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RESUMEN La especie Vibrio puede formar una simbiosis con animales marinos produciendo bioluminiscencia y en otros casos puede causar enfermedad en peces y humanos. La simbiosis y la patogénesis depende de la expresión de factores de virulencia regulados por el Quorum Sensing (QS). El objetivo del presente estudio fue describir los múltiples sistemas QS en Vibrio, controlados por moléculas autoinductoras como el autoinductor-1 (acil homoserina lactonas), el (S)-3-hidroxitridecan-4-ona (CAI-1), el autoinductor-2 (furanosil borato di-éster), el autoinductor-3, la noradrenalina y la epinefrina. Además, se describen los principales reguladores transcripcionales de QS como el regulador maestro AphA (a baja densidad celular), los reguladores transcripcionales LuxR, HapR, LitR, LsrR, QseB y KdpE (en alta densidad celular). También, se describen algunas moléculas que regulan el mecanismo de QS como el óxido nítrico (NO), la etanolamina, el 3,5-dimetil-pirazin-2-ol (DPO) y el ciclo-(L-Phe-L-Pro), activando la simbiosis, la patogenia, la defensa y la unión con fagos facilitando la lisogénesis de Vibrio. De igual modo se describieron los mecanismos de co-regulación de fenotipos por medio de los reguladores transcripcionales LuxR y AphA. Concluyendo que en la actualidad el sistema QS de Vibrio continúa en estudio, se han descubierto nuevas moléculas señal, nuevos mecanismos y proteínas que co-regulan la red de señalización de QS en Vibrio y varios fenotipos como la producción de autoinductores, la bioluminiscencia, la movilidad, la biopelícula, la morfología, la producción de polisacáridos, la simbiosis, la utilización de hierro y los sistemas de secreción (1, 3 y 6). ABSTRACT Vibrio species can form a symbiotic relationship with marine animals and produce luminescence, but they can also cause disease in fish and humans. The expression of virulence factors, which is controlled by Quorum Sensing (QS), is required for symbiosis and pathogenesis. This study aimed to describe the multiple QS systems in Vibrio that are controlled by autoinducer molecules such as autoinducer-1 (acyl homoserine lactones), (S)-3-hydroxytridecan-4-one (CAI-1), autoinducer-2 (furanosyl borate diester), autoinducer-3, norepinephrine, and epinephrine. Furthermore, the main transcriptional regulators of QS are described as the master regulator AphA (activated to low cell density), the transcriptional regulators LuxR, HapR, LitR, LsrR, QseB, and KdpE (activated to high cell density). Also, are described some molecules that participate in the regulation of the QS mechanism, such as nitric oxide (NO), ethanolamine, 3,5-dimethyl-pyrazin-2-ol and cyclo-(L-Phe-L-Pro), activating the symbiosis, pathogenesis, defense and phage binding to facilitate lysogenesis of Vibrio. At the same time, the co-regulation of phenotypes by means of transcriptional regulators LuxR and AphA. Concluding that at present the Vibrio QS system continues in study, new signal molecules, mechanisms and proteins have been discovered that co-regulate the QS signaling network in Vibrio and various phenotypes such as autoinducer production, bioluminescence, mobility, biofilm, morphology, polysaccharide production, symbiosis, iron utilization and secretion systems (1, 3 and 6)., {"references": ["Metzger LC, Matthey N, Stoudmann C, Collas EJ, Blokesch M. Ecological implications of gene regulation by TfoX and TfoY among diverse Vibrio species. 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RESUMEN El género Paraburkholderia comprende más de 100 especies, las cuales pueden ser aisladas de diversos ambientes como plantas, suelos agrícolas, suelos volcánicos e incluso, a partir de cuerpos de agua. Existen pocos estudios en nuestro país que reportan el aislamiento de miembros pertenecientes a este género. En éste trabajo, se estudió la posición taxonómica de siete cepas rizosféricas pertenecientes al grupo de Burkholderia sensu lato, aisladas en el municipio de Chignahuapan del estado de Puebla de árboles maderables como el pino y de plantas silvestres como los helechos y las bromelias, utilizando un enfoque taxonómico polifásico. Con base en las secuencias de los genes ARNr 16S, atpD y recA se confimó que todas las cepas pertenecen al género Paraburkholderia y que GB45, GB51, GB53, GB62, GB152 y GB203 forman un clúster con Paraburkholderia sediminicola y Paraburkholderia aspalathi, con excepción de la cepa GB190, la cual podría representar una nueva especie al separarse de este grupo como lo demuestran los árboles filogenéticos. Con respecto a la caracterización fenotípica, las siete cepas de Paraburkholderia mostraron un crecimiento óptimo a una temperatura de 35 °C y un pH 6 en ausencia de NaCl. La tolerancia a distintas concentraciones de metales pesados (Co, Pb, Mo, Ni, Zn y V) fue diversa, así como en las pruebas de antibióticos. La cepa GB51 fue la única que creció en presencia de zinc hasta 200 ppm y en vanadio hasta 50 ppm, mientras que la cepa GB190 no creció a 39 °C y a un pH 4 pero fue la única cepa que si lo hizo en presencia de gentamicina a una concentración de 1 µg/mL y kanamicina a 2.5 µg/mL, estas características fueron las que la diferenciaron del resto de los aislamientos. ABSTRACT The genus Paraburkholderia comprises more than 100 species, isolated from various environments such as plants, agricultural soils, volcanic soils, and even water bodies. Few studies in our country report the isolation of members belonging to this genus. In this work, we focus on the taxonomic position of seven rhizospheric strains belonging to the Burkholderia sensu lato group, all of them were isolated from timber trees such as pine and wild plants such as fern and bromeliads, in the municipality of Chignahuapan situated in the state of Puebla using an approach polyphasic taxonomic. Based on the sequences analysis of the 16S rRNA, atpD, and recA genes confirmed that all the strains belong to the genus Paraburkholderia, even GB45, GB51, GB53, GB62, GB152, and GB203 form a cluster with Paraburkholderia sediminicola and Paraburkholderia aspalathi, except for the GB190 strain, which might represent a new species of this genus because it is separated from this group, as shown by phylogenetic trees. Regarding the phenotypic characterization, the seven strains showed an optimal growth at at 35 °C and pH 6.0 in the absence of NaCl. The ability to tolerate different heavy metal concentrations (Co, Pb, Mo, Ni, Zn, and V) and antibiotics concentrations (ampicilin, gentamicin, tetracyclin, kanamycin, and chloramphenicol) was diverse. Only the GB51 strain grew in the presence of zinc (≤200 ppm) and vanadium (≤50 ppm). 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