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The glandular odontogenic cyst (GOC) is a rare cystic condition that can exhibit aggressive behavior. A 46-year-old man with a brown complexion presented with an increased volume on the right side of his mandible. Cone-beam tomography revealed a hypodense, multilocular image with well-defined margins, affecting the symphysis and mandibular body, and involving the roots of dental elements from 32 through 46. An incisional biopsy confirmed the diagnosis of GOC. The treatment involved the removal of the lesion through curettage and peripheral osteotomy, with a focus on preserving the affected teeth. However, after 6 years, the lesion recurred, prompting a conservative but similar surgical procedure. Subsequently, after 6 months, a lesion was observed in the lingual region of teeth 44 and 45, leading to another enucleation with peripheral osteotomy in that area. To monitor the patient's condition and address the possibility of recurrence, clinical and imaging follow-up examinations are conducted biannually, as approximately 55% of cases show recurrence following conservative treatment. [ABSTRACT FROM AUTHOR]

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Congenital granular cell epulis is a rare benign soft tissue lesion arising from the alveolar ridge in neonates. A rare case of multiple congenital granular cell epulis is reported, alongside a description of its vascular immunohistochemical profile. A female newborn presented with two exophytic pedunculated red nodules located on the alveolar ridge between the future eruption sites of the incisors and canines of the mandible and maxilla. A conservative surgical excision was performed on the second day of life. Histology revealed proliferation of round granular cells containing an abundant eosinophilic cytoplasm with basophilic nuclei, ranging from round to oval in shape. Numerous blood vessels were also seen. Immunohistochemical analysis of the granular cells revealed positivity for CD68, D2-40, Ki67, VEGF, and FGF and negativity for S100, CD34, and CD105. Immunostaining for CD34, CD105, and D2-40 confirmed the presence of a large number of blood and lymphatic vessels. Although rare, an understanding of this lesion is paramount for correct diagnosis and appropriate treatment. In the present report, the immunohistochemical profile confirmed increased vascularization, proving that these lesions are composed of not only new and preexisting blood vessels, but also lymphatic vessels. [ABSTRACT FROM AUTHOR]

Concerns over fishing impacts on marine populations and ecosystems have intensified the need to improve ocean management. One increasingly popular market-based instrument for ecological stewardship is the use of certification and eco-labeling programs to highlight sustainable fisheries with low environmental impacts. The Marine Stewardship Council (MSC) is the most prominent of these programs. Despite widespread discussions about the rigor of the MSC standards, no comprehensive analysis of the performance of MSC-certified fish stocks has yet been conducted. We compared status and abundance trends of 45 certified stocks with those of 179 uncertified stocks, finding that 74% of certified fisheries were above biomass levels that would produce maximum sustainable yield, compared with only 44% of uncertified fisheries. On average, the biomass of certified stocks increased by 46% over the past 10 years, whereas uncertified fisheries increased by just 9%. As part of the MSC process, fisheries initially go through a confidential pre-assessment process. When certified fisheries are compared with those that decline to pursue full certification after pre-assessment, certified stocks had much lower mean exploitation rates (67% of the rate producing maximum sustainable yield vs. 92% for those declining to pursue certification), allowing for more sustainable harvesting and in many cases biomass rebuilding. From a consumer's point of view this means that MSC-certified seafood is 3-5 times less likely to be subject to harmful fishing than uncertified seafood. Thus, MSC-certification accurately identifies healthy fish stocks and conveys reliable information on stock status to seafood consumers. [ABSTRACT FROM AUTHOR]