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Aim of the Study: Analyzing the effectiveness of half-dose single treatment Photodynamic Therapy (PDT) which was implemented by using verteporfin in chronic central serous chorioretinopathy (CSCR) is the aim of this study. Material and Method: In this study, 34 patients'who have chronic CSCR 37 eyes were examined prospectively. Patients were given 3mg/m2 verteporfin and PTD was implemented to the areas where were identified in FFA and/or ICG by using the spot which is 1000 micron bigger than the active lesion's total diameter. Before and after the photodynamic therapy, in 1 week, 1 month and 6 month Central foveal thickness were measured by using full ophthalmoscopy and optical coherence tomography. The variation in Best Corrected Visual Acuity and Central Foveal Thickness is accepted as the criteria for effectiveness. Findings: This study focuses on 37 eyes of 34 patients who are 25 male and 9 female. The average age of patients is 48.5±8.4. The average follow-up time is 6.4±1.5 months. As a result of the Photodynamic therapy, it is observed that 51 %of patients had 2 rows or more visual recovery according to the Snellen visual acuity chart. While Best corrected visual acuity level were same for 27% of patients', 1 or more rows decrease were identified for 10% of patients. Before the photodynamic therapy, while the Central foveal thickness was 372.4±107.5 ?, after the photodynamic therapy the average central macular thickness was 220.97±76.4 ? (p

52 years female patient came to our clinic complaints with blurred vision and vision loss for the last few months. Visual acuity was detected 0.4 and 0.1 snellen scale at her right and left eye respectively. Slitlamp evaluation revealed normal anterior segments. Fundoscopic examination showed spotted atrophic areas and beaten egg-like appearance at the lower border of the round sharp macular lesion. Hyporeflective area was detected under the neurosensorial retina at RPE level with OCT in both eyes. With these clinical findings patient was diagnosed as adult onset vitelliform dystrophy. Any treatment wasn't applied to patient and he was called to follow properly. © 2016 Gazi Eye Foundation. All Rights Reserved.

Purpose: To determine the incidence of retinopathy of prematurity (ROP) in premature infants and to find out the risk factors that play a role in its development. Material and Materials and Method: 223 infants who were scanned and followed for retinopathy of prematurity at Ondokuz Mayis University, Faculty of Medicine between the dates January 2007 and August 2014 were included in the study. The data of the examinations were obtained from our clinic's archive while the patients' birth weights and comorbid systemic diseases were taken from patient files. Results: 446 eyes of 223 premature infants, 129 of whom were male (57.8%) and 94 of whom were female (42.2%), were examined in the study. Of the 223 infants, 138 (61.9%) were found to have ROP at any stage while ROP was not found in 85 (38.1%) infants. Of the risk factors examined in our study, birth weight, birth week, multiple pregnancy, respiratory distress syndrome (RDS), blood transfusion, sepsis, intraventricular hemorrhage (IVH), surfactant treatment, bronchopulmonary dysplasia (BPD) and patent ductus arteriosus (PDA) were found to be the risk factors that affected the incidence of ROP. In the multivariate regression analysis that was conducted, birth week, birth weight and intraventricular hemorrhage were found to play a role in the development of ROP as independent risk factors. Conclusion: Retinopathy of prematurity is a multifactorial disease. In our study, low birth weight, low gestation age and intraventricular hemorrhage were found to be the risk factors effective in the development of retinopathy of prematurity. © 2015 Gazi Eye Foundation. All rights reserved.

We aimed to present a patient with bilateral choroidal metastasis following bladder carcinoma due to its rarely occurence. A 56 years old male patient was consulted to our clinic complaining of blurred vision and vision loss. Best corrected vision acuity was measured as 0.3 in right eye and 0.6 in left eye. Fundus examination showed serous detachment in superior temporal quadrant including temporal edge of macula in right eye and in the inferior temporal quadrant of the left eye. Optic cohorence tomography showed a choridal mass elavating retina. In orbital MRIG an ellipsoidal mass with 10×5 mm size was detected in the posteriolateral part of the right globe. Methastasis in the lung and scalp tissue were detected with the patient who had been following for 3 years for bladder carcinoma. We speculated that choroidal mass and serous detachment could be owing to the metastasis of bladder carcinoma. Two weeks after the first dose of chemotherapy and radiotherapy patients died due to systemic metastases. Choroidal metastases are the most common intraocular tumours. Choroidal metastasis, secondary to urothelial carcinoma, is rarely seen and mostly effects individuals that are old and male. © 2016 Gazi Eye Foundation. All rights reserved.

35-year-old female patient came to our clinic with complaints of blurred vision and low vision. Her examination showed that optic disc of the left eye was normal and there were prevalent white lesions located in the deep layers of retina with more lesions at the macula temporal. Fundus fluorescein angiography (FFA) showed hyperfluorescence lesions in the early period and coloration in the later period. The findings brought multiple evanescent white dot syndrome to mind. No treatment was started and the patient's control a week later showed her vision at the level of 0.6 snellen scale. The examination four weeks later showed complete visual acuity and fundus examination was normal. © 2016 Gazi Eye Foundation. All Rights Reserved.

İnterferon (İNF) kronik hepatit B, C, metastatik renal karsinom, kutanöz melanom,kaposi sarkomu ve yeni doğanlardaki hemanjiomlarda kullanılan antiviral, antiproliferatif ve immünomodülatuar aktiviteyi düzenleyen bir ilaçtır. İNF alan hastalardaretinopati gelişme insidansı %18-86 arasındadır. Retinopati gelişmesi için başlıca riskfaktörleri yüksek doz INF tedavisi, diabetes mellitus ve hipertansiyondur. INFtedavisine bağlı gelişmiş retinopati genellikle iyi seyirlidir, görme kaybı ve diğer gözsemptomlarına yol açmaz. Fakat bizim olgumuzda retinopati büyük bir görmekaybına yol açmış ve 3 aylık takip sonrasında düzelmemiştir. Makalemizde 56yaşında, erkek, delta hepatiti nedeniyle yüksek doz interferon-alfa 2b tedavisi(Haftada 3 gün 10 milyon ünite) sırasında 17. ayda retinopati gelişen hastamızısunduk. Sonuç olarak; retinopati İNF tedavisi süresince gelişebilen akılda olmasıgereken bir komplikasyondur. Özellikle, yüksek risk grubundaki hastalar İNF tedavisiöncesinde mevcut olabilecek retinopati açısından değerlendirilmeli ve tedavi süresince retinopati gelişimi riski açısından üç aylık aralıklarla düzenli takip edilmelidir

Amaç: Akut gastroenteritler, hastaneye başvuru yakınmaları arasında sıklıkla yeralmakta ve tedavilerdeki gelişmelere rağmen yüksek mortalite ve morbidite oranlarıile seyretmeye devam etmektedir. Bu çalışmada Dokuz Eylül Üniversitesi TıpFakültesi Hastanesi Çocuk Acil polikliniğine akut ishal yakınması ile başvuran çocukolguların başvuru özelliklerinin değerlendirilmesi amaçlandı.Gereç ve yöntem: Dokuz Eylül Üniversitesi Tıp Fakültesi Hastanesi Çocuk Acilpolikliniğine akut ishal yakınması ile başvuran 541 olgu [291 (%53,8) erkek]retrospektif olarak değerlendirildi. Hastalar yaş, cinsiyet, dehidratasyon varlığı vederecesi, tedavi şekli ve süresi, komplikasyonların varlığı açısından araştırıldı. Bulgular: Hastaların başvuru anındaki yaşı ortalama 4,7 ± 4,1 yıl (1 ay-16 yaş,ortanca: 3 yaş) idi. Otuzüç hasta (%6) kanlı dışkılama, 508 hasta sulu dışkılamayakınması ile başvurdu. İshal süresi ortalama 2,0 ± 1,6 gün (min:1- maks: 9 gün),günde yapılan dışkı sayısı ise ortalama 5,2 ± 2,9 (min: 3- maks:15) idi. Hastaların %70’inde (383 hasta) kusma yakınması da mevcuttu. Hastaların 206’sı (%38,4)hastaneye başvurmadan önce antibiyotik kullanmaya başlamıştı. Hastaların %84’ünde(450 hasta) dehidratasyon yok iken, %16’sında (91 hasta) değişik derecelerdedehidratasyon mevcuttu. Onsekiz hasta (%3,3) hastaneye yatırıldı. Yatış nedenlerielektrolit imbalansı, ağır dehidratasyon ve asidoz, ağır kusma, konvulzyon geçirme veailenin sosyal endikasyonu idi. Dehidratasyonu olan hastalara oral veya parenteralyolla rehidratasyon tedavisi verildi. Akut ishal yakınması ile başvuran hastalararasında kaybedilen hasta olmadı. Sonuç: Çocuklarda akut gastroenteritlerin büyük çoğunluğunu viral gastroenteritleroluşturmaktadır. İshal tedavisinin en önemli komponenti dehidratasyonun tespiti vetedavisidir. Bu nedenle tüm hastalarda biyokimyasal incelemeler yapılmamalı,antibiyotik tedavisi gerektirecek özellikleri olmayan hastalara ampirik antibiyotiktedavisi başlanmamalıdır

Dokuz yaşında erkek hasta, sağ gözde bulanık görme ve sinek uçuşması yakınmalarıyla başvurduğu dış merkezde tek taraflı retinoblastom tanısı aldıktan ve ilk kür kemoterapisi uygulandıktan sonra merkezimize başvurmuştu. Ailede retinoblastom öyküsü pozitifti. Oftalmolojik incelemede görme keskinliği her iki gözde 10/10, bilateral ön segment muayenesi doğal, göz içi basınçları normal idi. Fundus incelemesinde; sağ gözde optik disk ve makula olağan, retina nazalinde vitreusa protrüze olan kitle ve inferiorunda birkaç odak, vitreusta yaygın tohumlanma görüldü. Sağ gözdeki retinoblastom “Reese-Ellsworth Grup Vb”, “Uluslararası Retinoblastom Sınıflaması Grup E” olarak değerlendirildi. Sol göz normal bulundu. Hastanın başka merkezde aldığı ilk kür kemoterapisinden sonra merkezimizde dört kür VEC (vinkristin, etoposid, karboplatin) kemoterapisi kemoredüksiyon amacıyla uygulandı. Kemoterapi ile sağ gözdeki kitlede ve vitreus tohumlanmasında gerileme olmadığı görüldü. Retinoblastomun lokal ilerleme ve sistemik metastaz yapma riski de göz önüne alınarak, ileri evreli, kemoterapiye yanıtsız retinoblastomu olan sağ göze, 10/10 görmesine karşın enükleasyon uygulandı. Lokal tedavi ile görme keskinliği ve globun korunması planlanan olguda, tümörde kemoredüksiyon rejimi ile tümör regresyonu sağlanamadığından enükleasyon uygulanmıştır

Objective: In this study, the influences of Mother Health and Child Care Training Program on expectant mothers' traditional belief and applications related to pregnancy, childbirth and puerperium have been researched. Material and Methods: In the research, both scanning and experimenting models have been used. While scanning model was used to define traditional belief and applications related to pregnancy, puerperium, the real experimental model with pre-test and post-test design was used to define the effects of traditional belief and applications of the training program. Among 64 pregnant individuals, 31 experimental from the sub-socio-cultural society and 33 from the control group, who could not take the benefits of the training sufficiently, were educated during 24-36 week-pregnancy period. In this study, the data were acquired first by applying "the Interview Form of Traditional Belief and Applications of Mother Health" (n= 196). Then, the "Scale of Traditional Belief and Applications in Mother Health" and "Success Test about Mother Health" were applied as pre-tests and post-tests. Results: 87.6 percent of the expectant mothers stated that they believed to become pregnant by drinking the mixture of different plants; 77% of mothers said by placing sugar, sugar, tar, and the cotton made out of herbs, spices and onions, etc., into the uterus, 78.2% said that they believed the baby would be beautiful if the pregnant lady stared at the beautiful people around. At the end of the training, a significant increase were recorded in the post test achievement scores of experimental group, and achievement test was found to be higher than the control group posttest mean scores (p=0.025). There was no significant difference among the mean scores of pretest/posttest AS-FOIU Attitude Scale in the control group (p=0.525). At the end of the training, it was observed that there were positive changes among mothers related to pregnancy, delivery, and puerperium, furthermore AS-FOIU posttest attitude scale means were found to be significantly higher than pretest scores (p