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The aim of this study is to examine neuroscience studies and experimental procedures in the existing management literature to contribute to the development potential of neuromanagement. Neuromanagement has emerged as a new field, introducing experimental data to the literature within management sciences. Following a literature review conducted through the "Scopus", "PubMed", "Emerald", "Springer" and "Web of Science" databases, articles were organized in the MENDELEY reference management system. The study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, and the review included 17 experimental studies meeting the specified inclusion and extraction criteria with available full texts or extended abstracts. Results indicate that experimental studies in neuromanagement predominantly focus on organizational and behavioral issues such as "Motivation," "Leadership," "Job Evaluation/Performance," "Stress," and "Morality." Neurological measurements (EEG, Skin Conductance Response, SCR, and Heart Rate) were commonly employed, particularly in the context of different leadership styles. In our country, despite systematic, descriptive, and biometric studies conducted in the field of management during the specified research period, no experimental studies have been identified. Recognizing this gap in obtaining empirical data in management, it is believed that encouraging future experimental studies will enrich the management literature. This approach offers researchers a distinct perspective on designing experimental studies based on the examined experimental procedures. [ABSTRACT FROM AUTHOR]

Objective: Obstructive sleep apnea syndrome (OSAS) increases the risk of cardiovascular disease. Autonomic dysfunction and inflammation are thought to play an important role in this increase. Heart rate variability (HRV) analysis provides noninvasive detection of autonomic dysfunction. The number and distribution of blood cells are also considered important markers of inflammation. In this study, HRV and hemogram parameters were examined in patients with OSAS, and the relationship between them was investigated. Materials and Methods: The data of all patients who had overnight polysomnography (PSG) recording and hemogram parameters between 2019 and 2021 were reviewed. HRV analysis was performed on all patients included in the study. Along with demographic and clinical characteristics, the relationship between PSG parameters, HRV, and hemogram parameters was statistically analyzed. The patients were divided into two groups as apnea hypopnea index (AHI) ≥15/hr and AHI<15/hr, and the parameters were compared. Results: A total of 321 patients (210 men, 111 women) were included in this study. The mean age was 54.8±16.1 years. The white blood cells count, hemoglobin level, hematocrit level, and neutrophil count, which are considered as indicators of inflammation, were significantly higher in the AHI ≥15/hr group (p=0.015; p=0.040; p=0.019 and p=0.012, respectively). Among the HRV parameters, the median low-frequency component power / high-frequency component power (LF/HF) ratio was 3.1 in patients with AHI>15/hr, while it was 2.1 in the AHI<15/hr group and was significantly higher in the moderate-severe OSAS group (p=0.012). A significant correlation was found between the LF/HF ratio and neutrophil count, leukocyte count, and neutrophil/lymphocyte ratio (r=0.201; p=0.005 and r=0.165; p=0.020 and r=0.189; p=0.008). Conclusion: In this study, the presence of increased inflammation and deterioration in sympathovagal balance in patients with OSAS has been demonstrated once again. The correlation of autonomic dysfunction with increased inflammation has been noted for the first time, suggesting that inflammation may play a primary role in sympathetic dysfunction, which is an important complication of OSAS. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Laboratory Animal Science & Practices / Laboratuvar Hayvanlari Bilimi ve Uygulamalari Dergisi is the property of Ataturk University Coordinatorship of Scientific Journals and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Karaelmas Science & Engineering Journal / Karaelmas Fen ve Mühendislik Dergisi is the property of Karaelmas Science & Engineering Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: To compare the lipid profile of preeclamptic pregnant women with the lipid profile of normal pregnant women. Materials and Methods: This study consisted of 40 severe preeclamptic, 40 mild preeclamptic, and 40 healthy pregnant patients who were prospectively admitted to the hospital in Harran University Faculty of Medicine, Department of Obstetrics and Gynecology between June 2021 and June 2022. Age, pregnancy and delivery numbers, blood pressure and pulse values, Body Mass Index (BMI), blood total cholesterol, LDL, HDL triglyceride (TG) levels and hemogram parameters (Hemoglobin, Hematocrit, WBC, Platelet count and MPV) of all patients were evaluated.he study was planned as descriptive cross-sectional. The attitudes of the students studying at the Faculty of medicine towards scientific research were questioned. In the study, the "Attitude Scale Towards Scientific Research" was used. Results: A statistically significant difference was found between systolic - diastolic blood pressures and heart rate values according to the groups (p<0.001 for all groups). It was found that the BMI of the pregnant women in the preeclampsia (PE) groups was higher than the control group and there was a significant difference between the BMIs according to the groups (p<0.001). It was determined that total cholesterol, TG and LDL values of pregnant women with preeclampsia were higher than healthy pregnant women, and HDL values were lower than healthy pregnant women (p<0.001). Conclusions: In this study, it was observed that the lipid profile in PE patients was higher than the lipid profile in normal pregnant women, and preeclamptic pregnant women were more obese. It was concluded that pregnant women with preeclampsia are a risky group in terms of lipid profile and should be followed up in the postpartum period. [ABSTRACT FROM AUTHOR]

Copyright of Nigde University Journal of Physical Education & Sport Sciences / Nigde Üniversitesi Beden Egitimi ve Spor Bilimleri Dergisi is the property of Journal of Physical Education & Sports Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of MN Cardiology / MN Kardiyoloji is the property of Medical Network and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of MN Cardiology / MN Kardiyoloji is the property of Medical Network and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The aim of this study was to investigate the short-term cardiovascular effects of medetomidine/ketamine (MED-KET) and xylazine/ketamine (XYZ-KET) anesthesia regimes and its reversal (atipamezole) in cats through using echocardiography. Twenty sexually intact female cats (weighing between 2.2 and 3.6 kg, and between 0.5 and 5.5 years of age) referred for ovariohysterectomy procedure. Electrocardiogram, noninvasive blood pressure, respiratory rate, heart rate and pulse oximetry were monitored throughout the anesthesia. Both groups showed declines in left ventricular diameter (LVD%) and left ventricular ejection fraction (EF) after anesthesia induction (T0 vs. T1, all, p<0.05); nevertheless, the reduction and starting pattern of LVD% and left ventricular EF presented important intergroup distinction. In conclusion, echocardiographic values effected significantly after anesthesia with MED-KET and XYZ-KET; and atipamezole can be useful for return to baseline values quickly and safely in cats after abdominal surgery such as ovariohysterectomy. [ABSTRACT FROM AUTHOR]

Copyright of Firat Universitesi Saglik Bilimleri Veteriner Dergisi is the property of Firat Universitesiu, Saglik Bilimleri Enstitusu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: The effects of laryngoscopy on hemodynamic response and intraocular pressure (IOP) are well known. The use of Supraglottic Airway Devices (SGAD) provides more stable hemodynamic parameters. Aim of this study is to compare the effects of laryngoscopic intubation on hemodynamic responses and IOP with intubation using Cobra Perilaryngeal Airway (Cobra-PLA) and Intubating Laryngeal Mask Airway (ILMA), without laryngoscopy. Methods: Sixty ASA I-II patients, without history of difficult intubation or ophtalmic pathology were randomly allocated into Cobra-PLA (G-PLA), ILMA (G-ILMA), and laryngoscopic intubation (G-L) groups. Induction was achieved with intravenous lidocaine 0.5 mg kg-1, propofol 1.5-2.5 mg kg-1 and rocuronium 0.6 mg kg-1. Propofol infusion of 2-4 mg kg-1 h-1 was continued until the 10th minute following intubation. Intubation was achieved by placing endotracheal tubes through the SGAD into the trachea in G-PLA and G-ILMA, and with a laryngoscope in G-L. Hemodynamic parameters and IOP were recorded before and after induction, the placement of SGAD, before and after intubation, extubation. Results: Demographic characteristics, mouth opening, thyromental distance, and Mallampati score of the groups were similar. Heart rate was significantly higher in G-L than the other groups after intubation (p<0.05). Mean arterial pressure increased with intubation and extubation in all groups, these changes were similar among groups. In comparison between groups, Mean IOP was found to be higher in G-L at the 1st, 2nd and 10th minutes after intubation compared to G-PLA and G-ILMA (p<0.05). Conclusion: It has been found that intubation without laryngoscopy with Cobra-PLA and ILMA cause similar hemodynamic response, especially intubation with Cobra-PLA leads to less IOP rise compared to laryngoscopic intubation. [ABSTRACT FROM AUTHOR]

Copyright of Karya Journal of Health Science is the property of Karya Journal of Health Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of SPORMETRE: The Journal of Physical Education & Sport Sciences / Beden Eğitimi ve Spor Bilimleri Dergisi is the property of SPORMETRE: The Journal of Physical Education & Sport Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: The aim of the study is to compare the hemodynamic and sedation results of patients who underwent anesthesia for electrical cardioversion (EC) during a one-year period in the coronary intensive care unit, retrospectively. Methods: 60 patients who were administered ketamine or fentanyl in addition to midazolam, which was administered EC for the correction of atrial fibrillation rhythm, were evaluated in terms of the study. According to the sedation applied to the patients, they were divided into two groups as Group F (midazolam-fentanyl) and Group K (midazolam-ketamine). The hemodynamic parameters of the groups before and after the procedure and the sedation data during and after the procedure were compared. Results: The pre-intervention heart rate of the patients was found to be high in Group-F (p<0.05). There was no significant difference between the two groups in terms of systolic and diastolic blood pressures (p>0.05). While heart rate was observed to be statistically higher after the intervention in midazolamfentanil applied patients, a statistically significant decrease was found in diastolic blood pressures (p<0.05). When Ramsay sedation scale was evaluated; There was no significant difference between the two groups at the 5th, 10th and 15th minutes (p>0.05). Conclusion: It was determined that the combination of midazolam + fentanyl or midzolam + ketamine provided adequate sedation at standard doses and had no adverse effects on hemodynamic and sedation parameters. These results made us think that both protocols can be safely applied for electrical cardioversion sedation in intensive care units. [ABSTRACT FROM AUTHOR]

Objective: Heart rate variability (HRV) consist of parameters which can be helpful for assesment of autonomic nervous system dynamics. Whilst it is known that HRV varies according to age and between genders; there is scant data regarding how the sex differences run its course with age. We aimed to evaluate variation of gender differences in HRV with age in healthy humans. Material and Methods: This study was based on retrospective analysis of the data recorded by 24-hours ambulatory Holter electrocardiograms of around 1,833 patients, who applied to Cardiology Policlinics in Eskişehir Osmangazi University from 01.01.2016 to 30.01.2018. 477 subjects, who were assessed as healthy humans and had over 20 hours of recordings, were included. Mean, minimum and maximum heart rate (HR), SDNN, SDNN index, rMSSD, pNN50, high frequency (HF), low frequency (LF), very low frequency values, LF/HF ratios of patients were noted. Groups according to age and genders were created and statistical analysis was performed subsequently. Results: Statistically significant difference was observed between the groups according to age in all HRV parameters (p<0.001). All parameters except mean HR, were lower in women compared to men. It was observed that the differences in terms of gender completely disappeared after the age of 60. Conclusion: In addition to lower HRV parameters in older age groups; it was also observed that the differences according to gender completely vanished after the age of 60 in our study. Autonomic regulation of the heart was detected under the control of the parasympathetic system in women; despite the higher HR and lower HRV parameters. [ABSTRACT FROM AUTHOR]

Copyright of Turkiye Klinikleri Journal of Sports Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of SPORMETRE: The Journal of Physical Education & Sport Sciences / Beden Eğitimi ve Spor Bilimleri Dergisi is the property of SPORMETRE: The Journal of Physical Education & Sport Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A 3-year old primipara Van cat weighing 2.7 kg, which had given a live fetus birth eight hours at home before being brought to our clinic at Erciyes University, Faculty of Veterinary Science, Education, Research and Practice Hospital, with a dark brown mass of about 2 cm width and 4 cm in length coming out of the vulva lips. The cat was examined clinically and diagnosed as uterine prolapse. It was evaluated that the cat's blood calcium level was low (6.6 mg/dl), probably causing uterine atony and uterine prolapse. In transabdominal ultrasonography examination, two pups with heart beats in the left corn uterus without prolapse were seen. After edema was reduced on the prolapsed right corn uterine, it was rejected into the vagina cavity. Immediately later, the cat was operated on under gas anesthesia. First of all, the offspring, one alive and the other dead (probably died during operation) were taken with the left corn incision. Then the eversion was corrected by pulling the prolapsed right corn uterus tip gently. Subsequently, an ovariohysterectomy operation was performed. After 10 days, the animal owner was called and it was learned that the mother and her offspring were healthy. After giving birth to a live fetus, the Van cat dystocia case with a corn uterine prolapse and the other corn uterine in the normal position (two live kittens inside) was seen in our clinic for the first time. [ABSTRACT FROM AUTHOR]

Copyright of Turkiye Klinikleri Archives of Lung is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Sports Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: The goal of this study was to examine the effect of keeping resting heart rate below 95 bpm on oxygenation, organ function, vasopressor need and mortality in sepsis and septic shock. Materials and Methods: Patients admitted to our intensive care unit with sepsis or septic shock diagnosis between June 2015 and July 2017 were included in the study. On the other hand, patients with a history of chronic β-blocker use, structural heart disease or permanent arrhythmia were excluded. After randomisation, patients in the study group (group BB) were given short-acting β1-blocker (esmolol) infusion to achieve resting heart rates between 85 and 95 bpm for 4 d. In both groups, 28-d mortality, vasopressor need and oxygenation parameters were recorded. Moreover, the results are presented as preliminary evaluation. Results: Fifty-two patients were included in the study. Further, 27 patients were in the group BB, while the remaining patients were in the control group (group NOBB). Pneumonia was the most common cause of sepsis (p>0.05). The APACHE II values in both groups were identical (p>0.05). Although the 28 d mortality rates decreased in the group BB, no statistical significance was observed due to insufficient sample size (p>0.05). The need for vasopressors also appeared to decrease on daily follow-up (p>0.05). In addition, the ratios of PaO2/FiO2 were higher in the group BB than in the group NOBB on day 3 (p<0.05). There was no difference in invasive mechanical ventilation, non-invasive mechanical ventilation, renal replacement therapy durations and length of stay (p>0.05). Also, no cardiac adverse effects associated with the intervention were observed. Conclusion: In this pilot study, we observed that cardio-selective β-adrenergic blockade could attenuate sepsis-related cardiac dysfunction. Decreased norepinephrine requirements and lactate levels, although not statistically significant, were consistent with a decrease in 28 d mortality rates. Despite enhanced oxygenation, mechanical ventilation durations did not vary in the group BB. In conclusion, we found that β1-receptor blockade had no detrimental effect on organ functions in sepsis. Moreover, it may be beneficial for cardiac and respiratory functions. [ABSTRACT FROM AUTHOR]

Objective: In this study, we aimed to investigate the effect of ultrasonograpy (USG) guided interscalene brachial plexus block on pulmonary functions and arterial blood gas analysis. Material and Method: The study was carried out with 64 patients who were planned to undergo shoulder and upper arm surgery and had no pulmonary dysfunction with ASA I-II and surgery time not exceeding 2 hours. USG-guided interscalene brachial plexus block procedure (baseline, T0) and 20 minutes after block (T20) was performed to provide anesthesia during surgery. Heart rate, systolic, diastolic and mean arterial pressure was recorded after block procedure. Spirometry and arterial blood gas analysis were performed to evaluate the effect of interschalen block on pulmonary functions and arterial blood gas. In addition, data related to block application were recorded. Results: A decrease in heart rate (p =0.003), systolic (p =0.375), diastolic (p =0.608) and mean arterial pressure (p =0.496) was observed at the 20th min (T20) after the block. In the second (T20) spirometric measurement performed at the 20th minute after block, compared to baseline (T0), vital capacity (VC) (4.86-3.68, p <0.001), forced vital capacity (FVC), forced expiratory volume 1.sec (FEV1) (4.24-3.40, p <0.018), Sniff PmaxPeak (6.18-5.06, p <0.001) and significant decrease in PaO2 (86.40-79.24, p <0,024) was observed. However, the average PaCO2 (38.62-42.34, p <0.001) increase was not significant. After the block, Horner syndrome findings were observed in 12 patients, and hypotension-bradycardia was observed in 6 patients. Hoarseness developed in 4 patients. Conclusion: Interscalene brachial plexus affects respiratory function and arterial oxygen pressure by causing unilateral hemidiaphragmatic paresis and is therefore risky for patients with pulmonary disease or cardiac pathology. [ABSTRACT FROM AUTHOR]

Objective: Postoperative pain is a condition that patients frequently complain about all over the world. The aim of this study was to investigate the effect of pain training before elective thoracotomy on postoperative pain levels in patients. Method: A total of 100 patients who underwent thoracotomy for any indication were included in the study. Patients were given a 20-30 minute training on postoperative pain and how the pain is controlled, and what the patient can do to minimize the pain 24-48 hours before thoracotomy. The patients were divided into two groups; those that were trained and those that were not trained on postoperative pain. Extubation time was accepted as baseline (0 hour). At the 4., 8., 12., 16., 20. and 24. hours, patients were asked to pinpoint their pain perception on the visual pain scale (VAS). Respiratory rate, blood pressure, heart rate, and oxygen saturation levels were recorded at same hours. Results: When VAS scores were compared between the two groups, no significant difference was found in the values measured at the 4th hour whereas there was a significant difference between the subsequent values. Conclusion: The results of this study showed that pain training before thoracotomy operation gradually decreased postoperative VAS pain scores in patients. [ABSTRACT FROM AUTHOR]

Copyright of Electronic Turkish Studies is the property of Electronic Turkish Studies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The present study was designed to examine the effects of high dose and low dose duloxetine on Cx43, a gap junction (GJ) protein; on S100A, cardiac contractility component and on certain early cardiac impairment parameters as TnI and TnT. Material and Methods: The study was performed with 24 male Wistar Albino rats by generating control group (1 ml solvent), low-dose duloxetine (LDD) group (10 mg/kg) and high-dose duloxetine (HDD) group (100 mg/kg). After the experimental procedure, the results concerning blood pressure and heart rates of the anesthetized rats were recorded and HE staining and immunostaining of Cx43, S100A, TnI and TnT were applied to the heart tissue sections. Results: In the control group, Cx43 was stained as marked streaks between cardiomyocytes; TnI, TnT and S100A were stained as homogenous and dark brown in cytoplasm. Nevertheless, intensity of Cx43 immunostaining showed significant increase in duloxetine-treated groups (p<0.001). TnT (p=0.024, p=0.004, p<0.05) and S100A (p<0.001) immunostaining were low in high dose group compared to control group and low dose group. TnI immunostaining also demonstrated significant decrease in high dose duloxetine group as compared to the control group (p<0.001). There was no statistically significant difference between groups in terms of heart rate, ECG parameters, MDA, SOD, GSH and CAT levels (p>0.05). Conclusion: Our study reveals that duloxetine induced an increase in the immunostaining of Cx43, and a decrease in the immunostaining of TnI, TnT and S100A, also known as early cardiac parameters. Furthermore, duloxetine was observed to show no effect on oxidant and antioxidant parameters. While heart rate remained unchanged, mean blood pressure decreased in high dose duloxetine group. In the light of the study outcomes, it has been concluded that antidepressants must be administered more advertently in depression patients with heart disorders. Bu çalışmada düşük ve yüksek doz duloksetinin, gap junction bileşenlerinden Cx43, kardiyak kontraktilite komponenti S100A ve kardiyak kasılma belirteci olarak kullanılan TnI ve TnT gibi erken kardiyak hasar parametreleri üzerindeki etkilerinin değerlendirilmesi amaçlanmaktadır. Gereç ve Yöntemler: Wistar Albino cinsi 24 adet erkek sıçan; kontrol (1 ml çözücü), düşük doz duloksetin (DDD) (10 mg/kg) ve yüksek doz duloksetin (YDD) (100 mg/kg) şeklinde üç gruba ayrıldı. Deney protokolü bitiminde anestezi altındaki sıçanların kan basıncı ile kalp hızı sonuçları kaydedildi ve elde edilen doku kesitlerine H-E boyama yöntemi, Cx43, S100A, TnI ve TnT immün boyama yöntemleri uygulandı. Bulgular: Kontrol grubunda Cx43 kardiyomiyositlerin bağlantı bölgelerinde belirgin çizgilenmeler şeklinde, TnI, TnT ve S100A ise sitoplazma içerisinde homojen ve koyu kahverengi olarak boyandı. Diğer yandan, duloksetin uygulanan gruplarda Cx43 immünreaktivite şiddetinde artış gözlendi (p<0,001). TnT (p=0,024, p=0,004 p<0,05) ve S100A (p<0,001) immünreaktivitesi yüksek doz duloksetin grubunda, kontrol ve düşük doz duloksetin grubuna göre daha azalmış olarak tespit edildi (p<0,001). TnI immünreaktivitesinin yüksek doz duloksetin grubunda, kontrol grubu ile karşılaştırıldığında azaldığı gözlendi (p<0,05). Ortalama kan basıncının doza bağlı olarak azaldığı diğer yandan kalp hızı, EKG parametreleri ve MDA, SOD, GSH ve CAT seviyelerinde gruplar arasında istatistiksel olarak anlamlı bir değişiklik olmadığı tespit edildi (p>0,05). Sonuç: Çalışmamız duloksetinin erken kardiyak hasar parametreleri olarak bilinen Cx43 immünoreaktivesinde artışa, TnI, TnT ve S100A'da ise azalmaya neden olduğunu gösterdi. Ayrıca oksidan-antioksidan parametreler ile kalp hızı üzerine herhangi bir değişikliğe neden olmadığı, ancak doza bağlı olarak ortalama kan basıncını azalttığı gözlendi. Bütün bunlar göz önüne alınarak, kalp rahatsızlığı olan depresyon hastalarında, antidepresanların da daha dikkatli uygulanması gerektiği sonucuna varıldı. [ABSTRACT FROM AUTHOR]

Background: Heart rate variability (HRV) is a noninvasive assessment that reflects the autonomic functions of the heart and it is known to be disrupted in many systematic diseases. In our study, we aimed to investigate the relationship between HRV and acute ischemic stroke (AIS). Materials and Methods: 102 AIS patients and 66 healthy individuals (control group) were included in the study. AIS patients were divided into two groups as ischemic stroke (IS) (n=65) and transient ischemic attack (TIA) (n=37). A 24-hour rhythm Holter record were applied to all patients. Results: The frequency of hypertension (60.8% vs. 33.3%, p=0.005) and diabetes mellitus (DM) (39.2% vs. 15.2%, p=0.002), and serum glucose (142.4±60.0 vs. 106.8±20.9, p=0.034) and creatinine levels (0.9±0.3 vs. 0.8±0.5, p=0.010) were significantly higher in AIS group, whereas serum high-density lipoprotein (44.7±9.7 vs. 54.6±12.9, p=0.022) and left ventricular ejection fraction (LVEF) values were lower (53.0 [25-60] vs. 58.0 [30- 60], p=0.012). Also, the HRV parameters SDNN (112.2 [37-1473] vs. 134.8[37-405], p<0.001), SDNN index (44.0 [14-132] vs. 55.1 [24-145], p<0.001), triangular index (1.5 [1-36] vs. 2.0 [1-53], p<0.001), HF (22.1 [5-2023] vs. 28.0 [13-2701], p=0.014), LF 2.7 [13-2367] vs. 3.4 [4-1523], p<0.001), and VLF 676.3 [7-1795] vs. 1014 [291- 1881], p<0.001) were lower in the AIS group. There was no significant difference between the TIA and IS groups in terms of basal characteristics and HRV (p>0.05, for all). In multivariable regression analysis, age (OR: 1.096, %95 CI: 1.056 -- 1.136, p<0.001), LVEF (OR: 0.362, % 95CI: 0.355-0.559, p=0.006) and DM (OR: 0.860, % 95CI: 0.856-0.931, p<0.001) were independent risk factors for AIS. Conclusion: In our study, we detected that HRV parameters were lower in patients with AIS. We also found that age, LVEF and DM were the independent risk factors for AIS. [ABSTRACT FROM AUTHOR]

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Copyright of Turkiye Klinikleri Journal of Sports Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Sports Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To compare the efficacy of paravertebral and epidural catheterization techniques which are used in post thoracotomy pain. Method: The records of 66 patients who underwent epidural (n=34) or paravertebral (n=32) catheterization and thoracotomy between January 2013 and January 2014 were evaluated retrospectively. Verbal Rating Scale (VRS) values and heart rate, blood pressure, respiratory rate, finger O2 saturation, severity of pain at rest and during cough at postoperative 0., 1., 4., 12. and 24. hours were recorded. Thoracic drain withdrawal times were recorded. Complications developed were recorded for each time point. Results: There was no statistically significant difference between the two groups in terms of age, sex, height and weight distribution. Considering hourly follow-ups, there were no statistically significant difference between the two groups. There was no statistically significant difference between both groups regarding the duration of the first additional analgesic administration, and complications. Conclusion: Since there is no significant difference between efficacies of paravertebral block and epidural catheterization, paravertebral block application can be an alternative method to epidural block because of lower number of complications, more reliable application and effective analgesia. [ABSTRACT FROM AUTHOR]

Objective: QRS amplitude attenuation and prolonged QRS duration has been associated with increased mortality in various clinical conditions including critical care patients and general population. Relative bradycardia has been found to be associated with lower mortality in patients with septic shock, but there are no studies in literature evaluating the electrocardiographic (ECG) changes and changes in heart rate (HR) just before death. Our aim of this study is to calculate the gradual changes in these parameters in the last hours of life from II derivation telemetry records. Material and Methods: We included 30 patients who died in intensive care unit irrespective of their diagnosis during admission and follow up. HR, QRS amplitude and QRS duration were analysed from the telemetry recordings obtained from the last 10 hours of their life. Results: QRS duration prolongs and heart rate decreases during the last 10 hours of life and the changes in these parameters were more prominent in the last hours. QRS duration increased at rate of 5.43 ms per hour (p<0.001) and heart rate decreased at rate of 2.68/min each hour (p<0.001). QRS amplitude attenuation were more subtle (decreased by 0.23 mV per hour, p=0.02) compared to QRS duration and heart rate. Conclusion: During last 10 hours of life, there was widening of QRS complex, attenuation of QRS voltage and decrease in heart rate. Automated softwares could present these findings in graphics and can be used as a prognostic indicators to recognize a dying patient. This information could be used in certain acute reversible critical conditions such as fulminant myocarditis, anaphylactic shock, trauma patients as a sign of poor prognosis or on decision making regarding end-of-life in irreversible illness such as terminal cancer patients. [ABSTRACT FROM AUTHOR]

Background: Changes in sleep duration and sleep disturbance have been reported to affect hypothalamicpituitary-adrenal axis (HPA) and the autonomic nervous system (ANS) activities. However, the effect of ANS activity on sleep parameters and HPA activity in the subsequent night and morning is not known. The aim of the current study, was, therefore, to assess the effects of heart rate varibility (HRV) on subsequent night sleep parameters and cortisol awakening response (CAR). Materials and Methods: Electrocardiographic recordings were carried out for 5 min for determination of HRV in healty medical students (n=48). They were allowed to sleep in their normal routines in following night. Sleep diaries were filled for sleep parameters (Karolinska Sleep Diary and Questionnaire). Salivary samples were taken at 0, 15, 30- and 60-min post-awakening for measurement of CAR. Cortisol concentrations were measured in the salivary samples by enzyme immunoassay. Correlations were carried out by Spearman Rho. p <0.05 values were considered significant. Results: The majority of the participants (80%) had time-domain variables within the normal range and they did not have sleep disturbances. Time- and frequency-domain parameters of HRV during the morning did not correlate with sleep parameters (time, duration, disturbed sleep, awakening problems) or CAR (mean, area under the curve) in the next day (p>0.05). Conclusion: The results of the current study suggest that, under the conditions which do not have profound effects on ANS activity, neither sleep parameters nor the next morning cortisol responses are affected by HRV. Additionally, a quality night sleep might counterbalance both the possible effects of previous days autonomic pressures and the next morning's cortisol responses. [ABSTRACT FROM AUTHOR]

Background: The purpose of the present study was to investigate autonomy nervous system activity during the menses and premenstrual period of the menstrual cycle using heart rate variability in women with prementstrual syndrome. Materials and methods: The study included volunteer women (n= 68), who were determined to have premenstrual symptoms according to the premenstrual syndrome diagnostic scale (ACOG), and who were between the ages of 18-30, students and assistants of Inonu University Medical Faculty. during the menses (1-3 days) and premenstrual (24-27 days) periods of the menstrual cycle, 5-minute ECG was taken and blood pressure measurements were made for one day heart rate variability analysis. In the statistical analysis of the data, normal distribution test was applied. Paired t test was used for repeated measurements of data providing normal distribution and Friedman test was used for analysis of data that did not provide normal distribution was used for the comparison of both phases of the menstrual cycle. p <0.05 values were accepted significant. Results: It was determined that time between two heartbeats and duration of QRS complex intervals, which are time dependent parameters, were statistically lower in premenstrual period than menses (p <0.05). High frequency (normalized) and % high frequency were statistically lower in the premenstrual period, while the frequency dependent parameters were statistically higher in the low frequency (normalized) and log low frequency/ high frequency premenstrual period than menses (p<0.05). Conclusion: Heart rate variability parameters reflecting sympathetic activity increased during the premenstrual period of the menstrual cycle. According to the findings changes in sympathetic activity may affect premenstrual symptoms to occur. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to examine the effect of preprocedural anxiety levels on developing complications and the effect of anxiety on perioperative vital parameters in patients scheduled for coronary angiography. Material and Methods: The study included 150 patients who were admitted to the cardiology outpatient clinic with chest pain and/or any complaints and who were indicated for coronary angiography for the first time as a result of examinations. Anxiety scores were evaluated using the Hamilton Anxiety Rating Scale. Increased blood pressure (>180/100 mmHg), increased heart rate (<120/min), hemodynamic collapse, vagotonia, hemorrhage and hematoma during and after the procedure were evaluated as complications. The patients were divided into two groups as Group 1 including 38 patients, the group with complications (27M; mean age 61.8±14.0 years), and Group 2 including 112 patients, the group without complications (69M; mean age 61.2±12.1years), according to whether or not complications developed. Results: Hamilton anxiety scores and procedure periods were significantly higher in Group 1 compared to Group 2. Blood pressures before and during the procedure and heart rates after the procedure were significantly higher in Group 1 compared to Group 2. Anxiety scores were significantly correlated with waiting periods and procedure periods. Anxiety scores were also significantly correlated with heart rates before and after the procedure. Conclusion: Anxiety scores were significantly higher in patients with complications. Effective anxiety treatment in patients whose preprocedural anxiety scores higher should be determined. [ABSTRACT FROM AUTHOR]

Copyright of Agri: Journal of the Turkish Society of Algology / Türk Algoloji (Ağrı) Derneği'nin Yayın Organıdır is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: CRBD is a condition that occurs commonly in postanesthetic patients who undergo intraoperative urinary catheterization. The aim of this study is to investigate and compare the effects of ketamine and tramadol on severity and incidence of CRBD. The patients that underwent elective percutaneous nephrolithotomy operations under general anesthesia were monitorized perioperatively. Material and Method: After induction of anaesthesia Foley urinary catheters were introduced. 20 minutes before extubation placebo (0.9% NaCl), 250 μg/kg ketamine IV and 1.5 mg/kg tramadol IV were administered to the patients in the group S, K and T, respectively. VAS (Visual Analogue Scale), arterial blood pressure, heart rate, saturation of arterial oxygen are assessed and recorded at 5, 10, 15 and 30 minutes postoperatively. Severity of CRBD and incidence of nausea are assessed and recorded by an observer who was blind to the study at 0, 1, 4 and 6 hours postoperatively. If VAS 3, 0.5-1 mg/kg meperidine IV were administered to the patients as an urgent analgesia. Patients with 3rd degree nausea and vomiting were given anti-emetic and 4 mg iv ondansetron. Results: In conclusion we have found that ketamine and tramadol which were given 20 minutes before extubation reduced the VAS and CRBD scores, and analgesic need in tramadol group was lesser than the other two groups. Conclusion: We think that in patients who undergo elective percutaneous nefroliotomy under general anesthesia tramadol is a safe and effective method which reduces severity and incidence of postoperative CRBD. [ABSTRACT FROM AUTHOR]

Purpose: The study was conducted to investigate the effect of nature-based sound therapy on patients during the separation from mechanical ventilator in a surgical intensive care unit. Materials and Methods: This randomized was controlled experimental study conducted with 64 patients. The patients was divided into two groups as experiment (n =34) and control (n =34) group. Before separating from the ventilator, the eyes in the experimental group were closed and 30 minutes of nature-based sound therapy was applied. Patients' arterial systolic and diastolic blood pressures, heart rate, respiratory counts, oxygen saturation values, pain at both 0th and 30th minutes before and after each interventions and the 0th, 10th, 20th and 30th minutes of seperation from the ventilator, and anxiety levels were compared. Data were collected by personal information form, survey form, Face Pain Scale, Glaskow Coma Scale, Modified Smiley Face Scale, and Richmond Agitation-Sedation Scale. Results: Clinical and statistically significant differences were found in the patients in the experimental and control groups for mean systolic and diastolic blood pressures, heart and respiration rates, administration methods and measurement times. Pain, agitation and anxiety levels of the experimental group were found clinically and significantly lower than the control group. Conclusion: Nature-based sound therapy applied in the process of separating the surgical patients from the intensive care unit from the mechanical ventilation support is effective in maintaining the arterial blood pressure, heart rate and respiratory rate in the normal range, and reducing the pain and anxiety. [ABSTRACT FROM AUTHOR]

Objective: The aim of the study was to compare the effects of intrathecal injections of levobupivacaine with bupivacaine on hemodynamic parameters, sensorial and motor block duration and side effects in adult patients undergoing lower extremity vascular surgery. Methods: After approval of our local ethics committee and the consent of the patients who will undergo lower extremity vascular surgery were obtained, 30 ASA I-III patients aged 25-75 years were randomly selected and included in two intrathecal injection study groups as follows: Group I (n=15) 17.5 mg (3.5 mL) isobaric 0.5% bupivacaine, Group II (n=15) 17.5 mg (3.5 mL) isobaric 0.5% levobupivacaine. All patients were administered 10 ml/kg lactate Ringer infusion and baseline values (T0) were recorded. After spinal anesthesia hemodynamic parameters were recorded at 2. (T1), 4. (T2), 10. (T3), 20. (T4), 30. (T5), 60. (T6) and 90. minutes (T7). In addition, side effects such as nausea, vomiting, itching, respiratory depression, hypotension, bradycardia, arrhythmia, convulsions, and tremors were recorded. Results: No significant difference was found between groups in terms of heart rate (HR), mean arterial pressure (MAP), and cardiac index (KI) parameters. The goups were similar in terms of sensorial block onset times and time elapsed till sensory block involved dermatomes, two-segment regression times and onset time of motor block. However, time to regression, and recovery from motor block was found to be shorter in Group II (p<0.05). None of the patients had ECG changes or side effects (p>0.05). Conclusion: Levobupivacaine, affects hemodinamic status in a similar way to bupicaine, it has been concluded with these findings that this drug may be used safely as local anesthetic in patients carrying cardiovascular disease potential. [ABSTRACT FROM AUTHOR]

Objective: Sacubitril/valsartan treatment has been shown to reduce the risk of hospitalization and mortality and to improve the quality of life in patients with symptomatic heart failure (HF) with reduced ejection fraction (HFrEF) compared to enalapril. To the best of our knowledge, no data have compared the ischemic and non-ischemic HRrEF groups in Turkey. This study comparatively investigated the effects of sacubitril/valsartan on clinical and laboratory findings in both ischemic and non-ischemic HF groups. Material and Methods: This study included patients with an indication for sacubitril/valsartan treatment initiation according to the HF guidelines. All patients underwent detailed histories, physical examinations, electrocardiograms, and laboratory tests, including sodium (Na), potassium (K), creatinine, and NT-proBNP, both before and 6 months after the treatment. We then compared the pre and post treatment findings. Results: A total of 127 patients (27.6% female), including 71 in the ischemic HF group and 56 in the non-ischemic HF group were enrolled the study. In both groups, systolic and diastolic blood pressures, heart rate per minute, NT-proBNP and sodium levels and weekly furosemide doses decreased significantly after sacubitril/valsartan treatment. While we observed no significant change in the glomerular filtration rate, we saw a statistically significant increase in creatinine and potassium levels. Conclusion: This study's results show the efficacy of sacubitril/valsartan in improving symptoms and cardiac biomarkers while reducing the need for diuretic therapy and heart rate in both ischemic and non-ischemic HFrEF patients. On the other hand, some complications (renal dysfunction, symptomatic hypotension and hyperkalemia) should be considered. [ABSTRACT FROM AUTHOR]

Aim: After spinal anesthesia, there are studies investigating the hypotension, ephedrine need and sensory block level according to the weight or abdominal circumference of the pregnant woman. Pregnant's weight or abdominal circumference is a rough description of the uterine content (the weight of the fetus, the weight of the placenta and amount of the amniotic fluid). The aim of this study was to investigate the relationship between weight of the fetus, weight of the placenta and amount of the amniotic fluid and the ephedrine need after spinal anesthesia. Material and Method: Fifty-one parturients who underwent cesarean section with spinal anesthesia were included in the study. 12.5 mg hyperbaric bupivacaine was injected into the subarachnoid space at the L3-4 intervertebral level. After spinal anesthesia, hypotension was defined as systolic blood pressure <100 mmHg or 30% decrease compared to baseline. Ephedrine (5 mg) was administered when hypotension was present. Bradycardia was defined as heart beat <60 beats / min. Atropine (0.5 mg) was made when bradycardia was present. Before spinal anesthesia and after spinal anesthesia, blood pressure values at 2, 5, 10, 20 and 30th minutes were recorded. At the end of the study, blood pressure variation, ephedrine and atropine requirement were evaluated according to fetus weight, placenta weight and amnion fluid amount. Result: No significant correlation was found between fetal weight, placenta weight, amniotic fluid index and ephedrine requirement (r = 0.063, p = 0.660; r = 0.093, p = 0.518; r = 0.162, p = 0.257, respectively). Conclusion: After spinal anesthesia, there are no relation between amount of the ephedrine used and fetal weight, placenta weight, amniotic fluid amount in pregnant women. [ABSTRACT FROM AUTHOR]

Mushroom poisoning is a frequently encountered health problem around the globe. Depending on its type and toxin, it results in a wide spectrum of issues that range from asymptomatic findings to fatal organ failure. Since the toxin of the mushroom leading to poisoning is often unidentified, syndromic classification may benefit clinical management according to the findings of target organ system toxicity. A 64-year-old female patient with comorbidities such as diabetes mellitus, coronary artery disease, hypertension and hyperlipidemia was admitted to the intensive care unit. Approximately four hours after consuming wild mushrooms the patient’s diarrhea, muscle cramps, cold sweating, blurry vision, coughing and shortness of breath complaints have been begun. Her respiratory system examination revealed tachypnea, generalized bilateral rhonchus, bronchorrhea and wheezing. Patient was normotensive and had bradycardia (heart rate 35 beats/minute). She had anxiety and the Glasgow Coma score was 15. Her pupillary bilateral isochoric, miotic and light reflexes were diminished. In her arterial blood gas pH level 7.26, partial carbon dioxide pressure: 34 mmHg, potassium: 5.3 mmol/L, sodium: 130 mmol/L, lactate: 5.3 mmol/L, bicarbonate: 16 mEq/L and base excess: -10,3 mmol/L was found. Target organ system toxicity findings and timing of occurrence indicated early-onset cholinergic syndrome. Treatments that consisted of intravenous atropine, fluid, electrolytes and sodium bicarbonate alleviated the toxicity in a short period of time. Late mycologic examination results that followed the treatment revealed that the patient was poisoned by Inocybe lacera, a mushroom type that contains muscarine. With this case presentation, we summarized the syndromic classification that we use in the clinical management in the light of current information in the literature. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study is to analyze the demographic characteristics, illness and healing process of mad honey intoxications in Düzce University Medicine Faculty Hospital Pediatric Emergency Department. Method: Patients admitted to Düzce University Medicine Faculty Hospital Pediatric Emergency Department, because of honey poisoning, between June 2012 and February 2015 were included in this retrospective study. It was planned to evaluate the effects of grayanotoxin intoxication in the pediatric age group. The demographic characteristics of patients, clinical findings and laboratory test results were collected from hospital records. We retrospectively examined records of the vital signs of patients and treatment they receive. Age, sex, toxicologic characteristics, heart rates, systolic and diastolic blood pressures of patients were analyzed. Results: Four cases were included in this study. The oldest patient was 16, the youngest patient was 2 years old. It was determined that patients had ingested mad honey, the average duration was 1.5 hours, before admitting to the emergency service. Patients' minimum heart rates were 41 to 63 bpm, systolic blood pressures ranged from 71 to 98 mmHg and diastolic blood pressures ranged from 27 to 41 mmHg. None of them had a chronic illness and drug use. Dizziness was observed in all patients. Two patients had bradycardia are quiring atropine were monitored. All patients received intravenous fluids support. Longest hospitalization duration was 4 days who had syncope, bradycardia with hypotension and oldest age of. Mortality and complication were not observed. Conclusion: Mad honey intoxication should be considered in cases without underlying disease, drug or substance abuse, trauma etc. history and presenting non-specific symptoms such as bradycardia, hypotension, gastrointestinal irritability, especially in the Black Sea region., The safe dose range is not certain so families should be advised to keep their children away from this honey. [ABSTRACT FROM AUTHOR]

Objective: In this study, the effects of calcium channel blockers, verapamil and diltiazem, were compared in preventing reflex cardiovascular effects caused by laryngoscopy and tracheal intubation. Material and Methods: Sixty patients were randomly divided into three groups: 1. group 0.1 mg kg verapamil, second group 0.3 mg kg diltiazem, third group 2 cc saline intravenous bolus. In terms of haemodynamic follow-up, changes in MAP, RPP and HR were evaluated in time. Results: Significant increases were observed in all three groups of patients in the HR until 4 minutes after intubation. No significant difference was observed between the 3 groups in terms of heart rhythm. Significant increases in MAP and RPP values after intubation were significantly inhibited in the verapamil and diltiazem groups. There was no significant difference in MAP and RPP values between verapamil and diltiazem groups. Conclusions: Verapamil and diltiazem did not significantly affect HR. Both drugs were determined to be effective in preventing increase of the mean arterial pressure and RPP, but there was no significant difference between them. Therefore, it is concluded that both drugs may be used to prevent hypertensive episodes, especially in patients with ischemic hypertensive patients, patients with increased intracranial pressure disease, and other conditions in which hemodynamic effects are not desired in response to intubation. [ABSTRACT FROM AUTHOR]

Objective: In this study, we aimed to investigate patient compliance and clinical success rates in patients undergoing NIV with AVAPS (Average Volume Assured Pressure Support) mode. Methods: Chronic Obstructive Pulmonary Disease patients (n:22) who were with hypercapnic respiratory insufficiency were given AVAPS mode. As initial parameters; IPAP Max 20 cm H2O, IPAP Min 12 cm H2O, Target Tidal volume=Ideal weight 6 ml/kg EPAP in AVAPS mode, starting with 5 cm H2O settings and increasing to the extent that the patient is tossed and SaO2≥90% . Arterial blood gas controls, pulse rate, respiratory rate and Borg dyspnea were measured at 1, 2, 8 and 24 hours after NMV adherence of the patients. Results: 72.7% (n:16) of 22 patients included in the study had a mean age of 70±10. 59% (n:13) of the patients had undetectable pH values within 24 hours. When PH, PCO2, PaO2/FiO2 and Borg dyspnea scores of patients before NIV and NIV application values of 1,2,8,24 hours PH, PCO2, PaO2/FiO2 and Borg dyspnea scores of patients were compared statistically, PH (p<0,001) and Pa02/FiO2 (p=0.002), PCO2 and Borg dyspnea scores were decreased (p<0.001, p<0.001), respectively. Significant changes were observed in all of the monitored parameters at 1 hour. No incompatibility was observed in any patient. As a result of service interventions, 95% (n:21) of the patients could be discharged home. Conclusion: It was observed that patient compliance and clinical success rates were higher in NIV application with AVAPS mode. [ABSTRACT FROM AUTHOR]

Objective: Nebulized beta agonists are being used in acute bronchiolitis treatment, but there is no consensus on the efficacy of this regimen. The purpose of this study was to investigate the electrocardiographic (ECG) effects of nebulized salbutamol in children with acute bronchiolitis. Materials and Methods: The study was conducted with 80 children aged 1 month to 2 years who presented to our pediatric emergency department (ED) with a diagnosis of acute bronchiolitis. Patients were randomly assigned to two groups equal in number. Group I was given one dose of nebulized salbutamol (0.15 mg/kg/dose) and Group II three consecutive doses of nebulized salbutamol (0.15 mg/ kg/dose) at 20-minute intervals. ECG measurements were assessed at the start of the ED visit and after nebulized salbutamol in both groups. Results: Baseline demographics of the two groups were similar. Heart rates were significantly higher in both groups after nebulized salbutamol in comparison to the initial evaluation.(Group I 155.25 vs. 166.35 beats/min; p=0.0001; Group II 158.20 vs. 166.05 beats/ min; p=0.009). PR intervals were also significantly shorter in both groups (Group I: 102 vs. 98 ms, p=0.013; Group II: 105 vs. 100 ms, p=0.001). The mean QTc intervals were longer in Group II patients compared to Group I after nebulized salbutamol (384.75 vs. 395.13 ms; p=0.031). There were no significant differences in the other electrocardiographic parameters between the two groups (p> 0.05). Conclusion: This study demonstrates that there were no differences in the ECG effects of single or three doses of nebulized salbutamol in children with acute bronchiolitis. However, salbutamol can cause Q-T interval prolongation after 3 doses. Therefore, we suggest that these patients should be considered for closer monitoring during administration of nebulized salbutamol. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Exercise Therapy & Rehabilitation is the property of Yavuz Yakut and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: We aimed to investigate the effect of ketamine-propofol combination (ketofol) in the different ratios on the hemodynamic parameters, recovery time, complications, and patient and doctor satisfaction in the cases underwent endoscopic colonoscopy. Methods: A total of 105 endoscopic colonoscopy patients who aged 18-65 and meet the criteria of American Society of Anesthesiologists (ASA) I-II were included in this randomized, controlled, double-blind study. Patients were divided into three separate groups: Group 1 consisted of the patients who administered 25 mg ketamine + 25 mg propofol, Group 2 included the patients who administered 25 mg ketamine + 50 mg propofol and Group 3 comprised the patients who administered 25 mg ketamine + 75 mg propofol . Each patient received intravenous 0, 2 ml/kg ketofol. Ramsay sedation scale (RSS) of >4 was expected during the procedure. In the patients with RSS of 4 or less, we administered an additional doses of ketofol about one four of initial dose. We recorded the heart rate, mean arterial pressure, arterial oxygen saturation, demographic data, administered drug dosage, sedation time, time for spontaneous eye opening and Modified Aldrete Scale (MAS) of >9, complications and patient-doctor satisfaction were recorded. Results: When comparing heart rate among the groups, the 10th min of heart rate was found higher in the Group 1 patients than that of others. There was no statistically significant difference in the other measurement times. While there was no significant difference in the 10, 15, 20 and 30 min of mean arterial pressure between the groups, the difference was statistically significant in the other measurement times. When we look at drug dosage, there was no difference in the induction dose between the groups, whereas total dose was lower in group 3 patients than the others. The time for spontaneous eye opening and MAS >9 after the procedure was found longer in the group 3 patients than the others. There was no statistically significant difference in the patient satisfaction among groups whereas doctor satisfaction was higher in the group 3 than group 1 and 2. Conclusion: The total drug dose decreased as the propofol ratio used in ketofol increased. Hence, the doctor satisfaction increased. On the other hand, the time for spontaneous eye opening and MAS >9 was increased. [ABSTRACT FROM AUTHOR]

Objective: Syncope is a common clinical problem in the general population. Vasovagal syncope (a type of neural -reflex syncope) is the most common form of syncope. The aim of this was to evaluate the electrocardiography and echocardiographic parameters in patients with vasovagal syncope Material and method: A total of 60 consequently patients with vasovagal syncopeand 30 randomly age/sex matched subjects with no cardiovascular or systemic disease were recruited in this study. Afterall study population underwent a detailed history and physical examination, the electrocardiography (ECG) and echocardiographic evaluation performed. Results: Vasovagal syncope group and control group were similar in terms ofthe age, sex, basic ECG and echocardiographic parameters (all p values >0.05).However, heart rate on ECG was significantly higher, while E/Em ratio was significantly lower in vasovagal syncope group (85±8,7vs77±6,9, p=0,033 ve 8,6±1,2 vs 9,2±1,1 p=0,020, respectively). Conclusion: In addition to reveal the possible underlying cardiac pathologyin syncope patients, the assessment of ECG and echocardiography can provide a usefulcontributionregardingleft ventricular filling pressure in patients with vasovagal syncope [ABSTRACT FROM AUTHOR]