Back to Search
Start Over
A centipede like thiocyanate-bridged muti-nuclear copper(I/II) complex derived from 2-(((2-(dimethylamino)ethyl)imino)methyl)-5-fluorophenol with urease inhibitory activity.
- Source :
-
Journal of Coordination Chemistry . Mar2022, Vol. 75 Issue 5/6, p720-728. 9p. - Publication Year :
- 2022
-
Abstract
- A centipede like thiocyanate-bridged multi-nuclear copper(I/II) complex, [Cu2L(CH3OH)(NCS)3]n, derived from 2-(((2-(dimethylamino)ethyl)imino)methyl)-5-fluorophenol (HL), was prepared and characterized by elemental analysis, IR and UV–vis spectra, as well as single crystal X-ray diffraction. The Cu1 ion in the +2 oxidation state is coordinated by the tridentate Schiff base ligand in a square pyramidal geometry, with the other two sites occupied by one N atom of the thiocyanate ligand and one methanol O atom. The Cu2 ion in the +1 oxidation state is coordinated by one N and three S atoms from four thiocyanate ligands, forming a tetrahedral geometry. The CuI ions are linked by thiocyanate ligands to form a one-dimensional chain with [CuI2(μ1,3,3-NCS)2] as the repeat unit. The [CuIIL(CH3OH)] moieties are linked to the chain through thiocyanate ligands. The complex has remarkable inhibitory activity on Jack bean urease with an IC50 value of 1.3 μmol L–1. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00958972
- Volume :
- 75
- Issue :
- 5/6
- Database :
- Academic Search Index
- Journal :
- Journal of Coordination Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 157772115
- Full Text :
- https://doi.org/10.1080/00958972.2022.2062232