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1. Early Release Science of the exoplanet WASP-39b with JWST NIRSpec PRISM

Author: Rustamkulov, Z., Sing, D. K., Mukherjee, S., May, E. M., Kirk, J., Schlawin, E., Line, M. R., Piaulet, C., Carter, A. L., Batalha, N. E., Goyal, J. M., López-Morales, M., Lothringer, J. D., MacDonald, R. J., Moran, S. E., Stevenson, K. B., Wakeford, H. R., Espinoza, N., Bean, J. L., Batalha, N. M., Benneke, B., Berta-Thompson, Z. K., Crossfield, I. J. M., Gao, P., Kreidberg, L., Powell, D. K., Cubillos, P. E., Gibson, N. P., Leconte, J., Molaverdikhani, K., Nikolov, N. K., Parmentier, V., Roy, P., Taylor, J., Turner, J. D., Wheatley, P. J., Aggarwal, K., Ahrer, E., Alam, M. K., Alderson, L., Allen, N. H., Banerjee, A., Barat, S., Barrado, D., Barstow, J. K., Bell, T. J., Blecic, J., Brande, J., Casewell, S., Changeat, Q., Chubb, K. L., Crouzet, N., Daylan, T., Decin, L., Désert, J., Mikal-Evans, T., Feinstein, A. D., Flagg, L., Fortney, J. J., Harrington, J., Heng, K., Hong, Y., Hu, R., Iro, N., Kataria, T., Kempton, E. M.-R., Krick, J., Lendl, M., Lillo-Box, J., Louca, A., Lustig-Yaeger, J., Mancini, L., Mansfield, M., Mayne, N. J., Miguel, Y., Morello, G., Ohno, K., Palle, E., Petit Dit De La Roche, D. J. M., Rackham, B. V., Radica, M., Ramos-Rosado, L., Redfield, S., Rogers, L. K., Shkolnik, E. L., Southworth, J., Teske, J., Tremblin, P., Tucker, G. S., Venot, O., Waalkes, W. C., Welbanks, L., Zhang, X., Zieba, S., University of St Andrews. School of Physics and Astronomy, Rustamkulov, Z. [0000-0003-4408-0463], Sing, D. K. [0000-0001-6050-7645], Line, M. R. [0000-0001-6247-8323], Piaulet, C. [0000-0002-2875-917X], Goyal, J. M. [0000-0002-8515-7204], López-Morales, M. [0000-0003-3204-8183], Lothringer, J. D. [0000-0003-3667-8633], Stevenson, K. B. [0000-0002-7352-7941], Wakeford, H. R. [0000-0003-4328-3867], Benneke, B. [0000-0001-5578-1498], Powell, D. K. [0000-0002-4250-0957], Gibson, N. P. [0000-0002-9308-2353], Molaverdikhani, K. [0000-0002-0502-0428], Nikolov, N. K. [0000-0002-6500-3574], Taylor, J. [0000-0003-4844-9838], Wheatley, P. J. [0000-0003-1452-2240], Aggarwal, K. [0000-0002-7004-8670], Ahrer, E. [0000-0003-0973-8426], Alderson, L. [0000-0001-8703-7751], Allen, N. H. [0000-0002-0832-710X], Banerjee, A. [0000-0002-9124-6537], Barrado, D. [0000-0002-5971-9242], Barstow, J. K. [0000-0003-3726-5419], Crouzet, N. [0000-0001-7866-8738], Daylan, T. [0000-0002-6939-9211], Decin, L. [0000-0002-5342-8612], Mikal-Evans, T. [0000-0001-5442-1300], Feinstein, A. D. [0000-0002-9464-8101], Harrington, J. [0000-0002-8955-8531], Hu, R. [0000-0003-2215-8485], Kempton, E. M.-R. [0000-0002-1337-9051], Lillo-Box, J. [0000-0003-3742-1987], Mancini, L. [0000-0002-9428-8732], Mansfield, M. [0000-0003-4241-7413], Mayne, N. J. [0000-0001-6707-4563], Morello, G. [0000-0002-4262-5661], Palle, E. [0000-0003-0987-1593], Petit dit de la Roche, D. J. M. [0000-0002-8963-3810], Redfield, S. [0000-0003-3786-3486], Southworth, J. [0000-0002-3807-3198], Tremblin, P. [0000-0001-6172-3403], Zhang, X. [0000-0002-8706-6963], Apollo - University of Cambridge Repository, Johns Hopkins University (JHU), University of California [Santa Cruz] (UC Santa Cruz), University of California (UC), Johns Hopkins University Applied Physics Laboratory [Laurel, MD] (APL), Imperial College London, Steward Observatory, University of Arizona, ASU School of Earth and Space Exploration (SESE), Arizona State University [Tempe] (ASU), Department of Physics [Montréal], McGill University = Université McGill [Montréal, Canada], NASA Ames Research Center (ARC), National Institute of Science Education and Research (NISER), Harvard-Smithsonian Center for Astrophysics (CfA), Harvard University-Smithsonian Institution, Utah Valley University (UVU), Department of Astronomy, University of Michigan, Carl Sagan Institute, Cornell University [New York], Lunar and Planetary Laboratory [Tucson] (LPL), H. H. Wills Physics Laboratory [Bristol], University of Bristol [Bristol], Space Telescope Science Institute (STSci), Department of Astronomy and Astrophysics [Chicago], University of Chicago, Department of Astrophysical and Planetary Sciences [Boulder], University of Colorado [Boulder], Department of Physics and Astronomy [Lawrence Kansas], University of Kansas [Lawrence] (KU), Earth and Planets Laboratory [Washington], Carnegie Institution for Science, Max Planck Institute for Astronomy (MPIA), INAF/Osservatorio Astronomico di Torino, Turin, Italy, Trinity College Dublin, Laboratoire d'Astrophysique de Bordeaux [Pessac] (LAB), Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), University Observatory Munich, Ludwig-Maximillians University Munich, Ludwig Maximilian University [Munich] (LMU), Observatoire de la Côte d'Azur (OCA), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), University of Oxford, University of Warwick [Coventry], Indian Institute of Technology Indore (IITI), Observatories [Carnegie Institution], The Open University [Milton Keynes] (OU), Astronomical Institute Anton Pannekoek (AI PANNEKOEK), University of Amsterdam [Amsterdam] (UvA), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Bay Area Environmental Research Institute (BAER), New York University [Abu Dhabi], NYU System (NYU), University of Leicester, European Space Agency (Baltimore) Space Telescope Science Institute (ESA), University of St Andrews [Scotland], Leiden Observatory [Leiden], Universiteit Leiden, Department of Physics, Princeton University (DPPU), Princeton University, Université Catholique de Louvain = Catholic University of Louvain (UCL), Max Planck Institute for Radio Astronomy, Department of Astronomy and Astrophysics [UCSC Santa Cruz], University of California (UC)-University of California (UC), Florida Space Institute [Orlando] (FSI), University of Central Florida [Orlando] (UCF), California Institute of Technology (CALTECH), Institut de recherches Arctiques Jean Malaurie (IRAM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay, Maison de la Simulation (MDLS), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire Interuniversitaire des Systèmes Atmosphériques (LISA (UMR_7583)), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), National Aeronautics and Space Administration, NASA, Entomological Society of America, ESA, Space Telescope Science Institute, STScI, Heising-Simons Foundation, HSF, Canadian Space Agency, CSA, (JWST-ERS-01366, NAS 5-03127), Rustamkulov, Z [0000-0003-4408-0463], Sing, DK [0000-0001-6050-7645], Line, MR [0000-0001-6247-8323], Piaulet, C [0000-0002-2875-917X], Goyal, JM [0000-0002-8515-7204], López-Morales, M [0000-0003-3204-8183], Lothringer, JD [0000-0003-3667-8633], Stevenson, KB [0000-0002-7352-7941], Wakeford, HR [0000-0003-4328-3867], Benneke, B [0000-0001-5578-1498], Powell, DK [0000-0002-4250-0957], Gibson, NP [0000-0002-9308-2353], Molaverdikhani, K [0000-0002-0502-0428], Nikolov, NK [0000-0002-6500-3574], Taylor, J [0000-0003-4844-9838], Wheatley, PJ [0000-0003-1452-2240], Aggarwal, K [0000-0002-7004-8670], Ahrer, E [0000-0003-0973-8426], Alderson, L [0000-0001-8703-7751], Allen, NH [0000-0002-0832-710X], Banerjee, A [0000-0002-9124-6537], Barrado, D [0000-0002-5971-9242], Barstow, JK [0000-0003-3726-5419], Crouzet, N [0000-0001-7866-8738], Daylan, T [0000-0002-6939-9211], Decin, L [0000-0002-5342-8612], Mikal-Evans, T [0000-0001-5442-1300], Feinstein, AD [0000-0002-9464-8101], Harrington, J [0000-0002-8955-8531], Hu, R [0000-0003-2215-8485], Kempton, EM-R [0000-0002-1337-9051], Lillo-Box, J [0000-0003-3742-1987], Mancini, L [0000-0002-9428-8732], Mansfield, M [0000-0003-4241-7413], Mayne, NJ [0000-0001-6707-4563], Morello, G [0000-0002-4262-5661], Palle, E [0000-0003-0987-1593], Petit Dit de la Roche, DJM [0000-0002-8963-3810], Redfield, S [0000-0003-3786-3486], Southworth, J [0000-0002-3807-3198], Tremblin, P [0000-0001-6172-3403], and Zhang, X [0000-0002-8706-6963]
Subjects: Earth and Planetary Astrophysics (astro-ph.EP), 141, MCC, Multidisciplinary, Settore FIS/05, 134, [SDV]Life Sciences [q-bio], 639/33/445/862, article, FOS: Physical sciences, 639/33/445/824, DAS, 639/33/34/862, 5109 Space Sciences, 140, QC Physics, Astrophysics - Solar and Stellar Astrophysics, QB Astronomy, Astrophysics - Instrumentation and Methods for Astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM), 51 Physical Sciences, Solar and Stellar Astrophysics (astro-ph.SR), QC, Astrophysics - Earth and Planetary Astrophysics, QB
Abstract: Transmission spectroscopy of exoplanets has revealed signatures of water vapor, aerosols, and alkali metals in a few dozen exoplanet atmospheres. However, these previous inferences with the Hubble and Spitzer Space Telescopes were hindered by the observations' relatively narrow wavelength range and spectral resolving power, which precluded the unambiguous identification of other chemical species$-$in particular the primary carbon-bearing molecules. Here we report a broad-wavelength 0.5-5.5 $\mu$m atmospheric transmission spectrum of WASP-39 b, a 1200 K, roughly Saturn-mass, Jupiter-radius exoplanet, measured with JWST NIRSpec's PRISM mode as part of the JWST Transiting Exoplanet Community Early Release Science Team program. We robustly detect multiple chemical species at high significance, including Na (19$\sigma$), H$_2$O (33$\sigma$), CO$_2$ (28$\sigma$), and CO (7$\sigma$). The non-detection of CH$_4$, combined with a strong CO$_2$ feature, favours atmospheric models with a super-solar atmospheric metallicity. An unanticipated absorption feature at 4$\mu$m is best explained by SO$_2$ (2.7$\sigma$), which could be a tracer of atmospheric photochemistry. These observations demonstrate JWST's sensitivity to a rich diversity of exoplanet compositions and chemical processes., Comment: 41 pages, 4 main figures, 10 extended data figures, 4 tables. Under review in Nature
Published: 2023

2. Correlation between Current Histopathological Grading and Anatomical Location of Mucoepidermoid Carcinoma of Salivary Glands

Author: Ahamed, S, Alam, M. M, and Gain, S. K
Subjects: General Medicine
Abstract: Introduction: Mucoepidermoid carcinoma (MEC) is a kind of salivary cancer with a wide range of biologic activity. Mucoepidermoid tumors are the only kind of cancer where histologic grading and clinical behavior features are linked. Given the relative rarity of this disease, while being the most prevalent of the salivary gland malignancies, this is a common problem in the MEC literature. The aim of the study was to observe the correlation of MEC histopathological grading and anatomical location. Methods: This observational descriptive cross-sectional multi-center study was conducted at the Department of Oral and Maxillofacial Surgery, Dhaka Dental College Hospital, Dhaka, Department of Otolaryngology &Head Neck Surgery, Dhaka Medical College Hospital, Dhaka, and Department of Otolaryngology-Head Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh The study duration was 1.5 years, from July 2011 to December 2012. A total of 20 patients attending the study centers with diagnosed case of mucoepidermoid carcinoma of salivary glands was selected for the study following inclusion and exclusion criteria. Result: 40% of the participants were from the age group of 31-40 years, while another 30% were under the age of 21 years. 70% of the participants were female. Histological grading of the participants revealed 9 low grade, 8 intermediate grade, and 4 high-grade MEC tumor cases. High-grade tumor MEC had an association with increasing age and male gender. The swelling was a common clinical feature among all the participants, whereas ulceration was observed in 75% of high-grade tumor patients. Parotid gland was the most common location at 45%, followed by 30% tumors occurring at the palate. Among the 9 parotid gland carcinomas, 55.6% were from MEC intermediate grade, 33.3% from low grade and the remaining 11.1% from MEC high grade by histological grading. Among the 6 carcinomas of the palate, 50% were low grade, 33.3% were intermediate grade, ..........
Published: 2022

3. StEER-EERI: 2023 Mw 7.8 Kahramanmaras, Türkiye earthquake sequence joint Preliminary Virtual Reconnaissance Report (PVRR)

Author: Dilsiz, A, Gunay, S, Mosalam, K, Miranda, E, Arteta, C, Sezen, H, Fischer, E, Hakhamaneshi, M, Hassan, W, ALhawamdeh, B, Andrus, S, Archbold, J, Arslanturkoglu, S, Bektas, N, Ceferino, L, Cohen, J, Duran, B, Erazo, K, Faraone, G, Feinstein, T, Gautam, R, Gupta, A, Haj Ismail, S, Jana, A, Javadinasab Hormozabad, S, Kasalanati, A, Kenawy, M, Khalil, Z, Liou, I, Marinkovic, M, Martin, A, Merino, Y, Mivehchi, M, Moya, L, Pájaro Miranda, C, Quintero, N, Rivera, J, Romão, X, Camila Lopez Ruiz, M, Sorosh, S, Vargas, L, Velani, P, Wibowo, H, Xu, S, Yilmaz, T, Alam, M, Holtzer, G, Kijewski-Correa, T, Robertson, I, Roueche, D, and Safiey, A
Abstract: An Mw 7.8 earthquake occurred at a depth of 17.9 km and with epicenter coordinates 37.174°N 37.032°E near the city of Nurdağı in the Gaziantep province of Türkiye at about 4:17 AM local time on February 6, 2023. As a result of this sequence of earthquakes and aftershocks, around 28,500 buildings partially or completely collapsed, while another 66,000 buildings were severely damaged in Türkiye. In Syria, more than 22,000 buildings were affected by the earthquakes, with 2,850 partially/completely collapsed or severely damaged. As of March 8, the total official death toll due to these earthquakes was reported to be 45,968 confirmed deaths in Türkiye and 7,259 in Syria. In Türkiye alone, more than 100,000 people were reported as injured. The province of Hatay in Türkiye was severely impacted by this sequence of ground shaking, including an Mw 6.4 earthquake that occurred on February 20, two weeks after the main event. Around half of the buildings in the affected regions of Türkiye were constructed before 2000, i.e., before modern principles of earthquake design were implemented in the Turkish Seismic Code. Fragility functions developed for the building stock in the area showed that collapse under large shaking was possible for these relatively older buildings. However, several collapses of buildings constructed after 2000 were also observed. The performance of infrastructures was generally acceptable, with most bridges, roads, and tunnels remaining operational and no significant issues with the power grid and water supply infrastructure. In terms of good performance, the 12 seismically isolated hospitals in the earthquake-impacted region were operational after the earthquakes and, more importantly, allowed these healthcare facilities to serve their emergency response functions in the aftermath of the extraordinary destruction. Their operational performance greatly contrasted with the observed collapses of some hospitals that were not seismically isolated. This project encompasses the joint products of the StEER and EERI LFE program's response to this event: Preliminary Virtual Reconnaissance Report (PVRR).
Published: 2023

4. Safety and Effectiveness of Platelet Rich Plasma versus Hyaluronic Acid Injection in Pain Management of Hip Osteoarthritis

Author: Arefin M. S, Alam M. M, Haque M. A, Islam S. A, Rahman A. U, and Akhtaruzzaman A. K. M
Abstract: Background: Platelet rich plasma therapy is a simple, low cost and minimally invasive method that provides a natural concentrate of autologous blood growth factors that can be used to enhance tissue regeneration (1). Recent evidences have shown that Platelet Rich Plasma Therapy can be helpful as an osteoarthritis (OA) therapeutic tool by intra-articular injection (2). Hyaluronic acid (HA) is widely used therapy for relief of OA pain and stiffness by intra-articular injection. In addition, there is a sufficient evidence for being significant disease modifying effects. Objectives: The aim of the study was to compare the clinical efficacy of Platelet Rich Plasma with that of hyaluronic acid viscous supplementation. Methods: This study included forty patients with hip osteoarthritis. These patients were selected from the Out Patient Department (OPD) of Dhaka Pain Management Center (DPMC) and Ava Pain & Intervention Center (APIC), Dhaka, Bangladesh during the period from January 2020 to December 2020. Patients were randomly divided into two groups. The first group consisted of 20 patients treated by using intra-articular injection of 2 ml autologous Platelet Rich Plasma Therapy. The second group consisted of 20 patients they were treated by using intra-articular injections of low molecular weight (hyaluronic acid [HA]) (32mg/2mL) of HA (HA group). All patients received 3 injections with one week interval (3) For Follow up: The subjective clinical outcome were measured at baseline, 1, 3, 6 and 12 months after the last treatment dose using the Visual Analog Scale (VAS) (5). Results: The Platelet rich plasma and Hyaluronic Acid groups showed an improvement, with significant difference between the two groups. However after 6 months follow up there was significant improvement in Platelet Rich Plasma Therapy group than HA group (P
Published: 2022

5. Fabrication and Characterization of Graphene-Barium Titanate-Graphene layered capacitors by spin coating at low processing temperatures

Author: Habib, M. S., Farhad, S. F. U., Tanvir, N. I., Alam, M. S., Bitu, M. N. A., Islam, M. S., Islam, S., Khatun, N., and Hossain, M. S
Subjects: Condensed Matter - Materials Science, Materials Science (cond-mat.mtrl-sci), FOS: Physical sciences, Physics - Applied Physics, Applied Physics (physics.app-ph)
Abstract: Barium titanate, BaTiO3 (BT), materials have been synthesized by two different routes: one ball-mill-derived (BMD) nanopowder and another precursor-derived (PCD) BT synthesis method were used separately to fabricate BT thin films on stainless steel (SS) and quartz substrates by spin coating. Then thin films from both synthesis routes were characterized by Ultraviolet-Visible-Near Infrared (UV-Vis-NIR) Spectroscopy, Field-Emission Scanning Electron Microscopy (FE-SEM), X-ray Diffractometry (XRD), Raman Spectroscopy, and Four-point collinear probe; all carried out at room temperature. Our studies revealed that the PCD synthesis process did not produce the BT phase even under the 900^0C air-annealing condition. In contrast, a homogeneous BT thin film has been formed from the BMD-BT nanopowder. The optical band gap of BMD-BT thin films was found in the 3.10 - 3.28 eV range. Finally, a Graphene-Barium Titanate-Graphene (G-BT-G) structure was fabricated on a SS substrate by spin coating at processing temperatures below 100^0C and characterized by two different pieces of equipment: a Potentiostat/Galvanostat (PG-STAT) and a Precision Impedance Analyzer (PIA). The G-BT-G structure exhibited a capacitance of 8 nF and 7.15 nF, a highest dielectric constant of 800 and 790, and a low dielectric loss of 4.5 and 5, investigated by PG-STAT and PIA equipment, respectively., Comment: 25 pages, 11 Figures
Published: 2023
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6. Quantum Enhanced Greedy Solver for Optimization Problems

Author: Dupont, Maxime, Evert, Bram, Hodson, Mark J., Sundar, Bhuvanesh, Jeffrey, Stephen, Yamaguchi, Yuki, Feng, Dennis, Maciejewski, Filip B., Hadfield, Stuart, Alam, M. Sohaib, Wang, Zhihui, Grabbe, Shon, Lott, P. Aaron, Rieffel, Eleanor G., Venturelli, Davide, and Reagor, Matthew J.
Subjects: Quantum Physics, FOS: Physical sciences, Quantum Physics (quant-ph)
Abstract: Combinatorial optimization is a broadly attractive area for potential quantum advantage, but no quantum algorithm has yet made the leap. Noise in quantum hardware remains a challenge, and more sophisticated quantum-classical algorithms are required to bolster performance guarantees. Here, we introduce an iterative quantum heuristic optimization algorithm with an average worst-case performance, in the presence of depolarizing quantum noise, equivalent to that of a classical greedy algorithm. We implement this algorithm on a programmable superconducting quantum system using up to 72 qubits for solving paradigmatic Sherrington-Kirkpatrick Ising spin glass problems. The quantum-classical algorithm systematically outperforms its classical counterpart, signaling a quantum enhancement with respect to its guaranteed output quality. Moreover, we observe an absolute performance comparable with the guarantees for a state-of-the-art semi-definite programming method. Classical simulations of the algorithm illustrate that a key challenge to reaching quantum advantage remains improving the quantum device characteristics., Comment: 9 pages, 5 figures (+ 9 pages, 7 figures)
Published: 2023
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7. Acoustic Wave Propagation through a Random Dispersion of Solid Particles in a Viscous Fluid

Author: Alam, M. Mahbub
Abstract: This thesis is divided into four chapters. The first chapter briefly reviews existing approaches used in studying effective properties of a composite, and sets the scene for the work to follow. Chapter 2 is devoted to the study of a single-sphere scattering. The analytical approximations for scattering coefficients of a solid elastic sphere in a visco-acoustic medium for arbitrary partial wave orders are derived for both incident compressional and shear wave modes in the long-compressional wavelength limit, while imposing no restriction on the shear wavelength. The analytical results, within the validity domain of the solutions, are found to agree with numerical results obtained from the matrix inversion of boundary equations. The work in chapter 3 is concerned with the determination of effective dynamic properties. Used is a core-shell effective medium model to obtain analytical expressions for the effective bulk modulus and mass density for a random dispersion of solid spheres in a viscous fluid by incorporating the viscous nature of the host fluid into the model through wave mode coupling. By employing the CPA, the effective bulk modulus is obtained from the monopole mode and the effective density from the dipole mode. The bulk modulus is found to be quasi-static, whereas the effective density, due to the inclusion of shear-mediated contribution, is found to be dynamic. Chapter 4 is devoted to the study of effective density with spheroids. Extended is a hydrodynamic model by Ament from spherical to spheroidal particles in order to bring out the particle shape dependency on the effective dynamic density. Analytical expressions for the effective density for both prolate and oblate spheroids are obtained and demonstrated to significantly differ from the spherical case.
Published: 2023
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8. StEER 2022 Mw 6.1 Duzce, Turkey Earthquake Preliminary Virtual Reconnaissance Report (PVRR)

Author: Sezen, H, Can Altunisik, A, Emin Arslan, M, Caglar, N, Demir, A, Bektas, N, Dilsiz, A, Gunay, S, Khalil, Z, Marinkovic, M, Safiey, A, Alam, M, Kijewski-Correa, T, and Mosalam, K
Abstract: An earthquake occurred in Duzce, Turkey on Nov. 23, 2022 with magnitude of 6.1 and a depth of 10.0 km. The region has been struck by several destructive earthquakes in the past decades. The vast majority of the buildings in the region affected by the earthquake, including government and school buildings, have been either retrofitted or rebuilt after the Aug.17, 1999 Mw 7.6 Kocaeli and Nov. 12, 1999 Mw 7.2 Duzce earthquakes. No structural damage and nonstructural damage were reported in these buildings during this event. This low level of damage shows the effectiveness of retrofit measures and recent strict seismic design requirements enforced for the buildings constructed after 1999. In general, limited collapses and structural damage were observed. However, the economic losses due to nonstructural damage and business interruption were significant. There were no reports of damage to roads and bridges, and power, water, telecommunications, and other infrastructure and lifelines. This project encompasses the products of StEER’s response to this event: Preliminary Virtual Reconnaissance Report (PVRR).
Published: 2023

9. Genome Sequence of Genotype 1A Hepatovirus A Isolated from Plasma from a Haitian Child

Author: Alam, M. Mahbubul, Elbadry, Maha A., Loeb, Julia C., Stephenson, Caroline J., Louis, Rigan, Mavian, Carla, Charrel, Remi, Rahman, Sabita Rezwana, Morris, J. Glenn, and Lednicky, John A.
Subjects: Immunology and Microbiology (miscellaneous), Genetics, Molecular Biology
Abstract: Genotype 1A hepatovirus A was identified by quantitative reverse transcription-PCR and isolated from plasma from a Haitian child with acute undifferentiated febrile illness and malaise. The strain was most closely related to Brazilian strains, consistent with recognized patterns of virus movement in the Caribbean region.
Published: 2022

10. Health Prediction Analytics Using Deep Learning Methods and Applications

Author: Alam M. Afshar, Jain Sapna, Eiad Yafi, and Nevine Makrim Labib
Subjects: business.industry, Analytics, Computer science, Deep learning, Health care, Artificial intelligence, business, Data science
Published: 2021

11. Challenges of Artisanal Fishermen: A Case Study from Sonadia Island, Bangladesh

Author: Rahman, Md Mizanur, Alam, M, Rahman, Moshiur, Mamun, Mohammad, and Alam, Ashraful
Subjects: Marine conservation, Sustainable development, Economic growth, Civil society, Government, Research Methods in Life Sciences, Life Sciences, Marine Biology, Artisanal fishing, Biodiversity, Social and Behavioral Sciences, Artisanal Fishermen, Focus group, Local government, Business, Lagging, Marine Fisheries, SDGs, Rights, Pro-activeness, Government Department
Abstract: The southern part of Bangladesh is positioned on the orifice of Bay of Bengal and is abundant with marine fisheries' huge potential. Whereas marine resources are considered one of the essential sources of future economic development for many countries, Bangladesh is still lagging in this regard. The country cannot materialise full potentials of marine fisheries since more than 90% of fishers use artisanal fishing equipment, and the reasons behind being artisanal fishers are multifaceted. However, it is crucial to know the challenges of artisanal fishers in achieving Sustainable Development Goals (SDGs). This study explored the challenges associated with artisanal fisheries and finds out the solution to help achieve SDGs by providing recommendations. This study was conducted in one of the islands in Bangladesh's coastal area named Sonadia Island to unveil the challenges. Mainly primary data was collected through questionnaire and focus group discussion with the local government elected representative, fishermen association leader, representative of civil society and Upazila level government officials. Secondary data was used to analyse the regulatory and institutional framework. The targets of SDGs were aligned with the importance of artisanal fisheries and the rights of the fishermen. Piracy, local credit system, and complex market chain were identified as significant challenges. Pro-activeness of different government departments can improve the scenario drastically.
Published: 2022
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12. Agro-waste-based functionalized and economic adsorbents for the effective treatment of toxic contaminants from tannery effluent

Author: Kabir, MM, Nahar, N, Akter, MM, Alam, F, Gilroyed, BH, Misu, MM, Didar-ul-Alam, M, Hakim, M, Tijing, L, and Shon, HK
Subjects: Process Chemistry and Technology, 0905 Civil Engineering, 0907 Environmental Engineering, Safety, Risk, Reliability and Quality, Waste Management and Disposal, Biotechnology
Abstract: The present investigation explored two novel adsorbents, i.e., hydroxyapatite (HAP) and moringa-modified activated carbon (MMAC) from eggshell and moringa (Moringa oleifera) seeds, respectively, for the treatment of tannery effluents (TE). Particular emphasis was given to Cr(VI) adsorption when varying equilibration time, effluent pH, initial concentration of Cr(VI) and temperature. The adsorbents' characteristics suggested significant Cr(VI) accumulation onto the adsorbent's surface, whereas adsorption modelling recommended pseudo-second-order (PSO) and Langmuir models fitted well with the experimental data based on the regression coefficient (R2) values with minimum errors. The surface complexation model (SCM) indicated that speciation of Cr(VI) sorbed complexes formed an inner-sphere compound dominated by acidic pH, validated by pHpzc. The maximum adsorption capacities (qmax) of Cr(VI) were accounted to be 295 and 280 mg/g for HAP and MMAC, correspondingly. Interestingly, both adsorbents effectively removed other metallic ions; Fe, Pd, Cu and Zn removal was 85 %, while Cd, Ni, and Mn removal was 70 %. The Cr(VI) adsorption processes followed chemisorption mechanisms dominated by the surface complexation phenomenon. The performance of a 100 L packed-bed reactor was evaluated, and the breakthrough time of Cr(VI) adsorption for both adsorbents was 15 min. The adsorbents had splendid regeneration capacities and could be re-used numerous times. In essence, the present study concludes that both adsorbents are highly effective at removing Cr(VI) and other contaminants. The adsorbents are innovative and economical and can be one of the breakthrough feasible options for treating toxic contaminants in a large-scale TE.
Published: 2023

13. Bioactive Compounds and Biochemical and Antioxidant Properties of Selected Minor Indigenous Fruits in Bangladesh

Author: Khan M.H.H, Nasrin T.A.A, Alam M, Islam M.M, Molla M.M, Khatun A, Sabuz A.A, and Chowdhury M.G.F
Subjects: Antioxidant, Traditional medicine, medicine.medical_treatment, Geography, Planning and Development, medicine, Soil Science, Plant Science, Biology, Agronomy and Crop Science, Indigenous
Abstract: Minor fruits are a potential source of antinutrients, but there is no complete primary data source in the Bangladeshi context. Therefore, the present study was undertaken to acquire documentation for a database of the composition of selected minor fruits. The total phenolic (TPH), vitamin C, total carotene, and ß-carotene contents and antioxidant activity of selected minor fruits were determined by 1,1-diphenyl-2picryl hydrazyl (DPPH) scavenging and reducing power assays (RPA). Phenolic compounds were assessed using high-performance liquid chromatography coupled with a photodiode array detector and autosampler. Results revealed that minor fruits contain different phytochemicals, particularly TPH, ascorbic acid, total flavonoid (TF), ß-carotene, total carotenoid (TC), and total anthocyanin content (TAC); values ranged, respectively, 0.23-176.50 mg GAE/g, 16.67-664.92 mg/100 g, 2.26-150.02 mg QE/100 g, 1.41-6897.57 µg/100 g, 1.26-98.24 mg/100 g and 1.15-47.46 mg/100 g. In the parameters antioxidant activity, total antioxidant capacity, DPPH, reducing power capacity (RPC), ferric reducing antioxidant power (FRAP), metal chelating capacity (MCC), nitric oxide (NO), and free radical scavenging activity, IC50 ranged 0.01-278.24 µg of ascorbic acid/mg of extract, 39.70-250.00%, 3.21-634.00%, 0.02-1817.88 µM Fe2SO4/100g, 22.29-210.43%, 0.02-70.50%, and 4.98-856.70 µg/g, respectively. Among the identified and quantified phenolic acids, leading examples were gallic acid (279.06 mg/100 g), vanilic acid (43.77 mg/100 g), Þ-courmaric acid (178.96 mg/100 g), ferulic acid (20.44 mg/100 g), and lutein (91.13 µg/100 g) in aonla, day fruit, elephant apple, and bilimbi. Moreover, all selected minor fruits are rich sources of bioactive, biochemical, and antioxidant compounds with potential for use in therapeutic applications.
Published: 2021

14. Complete mitochondrial genome sequence of Black Bengal goat (Capra hircus)

Author: Siddiki, A, Billah, M, Alam, M, Shawrob, KSM, Kumkum, M, Saha, S, Chowdhury, Muntaha, Rahman, Atif H, Stear, Michael, Khan, MKI, Miah, G, M.Mollah, AK, and Baten, A
Subjects: Uncategorized
Abstract: The Black Bengal goat (Capra hircus), is a native breed found in Bangladesh, popular due to its economic contribution. Here, we report the complete mitochondrial genome sequence of Black Bengal goat. The circular genome is 16,640 bp long, comprising of 60.89% AT content. The genome contains 37 genes, consisting of 13 protein-coding genes, 22 tRNA genes, two rRNA genes, and a control region (D-loop).
Published: 2022
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15. Impact of reaction temperatures on the particle size of V2O5 synthesized by facile hydrothermal technique and their auspicious photocatalytic performance in dye degradation

Author: Jalil, M. A., Khan, M. N. I., Mandal, S., Chowdhury, F. -U. -Z., Hossain, M. M., Jana, D., Alam, M. S., and Uddin, M. M.
Subjects: Condensed Matter - Materials Science, Materials Science (cond-mat.mtrl-sci), FOS: Physical sciences
Abstract: In this study, a complete study of the effect of hydrothermal reaction temperatures on the synthesis and physical properties of V2O5 using the green facile mild hydrothermal method has been performed with six different temperatures 100 {\deg}C to 200 {\deg}C, in the step of 20 {\deg}C. . The XRD pattern confirm the stable orthorhombic crystal structure of the synthesized samples at all reaction temperatures. The SEM and TEM images demonstrate the particle-like morphology, and these characterizations affirmed that the particles size became larger with the increase of reaction temperatures. The FTIR analysis is employed to study the functional groups, and the obtained results are consistent with the XRD analysis. The bandgap has been estimated at various reaction temperatures using UV-vis diffuse reflectance spectra (UV-DRS) and was found to be varied 2.09 eV to 2.15 eV that are suitable range to absorb a significant amount of visible light. The photocatalysis of methylene blue (MB) with synthesized samples has been accomplished to investigate photocatalytic efficiency. The pure V2O5 synthesized at lower reaction temperature (100 {\deg}C) possess a lower bandgap and, accordingly, higher photocatalytic efficiency., Comment: 19 pages
Published: 2022
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16. Quantum computing hardware for HEP algorithms and sensing

Author: Alam, M. Sohaib, Belomestnykh, Sergey, Bornman, Nicholas, Cancelo, Gustavo, Chao, Yu-Chiu, Checchin, Mattia, Dinh, Vinh San, Grassellino, Anna, Gustafson, Erik J., Harnik, Roni, McRae, Corey Rae Harrington, Huang, Ziwen, Kapoor, Keshav, Kim, Taeyoon, Kowalkowski, James B., Kramer, Matthew J., Krasnikova, Yulia, Kumar, Prem, Kurkcuoglu, Doga Murat, Lamm, Henry, Lyon, Adam L., Milathianaki, Despina, Murthy, Akshay, Mutus, Josh, Nekrashevich, Ivan, Oh, JinSu, Özgüler, A. Barış, Perdue, Gabriel Nathan, Reagor, Matthew, Romanenko, Alexander, Sauls, James A., Stefanazzi, Leandro, Tubman, Norm M., Venturelli, Davide, Wang, Changqing, You, Xinyuan, van Zanten, David M. T., Zhou, Lin, Zhu, Shaojiang, and Zorzetti, Silvia
Subjects: Quantum Physics, High Energy Physics - Experiment (hep-ex), FOS: Physical sciences, Quantum Physics (quant-ph), High Energy Physics - Experiment
Abstract: Quantum information science harnesses the principles of quantum mechanics to realize computational algorithms with complexities vastly intractable by current computer platforms. Typical applications range from quantum chemistry to optimization problems and also include simulations for high energy physics. The recent maturing of quantum hardware has triggered preliminary explorations by several institutions (including Fermilab) of quantum hardware capable of demonstrating quantum advantage in multiple domains, from quantum computing to communications, to sensing. The Superconducting Quantum Materials and Systems (SQMS) Center, led by Fermilab, is dedicated to providing breakthroughs in quantum computing and sensing, mediating quantum engineering and HEP based material science. The main goal of the Center is to deploy quantum systems with superior performance tailored to the algorithms used in high energy physics. In this Snowmass paper, we discuss the two most promising superconducting quantum architectures for HEP algorithms, i.e. three-level systems (qutrits) supported by transmon devices coupled to planar devices and multi-level systems (qudits with arbitrary N energy levels) supported by superconducting 3D cavities. For each architecture, we demonstrate exemplary HEP algorithms and identify the current challenges, ongoing work and future opportunities. Furthermore, we discuss the prospects and complexities of interconnecting the different architectures and individual computational nodes. Finally, we review several different strategies of error protection and correction and discuss their potential to improve the performance of the two architectures. This whitepaper seeks to reach out to the HEP community and drive progress in both HEP research and QIS hardware., Comment: contribution to Snowmass 2021
Published: 2022
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17. On the Impact of Temporal Representations on Metaphor Detection

Author: Ottolina, G, Palmonari, M, Vimercati, M, Alam, M, Calzolari, N, Béchet, F, Blache, P, Choukri, K, Cieri, C, Declerck, T, Goggi, S, Isahara, H, Maegaard, B, Mariani, J, Mazo, H, Odijk, J, Piperidis, S, Ottolina, G, Palmonari, M, Vimercati, M, and Alam, M
Subjects: FOS: Computer and information sciences, Computer Science - Computation and Language, Artificial Intelligence (cs.AI), Computer Science - Artificial Intelligence, Methaphor Detection, Word Embedding, SWEAT, Computation and Language (cs.CL)
Abstract: State-of-the-art approaches for metaphor detection compare their literal - or core - meaning and their contextual meaning using metaphor classifiers based on neural networks. However, metaphorical expressions evolve over time due to various reasons, such as cultural and societal impact. Metaphorical expressions are known to co-evolve with language and literal word meanings, and even drive, to some extent, this evolution. This poses the question of whether different, possibly time-specific, representations of literal meanings may impact the metaphor detection task. To the best of our knowledge, this is the first study that examines the metaphor detection task with a detailed exploratory analysis where different temporal and static word embeddings are used to account for different representations of literal meanings. Our experimental analysis is based on three popular benchmarks used for metaphor detection and word embeddings extracted from different corpora and temporally aligned using different state-of-the-art approaches. The results suggest that the usage of different static word embedding methods does impact the metaphor detection task and some temporal word embeddings slightly outperform static methods. However, the results also suggest that temporal word embeddings may provide representations of the core meaning of the metaphor even too close to their contextual meaning, thus confusing the classifier. Overall, the interaction between temporal language evolution and metaphor detection appears tiny in the benchmark datasets used in our experiments. This suggests that future work for the computational analysis of this important linguistic phenomenon should first start by creating a new dataset where this interaction is better represented., Comment: 12 pages, 4 figures
Published: 2021
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18. Pulmonary artery capacitance a simple and novel prognostic variable in acute pulmonary embolism

Author: Quintero-Martinez, J. A., Cordova, S. N., Alam, M. M., Jain, V., Vlazny, D. T., Houghton, D. E., Ana Casanegra, Wysokinski, W. E., and Villarraga, H. R.
Subjects: Cardiology and Cardiovascular Medicine
Abstract: Background The non-invasive calculation of right ventricular hemodynamics such as the pulmonary artery capacitance (PAC) has proven to be feasible and easy to perform. The simplified pulmonary embolism severity index (sPESI) and pulmonary vascular resistance (PVR) are other prognostic tools that have been used in the past. Purpose To evaluate if baseline PAC can outperform PVR and sPESI to predict all-cause short-term mortality in patients with acute pulmonary embolism (PE). Methods 373 patients with acute PE and a transthoracic echocardiogram performed within one day of diagnosis from March 2013 through June 2020 were followed prospectively. PAC was calculated as: Left ventricular stroke volume/ (Pulmonary artery systolic pressure – Pulmonary artery diastolic pressure). PVR was calculated as: Tricuspid regurgitant velocity / Right ventricular outflow tract velocity time integral x 10 + 0.16. The sPESI was used to evaluate prognosis by categorizing patients into low and high-risk categories. Multiple logistic regression analyses and receiver-operating characteristic curves were used to evaluate the ability of PAC, PVR, and sPESI to predict all-cause mortality up to six months. The Youden index was used to determine the cut-off value with the highest sensitivity and specificity. Kaplan–Meier curves were performed to determine event-free survival rate, differences between groups were assessed using the Wilcoxon Test. Results Mean age was 64±15 years (58% male, 28% cancer). PAC was associated with mortality at thirty days (p 0.0003), three months (p 0.003), and six months (p 0.011) (Table). PVR was associated with mortality at thirty days, three months, and six months (p 0.045, 0.012, and 0.031 respectively). The sPESI score ≥1 (high risk) was associated with all-cause mortality at three months and six months (p 0.0136 and Conclusion In patients with acute PE, PAC outperforms sPESI and PVR as a predictor of short-term all-cause mortality at thirty days, three months, and six months. These three variables should be explored head to head prospectively for their utility to predict short term all-cause mortality. Funding Acknowledgement Type of funding sources: None.
Published: 2021

19. Measurements of the Absolute Branching Fractions of B^{±}→K^{±}X_{cc[over ¯]}

Author: Lees, J. P., Poireau, V., Tisserand, V., Grauges, E., Palano, A., Eigen, G., Brown, D. N., Kolomensky, Y. G., Fritsch, M., Koch, H., Schroeder, T., Cheaib, R., Hearty, C., Mattison, T. S., Mckenna, J. A., R. Y., So, Blinov, V. E., Buzykaev, A. R., Druzhinin, V. P., Golubev, V. B., Kozyrev, E. A., Kravchenko, E. A., Onuchin, A. P., Serednyakov, S. I., Skovpen, Y. I., Solodov, E. P., Todyshev, K. Y., Lankford, A. J., Dey, B., Gary, J. W., Long, O., Eisner, A. M., Lockman, W. S., Panduro Vazquez, W., Chao, D. S., Cheng, C. H., Echenard, B., Flood, K. T., Hitlin, D. G., Kim, J., Li, Y., Miyashita, T. S., Ongmongkolkul, P., Porter, F. C., Rohrken, M., Huard, Z., Meadows, B. T., Pushpawela, B. G., Sokoloff, M. D., Sun, L., Smith, J. G., Wagner, S. R., Bernard, D., Verderi, M., Bettoni, D., Bozzi, C., Calabrese, R., Cibinetto, G., Fioravanti, E., Garzia, I., Luppi, E., Santoro, V., Calcaterra, A., De Sangro, R., Finocchiaro, G., Martellotti, S., Patteri, P., Peruzzi, I. M., Piccolo, M., Rotondo, M., Zallo, A., Passaggio, S., Patrignani, C., Shuve, B. J., Lacker, H. M., Bhuyan, B., Mallik, U., Chen, C., Cochran, J., Prell, S., Gritsan, A. V., Arnaud, N., Davier, M., Le Diberder, F., Lutz, A. M., Wormser, G., Lange, D. J., Wright, D. M., Coleman, J. P., Gabathuler, E., Hutchcroft, D. E., Payne, D. J., Touramanis, C., Bevan, A. J., Di Lodovico, F., Sacco, R., Cowan, G., Banerjee, S., Davis, C. L., Denig, A. G., Gradl, W., Griessinger, K., Hafner, A., Schubert, K. R., Barlow, R. J., Lafferty, G. D., Cenci, R., Jawahery, A., Roberts, D. A., Cowan, R., Robertson, S. H., Seddon, R. M., Neri, N., Palombo, F., Cremaldi, L., Godang, R., Summers, D. J., Taras, P., De Nardo, G., Sciacca, C., Raven, G., Jessop, C. P., Losecco, J. M., Honscheid, K., Kass, R., Gaz, A., Margoni, M., Posocco, M., Simi, G., Simonetto, F., Stroili, R., Akar, S., Ben-Haim, E., Bomben, M., Bonneaud, G. R., Calderini, G., Chauveau, J., Marchiori, G., Ocariz, J., Biasini, M., Manoni, E., Rossi, A., Batignani, G., Bettarini, S., Carpinelli, M., Casarosa, G., Chrzaszcz, M., Forti, F., Giorgi, M. A., Lusiani, A., Oberhof, B., Paoloni, E., Rama, M., Rizzo, G., Walsh, J. J., Zani, L., Smith, A. J. S., Anulli, F., Faccini, R., Ferrarotto, F., Ferroni, F., Pilloni, A., Piredda, G., Bunger, C., Dittrich, S., Grunberg, O., Hess, M., Leddig, T., Voss, C., Waldi, R., Adye, T., Wilson, F. F., Emery, S., Vasseur, G., Aston, D., Cartaro, C., Convery, M. R., Dorfan, J., Dunwoodie, W., Ebert, M., Field, R. C., Fulsom, B. G., Graham, M. T., Hast, C., Innes, W. R., Kim, P., Leith, D. W. G. S., Luitz, S., Macfarlane, D. B., Muller, D. R., Neal, H., Ratcliff, B. N., Roodman, A., Sullivan, M. K., Va'Vra, J., Wisniewski, W. J., Purohit, M. V., Wilson, J. R., Randle-Conde, A., Sekula, S. J., Ahmed, H., Bellis, M., Burchat, P. R., Puccio, E. M. T., Alam, M. S., Ernst, J. A., Gorodeisky, R., Guttman, N., Peimer, D. R., Soffer, A., Spanier, S. M., Ritchie, J. L., Schwitters, R. F., Izen, J. M., Lou, X. C., Bianchi, F., De Mori, F., Filippi, A., Gamba, D., Lanceri, L., Vitale, L., Martinez-Vidal, F., Oyanguren, A., Albert, J., Beaulieu, A., Bernlochner, F. U., King, G. J., Kowalewski, R., Lueck, T., Nugent, I. M., Roney, J. M., Sobie, R. J., Tasneem, N., Gershon, T. J., Harrison, P. F., Latham, T. E., Prepost, R., S. L., Wu, Lees, J P, Poireau, V, Tisserand, V, Grauges, E, Palano, A, Eigen, G, Brown, D N, Kolomensky, Yu G, Fritsch, M, Koch, H, Schroeder, T, Cheaib, R, Hearty, C, Mattison, T S, Mckenna, J A, So, R Y, Blinov, V E, Buzykaev, A R, Druzhinin, V P, Golubev, V B, Kozyrev, E A, Kravchenko, E A, Onuchin, A P, Serednyakov, S I, Skovpen, Yu I, Solodov, E P, Todyshev, K Yu, Lankford, A J, Dey, B, Gary, J W, Long, O, Eisner, A M, Lockman, W S, Panduro Vazquez, W, Chao, D S, Cheng, C H, Echenard, B, Flood, K T, Hitlin, D G, Kim, J, Li, Y, Miyashita, T S, Ongmongkolkul, P, Porter, F C, Röhrken, M, Huard, Z, Meadows, B T, Pushpawela, B G, Sokoloff, M D, Sun, L, Smith, J G, Wagner, S R, Bernard, D, Verderi, M, Bettoni, D, Bozzi, C, Calabrese, R, Cibinetto, G, Fioravanti, E, Garzia, I, Luppi, E, Santoro, V, Calcaterra, A, de Sangro, R, Finocchiaro, G, Martellotti, S, Patteri, P, Peruzzi, I M, Piccolo, M, Rotondo, M, Zallo, A, Passaggio, S, Patrignani, C, Shuve, B J, Lacker, H M, Bhuyan, B, Mallik, U, Chen, C, Cochran, J, Prell, S, Gritsan, A V, Arnaud, N, Davier, M, Le Diberder, F, Lutz, A M, Wormser, G, Lange, D J, Wright, D M, Coleman, J P, Gabathuler, E, Hutchcroft, D E, Payne, D J, Touramanis, C, Bevan, A J, Di Lodovico, F, Sacco, R, Cowan, G, Banerjee, Sw, Davis, C L, Denig, A G, Gradl, W, Griessinger, K, Hafner, A, Schubert, K R, Barlow, R J, Lafferty, G D, Cenci, R, Jawahery, A, Roberts, D A, Cowan, R, Robertson, S H, Seddon, R M, Neri, N, Palombo, F, Cremaldi, L, Godang, R, Summers, D J, Taras, P, De Nardo, G, Sciacca, C, Raven, G, Jessop, C P, Losecco, J M, Honscheid, K, Kass, R, Gaz, A, Margoni, M, Posocco, M, Simi, G, Simonetto, F, Stroili, R, Akar, S, Ben-Haim, E, Bomben, M, Bonneaud, G R, Calderini, G, Chauveau, J, Marchiori, G, Ocariz, J, Biasini, M, Manoni, E, Rossi, A, Batignani, G, Bettarini, S, Carpinelli, M, Casarosa, G, Chrzaszcz, M, Forti, F, Giorgi, M A, Lusiani, A, Oberhof, B, Paoloni, E, Rama, M, Rizzo, G, Walsh, J J, Zani, L, Smith, A J S, Anulli, F, Faccini, R, Ferrarotto, F, Ferroni, F, Pilloni, A, Piredda, G, Bünger, C, Dittrich, S, Grünberg, O, Heß, M, Leddig, T, Voß, C, Waldi, R, Adye, T, Wilson, F F, Emery, S, Vasseur, G, Aston, D, Cartaro, C, Convery, M R, Dorfan, J, Dunwoodie, W, Ebert, M, Field, R C, Fulsom, B G, Graham, M T, Hast, C, Innes, W R, Kim, P, Leith, D W G S, Luitz, S, Macfarlane, D B, Muller, D R, Neal, H, Ratcliff, B N, Roodman, A, Sullivan, M K, Va'Vra, J, Wisniewski, W J, Purohit, M V, Wilson, J R, Randle-Conde, A, Sekula, S J, Ahmed, H, Bellis, M, Burchat, P R, Puccio, E M T, Alam, M S, Ernst, J A, Gorodeisky, R, Guttman, N, Peimer, D R, Soffer, A, Spanier, S M, Ritchie, J L, Schwitters, R F, Izen, J M, Lou, X C, Bianchi, F, De Mori, F, Filippi, A, Gamba, D, Lanceri, L, Vitale, L, Martinez-Vidal, F, Oyanguren, A, Albert, J, Beaulieu, A, Bernlochner, F U, King, G J, Kowalewski, R, Lueck, T, Nugent, I M, Roney, J M, Sobie, R J, Tasneem, N, Gershon, T J, Harrison, P F, Latham, T E, Prepost, R, and Wu, S L
Subjects: charmonium physics, B decays, inclusive measurements
Abstract: A study of the two-body decays B^{±}→X_{cc[over ¯]}K^{±}, where X_{cc[over ¯]} refers to one charmonium state, is reported by the BABAR Collaboration using a data sample of 424 fb^{-1}. The absolute determination of branching fractions for these decays are significantly improved compared to previous BABAR measurements. Evidence is found for the decay B^{+}→X(3872)K^{+} at the 3σ level. The absolute branching fraction B[B^{+}→X(3872)K^{+}]=[2.1±0.6(stat)±0.3(syst)]×10^{-4} is measured for the first time. It follows that B[X(3872)→J/ψπ^{+}π^{-}]=(4.1±1.3)%, supporting the hypothesis of a molecular component for this resonance.
Published: 2020

20. Identification of 1, 2, 4-Triazine and Its Derivatives against Lanosterol 14 - Demethylase (CYP51) Property of Candida Albicans: Influence on the Development of New Antifungal Therapeutic Strategies

Author: Verma Ak, Ameta S, Vishwakarma Nk, Srivastava Ak, Alam M, Yadav Vk, Upadhyay Sk, Teli Pk, Bhojiya Aa, Harina H, Ashid M, Ahmed Sf, Hossain Ms, and Majid A
Subjects: Antifungal, biology, medicine.drug_class, Lanosterol, medicinal_chemistry, biology.organism_classification, chemistry.chemical_compound, chemistry, Biochemistry, medicine, biology.protein, Demethylase, Candida albicans, Triazine
Abstract: This research aims to find out whether the synthetic 1, 2, 4-triazine and its derivatives have antifungal effects and can protect humans from infection with Candida albicans. Molecular docking and molecular dynamic simulation are widely used in modern drug design to target a We are interested in using molecular docking and molecular dynamics modelling to investigate the interaction between the derivatives of 1, 2, 4-triazine and the resulting lanosterol 14 - demethylase (CYP51) of Candida albicans The inhibition of Candida albicans CYP51 is the main goal of our research. The 1, 2, 4-triazine and its derivatives have been docked to the CYP51 enzyme, which is involved in Candida albicans Multidrug Drug Resistance (MDR). Autodock tools were used to identifying the binding affinities of molecules against the target proteins. Compared to conventional fluconazole, the molecular docking results indicated that each drug has a high binding affinity for CYP51 proteins and forms unbound interactions and hydrogen bonds with their active residues and surrounding allosteric residues. The docking contacts were made using a 10 ns MD simulation with nine molecules. RMSD, RMSF, hydrogen bonds, and the Rg all confirm these conclusions. In addition, these compounds were expected to have a favorable pharmacological profile and low toxicity. The compounds are being offered as scaffolds for the development of new antifungal drugs and as candidates for future in vitro testing.
Published: 2021

21. Exploring Molecular Approaches in Amyotrophic Lateral Sclerosis: Drug Targets from Clinical and Pre-Clinical Findings

Author: null Alam, M
Subjects: Pharmacology, Drug Discovery, Molecular Medicine
Published: 2021

22. Rhupus Syndrome: Overlap of Rheumatoid Arthritis and Systemic Lupus Erythematosus

Author: Ijaz Y, Ahmed D, Alam M, Tipu Hn, Arshad Z, and Hussain M
Subjects: medicine.medical_specialty, business.industry, Rheumatoid arthritis, Medicine, skin and connective tissue diseases, business, medicine.disease, Dermatology
Abstract: Rhupus syndrome is a rare and incompletely described autoimmune entity in which the same patient sequentially develops symptoms both of Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE). Both diseases have different diagnostic criteria and laboratory investigations but have mixed clinical presentation so can easily miss the rhupus syndrome. Overlap phenomenon is common in various autoimmune diseases which otherwise differ in presentation, treatment response and prognosis. RA and SLE overlap is very rarely reported and no rational criteria for its diagnosis and treatment strategy are finalized yet. In most of the reported cases of Rhupus syndrome, RA appeared first and SLE developed later while in a small number of cases SLE appeared first which later evolved to RA and in a few cases symptoms of both diseases appeared simultaneously. A 55-years old female patient was diagnosed with RA four years back and recently developed oral ulcers, anemia, leucopenia and thrombocytopenia. After complete history, general physical examination, laboratory investigations and fulfillment of SLE (SLICC criteria 2012) and (ACR criteria 2010) for RA, a final diagnosis of Rhupus syndrome was established.
Published: 2021

23. Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Author: Collier, D. A., De Marco, A., Ferreira, I. A. T. M., Meng, B., Datir, R. P., Walls, A. C., Kemp, S. A., Bassi, J., Pinto, D., Silacci-Fregni, C., Bianchi, S., Tortorici, M. A., Bowen, J., Culap, K., Jaconi, S., Cameroni, E., Snell, G., Pizzuto, M. S., Pellanda, A. F., Garzoni, C., Riva, A., Baker, S., Dougan, G., Hess, C., Kingston, N., Lehner, P. J., Lyons, P. A., Matheson, N. J., Owehand, W. H., Saunders, C., Summers, C., Thaventhiran, J. E. D., Toshner, M., Weekes, M. P., Bucke, A., Calder, J., Canna, L., Domingo, J., Elmer, A., Fuller, S., Harris, J., Hewitt, S., Kennet, J., Jose, S., Kourampa, J., Meadows, A., O'Brien, C., Price, J., Publico, C., Rastall, R., Ribeiro, C., Rowlands, J., Ruffolo, V., Tordesillas, H., Bullman, B., Dunmore, B. J., Fawke, S., Graf, S., Hodgson, J., Huang, C., Hunter, K., Jones, E., Legchenko, E., Matara, C., Martin, J., Mescia, F., O'Donnell, C., Pointon, L., Pond, N., Shih, J., Sutcliffe, R., Tilly, T., Treacy, C., Tong, Z., Wood, J., Wylot, M., Bergamaschi, L., Betancourt, A., Bower, G., Cossetti, C., De Sa, A., Epping, M., Grenfell, R., Hinch, A., Huhn, O., Jackson, S., Jarvis, I., Lewis, D., Marsden, J., Nice, F., Okecha, G., Omarjee, O., Perera, M., Richoz, N., Romashova, V., Yarkoni, N. S., Sharma, R., Stefanucci, L., Stephens, J., Strezlecki, M., Turner, L., De Bie, E. M. D. D., Bunclark, K., Josipovic, M., Mackay, M., Rossi, S., Selvan, M., Spencer, S., Yong, C., Ansaripour, A., Michael, A., Mwaura, L., Patterson, C., Polwarth, G., Polgarova, P., di Stefano, G., Fahey, C., Michel, R., Bong, S. -H., Coudert, J. D., Holmes, E., Allison, J., Butcher, H., Caputo, D., Clapham-Riley, D., Dewhurst, E., Furlong, A., Graves, B., Gray, J., Ivers, T., Kasanicki, M., Le Gresley, E., Linger, R., Meloy, S., Muldoon, F., Ovington, N., Papadia, S., Phelan, I., Stark, H., Stirrups, K. E., Townsend, P., Walker, N., Webster, J., Mccoy, L. E., Smith, K. G. C., Bradley, J. R., Temperton, N., Ceron-Gutierrez, L., Barcenas-Morales, G., Robson, S. C., Loman, N. J., Connor, T. R., Golubchik, T., Martinez Nunez, R. T., Ludden, C., Corden, S., Johnston, I., Bonsall, D., Smith, C. P., Awan, A. R., Bucca, G., Torok, M. E., Saeed, K., Prieto, J. A., Jackson, D. K., Hamilton, W. L., Snell, L. B., Moore, C., Harrison, E. M., Goncalves, S., Fairley, D. J., Loose, M. W., Watkins, J., Livett, R., Moses, S., Amato, R., Nicholls, S., Bull, M., Smith, D. L., Barrett, J., Aanensen, D. M., Curran, M. D., Parmar, S., Aggarwal, D., Shepherd, J. G., Parker, M. D., Glaysher, S., Bashton, M., Underwood, A. P., Pacchiarini, N., Loveson, K. F., Carabelli, A. M., Templeton, K. E., Langford, C. F., Sillitoe, J., de Silva, T. I., Wang, D., Kwiatkowski, D., Rambaut, A., O'Grady, J., Cottrell, S., Holden, M. T. G., Thomson, E. C., Osman, H., Andersson, M., Chauhan, A. J., Hassan-Ibrahim, M. O., Lawniczak, M., Alderton, A., Chand, M., Constantinidou, C., Unnikrishnan, M., Darby, A. C., Hiscox, J. A., Paterson, S., Martincorena, I., Robertson, D. L., Volz, E. M., Page, A. J., Pybus, O. G., Bassett, A. R., Ariani, C. V., Spencer Chapman, M. H., K. K., Li, Shah, R. N., Jesudason, N. G., Taha, Y., Mchugh, M. P., Dewar, R., Jahun, A. S., Mcmurray, C., Pandey, S., Mckenna, J. P., Nelson, A., Young, G. R., Mccann, C. M., Elliott, S., Lowe, H., Temperton, B., Roy, S., Price, A., Rey, S., Wyles, M., Rooke, S., Shaaban, S., de Cesare, M., Letchford, L., Silveira, S., Pelosi, E., Wilson-Davies, E., Hosmillo, M., O'Toole, A., Hesketh, A. R., Stark, R., du Plessis, L., Ruis, C., Adams, H., Bourgeois, Y., Michell, S. L., Gramatopoulos, D., Edgeworth, J., Breuer, J., Todd, J. A., Fraser, C., Buck, D., John, M., Kay, G. L., Palmer, S., Peacock, S. J., Heyburn, D., Weldon, D., Robinson, E., Mcnally, A., Muir, P., Vipond, I. B., Boyes, J., Sivaprakasam, V., Salluja, T., Dervisevic, S., Meader, E. J., Park, N. R., Oliver, K., Jeffries, A. R., Ott, S., da Silva Filipe, A., Simpson, D. A., Williams, C., Masoli, J. A. H., Knight, B. A., Jones, C. R., Koshy, C., Ash, A., Casey, A., Bosworth, A., Ratcliffe, L., Xu-McCrae, L., Pymont, H. M., Hutchings, S., Berry, L., Jones, K., Halstead, F., Davis, T., Holmes, C., Iturriza-Gomara, M., Lucaci, A. O., Randell, P. A., Cox, A., Madona, P., Harris, K. A., Brown, J. R., Mahungu, T. W., Irish-Tavares, D., Haque, T., Hart, J., Witele, E., Fenton, M. L., Liggett, S., Graham, C., Swindells, E., Collins, J., Eltringham, G., Campbell, S., Mcclure, P. C., Clark, G., Sloan, T. J., Jones, C., Lynch, J., Warne, B., Leonard, S., Durham, J., Williams, T., Haldenby, S. T., Storey, N., Alikhan, N. -F., Holmes, N., Carlile, M., Perry, M., Craine, N., Lyons, R. A., Beckett, A. H., Goudarzi, S., Fearn, C., Cook, K., Dent, H., Paul, H., Davies, R., Blane, B., Girgis, S. T., Beale, M. A., Bellis, K. L., Dorman, M. J., Drury, E., Kane, L., Kay, S., Mcguigan, S., Nelson, R., Prestwood, L., Rajatileka, S., Batra, R., Williams, R. J., Kristiansen, M., Green, A., Justice, A., Mahanama, A. I. K., Samaraweera, B., Hadjirin, N. F., Quick, J., Poplawski, R., Kermack, L. M., Reynolds, N., Hall, G., Chaudhry, Y., Pinckert, M. L., Georgana, I., Moll, R. J., Thornton, A., Myers, R., Stockton, J., Williams, C. A., Yew, W. C., Trotter, A. J., Trebes, A., MacIntyre-Cockett, G., Birchley, A., Adams, A., Plimmer, A., Gatica-Wilcox, B., Mckerr, C., Hilvers, E., Jones, H., Asad, H., Coombes, J., Evans, J. M., Fina, L., Gilbert, L., Graham, L., Cronin, M., Kumziene-Summerhayes, S., Taylor, S., Jones, S., Groves, D. C., Zhang, P., Gallis, M., Louka, S. F., Starinskij, I., Jackson, C., Gourtovaia, M., Tonkin-Hill, G., Lewis, K., Tovar-Corona, J. M., James, K., Baxter, L., Alam, M. T., Orton, R. J., Hughes, J., Vattipally, S., Ragonnet-Cronin, M., Nascimento, F. F., Jorgensen, D., Boyd, O., Geidelberg, L., Zarebski, A. E., Raghwani, J., Kraemer, M. U. G., Southgate, J., Lindsey, B. B., Freeman, T. M., Keatley, J. -P., Singer, J. B., de Oliveira Martins, L., Yeats, C. A., Abudahab, K., Taylor, B. E. W., Menegazzo, M., Danesh, J., Hogsden, W., Eldirdiri, S., Kenyon, A., Mason, J., Robinson, T. I., Holmes, A., Hartley, J. A., Curran, T., Mather, A. E., Shankar, G., Jones, R., Howe, R., Morgan, S., Wastenge, E., Chapman, M. R., Mookerjee, S., Stanley, R., Smith, W., Peto, T., Eyre, D., Crook, D., Vernet, G., Kitchen, C., Gulliver, H., Merrick, I., Guest, M., Munn, R., Bradley, D. T., Wyatt, T., Beaver, C., Foulser, L., Churcher, C. M., Brooks, E., Smith, K. S., Galai, K., Mcmanus, G. M., Bolt, F., Coll, F., Meadows, L., Attwood, S. W., Davies, A., De Lacy, E., Downing, F., Edwards, S., Scarlett, G. P., Jeremiah, S., Smith, N., Leek, D., Sridhar, S., Forrest, S., Cormie, C., Gill, H. K., Dias, J., Higginson, E. E., Maes, M., Young, J., Wantoch, M., Jamrozy, D., Lo, S., Patel, M., Hill, V., Bewshea, C. M., Ellard, S., Auckland, C., Harrison, I., Bishop, C., Chalker, V., Richter, A., Beggs, A., Best, A., Percival, B., Mirza, J., Megram, O., Mayhew, M., Crawford, L., Ashcroft, F., Moles-Garcia, E., Cumley, N., Hopes, R., Asamaphan, P., Niebel, M. O., Gunson, R. N., Bradley, A., Maclean, A., Mollett, G., Blacow, R., Bird, P., Helmer, T., Fallon, K., Tang, J., Hale, A. D., Macfarlane-Smith, L. R., Harper, K. L., Carden, H., Machin, N. W., Jackson, K. A., Ahmad, S. S. Y., George, R. P., Turtle, L., O'Toole, E., Watts, J., Breen, C., Cowell, A., Alcolea-Medina, A., Charalampous, T., Patel, A., Levett, L. J., Heaney, J., Rowan, A., Taylor, G. P., Shah, D., Atkinson, L., Lee, J. C. D., Westhorpe, A. P., Jannoo, R., Lowe, H. L., Karamani, A., Ensell, L., Chatterton, W., Pusok, M., Dadrah, A., Symmonds, A., Sluga, G., Molnar, Z., Baker, P., Bonner, S., Essex, S., Barton, E., Padgett, D., Scott, G., Greenaway, J., Payne, B. A. I., Burton-Fanning, S., Waugh, S., Raviprakash, V., Sheriff, N., Blakey, V., Williams, L. -A., Moore, J., Stonehouse, S., Smith, L., Davidson, R. K., Bedford, L., Coupland, L., Wright, V., Chappell, J. G., Tsoleridis, T., Ball, J., Khakh, M., Fleming, V. M., Lister, M. M., Howson-Wells, H. C., Boswell, T., Joseph, A., Willingham, I., Duckworth, N., Walsh, S., Wise, E., Moore, N., Mori, M., Cortes, N., Kidd, S., Williams, R., Gifford, L., Bicknell, K., Wyllie, S., Lloyd, A., Impey, R., Malone, C. S., Cogger, B. J., Levene, N., Monaghan, L., Keeley, A. J., Partridge, D. G., Raza, M., Evans, C., Johnson, K., Betteridge, E., Farr, B. W., Goodwin, S., Quail, M. A., Scott, C., Shirley, L., Thurston, S. A. J., Rajan, D., Bronner, I. F., Aigrain, L., Redshaw, N. M., Lensing, S. V., Mccarthy, S., Makunin, A., Balcazar, C. E., Gallagher, M. D., Williamson, K. A., Stanton, T. D., Michelsen, M. L., Warwick-Dugdale, J., Manley, R., Farbos, A., Harrison, J. W., Sambles, C. M., Studholme, D. J., Lackenby, A., Mbisa, T., Platt, S., Miah, S., Bibby, D., Manso, C., Hubb, J., Dabrera, G., Ramsay, M., Bradshaw, D., Schaefer, U., Groves, N., Gallagher, E., Lee, D., Williams, D., Ellaby, N., Hartman, H., Manesis, N., Patel, V., Ledesma, J., Twohig, K. A., Allara, E., Pearson, C., Cheng, J. K. J., Bridgewater, H. E., Frost, L. R., Taylor-Joyce, G., Brown, P. E., Tong, L., Broos, A., Mair, D., Nichols, J., Carmichael, S. N., Smollett, K. L., Nomikou, K., Aranday-Cortes, E., Johnson, N., Nickbakhsh, S., Vamos, E. E., Hughes, M., Rainbow, L., Eccles, R., Nelson, C., Whitehead, M., Gregory, R., Gemmell, M., Wierzbicki, C., Webster, H. J., Fisher, C. L., Signell, A. W., Betancor, G., Wilson, H. D., Nebbia, G., Flaviani, F., Cerda, A. C., Merrill, T. V., Wilson, R. E., Cotic, M., Bayzid, N., Thompson, T., Acheson, E., Rushton, S., O'Brien, S., Baker, D. J., Rudder, S., Aydin, A., Sang, F., Debebe, J., Francois, S., Vasylyeva, T. I., Zamudio, M. E., Gutierrez, B., Marchbank, A., Maksimovic, J., Spellman, K., Mccluggage, K., Morgan, M., Beer, R., Afifi, S., Workman, T., Fuller, W., Bresner, C., Angyal, A., Green, L. R., Parsons, P. J., Tucker, R. M., Brown, R., Whiteley, M., Bonfield, J., Puethe, C., Whitwham, A., Liddle, J., Rowe, W., Siveroni, I., Le-Viet, T., Gaskin, A., Johnson, R., Abnizova, I., Ali, M., Allen, L., Anderson, R., Ariani, C., Austin-Guest, S., Bala, S., Bassett, A., Battleday, K., Beal, J., Beale, M., Bellany, S., Bellerby, T., Bellis, K., Berger, D., Berriman, M., Bevan, P., Binley, S., Bishop, J., Blackburn, K., Boughton, N., Bowker, S., Brendler-Spaeth, T., Bronner, I., Brooklyn, T., Buddenborg, S. K., Bush, R., Caetano, C., Cagan, A., Carter, N., Cartwright, J., Monteiro, T. C., Chapman, L., Chillingworth, T. -J., Clapham, P., Clark, R., Clarke, A., Clarke, C., Cole, D., Cook, E., Coppola, M., Cornell, L., Cornwell, C., Corton, C., Crackett, A., Cranage, A., Craven, H., Craw, S., Crawford, M., Cutts, T., Dabrowska, M., Davies, M., Dawson, J., Day, C., Densem, A., Dibling, T., Dockree, C., Dodd, D., Dogga, S., Dougherty, M., Dove, A., Drummond, L., Dudek, M., Durrant, L., Easthope, E., Eckert, S., Ellis, P., Farr, B., Fenton, M., Ferrero, M., Flack, N., Fordham, H., Forsythe, G., Francis, M., Fraser, A., Freeman, A., Galvin, A., Garcia-Casado, M., Gedny, A., Girgis, S., Glover, J., Gould, O., Gray, A., Gray, E., Griffiths, C., Gu, Y., Guerin, F., Hamilton, W., Hanks, H., Harrison, E., Harrott, A., Harry, E., Harvison, J., Heath, P., Hernandez-Koutoucheva, A., Hobbs, R., Holland, D., Holmes, S., Hornett, G., Hough, N., Huckle, L., Hughes-Hallet, L., Hunter, A., Inglis, S., Iqbal, S., Jackson, A., Jackson, D., Verdejo, C. J., Jones, M., Kallepally, K., Kay, K., Keatley, J., Keith, A., King, A., Kitchin, L., Kleanthous, M., Klimekova, M., Korlevic, P., Krasheninnkova, K., Lane, G., Langford, C., Laverack, A., Law, K., Lensing, S., Lewis-Wade, A., Lin, Q., Lindsay, S., Linsdell, S., Long, R., Lovell, J., Mack, J., Maddison, M., Mamun, I., Mansfield, J., Marriott, N., Martin, M., Mayho, M., Mcclintock, J., Mchugh, S., Mcminn, L., Meadows, C., Mobley, E., Moll, R., Morra, M., Morrow, L., Murie, K., Nash, S., Nathwani, C., Naydenova, P., Neaverson, A., Nerou, E., Nicholson, J., Nimz, T., Noell, G. G., O'Meara, S., Ohan, V., Olney, C., Ormond, D., Oszlanczi, A., Pang, Y. F., Pardubska, B., Park, N., Parmar, A., Patel, G., Payne, M., Peacock, S., Petersen, A., Plowman, D., Preston, T., Quail, M., Rance, R., Rawlings, S., Redshaw, N., Reynolds, J., Reynolds, M., Rice, S., Richardson, M., Roberts, C., Robinson, K., Robinson, M., Robinson, D., Rogers, H., Rojo, E. M., Roopra, D., Rose, M., Rudd, L., Sadri, R., Salmon, N., Saul, D., Schwach, F., Seekings, P., Simms, A., Sinnott, M., Sivadasan, S., Siwek, B., Sizer, D., Skeldon, K., Skelton, J., Slater-Tunstill, J., Sloper, L., Smerdon, N., Smith, C., Smith, J., Smith, K., Smith, M., Smith, S., Smith, T., Sneade, L., Soria, C. D., Sousa, C., Souster, E., Sparkes, A., Spencer-Chapman, M., Squares, J., Steed, C., Stickland, T., Still, I., Stratton, M., Strickland, M., Swann, A., Swiatkowska, A., Sycamore, N., Swift, E., Symons, E., Szluha, S., Taluy, E., Tao, N., Taylor, K., Thompson, S., Thompson, M., Thomson, M., Thomson, N., Thurston, S., Toombs, D., Topping, B., Tovar-Corona, J., Ungureanu, D., Uphill, J., Urbanova, J., Van, P. J., Vancollie, V., Voak, P., Walker, D., Walker, M., Waller, M., Ward, G., Weatherhogg, C., Webb, N., Wells, A., Wells, E., Westwood, L., Whipp, T., Whiteley, T., Whitton, G., Widaa, S., Williams, M., Wilson, M., Wright, S., Harvey, W., Virgin, H. W., Lanzavecchia, A., Piccoli, L., Doffinger, R., Wills, M., Veesler, D., Corti, D., and Gupta, R. K.
Subjects: 0301 basic medicine, Male, Models, Molecular, Passive, Antibodies, Viral, Neutralization, 0302 clinical medicine, Models, Monoclonal, 80 and over, Viral, Neutralizing antibody, Neutralizing, Aged, 80 and over, Vaccines, Vaccines, Synthetic, Multidisciplinary, biology, Antibodies, Monoclonal, C500, Middle Aged, C700, Spike Glycoprotein, Vaccination, Spike Glycoprotein, Coronavirus, Female, Angiotensin-Converting Enzyme 2, Antibody, Aged, Antibodies, Neutralizing, COVID-19, COVID-19 Vaccines, HEK293 Cells, Humans, Immune Evasion, Immunization, Passive, Mutation, Neutralization Tests, SARS-CoV-2, medicine.drug_class, B100, Monoclonal antibody, Antibodies, Virus, 03 medical and health sciences, Immune system, medicine, COVID-19 Serotherapy, QR355, Synthetic, Molecular, Virology, Coronavirus, 030104 developmental biology, Immunization, biology.protein, 030217 neurology & neurosurgery
Abstract: Transmission of SARS-CoV-2 is uncontrolled in many parts of the world; control is compounded in some areas by the higher transmission potential of the B.1.1.7 variant1, which has now been reported in 94 countries. It is unclear whether the response of the virus to vaccines against SARS-CoV-2 on the basis of the prototypic strain will be affected by the mutations found in B.1.1.7. Here we assess the immune responses of individuals after vaccination with the mRNA-based vaccine BNT162b22. We measured neutralizing antibody responses after the first and second immunizations using pseudoviruses that expressed the wild-type spike protein or a mutated spike protein that contained the eight amino acid changes found in the B.1.1.7 variant. The sera from individuals who received the vaccine exhibited a broad range of neutralizing titres against the wild-type pseudoviruses that were modestly reduced against the B.1.1.7 variant. This reduction was also evident in sera from some patients who had recovered from COVID-19. Decreased neutralization of the B.1.1.7 variant was also observed for monoclonal antibodies that target the N-terminal domain (9 out of 10) and the receptor-binding motif (5 out of 31), but not for monoclonal antibodies that recognize the receptor-binding domain that bind outside the receptor-binding motif. Introduction of the mutation that encodes the E484K substitution in the B.1.1.7 background to reflect a newly emerged variant of concern (VOC 202102/02) led to a more-substantial loss of neutralizing activity by vaccine-elicited antibodies and monoclonal antibodies (19 out of 31) compared with the loss of neutralizing activity conferred by the mutations in B.1.1.7 alone. The emergence of the E484K substitution in a B.1.1.7 background represents a threat to the efficacy of the BNT162b2 vaccine.
Published: 2021

24. Primitive Quantum Gates for Dihedral Gauge Theories

Author: Alam, M. Sohaib, Hadfield, Stuart, Lamm, Henry, and Li, Andy C. Y.
Subjects: Quantum Physics, High Energy Physics - Phenomenology, High Energy Physics - Lattice, High Energy Physics - Phenomenology (hep-ph), High Energy Physics - Lattice (hep-lat), FOS: Physical sciences, Quantum Physics (quant-ph)
Abstract: We describe the simulation of dihedral gauge theories on digital quantum computers. The nonabelian discrete gauge group $D_N$ -- the dihedral group -- serves as an approximation to $U(1)\times\mathbb{Z}_2$ lattice gauge theory. In order to carry out such a lattice simulation, we detail the construction of efficient quantum circuits to realize basic primitives including the nonabelian Fourier transform over $D_N$, the trace operation, and the group multiplication and inversion operations. For each case the required quantum resources scale linearly or as low-degree polynomials in $n=\log N$. We experimentally benchmark our gates on the Rigetti Aspen-9 quantum processor for the case of $D_4$. The fidelity of all $D_4$ gates was found to exceed $80\%$., Comment: Published version
Published: 2021
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25. Characterization and recognition of handwritten digits using Julia

Author: Jishan, M. A., Alam, M. S., Islam, Afrida, Mazumder, I. R., Mahmud, K. R., and Azad, A. K. Al
Subjects: FOS: Computer and information sciences, Computer Vision and Pattern Recognition (cs.CV), Computer Science - Computer Vision and Pattern Recognition
Abstract: Automatic image and digit recognition is a computationally challenging task for image processing and pattern recognition, requiring an adequate appreciation of the syntactic and semantic importance of the image for the identification ofthe handwritten digits. Image and Pattern Recognition has been identified as one of the driving forces in the research areas because of its shifting of different types of applications, such as safety frameworks, clinical frameworks, diversion, and so on.In this study, for recognition, we implemented a hybrid neural network model that is capable of recognizing the digit of MNISTdataset and achieved a remarkable result. The proposed neural model network can extract features from the image and recognize the features in the layer by layer. To expand, it is so important for the neural network to recognize how the proposed modelcan work in each layer, how it can generate output, and so on. Besides, it also can recognize the auto-encoding system and the variational auto-encoding system of the MNIST dataset. This study will explore those issues that are discussed above, and the explanation for them, and how this phenomenon can be overcome.
Published: 2021
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26. Quantum simulation of $ϕ^4$ theories in qudit systems

Author: Kurkcuoglu, Doga Murat, Alam, M. Sohaib, Job, Joshua Adam, Li, Andy C. Y., Macridin, Alexandru, Perdue, Gabriel N., and Providence, Stephen
Subjects: Computer Science::Hardware Architecture, Computer Science::Emerging Technologies, FOS: Physical sciences, Quantum Physics, Quantum Physics (quant-ph), Hardware_LOGICDESIGN
Abstract: We discuss the implementation of quantum algorithms for lattice $Φ^4$ theory on circuit quantum electrodynamics (cQED) system. The field is represented on qudits in a discretized field amplitude basis. The main advantage of qudit systems is that its multi-level characteristic allows the field interaction to be implemented only with diagonal single-qudit gates. Considering the set of universal gates formed by the single-qudit phase gate and the displacement gate, we address initial state preparation and single-qudit gate synthesis with variational methods., 6 pages, 3 figures
Published: 2021
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27. Nonce@Once: A Single-Trace EM Side Channel Attack on Several Constant-Time Elliptic Curve Implementations in Mobile Platforms

Author: Alam, M., Yilmaz, B., Werner, F., Samwel, N., Zajic, A., Genkin, A., Yarom, D., Prvulovic, M., and Maffei, M.
Published: 2021

28. Improved measurement of the Cabibbo-Kobayashi-Maskawa angle α using B0(B)→p+p- decays

Author: Aubert, Bernard, Abe, T., Abrams, G. S., Adye, T., Ahmed, M., Ahmed, S., Alam, M. S., Albert, J., Aleksan, R., Allen, M.T., Allison, John, Allmendinger, T., Altenburg, D., Andreassen, R., Andreotti, M., Angelini, C., Anulli, F., Arnaud, N., Aston, D., Azzolini, V., Baak, M., Back, J.J., Bailey, S., Baldini-Ferroli, R., Band, H.R., Banerjee, Sw., Barate, R., Bard, D.J., Barlow, N.R., Barlow, R.J., Barrett, M., Bartoldus, R., Batignani, G., Bauer, J.M., Beck, T.W., Behera, P.K., Bellini, F., Benayoun, M., Benelli, G., Berger, N., Berger-Hryn'ova, Tetiana, Bernard, Denis, 1, Berryhill, J.W., Best, D., Bettarini, S., Bettoni, D., Bevan, A.J., Bhimji, W., Bhuyan, B., Bianchi, F., Biasini, M., Biesiada, Jed, Blanc, F., Blaylock, G., Blinov, A.E., Blinov, V.E., Bloom, P., Bomben, M., Bona, Marcella, Bondioli, M., Bonneaud, G.R., Borgland, A.W., Bosisio, L., Boutigny, D., Bowerman, D.A., Boyarski, A.M., Boyd, J.T., Bozzi, C., Brandenburg, G., Brandt, T., Brau, J., Breon, A.B., Briand, H., Brose, J., Brown, C.L., Brown, C.M., Brown, David Nathan, Brown, David Norvil, Bruinsma, M., Brunet, S., Bucci, F., Buchanan, C., Buchmueller, O.L., Bugg, W., Bukin, A.D., Bulten, H., Burchat, P.R., Burke, J.P., Button-Shafer, Janice, Buzzo, A., Cahn, R.N., Calabrese, R., Calcaterra, A., Calderini, G., Campagnari, C., Capra, R., Carpinelli, M., Cartaro, C., Cavallo, N., Cavoto, G., Chaisanguanthum, K.S., Chao, M., Charles, E., Charles, M.J., Chauveau, J., Chavez, C.A., Chen, Anping., Chen, C., Chen, E., Chen, J.C., Chen, S., Chen, X., Cheng, B., Cheng, C.H., Chevalier, N., Christ, S., Cibinetto, G., Clark, P.J., Claus, R., Cochran, J., Colecchia, F., Coleman, J.P., Contri, R., Convery, M.R., Cormack, C.M., Cossutti, F., Cote, D., Cottingham, W.N., Couderc, F., Covarelli, R., Cowan, G., Cowan, R., Crawley, H.B., Cremaldi, L., Cristinziani, M., Cuhadar-Donszelmann, T., Cunha, A., D'Orazio, A., Dahmes, B., Dallapiccola, C., Danielson, N., Dasu, S., Datta, Mousumi, Dauncey, Paul D., David, P., Davier, M., Davis, C.L., Day, C.T., De Groot, N., De Nardo, G., Del Buono, L., Della Ricca, G., Di Lodovico, F., Di Marco, E., Dickopp, M., Dingfelder, J.C., Dittongo, S., Dong, D., Dorfan, J., Dorigo, A., Druzhinin, V.P., Dubitzky, R.S., Dubois-Felsmann, G.P., Dujmic, D., Dunwoodie, W., Dvoretskii, A., Eckhart, E.A., Eckmann, R., Edwards, A.J., Egede, U., Eichenbaum, A.M., Eigen, G., Eisner, A.M., Elmer, P., Emery, S., Ernst, J.A., Eschenburg, V., Eyges, V., Fabozzi, F., Faccini, R., Fan, S., Farbin, A., Feltresi, E., Ferrarotto, F., Ferroni, F., Field, R.C., Finocchiaro, G., Flacco, C.J., Flack, R.L., Flaecher, H.U., Flood, K.T., Ford, K.E., Ford, William T., Forster, I.J., Forti, F., Fortin, D., Foulkes, S.D., Franek, B., Frey, R., Fritsch, M., Fry, J.R., Gabathuler, E., Gaidot, A., Gaillard, J.R., Galeazzi, F., Gallo, F., Gamba, D., Gamet, R., Gan, K.K., Ganzhur, S.F., Gary, J.W., Gaspero, Mario, Gatto, C., George, K.A., Gill, M.S., Giorgi, M.A., Giraud, P.F., Giroux, X., Gladney, L., Glanzman, T., Godang, R., Goetzen, K., Golubev, V.B., Gopal, G.P., Gough Eschrich, Ivo M., Gowdy, S.J., Gradl, W., Graham, M., Grancagnolo, S., Grauges Pous, Eugeni, Graziani, G., Green, M.G., Greene, M.G., Grenier, Gerald Jean, Grenier, P., Gritsan, A.V., Grosdidier, G., Groysman, Y., Guo, Q.H., Hadavand, H.K., Hadig, T., Haire, M., Halyo, V., Hamano, K., Hamel de Monchenault, G., Hamon, O., Harrison, P.F., Harrison, T.J., Hart, A.J., Hartfiel, Brandon L., Harton, J.L., Hast, C., Hauke, A., Hawkes, C.M., Hearty, C., Held, T., Hertzbach, Stanley S., Heusch, C.A., Hill, E.J., Hitlin, D.G., Hocker, Andreas, Hodgkinson, Mark C., Hollar, J.J., Hong, T.M., Honscheid, K., Hufnagel, D., Hulsbergen, W.D., Hutchcroft, D.E., Igonkina, O., Innes, Walter R., Ivanchenko, V.N., Izen, J.M., Jackson, P.D., Jackson, P.S., Jacobsen, R.G., Jawahery, A., Jayatilleke, S., Jessop, C.P., John, M.J.J., Johnson, J.R., Judd, D., Kadel, R.W., Kadyk, J., Kagan, H., Karyotakis, Y., Kass, R., Kazuhito, S., Kelly, M.P., Kelsey, M.H., Kerth, L.T., Khan, A., Kim, H., Kim, P., Kirkby, David P., Kitayama, I., Klose, V., Knecht, N.S., Koch, H., Kocian, M.L., Koeneke, K., Kofler, R., Kolomensky, Yu.G., Koptchev, V.B., Kovalskyi, D., Kowalewski, Robert V., Kozanecki, W., Kravchenko, E.A., Krishnamurthy, M., Kroeger, R., Kroseberg, J., Kukartsev, G., Kutter, P.E., Kyberd, P., Lacker, H.M., Lae, C.K., Lafferty, G.D., Lanceri, L., Lange, D.J., Langenegger, Urs, Lankford, A.J., Latham, T.E., Lau, Y.P., Lazzaro, A., Le Diberder, F., Lees, J.P., Legendre, M., Leith, D.W.G.S., Lepeltier, V., Leruste, Ph., Lewandowski, B., Li Gioi, L., Li, H., Libby, J., Lillard, V., Lista, L., Liu, R., Lo Vetere, M., LoSecco, J.M., Lockman, W.S., Lombardo, V., London, G.W., Long, O., Lou, X.C., Lu, A., Lu, C., Lu, M., Luitz, S., Luppi, E., Lusiani, A., Luth, V., Lutz, A.M., Lynch, G., Lynch, H.L., MacFarlane, D.B., Macri, M., Majewski, S.A., Malcles, J., Mallik, U., Maly, E., Mancinelli, G., Mandelkern, M., Marchiori, G., Margoni, M., Marks, J., Marsiske, H., Martinez-Vidal, F., Mattison, T.S., Mayer, B., Mazur, M.A., Mazzoni, M.A., McKenna, J.A., McMahon, T.R., Meadows, B.T., Mellado, B., Messner, R., Meyer, W.T., Mihalyi, A., Mir, L.M., Mohanty, G.B., Mohapatra, A.K., Mommsen, R.K., Monge, M.R., Monorchio, D., Moore, T.B., Morandin, M., Morgan, S.E., Morganti, M., Morganti, Silvio, Morii, M., Morton, G.W., Muheim, F., Muller, D.R., Naisbit, M.T., Narsky, Ilya V., Nash, J.A., Nauenberg, U., Neal, H., Negrini, M., Neri, N., Nesom, G., Nicholson, H., Nikolich, M.B., Nogowski, R., O'Grady, C.P., Ocariz, J., Oddone, P.J., Ofte, I., Olaiya, E.O., Olivas, A., Olsen, J., Onuchin, A.P., Orimoto, T.J., Otto, S., Ozcan, V.E., Paar, H.P., Paick, K., Palano, A., Palombo, F., Pan, Y., Panetta, J., Panvini, R.S., Paoloni, E., Paolucci, P., Pappagallo, M., Parry, R.J., Passaggio, S., Patel, P.M., Patrignani, C., Patteri, P., Payne, D.J., Pelizaeus, M., Perazzo, A., Perl, M., Peruzzi, I.M., Peters, K., Petersen, B.A., Petersen, T.C., Petzold, A., Piatenko, T., Piccolo, D., Piccolo, M., Piemontese, L., Pierini, Maurizio, Pioppi, M., Piredda, G., Plaszczynski, S., Playfer, S., Poireau, V., Polci, F., Pompili, A., Poropat, P., Porter, F.C., Posocco, M., Potter, C.T., Prell, S., Prepost, R., Pripstein, M., Pulliam, T., Purohit, M.V., Qi, N.D., Rahatlou, S., Rahimi, A.M., Rama, M., Rankin, P., Ratcliff, B.N., Raven, G., Reidy, J., Ricciardi, S., Richman, J.D., Ritchie, J.L., Rizzo, G., Roat, C., Roberts, D.A., Robertson, S.H., Robutti, E., Rodier, S., Roe, N.A., Roethel, W., Ronan, M.T., Roney, J.M., Rong, G., Roodman, A., Roos, L., Rosenberg, E.I., Rotondo, M., Roudeau, P., Rubin, A.E., Ruddick, W.O., Ryd, A., Saeed, M.A., Safai Tehrani, F., Saleem, M., Salnikov, A.A., Salvatore, F., Samuel, A., Sanders, D.A., Santroni, A., Saremi, S., Sarti, A., Satpathy, A., Schalk, T., Schenk, S., Schindler, R.H., Schott, G., Schrenk, S., Schroder, H., Schroeder, T., Schubert, J., Schubert, Klaus R., Schumm, B.A., Schune, M.H., Schwiening, J., Schwierz, R., Schwitters, R.F., Sciacca, C., Sciolla, G., Seiden, A., Sekula, S.J., Serednyakov, S.I., Sharma, V., Shen, B.C., Simani, M.C., Simi, G., Simonetto, F., Sinev, N.B., Skovpen, Yu.I., Smith, A.J.S., Smith, James G., Snoek, H.L., Snyder, A., Sobie, R.J., Soffer, A., Soha, A., Sokoloff, M.D., Solodov, E.P., Spaan, B., Spanier, S.M., Spradlin, Patrick Michael, Staengle, H., Steinke, M., Stelzer, J., Stocchi, A., Stoker, D.P., Stroili, R., Strom, David M., Strube, J., Stugu, B., Su, D., Sullivan, M.K., Summers, D.J., Sundermann, J.E., Tan, P., Taras, P., Taylor, F., Taylor, G.P., Telnov, A.V., Teodorescu, L., Ter-Antonyan, R., Therin, G., Thiebaux, Ch., Thiessen, D., Thompson, J.M., Tisserand, V., Toki, W.H., Torrence, E., Tosi, S., Touramanis, C., Ulmer, K.A., Uwer, U., Va'vra, J., Vasileiadis, G., Vasseur, G., Verderi, M., Verkerke, W., Viaud, B., Vitale, L., Voci, C., Voena, C., Vuagnin, G., Wagner, G., Wagner, S.R., Wagoner, D.E., Waldi, R., Walsh, J., Wang, K., Wang, P., Wappler, F.R., Watson, A.T., Weaver, M., Weidemann, A.W., Weinstein, A.J.R., Wenzel, W.A., Wilden, L., Williams, D.C., Williams, J.C., Willocq, S., Wilson, F.F., Wilson, J.R., Wilson, M.G., Wilson, R.J., Wisniewski, William J., Wittgen, M., Won, E., Wong, Q.K., Wormser, G., Wright, D.H., Wright, D.M., Wu, J., Wu, S.L., Xie, Y., Yamamoto, R.K., Yang, S., Yarritu, A.K., Ye, S., Yeche, Ch., Yi, J., Young, C.C., Yu, Z., Yumiceva, F.X., Yushkov, A.N., Zallo, A., Zeng, Q., Zghiche, A., Zhang, J., Zhang, L., Zhao, H.W., Zhu, Y.S., Zito, M., de Sangro, R., de la Vaissiere, Ch., del Re, D., von Wimmersperg-Toeller, J.H., BaBar Collaboration, and American Physical Society
Subjects: Upsilon(10570), Pair production, Electroproduction, CKM matrix, Isospin, Colliding beams, Hadronic decay, Annihilation, Electron positron
Abstract: We present results from an analysis of B0(B¯¯¯0)→ρ+ρ− using 232×106 Υ(4S)→BB¯¯¯ decays collected with the BABAR detector at the PEP-II asymmetric-energy B factory at SLAC. We measure the longitudinal polarization fraction fL=0.978±0.014(stat)+0.021−0.029(syst) and the CP-violating parameters SL=−0.33±0.24(stat)+0.08−0.14(syst) and CL=−0.03±0.18(stat)±0.09(syst). Using an isospin analysis of B→ρρ decays, we determine the unitarity triangle parameter α. The solution compatible with the standard model is α=(100±13)°.
Published: 2021

29. Study of resonances in exotic drip-line nuclei by the use of super-symmetric quantum mechanics

Author: Khan, Md. A., Hasan, M., Mondal, S. H., Alam, M., and Surungan, T.
Subjects: Nuclear Theory (nucl-th), Nuclear Theory, FOS: Physical sciences
Abstract: In this paper, a nice theoretical scheme is presented to investigate resonant and bound states in weakly bound nuclear systems by the use of isospectral potentials together with hyperspherical harmonics expansion. In this scheme, a new potential is constructed which is strictly isospectral with the original shallow potential and has properties that are desirable to calculate resonances more accurately and elegantly. The effectiveness of the method has been checked in terms of its application to the $0^+$ resonances in the neutron-rich isotopes $^{18,20}$C in the two-neutron plus core three-body cluster model. The results are in excellent agreement with the available data., Comment: 18 pages, 12 figures, 5 tables. arXiv admin note: substantial text overlap with arXiv:2010.01585
Published: 2021
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30. Regulatory and Institutional Framework for the Conservation of Coral Reefs in Bangladesh: A Critical Review

Author: Rahman Md Mizanur and Aslam, Alam M
Subjects: Anthropogenic, Disturbances, Stressors, Management, Tourism, Coordination
Abstract: The coral reefs' crisis is increasing, with the combined effects of natural and anthropogenic disturbances. It is predicted that coral reefs could extinct soon from the world. Bangladesh has only one coral Island named Saint Martin, locally known as 'Narikel Jinjira'. This is one of the most popular tourist spots in Bangladesh, entertaining thousands of tourists per year due to its unique landscape, blue water, and coral colonies' presence. This Island lost most of the coral in recent times. The coral reef ecosystem management needs to focus on the reformation of the legal and institutional frameworks for enhancing the local administration's capabilities to address the adverse effects of the stressors and promote the ecosystem services by improving the resilience. The study aims at analysing the existing institutional and legal frameworks for conserving the coral reefs. To collect data, fieldwork was conducted at Saint Martin Island and Teknaf Upazila. The related literature on legal documents was reviewed critically. It is found that despite having legal mechanisms and institutional frameworks, non-compliances with laws and poor coordination among different sectors are widespread, resulting in severe degradation of coral resources. In most of the laws, robust institutional arrangements were ignored. The study recommends integrating the legal and institutional frameworks governing the environment, tourism, and fisheries sectors. Effective marine governance, increasing coordination among different sectors, amending some existing rules, and activating MCS (monitoring, control, surveillance) system can improve the scenario.
Published: 2020
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31. Are the patients with drug sensitive tuberculosis screened for ocular manifestations? A five year analysis from a medical college hospital of Karnataka, India

Author: Vidya Hegde, Tabia Mir, Akshaya Kibballi Madhukeshwar, Rashmi Shambhu, and Parvez Alam M. Tank
Subjects: Drug, Pediatrics, medicine.medical_specialty, Tuberculosis, genetic structures, Referral, media_common.quotation_subject, Antitubercular Agents, India, Tuberculosis, Ocular, Asymptomatic, Optic neuropathy, 03 medical and health sciences, medicine, Humans, Adverse effect, Ethambutol, media_common, 0303 health sciences, 030306 microbiology, business.industry, medicine.disease, eye diseases, Hospitals, Infectious Diseases, Pharmaceutical Preparations, medicine.symptom, business, Uveitis, medicine.drug
Abstract: Background Early diagnosis and prompt treatment may be sight-saving in patients with Ocular Tuberculosis (TB). Patients on anti tubercular treatment (ATT) also need ophthalmological examination at the start of the treatment and monitoring for toxic optic neuropathy regularly till the completion of treatment. This study is a situation analysis of the referral rates to ophthalmologist and clinical presentations of ocular TB among patients admitted with drug sensitive tuberculosis (DS TB). Methods A five year record analysis (2013–2017) of patients admitted with DS TB in a medical college hospital setting was done. Demographic and clinical presentations of the patients were recorded. The details about the referral, clinical findings, any possible risk associated with ocular TB and ocular side effects of ATT were noted. Data was entered in Microsoft excel and analysed for descriptive statistics. Results Among 225 inpatients, only 72 (32%) patients were referred to ophthalmologist. The referral rates increased over the period of five years. Intra ocular TB was diagnosed among 11 (15.3%) patients. Only 5 patients among these had complained of reduced vision and others were asymptomatic. Conclusion The referral of DS TB patients to ophthalmologist was sub optimal. All the DSTB cases need ophthalmic evaluation keeping in mind the possibility of ocular TB and also the adverse effects of ATT.
Published: 2020

32. CFD Evaluation of Experimental Measurements of Oscillating Mist Fan Cooling in a Large Indoor Space

Author: Farnham, C., JIHUI YUAN, Emura, K., Alam, M. A., and Mizuno, T.
Published: 2020

33. Hyperspherical few-body model calculation for cascade $��$ exotic hypernuclei with reference to nuclear drip lines

Author: Khan, Md. A., Alam, M., Hasan, M., and Mondal, S. H.
Subjects: Nuclear Theory (nucl-th), Nuclear Theory, FOS: Physical sciences, High Energy Physics::Experiment, Nuclear Experiment
Abstract: In this paper, we presented the ground state energies calculated for some single and double cascade hyperon($��^{-}$) hypernuclei. For hypernuclei of the type $_��^{A_c+1}$X we applied $��+^A_c$X two-body model and for hypernuclei of the type $_{��}^{A_c+2}$X we adopted $��+��+^A_c$X three-body model. A two-term Gaussian (Isle type) potential with adjustable parameters is chosen as the $��$-nucleus interaction, while a two-term Yukawa-type potential has been chosen for the $��$ pair. In the three-body model calculation, we adopted the hyperspherical harmonics expansion (HHE) formalism. The resulting two- and three-body Schr{��}dinger equations subject to appropriate boundary condition's have been solved numerically to get the ground-state energies and wavefunctions. Computed values are in excellent agreement with the observed ones as found in the literature. Analysis of the calculated observables indicates that the hyperons stay close to the core-nucleus. Hypernuclei formed as a result of absorption of one or more $��$-hyperon(s) by a normal nucleus (bound or unbound) are found to have more stability than those formed as a result of absorption of one or more $��$ hyperon(s) by the same nucleus. This fact flashes towards the possibility of the existence of a valley of strange hypernuclei near the drip lines., 15 pages, 7 figures
Published: 2020
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34. On modifications of fundamental radiative processes in near-zero-index media of various dimensions

Author: Michaël, Lobet, Liberal, Iñigo, Knall, Erik N., Alam, M. Zahirul, Reshef, Orad, Boyd, Robert W., Engheta, Nader, and Mazur, Eric
Subjects: FOS: Physical sciences, Physics - Optics, Optics (physics.optics)
Abstract: Spontaneous emission, stimulated emission and absorption are the three fundamental radiative processes describing light-matter interactions. Here, we theoretically study the behaviour of these fundamental processes inside an unbounded medium exhibiting a vanishingly small refractive index, i.e., a near-zero-index (NZI) host medium. We present a generalized framework to study these processes and find that the spatial dimension of the NZI medium has profound effects on the nature of the fundamental radiative processes. Our formalism highlights the role of the number of available optical modes as well as the ability of an emitter to couple to these modes as a function of the dimension and the class of NZI media. We demonstrate that the fundamental radiative processes are inhibited in 3D homogeneous lossless zero index materials but may be strongly enhanced in a zero index medium of reduced dimensionality. Our findings have implications in thermal, nonlinear and quantum optics as well as in designing quantum metamaterials at optical or microwave frequencies.
Published: 2020
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35. Adapting care for older cancer patients during the COVID-19 pandemic: Recommendations from the International Society of Geriatric Oncology (SIOG) COVID-19 Working Group

Author: Battisti NML, Mislang AR, Cooper L, O'Donovan A, Audisio RA, Cheung KL, Sarrió RG, Stauder R, Soto-Perez-de-Celis E, Jaklitsch M, Williams GR, O'Hanlon S, Alam M, Cairo C, Colloca G, Gil LA, Sattar S, Kantilal K, Russo C, Lichtman SM, Brain E, Kanesvaran R, and Wildiers H
Subjects: COVID-19, Competing risks, Geriatric oncology, Older patients, Recommendations, SARS-CoV-2
Abstract: The COVID-19 pandemic poses a barrier to equal and evidence-based management of cancer in older adults. The International Society of Geriatric Oncology (SIOG) formed a panel of experts to develop consensus recommendations on the implications of the pandemic on several aspects of cancer care in this age group including geriatric assessment (GA), surgery, radiotherapy, systemic treatment, palliative care and research. Age and cancer diagnosis are significant predictors of adverse outcomes of the COVID-19 infection. In this setting, GA is particularly valuable to drive decision-making. GA may aid estimating physiologic reserve and adaptive capability, assessing risk-benefits of either providing or temporarily withholding treatments, and determining patient preferences to help inform treatment decisions. In a resource-constrained setting, geriatric screening tools may be administered remotely to identify patients requiring comprehensive GA. Tele-health is also crucial to ensure adequate continuity of care and minimize the risk of infection exposure. In general, therapeutic decisions should favor the most effective and least invasive approach with the lowest risk of adverse outcomes. In selected cases, this might require deferring or omitting surgery, radiotherapy or systemic treatments especially where benefits are marginal and alternative safe therapeutic options are available. Ongoing research is necessary to expand knowledge of the management of cancer in older adults. However, the pandemic presents a significant barrier and efforts should be made to ensure equitable access to clinical trials and prospective data collection to elucidate the outcomes of COVID-19 in this population.
Published: 2020

36. Precision measurement of the ${\cal B}(��(3S)\to��^+��^-)/{\cal B}(��(3S)\to��^+��^-)$ ratio

Author: Lees, J. P., Poireau, V., Tisserand, V., Grauges, E., Palano, A., Eigen, G., Brown, D. N., Kolomensky, Yu. G., Fritsch, M., Koch, H., Schroeder, T., Cheaib, R., Hearty, C., Mattison, T. S., McKenna, J. A., So, R. Y., Blinov, V. E., Buzykaev, A. R., Druzhinin, V. P., Golubev, V. B., Kozyrev, E. A., Kravchenko, E. A., Onuchin, A. P., Serednyakov, S. I., Skovpen, Yu. I., Solodov, E. P., Todyshev, K. Yu., Lankford, A. J., Dey, B., Gary, J. W., Long, O., Eisner, A. M., Lockman, W. S., Vazquez, W. Panduro, Chao, D. S., Cheng, C. H., Echenard, B., Flood, K. T., Hitlin, D. G., Kim, J., Li, Y., Lin, D. X., Miyashita, T. S., Ongmongkolkul, P., Oyang, J., Porter, F. C., R��hrken, M., Huard, Z., Meadows, B. T., Pushpawela, B. G., Sokoloff, M. D., Sun, L., Smith, J. G., Wagner, S. R., Bernard, D., Verderi, M., Bettoni, D., Bozzi, C., Calabrese, R., Cibinetto, G., Fioravanti, E., Garzia, I., Luppi, E., Santoro, V., Calcaterra, A., de Sangro, R., Finocchiaro, G., Martellotti, S., Patteri, P., Peruzzi, I. M., Piccolo, M., Rotondo, M., Zallo, A., Passaggio, S., Patrignani, C., Shuve, B. J., Lacker, H. M., Bhuyan, B., Mallik, U., Chen, C., Cochran, J., Prell, S., Gritsan, A. V., Arnaud, N., Davier, M., Diberder, F. Le, Lutz, A. M., Wormser, G., Lange, D. J., Wright, D. M., Coleman, J. P., Gabathuler, E., Hutchcroft, D. E., Payne, D. J., Touramanis, C., Bevan, A. J., Di Lodovico, F., Sacco, R., Cowan, G., Banerjee, Sw., Davis, C. L., Denig, A. G., Gradl, W., Griessinger, K., Hafner, A., Schubert, K. R., Barlow, R. J., Lafferty, G. D., Cenci, R., Jawahery, A., Roberts, D. A., Cowan, R., Robertson, S. H., Seddon, R. M., Neri, N., Palombo, F., Cremaldi, L., Godang, R., Summers, D. J., Taras, P., De Nardo, G., Sciacca, C., Raven, G., Jessop, C. P., LoSecco, J. M., Honscheid, K., Kass, R., Gaz, A., Margoni, M., Posocco, M., Simi, G., Simonetto, F., Stroili, R., Akar, S., Ben-Haim, E., Bomben, M., Bonneaud, G. R., Calderini, G., Chauveau, J., Marchiori, G., Ocariz, J., Biasini, M., Manoni, E., Rossi, A., Batignani, G., Bettarini, S., Carpinelli, M., Casarosa, G., Chrzaszcz, M., Forti, F., Giorgi, M. A., Lusiani, A., Oberhof, B., Paoloni, E., Rama, M., Rizzo, G., Walsh, J. J., Zani, L., Smith, A. J. S., Anulli, F., Faccini, R., Ferrarotto, F., Ferroni, F., Pilloni, A., Piredda, G., B��nger, C., Dittrich, S., Gr��nberg, O., He��, M., Leddig, T., Vo��, C., Waldi, R., Adye, T., Wilson, F. F., Emery, S., Vasseur, G., Aston, D., Cartaro, C., Convery, M. R., Dorfan, J., Dunwoodie, W., Ebert, M., Field, R. C., Fulsom, B. G., Graham, M. T., Hast, C., Innes, W. R., Kim, P., Leith, D. W. G. S., Luitz, S., MacFarlane, D. B., Muller, D. R., Neal, H., Ratcliff, B. N., Roodman, A., Sullivan, M. K., Va'vra, J., Wisniewski, W. J., Purohit, M. V., Wilson, J. R., Randle-Conde, A., Sekula, S. J., Ahmed, H., Bellis, M., Burchat, P. R., Puccio, E. M. T., Alam, M. S., Ernst, J. A., Gorodeisky, R., Guttman, N., Peimer, D. R., Soffer, A., Spanier, S. M., Ritchie, J. L., Schwitters, R. F., Izen, J. M., Lou, X. C., Bianchi, F., De Mori, F., Filippi, A., Gamba, D., Lanceri, L., Vitale, L., Martinez-Vidal, F., Oyanguren, A., Albert, J., Beaulieu, A., Bernlochner, F. U., King, G. J., Kowalewski, R., Lueck, T., Nugent, I. M., Roney, J. M., Sibidanov, A., Sobie, R. J., Tasneem, N., Gershon, T. J., Harrison, P. F., Latham, T. E., Prepost, R., and Wu, S. L.
Subjects: High Energy Physics - Experiment (hep-ex), FOS: Physical sciences, High Energy Physics::Experiment
Abstract: We report on a precision measurement of the ratio ${\cal R}_{��}^{��(3S)} = {\cal B}(��(3S)\to��^+��^-)/{\cal B}(��(3S)\to��^+��^-)$ using data collected with the BaBar detector at the SLAC PEP-II $e^+e^-$ collider. The measurement is based on a 28 fb$^{-1}$ data sample collected at a center-of-mass energy of 10.355 GeV corresponding to a sample of 122 million $��(3S)$ mesons. The ratio is measured to be ${\cal R}_{��}^{��(3S)} = 0.966 \pm 0.008_\mathrm{stat} \pm 0.014_\mathrm{syst}$ and is in agreement with the Standard Model prediction of 0.9948 within 2 standard deviations. The uncertainty in ${\cal R}_{��}^{��(3S)}$ is almost an order of magnitude smaller than the only previous measurement., 8 pages, 4 figures, 3 tables
Published: 2020
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37. Regulatory and Institutional Framework for the Conservation of Coral Reefs in Bangladesh: A Critical Review

Author: Rahman, Md Mizanur and Alam, M
Subjects: geography.geographical_feature_category, Coral, media_common.quotation_subject, Corporate governance, Life Sciences, FOS: Law, Coral reef, Natural (archaeology), Education, Ecosystem services, Geography, Ecosystem management, Psychological resilience, Law, Anthropogenic, Disturbances, Stressors, Management, Tourism, Coordination, Environmental planning, Tourism, media_common
Abstract: The coral reefs' crisis is increasing, with the combined effects of natural and anthropogenic disturbances. It is predicted that coral reefs could extinct soon from the world. Bangladesh has only one coral Island named Saint Martin, locally known as 'Narikel Jinjira'. This is one of the most popular tourist spots in Bangladesh, entertaining thousands of tourists per year due to its unique landscape, blue water, and coral colonies' presence. This Island lost most of the coral in recent times. The coral reef ecosystem management needs to focus on the reformation of the legal and institutional frameworks for enhancing the local administration's capabilities to address the adverse effects of the stressors and promote the ecosystem services by improving the resilience. The study aims at analysing the existing institutional and legal frameworks for conserving the coral reefs. To collect data, fieldwork was conducted at Saint Martin Island and Teknaf Upazila. The related literature on legal documents was reviewed critically. It is found that despite having legal mechanisms and institutional frameworks, non-compliances with laws and poor coordination among different sectors are widespread, resulting in severe degradation of coral resources. In most of the laws, robust institutional arrangements were ignored. The study recommends integrating the legal and institutional frameworks governing the environment, tourism, and fisheries sectors. Effective marine governance, increasing coordination among different sectors, amending some existing rules, and activating MCS (monitoring, control, surveillance) system can improve the scenario.
Published: 2020

38. Search for lepton-flavor violating decays $D^{0}\rightarrow X^{0}e^{\pm}��^{\mp}$

Author: BaBar Collaboration, Lees, J. P., Poireau, V., Tisserand, V., Grauges, E., Palano, A., Eigen, G., Brown, D. N., Kolomensky, Yu. G., Fritsch, M., Koch, H., Schroeder, T., Cheaib, R., Hearty, C., Mattison, T. S., McKenna, J. A., So, R. Y., Blinov, V. E., Buzykaev, A. R., Druzhinin, V. P., Golubev, V. B., Kozyrev, E. A., Kravchenko, E. A., Onuchin, A. P., Serednyakov, S. I., Skovpen, Yu. I., Solodov, E. P., Todyshev, K. Yu., Lankford, A. J., Dey, B., Gary, J. W., Long, O., Eisner, A. M., Lockman, W. S., Panduro, W., Chao, D. S., Cheng, C. H., Echenard, B., Flood, K. T., Hitlin, D. G., Kim, J., Li, Y., Lin, D. X., Miyashita, T. S., Ongmongkolkul, P., Oyang, J., Porter, F. C., R, M., Huard, Z., Meadows, B. T., Pushpawela, B. G., Sokoloff, M. D., Sun, L., Smith, J. G., Wagner, S. R., Bernard, D., Verderi, M., Bettoni, D., Bozzi, C., Calabrese, R., Cibinetto, G., Fioravanti, E., Garzia, I., Luppi, E., Santoro, V., Calcaterra, A., de Sangro, R., Finocchiaro, G., Martellotti, S., Patteri, P., Peruzzi, I. M., Piccolo, M., Rotondo, M., Zallo, A., Passaggio, S., Patrignani, C., Shuve, B. J., Lacker, H. M., Bhuyan, B., Mallik, U., Chen, C., Cochran, J., Prell, S., Gritsan, A. V., Arnaud, N., Davier, M., Diberder, F. Le, Lutz, A. M., Wormser, G., Lange, D. J., Wright, D. M., Coleman, J. P., Gabathuler, E., Hutchcroft, D. E., Payne, D. J., Touramanis, C., Bevan, A. J., Di Lodovico, F., Sacco, R., Cowan, G., Banerjee, Sw., Davis, C. L., Denig, A. G., Gradl, W., Griessinger, K., Hafner, A., Schubert, K. R., Barlow, R. J., Lafferty, G. D., Cenci, R., Jawahery, A., Roberts, D. A., Cowan, R., Robertson, S. H., Seddon, R. M., Neri, N., Palombo, F., Cremaldi, L., Godang, R., Summers, D. J., Taras, P., De, G., Sciacca, C., Raven, G., Jessop, C. P., LoSecco, J. M., Honscheid, K., Kass, R., Gaz, A., Margoni, M., Posocco, M., Simi, G., Simonetto, F., Stroili, R., Akar, S., Ben, E., Bomben, M., Bonneaud, G. R., Calderini, G., Chauveau, J., Marchiori, G., Ocariz, J., Biasini, M., Manoni, E., Rossi, A., Batignani, G., Bettarini, S., Carpinelli, M., Casarosa, G., Chrzaszcz, M., Forti, F., Giorgi, M. A., Lusiani, A., Oberhof, B., Paoloni, E., Rama, M., Rizzo, G., Walsh, J. J., Zani, L., Smith, A. J. S., Anulli, F., Faccini, R., Ferrarotto, F., Ferroni, F., Pilloni, A., Piredda, G., B, C., Dittrich, S., Gr, O., He, M., Leddig, T., Vo, C., Waldi, R., Adye, T., Wilson, F. F., Emery, S., Vasseur, G., Aston, D., Cartaro, C., Convery, M. R., Dorfan, J., Dunwoodie, W., Ebert, M., Field, R. C., Fulsom, B. G., Graham, M. T., Hast, C., Innes, W. R., Kim, P., Leith, D. W. G. S., Luitz, S., MacFarlane, D. B., Muller, D. R., Neal, H., Ratcliff, B. N., Roodman, A., Sullivan, M. K., Va, J., Wisniewski, W. J., Purohit, M. V., Wilson, J. R., Randle, A., Sekula, S. J., Ahmed, H., Bellis, M., Burchat, P. R., Puccio, E. M. T., Alam, M. S., Ernst, J. A., Gorodeisky, R., Guttman, N., Peimer, D. R., Soffer, A., Spanier, S. M., Ritchie, J. L., Schwitters, R. F., Izen, J. M., Lou, X. C., Bianchi, F., De, F., Filippi, A., Gamba, D., Lanceri, L., Vitale, L., Martinez, F., Oyanguren, A., Albert, J., Beaulieu, A., Bernlochner, F. U., King, G. J., Kowalewski, R., Lueck, T., Nugent, I. M., Roney, J. M., Sobie, R. J., Tasneem, N., Gershon, T. J., Harrison, P. F., Latham, T. E., Prepost, R., and Wu, S. L.
Subjects: High Energy Physics - Experiment (hep-ex), FOS: Physical sciences
Abstract: We present a search for seven lepton-flavor-violating neutral charm decays of the type $D^{0}\rightarrow X^{0} e^{\pm} ��^{\mp}$, where $X^{0}$ represents a $��^{0}$, $K^{0}_{\rm S}$, $\bar{K^{*0}}$, $��^{0}$, $��$, $��$, or $��$ meson. The analysis is based on $468$ fb$^{-1}$ of $e^+e^-$ annihilation data collected at or close to the $��(4S)$ resonance with the BaBar detector at the SLAC National Accelerator Laboratory. No significant signals are observed, and we establish 90\% confidence level upper limits on the branching fractions in the range $(5.0 - 22.5)\times 10^{-7}$. The limits are between one and two orders of magnitude more stringent than previous measurements., 12 pages, 2 figures, to be submitted to Physical Review D. arXiv admin note: text overlap with arXiv:1905.00608
Published: 2020
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39. EVALUATION OF PILOT PROJECTS IN THE MINISTRY OF STATE FOR ENVIRONMENTAL AFFAIRS AND ITS RELATIONSHIP TO SUSTAINABLE DEVELOPMENT IN EGYPT GOAL 12: ENSURE QUALITY AND SUSTAINABLE CONSUMPTION AND PRODUCTION PATTERNS

Author: Mandour A. F., Alam M. M. M. A., and Eid M. M. I.
Subjects: Sustainable development, business.industry, Sustainability, Public sector, Sustainable consumption, Cleaner production, Business, Private sector, Environmental planning, State of the Environment, Green economy
Abstract: The aim of the study is to identify the successful models for the sustainability of internationally funded pilot projects and to achieve their objectives in the industrial pollution control project Phase II, The extent of the legal obligation of the establishment to environmental legislation and the setting of environmental objectives as a general framework for the activity of industrial enterprises, As well as studying the impact of the concepts of environmental economics (green) as a main input to achieve sustainable development among those concerned with industry in Egypt. The descriptive syllabus was utilized thanks to its dependence on describing the phenomenon and extracting the results through gathering the statements and information necessary for research. Data were gathered from the Ministry of State for Environmental Affairs, reports of donor countries and state of the environment reports issued by the Ministry of State for Environmental Affairs About Egyptian Pollution Abatement Project (EPAP) between 2007 and 2015. (Case Study of Industrial Pollution Control (End of Tube) (Air) Project for a number of cement production projects and a number of brick production factories in Arab Abu Sa'ed area and rehabilitation of phosphoric plant Abu Zaabal Fertilizer and Chemical Factory). The results have resulted in the adjustment of the environmental conditions of the industrial enterprises and the support of the cleaner production projects. These environmental projects contribute to reducing the use of raw materials and reducing the resulting waste, thereby reducing the cost of production, thus achieving the economic and environmental dimensions and their commitment to the social dimension of the workers inside and outside the plant. In highly polluted areas and thus improve the conditions of the local environment by encouraging private sector companies and the public sector to invest in the field of pollution control and support the applications of appropriate binding methods and inspection activities to Knapp technical capacity development within environmental institutions and the participating banks and to improve environmental awareness and performance in Egypt with a focus on the Greater Cairo and Alexandria and the strengthening of the special commitment to environmental protection law 4 of 1994, as amended, environmental authorities capabilities. But the information collected by the researcher indicates that many of these projects will be affected by the absence of international funding for the inability of companies alone or the insufficient budget allocated by the State to reduce pollution, which will be clear from the implementation of the plan of this study. The researchers recommended the activation of the law of environmental protection 4 of 1994 and its amendments to sustain the results of the pilot projects through the support of the environmental inspection of the EEAA with a number of human cadres while providing the potential to increase the inspection rates on the industrial zones to maintain the sustainability of the industrial pollution control project, Green economy and cleaner production mechanism in Egyptian industry, also an alternative to foreign grants and loans should be found in financing environmental projects and providing technical and institutional support and maintaining their sustainability through the establishment of a national fund for financing environmental projects. It should establish national banks, the Ministry of State for Environmental Affairs, the Ministry of Finance, Export Development Fund), Ministry of Investment, Social Fund for Development, provided that projects are financed with interest determined by the Central Bank of Egypt.
Published: 2018

40. GUL-E- SURKH (Rosa damascena Mill.) AND ITS THERAPEUTIC USES DESCRIBED IN UNANI LITERATURE

Author: Najeeb Jahan, Wadud Abdul, Mehar Adiba, Aisha Perveen, Nazamuddin, Asim Mohammad Khan, and Tanwir Alam M
Subjects: Rosa × damascena, biology, Traditional medicine, food and beverages, Mill, General Medicine, biology.organism_classification, Mathematics
Abstract: Gul-e-Surkh (Rose flower) is the Persian name for the Rosa damascena Mill. In Unani system of medicine Rose flower is used for medicinal purposes. Ibn Sina considers Gul-e- Surkh as one of the best drug for liver. Rose flower in various doses form and/or in combination with many other drugs are indicated in various disease. It is commonly being used as general tonic for Lungs, Stomach, Intestine, Liver, Rectum, Kidney, Heart, and Uterus. Fresh flowers are purgative and dried one is astringent in properties. In this review article authors try to encompass the therapeutic indication of Rosa damascena Mill described in Unani literature.
Published: 2018

41. 1052. Characterisation of the DNA binding properties of ridinilazole, a selective antibiotic currently in phase III trials for the treatment of Clostridioides difficile

Author: Mason, Clive, Avis, Tim, Coward, Chris, Powell, David, Duperchy, Esther, Hu, Chenlin, Jahangir Alam, M, Begum, Khurshida, Garey, Kevin W, Reich, Stefanie, and Moss, Stephen
Subjects: AcademicSubjects/MED00290, Infectious Diseases, Oncology, Poster Abstracts
Abstract: Background Clostridioides difficile infection (CDI) is recognised by the CDC as an “urgent threat” in the USA, responsible for nearly 13,000 deaths, and carries an economic burden ranging from &5.4 to &6.3 billion per year. In a phase II study, ridinilazole was shown to be effective at treating CDI and decreasing subsequent recurrence compared to vancomycin. However, the precise mechanism of action of ridinilazole has yet to be fully elucidated. We now present data that reveals ridinilazole clearly co-localises with DNA in C. difficile and binds with high affinity to the minor groove of DNA. These interactions are predicted to have consequences on cellular functions within C. difficile. Methods High resolution confocal microscopy was used to track the intracellular localisation of ridinilazole in C. difficile. Fluorescence intensity was used to characterise the DNA binding properties of ridinilazole; sequence specificity was demonstrated with AT- or GC-rich DNA polymers, and tight binding was shown using short double-stranded oligonucleotides. Hanging drop vapour diffusion enabled co-crystallisation and subsequent structural determination of DNA-bound ridinilazole. Results Confocal microscopy revealed clear co-localisation of ridinilazole to the DNA within C. difficile. Ridinilazole demonstrated a dose-dependent increase in fluorescence in response to increasing concentration of target DNA. Fluorescence binding studies revealed that ridinilazole shows a preference towards AT-rich DNA sequences. Tight binding characteristics were demonstrated by ridinilazole in complex with short double-stranded oligonucleotides, returning dissociation constants (Kd) of 20 – 50 nM. Crystallisation enabled co-structures of ridinilazole bound to the minor groove of double-stranded DNA oligonucleotides to be solved. Conclusion Ridinilazole demonstrates tight binding with sequence specificity within the minor groove of DNA and co-localises with DNA in C. difficle. Further analysis is ongoing to fully understand this novel mechanism of action, the downstream consequences of these interactions and how they contribute to the bactericidal activity of ridinilazole. Disclosures Clive Mason, PhD, Summit Therapeutics (Employee, Shareholder) Tim Avis, n/a, Summit therapeutics (Shareholder) Chris Coward, PhD, Summit Therapeutics (Employee, Scientific Research Study Investigator, Shareholder) David Powell, PhD, Summit Therapeutics (Employee) Kevin W. Garey, Pharm.D., M.S., FASHP, Summit Therapeutics (Research Grant or Support)
Published: 2021

42. Measurement of the γγ→η′ transition form factor

Author: Lees, J. P., Poireau, V., Tisserand, V., Grauges, E., Palano, A., Eigen, G., Brown, D. N., Kolomensky, Yu. G., Fritsch, M., Koch, H., Schroeder, T., Hearty, C., Mattison, T. S., McKenna, J. A., So, R. Y., Blinov, V. E., Buzykaev, A. R., Druzhinin, V. P., Golubev, V. B., Kozyrev, E. A., Kravchenko, E. A., Onuchin, A. P., Serednyakov, S. I., Skovpen, Yu. I., Solodov, E. P., Todyshev, K. Yu., Lankford, A. J., Gary, J. W., Long, O., Eisner, A. M., Lockman, W. S., Panduro Vazquez, W., Chao, D. S., Cheng, C. H., Echenard, B., Flood, K. T., Hitlin, D. G., Kim, J., Li, Y., Miyashita, T. S., Ongmongkolkul, P., Porter, F. C., Röhrken, M., Huard, Z., Meadows, B. T., Pushpawela, B. G., Sokoloff, M. D., Sun, L., Smith, J. G., Wagner, S. R., Bernard, D., Verderi, M., Bettoni, D., Bozzi, C., Calabrese, R., Cibinetto, G., Fioravanti, E., Garzia, I., Luppi, E., Santoro, V., Calcaterra, A., de Sangro, R., Finocchiaro, G., Martellotti, S., Patteri, P., Peruzzi, I. M., Piccolo, M., Rotondo, M., Zallo, A., Passaggio, S., Patrignani, C., Lacker, H. M., Bhuyan, B., Mallik, U., Chen, C., Cochran, J., Prell, S., Gritsan, A. V., Arnaud, N., Davier, M., Le Diberder, F., Lutz, A. M., Wormser, G., Lange, D. J., Wright, D. M., Coleman, J. P., Gabathuler, E., Hutchcroft, D. E., Payne, D. J., Touramanis, C., Bevan, A. J., Di Lodovico, F., Sacco, R., Cowan, G., Banerjee, Sw., Davis, C. L., Denig, A. G., Gradl, W., Griessinger, K., Hafner, A., Schubert, K. R., Barlow, R. J., Lafferty, G. D., Cenci, R., Jawahery, A., Roberts, D. A., Cowan, R., Robertson, S. H., Seddon, R. M., Dey, B., Neri, N., Palombo, F., Cheaib, R., Cremaldi, L., Godang, R., Summers, D. J., Taras, P., De Nardo, G., Sciacca, C., Raven, G., Jessop, C. P., LoSecco, J. M., Honscheid, K., Kass, R., Gaz, A., Margoni, M., Posocco, M., Simi, G., Simonetto, F., Stroili, R., Akar, S., Ben-Haim, E., Bomben, M., Bonneaud, G. R., Calderini, G., Chauveau, J., Marchiori, G., Ocariz, J., Biasini, M., Manoni, E., Rossi, A., Batignani, G., Bettarini, S., Carpinelli, M., Casarosa, G., Chrzaszcz, M., Forti, F., Giorgi, M. A., Lusiani, A., Oberhof, B., Paoloni, E., Rama, M., Rizzo, G., Walsh, J. J., Zani, L., Smith, A. J. S., Anulli, F., Faccini, R., Ferrarotto, F., Ferroni, F., Pilloni, A., Piredda, G., Bünger, C., Dittrich, S., Grünberg, O., Heß, M., Leddig, T., Voß, C., Waldi, R., Adye, T., Wilson, F. F., Emery, S., Vasseur, G., Aston, D., Cartaro, C., Convery, M. R., Dorfan, J., Dunwoodie, W., Ebert, M., Field, R. C., Fulsom, B. G., Graham, M. T., Hast, C., Innes, W. R., Kim, P., Leith, D. W. G. S., Luitz, S., MacFarlane, D. B., Muller, D. R., Neal, H., Ratcliff, B. N., Roodman, A., Sullivan, M. K., Va’vra, J., Wisniewski, W. J., Purohit, M. V., Wilson, J. R., Randle-Conde, A., Sekula, S. J., Ahmed, H., Bellis, M., Burchat, P. R., Puccio, E. M. T., Alam, M. S., Ernst, J. A., Gorodeisky, R., Guttman, N., Peimer, D. R., Soffer, A., Spanier, S. M., Ritchie, J. L., Schwitters, R. F., Izen, J. M., Lou, X. C., Bianchi, F., De Mori, F., Filippi, A., Gamba, D., Lanceri, L., Vitale, L., Martinez-Vidal, F., Oyanguren, A., Albert, J., Beaulieu, A., Bernlochner, F. U., King, G. J., Kowalewski, R., Lueck, T., Nugent, I. M., Roney, J. M., Sobie, R. J., Tasneem, N., Gershon, T. J., Harrison, P. F., Latham, T. E., Prepost, R., Wu, S. L., Lees, J. P., Poireau, V., Tisserand, V., Grauges, E., Palano, A., Eigen, G., Brown, D. N., Kolomensky, Yu. G., Fritsch, M., Koch, H., Schroeder, T., Hearty, C., Mattison, T. S., Mckenna, J. A., So, R. Y., Blinov, V. E., Buzykaev, A. R., Druzhinin, V. P., Golubev, V. B., Kozyrev, E. A., Kravchenko, E. A., Onuchin, A. P., Serednyakov, S. I., Skovpen, Yu. I., Solodov, E. P., Todyshev, K. Yu., Lankford, A. J., Gary, J. W., Long, O., Eisner, A. M., Lockman, W. S., Panduro Vazquez, W., Chao, D. S., Cheng, C. H., Echenard, B., Flood, K. T., Hitlin, D. G., Kim, J., Li, Y., Miyashita, T. S., Ongmongkolkul, P., Porter, F. C., Röhrken, M., Huard, Z., Meadows, B. T., Pushpawela, B. G., Sokoloff, M. D., Sun, L., Smith, J. G., Wagner, S. R., Bernard, D., Verderi, M., Bettoni, D., Bozzi, C., Calabrese, R., Cibinetto, G., Fioravanti, E., Garzia, I., Luppi, E., Santoro, V., Calcaterra, A., de Sangro, R., Finocchiaro, G., Martellotti, S., Patteri, P., Peruzzi, I. M., Piccolo, M., Rotondo, M., Zallo, A., Passaggio, S., Patrignani, C., Lacker, H. M., Bhuyan, B., Mallik, U., Chen, C., Cochran, J., Prell, S., Gritsan, A. V., Arnaud, N., Davier, M., Le Diberder, F., Lutz, A. M., Wormser, G., Lange, D. J., Wright, D. M., Coleman, J. P., Gabathuler, E., Hutchcroft, D. E., Payne, D. J., Touramanis, C., Bevan, A. J., Di Lodovico, F., Sacco, R., Cowan, G., Banerjee, Sw., Davis, C. L., Denig, A. G., Gradl, W., Griessinger, K., Hafner, A., Schubert, K. R., Barlow, R. J., Lafferty, G. D., Cenci, R., Jawahery, A., Roberts, D. A., Cowan, R., Robertson, S. H., Seddon, R. M., Dey, B., Neri, N., Palombo, F., Cheaib, R., Cremaldi, L., Godang, R., Summers, D. J., Taras, P., De Nardo, G., Sciacca, C., Raven, G., Jessop, C. P., Losecco, J. M., Honscheid, K., Kass, R., Gaz, A., Margoni, M., Posocco, M., Simi, G., Simonetto, F., Stroili, R., Akar, S., Ben-Haim, E., Bomben, M., Bonneaud, G. R., Calderini, G., Chauveau, J., Marchiori, G., Ocariz, J., Biasini, M., Manoni, E., Rossi, A., Batignani, G., Bettarini, S., Carpinelli, M., Casarosa, G., Chrzaszcz, M., Forti, F., Giorgi, M. A., Lusiani, A., Oberhof, B., Paoloni, E., Rama, M., Rizzo, G., Walsh, J. J., Zani, L., Smith, A. J. S., Anulli, F., Faccini, R., Ferrarotto, F., Ferroni, F., Pilloni, A., Piredda, G., Bünger, C., Dittrich, S., Grünberg, O., Heß, M., Leddig, T., Voß, C., Waldi, R., Adye, T., Wilson, F. F., Emery, S., Vasseur, G., Aston, D., Cartaro, C., Convery, M. R., Dorfan, J., Dunwoodie, W., Ebert, M., Field, R. C., Fulsom, B. G., Graham, M. T., Hast, C., Innes, W. R., Kim, P., Leith, D. W. G. S., Luitz, S., Macfarlane, D. B., Muller, D. R., Neal, H., Ratcliff, B. N., Roodman, A., Sullivan, M. K., Va’Vra, J., Wisniewski, W. J., Purohit, M. V., Wilson, J. R., Randle-Conde, A., Sekula, S. J., Ahmed, H., Bellis, M., Burchat, P. R., Puccio, E. M. T., Alam, M. S., Ernst, J. A., Gorodeisky, R., Guttman, N., Peimer, D. R., Soffer, A., Spanier, S. M., Ritchie, J. L., Schwitters, R. F., Izen, J. M., Lou, X. C., Bianchi, F., De Mori, F., Filippi, A., Gamba, D., Lanceri, L., Vitale, L., Martinez-Vidal, F., Oyanguren, A., Albert, J., Beaulieu, A., Bernlochner, F. U., King, G. J., Kowalewski, R., Lueck, T., Nugent, I. M., Roney, J. M., Sobie, R. J., Tasneem, N., Gershon, T. J., Harrison, P. F., Latham, T. E., Prepost, R., and Wu, S. L.
Abstract: We study the process e+e−→e+e−η′ in the double-tag mode and measure for the first time the γ⋆γ⋆→η′ transition form factor Fη′(Q12,Q22) in the momentum-transfer range 2
Published: 2018

43. A new approach to homotopy perturbation method for solving systems of Volterra integral equations of first kind

Author: S. Ahamed M., Kamrul Hasan M., and S. Alam M.
Subjects: General Computer Science
Published: 2017

44. Intra-Operative Electronic Brachytherapy in the Treatment of Early Stage Breast Cancer – A Multi-Center Trial, Technique and Preliminary Results

Author: Alam M Nisar Syed
Subjects: Cancer Research, medicine.medical_specialty, Radiation, Intra operative, business.industry, medicine.medical_treatment, Brachytherapy, medicine.disease, Breast cancer, Oncology, medicine, Radiology, Nuclear Medicine and imaging, Center (algebra and category theory), Radiology, Stage (cooking), business
Published: 2020

45. A Study on Screw Fastened Profile Steel Sheet Subjected to Simulated Uplift Load

Author: Islam, S. M. Z., Ahmed, B., Rahman, H., and Alam, M. W.
Subjects: local failure, Coupon test, roofing, uplift load, screw fastener, profiled sheet
Abstract: Profiled steel sheets play an important role in light gauge metal building construction, particularly as roof claddings in houses, low-rise commercial and industrial buildings. Thin profiled steel sheets are commonly connected to the underlying purlins or steel trusses/frame by drilling or tapping of screws. Screw fastened light gauge steel profiled roofing sheets are mostly subjected to wind suction or wind uplift forces. Strong and fluctuating wind uplift force may fail locally in the vicinity of screw. Different types of ribbed have great significance on the structural strength and behaviour of profile steel sheet. The objective of this study is to investigate the structural strength and behaviour of different profiled steel sheet roofing elements under simulated wind uplift forces. A series of tests was performed on profiled steel sheet roofing subjected to wind uplift simulated pressure. Three different ribbed sheets namely; arc-tangent, tile type and trapezoidal profiled steel sheet are investigated in this research. Different diameter of screw and different span length of sheeting are considered in this research. The failure loads, failure modes the load- deformation behaviour of screwed fastened profile steel sheet under simulated wind load are presented. It was observed that during the increase of loading, the upward deflection of the unscrewed crest became larger than that of the screwed crest. It was found that the local diamond-shaped deformations may progressively develop around the screw fasteners at the support due to uplift load. It was found that structural behaviour of the roofing sheets under uplift loads was greatly dependent on different types of ribbed, diameter of the screw and span length of profiled steel sheet. Based on test results, tiles type profiled steel sheet provided better performance than others types. Finally, the finite element analysis (FEA) investigation is conducted to explore the investigation on structural strength and behaviour of different types profiled steel sheet roofing elements under simulated wind uplift. Good agreements are found between test and numerical results
Published: 2019
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46. Sample Size Calculations in Simple Linear Regression: Trials and Tribulations

Author: Guan, Tianyuan, Alam, M. Khorshed, and Rao, M. Bhaskara
Subjects: Methodology (stat.ME), FOS: Computer and information sciences, Statistics - Methodology
Abstract: The problem tackled in this paper is the determination of sample size for a given level and power in the context of a simple linear regression model. At a technical level, the simple linear regression model is a five-parameter model. It is natural to base sample size calculations on the least squares' estimator of the slope parameter of the model. Nuisance parameters such as the variance of the predictor X and conditional variance of the response Y create problems in the calculations. The current approaches in the literature are not illuminating. One approach is based on the conditional distribution of the estimator of the slope parameter given the data on the predictor X. Another approach is based on the sample correlation coefficient. We overcome the problems by determining the exact unconditional distribution of the test statistic built on the estimator of the slope parameter. The exact unconditional distribution alleviates difficulties to some extent in the computation of sample sizes. On the other hand, the test based on the sample correlation coefficient of X and Y avoids the problems besetting the test based on the slope parameter. However, we lose intuitive interpretation that comes with the slope parameter. Surprisingly, we see that the sample size that comes from the correlation test works in synchronization with the one that comes from the test built upon the slope parameter in a broad array of settings., Comment: 20 pages, 1 figure and 7 tables
Published: 2019
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47. Physico-chemical, functional properties and storage characteristics of jackfruit

Author: Sultana, A, Parvin, R, Alam, M, Akter, F, Alim, M, and Hossain, Mohammad Alamgir
Published: 2019
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48. Weak production of strange $��$ baryons off the nucleon

Author: Alam, M. Rafi and Simo, I. Ruiz
Subjects: Nuclear Theory (nucl-th), High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), Nuclear Theory, High Energy Physics::Phenomenology, FOS: Physical sciences, High Energy Physics::Experiment, Nuclear Experiment
Abstract: The charged current Cabibbo-supressed associated $K ��$ production off the nucleon induced by anti-neutrinos is studied at low and intermediate energies. The non-resonant terms are obtained using a microscopical model based on the SU(3) chiral Lagrangian. The basic parameters of the model are $f_��$, the pion decay constant, Cabibbo's angle, the proton and neutron magnetic moments and the axial vector coupling constants for the baryons octet, D and F, that are obtained from the analysis of the semileptonic decays of neutron and hyperons. In addition, we also consider $��^\ast(1385)$ resonance, which can decay in $K ��$ final state when this channel is open. The studied mechanism is the prime source of $��$ production at anti-neutrino energies around $2$ GeV and the calculated cross sections at these energies can be measured at the current and future neutrino experiments., 10 pages, 4 figures, 3 tables
Published: 2019
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49. Search for $B^- \to ��\bar p ��\bar��$ with the BABAR experiment

Author: The BABAR Collaboration, Lees, J. P., Poireau, V., Tisserand, V., Grauges, E., Palano, A., Eigen, G., Brown, D. N., Kolomensky, Yu. G., Fritsch, M., Koch, H., Schroeder, T., Cheaib, R., Hearty, C., Mattison, T. S., McKenna, J. A., So, R. Y., Blinov, V. E., Buzykaev, A. R., Druzhinin, V. P., Golubev, V. B., Kozyrev, E. A., Kravchenko, E. A., Onuchin, A. P., Serednyakov, S. I., Skovpen, Yu. I., Solodov, E. P., Todyshev, K. Yu., Lankford, A. J., Dey, B., Gary, J. W., Long, O., Eisner, A. M., Lockman, W. S., Vazquez, W. Panduro, Chao, D. S., Cheng, C. H., Echenard, B., Flood, K. T., Hitlin, D. G., Kim, J., Li, Y., Miyashita, T. S., Ongmongkolkul, P., Porter, F. C., R��hrken, M., Huard, Z., Meadows, B. T., Pushpawela, B. G., Sokoloff, M. D., Sun, L., Smith, J. G., Wagner, S. R., Bernard, D., Verderi, M., Bettoni, D., Bozzi, C., Calabrese, R., Cibinetto, G., Fioravanti, E., Garzia, I., Luppi, E., Santoro, V., Calcaterra, A., de Sangro, R., Finocchiaro, G., Martellotti, S., Patteri, P., Peruzzi, I. M., Piccolo, M., Rotondo, M., Zallo, A., Passaggio, S., Patrignani, C., Lacker, H. M., Bhuyan, B., Mallik, U., Chen, C., Cochran, J., Prell, S., Gritsan, A. V., Arnaud, N., Davier, M., Diberder, F. Le, Lutz, A. M., Wormser, G., Lange, D. J., Wright, D. M., Coleman, J. P., Gabathuler, E., Hutchcroft, D. E., Payne, D. J., Touramanis, C., Bevan, A. J., Di Lodovico, F., Sacco, R., Cowan, G., Banerjee, Sw., Davis, C. L., Denig, A. G., Gradl, W., Griessinger, K., Hafner, A., Schubert, K. R., Barlow, R. J., Lafferty, G. D., Cenci, R., Jawahery, A., Roberts, D. A., Cowan, R., Robertson, S. H., Seddon, R. M., Neri, N., Palombo, F., Cremaldi, L., Godang, R., Summers, D. J., Taras, P., De Nardo, G., Sciacca, C., Raven, G., Jessop, C. P., LoSecco, J. M., Honscheid, K., Kass, R., Gaz, A., Margoni, M., Posocco, M., Simi, G., Simonetto, F., Stroili, R., Akar, S., Ben-Haim, E., Bomben, M., Bonneaud, G. R., Calderini, G., Chauveau, J., Marchiori, G., Ocariz, J., Biasini, M., Manoni, E., Rossi, A., Batignani, G., Bettarini, S., Carpinelli, M., Casarosa, G., Chrzaszcz, M., Forti, F., Giorgi, M. A., Lusiani, A., Oberhof, B., Paoloni, E., Rama, M., Rizzo, G., Walsh, J. J., Zani, L., Smith, A. J. S., Anulli, F., Faccini, R., Ferrarotto, F., Ferroni, F., Pilloni, A., Piredda, G., B��nger, C., Dittrich, S., Gr��nberg, O., He��, M., Leddig, T., Vo��, C., Waldi, R., Adye, T., Wilson, F. F., Emery, S., Vasseur, G., Aston, D., Cartaro, C., Convery, M. R., Dorfan, J., Dunwoodie, W., Ebert, M., Field, R. C., Fulsom, B. G., Graham, M. T., Hast, C., Innes, W. R., Kim, P., Leith, D. W. G. S., Luitz, S., MacFarlane, D. B., Muller, D. R., Neal, H., Ratcliff, B. N., Roodman, A., Sullivan, M. K., Va'vra, J., Wisniewski, W. J., Purohit, M. V., Wilson, J. R., Randle-Conde, A., Sekula, S. J., Ahmed, H., Bellis, M., Burchat, P. R., Puccio, E. M. T., Alam, M. S., Ernst, J. A., Gorodeisky, R., Guttman, N., Peimer, D. R., Soffer, A., Spanier, S. M., Ritchie, J. L., Schwitters, R. F., Izen, J. M., Lou, X. C., Bianchi, F., De Mori, F., Filippi, A., Gamba, D., Lanceri, L., Vitale, L., Martinez-Vidal, F., Oyanguren, A., Albert, J., Beaulieu, A., Bernlochner, F. U., King, G. J., Kowalewski, R., Lueck, T., Nugent, I. M., Roney, J. M., Sobie, R. J., Tasneem, N., Gershon, T. J., Harrison, P. F., Latham, T. E., Prepost, R., and Wu, S. L.
Subjects: High Energy Physics - Experiment (hep-ex), FOS: Physical sciences
Abstract: We search for the rare flavor-changing neutral current process $B^- \to ��{\overline p} ��{\overline��}$ using data from the BABAR experiment. A total of 424 fb$^{-1}$ of $e^+e^-$ collision data collected at the center-of-mass energy of the $��$(4S) resonance is used in this study, corresponding to a sample of ${(471 \pm 3) \times 10^{6}}$ $B\overline{B}$ pairs. Signal $B^- \to ��{\overline p} ��{\overline��}$ candidates are identified by first fully reconstructing a $B^+$ decay in one of many possible exclusive decays to hadronic final states, then examining detector activity that is not associated with this reconstructed $B^+$ decay for evidence of a signal $B^- \to ��{\overline p} ��{\overline��}$ decay. The data yield is found to be consistent with the expected background contribution under a null signal hypothesis, resulting in an upper limit of ${{\cal B} (B^- \to ��{\overline p} ��{\overline��}) < 3.0\times 10^{-5}}$ at the $90\%$ confidence level., 10 pages, 7 figures
Published: 2019
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50. Automated quantum programming via reinforcement learning for combinatorial optimization

Author: McKiernan, Keri A., Davis, Erik, Alam, M. Sohaib, and Rigetti, Chad
Subjects: FOS: Computer and information sciences, Quantum Physics, Computer Science - Machine Learning, ComputerSystemsOrganization_MISCELLANEOUS, TheoryofComputation_GENERAL, FOS: Physical sciences, Quantum Physics (quant-ph), Machine Learning (cs.LG)
Abstract: We develop a general method for incentive-based programming of hybrid quantum-classical computing systems using reinforcement learning, and apply this to solve combinatorial optimization problems on both simulated and real gate-based quantum computers. Relative to a set of randomly generated problem instances, agents trained through reinforcement learning techniques are capable of producing short quantum programs which generate high quality solutions on both types of quantum resources. We observe generalization to problems outside of the training set, as well as generalization from the simulated quantum resource to the physical quantum resource.
Published: 2019
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