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Introduction and Objective: Inflammatory bowel diseases (IBD) and anxiety, as well as depressive disorders, can coexist. Depression may affect IBD symptoms and vice versa. The aim of our study is to determine the impact of different classes of antidepressant medications in the treatment of IBD with comorbid depressive episodes, to summarize the most commonly used therapies, and to identify the most effective practices in treating inflammatory diseases with coexisting depressive episodes. Materials and Methods: A review of the available literature was conducted by searching the PubMed and Google Scholar databases using the following keywords: inflammatory bowel diseases, depression, antidepressants, in both English and Polish, up until July 19, 2024. To ensure the high quality of the narrative review, the SANRA scale (a scale for the quality assessment of narrative review articles) was used. Results: Studies indicate that depressive symptoms occur in approximately 25-27.5% of patients with inflammatory bowel diseases (IBD). Treatment of depression in IBD patients often includes the use of antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs), which not only reduce depression but also exhibit anti-inflammatory effects. SSRIs may also be effective in improving patients' quality of life; however, they may cause side effects such as diarrhea and an increased risk of bleeding. In addition to SSRIs, other antidepressants, such as serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and atypical antipsychotics, are also used and may have a beneficial impact on the course of the disease. Conclusions: In patients with IBD and comorbid depression, SSRIs are most commonly used, followed by TLPDs, SNRIs, and atypical antipsychotics. Drugs from these groups may have a beneficial effect on depressive symptoms, but also affect the course of IBD. Further clinical studies are needed to establish precise guidelines for the use of these drugs in patients with IBD.

Introduction Obesity is one of the major health problems of today’s population and is defined as a body mass index ≥ 30 kg/m2. It is known that obesity may cause many complications such as type 2 diabetes, cardiovascular disease, osteoarthritis, obstructive sleep, apnoea, and several cancers. The only effective treatment of obesity can be pharmacological or surgical, especially when a years-long attempt to change habits has had no effects. Aim of the study This review aims to present the current state of knowledge about non-pharmacological and pharmacological obesity treatment methods. Materials and methods The paper was created based on the Pubmed database. The literature was reviewed using the keywords: ”obesity”, ”obesity treatment”, “ obesity lifestyle changes”, “obesity medications” and ”obesity surgery”. The current state of knowledge The treatment of obesity requires a multimodal approach to treatment, including the addition of anti-obesity medications or bariatric surgery, or both, to assist people in reaching and sustaining sufficient weight loss to meet treatment goals. The 3 principal components of a comprehensive lifestyle intervention are diet, physical activity, and behavioral therapy. Among available anti-obesity medications include orlistat, phentermine, topiramate, naltrexone, bupropion, liraglutide, and semaglutide. Summary The key challenge in the treatment of obesity is to maintain the effects obtained with multimodal therapy. Without proper motivation of patients and changes in eating and behavioral habits, it is impossible to achieve optimal results, therefore, in addition to medical interventions, more and more attention should be paid to psychological interventions.

Introduction Polycystic ovary syndrome (PCOS), first described by Stein and Leventhal in 1935, is one of the most prevalent endocrine system conditions affecting women of reproductive age. It affects between 6% and 13% of women and the majority of cases are identified between the ages of 20 and 30. Unfortunately, the disease is usually diagnosed only when bothersome symptoms such as hair loss, alopecia, acne, and infertility-related problems occur. Based on the Rotterdam criteria, four phenotypes of PCOS are distinguished. Aim of the study This review aims to present the current state of knowledge about possible treatment approaches, both non-pharmacological and pharmacological. Materials and methods The paper was created based on the Pubmed database. The literature was reviewed using the keywords: ”PCOS”, ”PCOS treatment” and “ PCOS medications “. The current state of knowledge Treatments for PCOS must be tailored to the specific needs of each patient. In the management of PCOS, special attention is paid to diet, physical activity, and restoration of the Gut Microbiome. Medications used in therapy are oral contraceptives and anti-androgens, insulin sensitizers, ovulation inducers, calcium and vitamin D supplements, statins, Glucagon-like-peptide-1 (GLP-1) agonists, inositols and interleukin 22 (IL-22) therapy. Summary Treatment options for menstrual irregularities and hirsutism are based on the clinical goals and preferences of the patient. The ideal would be causal treatment, but due to the ongoing lack of full understanding of the pathogenesis of the syndrome, is not entirely feasible. The ideal would be causal treatment, but due to the ongoing lack of full understanding of the pathogenesis of the syndrome, is not entirely feasible. The most important is a multimodal approach to treat comorbid conditions such as diabetes mellitus type 2, obesity, hyperlipidemia, depression, and infertility.

This review explores the intricate relationship between dietary factors and lung cancer risk based on a thorough examination of relevant literature and articles. The findings highlight a significant association between specific dietary elements and lung cancer risk. Increased intake of fiber, fruit, and vitamin C is linked to a notable 9% reduction in risk, particularly for squamous cell carcinoma. Notably, vegetables exhibit a risk reduction for current smokers, while offal, red meat, and processed meat may elevate risk, especially in heavy smokers. Contradictory evidence surrounds dairy products, with fermented dairy inversely correlated. Beer and cider consumption are associated with an increased risk, primarily among current smokers. In contrast, avocados demonstrate a promising link to decreased lung cancer risk. Vitamin K intake shows an inverse relationship, particularly in males and ever smokers. High retinol intake may elevate risk, potentially modifying the effects of tobacco exposure. Nuts consumption is significantly linked to reduced lung cancer risk and overall cancer mortality. Dietary polyunsaturated fatty acids (PUFA) demonstrate a noteworthy risk reduction for lung cancer, with supplementation improving overall survival in patients with the disease. Palmitic acid, a component of saturated fatty acids, is implicated in promoting lung metastasis, emphasizing the intricate nature of dietary influences on cancer. In summary, while lung cancer is primarily associated with tobacco smoking, this review underscores the multifaceted interplay between diet and lung cancer risk. Further research is crucial to unravel underlying mechanisms and provide definitive evidence on the impact of specific dietary factors, emphasizing the importance of continued exploration in this complex field.

Introduction Ankylosing spondylitis (AS) is a chronic inflammatory disorder affecting the spine and joints, leading to significant physical impairment. With a prevalence of 0.1-1.4%, AS holds significance in healthcare and socioeconomic contexts, therefore a thorough understanding is crucial for diagnosis and effective management. This article provides a current state of knowledge of the subject for clinicians and patients. Review methods English-language scientific literature found in PubMed, Web of Science, Google Scholar and Wiley databases (2015-2023) was used for the review. Articles were searched based on keywords. Each article was analysed for knowledge currency and relevance for use in the review. Description of the State of Knowledge After searching the articles, 20 articles were selected for final analysis. The data collected provides the latest information on ankylosing spondylitis. The etiology of AS has a strong association with the HLA-B27 antigen and research is being conducted on the association with HLA-15, IL-1, IL-23R, ERAP-1 and ERAP-2. Clinical manifestations include a broad spectrum of symptoms involving the musculoskeletal, ocular, respiratory, cardiovascular, gastrointestinal and psychiatric systems. Specific diagnostic guidelines have been published by ASAS and EULAR. Treatment includes NSAID, GCS and biologic drug therapy. Summary AS, with its complex etiology and diverse clinical manifestations, presents a diagnostic challenge to clinicians. The variable prognosis and complex treatment in AS requires physicians to continually update their knowledge. Early diagnosis and treatment initiation can improve the patient's prognosis.

Introduction Menetrier's Disease is a rare and mysterious stomach disorder characterised by giant gastric folds, excessive mucus production, and protein loss. This comprehensive research article examines Menetrier's Disease, focusing on its clinical features, diagnosis, and available treatment options. The article aims to provide a complete understanding of Menetrier's Disease, fill the knowledge gap, and encourage improved clinical management. Description of the State of Knowledge Menetrier's Disease is a rare condition, and its cause is still unknown, though it may be linked to previous viral and bacterial infections and increased expression of transforming growth factor-alpha (TGF-α). Diagnosis can be established by endoscopic examination and histological analysis of material from a full-thickness mucosal biopsy. Treatment options are limited and concentrated on symptom relief, while the outcome of the therapy may vary. Summary Menetrier's Disease presents significant difficulties in both diagnosis and treatment. This review outlines the clinical features, classification, diagnostic approaches, available treatment options, and prognosis for healthcare professionals and researchers seeking to understand this disease better. Better understanding of Menetrier's Disease is crucial to improve patient care and explore new, potential therapeutic avenues.

Introduction : Hashimoto’s thyroiditis (HT) is the most common autoimmune disease and the leading cause of hypothyroidism in the world. The condition results in damage to the thyroid gland, brought about by the infiltration of lymphocytes. For the majority of individuals with Hashimoto's thyroiditis, a lifelong requirement for levothyroxine substitution is required. The potential contribution of diet and supplements to the management of HT is frequently overlooked. Low vitamin D levels are said to play a significant role in occurrence and severity of autoimmune thyroiditis. Currently, there is a continuing discussion regarding the optimal plasma concentration of 25-hydroxyvitamin D necessary for preventing or treating autoimmune diseases. Aim of the study : The purpose of this literature review is to evaluate the influence of vitamin D supplementation on the course of Hashimoto’s thyroiditis in the light of most up to date research. Materials and methods. This article is a review of publications obtained from the PubMed database, published between 2017-2023, based on the keywords "Hashimoto thyroiditis" "vitamin D" and "autoimmune thyroid disease". Conclusions. The correlation of vitamin D supplementation and Hashimoto’s disease still remains unclear due to conflicting results from numerous studies. Further research is necessary to accurately determine the effect of vitamin D supplementation on Hashimoto’s thyroiditis.

Cerebral edema, characterized by abnormal fluid accumulation in brain tissue leading to increased intracranial pressure, poses significant challenges for anesthesiologists. This review delves into the pathophysiology, clinical manifestations, diagnostic approaches, pharmacological strategies, and anesthesiological considerations associated with cerebral edema. Disruptions in the blood-brain barrier, alterations in cerebral blood flow, cellular swelling, and aquaporin dysregulation contribute to the complexity of cerebral edema. Clinical presentations vary, encompassing cognitive changes, seizures, and neurological deficits. Accurate diagnosis relies on clinical assessments and neuroimaging, with MRI and CT scans playing pivotal roles. Pharmacological interventions, including osmotic agents, corticosteroids, diuretics, and barbiturates, target specific causes and symptoms. Anesthesiological challenges encompass ICP monitoring, choice of anesthetic agents, maintenance of cerebral perfusion, fluid management, temperature control, and collaboration with neurosurgical teams. This multidisciplinary approach ensures optimal patient care and emphasizes ongoing research collaboration for refining therapeutic strategies. This comprehensive review provides valuable insights for clinicians managing cerebral edema, offering a roadmap for tailored interventions and highlighting the need for continued advancements in understanding and treating this critical condition. Material and method: ​​ The literature review applied standard criteria and focused on PubMed articles using keywords: cerebral edema, pathophysiology, aquaporin, blood-brain barrier, anesthesiology, cerebral edema treatment, corticosteroids

Introduction and purpose: Endometrial cancer [EC] is the most common gynecological cancer in developed countries and its incidence is increasing worldwide. Obesity is a prominent risk factor associated with its incidence and progression. The aim of study: The article aims to provide a thorough explanation of the mechanisms through which obesity can contribute to the development of EC. Additionally, it emphasizes the crucial role of combating excess adipose tissue as a significant component of cancer prevention specifically targeting endometrial cancer. Material and method: ​​The literature review applied standard criteria and focused on PubMed articles using keywords: Endometrial cancer, Obesity, Mortality, Prevention, Pathogenesis Description of the State of Knowledge: Obesity significantly impacts EC development and prognosis, particularly in Type I cases. It modifies adipose tissue metabolism, affecting the release of various substances linked to tumor growth and mortality risk.The relative risks escalate with increasing BMI. Following an EC diagnosis, higher BMI, especially ≥40, significantly associates with increased overall mortality risk. On a preventive front, exercise showcases its potential in reducing EC risk by moderating insulin and estrogen levels. Summary: These findings underscore the critical role of obesity in both EC development and prognosis, emphasizing the potential for preventive measures. Without proactive measures, the worldwide obesity epidemic will persist, exerting a substantial effect on EC occurrences.

Introduction and Purpose. Parkinson's disease (PD) is a progressive neurodegenerative disorder with characteristic motor symptoms and often overlooked non-motor manifestations, including dementia. This research article aims to enhance our understanding of PD and its complex clinical course, ultimately contributing to improved patient care and management. Moreover, it is important to raise awareness of cognitive impairment associated with Parkinson’s disease, as it is an aspect of social exclusion and disability Material and method. This study is based on medical articles collected from the PubMed database spanning the years 2015-2023. The research was conducted through the analysis of keywords such as Parkinson’s disease, dementia, diagnose, tremor, cognitive impairment. Brief description of the state of knowledge. Parkinson's disease is established as a movement disorder, primarily attributed to the loss of dopaminergic neurons in the substantia nigra. Although there is no cure for PD, treatment options have expanded, including pharmacological and non-pharmacological approaches. Early diagnosis is vital for effective management, and a multidisciplinary approach is crucial in addressing the diverse needs of PD patients. Summary. Parkinson's disease, a multifaceted neurodegenerative disorder, presents a complex clinical picture that extends beyond motor symptoms to include dementia. This review highlights the etiology, clinical manifestations, diagnostic criteria, differential diagnosis, various treatment modalities. Understanding of Parkinson’s disease, particularly its association with dementia, is essential for healthcare professionals and researchers to provide comprehensive care.

Introduction and purpose: Wine ingredients relevant to health are polyphenols, which are divided into flavonoids and non-flavonoids. Resveratrol is a non-flavonoid component of wine widely known for its health-promoting properties. This article will discuss its chemical structure, synthesis, metabolism, occurrence in nature and impact on human health. Review methods: The purpose of this article was to assemble and analyse the available data about resveratrol. The search of articles in Pubmed database was carried out using following keywords: “wine”, “resveratrol”, “polyphenols”, “alcohol”. Inclusion criteria: indexed in Pubmed database, published in last 10 years. Exclusion criteria: Case reports, studies in language other than English, studies that seemed to be biased. Descripiton of the state of knowledge: Resveratrol has a wide range of health-promoting effects. It inhibits some stages of platelet activation by reducing the synthesis of thromboxane A2 and their aggregation caused by agonists i.e. collagen, ADP, cathepsin G or thrombin. Furthermore, it causes a reduction in blood glucose and glycated hemoglobin levels, increases insulin sensitivity and potentially has protective effect on pancreatic cells. It lowers total plasma cholesterol and low-density lipoproteins levels while increasing insulin sensitivity and high-density lipoproteins level. In addition to this, it has neuroprotective, anti-tumour and anti-angiogenic effect proven in specific types of cancer. Summary: Resveratrol is said to improve the therapeutic outcome in patients suffering from cardiovascular diseases, diabetes type 2, Alzheimer's disease, other neurodegeneration diseases and in certain cancers. Nevertheless, the issue of resveratrol's effect on the human body requires further research.

Introduction and Purpose: Bruxism, the involuntary grinding or clenching of teeth, is a common problem in the adult population. This research aims to provide an overview of bruxism, focusing on its etiology, symptoms, diagnosis, and treatment, with the ultimate goal of enhancing understanding and promoting effective management strategies. Description of the State of Knowledge: Bruxism has been recognized as a prevalent dental disorder affecting a significant portion of the adult population. The condition involves the repetitive motion of grinding or clenching teeth, often occurring during sleep or subconsciously during waking hours. While its exact etiology remains multifactorial, stress, anxiety, malocclusion, and lifestyle factors are frequently implicated. The symptoms range from dental damage and jaw pain to headaches and disturbed sleep patterns, necessitating a comprehensive understanding of the disorder for accurate diagnosis and appropriate intervention. Current knowledge highlights the importance of early detection and tailored therapeutic approaches to alleviate symptoms and prevent complications. Summary: This article synthesizes existing knowledge on bruxism, addressing its etiological factors, clinical manifestations, diagnostic modalities, and available treatment options. By consolidating the state of knowledge, this research contributes to a more comprehensive understanding of bruxism and facilitates the development of evidence-based approaches for its management.

Introduction and purpose. Atopic dermatitis (AD) is a common chronic inflammatory skin disease that affects many children and adults around the world. It has been also empirically known that some environmental factors such as exposure to the sun can be beneficial for patients with AD. The purpose of this literature review is to present positive impact, as well as challenges and risks of heliotherapy and phototherapy on patients suffering from AD. Material and methods. The article is a review of publications obtained from the PubMed database and published between 2017-2023. Based on the keywords "phototherapy" "heliotherapy"and "atopic dermatitis", 14 articles were selected. Finally, 1 meta-analysis and 3 observational studies were included in the rewiev. Brief description of the state of knowledge. People with AD have a compromised skin barrier, which favors infiltration by activated Th2 cells, and their cytokine, causing thickening of the skin. It makes management of AD challenging. It is known that most patients’ skin condition improves due to sun exposure. This is why an artificial UV radiation (UVR) is employed for the treatment. The idea is to administrate a non-ionizing radiation to the skin. Both sunlight and artificial light have a significant immunosuppressive effect on the skin. Summary. Phototherapy as well as heliotherapy improved skin condition of people suffering from AD. It was appreciable by the end of few weeks of studies and also afer 3 months, reflected by improvement in PO-SCORAD, VAS and DLQI scales. During some of the studies there have been incidents of side-effects. More research is necessary to define a long-term effect of this kind of treatment and the role of chronic and prolonged therapy of AD.

Introduction: Medullary thyroid carcinoma is a primary thyroid neoplasm originating from thyroid C cells. It can be familial or sporadic. The familial form is associated with multiple endocrine neoplasia (MEN) syndrome types 2A and 2B and is caused by a mutation in the RET gene, which encodes a tyrosine kinase receptor. Treatment of medullary thyroid cancer is mainly based on surgical resection of the thyroid gland, usually a total thyroidectomy. It can be followed-up by a chemotherapy, which has limited efficacy. Hence, there is a growing interest in new molecular therapies, such as tyrosine kinase inhibitors, which include vandetanib, cabozantinib, selpercatinib, pralsetinib, sorafenib and lenvatinib. Objective: The review and presentation of the current state of knowledge on the systemic treatment of medullary thyroid cancer with kinase inhibitors. Material and methods: Literature review based on available sources from PubMed database and Google Scholar. Conclusions: Though systemic treatment options for medullary thyroid cancer continue to improve, patients with advanced neoplasms still have limited therapeutic options. Hence, further development of targeted treatment with kinase inhibitors, particularly those selective for the RET receptor is crucial. Molecular studies of mutations and signaling pathways involved in the oncopathogenesis of medullary thyroid cancer could contribute to the discovery of new therapeutic mechanisms, and drugs that target them, could potentially further improve disease progression-free survival (PFS) and overall survival (OS).

Introduction and purpose: Anxiety disorders are a heterogeneous cluster of common mental health disorders typically characterized by hyperarousal, excessive fear and worry. Unfortunately, a large portion of the world's population does not have access to traditional mental health care, this is influenced by the paucity of available psychiatric services, particularly in many low- and middle-income countries. This article will discuss how patients suffering from depression or anxiety disorders turn to non-pharmacological and unconventional interventions such as exercise, yoga, meditation, aromatherapy or music therapy. The aim of study: The purpose of this literature review was to assemble and analyse the available data about anxiety disorders. Material and method: Standard criteria were used to review the literature data. The search of articles in Pubmed database was carried out using following keywords: Anxiety disorders; depression; mental illness; alternative treatment methods. Description of the State of Knowledge: Pathologically increased anxiety is found not only in anxiety disorders per se, but also in most other types of mental illness. The first-line methods are pharmacotherapy and cognitive-behavioral therapy. Of particular interest is the use of physical activity and exercise in the treatment of anxiety disorders. This treatment is inexpensive and has few undesired effects. Exercises such as yoga, meditation, tai chi or qi gong are becoming more and more popular. Summary: Anxiety disorders can now be treated effectively. Current research focuses on individualized forms. We hope that even more effective methods of therapy will be developed than those currently available. Keywords: Anxiety disorders; depression; mental illness; alternative treatment methods.

Introduction: Particulate matter (PM) as a part of outdoor air pollutants are classified as human carcinogens. They are formed majorly as a result of combustion process by industry, power plants and engines. PM can be divided by the size of their particles into PM2.5 and PM10, where PM2.5 are small enough to penetrate into the alveoli sacs in the lung reaching the bloodstream, whereas PM10 affect mostly oral cavity, nose and the throat. Aim of the study: This study aims to investigate the impact of PM2.5 and PM10 particle concentrations in the EU NUTS 2 subregions on the death rates due to the most common malignant neoplasms. Results: There is a positive moderate correlation (r = 0.421; p < 0.001) between the annual mean concentration of PM2.5 and deaths due to malignant tumors. The strongest correlation was observed for malignant neoplasms of larynx, which is a positive correlation with a strong effect (r = 0.641; p < 0.001); and malignant neoplasm of bladder (r = 0.523; p < 0.001). For PM10, there is a moderately weak positive correlation (r = 0,195; p = 0.008) between the annual average concentration of PM10 and deaths due to malignant tumors. The strongest correlation was observed for malignant neoplasms of larynx, which is a positive correlation with a strong effect (r = 0,551; p < 0.001). Conclusion: The effect of PM impact on the malignant neoplasms is strong to moderate. The most affected neoplasm site are the ones the PMs intake occurs, being in the respiratory system. However other sites, where PMs can accumulate can be impacted as well. Further studies about the population with the highest risk due to the PMs exposure may be beneficial as other non-air quality-connected predictors may be found.

Mechanical traction of the lumbar spine remains a procedure very willingly used by therapists in many countries of the world, despite at least equivocal scientific evidence. One of the problems reducing its effectiveness is the problem with the selection of patients for therapy as well as selecting the therapeutic goals and treatment parameters for the patient in an individualized and, at the same time, repeatable manner. In this work, the authors presented such a model developed as part of Research and Development works carried out at the Leśny Dom Seniora in Piastów.

The aim of the study was to analyze the frequency of SEMG rectifier spine in children with scoliosis. Analysis electromyographic rectifier spine was performed using a 12-channel camera Noraxon TeleMyo DTS. The shape of the spine was assessed using optoelectronic Diers formetric III 4D. The research was Carried out in the Posturology Laboratory at the Faculty of Medicine and Health Sciences, UJK in Kielce (Poland). In the group of children with scoliosis curvature of the most frequently occurred on the location of the rib. In girls, it represented (62%) in boys (56%). In boys, thoracic scoliosis twoarched right-handed and left-sided lumbar were 19 (30%). The largest absolute differences in the frequency of EMG rectifier spine in girls with scoliosis group occurred lying ahead for the variable lumbar left (S = 36, 99). In turn, the value of the variable lower limbs up the right side of the lumbar was absolutely the most diverse among boys in the group of scoliosis (S = 40.54). Univariate analysis of variance indicated that there are significant differences in the measurements of intra-frequency variable SMEG rectifier spine torso upright thoracic among boys (p = 0.04). This means that the values of the variables were significantly different between groups attitudes scoliotic, scoliosis and normal boys, and the value of the significance level was less than 0.5 (p

Celem artykułu jest wykazanie, czy dyspozycje pracownika w postaci cechy charakteru i temperamentu R. Cloningera mogą sprzyjać skłonności do kształtowania pracy. Kształtowanie pracy1 jest zachowaniem polegającym na dokonywaniu zmian w zadaniach oraz relacjach w ramach wykonywanej przez siebie pracy. Badanie przeprowadzono wśród 162 pracowników z wykorzystaniem Kwestionariusza Temperamentu i Charakteru TCI-R (56) oraz Kwestionariusza Kształtowania Pracy – KKPracy. Zaprezentowane wyniki potwierdzają, że poziom kształtowania pracy jest zależny (R2=0,36) od unikania szkody (β=-0,39), uzależnienia od nagrody (β=0,32), samokierowania (β=-0,28), autotranscendencji (β=0,24) oraz skłonności do współpracy (β=0,15). Kształtowanie zadań jest objaśniane przez 24% zmiennych unikanie szkody (β=-0,42) oraz wytrwałość (β=0,16). Kształtowanie myślenia o pracy jest wyjaśniane w 22% przez autotranscendencję (β=0,39) i skłonność do współpracy (β=0,19), natomiast skłonność do kształtowania relacji interpersonalnych jest objaśniana w 22% przez uzależnienie od nagrody (β=0,40) oraz skłonność do współpracy (β=0,17).

The writings of Daniil Kharms and the philosophy of Henri Bergson In Daniil Kharms‘s writings there can be observed a significant convergence with Henri Bergson’s philosophical system. The concept of time found in the Russian vanguard artist’s works seems to be similar to that of Bergson. Kharms perceives time as a category of reality unknowable to the human mind. Time is bilinear: objective – as a category of physics, and subjective – as the time of human existence. Kharms also explores the problem of perception of reality and, like the French philosopher, distinguishes between two kinds of cognitive processes: the rational, external one and the intuitive one – getting to the core of the subject and enablingtrue cognizance. Bergson’s influences are also visible in Kharms’s concept of various states of consciousness, especially sleeping and falling asleep. In many works, Kharms expatiates on the subject of the artist, inspiration and masterpiece, approaching Bergson’s philosophy of creativity and genius. The French philosopher’s influence is discernible on the ideological level as well as in Kharms’s poetics. Shaping his ideas Kharms, like Bergson, is inspired by scientific achievements, while emphasizing the importance of the intuitive approach.

The aim of the study was to analyze the frequency of SEMG rectifier spine in children with scoliosis. Analysis electromyographic rectifier spine was performed using a 12-channel camera Noraxon TeleMyo DTS. The shape of the spine was assessed using optoelectronic Diers formetric III 4D. The research was Carried out in the Posturology Laboratory at the Faculty of Medicine and Health Sciences, UJK in Kielce (Poland). In the group of children with scoliosis curvature of the most frequently occurred on the location of the rib. In girls, it represented (62%) in boys (56%). In boys, thoracic scoliosis twoarched right-handed and left-sided lumbar were 19 (30%). The largest absolute differences in the frequency of EMG rectifier spine in girls with scoliosis group occurred lying ahead for the variable lumbar left (S = 36, 99). In turn, the value of the variable lower limbs up the right side of the lumbar was absolutely the most diverse among boys in the group of scoliosis (S = 40.54). Univariate analysis of variance indicated that there are significant differences in the measurements of intra-frequency variable SMEG rectifier spine torso upright thoracic among boys (p = 0.04). This means that the values of the variables were significantly different between groups attitudes scoliotic, scoliosis and normal boys, and the value of the significance level was less than 0.5 (p