace{0.1em}\hspace{0.33em}\left[0,T], for which we provide existence results for various types of boundary conditions, including periodic, Sturm-Liouville, and Neumann-type conditions.

ABSTRACT Objective: To perform the cross-cultural adaptation of CALCULATE for Brazilian Portuguese. Method: A methodological study conducted from January to December 2021, divided into six stages: translation, synthesis, back-translation, expert committee with the application of the content validity index, pre-testing in 40 adult patients, and submission to the authors. The study took place in the intensive care units of a public tertiary teaching hospital in the interior of the state of São Paulo, Brazil. The original CALCULATE has eight risk assessment items and is stratified with a score of 0-3 (high risk) and 4-8 (very high risk). Results: After expert evaluation, the final content validity was 0.9. They suggested words and phrases that should undergo changes regarding textual equivalences, as well as definitions of acronyms and terminologies. In the pre-test, the items were assessed as suitable for understanding; only one item required additional explanation for adequacy. Conclusion: The cross-cultural adaptation of CALCULATE for Brazilian Portuguese was successfully performed, revealing a good content validity index, confirming the relevance and appropriateness of its items. CALCULATE is suitable for use in intensive care units and research and teaching centers.

Abstract Background Improvement of psychosocial-spiritual well-being in patients with life-threatening or life-limiting illness is desirable. Resilience and mindfulness are considered to be helpful for enhancing psychosocial-spiritual well-being. Mindfulness-based interventions have been shown to promote resilience to stress and enhance well-being. However, in medical patients, evidence for the associations between mindfulness and resilience is lacking. We hypothesize patients with higher levels of psychosocial-spiritual well-being demonstrate greater resilience and mindfulness. Methods 200 patients (mean age = 50.2, SD = 15.5) with serious and or life-limiting illnesses were recruited from the NIH Clinical Center. Patients completed a demographic questionnaire, the NIH-HEALS measure of psychosocial-spiritual well-being, the Connor-Davidson Resilience Scale (CD-RISC-10), and the Mindful Attention Awareness Scale (MAAS). The demographic questionnaire also included a question on current stress level. Results The NIH-HEALS was positively correlated to CD-RISC-10 (rs=0.44, p

O artigo propõe uma explicação para as variações das taxas de homicídios no Brasil nas duas últimas décadas. A partir da comparação de experiências etnográficas vividas no universo faccional de quatro capitais (São Paulo, Porto Alegre, São Luís e Maceió), propomos duas estratégias analíticas: 1) a desagregação de séries quantitativas de taxas de homicídios por perfis de vítimas e 2) a construção de sinopses históricas dos conflitos faccionais locais. Demonstramos como as taxas de homicídio, em perfis sociodemográficos específicos, oscilam a partir das mudanças nos conflitos faccionais locais e puxam as variações das taxas agregadas.

This paper proposes an explanation for the variations in homicide rates in Brazil in the past two decades. Based on the comparison of ethnographic experiences lived in the criminal universe of four capital cities (São Paulo, Porto Alegre, São Luís and Maceió), we propose two analytical strategies: 1) the breakdown of quantitative homicide rate data by victim profile, and 2) the construction of historical synopses of conflicts between factions at the local level. We demonstrate how homicide rates, in specific socio-demographic profiles, oscillate based on changes in conflicts between factions at the local level conflicts, and influence variations in the aggregate rates.

Atletas, o público fisicamente ativo e portadores de doenças crônicas buscam cada vez mais por suplementos alimentares proteicos para aumento de massa muscular. Este estudo tem como objetivo verificar a densidade energética, carboidratos, proteí­nas, sádio e aminoácidos essenciais nos rótulos de produtos de whey protein disponí­veis no mercado brasileiro, qualitativa e quantitativamente. Trata-se de um estudo observacional descritivo. Os valores considerados adequados para cada aminoácido essencial avaliado foram baseados na Instrução Normativa nº 28, de 26 de julho de 2018. Foram analisados 75 rótulos de produtos de whey protein, tanto em lojas fí­sicas quanto virtuais, dos quais todos apresentavam descritos valores de macronutrientes nos rótulos. A partir dos dados coletados no estudo, foi possí­vel quantificar o total de fabricantes e, a partir dos rótulos, a avaliação dos produtos com valores dentro do esperado pela legislação. Os dados obtidos têm relevância para a população no ato da escolha do suplemento nutricional. Os resultados mostram que a comunicação nos rótulos não alcança a recomendação má­nima exigida pela Legislação, a qual è fundamental para análise da qualidade dos produtos disponí­veis, não somente pela população em geral que os consume, mas também pelos profissionais que os indicam.

Introduction: the classification systems with standardized languages are established in a set of structured knowledge, concepts founded in a logical and coherent way, based on their similarities. In this sense, identifying a profile with the populations can cooperate for a better definition and situational understanding for that unit and/or patients. Objectives: to perform cross-mapping between the nursing diagnoses of NANDA-I with the manual nursing records in the post-anesthetic recovery room; and, to propose interventions and outcomes, according to standardized language. Method: exploratory, descriptive and retrospective analysis of the nursing records of 187 patients hospitalized from June to July 2018, in the post-anesthetic recovery room of an oncology hospital. Cross-mapping was carried out in three stages: identification of diagnostic indicators; proposition of interventions and activities; and outcomes indicators. The data were analyzed and described in absolute and relative frequencies. Results: of the 13 NANDA-I domains, five were highlighted; were identified five risk diagnoses and 11 focused on the problem; 100% frequency was observed for the diagnoses of: Aspiration, infection and falling risk; Impaired transfer capacity; Impaired bed mobility; Impaired skin/tissue integrity and impaired comfort. Conclusions: from the 16 nursing diagnoses mapped, were selected 22 interventions and 58 activities; 23 results and 48 outcomes indicators.