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21 results on '"Otto O"'

1. [Rapid point-of-care serology testing for sars-cov-2].

Author

Stackelberg O, Esmaeilzadeh M, Olsen B, and Lundkvist Å

Subjects
COVID-19, COVID-19 Testing, Epidemiologic Studies, Humans, SARS-CoV-2, Sensitivity and Specificity, Time, Betacoronavirus immunology, Clinical Laboratory Techniques standards, Coronavirus Infections diagnosis, Coronavirus Infections immunology, Pandemics, Pneumonia, Viral diagnosis, Pneumonia, Viral immunology, Point-of-Care Systems standards
Abstract

Increasing evidence indicates immunity against severe acute respiratory syndrome coronavirus 2 (sars-cov-2) after covid-19, but it remains unclear for how long the protection remains. Serology testing seems to have a higher sensitivity than molecular diagnostics from 8 days after onset of symtoms, and should be part of risk assessment and epidemiological studies of COVID-19. The performance of commercial serological point-of-care (POC) lateral flow tests are highly manufacturer-dependant. Low sensitivity increases the risk of false negative results and could result in unnecessary quarantine of test persons with developed antibodies. Low specificity increases the risk of false positive results and could lead to false assumptions of immunity. Carefully selected serological POC tests for sars-cov-2 can be used in large scale testing but should only be used by licensed medical staff able to understand their limitations and interpret the results.

Published
2020

2. [Serrated polyps is a hidden but common cause of colorectal cancer].

Author

Thorlacius H, Ljungberg O, and Toth E

Subjects
Adenoma complications, Adenoma diagnosis, Adenoma pathology, Adenoma surgery, Colonic Polyps diagnosis, Colonic Polyps pathology, Colonic Polyps surgery, Colonoscopy, Colorectal Neoplasms diagnosis, Colorectal Neoplasms pathology, Colorectal Neoplasms prevention & control, Humans, Hyperplasia complications, Hyperplasia diagnosis, Hyperplasia pathology, Hyperplasia surgery, Colonic Polyps complications, Colorectal Neoplasms etiology
Abstract

The concept that serrated polyps can cause colorectal cancer is relatively new and not very well-known. Serrated polyps are difficult to identify and treat endoscopically. This together with the fact that premalignant serrated polyps are mainly located in the proximal colon might help explain why colonoscopy is less effective against right-sided compared to left-sided colorectal cancers and why interval cancers usually appear in the proximal colon. In fact, serrated polyps may cause up to one third of all sporadic colorectal cancers. In spite of this, the aetiology, incidence, prevalence and natural history of serrated polyps remains elusive. Endoscopists and pathologists must have a good understanding of serrated polyps in order to effectively diagnose, treat and follow up these lesions. This review focuses on the pathophysiology, types, work-up, treatment and follow-up of serrated polyps in the colon and rectum.

Published
2015

4. [Fellowship success story in Lund].

Author

Nordenström E, Karlsson S, Ljungberg O, Persson E, Tennvall J, Eriksson M, Thorbjörn Karlsson, Mijovic Z, and Bergenfelz A

Subjects
Drug Industry economics, Humans, International Educational Exchange economics, Sweden, Fellowships and Scholarships economics
Published
2014

5. [National recommendations for the treatment of pharyngotonsillitis are valid].

Author

Cars O, Mölstad S, Norman C, Ternhag A, André M, and Erntell M

Subjects
Anti-Bacterial Agents therapeutic use, Humans, Sweden, Pharyngitis complications, Pharyngitis diagnosis, Pharyngitis drug therapy, Practice Guidelines as Topic, Streptococcal Infections complications, Streptococcal Infections diagnosis, Streptococcal Infections drug therapy, Tonsillitis complications, Tonsillitis diagnosis, Tonsillitis drug therapy
Published
2012

6. [Metronidazole cream approved for nonprescription use].

Author

Edlund C, Rastad JA, Cars O, and Erntell M

Subjects
Administration, Topical, Drug and Narcotic Control, Humans, Rosacea drug therapy, Sweden, Anti-Infective Agents administration & dosage, Metronidazole administration & dosage, Nonprescription Drugs administration & dosage
Published
2011

9. [Penicillin V and how three dosages became two and than three again. History behind treatment of otitis, sinusitis and pharyngo-tonsillitis].

Author

Giske CG, Eriksson M, Hermansson A, Kumlien J, Odenholt I, and Cars O

Subjects
Administration, Oral, Anti-Bacterial Agents blood, Anti-Bacterial Agents history, Anti-Bacterial Agents pharmacokinetics, Child, Drug Administration Schedule, Evidence-Based Medicine, History, 20th Century, Humans, Microbial Sensitivity Tests, Penicillin V blood, Penicillin V history, Penicillin V pharmacokinetics, Treatment Outcome, Anti-Bacterial Agents administration & dosage, Otitis drug therapy, Penicillin V administration & dosage, Pharyngitis drug therapy, Sinusitis drug therapy, Tonsillitis drug therapy
Published
2010

10. [Antibiotics or not--procalcitonin can guide therapeutic choices. At least at the emergency department for adults with lower respiratory tract infection].

Author

Ternhag A, Cars O, Norman C, and Struwe J

Subjects
Adult, C-Reactive Protein analysis, Calcitonin Gene-Related Peptide, Critical Care, Decision Making, Emergency Service, Hospital, Humans, Pneumonia, Bacterial microbiology, Respiratory Tract Infections microbiology, Sensitivity and Specificity, Sepsis drug therapy, Sepsis microbiology, Anti-Bacterial Agents administration & dosage, Biomarkers blood, Calcitonin blood, Pneumonia, Bacterial drug therapy, Protein Precursors blood, Respiratory Tract Infections drug therapy
Published
2010

11. [Doxycycline is no antitussive agent. Antibiotics in acute bronchitis both unnecessary and risky].

Author

Ortqvist A, Holmberg H, Norman C, and Cars O

Subjects
Acute Disease, Anti-Bacterial Agents administration & dosage, Anti-Bacterial Agents adverse effects, Cough drug therapy, Doxycycline administration & dosage, Doxycycline adverse effects, Drug Prescriptions statistics & numerical data, Drug Resistance, Bacterial, Humans, Practice Patterns, Physicians', Risk Factors, Bronchitis drug therapy
Published
2009

12. [Ranking in health care results in wrong conclusions].

Author

Ranstam J, Wagner P, Robertsson O, and Lidgren L

Subjects
Data Interpretation, Statistical, Hospitals standards, Humans, Quality Indicators, Health Care, Treatment Outcome, Outcome Assessment, Health Care methods, Outcome Assessment, Health Care statistics & numerical data, Quality Assurance, Health Care methods, Quality Assurance, Health Care statistics & numerical data
Published
2008

13. [Surprising etiology behind severe headache and fever].

Author

Kuu-Karkku V, Knutar O, Varis J, Päivärinta M, and Järveläinen H

Subjects
Adult, Anti-Inflammatory Agents administration & dosage, Diagnosis, Differential, Female, Fever diagnosis, Glucocorticoids administration & dosage, Headache diagnosis, Humans, Hyperthyroidism diagnosis, Prednisone administration & dosage, Thyroiditis, Subacute drug therapy, Fever etiology, Headache etiology, Thyroiditis, Subacute diagnosis
Published
2008

14. [Shorten time of treatment in lower urinary tract infection in women and don't use quinolones!].

Author

Cars O, Struwe J, Norman C, and Sandberg T

Subjects
Anti-Bacterial Agents adverse effects, Anti-Infective Agents, Urinary adverse effects, Drug Resistance, Bacterial, Female, Humans, Quinolones adverse effects, Time Factors, Urinary Tract Infections microbiology, Anti-Bacterial Agents administration & dosage, Anti-Infective Agents, Urinary administration & dosage, Escherichia coli Infections drug therapy, Urinary Tract Infections drug therapy
Published
2008

16. [Antibiotic resistant S aureus--increased mortality and more expensive health care].

Author

Melander E, Burman LG, and Cars O

Subjects
Anti-Bacterial Agents administration & dosage, Anti-Bacterial Agents economics, Bacteremia drug therapy, Bacteremia economics, Bacteremia mortality, Drug Costs, Europe epidemiology, Humans, Infection Control economics, Risk Factors, Staphylococcal Infections drug therapy, Staphylococcal Infections economics, Staphylococcal Infections mortality, Drug Resistance, Multiple, Bacterial immunology, Health Care Costs, Methicillin Resistance immunology, Staphylococcus aureus drug effects, Staphylococcus aureus immunology
Published
2007

17. [STRAMA sticks to the otitis consensus].

Author

Norman C, Cars O, Söderström A, Groth AB, and Hermansson A

Subjects
Acute Disease, Child, Child, Preschool, Consensus, Drug Resistance, Bacterial, Drug Utilization, Evidence-Based Medicine, Guideline Adherence, Humans, Mastoiditis drug therapy, Practice Guidelines as Topic, Anti-Bacterial Agents administration & dosage, Otitis Media drug therapy
Published
2007

18. [Quinolones--a cure which became a threat. Accelerating resistance development demands stricter indications].

Author

Lytsy B, Cars O, and Torell E

Subjects
Animals, Drug Utilization statistics & numerical data, Drug Utilization trends, Europe, Fluoroquinolones administration & dosage, Humans, Methicillin Resistance, Practice Guidelines as Topic, Vancomycin Resistance, Drug Resistance, Multiple, Bacterial, Fluoroquinolones adverse effects
Abstract

Fluoroquinolones are important antibiotics for treatment of serious infections. Increased usage has, in many countries, resulted in rapid development of resistance towards this class of antibiotics. Moreover, it has been shown that use of fluoroquinolones is associated with selection of multi-resistant bacteria, such as methicillin-resistant S. aureus and vancomycin-resistant enterococci. The risks related to overuse of fluoroquinolones among both humans and animals are reviewed and strict indications for use are suggested.

Published
2005

19. [Penicillin V should be administered three times daily].

Author

Odenholt I, Cars O, Ostlund A, and Erntell M

Subjects
Drug Administration Schedule, Humans, Practice Guidelines as Topic, Anti-Bacterial Agents administration & dosage, Penicillin V administration & dosage
Published
2004

20. [Adaptation of working hours to EU directives does not require more physicians!].

Author

Larsson D, Uberbacher O, and Johansson C

Subjects
European Union, Humans, Personnel Staffing and Scheduling statistics & numerical data, Sweden, Workload statistics & numerical data, Personnel Staffing and Scheduling legislation & jurisprudence, Physicians statistics & numerical data, Workload legislation & jurisprudence
Published
2004

21. [Alarming signals concerning the increasing antibiotic resistance].

Author

Cars O

Subjects
Anti-Bacterial Agents administration & dosage, Anti-Bacterial Agents adverse effects, Communicable Disease Control, Cross Infection microbiology, Cross Infection prevention & control, Drug Utilization, Humans, Hygiene, Infection Control, International Cooperation, Respiratory Tract Infections microbiology, Respiratory Tract Infections mortality, Respiratory Tract Infections prevention & control, Drug Resistance, Bacterial, Global Health
Published
2002

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