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Objective: To evaluate the clinical course of atopic dermatitis (AD) in adults during the COVID-19 pandemic and to evaluate their comorbidities and cardiovascular risk. Methods: A cross-sectional study was conducted in adults with AD. Severity and control of AD, quality of life, levels of psychological stress, depression and cardiovascular risk were measured. Results: Forty-two patients were included. A decrease in POEM score (11.83 vs 10.12; p=0.004) and PO-SCORAD (37.77 vs 32.49; p= 0.001) was observed in comparison to the scores at pandemic onset. The quality of life correlated with the severity of AD (p<0.0001) while the levels of stress and depression did not show association. Most patients had a low cardiovascular risk. Conclusions: The results suggest a decrease in the current severity of AD compared with severity before pandemic. Quality of life is associated with AD severity. [ABSTRACT FROM AUTHOR]

The proposed objective is to identify the level of spirituality in university teachers during the context of the pandemic. The correlational descriptive quantitative methodology was used with Mann Whitney's U, Spearman's rho and Kruskal Wallis's H tests in 85 university professors from the Faculties of Health and Humanities of a public entity. Applying the Spirituality scale, the information was analyzed using SPSS, version 24. The results show high levels of spirituality in 96% of teachers. There are statistically significant differences in the scores with respect to age and sex in the spiritual needs dimension, with men and the group between 30 and 39 years old having the highest average (p <0.05). The self-awareness dimension predominated at the highest level. Conclusions: spirituality, as a construction given from beliefs, practices and own experiences, represents a relevant element for the care of being; considering it essential to face difficulties, especially in apparently disruptive situations such as COVID-19. In the experience of the pandemic, teachers adopt spirituality as a part of their being that gives value to themselves, guides the search for harmony with nature and focuses on their goals. [ABSTRACT FROM AUTHOR]

BACKGROUND: SARS-CoV-2 infection can be associated with a hypercoagulable condition, which increases the prevalence of thromboembolic processes and the risk of deep vein thrombosis and pulmonary thromboembolism. CLINICAL CASE: An 82-year-old hypertensive woman admitted to the emergency department due to arthromyalgia, severe asthenia and cough, associated with minimal dyspnea on moderate efforts and an increase in the perimeter of the lower right limb of 3 days of evolution. Upon arrival at the emergency department, she presented tachycardia and tachypnea at rest. In the emergency department blood test showed a D-dimer elevation of 21,131 ng/mL. The chest X-ray showed patchy lung opacities, which was consistent with COVID-19. The CT angiography of the pulmonary arteries showed findings of bilateral pulmonary thromboembolism and COVID-19 pneumonia. A second PCR was positive for SARS-CoV-2. The patient was hospitalized for 8 days and showed improvement with the use of anticoagulant treatment, so it was decided to discharge her with home isolation. CONCLUSIONS: Recently, cases of thromboembolism are being described in patients with coronavirus infection, but pulmonary thromboembolism occurred when patient was admitted to the intensive care unit or in prolonged stays, unlike our patient who initially presented bilateral pulmonary thromboembolism, which is rare. Other cases of postpartum pulmonary embolism and after hospitalization associated with COVID-19 have been described. Therefore, in a patient with COVID-19, special attention must be paid to thromboembolic complications. [ABSTRACT FROM AUTHOR]

COVID-19 pandemic has changed the normal course of activities around the World. The measures implemented to slow down the spread of the disease and its impact on the health system have also suggested a change in population dynamics. In the educational aspect, the paradigm of the traditional education had to change completely to a remote environment, representing a challenge for students, teachers, and education institutions. In this work we report the students' response to the actions taken by the faculty of the Chemistry Sciences School of Universidad La Salle México to face online courses ensuring student accompaniment. After the term, a qualitative and quantitative study was performed to the school population using an electronic survey to address the response of students to the applied strategy. Data was analyzed using SPSS® software. 266 responses were obtained, which represents a response rate of 44%. 75.6% of the alumni reported having a good or excellent disposition regarding virtual sessions. Likewise, 48.9% reported adapting appropriately to the remote working modality. Also, 83.5% of students recognize the labor of the teachers by acknowledging that their effort and dedication was excellent or good. Students showed development of soft skills such as self-time and learning management; written, oral and technological communication. These results suggest the advantages perceived by students during the transition to virtual modality, mostly oriented to self-management of their learning and that could conform the basis for the development of new strategies that can be useful not only for a contingency situation, but also in the structuration and innovation of science programs. [ABSTRACT FROM AUTHOR]

Introduction: The Covid-19 pandemic has brought social changes, also affecting communication. The use of social networks has increased during the confinement and the way of informing us through them or instant messaging such as WhatsApp have led to the viralization of hoaxes. Methodology: Through a pioneering survey during the confinement, we have collected more than 1700 responses that have been analyzed with machine learning techniques to learn how the Spanish have been informed during the confinement and how they have interacted with the information they received about the Covid- 19. In addition, we have participated in meetings with the founding partners of Maldita, a pioneer verifier in Spain, who has carried out fundamental work in detecting fake news during the pandemic. Results: The results show different behaviors in the use of social networks, especially at different ages: why they share information; if they doubt her; what kind of hoaxes have they received; what types of contacts do they receive most often, etc. Conclusions: Different profiles of information consumers are appreciated, some more aware of the reliability of the networks, who also verify the dubious content and another that is reported in a more superficial way and that does not verify the information that comes through these online channels. [ABSTRACT FROM AUTHOR]

The coronavirus epidemic (Covid-19) unleashed worldwide has had repercussions in all social sectors, and the world of culture in general and of publishing in particular have not been an exception. The need to adopt confinement measures has determined the closure of all public spaces related to reading, such as libraries, bookstores and cultural centers, with serious consequences for the sector that has seen its activity to stop. Faced with this situation, there have been numerous actors involved, such as authors, publishers, bookstores, but also individuals, who have developed a set of initiatives to try to alleviate these effects, both for the editorial segment and for the population. On the one hand, the online acquisition systems, advance purchases, flexible deliveries, etc., have been strengthened. And on the other, from the publishing sector, authors, publishers and booksellers have proposed the release of titles for free online reading, or the development of personalized recommendation systems for readers, among many other initiatives. The consequence of all this has been an important growth in the consumption of digital content, verifiable above all in the increase in loans in systems such E-biblio in Spain, and similar platforms in other countries. These movements, although they are of a conjunctural nature, have revealed the possibility of other forms of consumption and distribution of content, little frequented by a large part of the population that, out of necessity, has tried other reading formulas that always look good as an alternative to traditional ones, either as a complement or as another mode of appropriation and consumption that may be the prevailing one in the future. [ABSTRACT FROM AUTHOR]

Introduction: During the COVID-19 health crisis, the information in the media has focused mainly on this topic and the interest of citizens has also increased in this regard. Objective: This work shows the profiles of the Spanish users regarding the consumption of information during confinement. Methodology: For this, an online survey was carried out that was pioneering at the time of its launch, which has allowed us to obtain a significant sample. The methodology established for data management has been carried out by counting unique users, machine learning techniques have been used, and the affinity analysis model has been used to discover co-occurrence relationships in the items. Results: In this way, we have been able to determine which means have been most reliable for citizens when it comes to learning about the coronavirus and whether there is a correlation in terms of the means they consume between them. Conclusions: Definitively, co-occurrence has been established between users who trust a certain medium and other means that are also trusted and they have a similar ideological trend. [ABSTRACT FROM AUTHOR]

Objectives: To standardize and validate an in-house RT-LAMP test for the detection of SARS-CoV-2, based on laboratory and field assays using samples from COVID-19 suspected patients. Materials and methods: An in-house SARS-CoV-2 RT-LAMP molecular test was standardized, establishing the detection limit with Vero cells of isolated Peruvian strains of SARS-CoV-2, and the robustness to various concentrations of primers. The laboratory validation was performed with 384 nasal and pharyngeal swab samples (UFH) obtained between March and July 2020. The field validation was performed with 383 UFH obtained from COVID-19 suspected symptomatic cases. All samples were tested by RT-LAMP and RT-qPCR. The RT-qPCR was considered as the reference standard test. The concordance measures and diagnostic performance were calculated. Results: The detection limit was consistent in cases with Ct <30 in both tests, showing efficiency to detect up to 1000 copies/μL of the target gene. Robustness was evidenced with half of the primer concentrations and 20 μL of final volume. Absence of amplification was identified for other HCoVs. Concordance showed a kappa index of 0.88 (95% CI: 0.83-0.93) and 0.89 (95% CI: 0.84 - 0.94) in laboratory and field settings, respectively. The sensitivity value in the laboratory was 87.4% (95% CI: 80.8 - 92.4) and 88.1% in the field (95% CI: 81.6 - 92.9). The specificity value in both settings was 98.8% (95% CI: 96.4-99.7). Conclusions: The in-house SARS-CoV-2 RT-LAMP test was successfully validated based on its adequate robustness, no cross-reactions, good concordance, and diagnostic performance compared to RT-qPCR. [ABSTRACT FROM AUTHOR]