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Objective To study the influencing factors of myasthenic crisis in non-thymoma myasthenia gravis (MG) patients during perioperative period. Methods We retrospectively analyzed a total of 387 non-thymoma MG patients who underwent extended thymoma resection in the Department of Thoracic Surgery of Beijing Hospital from February 2011 to December 2021, recorded ASA score, Osserman classification, preoperative course, pyridostigmine dosage, operation method, operation time, and intraoperative blood loss, then analyzed the factors associated with postoperative myasthenic crisis by univariate and multivariate logistic regression. Results Osserman classification IIB + III + IV (P P = 0.013), pyridostigmine dosage greater than 240 (P P = 0.001) are independent risk factors for myasthenic crisis. Conclusion Patients with poor Osserman classification, history of myasthenic crisis before surgery, larger preoperative dosage of pyridostigmine, and higher ASA scores should be highly alert to the occurrence of postoperative myasthenic crisis.

In this work, a new structure is used to enhance the nonlinear effect in the cavity, which improves the performance of the 1.3[Formula: see text][Formula: see text]m broadband swept source. The swept source adopts a semiconductor optical amplifier (SOA), a circulator, a coupler, and a tunable filter. In the structure, the light passes through the nonlinear medium (SOA) twice in two opposite directions, which excites the nonlinear effect and increases the performance of the swept source. The tunable filter is based on a polygon rotating mirror and gratings. Traditionally, multiple SOAs are adopted to improve the sweep range and the optical power, which increases the cost and complexity of the swept source. The method proposed in this paper can improve the spectral range and optical power of the swept sources without additional accessories. For the short-cavity swept source, the power increases from 6[Formula: see text]mW to 7.7[Formula: see text]mW, and the sweep range increases from 98[Formula: see text]nm to 120[Formula: see text]nm. The broadband swept sources could have wide applications in biomedical imaging, sensor system, measurement and so on.

To study the influencing factors of myasthenic crisis in patients with myasthenia gravis during perioperative period.A total of 564 myasthenia gravis (MG) patients who underwent standard expanded resection of thymoma/thymoma in the Department of Thoracic Surgery of Beijing Hospital from January 2011 to March 2022 were retrospectively included in the study. Clinical indicators such as gender, age, thymoma, American Society of Anesthesiologists (ASA) score, operation time, intraoperative blood loss, and some others were recorded.Osserman-stages IIB + III + IV (odds ratio [OR] 16.091, 95% confidence interval [CI] 5.170-50.076, p value 0.001), the dosage of pyridostigmine bromide more than 240 mg (OR 6.462, 95% CI 3.110-13.427, p value 0.001), ASA score 2 and 3 (OR 3.203, 95% CI 1.461-7.020, p value = 0.004), low diffusion lung capacity for carbon monoxide (DLCO%) (OR 0.981, 95% CI 0.963-1.000 p value = 0.049), and blood loss greater than 1000 ml (OR 16.590, 95% CI 1.911-144.011, p value = 0.011) were independent risk factors for myasthenic crisis.Patients with poor Osserman stages, higher preoperative dosage of pyridostigmine bromide, higher ASA score, poor pulmonary function (low DLCO%), and more intraoperative bleeding should be highly vigilant for the occurrence of postoperative myasthenic crisis.

BACKGROUND: Retrospective research partly characterizes the link between antibiotic use and rheumatoid arthritis (RA) development. This prospective cohort study may help reassess the association. RESEARCH DESIGN AND METHODS: We included 133,125 participants from the Nurses’ Health Study (NHS) and NHS II databases. Three groups were established: nonuse, short-term use (1–14 days), and middle-to long-term use (≥15 days) to explore the link. Cox regression model was chosen to evaluate the hazard ratios (HRs) for RA. RESULTS: Short-term antibiotic use was not associated with the subsequent risk of RA (adjusted HR = 0.88, 95% Confidence Interval [CI] 0.38–1.38) compared to the no antibiotic use group in the multivariable adjusted model. The age-stratified model showed no sufficient evidence of increased risk in participants with middle-to long-term antibiotic use (HR = 1.32, 95% CI 0.89–1.98). The effect further attenuated to null after controlling for confounding factors (adjusted HR = 1.06, 95% CI 0.42–1.71). CONCLUSIONS: We found no evidence of an association between antibiotic use and RA risk. Our findings may reduce potential concerns about increased RA risk among antibiotic users.

Automatic speech recognition (ASR) that relies on audio input suffers from significant degradation in noisy conditions and is particularly vulnerable to speech interference. However, video recordings of speech capture both visual and audio signals, providing a potent source of information for training speech models. Audiovisual speech recognition (AVSR) systems enhance the robustness of ASR by incorporating visual information from lip movements and associated sound production in addition to the auditory input. There are many audiovisual speech recognition models and systems for speech transcription, but most of them have been tested based in a single experimental setting and with a limited dataset. However, a good model should be applicable to any scenario. Our main contributions are: (i) Reproducing the three best-performing audiovisual speech recognition models in the current AVSR research area using the most famous audiovisual databases, LSR2 (Lip Reading Sentences 2) LSR3 (Lip Reading Sentences 3), and comparing and analyzing their performances under various noise conditions. (ii) Based on our experimental and research experiences, we analyzed the problems currently encountered in the AVSR domain, which are summarized as the feature-extraction problem and the domain-generalization problem. (iii) According to the experimental results, the Moco (momentum contrast) + word2vec (word to vector) model has the best AVSR effect on the LRS datasets regardless of whether there is noise or not. Additionally, the model also produced the best experimental results in the experiments of audio recognition and video recognition. Our research lays the foundation for further improving the performance of AVSR models.

Crosslinked polyacrylamide microspheres are widely used as in-depth flooding agents in petroleum development due to their unique properties of thickening, salt-resistance, high-temperature resistance, low cost, etc. To solve the problem of their injections in heterogeneous reservoirs, polyacrylamide nanospheres were synthesized. However, mechanisms of polymer nanospheres in enhanced oil recovery were not investigated comprehensively. In this study, we synthesized polymer nanospheres with different size distributions and studied their mechanisms in enhancing the oil recovery. First, the effects of polyacrylamide nanospheres in enhanced oil recovery of heterogeneous sand-packed tubes was explored by sand-packed tube oil displacement experiments. Second, the rheological properties of polyacrylamide nanosphere dispersion were explored using a rheometer. Third, through the visual microchannel experiment, the mechanism of polymer nanosphere emulsion on the removal of the residual oil film was explored. Finally, through the crude oil removal experiment, it was found that polymer nanospheres with a particle size of about 54 nm can cooperate with surfactants to accelerate the removal of oil droplets.

The 48-V diesel mild-hybrid electric vehicle equipped with an electrically heated catalyst is a cost-effective solution to reduce tailpipe emissions, while its supervisory control design is more challenging, due to cross-coupled energy and thermal subsystems. This article presents a distributed control design for the energy and thermal management system, aiming to optimize fuel economy and reduce catalyst warm-up time, by cooperation between electrical heating and engine load upshift. A control-oriented model of HEV and catalyst is developed, which captures the dynamics of the battery state of charge and catalyst temperature. The energy and thermal management problem is cast as a hybrid optimal control problem, to minimize entire trip fuel consumption under different switching (warm-up) times. An off-line solution method is designed to exploit the tradeoff between fuel and warm-up time based upon hybrid minimum principle and a nested shooting algorithm. For online implementation, a distributed supervisory control is proposed, which covers both cold-start and normal operations, and is compatible with the equivalent consumption minimization strategy. Both off-line and online methods are validated in simulation, using two driving cycles and five warm-up speeds.

Background Proton pump inhibitors (PPIs) have a significant impact on the gut microbiome, which in turn, might increase the risk of rheumatoid arthritis (RA). Aim To evaluate regular use of PPIs and risk of RA. Methods This is a prospective analysis of the US nurses who reported PPI use data, and were free of RA from the Nurses' Health Study (NHS 2002-2014) and NHS II (2003-2015). The exposure was regular use of PPI in the past 2 years, which was repeatedly evaluated in biennial surveys. RA was confirmed by the 1987 or 2010 American College of Rheumatology criteria. We estimated the hazard ratios (HRs) and confidence interval (CIs) with time-dependent Cox regression adjusting for potential confounders. Results We documented 421 cases of RA over 1 753 879 person-years of follow-up. Regular PPI users had a 44% higher risk of RA as compared with non-regular users (adjusted HR = 1.44; 95%CI, 1.10-1.89). The risk of RA increased with the total duration of PPI use (P-trend = 0.008). Compared with non-regular users, the adjusted HRs were 1.22 (95%CI, 0.93-1.62) for women with >0 to 4 years' use and 1.73 (95% CI, 1.14 to 2.61) for >4 years' use. Conclusions Regular use of PPI was associated with increased risk of RA in women, with a higher risk observed in individuals with a longer duration of PPI use. Due to the observational study design, large prospective trials are still required to confirm our finding.

This study investigated the effects of convective drying(CD) and freeze drying(FD) on bioactive and volatile components in jujube. No significant difference in total phenolic, total flavonoids and antioxidant capacity among CD60, CD70, CD80 and FD samples (

With the gradual depletion of fossil energy sources and the improvement in environmental protection attention, efficient use of energy and reduction in carbon emissions have become urgent issues. The integrated electricity and heating energy system (IEHS) is a significant solution to reduce the proportion of fossil fuel and carbon emissions. In this paper, a stochastic optimization model of the IEHS considering the uncertainty of wind power (WP) output and carbon capture power plants (CCPs) is proposed. The WP output in the IEHS is represented by stochastic scenarios, and the scenarios are reduced by fast scenario reduction to obtain typical scenarios. Then, the conventional thermal power plants are modified with CCPs, and the CCPs are equipped with flue gas bypass systems and solution storage to form the integrated and flexible operation mode of CCPs. Furthermore, based on the different load demand responses (DRs) in the IEHS, the optimization model of the IEHS with a CCP is constructed. Finally, the results show that with the proposed optimization model and shunt-type CCP, the integrated operation approach allows for a better reduction in carbon capture costs and carbon emissions.

In this study, YN/VD connected balance transformer-based hybrid power quality compensator (HPQC) is proposed for harmonic suppression and reactive power compensation in electrified railways. The HPQC is composed of a balance transformer in YN/VD connection, a controllable three-phase voltage source inverter (VSI), as well as fully-tuned passive power filters (PPFs). It is able to integrate the active compensation device with the main transformer, without using auxiliary step-down transformer. This circuit configuration enables one to adopt VSI with low power rating, so that merits such as easy for system integration and low operation losses can be achieved. In this paper, the equivalent circuit model and the corresponding mathematical model of the HPQC in the harmonic domain are established to reveal its mechanism on harmonic suppression. And then, the working principle and control strategy of such a new topology are elaborated in detail. Finally, simulation and experimental results are provided to verify the feasibility and effectiveness of the above-mentioned structure and control strategy.

This study investigated the effects of exogenous salicylic acid (SA) treatment (0, control; 3 mmol L

Nonalcoholic fatty liver disease (NAFLD) is a chronic inflammatory disease in which nucleotide-binding domain of leucine-rich repeat protein 3 (NLRP3) inflammasome plays an important role. The present research was aimed to explore the protective function of ADAR1, an RNA editing enzyme, against inflammatory damages in high-fat diet (HFD)-induced NAFLD through inhibiting NLRP3 inflammasome and subsequent inflammation. A total of 30 patients with NAFLD were investigated, and ADAR1 mRNA expression in peripheral blood monocytes surveyed. The in vivo study used lentivirus to explore the function of ADAR1 overexpression in the HFD-induced mouse model of NAFLD. The in vitro study used lentivirus and siRNA to explore the function of ADAR1 on the NLRP3 inflammasome activation in THP-1 cells. Results shown that the ADAR1 expression was upregulated in NAFLD patients in comparison to healthy controls. In vivo, the upregulation of ADAR1 impaired NLRP3 inflammasome activation and alleviated liver disease in HFD mice in comparison to the control group. Moreover, ADAR1 overexpression attenuated NLRP3 inflammasome in lipopolysaccharide (LPS)+ palmitic acid (PA)-induced THP-1 cells, while ADAR1 knockdown increased the NLRP3 inflammasome activation. Furthermore, we speculated that c-Jun may participate in ADAR1's inhibition of NLRP3 inflammasome. Our results suggested that ADAR1 is a potential treatment target for NAFLD via regulating the activation of NLRP3 inflammasome.

The combined cooling and power (CCP) microgrid plays an important role in achieving the goal of dual carbon, while the uncertainty of renewable energy (RE) output and the equipment operation mode bring challenges to the operation optimization. To address this problem, a day-ahead interval optimization model based on interval measurement of CCP microgrid is proposed. First, a large number of scenarios of RE output are generated using Latin hypercube sampling. And the scenarios are reduced by the fast backward reduction method (FBRM). The reduced scenarios are combined with the extreme value theorem to obtain the RE output interval range. Then, the demand response (DR) models of electrical load and cooling load are established to achieve peak-cutting and valley-filling. And the optimization model of ice storage air conditioning (ISAC) with different connection modes is established. Furthermore, the day-ahead interval optimization model is constructed of the CCP microgrid. Finally, the results of the day-ahead optimization model for ISAC under different operation modes are analyzed. The simulation results show the accuracy and effectiveness of the proposed model. The interval radius of the proposed method is reduced by 29.408% and 57.409% compared to the traditional interval method and the original scenario interval method, respectively. And the upper limit of the interval is reduced by 519.9923¥, 1987.6423¥, respectively. In the optimization with the participation of DR and ISAC, the operation cost can be reduced. The economic and stable operation of the CCP microgrid can be realized.

In order to increase the utilization rate of the regenerative braking energy (RBE), reduce the operation cost, and improve the power quality of traction power supply system (TPSS) in high-speed railway, a supercapacitor (SC)-based energy storage system (SCESS) integrated railway static power conditioner (RPC) is presented in this article. In this scheme, the SC is connected onto the dc link of the RPC via a bidirectional dc–dc converter. A hierarchical control strategy, with an energy management layer and a converter control layer, is presented. Four operation modes and transition conditions of SCESS-RPC are elaborated in detail in the energy management layer. To obtain rapid and stable control performance, in the converter control layer, a passivity-based control (PBC)-based nonlinear controller is designed for the RPC, and an optimal control strategy based on the linear quadratic regulator with integral action (LQRI) is adopted for the bidirectional dc–dc converter. By means of simulations and experiments, the feasibility of the proposed topology and control strategy are verified.

Objectives. The aim of this study was to investigate the effects of compound C on an in vivo mouse model of high-fat diet- (HFD-) induced obesity and hepatosteatosis. Methods. C57BL/6 mice were fed with a standard diet (n = 5) for 16 weeks and then injected saline once a day for 4 weeks as the normal chow group. Mice (n = 10) were fed with HFD for 16 weeks to induce obesity and hepatosteatosis and then divided into two groups: HFD + vehicle group injected with the vehicle solution (saline) and HFD + compound C group injected with compound C in saline (5 mg/kg i.p., once a day) for 4 weeks. Liver histology was observed. The expression levels of genes related to lipid metabolism and proinflammation in liver tissue were examined. NLRP3 inflammasome expression in liver tissue was detected by the western blot assay. HepG2 cells were pretreated with compound C and/or AICAR for 1 h and then treated with palmitic acid (PA) for 3 h. The cells were collected, and mRNA levels were determined. Results. There was a significant reduction in body-weight gain and daily food intake in the HFD + compound C group compared with the HFD + vehicle group (p<0.05). The glucose tolerance test (GTT) and insulin tolerance test (ITT) showed that compound C alleviated insulin resistance. Histology analysis showed a significant reduction of hepatic steatosis by compound C. Compound C also significantly decreased fatty acid synthesis genes, while increased fatty acid oxidation genes. Furthermore, compound C significantly reduced the expression of proinflammatory markers and NLRP3 inflammasome (p<0.05). Compound C enhanced mRNA levels of SOD1, SOD2, catalase, GPx1, and GPx4 and reduced the p-AMPK/AMPK ratio, which were stimulated by palmitic acid (PA). The effect was enhanced by AICAR. Conclusion. Our data suggest that compound C is a potent NAFLD suppressor and an attractive therapeutic target for hepatic steatosis and related metabolic disorders.

In this study, magnetic potential balance based active power filter integrated with distribution transformer (DT-APF) is proposed for harmonic reduction in distribution systems. Instead of using a step-down transformer for voltage matching, the active power filter is connected to the taps from the secondary windings of the distribution transformer. The filtering system's integration, operating efficiency as well as reliability are significantly enhanced. The topology of the proposed DT-APF is introduced; the compensation principle, mathematical model as well as the corresponding detection method are described in detail. A non-linear controller based on passivity-based control (PBC) that ensures global asymptotic stability is proposed to obtain an excellent compensation performance. To verify the feasibility and effectiveness of the presented DT-APF and PBC in harmonic suppression, results from MATLAB simulations and experiments of a down-scaled prototype system at laboratory are demonstrated.

To investigate the physiological and molecular properties relating to cell wall carbohydrate metabolism in fruit, the ultrastructure and polysaccharides compositions of the cell wall, as well as the fruit quality and activities of enzymes relating to fruit softening, were studied for three Hami melon varieties (‘Xizhoumi 17’, ‘Jinhuami 25’, and ‘Chougua’) representing three different storability levels. The results showed that ‘Chougua’ maintained a higher firmness on day 18, with the lowest decay incidence (0%). ‘Chougua’ showed a better storage quality and intact cell wall structure. The molecular weight and monosaccharide composition of cell wall polysaccharides for Hami melons underwent great changes during storage, and the degradation of pectin polysaccharides was obvious, involving the depolymerization of macromolecular polymers accompanied by the production of new macromolecular polymers and composition changes in pectin monosaccharides (glucose, galactose, and arabinose) during the softening process of the Hami melons. Polygalacturonase, pectin methylesterase, xyloglucan endo-transglycosylase/hydrolase, α-arabinofuranosidase, β-galactosidase, and cellulase were associated with fruit softening at different stages of storage. There were similar softening mechanisms in the three Hami melons. This study will provide reference for further study on the fruit softening mechanisms of Hami melons.

Due to the poor damping characteristics of the high voltage direct current (HVDC) grid, the fault current will rise sharply when a short-circuit fault appears on the DC side of the HVDC system. State-of-the-art of fault current isolation techniques is a combination of a superconducting fault current limiter (SFCL) with a high voltage DC circuit breaker (DCCB), which is one of the most economical and effective candidates to isolate the fault current. Based on the analysis of resistive-type SFCL and DCCB modeling, a fault isolation strategy based on the cooperation of a resistive-type SFCL and a DCCB is proposed in the HVDC system. The simulation results show that the proposed scheme can provide a positive significance to suppress the DC fault current, and the HVDC system’s robustness can be enhanced as well.

This paper proposes a stochastic economic dispatch strategy considering uncertainties of source and load based on difference regional energy resources. A improved autoregressive model is used to fit output and forecast error data of wind, photovoltaic, and load output for reproducing the asymptotic distribution and diurnal variation. The improved model generates a large number of deterministic scenarios to display the uncertainty and intermittency. Considering uncertainties of source and load based on difference regional energy resources, the quantile scenario reduction method is proposed to obtain different scenarios for ensuring the stochasticity of renewable energy and load. The quantile regression principle in statistics is used to set weights for different quantile scenarios. The proposed multi-scenario stochastic dispatching problem is converted into a MILP model for solving. Some conventional generators of the standard IEEE 39-bus system are connected with renewable power sources for study purpose. Actual data of a regional grid of China is analyzed. The simulation results of the model and strategy are summarized, analyzed and compared in this study. The simulation results show that the cost is reduced by 1.78% and 1.692% compared with the deterministic case and the traditional method. The proposed method could meet its different dispatch requirements and provide a theoretical basis for the generation of dispatching plans.

Winter jujube inevitably suffers from rapid oxidation after harvest, leading to quality deterioration. Temperature plays an important role in the ripening and senescence of fruit. This study aimed to investigate the effect of different temperatures on the quality parameters, antioxidant enzyme activities, and antioxidant enzyme-related gene expressions of winter jujube. Jujube fruit were stored at room temperature (RT: 25 °C) and low temperature (LT: 0 °C) for 35 days, respectively. Compared with RT, LT maintained higher firmness and lower respiratory rate, inhibited the increase of weight loss, decay rate, total soluble solids (TSS) and reddening rate, delayed the decrease of titratable acid (TA) and ascorbic acid (AsA) content. LT-stored jujube fruit also showed higher antioxidant enzyme activities and related gene expression (Mn-SOD, APX, and GR, except CAT). We observed a significant correlation between fruit quality parameters and antioxidant enzymes, suggesting that fruit senescence is closely related to antioxidant ability. In short, LT delayed the ripening rate by inducing a series of physiological and molecular reactions, thereby improving antioxidant levels and storage quality.

Dilated cardiomyopathy (DCM) is a relatively frequent myocardial disease that may lead to heart failure, syncope, and sudden cardiac death. Genetic factors play important roles in the etiology of the disease. To date, at least 50 genes have been identified in patients with DCM, among them, only three mutations have been reported in Synemin (SYNM) gene. In this study, we investigate a Chinese family of three generations with four patients with DCM. Employing whole-exome sequencing (WES) and bioinformatics strategies, a novel heterozygous missense mutation p.(Trp538Arg) of SYNM was identified and cosegregated with the affected family members. The missense mutation locates in the C-terminal domain of SYNM and leads to a substitution of tryptophan by arginine and may cause the structure change of synemin protein. In conclusion, we employed WES to detect the mutations of DCM patients and identified a novel likely pathogenic mutation in SYNM gene. Our study not only expands the spectrum of SYNM mutations, it further confirms that mutations in SYMN may underlie nonfamilial DCM, and offers genetic testing information to additional DCM patients.

In this paper, a modified floor field model is proposed to study dynamics of counter flow in a corridor involving various types of members, i.e., normal pedestrians, pedestrians on crutches, seniors with sticks, pedestrians in manual wheelchairs and blind pedestrians. Multi-speed characteristics, occupation difference and typical behaviors (i.e., overtaking, helping and avoidance behaviors) are simulated in our model. Through simulations in bidirectional flow, typical phenomena (namely lane formation and congestion) are created. The negative effect of the proportion of individuals with disabilities on movement efficiency of heterogeneous counter flow is reproduced. Results suggest that appropriate overtaking willingness has a positive influence on pedestrian counter flow. Helping behavior can induce pedestrian counter flow more orderly, and improve crowd movement efficiency. The proposed model is helpful to enrich modeling approaches for individuals with disabilities, and is beneficial to heterogeneous crowd management.

Ice-temperature storage is a new refrigeration method with temperatures ranging from sub-zero to the freezing point of the product being stored. However, few reports have evaluated the effects of ice-temperature (IT) storage on the cell wall metabolism and reactive oxygen metabolism of Xinjiang-grown Diaogan apricots. In this study, to determine the effects of ice-temperature storage on cell wall metabolism and reactive oxygen metabolism in Diaogan apricots, apricots were stored at −1.5 °C to−2.0 °C (ice temperature, IT), 0 °C–1 °C (low temperature), and 10 °C (control) for 70 d with sampling and evaluation every 10 d. Compared to storage at low temperature and 10 °C, IT storage (1) better maintained the firmness, ascorbic acid content, pectin content, and cellulose content of the fruit; (2) suppressed the activities of polygalacturonase and cellulase; (3) inhibited the rate of weight loss, respiration rate, ethylene production, plasma membrane permeability, and malondialdehyde accumulation; and (4) improved the activities of peroxidase, catalase, superoxide dismutase, and ascorbate peroxidase, thereby inhibiting the accumulation of hydrogen peroxide and superoxide anion during storage. Overall, the results show that IT storage is an effective way to improve the storage quality and antioxidant capacity of Diaogan apricots.

Hydrogel sensor has been widely researched for their flexibility and elasticity; however, its poor mechanical, anti-dry and anti-freezing properties hinder its application in wearable devices seriously. Herein, a flexible, ultra-tough, excellent self-recoverable, anti-dry and anti-freezing ionic EG/MoS2-PAAM-Fe3+ organohydrogel was prepared by adding ethylene glycol to the MoS2-PAAM-Fe3+ hydrogel using solvent exchange method. And due to the pyramid microstructures at the bottom, the “crocodile skin” gel sensor exhibited good pressure sensitivity (S = 0.06 kPa−1) and fast electrical response to monitoring human movements. The MoS2-based organohydrogel with comprehensive properties showed promising application potentials in the new generation of electronic materials and devices used at low temperatures.

Designing and adjusting materials with reasonable microscopic morphology is the key to improving electrochemical performance and assembling hybrid supercapacitors with excellent performance. In this work, firstly, a hydrothermal method is used to grow the NiCo-MOF (NCM) on nickel foam, then NCM is used as the precursor, and the solution containing MXene and Ni2+ and Co2+ are used as the electrolyte to prepare the MXene-Ni-Co@NiCo-MOF/NF (M-NC@NCM/NF) nanosheets through electrodeposition. Since the metal cations will be redistributed between the MXene layers, the nanosheets obtained by electrodeposition in the electrolyte added with MXene exhibit a unique hexagonal nanosheet morphology. This unique form can enhance the electrochemical performance, the capacity retention rate can be maintained at 75.3% after 5000 cycles, and the specific capacity can reach 855.0 C g−1 (2137.5 F g−1) at 1 A g−1.