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In the mid 1920s, Virginia Woolf was engaged in a dispute with the American critic Logan Pearsall Smith on “the ethics of writing articles at high rates for fashion papers”. Harper’s Bazaar, a commercial magazine to which Woolf contributed four short stories between 1930 and 1939, was a feminine periodical that exploited modernism’s distinction and high cultural capital to captivate a sophisticated, but essentially middle-class, readership by selling the illusion of upward cultural mobility. Although Woolf referred to her high-quality contributions to Harper’s Bazaar as “pot boiling stories for America” written “to make money”, it seems clear that her own engagement with a middlebrow publishing venue did not in the least affect her reputation as a highbrow intellectual and was indeed typical of the multifaceted, reciprocal relationship between the magazine and high modernism in a context in which mobility also meant redrawing the boundaries between intellectual and popular culture. The publication of modernist content within the glossy pages of Harper’s Bazaar was advantageous to both modernists seeking to maintain their celebrity status and the periodical itself, which attempted to cultivate and sustain a refined audience. Much in line with her work of the 1930s, Woolf’s short stories engaged with social and ethical issues such as the righteousness of penetrating other people’s lives and innermost truths (“In the Looking Glass”), violence and decay (“The Shooting Party”), capitalism and antisemitism (“The Duchess and the Jeweler”), human and non-human worlds (“Lappin and Lapinova”). Though often considered as non-canonical in terms of both their rather prosaic plot as well as characterisation, and the commercial venue in which they appeared, the stories Woolf wrote for Harper’s Bazaar reflect the preoccupations of the last decade of her career and are indicative of the tensions between high and low in modernist culture.

New Ukrainian and world realities set new tasks for the higher educational establishments, which are related to the search for new, modern methods that allow to increase the effectiveness of training. Currently, topical are the issues of not only professional but also the personal development of the student forming the priority in the implementation of educational activities in universities, preparation for future professional activities, as well as for successful interaction in society. The concept of «individual social competence» is an important factor in creating a system of educational process which takes into account aspects of professional development, and at the same time the peculiarities of the formation of the student personality. The author analyses the concept of «competence», considers the key competences for lifelong learning, identified by the European Parliament and the Council of the European Union, including social competence, studies the scientific achievements of Ukrainian and foreign scientists, including G. Gedviliene, H. S. Han, K. M. Kemple, U.P. Kanning, M. Horenburg, G.W. Ladd, H. K. Ma, K. Monahan, M. Monnier, O.V. Varetska, N.I. Hlebova, D.V. Hubareva, O.I. Hura, M.O. Doktorovych, I.B. Zarubinska, O.O. Subina, V.M. Shakhrai. They explored different aspects of social competence of different age categories. The author concludes that, despite different interpretations, all scientists agree that social competence is an acquired skill, it can be formed and developed throughout life. It was also determined that the developed social competence determines the status of the individual in society, it affects the success in professional activities. The high level of social competence allows a person not only to be realized in professional activities, but also to influence the processes in society, which in turn determines its stability. The author’s definition of the concept of «individual social competence» is given in the paper; the author concludes that social competence is an integrated ability that contains other competencies: spiritual, civic, communicative, linguistic; the concept of social competence is closely related to professional competence, without the successful interaction of the individual with society it is impossible to acquire the skills and abilities inherent in a qualified specialist. Thus, an important task for modern higher education is the formation and development of social competence of students, which is the key to successful implementation of the future specialist in professional activities. The educational process should be aimed at forming a system of knowledge about interaction in society, understanding the system of social values, ability to cooperate in society, the ability to communicate constructively, because only a socially competent person can.

The article traces the changes in the aesthetic conventions of Modern art in accordance with the dynamics of literary development in Great Britain. The study focuses on three key areas: the impact of “the ancients and moderns” quarrel on European philosophical and literary thought; the nuances of critical and literary discourse in Enlightenment-era Great Britain; and the reception of the Enlightenment aesthetic values and novelties in Victorian criticism, linking them to the emergence of twentieth-century modernism. The subject involves the evolution of Enlightenment aesthetics and poetics in Great Britain, particularly the departure from classical art and literature models, and the emergence of concepts like imagination, novelty, and the reader’s subjective experience of art. Seminal literary-critical essays of the eighteenth century, including works by Joseph Addison, Henry Home, Richard Hurd, and Leslie Stephen’s monograph ‘History of English Thought in the Eighteenth Century”, are analyzed. The paper also examines philosophical texts by Michel de Montaigne, Francis Bacon, René Descartes, and Marquis de Condorcet to understand the oscillatory nature of philosophical thought before and during the Age of Enlightenment. The study contextualizes “the ancients and moderns” debate on models for literary excellence and accentuates its role in shaping the discourse of aesthetics and artistic creativity. Contributions by Enlightenment figures such as Addison, Home, and Hurd are explored, emphasizing how they reshaped the discourse of aesthetics by redefining the nature of beauty, the sublime, and the principles of artistic criticism, thereby influencing the literary and artistic productions of their time and beyond. Particular attention is paid to the critical views of Stephen who wrote about the “fluctuating mode” of the literature of the second half of the eighteenth century, illustrating his peculiar subjectivism as an exponent of the Victorian worldview (Stephen saw Sterne’s novels as a serious moral threat), and simultaneously reflecting the normative aesthetic views of the second half of the nineteenth century. The paper also demonstrates how the antinomianism in aesthetic thinking, which challenged traditional norms and values as seen in “the ancients and moderns” quarrel, was further evolved in the works of Friedrich Schiller and Friedrich Schlegel, the latter articulating the antinomy of “classic versus romantic”. This tradition of antinomian thinking, coupled with the rejection of the idea of linear progression in cultural evolution, a call for a reassessment of values amidst a paradigm shift in culture and the breakdown of traditional ethic and aesthetic systems, finds a notable and unique expression in Friedrich Nietzsche’s works, that significantly influenced the transition from Modernity to Postmodernity. In summary, it is argued that the Modern Age was the time of the emergence of a new aesthetic sensibility, and its aesthetic pluralism and anti-classical literary ideas were pivotal in redefining concepts of progress, novelty, and human consciousness in art and literature. This laid the groundwork for modernist art and literature, characterized by a departure from tradition and a quest for new artistic expressions of human experience.

The paper aims to clarify the biblical image-symbols in Frank Peretti’s mystical thrillers. The problem of the detailed analysis of the lingual representation of the biblical image-symbols and their pragmatic value is solved in the article by applying a complex of methods of linguistic poetics, cognitive linguistics, stylistics and methodological tools of discourse analysis. The paper considers the biblical images-symbols, used in American mystical thrillers written by the protestant author Frank Peretti, as biblical intertexts depicting not only biblical knowledge but also author’s intentions and beliefs in conveying the most profound ideas and principles of the literary texts. Executed in the written works by lexical means, biblical image-symbols become the heart of biblically-marked contexts, which are differentiated according to their addressee orientation into author`s and character`s biblically-marked contexts and their scope – into propositional, composite, and complex biblically-marked contexts. The lingual representation of the biblical image-symbols is differentiated according to their structure into one-component (anthroponyms, toponyms, artifact, animalistic, anthropomorphic) and multicomponent, (two-component, three-component and four-component). The type of semantic transposition in the meaning of the lingual representation and pragmatic value of the biblical image-symbols determined the distinguishing of metaphoric and metonymic linguistic classification of the biblical image-symbols. Metaphoric are classified according to their structure (onecomponent and multi-component), their stylistic characteristics (language and speech metaphoric linguistic representants of the biblical image-symbols), and their denotative meaning (anthropomorphic, naturalmorphic, zoomorphic, and phytomorphic). Metonymic are differentiated according to the kinds of the metonymic transference of meaning into four groups: metonymy of belonging, metonymy of place, metonymy of signs, and metonymy of phenomenon.

In the paper, on the basis of a multimodal critical discourse analysis of political posters and social media posts, the authors outline the complex interplay of multimodal means serving to convey a political leader’s charisma. The paper aims to advance a set of historically conventionalized features typical of the charismatic personality (such as intelligence, self-confidence, persistence, ability to inspire, sociability, dominance, narcissism, and vision), present the updated definition of this notion, and substantiate theoretical and methodological grounds for the study of the interplay of multimodal means portraying a charismatic political leader that assist in conveying a political speaker’s charisma creation through its graphical image, namely political posters and social media posts. The results of the study reveal that charisma is a complex communicative and cognitive phenomenon reflecting person’s beliefs about certain innate, obtained or promoted by media, internal or external subliminal traits of a leader. These beliefs are shaped in the recipients’ consciousness during interactive communication on the basis of the leader’s strategy, techniques, and methods used in oral or written communication, as well as a set of linguistic and extralinguistic means associated with the speaker’s ability to satisfy certain needs of the community. As a study material the authors opted for the images of Boris Johnson, a politician already acknowledged as a charismatic one by international audiences, who has been a prominent political figure for almost a decade and has recently come to the forefront of political and diplomatic support of Ukraine in the ongoing Russian-Ukrainian war. The carried out analysis proves the highly informative as well as subliminal potential of multimodal visual pictographic means aimed at creating a charismatic image of a public person. The authors outline a set of verbal (elliptical sentences, catchy slogans in imperative mood, assonance, alliteration, the use of first person plural pronoun “We”, the lexical unit together, etc.) and visual-graphical means (font of the message, symbolic colour scheme, clothes style, body posture, gestures, oculesic features, etc.), whose interaction is aimed at triggering cognitive processes in the recipient’s mind in perceiving a charismatic image of the politician. Boris Johnson’s charisma is confirmed by the survey conducted among British and Ukrainian respondents as well as by his subscribers’ reactions, comments and likes following his posts on social media. The carried out analysis allows summarising the markers of a politician’s charisma portrayed on social media as follows: the number of comments and likes for their posts; informality while addressing the Prime Minister by his first name “Boris” and presence of a “popular name” “BoJo”; high degree of the followers’ messages expressiveness actualised through verbal means (significant amount of exclamatory sentences, interjections, evaluative epithets and idiomatic expressions), as well as graphical-visual means, in particular through the usage of graphic emoticons (emojis), serving to intensify the overall expressiveness of a message. The conclusion is that social media graphical images are aimed at conveying charismatic political leaders’ vision, offering their followers support and promise of a better future, portraying them as approachable, down-to-earth, considerate but at the same time serious leaders, ready to work to endure a better future. The results of the performed study can provide grounds for interdisciplinary research of both oral and written charismatic communication within the cognitive approach framework considering verbal, nonverbal and paralingual means’ (physiological, psychological, social, etc.) interplay that allows the audience to perceive a speaker as a charismatic one.

The article represents an attempt to build and apply a linguosemiotic model of existential conflict research in modern English fictional discourse. The modern tendency of philological and socio-humanistic studies to involve the tools of semiotics, discourse theory, and multimodality in the process of complex analysis of a literary work as an artistic model of reality is highlighted. The research is based on practical blocks of illustrative material, selected discursive fragments from a literary work, which contain an existential conflict. Basically, the key point here is the analysis of intra- and interpersonal conflict based on the theoretical achievements of semiotics and linguosemiotics (Ch. Pierce, Yu. Lotman, U. Eco, G. Pocheptsov) and the theory of discourse and multimodality (G. Kress, K. O’Halloran, C . Forceville, M. Halliday). It makes it possible to provide a detailed research of existential conflict in fictional discourse with the identification of latent, ambivalent meanings and the relevant reconstruction and interpretation of the conflict by the reader. The paper aims at projecting the modern tendency towards the synergy of various aspects of conflict studies across the humanities. Therefore, the goal of the paper is to outline the advantages of an integral approach to the study of conflict in modern linguistic conflictology and to build a linguosemiotic model for the analysis and interpretation of existential conflict in fictional discourse. Thus, the paper`s core objectives involve: 1) to study the achievements of the semiotic and multimodal approach in its application to synthetic level communicative systems containing conflict; 2) to reveal the place, role and potential of the existential conflict in fictional discourse using the above-mentioned methods; 3) to present a linguosemiotic model for the study of existential conflict in modern English fictional discourse. The theoretical and methodological base of the research involves general-scientific methods of analysis, synthesis, deduction as well as the method of linguosemiotic and multimodal analysis to determine the components of semiosis of existential intrapersonal conflict in fictional discourse. The results of the research consist in the creation of an integral semiotic model of the analysis of existential conflict in modern English-language fictional discourse, which assumes the presence of a static and dynamic component in its structure, revealed, in particular, in the process of semiotic reading of the work in three successive stages of mimesis, semiosis, and synthesis. The process of conflict interpretation presupposes a comprehensive approach to semiotic reading activity developed in consecutive steps. The linguosemiotic means of representing the existential conflict at different levels of the literary work, which have a multimodal nature, have been revealed. The temporal, psychological, and sign-symbolic characteristics of the existential conflict, which make up the semiotic space or semiosphere of the literary work, are analyzed and classified. As a result of the identification and unification of the factors that determine the way of development of existential conflict in fictional discourse, the linguosemiotic model of the analysis of this type of intrapersonal conflict was reconstructed. The model covers the study of the semiotic components of the sign-symbolic, psychological and temporal space and the surface and deep levels of the semiotic reading of the literary work, at which the cognitive, behavioral and emotional aspects of the conflict are decoded and reconstructed.

Introduction The rising prevalence of electronic cigarette (e-cigarette) use has prompted concerns regarding its potential health implications. While much attention has focused on respiratory and cardiovascular effects, injuries, oral trauma, and bone fractures linked to e-cigarette use have received less scrutiny. This paper aims to comprehensively review the landscape of injuries, oral trauma, and bone fractures induced by e-cigarettes, shedding light on this underexplored facet of e-cigarette-related harm. Material and Methods This literature review has analyzed 16 papers. Inclusion criteria: researches and case reports published after 2015. PubMed and Google Scholar has been searched to identify the papers. Analysis of the Literature Existing literature suggests a growing incidence of injuries, oral trauma, and bone fractures associated with e-cigarette use, albeit with limited systematic investigation. Mechanisms underlying these injuries range from device malfunctions to inadvertent impacts during use. Case reports highlight a spectrum of injuries, including oral burns, dental trauma, and skeletal fractures, often involving the face and mouth regions. Conclusions Despite the lack of comprehensive epidemiological data emerging evidence underscores the need for heightened awareness and preventive measures to mitigate e-cigarette-related injuries. Enhanced education, regulation of e-cigarette devices, and promotion of safer usage practices are crucial steps towards reducing the burden of e-cigarette-related harm on oral and skeletal health.

Introduction and purpose Non-specific and specific lower back pain syndrome is one of the leading causes of musculoskeletal disability and affects more than half of the population worldwide. The aim of this paper is to confront the problem of lumbar pain, possible diagnostic options, conservative and surgical opportunities with long term satisfactory rate. State of knowledge The paper reviews literature on lower back pain syndrome, sciatica, radiculopathy and lumbar disc herniation in regards to detection of the problem, classifying it and possible methods of resolvement. The WHO defines lower back pain as one of the leading causes of musculoskeletal dysfunction and it focuses on reducing the occurrence by programs like WHO Rehabilitation 2030 Initiative, UN Decade of Healthy Ageing and others. The paper also focuses on non surgical options of treatment. Material and method A review of the literature available in the “PubMed” and Google Schoolar was conducted. We focused on differential diagnosis depending on clinical presentation and possible treatment methods depending on symptoms, pathogenesis of the disorder and available procedures. Summary Our review managed to present the current state of development, possible differential diagnosis, prevalence of neural compressions, sciatica and radiculopathy in different diagnostic options. By receiving multiple studies we confront varied opinions of specialists regarding the approach to lower back pain syndrome and favorable forms of care. Additionally we came to the conclusion that the difference of patients' long term satisfactory rate in regards to nonoperative and operative treatment is not significant, and flattens over the years.

Gilbert’s syndrome is the most common inherited jaundice worldwide. It affects 5-10% of the population. It is caused by a mutation of the UGT1A1 gene, which results in impaired bilirubin metabolism. It is a benign disease and does not affect the life expectancy of patients. Patients with Gilbert’s syndrome should be alert to factors that exacerbate the course of the disease, interactions with medications taken and possible comorbidities such as hemolytic anemia, cholelithiasis or schizophrenia. However, it is the responsibility of physicians with such patients under their care to properly educate patients. Gilbert’s syndrome carries not only the consequences associated with the mutation, but also has many benefits that patients may not be fully aware of. Mildly elevated bilirubin levels have an antioxidant and anti-inflammatory effect, which prevents the development of lifestyle diseases and cancer. Ongoing clinical trials suggest that this could be a great step toward new treatments for diseases affecting the entire human population. PURPOSE OF THE WORK: This review paper aims to show Gilbert’s syndrome as a multifaceted disease and to sensitize doctors' attention to patients with the described mutation. MATERIALS AND METHODS: An analysis of papers available in PubMed and Google Scholar was performed using the following key words: Gilbert’s syndrome, bilirubin, UDP-glucuronosyltransferase, Gilbert’s syndrome harmful and protective aspects, iatrogenic Gilbert’s syndrome RESULTS: The result of the work is to present Gilbert’s syndrome as a disease that carries medical problems directly related to the mutation, but also, in some cases, has a protective effect on affected individuals. The work highlights the complexity of the problem.

Introduction and purpose: Diabetes has emerged as a global lifestyle disease, with an alarming rise in cases, particularly of type 2 diabetes. In Poland, over 3 million people are diagnosed, and an estimated 4 million cases are expected by 2030. Effective treatment involves a multifaceted approach, including dietary intervention, physical activity, and pharmacological options. Incretins, such as glucagon-like peptide-1 (GLP-1), play a pivotal role in carbohydrate metabolism regulation, and GLP-1 analogs have become essential in managing type 2 diabetes. This paper explores the development and mechanisms of GLP-1 analogs, detailing their impact on insulin secretion, gastric emptying, and weight reduction. Description of the state knowledge: Various GLP-1 receptor agonists, including exenatide, liraglutide, dulaglutide, semaglutide, and the novel tirzepatide, are discussed. These drugs exhibit diverse pharmacokinetics, modes of administration, and effects on glucose metabolism and weight. Despite their efficacy, there is a concerning trend of off-label use, particularly for obesity treatment, leading to shortages for patients with valid prescriptions. This misuse is fueled by para-advertising on social media platforms, contributing to a surge in prescriptions and reimbursement costs. To address this, guidelines for GLP-1 analog use in obesity treatment are proposed, emphasizing the need for a stable drug supply and normalizing drug availability. Summary: In 2023, concerns intensified with reports of counterfeit GLP-1 analogs, prompting regulatory interventions. The paper concludes by underscoring the critical role GLP-1 analogs play in diabetes and obesity treatment, while emphasizing the importance of responsible prescription practices, guidelines adherence, and regulatory vigilance to ensure patient safety and mitigate the risks associated with misuse and counterfeit drugs.

Effective body posture entails the correct alignment of body parts in relation to each other and is crucial for preserving balance, stability, and the efficient operation of muscles and joints. The major types of posture abnormalities such as lordosis, kyphosis and scoliosis can lead to alterations in various areas of the body, such as stomatognatic system. The potential correlation between malocclusion and body posture remains a subject of controversy. The aim of this review is to investigate and evaluate the association between posture defects and malocclusion on the basis of literature. This literature review has analyzed 18 studies. Inclusion criteria: clinical researches published after 2010, regarding children and adults. PubMed and Google Scholar has been searched to identify the papers. In 18 analyzed studies, 2133 patients were enrolled (including 979 children aged 4-18). A positive correlation between scoliosis and different types of malocclusion has been proven by six papers. There are also other noteworthy dependencies, such as overjet and pelvic torsion, kyphosis and sagittal position of mandible, skeletal Class III and torticollis, cross bite and scapula plane. Adolescent Idiopathic Scoliosis significantly affects the stomatognathic system, leading to issues like crossbite, crowding, increased overjet, overbite, partial open bite, and midline deviation. Orthopedists should collaborate with orthodontists for comprehensive treatment, particularly during developmental stages.

This scientific paper focuses on the treatment of breast cancer, one of the most common cancers among women. Despite increased awareness and the popularity of screening tests, statistics indicate a significant rise in incidence. The paper presents breast-conserving treatment methods, including brachytherapy, as a modern technique with promising outcomes. It describes the physical properties of ionizing radiation used in brachytherapy, discussing the photoelectric effect, Compton effect, and the phenomenon of pair production. The paper then delves into the biological effects of ionizing radiation, emphasizing the dependence on the cell cycle phase. It highlights lethal, sublethal, and potentially lethal cellular damage, categorizing the effects of radiation interaction into early and late responses. The discussion transitions to the application of brachytherapy in breast cancer treatment, focusing on various techniques such as LDR, PDR, and HDR. The paper provides a detailed description of brachytherapy's use in breast-conserving treatment, considering contraindications, treatment planning, and Accelerated Partial Breast Irradiation (APBI) techniques. The radioisotopes used in brachytherapy are also presented, with special attention to Iridium-192. The physical and practical aspects related to this isotope are discussed, along with other commonly used radioisotopes such as Cesium-137, Cobalt-60, and Strontium-90. The paper concludes with a summary, emphasizing the significance of brachytherapy in breast cancer treatment and outlining its prospects for development. The authors highlight precision and shortened therapy duration.

Introduction and purpose: In our work, we focused on presenting the role of collagen supplementation and its impact on skin and joint health. We considered studies discussing the differences in the effects of collagen from various plant and animal sources. We also examined the influence of the degree of hydrolysis on the absorbability of the supplement. The aim of the paper is to comprehensively summarize knowledge on collagen supplementation, differentiating between its sources and forms. Material and methods: In our paper, we endeavored to address the subject of oral collagen supplementation comprehensively. We explored studies about various forms and sources of collagen. We also delved into the collagen supplementation impact on skin and joints health and impact of additives in enhancing the positive effect of collagen . State of knowledge: Oral collagen supplementation can be beneficial for skin and joints health. It promote collagen synthesis in human body increasing strength of skin and joints. The higher the degree of collagen hydrolysis, the more easily it is absorbed by the body. Additives in the form of vitamin C and A can enhance collagen synthesis. Results and conclusions: This review article indicates a growing interest in oral collagen supplementation and its impact on health. Although there are encouraging findings regarding positive effects, further research is necessary to better understand and determine the optimal conditions for achieving maximum supplementation benefits. This information may be crucial for clinical decisions made by physicians regarding joint reinforcement and anti-aging effects on the skin.

Introduction and purpose The term "probiotic" rooted in Latin, signifies 'for life,' reflecting the historical use of fermented products for therapeutic purposes. While browsing many websites devoted to healthy eating or popular science topics, we often came across the topic of probiotic food without any confirmation by scientific research. The aim of this paper is to confirm or exclude the presence of probiotics in popular foods. State of knowledge The paper reviews literature on the health benefits of various food that is traditionally considered probiotic, focusing on how they impact on varied health conditions. Defined by the WHO as living microorganisms conferring health benefits when consumed adequately, probiotics, mainly bacteria from Lactobacillus and Bifidobacterium genera, play a vital role in maintaining gut microbiota balance, regulating digestion, supporting the immune system and influencing mental and cardiovascular health. In addition, the paper also searches for scientific basis for their action. Material and methods A review of the literature available in the “PubMed” and Google Schoolar was conducted. We focused on checking whether the microorganisms contained in pickled food meet the WHO criteria for probiotics. Summary Our review managed to prove the probiotic effect of almost all presented food, except for miso. By reviewing many articles, we shed a lot of uncertainty on the repeated myth about the lack of probiotic effect of cucumbers preserved in vinegar and what is more, we found scientific assumptions about the probiotic effect of vinegar itself. Fermented food contains numerous strains of bacteria that are resistant to acid, bile and temperature in the human digestive tract and can be effectively used as a source of probiotics. Additionally, compared to probiotics from the pharmacy, fermented products provide not only probiotics, but also nutritional value, valuable fiber and vitamins, benefiting to our health.

Introduction and purpose: The purpose of this scientific paper is to review the current knowledge of the effects of red wine on human health, particularly with regard to cardiovascular disease. State of Knowledge: Since the 1990s, red wine has gained its status as a health-promoting alcohol through the French Paradox - when drunk in moderate amounts, it protects against cardiovascular disease. The authors have collected scientific papers on the health effects of alcohol, red wine and resveratrol-a polyphenol that is the main component with health-promoting effects of wine. On their basis, they analyzed the assumptions of the positive effects of wine reaching inconclusive conclusions. Summary: Despite the fact that both ethanol and resveratrol have a positive effect in in vitro studies, in population studies their effect is much less significant, either because the negative behavioral-health effects in the case of ethanol are omitted or the actual effective doses of resveratrol are omitted.

Context: Angular gyrus is an anatomical structure of the brain located in the parietal lobe, taking part in writing and reading, language-use, memory and attention and spatial recognition. It is supplied by the angular gyrus artery, which is one of the caudal branches of the middle cerebral artery. One of the clinical pathologies of the angular gyrus artery is the ischemic stroke of the angular gyrus in the dominant hemisphere, responsible for the presence of Gerstmann Syndrome: left-right disorientation, agraphia, alexia, acalculia and finger agnosia. This systematic review aims to present the variety of anomalies of the main cerebral artery and the angular gyrus artery. Objective: Preparing a systematic review of papers describing the course anomalies of the angular gyrus artery. Materials and methods: PubMed and Google Scholar electronic databases was searched for phrases: ‘Angular gyrus artery’, ‘Artery of angular gyrus’, ‘Middle cerebral artery branches’, ‘Branches of middle cerebral artery’, ‘Gerstmann Syndrome’ published between years 2015 and 2023. Also 3 papers published before 2000 were used. From the selected 30 papers, 6 were used to prepare this analysis. Results: The middle cerebral artery, from which arises the angular gyrus artery, is marked by a significant variety of its division, mainly the number of the dividing trunks of the artery. Depending on the type of the division, the angular gyrus artery can arise from the upper, middle or lower trunk and vary in sizes. It can also appear as a singular or two separate branches. Instances of the anomaly of both the angular gyrus artery and posterior parietal artery are rare, but reported. Conclusions: The angular gyrus artery is characterised by a number of anomalies in its course, separation from the middle cerebral artery, diameter and branching.

Introduction and purpose: Apples are a widely consumed fruit globally and are known to be a great source of nutrition. Studies have shown that apples contain high levels of antioxidants, dietary fiber, and vitamins that contribute to numerous health benefits. This paper aims to provide a comprehensive review of the impact of apples on human health. State of knowledge: The paper reviews the current literature on the health benefits of apples, focusing on their impact on various health conditions such as cancer, cardiovascular diseases, diabetes, and obesity. Additionally, it examines the role of apples in improving intestinal, immune, and cognitive function. The paper also discusses the potential mechanisms by which apples exert their health benefits, such as high levels of flavonoids, polyphenols, and dietary fiber. Summary: In conclusion, the vast body of evidence reviewed in this paper supports the notion that consuming apples regularly can contribute to better health outcomes. They may help reduce the risk of chronic diseases, such as cancer, cardiovascular diseases, and diabetes, as well as promote healthy gut microbiota and immune function. Despite the controversy surrounding the use of pesticides in apple cultivation, the benefits of consuming apples outweigh the risks. Therefore, it is highly recommended to include apples as part of a balanced and nutritious diet to promote optimal health and wellbeing. As the saying goes, "An apple a day keeps the doctor away".

Introduction and aim Diabetic foot ulcer (DFU) is a chronic condition that affects an increasing number of people each year[1]. Healing the ulceration requires cooperation between patients, specialists and scientists in order to achieve satisfactory results. Treating this type of wound is not only a therapeutic challenge[1,2,3,4,5,6], but also an economic one, which is why so much scientific research has already been made on this phenomenon[2,3]. Still scientists continue their quest for new cost-effective alternatives to current therapeutic options that would be consistent with contemporary knowledge and available engineering capabilities in pursuance of creating techniques and new dressings that will accelerate the healing of DFUs[2,3,7,8]. Factors such as stress, obesity, certain medications, and chronic diseases appear to negatively affect the process of repair [1,9,10,4,6,11]. Studies prove that aloe vera gel due to its healing properties, can be considered as a potential dressing that will expedite the mending process of diabetic foot ulceration[12,13,14]. In this paper, we performed a literature review of the applicability of aloe vera in the healing process of DFUs. Materials and methods Searching the available literature, including randomized clinical trials and systematic reviews, we drew on databases focusing on the effects of treatment for diabetic foot ulceration using Aloe vera. Conclusion: The current scientific research on the use of Aloe vera gel in diabetic foot ulcer treatment indicates that this method is safe, effective and inexpensive[2,3]. However the difficulty of treatment and the increasing prevalence of this type of wound pose a challenge to finding new solutions and exploring mechanisms in which aloe vera can have a possible role in the wound healing process. Nevertheless, this paper presents a promising impact of Aloe vera gel applicability in the healing process of diabetic foot ulcer.

Introduction and purpose: Currently, as the frequency of obesity is alarming, the role of many factors that could contribute in preventing and treating this condition are being researched, among them the certain food with beneficial health profiles - one of them is soybeans, specifically the isoflavones it contains. Populations that consume soy are known for lower risk of various disorders - among them obesity. The aim of this paper is to summarize the existing paper about the role of these bioactive components in the treatment of this condition. The search was conducted using PubMed and Google Scholarship databases. Brief description of the state of knowledge: Obesity is one of the leading challenges in today’s healthcare as it leads to various chronic diseases that are fraught in consequences. Current knowledge is pointing into the association between composition of the soy isoflavones and the lower risk of obesity. Results of the studies indicate that patients affected with obesity could benefit from introducing soy isoflavones into their diet along with other necessary modifications. Conclusions: Soy isoflavones are potential agents in the holistic obesity treatment. Consumption of isoflavones merits further recognition as foregoing results of conducted studies are pointing to its possibly meaningful role. It is worth mentioning that consumption of soy isoflavones is not only an anti-obese factor, but also presents various other health benefits and when consumed rationally poses no risk to human’s well being. We conclude that further studies would enable us to fully reveal the potential of those polyphenols.

The present paper functions as an introduction to this special issue of mediAzioni, which brings together selected papers presented at the Translating Europe Workshop entitled "L'intelligenza artificiale per la traduzione verso una nuova progettazione didattica?" (3 December 2021), focusing on the pedagogical implications of Artificial Intelligence (AI), with a particular emphasis on Neural Machine Translation (NMT). The article revolves around three main themes. First, it considers the impact of emerging neural technologies on language services, redefining the traditional role of the translator and creating new responsibilities and tasks. Despite the considerable progress that NMT has made compared to previous models, it still has shortcomings that are almost "invisible" because they often lack clear grammatical or morphosyntactic marking. Such errors require a certain cognitive effort to identify, since they involve problems that are less obvious to the untrained eye, such as textuality or inadequacies at the level of discourse. Secondly, the article looks more closely at professional practices, especially those related to pre-editing, post-editing and proofreading. Particular emphasis is placed on the indispensable role of the human in translation workflows that integrate NMT not only at the level of post-editing and text revision, but also at the level of translation project management. Finally, the paper moves on to the implications of NMT for the training of translators and beyond, discussing key insights from the workshop participants regarding future teaching practices at university level. The article concludes by outlining the structure of this special issue and providing a brief synopsis of the collected papers.

Ad hoc corpora are considered effective to deliver native-like technical (and legal) translation. This paper explores how the translation of a system-specific document such as an Italian procura alle liti (power of attorney to appear in court) can be addressed. Translating this legal document may be problematic due to the fact that it is not recurrent in the common law system, which contemplates other types of special powers of attorney (PoAs). This paper explores whether and to what extent a corpus-based translation is possible when L2 parallel texts are difficult to find in native contexts. To this aim, a translation project with technical translators and lawyers is carried out. The participants compose an ad hoc corpus which they consult as a language reference tool. The paper findings report that the translators' corpus-based translation is mostly a word-by-word rendering of the source text, which may sound unnatural to an expert of the field. The lawyers' translation partly deviates from source words, but addresses the communicative function of the source text. The paper highlights the need for a balance between the two strategies, for example by focusing on textual functionality and/or paraphrasing, although at the cost of a reduced formulaicity.

Forensic Linguistics as a discipline has gone through more than 30 years of development in China, which can be divided into the brewing period, the establishment and development period, and the comprehensive improvement period. Scholars have presented the origin and development of forensic linguistics in the form of papers, monographs, translations, textbooks, seminars, conferences and other forms, which promotes the future development of forensic linguistics. In the past decade, the study of forensic linguistics has mainly focused on the theoretical research of forensic linguistics, the application of legislative and judicial language, the translation and teaching of legal language. This paper will adopt the method of literature research to summarize the origin and development of Chinese forensic linguistics in the past 30 years, and to anticipate the future development direction of forensic linguistics in the light of the current research characteristics and the hotspot of the times, so as to provide references for the theoretical development and application practice of current forensic linguistics, and to better guide future discipline development in China.

This study considers TED talks as an effective authentic resource for mastering English. The purpose of the article is to outline a methodology for using TED talks in teaching English for specific purposes (ESP) at the university level. To achieve this goal, we set the following objectives: to introduce and describe the steps of utilizing TED talks, as well as provide examples to each step. We applied a number of methods which helped to fulfil the task of the paper. They include establishing the cognitive and educational value of ESP and its place in the system of university education; defining the tasks and its content of the discipline; developing methodical means and organizational forms of training according to these tasks and content. TED talks are informative presentations delivered by experts in their fields. They provide a great opportunity for language teachers to incorporate authentic listening and speaking tasks in their teaching methods. A welldesigned lesson plan that utilizes TED talks as a teaching tool can benefit ESP students in various ways. The methodology of incorporating TED talks in the teaching process should involve a series of steps that aim to maximize effective learning outcomes. These steps include selecting the theme of the talk, searching the TED talk, delivering the speech, designing pre-listening and post-listening activities. The article presents examples of exercises that can be done at each step with reference to specific TED talks from the site https:// ed.ted.com. The first step ensures that the chosen TED talks are suitable and engaging. Teachers can provide students with choices and allow them to vote. The aim of the second step is to support students’ understanding of the TED talk. The third step develops listening comprehension skills. The fourth step engages and promotes students’ active listening skills. The fifth step helps to develop skills of discourse analysis. The video content that the teacher chooses for the lesson should correspond to the professional interests of students. In such a way this video will be able to increase the motivation to study not only a foreign language but also specialized disciplines. The work with TED talks, however, differs from ordinary academic lectures and presentations. Thus, it requires special training of both the teacher and students. Firstly, students` level of English is an important factor defining the choice of a lecture. The teacher considers the level of listening skills, knowledge of the topic, and terminology. Secondly, it is important to take into account the duration of the presentation. If students are not familiar with the topic, they can have some difficulties with comprehension. Therefore, they will need to listen to the lecture twice. So, the preferable length of the video should be about 5-6 minutes. Incorporating TED talks as a teaching tool in English for Specific Purposes can be a highly effective way of promoting active learning in the classroom. TED talks are a source of authentic and relevant topics for students to engage in while providing a more enjoyable and efficient way of learning. The methodology of using videos from the resource has clear benefits. They include improving comprehension skills, vocabulary acquisition, note-taking, and speaking skills. By following the steps mentioned in this paper, lecturers can deliver enriching, pedagogical sessions that will provide students with a foundation to become successful professionals in their respective fields.

The issue of the relationships between anxiety and aggressiveness among Ukrainian women in war conditions has been dealt with in this article. The relevance of the chosen topic is beyond doubt, since social problems based on psychological factors are especially relevant during the war. It is substantiated that a change in the usual living conditions leads to a significant increase in anxiety and aggressiveness among women. In this paper, the attention is paid specifically to the study of anxiety and manifestation of aggressiveness by women who are in war conditions. It is worth noting that currently in the psychological and social literature, the number of publications about the problem of anxiety is increasing, since anxiety occupies a special place, as it often leads to a decrease in work capacity, productivity, difficulties in communication, etc. It has been found out that the level of anxiety can be manifested in the aggressive women’s behaviour in the war conditions. It is noted that the state of anxiety and aggressiveness is the most common phenomenon among women in war conditions. The results of the analysis and generalization of scientific sources are presented in this paper. It has been identified that the problem of anxiety and aggressiveness is one of the topical issues of modern psychology. The need for timely identification and work with the anxiety, anxious behaviour and aggressiveness of women in war conditions and after military aggression has been emphasized. The analysis of the questionnaire conducted among Ukrainian women in war conditions has been carried out, and the degree of their influence on women’s daily lives and life activities in war time has been determined. The purpose of this work is theoretical substantiation and empirical study of the specific of the relationships between anxiety and the manifestation of aggressive behaviour of Ukrainian women in war conditions. The object of this study is the anxiety of Ukrainian women in war conditions, whereas the subject of this study is the character of the relationship between anxiety and the manifestation of aggressiveness of Ukrainian women in war conditions. The conceptual hypothesis of this research lies in the assumption of the presence of significant relationship between anxiety and the manifestation of aggressiveness of Ukrainian women in war conditions, and it has been fully confirmed. Considering the influence of war conditions on the anxiety and aggressiveness of Ukrainian women, the relationship between the mentioned psychological categories has been claimed. It has been revealed that the state of anxiety can be manifested in the aggressive behaviour of women in war conditions. It is noted that the state of anxiety and aggressiveness is the most common phenomenon among women in war conditions. According to the results of this study, there have been identified those significant relationships between indicators of anxiety and certain forms of aggressiveness among Ukrainian women in war conditions. It is substantiated that the high level of manifestation of anxiety is caused by certain psychological features. It has been found out that the increase in the level of anxiety, indicators of family anxiety and anxious behaviour is associated with an increase in the level of aggressiveness of Ukrainian women. The practical significance lies in the fact that the obtained results can be used by employees of psychological services, practical psychologists during counselling at various stages of psychotherapeutic work with women in war conditions.

Two texts by A. Rimbaud, published in 1886, but written earlier, and not poems by G. Kahn, J. Laforgue or J. Moréas, are considered the first vers libre in French. The paper shows two approaches to the analysis of free verse rhythm: the rules for reading and counting silent [Ə]; free verse is considered as a derivative of verse or prose, respectively (K. Scott and M. Murat), which proves the fundamental ambiguity of this poetic form and the importance of the reader’s perception in the process of reading as co-creation. The arguments of opponents and supporters of free verse, the so-called “free verse controversy” (“querelle du vers libre”) prove that in the imagination of writers there exists the connection between the poetic system and the social order. The paper considers the opposition proposed by the French researcher M. Murat — that of the national French vers libre and the international free verse that goes back to the American, that is to say Whitman’s model of Whitman through Valerie Larbeau’s poetry. The creative act of Larbeau, who created a heteronym — the English-language poet Barnabooth, raises the question of erasing national prosody and switching the linguistic code.

“A Tree of Night” is probably Truman Capote’s most terrifying piece, which, along with “Miriam”, has become his signature story. Created in 1943 and published two years later in Harper's Bazaar, this story was called a “pure distillate of terror” by reviewers. Despite the absence of the manuscript in Capote’s archive and his silence about how and when this story was written, the paper pieces together the writer’s personal circumstances during that period. Based on these data the paper makes a suggestion on when the story might have been created and identifies the archetype of the mysterious character named the Great Pasha. This information corrects a number of inaccuracies contained in Capote’s biography published by Gerald Clarke in 1988. The paper explores in detail the history of the Great Pasha — “a fakir from Egypt”, who toured American South with a bold performance “Buried Alive”. According to the hypothesis made in the article, it was the Great Pasha who met six year old Truman at his aunts’ house in Monroeville in May 1931. Twelve years later Capote drew on his memories of the Great Pasha and his assistant Madame Flozelle to create sinister characters of his Gothic story “A Tree of Night”. Thanks to the archival materials the paper managed to bring out the traits that Capote’s characters owe to their archetypes, and to reconstruct the facts of the fakir’s life. For the first time in Russia the article reproduces a unique picture featuring the Great Pasha, his assistant, and the writer’s mother Lillie Mae Faulk.

In 1949 Maria and David Burliuk made a trip to France “following Van Gogh” in order to restore the memory of the French painter's stay in Arles. This trip was embodied in a series of Burliuk’s paintings and in the text Journeys available in Russian (handwritten manuscript) and in English (magazine publication). The paper considers author’s narrative strategies in both versions of the travel journal; special attention is paid to the subjective organization of the text. One can hear the voices of Marusya Burliuk as well as her husband’s although she employs the author’s we. Complex narrative structure of the text is construed with a number of techniques, the most important one being switching of point of view. The paper focuses on the goals of the journey that were set by the travelers and on the ways they were reflected in the text. It is shown that the trip to France, first of all, was aimed at strengthening Burliuk's reputation as an “American Van Gogh”, and, next, at commemorating the French painter and preserving his heritage. The publication in the magazine Color and Rhyme is a unique complex work based on the interaction of both visual and textual material, it includes ekphrases, literary allusions, an epistolary, reprints of materials from the press, American reviews of the Burliuk’s works, etc. There are lots of descriptions, genre scenes, literary portraits, masterfully created by Marusya Burliuk in the published version of the journey, while on the handwritten version reflects private, intimate aspects of the journey (letters to the family).

The article focuses on the two great figures of the XX century, Bernard Shaw and Albert Einstein. Their occupations belonged to quite distant realms of science and fiction, and the only event that united the two in public consciousness was Shaw’s speech in honor of Einstein at the OTR fundraising dinner at the Savoy Hotel on 28th October 1930 where he bestowed the honorary title of “Maker of the Universe” upon the scientist. However, these two great men had much more in common than it is generally accepted. The paper presents some little-known details of Shaw — Einstein relationship, establishes a correlation between their views on a number of socio-political, scientific, philosophic, ethical and aesthetical issues including common grounds and principal differences in their attitude towards the USA and the American social structure. Apart from the few existing articles in the foreign academic journals, this research relies on the official European and American press records of Shaw’s and Einstein’s speeches, their private correspondence, diary entries, memoirs and (auto)biographies created by their close friends, colleagues and contemporaries (such as Beatrice Webb, Leopold Infeld, Ronald Clark), as well as Einstein’s essays and Shaw’s dramas. Another significant figure in the paper is the American writer and scientist Archibald Henderson who, according to professor W.L. Phelps, was “perhaps the only living man who can talk on their own level with the two greatest intellects of today, George Bernard Shaw and Albert Einstein.” The vast majority of documents, radio and video addresses cited in this article have not been translated into Russian; the paper is a pioneering study in Russia, where this topic remains unknown and haven’t so far attracted attention of the Russian academia.

In this paper we have analysed a graphic novel “Maus. A survivor tale” by Art Spiegelman as well as some variants of its translations in the framework of theory of multimodal discourse analysis (ADM) (O`Halloran). The article focuses on analysing the corpus of investigation on its language and nonlanguage level. The aim of the research is to explain in terms of the multimodal discourse analysis theory of main principles of graphic novel translation while observing the way of source language graphic novel transmutation and reconstructing its architecture in the target novel. The methods having been applied in the present paper are those of linguistic observation and description, empiric comparison of translation variants and translation results analysis using ADM tools. Applying methods of ADM in the process of analysing graphic novel results from the necessity to respond to the main challenges of ADM theory for the studies in theory and practice of translation, as well as semiotics and general linguistics. The objectives of the article are to outline the iconic-textual structure of the graphic novel under the analysis, to characterise the visual level of the investigated graphic novel, to generalise arising problems to the translator. The concept of multimodality derived from semiotics is being studied in the article explaining the reason for applying the multimodal approach in the study of the graphic novel. Modalities represented in the graphic novel on non-language level are systematised through different types of multimodal phenomena and their relevance for target text meanings transcreation is described. Both visual and language modalities, which are important for the construction of the meaning, are focused attention to and the multimodal phenomena are piled and systematised in the article. The relationship between the visual and written modalities are discussed and the role and importance for the translation process are explained. Until now there are different investigations of the Maus, but there is no investigation from the multimodal perspective. The investigators focuse on the discursive and pragmatic part, as well as on the expressive value of the work, compare the characteristics of the translation; draw attention to the problems of the literary style of the work Maus; study the role of images in the creation of the work. However, there is still no study of graphic novels from the perspective of multimodal discourse analysis. By means of a series of operations of translation techniques the original text is reconstructed in the translation variant. It involves compressing or widening of the original text, removing inconsistencies between different modalities, reinterpreting “language shell” so that a semiotic content could be preserved and the author’s message transmitted without corruption, for that redrawing some characters or chapters, removing, or replacing some visual symbols with different ones. Illustrative material shows a certain logic scheme to follow the process of translation taking into consideration different multimodal phenomena, as well as the absence of some of its constituents. On the one hand, extralinguistic objects engraved in pictures of the graphic novel may present the reason for the translation technique of addition, and on the other hand the absence of some details in the pictures may justify the translation technique of omission. Evaluating functional types of multimodal phenomena also may lead one to adequate selection of synonyms or a phrase to choose in a process of translation having as a “guide” visual image supporting language level of a graphic novel. The term “graphic novel” is specified as well as the difference between terms “comic” and “graphic novel” is outlined. Graphic novel format is proved to assimilate to the literary novel with the content of memoirs, autobiography, history, documentary reports etc. Maus is the first graphic novel dealing with Holocaust theme aimed at the adult audience. According to the definition of the graphic novel, Maus is seen to share discursive mechanisms with visual narrative instruments, embedded in multimodal phenomena. The types of multimodal phenomena are selected in the present investigation and grouped with illustrative examples taken from the corpus. In the framework of ADM theory, the selection of translation techniques and operations are justified, and the reasons for certain translation variants are explained. As it is shown in the paper, graphic novel translation differs from literal one. The most important characteristics of graphic novel translation distinguishing this genre of literature have been outlined: 1) the graphic novel translation unit obligatory consists of both verbal and visual parts; 2) the intonation of the characters of the graphic novel is a part of a style and is taken into consideration in the course of translation; 3) visual part of the graphic novel is presented by multimodal phenomena that influence the strategies of translation. General recommendations for the translation of the historic graphic novel have been given, mainly: 1) for the purpose of collecting information from the visual part. It is recommended to read and discover the entire content of the novel before starting the translation, paying attention to the multimodal phenomena and their types mentioned in this article. Attention is paid to past events, other extralinguistic meaningful objects. An individual language style is translated with the same style and is maintained throughout the text; 2) on the language level, it is recommended to choose at least the sentence as the minimum translation unit of the graphic novel using substitution techniques within the unit as long as the final sentence reflects the same message. However, the largest translation unit can be chosen. Appropriate options are a speech bubble (speech bubbles) or the entire page. Bubbles (speech balloons) often contain colloquial speech, which differs much more between languages than literal text of a book. The ease of colloquial speech is nearly impossible to achieve without the freedom to change the order, composition, and number of sentences. Often, it is not the character-specific phrases that need to be translated, but rather the emotion of outrage or joy, recreating it using the character’s language (such as the speech of the immigrant, the main character, Vladek, or his wife); 3) the use of bold. It is understood that it is not necessary to use bold type in the same units that appear in the original. The most important thing is to convey the same meaning and intonation in the translation avoiding the “word for word” translation; 4) the language style of the author and the characters. The author and the characters of the graphic novel have their own language style, which is part of the meaning. Characters may have their own characteristic expressions and circumstances that explain the choice of phrase translations. After reading the text and visualising the novel, it becomes clearer what type of the target text of the protagonist should be created to remain truthful and sound natural; 5) “Litmus paper”. It is recommended to read the translation after a couple of days without looking at the original text thinking about whether or not the author would choose the same words, style, intonation; 6) Culture references create a certain atmosphere and are translated (6.1) literally as in the example of gefiltefish translation or (6.2) simplification is used the culture in case of translation of the same unit into Russian рыбафиш; 7) translation of anthroponyms and proper names. It is not recommended to translate the proper names of the historical graphic novel taking into account the documentary part of the novel. The same variants of anthroponyms are maintained throughout the text; 8) accuracy is the second priority after avoiding meaning corruption. One should try to preserve accuracy if it is possible, respecting the condition of preserving the meaning without corrupting it. To achieve the effect of equal perception of the novel by the reader both in the original language and in the translation language, two things are needed: understanding what is said in the original text and reconstructing it in the target text. The ADM theory, in this respect, is the tool to achieve the most adequacy and the most accuracy at the same time.

The paper is aimed at filling the gap in learning the formative image peculiarities of the English and American Imagistic poetry by analyzing the correspondence of the internal and the external and their correlation. This is where the answer lies, why T.S. Eliot called Imagism “an opening salvo” of English/ American Modernist poetry. It also explains the reason for a long-term effect of this short-term “school” in the English poetry of the twentieth century. Imagism hasn’t left any extended or profound theory as far as the criteria for producing “hard, dry images” (T.E.Hulme) are concerned. Since then the problem has been under-studied and calls for more in-depth analysis. The modern theoretical background of the paper includes the ideas of S. Averintsev and M. Gasparov, Paul Ricoeur and Gaston Bachelard; the criticism of the Imagism founders (T.E. Hulme and E. Pound) as well as its present-day English and American researchers. The major theoretical points highlight the important features of image transformation in Imagism: the dual (semantic and psychological) nature of an image (P. Ricoeur); loss of its axiological constituent thus forfeiting its wholeness (M. Girshman); its non-permanent essence (G. Bachelard). All these “new” sides underlie too general and vague definition of an image as “an intellectual and emotional complex in an instant of time” given by Ezra Pound, his definitive denial of using images as “ornaments” and the emphasis on the image affiliation with speech, not language. The fight doesn’t have to be limited only to opposing Romanticism (as in Hulme’s “Romanticism and Classicism”). Equally significant and far more sophisticated is the distinction between Symbolic and Imagistic essence of an image (Pound’s “Retrospect” and “Gaudier Brzeska”). For Pound, the main criterion is the receptive potential of an image, its semantic openness which offsets its meaning as finally fixed in some symbol. The paper examines the possibility to apply Roland Barthes’s idea (“L`imagination du signe”, 1962) of the crucial influence of the interior (symbolic) relationship and two exterior (paradigmatic and syntagmatic) relationships on the formation of both single image and the total imagery of a certain type of art conscience – consequently, of Symbolism, Romanticism and Imagism. In the early period of Imagism development (the poetry of F. Flint, E. Storer, to a lesser extent, of T.E. Hulme) the images still preserve the inner affinity with the signified objects (concepts) as seen in Romantic and Symbolic image “patterns”. And throughout Imagism development, this inner affinity is being weakened until a distant outer resemblance is left. It is clearly seen in Hulme’s “Autumn”, Pound’s “In a Station of the Metro”, H.D.’s “Oread”, “Hermes of the Ways” et al. The close reading of the W.C. Williams’s poem “The Red Wheelbarrow” is carried out in front of the “Tall Nettles” by Edward Thomas (1878–1917), his contemporary, who is now considered to be one of the “non-Modernist modern” poets. It is stated that the central image of the red wheelbarrow in its every detail constitutes a modern pastoral while Thomas’s nettles stand for psychological matrix of personal melancholy and despair. Syntagmatic relations also involve the further interaction of signs in the form of “superposition”, forming montage as one of the important Мodernist techniques not only in poetry, but also in Мodernist prose. And it becomes evident that it is not a mechanically borrowed cinema technique, as it is commonly viewed, but a deeper, “syntagmatic” similarity. The result of the research, based on the analysis undertaken, seems to prove its initial point: the poems of T.E. Hulme, Ezra Pound, W. Carlos Williams, Hilda Doolittle (H.D.) taken as models, manifest that the image in Imagism is every time constructed as a new actual syntagma of the common imagination of a poet and a reader to become the unique image for every single poem without its further “universal” use in any virtual paradigm.

Introduction and purpose of the work. Aesthetic medicine currently has many methods to keep our skin in the best possible condition, and one of these methods is the use of tissue stimulators. The purpose of the following paper is to analyze, present and apply tissue stimulators in anti-aging prevention. Review methods. The paper is based on a review of literature about tissue stimulators, aesthetic medicine and anti-aging therapy. Most of the publications used were from Pubmed and Google Scholar electronic databases. State of the art description. Aesthetic medicine is a department that over the past few years has been closely associated with the slowing down of skin aging processes. In humans, over the years, proliferative processes slow down, the rate of collagen and elastin degradation increases, and the intercellular matrix is reduced. Substances known as tissue stimulators used in anti-aging therapies mean that the above processes can be delayed. Conclusion. The expectations of patients visiting aesthetic medicine clinics regarding activities that improve their appearance are increasing. They are unable to accept their own aesthetic defects, which is why they often strive for unnatural effects. Tissue simulator treatments can be a valuable way for patients to maintain healthy and rejuvenated skin.

Introduction: Xenotransplantology, the field of transplantation involving organs or tissues between different species, holds great promise for addressing the global organ shortage crisis. However, the development of new technologies without proper legislative preparation raises significant moral and ethical considerations. This paper provides an overview of the current state of xenotransplantology, highlighting its revolutionary potential alongside the moral dilemmas it entails. Aim of the study: The aim of this study is to assess current social, ethical, religious, and legal trends regarding the issue of xenotransplantation. Materials and methods: To obtain up-to-date information concerning trends in xenotransplantation, a review of the PubMed and Google Scholar databases, along with the latest legislative reports in both Europe and Poland, was performed. Conclusions: Firstly, the authors briefly report on the current situation concerning transplantology and the widely spread organ donor crisis. Next, the issue of species boundaries and the moral status of non-human animals is addressed. The assessment of ethical implications of utilizing animals as organ donors is examined, along with the legal acts regulating this issue. Moreover, the authors attempt to evaluate the cultural and religious differences related to this concern. Furthermore, this study discusses the allocation and distribution of xenotransplants, considering issues of justice, fairness, and access to this innovative medical technology. Lastly, the paper delves into the risks and uncertainties associated with xenotransplantation, including the possibility of cross-species disease transmission and intensified course of organ rejection disease.

Introduction and Purpose: Coeliac disease is an increasingly prevalent disorder worldwide. It is estimated to affect about 1% of the population and its symptoms heavily impact people's lives. The aim of this paper is to delve into the topic of coeliac disease and present basic information about its origins, current diagnostic methods, and the challenges associated with its treatment. This article includes all the necessary information from up-to-date sources. State of Knowledge: Coeliac disease was discovered a long time ago, but it is still not completely understood. Every year, new research is published regarding different populations in various countries. While we know more about the disease, its symptoms, and causes, we are still far from fully understanding all the inflammatory processes occurring in the human body. There is solid evidence that this enteropathy is caused by gluten, and the only way to reduce the clinical manifestation of coeliac disease is to adhere to a gluten-free diet. However, some patients do not benefit from this type of diet and still suffer from coeliac disease. New drugs currently being developed offer hope for these individuals, as they attempt to target the immunological reaction and mitigate the immune response in the small intestine. Conclusion: As approximately 1% of the population suffers from this disease, it is crucial to diagnose patients in the early stages of its development. Early diagnosis can prevent the development of other disorders that coexist with coeliac disease, which can be particularly dangerous, especially for children. This paper provides up-to-date information about the clinical manifestations of the disease, as well as methods of diagnosis.

This article focuses on the promotional aspects related to the tourist attractiveness of the neighboring countries-Poland and Slovakia. The purpose of the article is to analyze the issue in question and point out the importance of the search for ways to increase the effectiveness of management of the area of tourism promotion in both countries. The authors used an empirical research method with quantitative-statistical and qualitative studies on specific promotional campaigns. The Olympic Games have the greatest marketing potential among sporting events, as the most important sporting event in the world. The possibility of organizing such an event in Poland and Slovakia would certainly serve to improve the recognition rates of both countries. The authors will try to demonstrate this potential as part of the considerations in this article. Acknowledgement: This paper was supported by the project NP-KSV-ET-01-2023-12/ST - International cooperation in the field of development, management and law in tourism and sports between the Republic of Poland and Slovak Republic. The views expressed in this paper are those of the authors and should not be taken as reflecting the position of any authority, entity or institution. This article presents the legal status as of 25 March 2023.

The ‘migration’ of concepts from one language to another, which takes place in cultural exchange, frequently gives rise to changes in the target language, primarily involving the lexical field. The reception of the Romanist legal tradition in China has led to the formation of a specialized lexicon which, along with the translation and production of Roman law-related works, has been subject to constant growth. This kind of terminological transposition has often resulted in the emergence in Chinese of more than one translatant for the same Latin word. As a concrete example of this phenomenon, this paper aims at providing a synoptical overview of the rendering in Chinese of the concepts of dolus and culpa, two legal institutions also largely connected to the field of commercial law. The sources analyzed from a diachronic and contrastive perspective range from the earliest manuals of Roman law published in China at the beginning of the twentieth century to recent documents, translated or directly composed in Chinese. More specifically, this paper will try to answer the following questions: what is the historical evolution of the main terms used in Chinese to express the concepts of dolus and culpa? What are the criteria adopted by Chinese translators/authors in choosing these terms? What are the main features and issues related to the linguistic rendering of the two legal institutions? As for the results of this study, attention will be paid to one of the peculiarities of the linguistic rendering of the concept of culpa, that is the use of two different translatants: guoshi 过失 and guocuo 过错. At the same time, another aspect on which this paper will shed light is the existence of a plethora of translatants related to the concept of dolus (qizha 欺诈, guyi 故意, zhaqi 诈欺, etc.). In this sense, on the one hand, it will be shown how the presence of multiple translatants is acceptable and useful when they are used to express the different shades of meaning conveyed by dolus and culpa that cannot be rendered by means of one single translatant for each of these two notions; on the other hand, this paper will highlight the necessity of a higher homogeneity and standardization of the Chinese Romanist lexicon.

The professional activity of a specialist in modern society is primarily determined by their ability to make competent information interactions. Definitely, information is one of the main resources for the scientific, technical and socio-economic development of society. It plays an important role in the process of educational space modernization where the formation of the ability to find, analyse and process this information takes on special importance, requiring the development of innovative approaches to the research competence shaping future Ph.Ds. in their postgraduate studies. The article is aimed at substantiation of methodological approaches to solving the problem of building research competence of future Doctors of Philosophy during postgraduate studies. The objectives of the paper are to define the meaning of the basic component of the article – “approach”, to analyse the fundamental approaches that provide building research competence of future Doctors of Philosophy as well as to substantiate the expediency of their use. Complex methods for solving the problems of a scientific paper have been used, including theoretical analysis and synthesis of ideas, results, theoretical statements (explained in scientific literature), generalization and systematization of the results of available investigations of the highlighted issue. Study results. The modern educational system focuses on building future specialists’ competence as a result of their readiness and ability to solve educational problems and carry out research activities. The present paper is devoted to the problem of training future Doctors of Philosophy during postgraduate studies because the transmission to new educational standards significantly increased the relevance of the problem of building research competence that determines a lecturer’s ability to investigate, plan and organize his /her work effectively to achieve the predicted result. The analysis of scientific and pedagogical studies established the conceptual core of methodological approaches to building future specialist’s competence during postgraduate studies. In order to have the holistic view of research competence, its structure and meaning, as well as the laws of its development in relation to future Doctors of Philosophy, fundamental methodological approaches have been systematized, namely acmeological, systemic, cluster, personality-oriented, technological, axiological, competence-based, praxiological, facilitative, participatory, synergistic, meta-subject, and hermeneutic ones. Taking into account the development of new standards and the features of educational paradigms that provide the effectiveness of building research competence of future Doctors of Philosophy, the above mentioned complex approaches have been considered as basic and optimal ones. The analysis of best practices clearly shows that there is no common vision of the principles of combining methodological approaches in solving the issue of building research competence. The article presents the experience of combining methodological approaches in solving the issue of building research competence based on the principle of mean full dominants. The author has found out that the use of these approaches will provide the successful process of building research competence of future Doctors of Philosophy, their ability to create fundamental scientific developments focused on the shaping of educational space that will develop and improve the personality qualities of future Doctors of Philosophy for successful self-realization.

The paper deals with a comparative and contrastive analysis of the experience Azerbaijani and Turkish languages have gained in the transition to the Latin script. The methods of rendering personal names from European languages which, similarly to Azerbaijani and Turkish, use the Latin alphabet into the specified Turkic languages and vice versa are considered. The author presumes that the way a problem of rendering personal names as a special category of proper names is solved provides the grounds for giving an opinion on how successful the integration of a language that has switched to a Latin-based alphabet into a family of languages and cultures sharing the similar Latin alphabets has been or is going to be. In this respect, the study is topical since it enables one, by considering similar experiences of the languages involved, to forecast the trajectory the Kazakh language, intending to switch to the Latin-based alphabet in the near future, is going to follow. The novelty of the study consists in the linguistic forecasting method applied, which implies solely the study of the real experience of the languages subject to study and therefore provides the forecast with one hundred percent verifiability to be achieved once Kazakhstan has entirely transitioned to the Latin script. The theoretical value of the research consists in a contribution it makes to the methodological basis of the comparative and contrastive studies of related languages, including the creation of alphabets for them, as well as in a possibility of making use of the results achieved herein in further studies aimed at theoretical comprehending the peculiarities of a language functioning in the translation aspect after its transition to a new alphabet. The study has made it possible to identify the methods of rendering personal names from/to European languages, used nowadays in Turkish (absolute and relatively complete transfer) and Azerbaijani (transcription and transliteration) languages. Through the prism of practical experience of these languages, an objective forecast is made with respect to the Kazakh language in case of its complete transition to the Latin-based alphabet. The paper concludes that the Kazakh language has reasons to follow either the way of Turkish, as the language of the state, which to a certain extent has managed to successfully integrate into Europe in cultural, economic and political terms, and what Kazakhstan certainly strives for, or the way of Azerbaijani, to which the Kazakh language is connected with ties of a shared cultural and historical past.

The paper is concerned with some aspects of politeness in the request act by the pragmatic connotations of syntactic structures in Hindi and Persian. Considering the role of politeness as an explanation for the deviation from the Grice’s cooperative principle, the main question of the paper is whether Leech’s maxims of politeness operate on the syntagmatic and paradigmatic relations and whether there is any hierarchy in their manner of application. To answer the abovementioned question the main hypothesis of the research posits that Leech’s maxims of politeness have a structure of hierarchy in both Persian and Hindi. Considering the Pandharipandes' (1979) hierarchy of the degree of politeness proposed for Hindi, this paper aims to develop a similar hierarchy of the degree of politeness for Persian and to analyze the Leech’s maxims operating in the respective hierarchies of politeness. The general theoretical framework adopted for the present study is based on Lakoff (1972), and Leech (1980). Whereas the findings of this research indicate a hierarchy in Hindi and Persian at the syntagmatic planewith regard to their respective Leech’s maxims,no such hierarchyis detectable for paradigmatic relationwhichholds good for all types of social situations.

This academic article offers a model of the English-Ukrainian sub-corpus of texts of official and business documents of NATO, UN, and WTO (hereinafter referred to as the EUS) as a supplement to the Ukrainian National Corpus (hereinafter referred to as the UNC), where texts are presented as a hierarchical structure. In an effort to provide a more comprehensive view of NATO, UN, and WTO official and business documents, a mechanism of use of our model envisages determination of the exact position of a text in all UNC corporas, what essentially simplifies the practical process of search and automated translation of texts and special terminology in particular. In consequence, the author offers to increase the number of unique texts that will ensure the representativeness of the EUS in the Ukrainian National Corpus, and to divide the whole process of the EUS formation into elementary tasks that will increase the UNC efficiency. The practical value of the research lies in a possibility to use the EUS for texts parallel translation and terminological phrases separation on the basis of such texts. The methodological potential of our research is based on the works of well-known Ukrainian and foreign scholars (V. Bohorodytskyi, I. Baudouin de Courtenay, K. Brugman, W. Wundt, B. Delbruck, G. Paul, O. Potebnia, P. Fortunatov, W. Scherer, H. Steinthal, A. Schleicher et al.), who strengthened the scientific interest to the problem of translation and corpus of texts in particular. The object of the research is a model of the English-Ukrainian sub-corpus of texts of official and business documents of NATO, UN, and WTO. The purpose of the research is to prove that the model of the English-Ukrainian sub-corpus of official and business documents texts can become a full-fledged informational foundation for the formation of texts parallel corpus within the Ukrainian National Corpus. The methods of observation and experiment were applied to analyze empirical, review, conceptual analytical tools that specify the meaning of described objects and phenomena given their qualitative affiliation to the UNC. The study focuses on a number of tasks, in particular: - to determine a theoretical and linguistic basis of the concept “English-Ukrainian sub-corpus of texts of official and business documents of NATO, UN, and WTO”; - to determine the mechanism of updating of the English-Ukrainian sub-corpus of texts of official and business documents of NATO, UN, WTO within the UNC; - to find out the specifics of formation and filling-in of the EUS; - to substantiate the relevant methodology of examination of official and business texts of NATO, UN, and WTO in the English-Ukrainian sub-corpus of texts of official and business documents; - to single out and itemize the advantages of the English-Ukrainian sub-corpus of texts of official and business documents of NATO, UN, and WTO within the UNC. Analysis of the English-Ukrainian sub-corpus of texts of official and business documents of NATO, UN, and WTO as a construct of the parallel corpus of texts of the UNC was carried out in several stages. The first stage envisaged description and inventory. Theoretical works on the history of the Ukrainian National Corpus were reviewed and generalized, and the concept of “English-Ukrainian sub-corpus of texts of official and business documents of NATO, UN, and WTO” was determined. It was found out that the UNC is the object of research in such areas of linguistic studies as the applied and corpus linguistics that construe the corpus of texts as a translator’s tool. This encourages us to highlight the advantages and disadvantages of the UNC and justify the expediency of our proposal to develop the English-Ukrainian sub-corpus of texts of official and business documents of NATO, UN, and WTO. Definition of the UNC as a national corpus of texts that contains only Ukrainian texts and does not envisage a parallel translation evidenced the need to create a proposal of a parallel corpus of texts with an updated English-language database. The selection of lexical items with the official and business semantics is based on documents of international organizations, such as NATO, UN, and WTO. At the same stage, we determine the purpose of the research, in particular, the formation of the English-Ukrainian sub-corpus of texts of official and business documents, which envisages a parallel translation of NATO, UN, WTO texts. This sequence of procedures allowed us to carry out consideration and interpretation of existing theoretical provisions and inventory of factual research materials. Theoretical and corpus analysis methods were used in the research. The second stage envisaged analysis and differentiation. Special aspects of filling-up of the EUS with official and business texts of NATO, UN, and WTO were characterized. Theoretical analysis of the EUS was carried out in order to establish a clear hierarchy of the UNC structure. The main types of participants of the EUS formation (students, teaching staff) were differentiated and the behavioral model of every participant in the process was developed. The specifics of presentation of the English-Ukrainian sub-corpus of texts of official and business documents of NATO, UN, and WTO in the UNC was established. This final stage, where methods of observation and experiment were used, evidenced determination of an exact place of a text in the EUS (belonging to a certain category of homogeneous texts) that becomes a crucial factor in choosing a translation option. Numerous terminological phrases and expressions in the analyzed official and business documents of UN, NATO, WTO, which act as identifiers in the EUS, were systematized. An increase in the number of unique texts (official and business texts) was noted, which ensures the representativeness of not only the English-Ukrainian sub-corpus of official and business documents texts, but of the UNC in general. The final stage of the research confirmed the expediency of the division of the whole process of sub-corpus formation into elementary tasks. We generalized the statement that the EUS is a dynamic, context-dependent sub-corpus (only official and business texts of international organizations, such as NATO, UN, WTO) and an optimal algorithm designed to be easily downloaded and used. Conclusion. The analysis conducted in the present paper is meant to illustrate a new approach to forming a modern model of the sub-corpus of texts of official and business documents. The model of the English-Ukrainian sub-corpus of official and business documents texts of NATO, UN, and WTO provides for a clear division into categories of homogeneous texts and a quick search for special terminology of international organizations, such as NATO, UN, and WTO, in the EUS. In the context of the texts analyzed in the current paper numerous separated words and expressions-identifiers can help to carry out search and refer to a relevant text in the sub-corpus. Compilation of terminological nominations glossary, their functional and stylistic labeling and assimilation into the commonly used vocabulary of the EUS and later on in the UNC are currently at the stage of formation and approval. To this end, the current research manifests the concept of the EUS as a sub-corpus of the UNC that allows the prompt presentation of relevant texts of the official business style and coverage of the broadest range of interested readers.

The article aims to study the poetics evolution of a great Polish poet and prose writer, Nobel prize winner Czesław Miłosz towards a fundamentally new comprehensive literary form: from “Piesek Przydrożny” (“Roadside Dog” 1997) to “Abecadło” (“Milosz`s ABC`s” 1997) and “Inne Abecadło” (“A Further Alphabet” 1998). The purpose stimulates the usage of the analytical, hermeneutics and receptive methodology, as well as textual analysis. It is stressed that the years of this work publication indicate the writerєі success in his determined search for a form that would be capable, containing immense life material, countless events, lives and artistic-philosophical reflections, to create the picture of the 20th century. The paper highlights why “Piesek Przydrożny” does not meet any requirements for containing the unlimited number of life facts within a text. We’ve noted the organizing function of Piesek in the system of a fictional unity. Moving freely, Piesek made it possible for Miłosz to create a certain series of philosophical pieces (“Ubóstwo wyobraźni”, “Wzniosłość”, “Pieśń dziadowsku”, “Со upadek”, “Powieść”, “Gombrowicz”, “Polski literat”) and several tragic essays – “Ojcowskie kłopoty”, “Zmartwienia historyka” and others. It is proven that while the form of this book contains a variety of material, it still cannot give Miłosz the absolute freedom he was striving for. The writer was determined to find the form which would, according to him, “allow for much freedom”, “not pursue beauty but just register facts”. Considering Е. Brazgovskaya’s findings, the productivity of the alphabet (аbecadło) is proved. The paper expresses the idea that one can treat the alphabet (аbecadło) as a kind of a memoir genre. The innovative structure of “Abecadło”, consisting of essays-novels, is analyzed. The article traces the associative connections which cement 200 essays into a single entity, creating the image of the epoch.

The paper offers the comparative study of two poems: Paris by Hope Mirrlees (1920) and The Waste Land by T.S. Eliot (1922). The research aims to consider Paris as one of the key works of modernist poetry and a possible model for The Waste Land. The author of the paper turns to some parallels confirming the similarity of these two poetic texts. Particular attention is paid to the “anthropological” or “ritualistic” mode of both poems. The philosophical concept and poetic structure of these poems were based on the ideas presented in the books and research papers by the representatives of Cambridge anthropological school (J.G. Frazer, J.E. Harrison, J.L. Weston, etc.). Both poems could be considered in the context of modern anthropological and psychoanalytic theories. The ritualistic mode of the texts not only provides scientific grounds for the embodiment of personal and collective experience in poetry but creates a powerful vital impulse inherent in those archaic rituals, the elements of which were reconstructed by the poets. The works of J.G. Frazer, J.E. Harrison, J.L. Weston, and others help the readers to comprehend and expand the content of certain episodes, clarify “dark” places, to see a harmonious poetic structure and sophisticated concept of the world order, civilization and man behind the external arbitrariness and fragmentation. Both Paris and The Waste Land became manifestations and embodiments of the “mythological method” articulated by Eliot in 1923.

The paper examines in detail the history of the creation of “The Love Song of J. Alfred Prufrock”, as well as the methods of its research in Western and Russian literary studies. The author proposes to combine a careful reading of this text with the notion of this poem as a spiritual autobiography of Eliot, which has various dimensions: from personal, proper poetic to esoteric. Based on the analysis of the biography of the young Eliot, the poet's relationship with J. Verdenal, the history of the poem, the drafts, the final text, the title of the poem, the epigraph, the poem's place in the poet's work, Eliot's statements about “Prufrock” the paper identifies the parameters of the symbolism of this work, which, playing on Eliot's complex relationship with the inexpressible (having an ambivalent nature), extends to its composition (the relationship of “I” and “you”; the paradoxical nature of the ending), the system of images and motifs (Prufrock as a theatrical person, the opposition of the male and female world), the special sense of reminiscences from Dante, Shakespeare, Goethe, Walter Pater, Oscar Wilde, the philosophy of creativity as a mystery (Prufrock as a poet, combination of eroticism and mysticism, the theme of sacred crime) and love (homoerotic theme), genre (elusiveness of genre, Faustian beginning in it), symbolism and esoterics (“Prufrock” as a Masonic text on initiation, on life as theatre). The author gave a special place to the concretization of ekphrases (Michelangelo, Leonardo da Vinci, Burne-Jones), the content of which confirms the thesis that the poem has a text in the text.

The paper attempts to build an integral system of myth and determine its poetic function in the literature of the first half of the 20th century. There are a huge number of approaches to the study of myth as an unconscious symbol, but a myth becomes a literary phenomenon only when it is purposefully used by the author as part of his creative vision. Remythologization or the conscious return of literature to the original sources and archetypes in the work of W.B. Yeats, T.S. Eliot, J. Joyce, and others are part of the poetic innovation of an entire literary era. The article briefly traces the history of remythologization, and the name of T.S. Eliot stands out as the first to state and fix a new attitude to myth (“‛Ulysses’, Order, and Myth”, 1923). Myth, according to Eliot, is not an unconscious “force” of the writer's creative imagination, but is conceived as a poetic category, as a means of recreating the aesthetic orderliness of a work from the chaotic reality. Conscious mythologization is also conditioned by the need to synthesize several heterogeneous creative structures in a single artistic whole. The reader conceives the presence of a myth in a literary work through the association of imagery with extra-textual plots, thereby fulfilling the author's intention. The paper, using the example of Four Quartets by T.S. Eliot and “The Wheel” by W.B. Yeats, shows how the suggestive archetypes and the variety of reader associations contribute to the timeless perception of the text (reading does not last in time, it is extremely generalized, cyclical, integral). All poetic means of remythologization are aimed at such a synchronous perception of the artistic time and space of the work, which acquires a mythologically universal character, becomes an artistic model of the world.

The paper is dedicated to the poem by T.S. Eliot Four Quartets (1943), it examines its artistic specificity, its poetic and musical peculiarities with their complex symbolic subtext and a whole layer of meanings. The organizing principle of the Four Quartets is the synthesis of myth and melos. The poem contains features “borrowed” from music so that the “musical energy” (melos) that is not yet a melody finds a specific poetic embodiment. Built on the principles of musical poetics, Eliot's poem contains various artistic images that alternate and combine according to the principle of the development of musical themes (like Wagner's leitmotifs) and their meaning does not remain the same, but is changing. Another similarity between the poem and a musical work is its timeless character: a full perception of the musical integrity of Four Quartets is achieved after repeated reading of the text, simultaneous experience of what has already been read and what has yet to be read — and this is like listening to a symphony, the desire to perceive it in its entirety, beyond time. The myth, in contrast to the quite specific mythologems of The Waste Land, in Four Quartets and its melodiousness, does not have any subject or plot even in its infancy and is rather represented by abstract, general ideas and archetypes. The article analyzes the archetypes and elementary symbols of Four Quartets (circle, square, quaternity, intersecting lines, etc.) and reveals their significance. The paper demonstrates that the imagery of Four Quartets is also based on Eliot's personal impressions, which merge with many “intellectual” associations and, refracting in the mythopoetic structure of the poem, turn into general, universal symbols.

The article investigates works by Octavia E. Butler (1947 –2006), an African-American writer who had a significant impact on the development of science fiction in the USA and the world. The paper provides an overview of Butler’s works and reveals the relationship between the problems and language / style of her prose, the latter being determined by the former. The first part of the paper examines the main topics of Butler’s works and focuses on the problem of survival. Being a disappearing minority, Butler’s heroines are usually isolated from others and, consequently, in order to survive they have to adapt to the circumstances, since resistance is impossible. However, for Butler the survival of an individual is less important than the preservation of the humankind. For Butler’s heroines it is the reproduction of the genetic and/or cultural memory of mankind that make the future possible and guarantee the survival. In the second part of the paper Butler’s works are analyzed in the context of Afrofuturism and it is pointed out that although Butler has much in common with other representatives of this movement, she deals with the projects for building an ideal society in a different way: Butler is skeptical about utopia as a project of a conflict-free society. The final part of the paper examines Butler’s language and style, noting that for her language serves as an impersonal, objective tool of analysis of human behavior. A special attention is paid to Butler’s latest novel Fledgling (2005), in which language serves both as a tool for expression and a topical issue.

The article provides an overview of the 29th international conference “Ezra Pound and Friendship.” The conference was held at Kyoto University from June 24 to June 26, 2022, virtually. The conference was attended by researchers from fifteen countries, including scholars from the USA, Germany, France, Japan, China, Great Britain, Russia (Lomonosov Moscow State University). Two crucial themes of the conference related to (1) Pound's friendships and (2) the Asian, in particular the Japanese dimension in the work of the American poet did not limit its participants in their choice of material. The papers presented at the conference were distinguished by an extraordinary thematic diversity, which made it possible to construct a global context to study Pound. During the conference, a number of papers touched upon Pound's friendship with W.B. Yeats, E. Hemingway, T.S. Eliot, A. Gaudier-Brzeska, B. Banting, Katsuo Kitasono. Several panels were dedicated to Pound's interactions with his younger pen friends. The very concept of friendship in Pound's work, the specificity of its perception by the poet and its closeness to the Neoplatonic, Provencal, Confucian traditions was discussed. A number of speakers turned to the “Cantos” and methods for their study. One of the most important features of the conference was its focus not only on the study of Pound's poetry, but also on the poetry of contemporary authors: according to the established tradition, the closing panel of the conference was dedicated to poetry readings and subsequent discussion.

Oral mucosa is an inner lining of oral cavity, which maintains different functions including protection of epithelial integrity. Pathology of oral mucosa can develop in response to the action of pathogenic microorganisms, viruses, and various traumatic factors; it can be a result of systemic pathology of a patient as well. Pain and discomfort usually accompanies such conditions leading to decrease of patient wellbeing. The basis of the pharmacological regulation of the regeneration process is the stimulation of wound healing. The aim is to summarize and discuss the spectrum of remedy options that are used to stimulate epithelization of oral mucosa. The overall goal of the paper is to provide full and comprehensive information for dentists and their patients about medicament variety, ways of theirs application and dosage. Methods. Relevant literature from MEDLINE (PubMed), Google Scholar, and in open access journals which are published by Elsevier was selected using the following key words «oral mucosa», «epithelization», and «remedy» were used in various combinations by the year of 2023. In total there were found 48 papers. To the selected scientific papers we applied the inclusion and exclusion criteria to choose the relevant ones. Conclusions. A significant number of drugs for the treatment of inflammatory processes in the oral cavity are available nowadays on dental market. Numerous studies substantiates the effectiveness of their use in dentistry. Therefore, when choosing pharmacological drugs, preference is given to drugs with a complex effect, which locally affect various links of the pathogenetic mechanism of the occurrence of diseases and do not disturb human wellbeing.

Endometriosis is a chronic gynaecological disease characterized by the presence of the uterine mucosa that functions in accordance with the menstrual cycle outside of its usual location. This disease significantly reduces the quality of life of women facing numerous ailments, most often pain, and may lead to reduced fertility. The prevalence of endometriosis is difficult to determine due to the complexity and lengthy diagnosis. It is estimated that this disease occurs in 3-8% of women of reproductive age, and symptoms may also appear after menopause. It is worth noting that the relationship between the disease's severity and endometriosis symptoms is often not proportional. The aim of the paper is to present a case report of a 23-year-old female patient with endometriosis, to differentiate the disease from irritable bowel syndrome and to draw attention to the problematic and lengthy diagnostic process due to the multitude of symptoms from various organs. Material and method: Study of an individual case of a patient and a review of scientific articles available in Google Scholar and a review of publicly available textbooks in the field of medicine. The paper emphasizes the need to broaden the knowledge about endometriosis by specialists in many fields of medicine and points to the lack of quick, minimally invasive tests enabling efficient diagnosis of the disease. Increasing the awareness of doctors including other specializations than gynaecology, organizing campaigns to increase awareness of the disease among women, which may contribute to earlier diagnosis of patients, earlier application of an effective treatment, and improvement of patients' quality of life.

Introduction:Lipid disorders are one of the most common modifiable risk factors for cardiovascular disease. Until now, the mainstay of dyslipidemia treatment was the use of widely available statins. These drugs, despite significantly lowering cholesterol and bringing its concentration to desired values were associated with a number of side effects. In addition, the need for daily use of statins is inconvenient for patients and leads to their irregular use and, consequently, failure to achieve the desired effect. The new drug, inclisiran, which is a PCSK9 inhibitor, represents the future in the treatment of lipid disorders. Studies conducted to date have explored the drug's mechanism of action, frequency of administration to achieve the desired effect, and side effects. The results of these studies have confirmed the significant efficacy of inclisiran,which may become a major form of treatment for dyslipidemia in the future. Purpose of the work: This article reviews the state of knowledge based on available studies on inclisiran. The aim of the review is to present the most important information about this drug related to the mechanism of action, effects on the body or assessment of efficacy. Materials and methods: The authors, based on databases such as PubMed, Scopus and Google Scholar, created a paper summarizing a review of currently available publications, concerning a new drug in the treatment of dyslipidemia- inclisiran. The authors searched for available information , using terms under the heading "key words" contained in other scientific papers. Summary Inclisiran is a novel drug that represents the future in the treatment of dyslipidemia. Due to the lack of systemic effect, it has insignificant side effects, and the need for such rare administration will allow to obtain the desired lipid concentrations even in patients who do not cooperate.

The primary purpose of this paper is to determine and prove the impact of loads with different intensities on the treadmill on the heart frequency, as well as to prove the relationship and impact of some anthropometric and motor parameters on the physiological one in the manifest space. In harmony with the purpose of the research, three basic hypotheses have been presented that cover the anthropological research fields. In this paper, 19-year-old students of the Faculty of Sports Sciences are included. To achieve the purpose of the paper, a sample of 80 students who were regular students during the year 2022/2023 was included. Four anthropometric variables, three motor tests (running tests) and four physiological tests (pulse at rest and during loads) are included in this paper. For the three groups of the system of variables, the basic statistical and distribution parameters for each variable, as well as the measures of asymmetry and normal distribution, were calculated. Then the correlations between the variables in the manifest space, as well as the correlations between the system of variables. In order to determine the relationship between predictor variables (anthropometric and motor characteristics) and criterion variables (results of functional skills), regression analysis was applied in the manifest space. The processing of the results shows that the obtained values do not deviate from the normal distribution, which completes their metric characteristics. The impact of morphological and motor factors on heart rate results has not been proven.