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Autosomal dominant polycystic kidney disease (ADPKD) is a genetic kidney disease characterized by gradual kidney enlargement and progressive renal function loss. Pregnancy is a significant risk factor for adverse maternal and fetal outcomes in chronic kidney disease (CKD), regardless of the nephropathy. Women with ADPKD often face concerns about worsening their renal condition and passing the disease on to their offspring. Recent studies show better outcomes due to improved pregnancy surveillance and prior counseling. Risk factors for poor fetal and maternal outcomes include advanced maternal age, pre-existing hypertension, urinary infections, proteinuria, and renal failure. Collaboration between nephrologists and gynecologists is essential for addressing clinically significant concerns in pregnant women with ADPKD. Nephrologists should play an active role in assisting and supporting pregnant ADPKD patients as part of a multidisciplinary team.

Congenital vertical talus foot is a complex deformity, characterized by a dislocation of the talus-calcanear navicular joint. It is a rare form of congenital flat foot, where the hindfoot is valgus and equine, the midfoot dorsiflexed and the forefoot abducted. Regardless of the type of classification, the therapeutic approach and prognosis must take into account the functionality and motility of the foot. Initial treatment is manipulative. After 3 months of age, it is possible to think about soft tissue surgery. In this study, we present congenital vertical talus feet treated at the Pediatric Orthopedics Department of SS. Antonio Biagio and Cesare Arrigo Children’s Hospital of Alessandria from 1995 to 2022. All 8 patients (12 feet) underwent through the surgical operation technique of open reduction described by Tachdjian and further reviewed and subjected to the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score. The mean follow up is 13 years. Global functional result was good and surgery allowed the growth of the foot, which would otherwise be blocked by an ax that is the vertical talus. Questioned remotely, all patients perform sporting activities and wear normal footwear.

The worst type of hip developmental dysplasia, known as congenital hip dislocation (CHD), is characterized by acetabular cavity, proximal femoral segment, and ligamentus capsule apparatus dysmorphisms that result in partial or total loss of the hip joint’s relationship. We provide the following example: Hip dislocation has been diagnosed in a male infant 2 months old. The patient underwent progressive abduction followed by longitudinal skin traction using the Morel technique. After performing an artrography on the hip while under general anesthesia, which revealed a reducible and stable hip, we continued with spica cast immobilization in a human position. To promote proper joint development, improve standing posture, enhance gait, and correct pelvic and spinal imbalances, the treatment aims to reduce joint dislocation and rebuild joint relationships. To gradually clean the structures and lower the risk of distant avascular necrosis (AVN) of the femoral head development, slow and gradual traction is applied to Morel’s bed.

L’approvazione della legge sulle Unioni Civili (legge 20 maggio 2016 n. 76) ha segnato un passaggio importante in Italia sul versante del cambiamento istituzionale, culturale e del riconoscimento dei diritti delle persone LGBT+ con effetti anche sul versante conoscitivo rendendo possibile indagare, in maniera campionaria o censuaria, un segmento specifico di tale popolazione. Obiettivo del presente lavoro è fornire un quadro delle principali caratteristiche socio-demografiche delle persone in unione civile ed effettuare prime analisi esplorative sull’esistenza di eventuali asimmetrie di coppia considerando il grado di omogamia/eterogamia tra i partner relativamente ad alcuni indicatori di appartenenza a un gruppo (livello di istruzione, condizione occupazionale e posizione professionale, mobilità territoriale e cittadinanza) nonché il grado di apertura ed eterogamia delle coppie omosessuali, di donne e uomini, in confronto alle coppie eterosessuali.

Congenital Clubfoot (CCF) treatment involves a surgical procedure on the Achilles tendon most of the time, i.e. tenotomy or, in selected cases, Z-plasty lengthening. Many authors have studied the outcomes of Achilles tenotomy, describing complete clinical and ultrasound tendon fibers integrity restoration 3-6 weeks after surgery. Nevertheless, little is known about the mechanical properties of the operated tendon. Recently, cases of subcutaneous rupture of the Achilles tendon have been described in adolescents who practiced sports and who had undergone Achilles tenotomy for congenital clubfoot in childhood. Authors report two cases of atraumatic Achilles tendon injury (subcutaneous rupture and intratendinous ossification) in adult patients who had been treated for congenital clubfoot in childhood. In both cases, no causes determining the injury were identified; in the medical history there was a Z-plasty lengthening of the Achilles tendon, performed within the first year of life, which could be considered a predisposing factor. The usefulness of long-term monitoring of patients treated for CCF with surgical procedures on the Achilles tendon is therefore hypothesized, in order to promptly identify by symptoms, clinical pictures and ultrasound criteria, tendon suffering that may predispose subcutaneous rupture.

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In the 19th century, Red kite (Milvus milvus) was very common and widespread in Sardinia, but in the mid-900 an important decline occurred. Since the 1970s the species has been studied more continuously, but in recent years the published data seem contradictory. In 2018-2020, authors carried out specific research to collect data on the population of the Red kite in Sardinia exploring both the historical range of the species and areas where the species was reported in the past. In 2018-2020, we estimated 10-13 breeding pairs in an area of about 3,440 km2 located in the north west of Sardinia. As regard wintering, we estimated 30-40 birds in winters 2018-2019 and 2019-2020, whereas 90-110 birds were counted in winter 2020-2021.

Fowler-Stephens Laparoscopic Orchiopexy (FSLO) permits the mobilization of Intra-Abdominal Testis (IAT) to the scrotal position after spermatic vessel ligation. We reported our experience of FSLO for IAT. The charts of all boys who underwent a FSLO were retrospectively reviewed. Data were analysed for demographic data, procedure, complications and follow-up results. From January 2008 to June 2016, 160 laparoscopies for Non Palpable Testis (NPT) were performed at a mean age of 3,2 years. 61% of patients had a right NPT, while 6% were bilateral. In 64 cases, an IAT was found: 20 were managed by FSLO with a two-stage procedure in 11 patients. There were no differences in hospitalisations; one patient had a prolonged ileus. Follow-up ranged from 1 to 8 years. Of the 20 patients who underwent FSLO, testicular atrophy developed in three; the remaining testes were in the scrotal position, with normal consistency. FSLO was applied in 31% of IAT. The overall success rate of the technique was 85 %. The percentage of atrophy associated after spermatic vessels interruption appears to provide a good chance of testicular survival.

Nel corso dell’ultimo convegno dell’Unione Italiana per il Disegno, svoltosi a Napoli, è stata assegnata La Targa d’Oro dell’Unione Italiana per il Disegno (UID) 2017 ad Anna Sgrosso con lo scopo di premiare il complesso delle attività scientifiche e culturali promosse presso l’Università degli Studi di Napoli Federico II durante una lunga e prestigiosa carriera. Grazie ai suoi studi, svolti sia in ambito architettonico che matematico, Anna Sgrosso ha rivitaliz- zato la Geometria descrittiva, trovando nuovo impulso espressivo e comunicativo nello studio delle radici proiet- tive e nei rapporti che la disciplina instaura con il mondo della figurazione e dell’arte [...]

Critical texts: • Topographies of ghost towns: drawings by Emmanuele Lo Giudice • The essential design • Towards a gaseous body. Three rooms: Torre rossa, Racconto Veneziano, Una finestra azzurra

[Digital persona, Big Data and public sphere. What challenges for the democracy to come]. The datification of the society has opened up unthinkable possibilities to improve the quality of our life, but it also poses new challenges. How to ensure that data is not used to enforce invasive control of our lives? How to avoid that the algorithms decide for us even when we don’t want it? How to defend our freedom from cyber-elites as much powerful as they are obscure? In this article, I will illustrate some of the dimensions underlying the relationship between our self-representations in the form of data and the public sphere in an attempt to illuminate that dark side where democracy risk to be confined.

A 62-year-old man with a history of systemic sclerosis was admitted with diffuse alveolar hemorrhage and acute kidney injury without clinical data suggestive of glomerulonephritis. Laboratory tests showed anemia, leukocytosis with neutrophilia, thrombocytopenia, elevated serum creatinine and metabolic acidosis. Antinuclear antibodies were positive at a titer of 1/640 (speckled, 1/160; nucleolar, 1/320) while rheumatoid factor, anti Scl-70, anti-centromere, anti-neutrophil cytoplasmic antibody and anti-glomerular basement membrane antibodies were negative and serum complement levels were within normal range. During the following days, the patient developed multiple organ failure and, eventually, died. Lupus anticoagulant was revealed positive after the patient’s death, suggesting a catastrophic antiphospholipid syndrome. Clinical data and autopsy were consistent with this diagnosis.

During the last Congress of the Unione Italiana per il Disegno, held in Naples, the 2017 UID Gold Medal was awarded to Anna Sgrosso with the aim of rewarding the complex of scientific and cultural activities promoted at the University of Naples Federico II over a long and prestigious career. Thanks to her studies, both in architectural and mathematical fields, Anna Sgrosso has revitalized Descriptive Geometry, finding new expressive and communicative impulse in the study of its projective roots and in the links that this discipline establishes with the world of figuration and art. In particular, Anna Sgrosso’s proposal to use traditional representation systems (Monge, axonometry, perspective) in an unconventional manner led to an innovative interpretation of architecture –realized or in progress–, in which it is possible to identify structure and geometric genesis of the spaces.

We report our experience with a sutureless technique for laparoscopic inguinal hernia repair in children. Twenty-eight children, 12 girls and 16 boys, aged 3 months to 7 years, underwent sutureless laparoscopic inguinal hernia repair. In girls, we utilized simple cauterization of the internal inguinal ring with a single trocar technique. In boys denudation of the peritoneum was obtained utilizing a three-trocar technique. The peritoneum around the internal inguinal ring was peeled off and detached from the vas and the vessels, and then wrapped around the grasper, resulting in a large area of denudation. No perioperative complications were observed. No recurrences nor testicular damage were noted after a mean follow-up of 18 months (range 6-35 months). The mean operative time was 12 min (range 7-20 min) for girls and 19 min (range 15-30 min) for boys. A 6-year-old girl exhibited a lymphocele. The sutureless technique appears to be easy, safe, and effective, provided that the patients are carefully selected. In boys, special attention needs to be paid to preservation of the vas and the testicular vessels.

In questo contributo sono presentati i risultati dello studio compiuto sulle terme romane di Trebula Balliensis, con particolare attenzione ai manufatti rinvenuti negli ambienti W-D-E nel corso degli scavi eseguiti nel 2009. Il materiale ceramico analizzato appartiene alla sequenza stratigrafica UUSS 4-5, relativa al periodo di abbandono dell'impianto termale. Oltre a vari contenitori d'età tardoantica, simili ad altri ben documentati in Campania, appare di particolare rilievo il ritrovamento di numerosi frammenti di lucerne giudaiche con il simbolo del candelabro. Alla luce di questi e altri reperti, si delinea una nuova proposta d'interpretazione sulle ultime fasi di frequentazione della struttura. Judaic Lamps from the Baths of Trebula Balliensis The purpose of this contribution is the analysis of the Baths of Trebula Balliensis, with a particular focus on the diagnostic artifacts recovered from rooms W-D-E (2009 excavations). The analysed ceramic materials are recorded in the stratigraphic sequence UUSS 4-5, related to the abandonment of the spa-complex. In addition to some late-antique classes, all well documented in the Campania region, the finding of a new kind of lamp with the symbol of the menorah is considered as especially relevant. Furthermore, the present study suggests a different line of interpretation regarding the final stages of the site.

We retrospectively reviewed the results of transscrotal orchidopexy in the surgical management of palpable testis. From January 2014 to June 2017, 130 male children with a total of 140 palpable undescended testes (UDT) underwent transscrotal orchidopexy. The charts were retrospectively reviewed for demographic data, preoperative position and mobility of the testis, patency of the peritoneal vaginal duct (PVD), and post-operative complications. The resting position of the testis and its traction towards the scrotum were assessed before surgery and under anaesthesia. The mean age of the patients was 4.6 years. The position of the testis assessed at surgery was in most cases at the external inguinal ring (62.8%), at the neck of the scrotum (15.7%), in the inguinal canal (12.8%), or in an ectopic position (8,5%). A PVD was found in 66 testes (47.1%). Two surgical cases required an inguinal incision. In each patient, the postoperative course was unremarkable. The testicle at 1-year follow-up was in a scrotal position in 134 cases, but 6 patients required a second surgical intervention for re-ascent of the testis. No testicular atrophy or inguinal hernias were observed. Transscrotal orchidopexy is a simple and effective procedure for the treatment of palpable UDT. The incidence of complications is low and manageable, with rapid postoperative recovery and early resumption of normal activities.

A 4 months and half female child come to our attention for congenital dislocation of the left hip, previously treated in another hospital with abduction bracing, without satisfactory results. After progressive longitudinal bilateral traction, closed reduction under general anesthesia was performed and a spica cast was applied in the so-called human position. The patients remained in the spica cast for 6 weeks and then the plaster cast was renewed in narcosis for another 6 weeks. Once the second cast has been removed left femoral nerve palsy was detected. Orthopaedic treatment was interrupted and in 3 months the nerve completely recovered, while the hip was still stable. We followed the child regularly since then, she is now five years old, she is totally asymptomatic, X-rays shows a residual acetabular dysplasia, with no sign of avascular necrosis.

This position paper critically analyses the process to implement the UNESCO Recommendation on the Historic Urban Landscape (2011), exploring evaluation tools, innovative business / management models and financing tools for the conservation and regeneration of Historic Urban Landscape (HUL), to make it operational in the perspective of a circular economy model of sustainable development for city / territory system regeneration. Through evaluation tools, it is possible to pass from general principles to operational practices; to produce empirical evidence of the economic, social and environmental benefits of HUL integrated conservation and regeneration. The challenge of generating a symbiosis between conservation and transformation issues requires adequate evaluation methods, business, management and financing tools, engaging civil society and local stakeholders, capturing both HUL tangible and intangible values to turn the historic urban landscape into a driver of sustainable growth. The analysis carried out in this paper shows that through the suggested tools it is possible to make operational the UNESCO Recommendations, transforming conflicts into opportunities, producing economic attractiveness and strengthen social awareness and cohesion.