Author: "Zhong, Z." / Publication Type: Academic Journals / Publisher: sage publications inc. / Topic: apoptosis - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Zhong, Z." Topic apoptosis Publication Type Academic Journals Publisher sage publications inc.

Author: ZHONG, Z., QULIAN, G., YUAN, Z., WANGYUAN, Z., and ZHIHUA, S.
Subjects: *ANESTHESIA, *ANESTHETICS, *PHARMACODYNAMICS, *RAT physiology, *APOPTOSIS, *NEUROTOXICOLOGY
Abstract: The article focuses on a study which investigated the possible neurotoxicity of multiple doses of intrathecal ropivacaine in rats. Study authors injected ropivacaine in the rats via an implanted intrathecal catheter at 90-minute intervals. They evaluated apoptosis in the spinal cord using in situ TUNEL assay. They concluded that ropivacaine can induce neurotoxicity and apoptosis in a dose-dependent manner.
Published: 2009

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