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Three new copper(II) and nickel(II) complexes, [Cu3L2(μ2-NO3)2(μ1,1-N3)2] (1), [Cu2L2(μ1,1-N3)2]n (2) and [Ni3L2(MeOH)2(μ2-η1:η1-CH3COO)2(μ2-η2:η0-CH3COO)2] (3), where L = 5-bromo-2-((3-methylaminopropylimino)methyl)phenolate, have been synthesized and characterized. The complexes were characterized by elemental analyses, IR, UV–Vis spectra, molar conductivity, and single crystal X-ray diffraction. X-Ray analysis indicates that the Cu ions in 1 are in square pyramidal and octahedral coordination, and the Cu ions in 2 and the Ni ions in 3 are in octahedral coordination. The molecules of the complexes are linked through hydrogen bonds and π···π interactions. The complexes were assayed for antibacterial activities against three Gram-positive bacterial strains (Bacillus subtilis, Staphylococcus aureus, and Streptococcus faecalis) and three Gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae) by the MTT method. [ABSTRACT FROM AUTHOR]

A centipede like thiocyanate-bridged multi-nuclear copper(I/II) complex, [Cu2L(CH3OH)(NCS)3]n, derived from 2-(((2-(dimethylamino)ethyl)imino)methyl)-5-fluorophenol (HL), was prepared and characterized by elemental analysis, IR and UV–vis spectra, as well as single crystal X-ray diffraction. The Cu1 ion in the +2 oxidation state is coordinated by the tridentate Schiff base ligand in a square pyramidal geometry, with the other two sites occupied by one N atom of the thiocyanate ligand and one methanol O atom. The Cu2 ion in the +1 oxidation state is coordinated by one N and three S atoms from four thiocyanate ligands, forming a tetrahedral geometry. The CuI ions are linked by thiocyanate ligands to form a one-dimensional chain with [CuI2(μ1,3,3-NCS)2] as the repeat unit. The [CuIIL(CH3OH)] moieties are linked to the chain through thiocyanate ligands. The complex has remarkable inhibitory activity on Jack bean urease with an IC50 value of 1.3 μmol L–1. [ABSTRACT FROM AUTHOR]