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[Rapid point-of-care serology testing for sars-cov-2].
- Source :
-
Lakartidningen [Lakartidningen] 2020 May 27; Vol. 117. Date of Electronic Publication: 2020 May 27. - Publication Year :
- 2020
-
Abstract
- Increasing evidence indicates immunity against severe acute respiratory syndrome coronavirus 2 (sars-cov-2) after covid-19, but it remains unclear for how long the protection remains. Serology testing seems to have a higher sensitivity than molecular diagnostics from 8 days after onset of symtoms, and should be part of risk assessment and epidemiological studies of COVID-19. The performance of commercial serological point-of-care (POC) lateral flow tests are highly manufacturer-dependant. Low sensitivity increases the risk of false negative results and could result in unnecessary quarantine of test persons with developed antibodies. Low specificity increases the risk of false positive results and could lead to false assumptions of immunity. Carefully selected serological POC tests for sars-cov-2 can be used in large scale testing but should only be used by licensed medical staff able to understand their limitations and interpret the results.
- Subjects :
- COVID-19
COVID-19 Testing
Epidemiologic Studies
Humans
SARS-CoV-2
Sensitivity and Specificity
Time
Betacoronavirus immunology
Clinical Laboratory Techniques standards
Coronavirus Infections diagnosis
Coronavirus Infections immunology
Pandemics
Pneumonia, Viral diagnosis
Pneumonia, Viral immunology
Point-of-Care Systems standards
Subjects
Details
- Language :
- Swedish
- ISSN :
- 1652-7518
- Volume :
- 117
- Database :
- MEDLINE
- Journal :
- Lakartidningen
- Publication Type :
- Academic Journal
- Accession number :
- 32463475