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Though research on Israel/Palestine often privileges the macro-geopolitical perspective, a growing body of work has begun to catalogue the ways in which the violence of occupation is carried out through intimate spaces and practices. However, often missing from such accounts is an understanding of intimacy as a counter-veiling political force. Looking at the ‘Love Under Apartheid’ project in Palestine, and queer anti-occupation organising in Israel, this paper considers how storytelling can serve as both a research methodology and political intervention, changing the way geopolitical stories are told and unfold.

Multi-touch surfaces have the potential to change the nature of computer-supported collaborative learning, allowing more equitable access to shared digital content. In this paper, we explore how large multi-touch tables can be used by groups of students as an external representation of their group interaction processes. Video data from 24 groups of students working on a logic reasoning problem was examined to identify their levels of reasoning about the task, and how they used the table to support their reasoning. Results indicate that of the 13 groups who solved or nearly solved the problem, 12 used the table to represent their reasoning process, while only four groups who used the table to support their reasoning process did not solve the problem. Examples from three groups are used to explore the different ways the table was used as an external representation of the groups' processes. The findings indicate that the group problem-solving process can be enhanced with the use of multi-touch tables, although students may need support in using the technology effectively to support their collaborative reasoning.

This paper evaluates whether nature of the union moderates the antecedents of union commitment and participation, based on a study of member attitudes in Voice, formerly the Professional Association of Teachers, and the National Unions of Teachers, often seen as the most “moderate and “militant” teacher unions respectively.

Mega-scale glacial lineations (MSGLs) are a characteristic landform on ice stream beds. Solving the puzzle of their formation is key to understanding how ice interacts with its bed and how this, in turn, influences the dynamics of ice streams. However, a comprehensive and detailed characterization of this landform's size, shape and spatial arrangement, which might serve to test and refine formational theories, is largely lacking. This paper presents a detailed morphometric analysis and comparison of 4043 MSGLs from eight palaeo-ice stream settings: three offshore (Norway and Antarctica), four onshore (Canada), and one from under a modern ice stream in West Antarctica. The length of MSGLs is lower than previously suggested (mode 1000–2000 m; median 2892 m), and they initiate and terminate at various locations on an ice stream bed. Their spatial arrangement reveals a pattern that is characterized by an exceptional parallel conformity (80% of all mapped MSGLs have an azimuth within 5° from the mean values), and a fairly constant lateral spacing (mode 200–300 m; median 330 m), which we interpret as an indication that MSGLs are a spatially self-organized phenomenon. Results show that size, shape and spatial arrangement of MSGLs are consistent both within and also generally between different ice stream beds. We suggest this results from a common mechanism of formation, which is largely insensitive to local factors. Although the elongation of MSGLs (mode 6–8; median 12.2) is typically higher than features described as drumlins, these values and those of their width (mode 100–200 m; median 268 m) overlap, which suggests the two landforms are part of a morphological continuum and may share a similar origin. We compare their morphometry with explicit predictions made by the groove-ploughing and rilling instability theories of MSGL formation. Although the latter was most compatible, neither is fully supported by observations.

Key termsequine; immunophenotype; ISCTmarkersThere has been growing interest in recent years in the use ofmesenchymal stem cells (MSCs) as a potential treatment fora number of important diseases. MSCs were first describedas colony-forming units consisting of fibroblast-like cellsderived from bone marrow (1). Since then they have beenisolated from many different tissues such as adipose, muscle,synovium, dental pulp, tendon, peripheral blood, Wharton’sjelly, and umbilical cord blood (2–4). The biological charac-teristics of MSCs that contribute to their therapeutic activityand the mechanisms of action continue to be studied.Despite many advances in MSC therapy, a specific markerthat defines cultured MSCs and identifies them within theirtissue niche has remained elusive. As a consequence, theInternational Society of Cell Therapy (ISCT) proposed a setof minimal test criteria for human MSCs as a first attempt atstandardization for laboratory and preclinical research. Thesecriteria include plastic adherence, trilineage differentiation toosteoblast, adipocyte, and chondrocyte lineages, and a phe-notype relating to surface marker expression. This latter stip-ulates that MSCs, measured by flow cytometry, must show 95% positivity for CD73, CD90, and CD105 antigens and 2% for CD45, CD34, CD14 or CD11b, CD79a or CD19,and HLA class II (5).These criteria were established only for human MSCresearch. However, the study of MSCs is not limited to humanapplications: many animal models are routinely used in pre-clinical investigation and in veterinary applications. There isan urgent need for a universal marker(s) to define and identifyMSCs from all tissues of origin, which will apply across allspecies.There has been an interest in equine MSC therapy formore than 10 years, especially in the treatment of musculo-skeletal disorders such as tendon or joint disease. In addition,because of similarities in terms of structure and biomechanics,the horse is accepted by the US Food and Drug Administra-tion as an animal model suitable for the investigation of carti-lage and tendon repair therapies for human use. In recentyears, several equine trials have been carried out using MSCsfrom different sources. Most of these reported a positive out-come (6) although the mechanism of action remains unclear.It can be argued that failure to understand the biologicalmechanism of repair hinders development of optimized thera-pies. It can also be argued that the lack of meaningful potencytests will hamper the development of standardized cell prepa-rations. The most important identifying characteristics ofequine MSCs have been plastic adhesion and trilineage poten-tial. The use of cell surface markers has been limited due tothe lack of commercial antibodies that cross-react with equineantigens (7).The paper published in this issue (p. XXX) by Paebstet al. is the first to analyze the complete panel of human MSCmarkers established by the ISCT in equine MSCs derived fromfive different tissue sources (marrow, adipose, tendon, umbili-cal cord tissue, and umbilical cord blood).

Confidence intervals (Cis) in principal component analysis (PCA) can be based on asymptotic standard errors and on the bootstrap methodology. The present paper offers an overview of possible strategies for bootstrapping in PCA. A motivating example shows that Ci estimates for the component loadings using different methods may diverge. We explain that this results from both differences in quality and in perspective on the rotational freedom of the population loadings. A comparative simulation study examines the quality of various estimated component loading Cis. The bootstrap approach is more flexible and generally yields better Cis than the asymptotic approach. However, in the case of a clear simple structure of varimax rotated loadings, one can be confident that the asymptotic estimates are reasonable as well.

The current paper combines research from personality, cultural, social, and work- and organizational psychology. More precisely, it addresses the motivating effects of situations that either foster or inhibit social loafing under typical vs maximum performance conditions. It further tests how these effects are moderated by the three individual difference variables of conscientiousness, agreeableness, and openness to experience, and the two cultural dimension variables of collectivism and power distance. Results reveal positive main effects for inherently motivating situations, maximum performance conditions, conscientiousness, agreeableness and collectivism, as well as a significant interaction between the degree to which the situation invites social loafing and the typical vs maximum performance condition. These findings thus confirm a possible overlap between the theories of social loafing and of typical vs maximum performance. Finally, power distance showed a number of surprising interactions that may, in part, account for cultural differences found in the social loafing literature. Implications for theory building, empirical research and practice are discussed.

In communication networks used by constant bit rate applications, call-level dynamics (i.e. entering and leaving calls) lead to fluctuations in the load, and therefore also fluctuations in the delay (jitter). By intentionally delaying the packets at the destination, one can transform the perturbed packet stream back into the original periodic stream; in other words: there is a trade off between jitter and delay, in that jitter can be removed at the expense of delay. As a consequence, for streaming applications for which the packet delay should remain below some predefined threshold, it is desirable that the jitter remains small.This paper presents a set of procedures to compute the jitter due to call-level variations. We consider a network resource shared by a fluctuating set of constant bit rate applications (modelled as periodic sources). As a first step, we study the call-level dynamics: supposing that a tagged call sees n0 calls when entering the system, then we compute the probability that at the end of its duration (consisting of, say, i packets) ni calls are present, of which n0,i stem from the original n0 calls. As a second step, we show how to compute the jitter, for given n0, ni, and n0,i; in this analysis generalised Ballot-problems have to be solved. We find an iterative exact solution to these, and explicit approximations and bounds. Then, as a final step, the (packet-level) results of the second step are weighed with the (call-level) probabilities of the first step, thus resulting in the probability distribution of the jitter experienced within the call duration. An explicit Gaussian approximation is proposed. Extensive numerical experiments validate the accuracy of the approximations and bounds. Copyright © 2006 AEIT

Over the last decade, the study of social interactions in economic decision making has become an important area of research. The main objective of this paper is to survey the extent to which recent empirical contributions have succeeded in overcoming the identification problems as first formulated by Manski (1993). This discussion is followed by a comparison of empirical studies in three key areas of research: neighborhood effects, substance use among teenagers, and peer effects among university roommates. Finally, I discuss questions like: Can economists restrict attention to a specific subcategories of social interactions? How do we define social groups, and what is the importance of social interactions for public policy?

This paper summarises the vast evidence on micro price-setting recently obtained for euro area countries. We consider studies with micro data on consumer and producer prices, as well as survey information. The main findings are: (1) prices in the euro area are sticky and stickier than in the US; (2) downward price rigidity is only slightly more marked than upward price rigidity; (3) heterogeneity and asymmetries are observed in price-setting; and (4) the relevance of theories that explain price stickiness, such as implicit or explicit contracts, marginal costs, and coordination failure, is confirmed, whereas menu costs, pricing thresholds, and costly information explanations are judged much less relevant by firms. (JEL: C25, D40, E31)

The key thesis in Hubbard’s paper ‘Accommodating Otherness: anti-asylum centre protest and the maintenance of white privilege’ is that racial dimensions of opposition to asylum seekers centres are part of cultural NIMBY ism. This connection of complex issues with an invalid concept obscures our understanding of the role of ‘otherness’ in facility siting discussions. The deconstruction of the contested NIMBY concept is illustrated by a brief review of wind power, which was mentioned as a field in which ‘otherness’ had not been incorporated.

Lead antimonate yellow, or Naples Yellow, is one of the most common yellow pigments in Western European art. It was used mainly in the period from 1500 to 1850. During the 18th and 19th centuries, a whole range of production recipes was published. However, the early production history of the pigment is not well understood. In this paper, a study of two early production recipes is reported. Under the nomenclature of potters' yellow, the recipes describe some production details of the pigment. Reconstructions of the historical lead antimonate yellow were made according to these sources. X-ray powder diffraction (XRPD) was used to examine the reaction products. Our findings show that various types of lead antimonate yellow can be formed, following the descriptions given in the recipes. Some of these types, notably lead-tin antimonate, have been found in earlier studies of authentic works of art. No evidence was found for a locally limited use of this pigment, as has previously been suggested. Documentary and analytical evidence indicates that the knowledge on lead antimonate yellows originates from Middle Eastern ceramic and glass industries. it is argued that the know-how on the production of lead antimonate yellows has been transferred via the migration of glass artists from the Eastern Mediterranean to Venice during the 15th century.

The number of inhabitants of the four largest Dutch cities, Amsterdam, Rotterdam, The Hague and Utrecht, has stabilised since the mid-1980s. This stability in population size, however, hides considerable dynamics in population composition, especially regarding ethnicity, household type and socio-economic status. In this paper, we focus on the influence of international migration and residential migration flows on changing ethnic population structure. A selective residential outflow of natives and influx of foreigners, together with higher natural growth of ethnic minority groups, have contributed to very fast changes in ethnic composition of the four largest Dutch cities. The latest national population forecasts of Statistics Netherlands in December 2004 indicate an ongoing influx of foreign population groups into the Netherlands for the decades to come, despite the recent more restrictive immigration policy. One can expect from this a continuous international migration towards the large Dutch cities in particular. If the observed trend in native outflow continues, the foreign city population will soon cross the 50 per cent mark.

Objectives: The Stress Thermometer is an easily accessible Internet-based instrument for feedback on work stress and burnout. The aim of this paper is to describe the development of this instrument and to determine its applicability within the dental practice. Methods: The Stress Thermometer was made accessible to all members of the Dutch Dental Association, of which 77% of all Dutch dentists are members. Frequency of use was determined, and descriptive data was collected. Results: During an evaluation period of 5 months at least 12% of all possible respondents made use of the Stress Thermometer. Descriptive characteristics of the response group, as well as levels of burnout and work stress, corresponded with those found in the Dutch dentist population. However, some deviations were also present. Conclusions: Results indicate the applicability of the Stress Thermometer to a representative variety of dentists. Although the deviations found should not be ignored in future use, the Stress Thermometer was successful in reaching a population that is difficult to reach. It effectively calls attention to sensitive personal issues concerning work-related stress and burnout.

This paper has two aims. The first is to exposit the various forms of the LM statistic and to collect together some of the relevant research reported in the mathematical statistics literature. The second is to illustrate the construction of LM tests by considering a number of particular econometric specifications as examples. It will be found that in many instances the LM statistic can be computed by a regression using the residuals of the fitted model which, because of its simplicity, is itself estimated by OLS. The paper contains five sections. In Section 2, the LM statistic is outlined and some alternative versions of it are discussed. Section 3 gives the derivation of the statistic for several econometric specifications. Applications in this section are the testing for a liquidity trap, autocorrelation, the error components model, diagonality of a covariance matrix in seemingly unrelated equation systems and choice between models generated by separate families of distributions. Section 4 considers the construction of a pseudo-LM statistic when estimation is difficult even under the null hypothesis and discusses the derivation of the exact distribution of the statistic. A concluding summary is given as Section

The landmark decision ofGillick v West Norfolk Area Health Authoritywas a victory for advocates of adolescent autonomy. It established a test by which the court could measure children's competence with a view to them authorising medical treatment. However, application of the test by clinicians reveals a number of ambiguities which are compounded by subsequent interpretation ofGillickin the law courts. What must be understood by minors in order for them to be deemed competent? At what point in the consent process should competence be assessed? Does competence confer on minors the authority to refuse as well as to accept medical treatment? These are questions which vex clinicians, minors and their families. A growing number of commentators favour application of parts of the Mental Capacity Act 2005 to minors. In this paper, the limitations of this approach are exposed and more radical reform is proposed.

Manuscript Type: Empirical Research Question: The objective of this paper is to study the impact that directors who represent institutional investors have on the quality of financial reporting. We focus on those who maintain business relations with the firm on whose board they sit (pressure sensitive directors), and analyze their influence both on Boards and Audit Committees. Additionally, we examine the specific role of bank directors on Boards and Audit Committees and examine their effects on the quality of information when they act as shareholders and directors. Research Findings/Insights: Our results suggest that institutional directors are an effective monitoring device that leads to higher quality of financial reporting and, therefore, to less likelihood of qualified audit reports. Consistent with the relevant role of business relations with the firm, we find that directors appointed by pressure sensitive investors, both in Boards and Audit Committees, have a higher impact on the unqualified audit opinion. Nevertheless, when analyzing separately, only savings banks representatives on the Board increase the pressure to issue a clean audit opinion. Theoretical/Academic Implications: The results confirm that Board characteristics have an important influence on financial reporting quality, in line with the views that have been expressed by several international bodies (e.g., FRC, 2003; OECD, 2004). The findings also suggest that both researchers and policy makers should no longer consider institutional investors as a whole, since directors appointed by different types of institutional investors have various implications on the audit opinion. Practitioner/Policy Implications: This study makes its core contribution by empirically showing that directors appointed by different types of institutional investors have diverse implications on the audit opinion. This evidence could be potentially helpful in providing a basis for regulatory actions, namely those aiming to influence the structure of the Board of directors. The results have significant implications for supervisors and regulators, whose role in safeguarding the financial system will benefit from an understanding of how the presence of savings banks and commercial banks in non-financial firms Boards impacts audit opinion in a bank-based system.

This is the peer reviewed version of the following article: Poveda, David; Jociles, María Isabel; Rivas, Ana María (2014). Socialization into single-parent-by-choice family life. Journal of Sociolinguistics 18, 3: 319-344, which has been published in final form at http://dx.doi.org/10.1111/josl.12085. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving, This paper examines family interactions between mothers and children in single-parent-by-choice (SPBC) families in Spain. The data is part of a larger multi-sited ethnographic study focused on emergent family structures that examined families formed by women who began their family projects through adoption or assisted reproduction. Single-mothers-by-choice formulate various socialization goals that are tied to the complexities of their non-conventional family project. These goals are also realized in daily conversation, particularly when families talk about future events in their lives. Our findings expand existing family language socialization research in Western contexts, which has primarily focused on conventional twoparent families, and invite developing a stronger dialogue between family language socialization research and current debates on changing kinship structures in post-industrial societies, Este trabajo examina interacciones entre madres e hijos/as en familias de madres solteras por eleccion (MSPE) en España. Los datos provienen de una investigación etnográfica multi-lugar más amplia centrada en modelos familiares emergentes que estudió a familias formadas por mujeres solas que han comenzado su proyecto familiar a trav és de la reproducción asistida o la adopción. La madres solteras por elección formulan varias metas de socialización que están ligadas a las complejidades y demandas de su proyecto familiar no convencional. Estos objetivos también se plasman en conversaciones cotidianas, especialmente cuando las familias hablan sobre eventos futuros en su vidas. Nuestros resultados amplían la investigación sobre socializacion linguíıstica familiar en contextos occidentales, que se ha centrado principalmente en familias bi-parentales convencionales, e invitan a desarrollar un diálogo máas fructífero entre la investigación sobre socialización lingüística familiar y los debates actuales en torno a cambios en los patrones de parentesco en sociedades post-industriales

In this paper, we present a new technique to estimate varying coefficient models of unknown form in a panel data framework where individual effects are arbitrarily correlated with the explanatory variables in an unknown way. The estimator is based on first differences and then a local linear regression is applied to estimate the unknown coefficients. To avoid a non-negligible asymptotic bias, we need to introduce a higher-dimensional kernel weight. This enables us to remove the bias at the price of enlarging the variance term and, hence, achieving a slower rate of convergence. To overcome this problem, we propose a one-step backfitting algorithm that enables the resulting estimator to achieve optimal rates of convergence for this type of problem. It also exhibits the so-called oracle efficiency property. We also obtain the asymptotic distribution. Because the estimation procedure depends on the choice of a bandwidth matrix, we also provide a method to compute this matrix empirically. The Monte Carlo results indicate the good performance of the estimator in finite samples.

This paper presents in-depth qualitative research on three small professional service firms whose owner-managers sought to introduce greater degrees of formality in their firms' working practices and employment relationships. We focus on humour as an ambiguous medium of informality, yet viewed by owner-managers as a tool at their disposal. However, while early studies of humour in small and medium-sized enterprises support such a functionalist view, our findings indicate its significant limitations. We argue that humour obscures but does not resolve disjunctive interests and it remains stubbornly ambiguous and resistant to attempts to functionalize it. Our findings contribute to studies of humour in small and medium-sized enterprises by challenging its utility as a means of managerial control or employee resistance. They also contribute to studies of employment relationships by exploring humour's potentially disruptive influence within the formality-informality span, especially as small and medium-sized enterprises seek greater degrees of formalization, with implications for how those relationships are conducted and (re)negotiated on an ongoing basis. © 2012 British Academy of Management.

Aim The misuse and abuse of Enduring Powers of Attorney (EPAs) by attorneys, particularly in relation to financial decision-making, is a growing concern. This paper explores the opportunities to enhance accountability of attorneys at the time of the execution of the document in Queensland. Method A four stage multi-method design comprised a critical reference group; semi-structured interviews with 32 principals or potential principals, attorneys and witnesses; two focus groups with service providers and a state wide survey of 76 principals, attorneys and witnesses. Results Across all methods and user groups, understanding the role and obligations of the attorney in an EPA was consistently identified as problematic. Conclusions Promoting accountability and understanding can be addressed by greater attention to the role of the attorney in the forms/ guidelines and in the structure and witnessing of the forms, increased direction about record keeping and access to appropriate advice and support.

In this paper we present the results of an international survey among 313 CFOs o

The Partition of Unity Method has become an attractive approach for extending the allowable frequency range for wave simulations beyond that available using piecewise polynomial elements. The non-uniqueness of solution obtained from the conventional boundary integral equation (CBIE) is well known. The CBIE derived through Green's identities suffers from a problem of non-uniqueness at certain characteristic frequencies. Two of the standard methods of overcoming this problem are the so-called Combined Helmholtz Integral Equation Formulation (CHIEF) method and that of Burton and Miller. The latter method introduces a hypersingular integral, which may be treated in various ways. In this paper, we present the collocation partition of unity boundary element method (PUBEM) for the Helmholtz problem and compare the performance of CHIEF against a Burton–Miller formulation regularised using the approach of Li and Huang.

In this paper, we argue for an approach that goes beyond an institutional reading of urban climate governance to engage with the ways in which government is accomplished through social and technical practices. Central to the exercise of government in this manner, we argue, are ‘climate change experiments’– purposive interventions in urban socio-technical systems designed to respond to the imperatives of mitigating and adapting to climate change in the city. Drawing on three different concepts – of governance experiments, socio-technical experiments, and strategic experiments – we first develop a framework for understanding the nature and dynamics of urban climate change experiments. We use this conceptual analysis to frame a scoping study of the global dimensions of urban climate change experimentation in a database of 627 urban climate change experiments in 100 global cities. The analysis charts when and where these experiments occur, the relationship between the social and technical aspects of experimentation and the governance of urban climate change experimentation, including the actors involved in their governing and the extent to which new political spaces for experimentation are emerging in the contemporary city. We find that experiments serve to create new forms of political space within the city, as public and private authority blur, and are primarily enacted through forms of technical intervention in infrastructure networks, drawing attention to the importance of such sites in urban climate politics. These findings point to an emerging research agenda on urban climate change experiments that needs to engage with the diversity of experimentation in different urban contexts, how they are conducted in practice and their impacts and implications for urban governance and urban life.

Research in the area of spatial decision support (SDS) and resource allocation has recently generated increased attention for integrating optimization techniques with GIS. In this paper we address the use of spatial optimization techniques for solving multi-site land-use allocation (MLUA) problems, where MLUA refers to the optimal allocation of multiple sites of different land uses to an area. We solve an MLUA problem using four different integer programs (IP), of which three are linear integer programs. The IPs are formulated for a raster-based GIS environment and are designed to minimize development costs and to maximize compactness of the allocated land use. The preference for either minimizing costs or maximizing compactness has been made operational by including a weighting factor. The IPs are evaluated on their speed and their efficacy for handling large databases. All four IPs yielded the optimal solution within a reasonable amount of time, for an area of 8 × 8 cells. The fastest model was successfully applied to a case study involving an area of 30 × 30 cells. The case study demonstrates the practical use of linear IPs for spatial decision support issues.

In this study, we extend imaging and modeling work that was done in Part I of this report for a pure cellulose substrate (filter paper) to more industrially relevant substrates (untreated and pretreated hardwood and switchgrass). Using confocal fluorescence microscopy, we are able to track both the structure of the biomass particle via its autofluorescence, and bound enzyme from a commercial cellulase cocktail supplemented with a small fraction of fluorescently labeled Trichoderma reseii Cel7A. Imaging was performed throughout hydrolysis at temperatures relevant to industrial processing (50°C). Enzyme bound predominantly to areas with low autofluorescence, where structure loss and lignin removal had occurred during pretreatment; this confirms the importance of these processes for successful hydrolysis. The overall shape of both untreated and pretreated hardwood and switchgrass particles showed little change during enzymatic hydrolysis beyond a drop in autofluorescence intensity. The permanence of shape along with a relatively constant bound enzyme signal throughout hydrolysis was similar to observations previously made for filter paper, and was consistent with a modeling geometry of a hollowing out cylinder with widening pores represented as infinite slits. Modeling estimates of available surface areas for pretreated biomass were consistent with previously reported experimental results. © 2014 Wiley Periodicals, Inc.

This paper analyses why and how design‐centred industrial firms with internal design teams contract external designers. This research is based on an exploratory multiple case study methodology, with a sample of five highly reputable design‐centred industrial firms, operating in hypercompetitive industries. While some results challenge the mainstream literature on design management, others expand the existing literature, highlighting that not all firms extract the same benefits from external designers; neither do all external designers bring the same benefits to firms. The paper shows that firms with internal design teams contract external design for (1) reputation (external designers sign products and bring their reputation to the product and to the firm), (2) perspective (external designers bring a different perspective, especially when they come from a different industry from the firm), and (3) exposure (external designers bring exposure that enriches internal design teams).

This paper completes the study presented in the accompanying paper, and demonstrates a numerical algorithm for parameter prediction from the piezocone test (CPTU) data. This part deals with a development of neural network (NN) models which are able to map multi-variable input data onto typical geotechnical characteristics and constitutive parameters of the modified Cam clay model, which has been applied in this study. The identification procedure is designed for the coupled hydro-mechanical boundary value problem in normally-and lightly overconsolidated clayey soils including partially drained conditions that may appear during cone penetration. The NN models are trained with pseudo-experimental measurements derived with the aid of the numerical model of the piezocone test, presented in the accompanying paper. Different input configurations containing CPTU measurements and some complementary data are studied with respect to the accuracy of predicted parameter values. Finally, the performance of the developed NN predictors is tested with field CPTU data which are derived from three well-documented characterization sites, and the obtained predictions are compared with benchmark laboratory results.

RATIONALE: The perfume market is growing significantly, and it is easy to find imitative fragrances of probably all types of perfume. Such imitative fragrances are usually of lower quality than the authentic ones, creating a possible threat for perfume companies. Therefore, it is important to develop efficient chemical analysis techniques to screen rapidly perfume samples. METHODS: Electrostatic-spray ionization (ESTASI) was used to analyze directly samples sprayed or deposited on different types of paper. A linear ion trap mass spectrometer was used to detect the ions produced by ESTASI with a modified extended transfer capillary for ’sniffing’ ions from the paper. RESULTS: Several commercial perfumes and a model perfume were analyzed by ESTASI-sniffing. The results obtained by paper ESTASI-MS of commercial fragrances were compared with those obtained from ESI-MS. In addition, a commercial fragrance was first nebulized on the hand and then soaked up by blotting paper, which was afterwards placed on an insulating plate for ESTASI-MS analysis. Analysis of peptides and proteins was also performed to show that the paper ESTASI-MS could be used for samples with very different molecular masses. CONCLUSIONS: Paper ESTASI-MS yields a rapid fingerprinting characterization of perfume fragrances, avoiding timeconsuming sample-preparation steps, and thereby performing a rapid screening in a few seconds.

Tubular space trusses for bridge applications use thick-walled tubes. The reduction in fatigue resistance due to geometrical size effects is thus an important issue. In order to carry out a thorough study, both fatigue tests on large-scale specimens and advanced 3D crack propagation modelling were carried out at ICOM/EPFL. The study is limited to circular hollow sections (CHS) K-joints. An alternate current potential drop (ACPD) system is used to measure crack depth on nodes of the tested truss specimens. The results obtained from the tests are given in the paper in terms of S-N data, crack depth versus number of cycles and deduced crack propagation rates. The numerical model was developed using the dual boundary elements method (DBEM), software BEASYTM, and was validated with fatigue tests data. The stress intensity factors (SIF) along the doubly curved crack front at different crack depths were obtained.With this model, a parametric study investigates the influence of geometry, size and load case on fatigue life. The results of both proportional and non-proportional sizing effects on fatigue strength are presented. The paper shows that size effects (proportional and non-proportional) can be expressed as a function of the non-dimensional parameters and chord thickness. Keywords: Structural steel, fatigue, size effects, large-scale tests, boundary element method.

Measures of signal complexity can be used to distinguish neurophysiological activation from noise in those neuroimaging techniques where we record variations of brain activity with time, e.g., fMRI, EEG, ERP. In this paper we explore a recently developed approach to calculate a quantitative measure of deterministic signal complexity and information content: The Renyi number. The Renyi number is by definition an entropy, i.e., a classically used measure of disorder in physical systems, and is calculated in this paper over the basis of the time frequency representation (TFRs) of the measured signals. When calculated in this form, the Renyi entropy (RE) indirectly characterizes the complexity of a signal by providing an approximate counting of the number of separated elementary atoms that compose the time series in the time frequency plane. In this sense, this measure conforms closely to our visual notion of complexity since low complexity values are obtained for signals formed by a small number of "components". The most remarkable properties of this measure are twofold: 1) It does not rely on assumptions about the time series such as stationarity or gaussianity and 2) No model of the neural process under study is required, e.g., no hemodynamic response model for fMRI. The method is illustrated in this paper using fMRI, intracranial ERPs and intracranial potentials estimated from scalp recorded ERPs through an inverse solution (ELECTRA). The main theoretical and practical drawbacks of this measure, especially its dependence of the selected TFR, are discussed. Also the capability of this approach to produce, with less restrictive hypothesis, results comparable to those obtained with more standard methods but is emphasized.

The distinct lattice spring model (DLSM) is a newly developed numerical tool for modeling rock dynamics problems, i.e. dynamic failure and wave propagation. In this paper, parallelization of DLSM is presented. With the development of parallel computing technologies in both hardware and software, parallelization of a code is becoming easier than before. There are many available choices now. In this paper, Open Multi-Processing (OpenMP) with multicore personal computer (PC) and message passing interface (MPI) with cluster are selected as the environments to parallelize DLSM. Performances of these parallel DLSM codes are tested on different computers. It is found that the parallel DLSM code with OpenMP can reach a maximum speed-up of 4.68x on a quad-core PC. The parallel DLSM code with MPI can achieve a speed-up of 40.886x when 256 CPUs are used on a cluster. At the end of this paper, a high-resolution model with four million particles, which is too big to handle by the serial code, is simulated by using the parallel DLSM code on a cluster. It is concluded that the parallelization of DLSM is successful.

This study presents a numerical approach designed for material parameter identification for the coupled hydro-mechanical boundary value problem (BVP) of the piezocone test (CPTU) in normally and lightly overconsolidated clayey soils. The study is presented in two related papers and it explores the possibility of using neural networks (NNs) to solve the complex inverse problem of the penetration test, including partially drained conditions. It has been demonstrated that the development of NN-based inverse models can be based on training data sets that consist of pseudo-experimental measurements derived from numerical simulations of the piezocone test. The first paper presents the development of the FE model of the studied problem, which can be used to generate a training data population corresponding to typical piezocone measurements that are obtained for clayey soils. The paper contains a detailed description of the numerical model with a sensitivity analysis with respect to different model parameters including the effect of partial drainage. The analysis also includes the model verification by means of a comparative analysis with numerical models of penetration proposed in the literature, as well as experimental evidence. Finally, owing to the loss of accuracy observed when applying a 'rough' frictional interface in the Updated Lagrangian formulation, an equivalent semi-numerical model for the piezocone test is proposed, taking into account a possible occurrence of partial drainage during penetration. Copyright (C) 2010 John Wiley & Sons, Ltd.

This paper presents a kite control and optimization problem intended as a benchmark problem for advanced control and optimization. We provide an entry point to this exciting renewable energy system for researchers in control and optimization methods looking for a realistic test bench, and/or a useful application case for their theory. The benchmark problem in this paper can be studied in simulation, and a complete Simulink model is provided to facilitate this. The simulated scenario, which reproduces many of the challenges presented by a real system, is based on experimental studies from the literature, industrial data and the authors’ own experience in experimental kite control. In particular, an experimentally validated wind turbulence model is included, which subjects the kite to realistic disturbances. The benchmark problem is that of controlling a kite such that the average line tension is maximized. Two different models are provided: A more comprehensive one is used to simulate the ’plant’, while a simpler ’model’ is used to design and implement control and optimization strategies. This way, uncertainty is present in the form of plant-model mismatch. The outputs of the plant are corrupted by measurement noise. The maximum achievable average line tension for the plant is calculated, which should facilitate the performance comparison of different algorithms. A simple control strategy is implemented on the plant and found to be quite sub-optimal, even if the free parameters of the algorithm are well tuned. An open question is whether or not more advanced control algorithms could do better.

This paper investigates the performance of spectral acceleration averaged over a period range (Saavg) as an intensity measure (IM) for estimating the collapse risk of structures subjected to earthquake loading. The performance of Saavg is evaluated using the following criteria: efficiency, sufficiency, the availability or ease of developing probabilistic seismic hazard information in terms of the IM and the variability of collapse risk estimates produced by the IM. Comparisons are also made between Saavg and the more traditional IM: spectral acceleration at the first-mode period of the structure (Sa(T1)). Though most previous studies have evaluated IMs using a relatively limited set of structures, this paper considers nearly 700 moment-resisting frame and shear wall structures of various heights to compare the efficiency and sufficiency of the IMs. The collapse risk estimates produced by Saavg and Sa(T1) are also compared, and the variability of the risk estimates is evaluated when different ground motion sets are used to assess the structural response. The results of this paper suggest that Saavg, when computed using an appropriate period range, is generally more efficient, more likely to be sufficient and provides more stable collapse risk estimates than Sa(T1). © 2015 John Wiley & Sons, Ltd.

Discoid lupus erythematosus (DLE) is an uncommon disease in childhood. In this paper we present five new cases of childhood DLE. Two of them are identical twin brothers, who developed similar lesions during an interval of 5 years. This is in favour of the hypothesis that both genetic factors and somatic mutations, due to environmental factors, are implicated in the pathogenesis. A review of the English language literature is also presented. In order to have better epidemiological data on this disease, all cases of childhood DLE, including those published in non-English literature and those not yet published, should be placed together and analysed.

This paper examines the spatial transformation of the city from children’s point of view. Three important daily living domains – children’s outdoor play spaces, leisure centres and caring institutions – are examined. Empirical findings are made from studies in Amsterdam, where new urban developments affecting children are most apparent in the Netherlands. Conclusions show that developments are both diverse and paradoxical. On the one hand, we see processes that progressively contribute towards the exclusion of children from urban public space. Safety considerations underpin these processes heavily. Children’s marginal position in the public domain is further reinforced in the planning and design of new residential areas. Children do not seem to be a factor that merits consideration. On the other hand, never before has so much attention been paid to children. Adults’ efforts to give due consideration to children’s position lead to the creation of many new domains especially created for children. These give children a ‘face’ in the city, but these spaces are characterised by privatisation, institutionalisation and segregation. In the context of the Netherlands it is not altogether clear what shape the future will take, but it seems to be most likely that indicated developments will continue.

Efficient implementation of closed-loop supply chains requires setting up appropriate logistics structures for the arising flows of used and recovered products. In this paper we consider logistics network design in a reverse logistics context. We present a generic facility location model and discuss differences with traditional logistics settings. Moreover, we use our model to analyze the impact of product return flows on logistics networks. We show that the influence of product recovery is very much context dependent. While product recovery may efficiently be integrated in existing logistics structures in many cases, other examples require a more comprehensive approach redesigning a company's logistics network in an integral way

[1] This paper shows how the Turkish-Iranian Plateau grows laterally by incrementally incorporating adjacent parts of the Zagros fold-and-thrust belt. The limit of significant, seismogenic, thrusting in the Zagros (Mw > 5) occurs close to the regional 1250 m elevation contour. The seismicity cutoff is not a significant bedrock geology boundary. Elevations increase northward, toward regional plateau elevations of ~2 km, implying that another process produced the extra elevation. Between the seismogenic limit of thrusting and the suture, this process is a plausibly ductile thickening of the basement, suggesting depth-dependent strain during compression. Similar depth-dependant crustal strain may explain why the Tibetan plateau has regional elevations ~1500 m greater than the elevation limit of seismogenic thrusting at its margins. We estimate ~68 km shortening across the Zagros Simply Folded Belt in the Fars region, and ~120 km total shortening of the Arabian plate. The Dezful Embayment is a low strain zone in the western Zagros. Deformation is more intense to its northeast, in the Bakhtyari Culmination. The orogenic taper (across strike topographic gradient) across the Dezful Embayment is 0.0004, and across the Bakhtyari Culmination, 0.022. Lateral plateau growth is more pronounced farther east (Fars), where a more uniform structure has a taper of ~0.010 up to elevations of ~1750 m. A >100 km wide region of the Zagros further northeast has a taper of 0.002 and is effectively part of the Turkish-Iranian Plateau. Internal drainage enhances plateau development but is not a pre-requisite. Aspects of the seismicity, structure, and geomorphology of the Zagros do not support critical taper models for fold-and-thrust belts.

This paper explores the potential for the concepts of time and space, together with the analogy of landscapes, to aid the exploration and understandings of women's careers. Drawing upon case studies of women who chose to opt in to self-employment, we examine how the multi-faceted histories of these women are drawn upon as they remember the past, explain contemporary experiences, and anticipate their futures. All the women spoke of opting in to self-employment as the best of times; they talked of greater control over work content, the relationship between family, gender and paid work, and self-determinism and autonomy. They noted times when their careers were frayed but only in retrospect could they assess the context, consequences and impact of events. The framework of careerscapes — our unique blending of the notion of careers along with socio-economic and geographical interpretations of scapes — offers a framework to examine frayed careers and multiple aspects of working and caring over time and space.

Applications of zero-inflated count data models have proliferated in health economics. However, zero-inflated Poisson or zero-inflated negative binomial maximum likelihood estimators are not robust to misspecification. This paper proposes Poisson quasi-likelihood estimators as an alternative. These estimators are consistent in the presence of excess zeros without having to specify the full distribution. The advantages of the Poisson quasi-likelihood approach are illustrated in a series of Monte Carlo simulations and in an application to the demand for health services.

Tuberculosis (TB), a chronic disease caused by infection with the Mycobacterium tuberculosis complex, is endemic in wild boar (Sus scrofa) and red deer (Cervus elaphus) in south-central Spain. Understanding the temporal dynamics of this chronic infection requires long time series data collection over large areas. The aim of this paper was to identify the determinants of TB prevalence and severity in both species in Ciudad Real province, Spain, from 2000 to 2012. Study variables included management, population dynamics, and a range of geographical and climatological factors. The prevalence of TB in wild boar increased from 50% to 63% since the study commenced. This may be due to an increased hunting bag (a proxy for population abundance), which was correlated with TB infection rates. Low rainfall (a stochastic factor) was associated with higher individual risk of TB presence and progression, resulting in an increased proportion of severe cases of wild boar TB in dry years. This was probably a result of increased food restriction leading to a higher susceptibility to TB. In contrast, red deer TB showed an apparent stable trend, which may be a consequence of the species' higher and stable population size. Hunting management, characterized by fencing, was associated with a higher risk of TB in both wild boar and red deer, suggesting that intensive hunting management may have contributed to exacerbated TB figures. This difference was more marked in red deer than in wild boar, probably because fencing imposes less restriction on movement, population mixing and TB spread to wild boar than to deer. Our findings on TB dynamics are fundamental for assessing the impact of future disease-control actions (e.g. field vaccination). Moreover, such control plans must operate in the long term and cover large areas., This study was funded by the MINECO research project AGL2010-20730-C02-01 and JCCM PPEII 10-0262-7673.This is also a contribution to EU FP7 EMIDA (ERA-NET) Grant APHAEA on wildlife disease surveillance in Europeand to FP7 Grants ANTIGONE (project number 278976) and WildTBVac. Jose Angel Barasona enjoyed a scholarshipfrom JCCM and a contract through MINECO Grant AGL2011-30041. We thank the Agriculture Department of JCCM and its Delegation in Ciudad Real for providing data on hunting statistics and sanitary campaigns. Pelayo Acevedo was supported by a Beatriu de Pinòs fellowship funded y ‘Comissionat per a Universitats i Recerca del Departament d’Innovaciò, Universitats i Empresa’ of the Generalitat de Catalunya, and the COFUND Programme–MarieCurie Actions under 7th Framework Programme of the European Community. He is currently funded from the SFRH/BPD/90320/2012 post-doctoral grant provided bythe Portuguese Fundaçao para a Ciencia e a Tecnologia (FCT) and the European Social Fund.

Whether animal vocalizations have the potential to communicate information regarding ongoing external events or objects has received considerable attention over the last four decades. Such ‘functionally referential signals’ (Macedonia & Evans 1993) have been shown to occur in a range of mammals and bird species and as a consequence have helped us understand the complexities that underlie animal communication, particularly how animals process and perceive their socio-ecological worlds. Here, we review the existing evidence for functionally referential signals in mammals according to the framework put forward in the seminal Macedonia and Evans review paper. Furthermore, we elucidate the ambiguities regarding the functionally referential framework that have become obvious over the last years. Finally, we highlight new potential areas for investigation within referential signalling. We conclude the functionally referential framework is still informative when interpreting the meaning of animal vocalizations but, based on emerging research, requires further integration with other approaches investigating animal vocal complexity to broaden its applicability.

Machine-to-machine networks are spreading over every sector of our society due to their self-organisation capabilities. In these networks, thousands of devices are left unattended for years of operation without the possibility of human intervention. In this sense, every step forward into avoiding early exhaustion of the network nodes is of paramount importance. We have introduced a novel authentication scheme that is able to discard non-intended and/or non-legitimate packets just after the reception of the physical preamble. This proposal was shown to yield enormous energy saving with regard to both node exhaustion attacks and normal network operation. In this paper, we extend that work with a novel synchronization protocol that addresses previous desynchronisation issues. Besides, we analyse and propose the more appropriate deployment parameters that maximise the overall energy savings. We also detail the necessary key generation and key updating processes required to manage the in use keying material. Moreover, we show how to fit the proposed mechanism into the IEEE 802.15.4e amendment to the IEEE 802.15.4-2006 standard, as many companies have decide to go for this technology for the development of machine-to-machine networks. © 2013 John Wiley & Sons, Ltd.

14 pages, 8 figures, 2 tables, Aim The emission of chlorofluorocarbon compounds eroded the ozone layer, raising incident ultraviolet B radiation to levels that affect biota. However, the role of UVB radiation (280–315 nm), which remains elevated to date, as a possible driver of the widespread global deterioration of marine ecosystems has not yet been fully quantified. In this paper we assess the magnitude of the impacts of elevated UVB radiation and evaluate the relative sensitivity to UVB across marine taxa and processes. Location The analyses presented are based on 1784 experimental assessments of the impacts of UVB performed with natural radiation and organisms from different geographical areas, as well as with artificial radiation and cultured organisms at many laboratories around the world. Methods First we compiled the published literature concerning experimental evaluation of the impacts of UVB on marine biota. Then a meta-analysis was conducted with the data set obtained to evaluate the responses of marine organisms and processes to enhanced and reduced UVB levels. Results Increased UVB radiation leads to a sharp increase in mortality rates across marine taxa, with protists, corals, crustaceans and fish eggs and larvae being most sensitive. A general relationship between relative changes in UVB doses and mortality rates was developed. This relationship can help assess the effects of changes in incident UVB radiation (past, present or future) on marine organisms. Main conclusions This meta-analysis demonstrates that mortality rates of marine biota increase rapidly in response to elevated UVB radiation. The enhanced mortality rates associated with currently elevated UVB levels may represent a major threat to marine biota, possibly underlying recent widespread declines in the abundance of marine organisms ranging from corals to fish and krill, This research is a contribution to the LINCGlobal programme (CSIC-PUC) and was partially funded by the Malaspina-2010 project of the CONSOLIDER programme (ref. CSD2008-00077) and the project MEDEICG (ref. CTM2009-07013) of the Spanish Ministry of Science and Innovation

Mango (Mangifera indica L.) stem bark extract (MSBE) is a natural product with biological properties and mangiferin is the major component. This paper reported the evaluation of the protective effects of MSBE and mangiferin against the toxicity induced in HepG2 cells by tert-butyl hydroperoxide or amiodarone.

Structural health monitoring of existing infrastructure is currently an active field of research, where elaborate experimental programs and advanced analytical methods are used in identifying the current state of health of critical structures. Change of static deflection as the indicator of damage is the simplest tool in a structural health monitoring scenario of bridges that is least exploited in damage identification strategies. In this paper, some simple and elegant equations based on loss of symmetry due to damage are derived and presented for identification of damage in a bridge girder modeled as a simply supported beam using changes in static deflections and dynamic parameters. A single contiguous and distributed damage, typical of reinforced or prestressed concrete structures, is assumed for the structure. The methodology is extended for a base-line-free as well as base-line-inclusive measurement. Measurement strategy involves application of loads only at two symmetric points one at a time and deflection measurements at those symmetric points as well as at the midspan of the beam. A laboratory-based experiment is used to validate the approach. Copyright (c) 2012 John Wiley & Sons, Ltd.

[Aim]: When faced with dichotomous events, such as the presence or absence of a species, discrimination capacity (the ability to separate the instances of presence from the instances of absence) is usually the only characteristic that is assessed in the evaluation of the performance of predictive models. Although neglected, calibration or reliability (how well the estimated probability of presence represents the observed proportion of presences) is another aspect of the performance of predictive models that provides important information. In this study, we explore how changes in the distribution of the probability of presence make discrimination capacity a context-dependent characteristic of models. For the first time, we explain the implications that ignoring the context dependence of discrimination can have in the interpretation of species distribution models. [Innovation]: In this paper we corroborate that, under a uniform distribution of the estimated probability of presence, a well-calibrated model will not attain high discrimination power and the value of the area under the curve will be 0.83. Under non-uniform distributions of the probability of presence, simulations show that a well-calibrated model can attain a broad range of discrimination values. These results illustrate that discrimination is a context-dependent property, i.e. it gives information about the performance of a certain algorithm in a certain data population. [Main conclusions]: In species distribution modelling, the discrimination capacity of a model is only meaningful for a certain species in a given geographic area and temporal snapshot. This is because the representativeness of the environmental domain changes with the geographical and temporal context, which unavoidably entails changes in the distribution of the probability of presence. Comparative studies that intend to generalize their results only based on the discrimination capacity of models may not be broadly extrapolated. Assessment of calibration is especially recommended when the models are intended to be transferred in time or space., The study was partially supported by projects CGL2009-11316/BOS-FEDER and CGL2011-25544. A.J.-V. was supported by the MEC Juan de la Cierva Program. P.A. was supported by the Vicerrectorado de Investigación of the University of Málaga. A.M.B. was supported by a post-doctoral fellowship from Fundação para a Ciência e aTecnologia (Portugal), co-financed by the European Social Fund. The ‘Rui Nabeiro’ Biodiversity Chair receives funding from Delta Cafés.

Understanding the factors that drive geographic variation in life history is an important challenge in evolutionary ecology. Here, we analyze what predicts geographic variation in life-history traits of the common lizard, Zootoca vivipara, which has the globally largest distribution range of all terrestrial reptile species. Variation in body size was predicted by differences in the length of activity season, while we found no effects of environmental temperature per se. Females experiencing relatively short activity season mature at a larger size and remain larger on average than females in populations with relatively long activity seasons. Interpopulation variation in fecundity was largely explained by mean body size of females and reproductive mode, with viviparous populations having larger clutch size than oviparous populations. Finally, body size-fecundity relationship differs between viviparous and oviparous populations, with relatively lower reproductive investment for a given body size in oviparous populations. While the phylogenetic signal was weak overall, the patterns of variation showed spatial effects, perhaps reflecting genetic divergence or geographic variation in additional biotic and abiotic factors. Our findings emphasize that time constraints imposed by the environment rather than ambient temperature play a major role in shaping life histories in the common lizard. This might be attributed to the fact that lizards can attain their preferred body temperature via behavioral thermoregulation across different thermal environments. Length of activity season, defining the maximum time available for lizards to maintain optimal performance, is thus the main environmental factor constraining growth rate and annual rates of mortality. Our results suggest that this factor may partly explain variation in the extent to which different taxa follow ecogeographic rules. © 2013 The Authors., We are grateful to G. Herczeg for sharing his unpublished data on SVL of the common lizards, Y. Surget-Groba for providing information about Zootoca vivipara haplotypes, and two anonymous reviewers, W. Jetz and A. Beckerman for comments on previous versions of this paper. This study was partially supported by the Grant Agency of the Slovak Republic VEGA (1/0491/10), the Spanish Ministry of Education and Science (CGL2005-01,187, CGL2008-01,522), the Swiss National Science Foundation (PPOOP3_128375), the Academy of Finland (Grant No. 108,955), and the European Science Foundation within the research networking “Thermal adaptation in ectotherms: Linking life history, physiology, behaviour and genetics” (EG/3312). TU is supported by the Royal Society of London.