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1. Blood pressure outcomes of medication adherence interventions: systematic review and meta-analysis.

Author

Conn, Vicki, Ruppar, Todd, and Chase, Jo-Ana

Subjects
ANALYSIS of variance, BEHAVIOR modification, CINAHL database, DRUGS, ERIC (Information retrieval system), HYPERTENSION, ANTIHYPERTENSIVE agents, MEDICAL databases, INFORMATION storage & retrieval systems, PSYCHOLOGY information storage & retrieval systems, MEDLINE, META-analysis, ONLINE information services, PATIENT compliance, REGRESSION analysis, RESEARCH funding, SYSTEMATIC reviews, EFFECT sizes (Statistics), TREATMENT effectiveness, RESEARCH bias, PHARMACODYNAMICS
Abstract

The article discusses a study on the overall mean impact of adherence interventions on blood pressure outcomes among subjects with hypertension. Study highlights include ancestry searches on eligible studies and review papers, summary measure and method of analyses, and a table that outlines characteristics of primary studies included in blood pressure meta-analyses.

Published
2016
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2. Congenital heart defects and maternal fever: systematic review and meta-analysis.

Author

Shi, Q Y, Zhang, J B, Mi, Y Q, Song, Y, Ma, J, and Zhang, Y L

Subjects
HEART ventricle diseases, ANALYSIS of variance, CHI-squared test, CONFIDENCE intervals, CONGENITAL heart disease, FEVER, INFORMATION storage & retrieval systems, MEDICAL databases, MEDICAL information storage & retrieval systems, MATERNAL health services, MEDLINE, META-analysis, ONLINE information services, FIRST trimester of pregnancy, RESEARCH funding, SYSTEMATIC reviews, DATA analysis software, ODDS ratio
Abstract

OBJECTIVE:To systematically review and meta-analyze the relation between maternal fever in the first trimester and congenital heart defect (CHD) in offspring.STUDY DESIGN:We searched PubMed (1977-2012), Embase (1974-2012) and the Cochrane Library (2012) databases to identify relevant articles. Random effects model were performed, with the conduction of subgroup analysis.RESULT:Meta-analysis yielded a pooled odds ratio of 1.53 (95% confidence interval=1.36 to 1.73) for the magnitude of the relation between maternal fever in the first trimester and CHD in offspring. As to subgroup analysis, it is associated with ventricular septal defects (VSDs) and right obstructive defects.CONCLUSION:Our analysis suggests that maternal fever in the first trimester is the risk factor of congenital heart diseases in offspring. Through the subgroup analysis, we find that exposure to maternal fever is the risk factor of VSD and right obstructive defects. [ABSTRACT FROM AUTHOR]

Published
2014
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