Search

Copyright of Enfances, Familles, Generations is the property of Enfances, Familles, Generations and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article discusses the role of elastin and microfibrils in vascular development and ageing. It informs that elastic fibers composed of elastin and fibrillin-rich microfibrills in the cell walls provide elasticity to blood vessels and smoothen the blood pressure and flow delivered to the heart. Genetic alteration in the elastin and fibrillin leads to severe genetic pathologies of the cardiovascular system.