Rôle de l'élastine et des microfibrilles de la paroi artérielle au cours du développement et du vieillissement : complémentarité ou opposition ?

The article discusses the role of elastin and microfibrils in vascular development and ageing. It informs that elastic fibers composed of elastin and fibrillin-rich microfibrills in the cell walls provide elasticity to blood vessels and smoothen the blood pressure and flow delivered to the heart. Genetic alteration in the elastin and fibrillin leads to severe genetic pathologies of the cardiovascular system.