21 results on '"Glinghammar, Björn"'
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2. Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
3. Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes
4. Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts
5. Proliferative and Molecular Effects of the Dual PPARα/γ Agonist Tesaglitazar in Rat Adipose Tissues: Relevance for Induction of Fibrosarcoma
6. PPARα regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes
7. The regulatory role of PGC1α‐related coactivator in response to drug‐induced liver injury.
8. A longitudinal assessment of miR-122 and GLDH as biomarkers of drug-induced liver injury in the rat.
9. The peroxisome proliferator-activated receptor α agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes: Correlation with serum ALT levels.
10. Keratin-18 and micro RNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts.
11. A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran.
12. Qualification of new biomarkers for drug-induced liver injury in a human cohort
13. Isoform specific ALT measurement during liver and skeletal muscle damage
14. Toxicity with LXR agonists – Problem solving activities for mechanistic understanding
15. Isoforms of alanine aminotransferases in human tissues and serum—Differential tissue expression using novel antibodies
16. New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus .
17. Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa .
18. Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans.
19. Detection of the mitochondrial and catalytically active alanine aminotransferase in human tissues and plasma.
20. PPARdelta increases expression of the human apolipoprotein A-II gene in human liver cells.
21. Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise.
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