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Introduction: Many studies conducted so far have shown that sleep has a great impact on physical and psychological health. In parenting, on the other hand, the sleep quality of the person deteriorates and problems such as depression and eating disorders may occur. In this study, it was aimed to shed light on the effects on the psychological and physical health of parents by examining the relationship between sleep quality and eating attitude and anxiety-depression of parents who have babies aged 0-24 months. Materials and Methods: This study was conducted prospectively on 260 parents who had babies aged 0-24 months, who applied to the Pediatrics Polyclinic of Kahramanmaraş Sütçü İmam University Medical Faculty Hospital between August-November 2019. A questionnaire including sociodemographic characteristics, Pittsburgh Sleep Quality Index (PUKI), Hospital Anxiety and Depression Scale (HAD), Eating Attitude Scale (EAS) were filled in by face-to-face interview method. Statistical analysis R 3.5.1. program and statistical significance level was accepted as p<0.05. Results: The mean PUKI score was significantly higher in women than in men (p<0.001). As the child's waking frequency increases, both the parent's PUKI score (p<0.001) and the frequency of poor sleep quality increase significantly (p=0.002). The frequency of poor sleep quality was significantly more common in women (69.3%) than men (46.3%) (p=0.002). There is a moderately positive correlation between the total PUKI score and the HAD depression score (r=0.41, p<0.001), and a strongly significant positive correlation between the total PUKI score and the HAD anxiety score (r=0.50, p<0.001). There is a strong and significant positive correlation between HAD depression and HAD anxiety score (r=0.64, p<0.001). There was a weak and positive correlation between HAD depression score and total EAS score (r=0.19, p=0.010). There is also a moderately significant positive correlation between HAD anxiety score and total EAS score (r=0.27, p<0.001). Conclusion: It should not be forgotten by every healthcare professional that not only mothers but also fathers are affected by the problems experienced in the postpartum period, and that parents should be followed up as well as the baby in the follow-up and management of this process in health services after birth. [ABSTRACT FROM AUTHOR]

Introduction: Urinary tract infection (UTI) is among the common bacterial infections in pediatric patients. These infections are more common in girls over one year old. This study aimed to investigate the bacterial distribution and drug resistance status in urine cultures of pediatric patients in our center. Materials and Methods: Urine culture results of patients who were presented to the outpatient clinics or were admitted to the Sivas Cumhuriyet University hospital between January 2017 and December 2022 were included in the study. The hospital automation system, patient files, and laboratory information management system were examined retrospectively. Statistical analysis was performed using the SPSS 22.0 software. A P-value of <0.05 was deemed significant. Results: Significant growth was observed in the urine cultures of a total of 1287 pediatric patients, 889 (69.1%) girls and 398 boys (30.9%). The patients included in the study were between the ages of 0-17, and children aged 1-6 (37.6%) were diagnosed with UTI more frequently than other ages. The most common UTI agent in the pediatric age group was Escherichia coli (56.6%). The first agent isolated in girls and boys is E.coli. Additionally, the prevalence of K. pneumoniae, P. mirabilis and K. oxytoca bacteria was higher in boys (p < 0.05). E. coli isolates showed minimal resistance to such as amikacin (0.6%), fosfomycin (1.0%), nitrofurantoin (1.4%), ertapenem (2.4%), imipenem (0.7%) and meropenem (0.9%). Conclusion: In this study, low resistance levels were detected for amikacin, fosfomycin, nitrofurantoin and carbapenem group antibiotics, which are important alternatives in the empirical treatment of UTI. On the other hand, due to the high resistance levels detected, it is thought that more caution should be exercised in the empirical use of amoxicillin-clavulanate, trimethoprimsulfamethoxazole and cefixime. If these antibiotics are to be preferred, waiting for the antibiogram results is an appropriate approach. [ABSTRACT FROM AUTHOR]

Introduction: To draw attention to possible causes of atypical radiological condition with a "secondary view" in atypical pediatric acute appendicitis cases. To offer solutions in order to minimize possible false negative ultrasonographic evaluation in atypical cases. Materials and Methods: 51 cases were included in this retrospective study. These cases were referred to our hospital because of an atypical acute appendicitis clinic, although ultrasonography was interpreted as normal in other centers in the last 24 hours. All cases were operated on with the diagnosis of acute appendicitis by "second look ultrasonography" performed in our department. Results: None of the cases had typical acute appendicitis clinic. Reasons such as perforation/plastron of the appendix, an atypical localization of the appendix, inflammation only in the distal part of the appendix, visualization of the appendix only with deep-compression, and failure to establish adequate communication with the patient for various reasons were conditions that could lead to atypical acute appendicitis and make imaging difficult. One or more of these were present in all cases. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to determine the relationship between school children's sleep problems and their nutrition habits and anthropometric measurements. Materials and Methods: This cross-sectional study was conducted with a sample of 484 children aged 7-14 years attending three primary schools and three secondary schools in the city center of Muğla province. Data were collected using the child data form and the child sleeping habit questionnaire. The obtained results were analyzed using Student's t-test, chi-square test, and Pearson correlation analysis. Results: It was determined that 72.9% of the children participating in this study had sleep problems, among which 83% of the underweight and normal weight children and 17% of the overweight and obese children had sleep problems. It was determined that children who ate or drank drinks in the last two hours before going to sleep had more sleep problems (p<0.05). There was a low level of positive and significant correlation between body mass index (BMI) and sleep duration and parasomnia, waist circumference and sleep duration, and neck circumference and sleep duration and parasomnia. Conclusion: In this study, no difference was found between the sleep problems of children who consumed healthy or unhealthy food, whereas those who ate close to sleep or consumed liquid had more sleep problems. While children's BMI, waist circumference and neck circumference increased, their sleep duration also increased. More parasomnia was observed in children with higher BMI and neck circumference. [ABSTRACT FROM AUTHOR]

Objective: This study determined the sleep hygiene level of senior undergraduate nursing students and to improve their sleep hygiene knowledge with an intervention program. Materials and Methods: This quasi-experimental study was conducted with 60 fourth-year nursing students who participated in the pre-test and posttest application of the research between January 9 and February 13 2023. Sleep hygiene education created by the researchers was applied to the control group with a traditional PowerPoint lecture and to the intervention group with a social media-supported message. Data were collected using the "student information form" developed by the researchers, the "Pittsburgh sleep quality index (PSQI)", and the "sleep hygiene index (SHI)". Percentage, mean, standard deviation, chi-square test were used in the evaluation of the data, and t-test in dependent groups was used in the evaluation of the dependent variables. Results: At the end of the pre-test and post-test of the study, an intergroup difference was found between the sleep hygiene of the students (p<0.05). In the in-group evaluations, it was determined that there was a significant decrease in the SHI post-test scores of the experimental group compared with the pre-test scores (t=3.35, p=0.002). In intragroup evaluations; there was a significant decrease in the PSQI scores of the experimental group (z=-3.152, p=0.002). Conclusion: The study found that both the sleep hygiene and sleep quality of the students were poor. The interventions used were found to be effective in improving sleep hygiene and quality. This research has shown that sleep hygiene, which is often overlooked, can be improved with the right interventions. [ABSTRACT FROM AUTHOR]

Objective: To examine the relationship between carpal tunnel syndrome (CTS) and sleep quality in different trimesters of pregnancy and to investigate whether there is a difference between trimesters in terms of sleep quality and CTS symptoms. Materials and Methods: This study was conducted between August 2021 and June 2022 at gynecology and obstetrics polyclinic. The sample of the study consisted of voluntary pregnant women between the ages of 18 and 45 years. Demographic data of pregnant women were evaluated with personal information form, sleep quality with Pittsburgh sleep quality index (PSQI), CTS symptoms with Boston carpal tunnel questionnaire (BCTQ), and grip strength with hand dynamometer. Kruskal-Wallis and Spearman correlation tests were used in the analyses. Results: The mean age of 219 pregnant women included in our study was 29.00±4.50 years, and the mean gestational age was 22.70±11.18 weeks. According to PSQI, 80.5% (n=177) of the pregnant women had poor sleep quality (≥5 points). When the trimesters were compared in terms of the evaluated parameters, a significant difference was found between the 1st and 2nd trimesters and the 2nd and 3rd trimesters among the subjective sleep quality sub-dimensions of PSQI (p=0.002). A positive correlation was found between BCTQ-Symptom and PSQI subjective sleep quality and PSQI daytime dysfunction, and a negative relationship was found between dominant handgrip strength (p<0.05). In addition, a positive correlation was found between the BCTQ-Function score and PSQI subjective sleep quality, sleep duration, and total scores, and a negative relationship was found between dominant hand grip strength (p<0.001). Conclusion: The sleep quality of pregnant women is low, and the presence of CTS has been confirmed as one of the reasons that reduce sleep quality. CTS symptoms during pregnancy negatively affect the sleep quality of pregnant women in the 1st and 3rd trimesters. [ABSTRACT FROM AUTHOR]

Objective: Although the tenofovir alafenamide/emtricitabine/bictegravir (TAF/FTC/BIC) regimen is recommended in national and international guidelines for changing treatment in treatment-experienced patients living with HIV (PLwHIV), there are limited real-life data reported in Türkiye. We aimed to evaluate the changes in virological and immunological indicators, renal functions, and lipid profiles in the follow-up of patients who switched to TAF/FTC/BIC. Methods: The study included treatment-experienced PLwHIV aged 18 years or older who were followed at the infectious diseases outpatient clinic between January 2020 and December 2021. Follow-up parameters before and after switching to TAF/FTC/BIC were evaluated retrospectively. Results: A total of 77 PLwHIV were included. Of those, 71 (92.2%) were male, and the median age was 42 years. The 24th and 48th week median HIV RNA values of patients whose viral loads were measured were 35 (27-77) copies/ml and 34 (24-49) copies/ml, respectively, after switching. We did not detected a significant difference in CD4+T lymphocyte count, CD4+ T lymphocyte percentage, and CD4+/CD8+ ratio when compared with pre-treatment values. Virological suppression was not maintained in 24.7% (n=19/77) of PLwHIV. While "incomplete virological response" was not detected in any patients, 2.6% (n=2/77) had virological rebound, 1.3% (n=1/77) were virological non-responders, 10.4% (n=8/77) had low-level viremia, and 20.8% (n=16/77) had virological blip. Glomerular filtration rate (GFR) (101 ml/min./1.73m² vs. 96 ml/min./1.73m², p=0.05) and total cholesterol level (199 mg/dl vs. 185 mg/dl, p=0.05) decreased at 48th week. In switching from tenofovir alafenamide/emtricitabine/elvitegravir/cobicistat (TAF/FTC/EVG/Cob) to TAF/FTC/BIC, significant decreases were detected in GFR (101 ml/min./1.73m² vs. 95 ml/min./1.73m², p=0.016) and total cholesterol levels (205 mg/dl vs. 182 mg/dl, p<0.001). Conclusion: Even if virological suppression is achieved before switching, virological suppression may be impaired in patients after switching to TAF/FTC/BIC. Moreover, renal functions should be closely monitored due to the significant decrease in GFR, especially when switching from TAF/FTC/EVG/Cob to TAF/FTC/BIC. [ABSTRACT FROM AUTHOR]

Objective: The study aimed to evaluate the clinical effects of levofloxacin (LEVO) and moxifloxacin (MOXI) prophylaxis during the treatment of acute myeloid leukemia (AML). Methods: This study had a prospective observational design and included AML patients who were scheduled for standard remission-induction (RI) or consolidation (C) chemotherapy. Prophylactic LEVO or MOXI was started at a ratio of 1:1 when neutropenia developed, and two groups were created. The primary endpoint was the frequency of febrile neutropenia (FN) and the time to FN. Results: 120 patients (60 patients in each group) were enrolled in the study. The frequency of FN tended to be higher in the LEVO group but was statistically insignificant (82.1% vs. 75.5%; p=0.702). The time to FN was 10.8±5.7 days and 10.1±5.7 days in the LEVO and MOXI groups, respectively (p=0.393). Microorganisms were izolated in 50.8% of patients who developed FN. The documented infection and bacteremia rate tended to be higher in the MOXI group (71.1% vs. 56.6%; p=0.331 and 87.5% vs. 80.5%; p=0.906). The rates of quinolone resistance were 69.2% and 75% in the LEVO and MOXI groups, respectively (p=0.451). The frequency of FN was higher during the RI phase than the C phase (89.1% vs. 70%; p=0.010). The frequency of documented infection was higher during the C phase than during the RI phase (77.1% vs. 49.1%; p=0.008). Conclusion: This study showed that prophylactic MOXI and LEVO have similar efficacy in AML patients. [ABSTRACT FROM AUTHOR]

Objective: C-reactive protein (CRP) is an acute-phase protein that is widely used and can be elevated in many conditions that lead to acute inflammation, including infectious diseases. In this study, we aimed to determine the rate of presence of an infectious disease in patients who were consulted because of a high CRP level. Methods: Inpatients and outpatients consulted to the Infectious Diseases and Clinical Microbiology (IHCM) Clinic between January and March 2022 because of high CRP levels were included in the study. The anamnesis, physical examination, and laboratory findings of the patients were recorded, and the existence of an infectious disease was investigated. Results: 124 patients were referred for consultation during the study period. CRP levels of 6 (4.9%) patients were within average reference values; the remaining 118 patients were included in the study. Of the 118 patients, 54 (45%) had clinical complaints consistent with an infectious disease. A focus of infection was detected in only 49 (42%) patients. We found that there was a significant relationship between the presence of symptoms consistent with an infectious disease and the presence of a positive physical examination finding with the presence of an infectious focus (p<0.05) Conclusion: In this study, we determined that more than half of the patients for whom consultation was requested due to high CRP levels did not have an infectious disease. We think that unnecessary consultation burden can be avoided by detailed clinical evaluation of the patients before referring them for consultation by only looking at the CRP results. [ABSTRACT FROM AUTHOR]

Objective: Identifying the presence and type of carbapenemases is essential to determine the treatment choices for carbapenem-resistant Gram-negative bacilli (CRB). Genotypic characterization of CRB needs technical support and experienced staff and is not an option for most laboratories due to its high cost. For this reason, especially in countries with limited resources, cheap, reliable phenotypic methods are an alternative, do not require experience, and can be easily applied in daily practice. The goal of the study was to evaluate the performance of phenotypic methods for carbapenemase production in CRB and to form a simple algorithm to differentiate carbapenemase types such as blaOXA-48 or blaNDM, which are common in our country. Methods: The study included 16 consecutive carbapenem-resistant, Gram-negative bacteria. Simplified carbapenem inactivation methods (sCIM) and modified Hodge test (MHT) were performed. Genes responsible for carbapenemase production (blaOXA-48, blaNDM, and blaKPC) were detected by real-time polymerase chain reaction. Temocillin resistance and ceftazidime-avibactam disc diffusion test were also applied to define carbapenemase types. Results: The carbapenemase gene was detected in 12 of the 16 strains; sCIM positivity was found in 11, and MHT was positive in 10. Sensitivity for sCIM and MHT were 91.9% and 83.3%, respectively. All Enterobacterales strains were positive for sCIM, and blaOXA-48 was the most common carbapenemase. sCIM false negativity was detected for only one strain. High-level temocillin resistance (MIC >128 μg/mL) was present in all strains with blaOXA-48; it wasn't detected in the strain carrying isolated blaNDM. Conclusion: sCIM positivity was present for all Enterobacterales, which were shown to carry the carbapenemase gene by RT-PCR. Our findings support the usage of sCIM in daily practice to screen for carbapenemase production in CRB. [ABSTRACT FROM AUTHOR]

Copyright of University of Health Sciences Journal of Nursing is the property of Saglik Bilimleri Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of University of Health Sciences Journal of Nursing is the property of Saglik Bilimleri Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of University of Health Sciences Journal of Nursing is the property of Saglik Bilimleri Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of University of Health Sciences Journal of Nursing is the property of Saglik Bilimleri Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of University of Health Sciences Journal of Nursing is the property of Saglik Bilimleri Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of University of Health Sciences Journal of Nursing is the property of Saglik Bilimleri Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of University of Health Sciences Journal of Nursing is the property of Saglik Bilimleri Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of University of Health Sciences Journal of Nursing is the property of Saglik Bilimleri Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Balikesir Health Sciences Journal / Balıkesir Sağlık Bilimleri Dergisi is the property of Balikesir Health Sciences Journal (BAUN Health Sci J) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food & Health (2602-2834) is the property of Scientific Web Journals (SWJ) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food & Health (2602-2834) is the property of Scientific Web Journals (SWJ) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: The aim of the study was to determine the unmet need for family planning and its causes in Şanlıurfa. Materials and Methods: The cross-sectional study was conducted with women of childbearing age who applied to family health centres in Şanlıurfa city centre and who did not use any family planning method. Cluster sampling method was used in sample selection and each family health centre was taken as a cluster. A pilot study was conducted to calculate the required number of clusters and the required number of clusters was found to be 16 and the study was completed with a total of 313 women. In the evaluation of the data, percentage, mean and standard deviation from descriptive statistics; Chi-square and Mann Whitney-U test from univariate analyses; Logistic Regression model from multivariate analyses were used. Results: In the study, it was determined that 35.5% of the women had unmet need for family planning (2.6% to interrupt their pregnancies, 32.9% because they did not want to get pregnant anymore). The most important factors that increase the unmet need for family planning are speaking Arabic at home 3.5 times, having 2 or more daughters 1.8 times, being 34 years of age or older 1.2 times, and having 30 months or more since the last birth 1.019 times (p<0.05). Conclusions: In the study, it was determined that the level of unmet need for family planning was approximately 3 times higher than the average of Turkey and that socio-demographic and cultural factors affected the unmet need for family planning. [ABSTRACT FROM AUTHOR]

Background: Motor Neuron Diseases (MNDs) are progressive neurological disorders characterized by the degeneration of upper and/or lower m otor neurons. T he t erm M ND includes Amyotrophic lateral sclerosis (ALS), Primary Lateral Sclerosis (PLS), Hereditary Spastic Paraparesis (HSP), Progressive Muscular Atrophy (PMA), Spinal Muscular Atrophy (SMA), Hirayama Disease, Kennedy Syndrome, Poliomyelitis and Postpolio syndrome (PPS). While both upper and lower motor neurons are involved in ALS, only upper motor neurons are involved in Primary Lateral Sclerosis (PLS), Hereditary Spastic Paraparesis (HSP), and only lower motor neurons are involved in Progressive Muscular Atrophy (PMA), Spinal Muscular Atrophy (SMA), Hirayama Disease, Kennedy Syndrome, Poliomyelitis and Postpolio syndrome (PPS). We aimed to investigate the clinical, demographic, and electrophysiological characteristics of MND patients who presented to our university hospital in Şanlıurfa province. Materials and Methods: 190 patients diagnosed and followed up with MND in the Neurology and Neuromuscular clinics and Electroneurophysiology laboratory were retrospectively analyzed from the medical records of patients between 2018 and 2023. 18 patients were excluded from the study because of insufficient file data. Patient data, including age, gender, presenting complaints, examination findings, family history, and electrophysiological features, were recorded. Results: Of the 172 patients included in our study, 103 were male and 69 were female. 54 patients were diagnosed with ALS, 3 with HSP, 2 with Kennedy syndrome, 21 with SMA, 4 with Hirayama disease, 82 with poliomyelitis sequelae, and 6 with PPS. Among the amyotrophic lateral sclerosis (ALS) patients, 22 were female and 32 were male. Fifteen patients had bulbar-onset symptoms, while 39 had spinal-onset symptoms. The initial symptom in 17 patients originated from the lower extremities; and in 22 patients, it started in the upper extremities. In 36 patients, ulnar nerve distal motor latencies (DML) were shorter than median nerve DML, and 24 of these patients had higher ulnar nerve compound muscle action potentials (CMAP) than median nerve CMAP. One of the 3 patients with HSP had a complicated type. Electromyography (EMG) of the tibialis anterior muscle in patients with sequelae of poliomyelitis revealed bilateral involvement in 55 patients and unilateral involvement in 7 patients. Slowing of conduction velocity was detected in 2 patients, and trap neuropathy i n t he m edian n erve w as observed i n 2 other patients. T he a verage a ge of 6 P PS patients w as 5 4.25±8.057. A mong t he patients diagnosed with Hirayama Disease, 1 was female, and 3 were male. Three patients were between 20-30 years old, while one of them was 58 years old. Myelomalacia at the C6-7 level was detected in the cervical imaging of one patient, and two patients had bilateral involvement without symptoms, while the other 2 had unilateral involvement. Conclusions: Recognizing the symptoms, signs, and risk factors of MND is crucial for physicians to facilitate early diagnosis. [ABSTRACT FROM AUTHOR]

Background: Acute appendicitis is the most common nonobstetric cause of acute abdomen in pregnant women. In this study, we aimed to evaluate pregnant patients who were operated on for acute appendicitis in our center, which has a large pregnant population, in the light of the literature. Materials and Methods: The data of patients operated on for acute appendicitis between November 2015 and August 2022 were retrospectively examined and recorded electronically. The patients' complaints, physical examination findings, radiological data, operation type, and pathological data were recorded and examined in the light of the literature. Results: The average age of 37 patients who underwent appendectomy was 27.7 (20-42) years. In these patients, acute appendicitis was diagnosed most frequently in the 2nd trimester (48.6%). The most common presenting complaint of the patients was abdominal pain, and the most common physical examination finding was abdominal tenderness. Considering the admission time of the patients, it was observed that a delay of more than 24 hours increased the risk of perforation. Although the most common histopathological finding was acute appendicitis, malignancy was detected in one patient and enterobius vermicularis was detected in another. Conclusions: Acute appendicitis should be kept in mind in patients with new-onset right lower quadrant abdominal pain during pregnancy. Because delay in diagnosis and therefore surgery causes serious morbidity and mortality for both the fetus and the mother. [ABSTRACT FROM AUTHOR]

Background: Hepatitis A virus is a self-limiting agent of acute viral hepatitis. It is responsible for 0.5% of viral hepatitis-related deaths worldwide. Hepatitis A is endemic in our country and its seroprevalence has been decreasing in recent years. Seroprevalence studies conducted on specific groups do not reflect the general population. This study aims to determine the seroprevalence of hepatitis A and to shed light on the need for hepatitis A vaccination. Materials and Methods: Patients who applied to primary health care institutions between 1 January 2019 and 31 December 2022 and for whom anti-HAV IgG and anti-HAV IgM tests were requested were included in the study. The data of the information management system of the Provincial Public Health Laboratory were evaluated retrospectively. Results: The number of cases analysed for anti-HAV IgM and anti-HAV IgG levels were 128,387 and 89,532 respectively. The number of anti-HAV IgM and anti-HAV IgG positive cases were 233 (0.18%) and 79,015 (88.25%), respectively. Of the 233 anti-HAV IgM positive cases, 41 (17.6%) were male and 192 (82.4%) were female. The incidence of acute hepatitis A infection in Gaziantep province was 0.18% and was highest in the 25-44 age group. In addition, there was a significant increase in the number of anti-HAV IgM positive cases in June 2021 and May, June, September and October 2022 compared to other months. Conclusions: Although hepatitis A infection has decreased in our country, it still remains a public health problem. The incidence of acute hepatitis A infection in Gaziantep province is 0.18%. This rate is higher than the incidence in our country. In our study, it was determined that acute hepatitis A infection poses a risk in adults. Therefore, seronegative adults should be vaccinated. In our opinion, hepatitis A vaccine should be included in the adult vaccination programme. [ABSTRACT FROM AUTHOR]

Background: Background: In acute pancreatitis (AP), determining the severity of the disease starting from hospitalization is important for planning the treatment. Data obtained in previous studies that examining the clinical importance of RDW (Erythrocyte Distribution Volume) and MPV (Mean Platelet Volume) levels in patients with AP are contradictory. Our aim in this study is to determine whether RDW and MPV levels can predict the severity of pancreatitis and related mortality. Materials and Methods: The data of 262 patients hospitalized due to AP between 2019 and 2022 were retrospectively examined. Patients were divided into groups according to Atlanta criteria.Then, the relationship between RDW and MPV values and the severity and prognosis of pancreatitis was examined statistically. Results: While 83.9% (n=220) of the patients had mild pancreatitis, 16.1% (n=42) had severe pancreatitis. While the mean RDW index was 42.5±6.9 fL in patients with mild AP, it was 42.0±6.6 fL in severe AP patients and there was no significant difference between the two groups (p=0.625). In addition, there was no significant difference between the two groups in terms of mean MPV level (9.7±1.0 fL vs 9.8±1.3 Fl, p=0.687). ROC analysis showed that there was no significant and critical MPV and RDW threshold value to detect the severity of pancreatitis (AUC values: 0.499 and 0.453, respectively). Conclusions: In our study, we found that there was no significant difference in terms of RDW and MPV in patients with mild and severe pancreatitis according to the Atlanta criteria. Therefore, we can say that MPV and RDW levels are not sufficient and strong parameters to predict the severity and prognosis of pancreatitis. [ABSTRACT FROM AUTHOR]

Objective: Central nervous system (CNS) infections are a significant cause of mortality and morbidity all over the world. Currently, molecular methods with high sensitivity and specificity provide a diagnosis from a small amount of cerebrospinal fluid (CSF) sample in a short time. Our study aims to determine whether the meningitis/encephalitis panel test is used rationally and to make appropriate recommendations for practical use in the approach to CNS infections. Methods: Between January 2022 and 2023, 46 samples with meningitis/encephalitis panel requests were included in the study. Cerebrospinal fluid samples of the patients were studied with the QIAstat-Dx Analyzer (Qiagen, Hilden, Germany )and the QIAstat-Dx® Meningitis/Encephalitis (ME) Panel kiti (Qiagen, Hilden, Germany). Data about age, gender, CSF leukocyte, erythrocyte, glucose and protein, blood leukocytes and C-reactive protein (CRP) values, presence of fever, headache, neck stiffness, and altered consciousness in patients were obtained retrospectively from patient files and the hospital information system. Results: Of the 46 patients, 22 were female and 24 were male. Three Varicella-zoster virus, two Herpes simplex virus-1, two Cryptococcus neoformans/gatti, one Escherichia coli K1 and one Listeria monocytogenes positivity were detected in the ME panel of a total of nine samples, five from female and four male patients; the total positivity rate was 19.5%. CSF leukocyte and erythrocyte value, blurred consciousness, blood leukocyte count, and CRP values did not differ significantly between panel (-) and panel (+) groups. Fever, headache, nuchal rigidity, high CSF protein, and low CSF glucose were very different in the group with panel (+) (p<0.05). Conclusion: Requesting an ME panel with a rational algorithm after microbiological and biochemical evaluation of CSF samples taken with a strong clinical suspicion will be convenient and cost-effective, prevent unnecessary antibiotic or antiviral use, and reduce hospital stays. [ABSTRACT FROM AUTHOR]

Introduction: The increase in antibiotic resistance due to overuse and misuse has led to changes in the primary pathogens causing otitis media and antibiotic susceptibility. Empirical antibiotic treatment may cause treatment failure or result in complications in diseases caused by antibiotic-resistant bacteria. We aimed to identify bacterial pathogens associated with ear infections and to evaluate antibacterial resistance among isolated organisms. Methods: Ear swab samples of patients who applied to our hospital's Ear Nose and Throat Outpatient Clinic between February 2022 and February 2023, sent to our laboratory with the preliminary diagnosis of ear infection, were examined. The study included 144 patients whose ear swab samples' Gram staining and culture results were compatible with ear infection. Microorganisms that grew in culture were identified using conventional methods. The antimicrobial susceptibility of the isolated strains was determined using the Kirby-Bauer disk diffusion method and evaluated by the European Committee on Antimicrobial Susceptibility Testing (EUCAST) criteria. Results: The study examined 171 external ear canal culture results from 144 patients at their first admission and 19 patients due to recurrent external ear canal discharge in later periods. Pathogenic microorganism growth was observed in 90 specimens, normal microbial flora grew in 58 specimens, and no microorganism growth was observed in 23 specimens. Staphylococcus aureus was the most common, and Pseudomonas aeruginosa was the second most common pathogen. Ampicillin resistance was the highest among the isolated Gram-negative bacteria (77.7%). Conclusion: It is essential to monitor the frequency of causative pathogens and the rates of resistance to antimicrobial agents to start appropriate antimicrobial therapy in patients with ear infections. [ABSTRACT FROM AUTHOR]

Objective: This study aimed to determine the measles seroprevalence and related factors in healthcare professionals working in units with a high risk of encountering measles cases in Dokuz Eylül University Hospital. Methods: This cross-sectional study was conducted between June 2018 and September 2019. The study population consisted of all healthcare professionals working as specialist doctors, trainee doctors, and nurses in Pediatric hospital, Adult Emergency, Family Medicine, Infectious Diseases, and Clinical Microbiology and Dermatology departments. Healthcare professionals who agreed to participate were interviewed face-to-face, including questions about independent variables such as gender, age, occupation, working unit, and history of disease. The dependent variable was the seropositivity/seronegativity status of the participants, which was determined according to the quantitative anti-Rubella IgG antibody levels measured by the ELISA method from serum samples. P< 0.05 was accepted as statistical significance. Results: During the study period, 326 out of 368 healthcare professionals in the units in question agreed to participate (88.5%). Of the participants, 79 (24.2%) were seronegative and 247 (75.8%) were seropositive. Seronegativity increased with decreasing age (p=0.036) when evaluated according to age groups. Seronegativity was 29.4% in the 20-29 age group, 19.2% in the 30-39 age group, and 10.7% in the 40-49 age group, while all participants aged 50 years and over were seropositive. Seropositivity was not affected by gender (p=0.260), occupation (p=0.364), or department (p=0.129). The study group's median anti-measles IgG antibody level was 654 IU/ml (65-5000 IU/ml). The median antibody level increased with increasing age (p<0.001). Conclusion: In our study, a significant proportion of healthcare professionals at risk for encountering measles were susceptible. [ABSTRACT FROM AUTHOR]

Introduction: In this study, we aimed to determine the relationship between bacteremia and procalcitonin (PCT) and the cut-off value of PCT in detecting bacteremia. Methods: Adult (>18 years old) patients admitted to our hospital's emergency department and diagnosed with sepsis between January 1, 2019, and April 1, 2022, were evaluated retrospectively. Patients whose complete blood count, C-reactive protein (CRP), PCT, and biochemical tests were performed and who had two sets of blood cultures taken before antibiotics were started were included in the study. Patients with and without bacteremia were compared in terms of PCT, CRP, leukocyte count, and age. The cut-off value was determined for PCT in detecting bacteremia. Results: Of the 4036 patients evaluated, 301 patients were included in the study. 174 (57.8%) of the patients were male and 127 (42.2%) were female. Bacteremia was detected in 19% (56) of the cases. The most common pathogen was coagulase-negative staphylococci (46%), and Escherichia coli (23%) was the second most common. A cut-off value of ≥3.29 for PCT has 80% specifity, while the negative predictive value was 89.5% (area under the ROC curve [AUC]= 0.718, 95% confidence interval [CI]=0.663-0.768). There was a low level of positive correlation between leukocyte values and PCT values of the patients (r=0.373, p<0.001). Similarly, there was a low level of positive correlation between CRP values and PCT values (r=0.490, p<0.001). Conclusion: According to the results of the study, PCT value was found to have a high negative predictive value and high specificity in detecting bacteremia. Therefore, we conclude that PCT value should be measured for early and rapid antibiotic initiation in patients who apply to the emergency outpatient clinic and are suspected of having sepsis. [ABSTRACT FROM AUTHOR]

Introduction: Vaccination is one of the preventive measures that should be taken against COVID-19. In this study, we aimed to evaluate the COVID-19 vaccination status and factors affecting vaccination of healthcare workers (HCWs) working in our hospital. Methods: This cross-sectional study was conducted by filling out a questionnaire form with face-to-face or snowball methods to HCWs in our hospital. The questionnaire is composed of 10 questions, including demographic information, occupation of the person, working in the pandemic unit, COVID-19 and Influenza vaccination information, contracting COVID-19, and hospitalization status. Full-dose vaccination was defined as four doses in total. P<0.05 was accepted as a statistical significance level. Results: We included 744 HCWs in this study. The median age was 32 (17-60) years, and 60.8% (n=452) were women, mostly nurses (32.3%, n=240). The vaccination rate after contracting COVID-19 was 56.9% (n=269). Vaccination rates against COVID-19 were higher in women (94.5%) than in men (93%), in those who were vaccinated against influenza (99.4%) than those who were not (91%), and in doctors (99.3%) than in nurses (92.5%) and other HCWs (%90.8) (p=0.051, p=0.00, p=0.004). The rate of full-dose vaccination was found to be statistically significantly higher in those who worked in the pandemic unit (39.4%) than in those who did not (27.9%), in those who had influenza vaccination (44.5%) than those who did not (32.2%), and also higher in doctors (61.8%) compared to nurses (31.7%) and other HCWs (27.2%) (p=0.002, p=0.04, p=0.000). The rate of having COVID-19 disease was higher in HCWs who were unvaccinated or vaccinated with a missing dose (63.2%) compared to HCWs who were vaccinated with a full dose (41%) (p=0.000). Conclusion: Full-dose vaccination reduces the rate of COVID-19 disease, and doctors are more inclined to have fulldose vaccination than nurses and other HCWs. [ABSTRACT FROM AUTHOR]

Copyright of Turkiye Klinikleri Journal of Sports Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Turkiye Klinikleri Journal of Sports Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Turkiye Klinikleri Journal of Nursing Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Nursing Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Nursing Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Nursing Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Nursing Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Nursing Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)