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Los métodos para evaluar el riesgo en salud se basan, en general, en el monitoreo ambiental y en la estimación de la exposición a través de modelos matemáticos. La incertidumbre de tal estrategia es grande. En consecuencia, para incrementar la certidumbre sobre la evaluación de la exposición a los contaminantes, se ha propuesto el empleo de biomarcadores. No obstante, la complejidad de los nuevos escenarios de riesgo obliga a evaluar no solamente a las poblaciones humanas sino también al resto de la biota. Asimismo, factores ambientales, sociales y de salud, al afectar la vulnerabilidad, también deben ser considerados para la caracterización del riesgo. Estos factores de vulnerabilidad pueden evaluarse a través de indicadores. Al final, con los análisis ambientales, el uso de biomarcadores y el manejo de indicadores ambientales, sociales y de salud, puede evaluarse el riesgo de manera integrada (humanos y biota). En esta revisión se presentan las diversas estrategias empleadas por este grupo de trabajo para evaluar el riesgo en sitios contaminados, comunidades marginadas y en áreas afectadas por el cambio global climático. The most commonly used methods for risk assessment are based on environmental analysis and the use of mathematical models for the estimation of exposure. However, the uncertainty of this approach is high, as the models are based on scenarios that may be not the correct ones. In order to decrease the uncertainty, the use of biomarkers has been proposed. Furthermore, considering the complexity of pollution in some sites, these biomarkers can be used both in humans and biota in order to obtain better information for the definition of risks at those sites. In addition to biomarkers, social, health and environmental indicators have to be applied for risk characterization, as different factors of vulnerability can modify the extent of health risks in some communities. At the end, with environmental monitoring and the use of biomarkers and indicators of vulnerability, health risks in humans and biota (integrated risk assessment) can be assessed in different scenarios. In this paper we present the strategies that our group developed for the study of hazardous waste sites, vulnerable communities and areas impacted by climate change. Os métodos para avaliar o risco na saúde se baseiam, em geral, no monitoramento ambiental e na estimação da exposição através de modelos matemáticos. A incerteza de tal estratégia é grande. Em consequência, para incrementar a certeza sobre a avaliação da exposição aos contaminantes, tem sido proposta a utilização de biomarcadores. No entanto, a complexidade dos novos cenários de risco obriga a avaliar não somente as populações humanas mas também ao resto da biota. Da mesma forma, fatôres ambientais, sociais e de saúde, ao afetar a vulnerabilidade, também devem ser considerados para a caracterização do risco. Estes fatôres de vulnerabilidade podem avaliar-se através de indicadores. Finalmente, com as análises ambientais, o uso de biomarcadores e o manejo de indicadores ambientais, sociais e de saúde, pode-se avaliar o risco de maneira integrada (humanos e biota). Nesta revisão se apresentam as diversas estratégias empregadas por este grupo de trabalho para avaliar o risco em lugares contaminados, comunidades marginalizadas e em áreas afetadas pela mudança global climática.

Industrial countries face the consequences of decades of inappropiate handling of hazardous waste. The dumping of al1 types of hazardous materials has been ongoing in most industrialised countries for hundreds of years. Large quantities of industrial and other waste material have been buried in landfill sites. A relatively large number of these lack reliable man-made or natural geological barriers and toxic fluids are scaping and polluting the groundwater. The problem is greatly aggravated when a soil covenng is placed over the waste and there is no information about the dumping practices used in the past. One of the first tasks in any remedial action is to delineate the physical extent of the sites and its encroachment into the surrounding area. Test borings and limited excavations are very valuable but the information obtained is not continuous and dheir destructive nature makes it possible that waste could inadvertently be released during the probing phase. In this regard, both borehole drilling and excavation are very dangerous to workers and the environment and expensive and tedious to conduct.Many of these problems may be alleviated by using a geophysical assisted system approach to determine where the pollutants will go in the subsurface, gain more complete understanding of site conditions and asses the optimal placement of exploration drills and monitonng wells. At hazardous waste sites, the main objectives must commonly include:- Determine the presence, location, distribution, depth and composition of possible buried wastes.- Determine the presence and extent of contaminant and leachate plumes within the unsaturated and saturated zones.- Characterise and asses the local (and regional) geohydrologic regime for groundwater flow paterns, recharge areas and localised permeable pathways.