204 results
Search Results
102. LA POLITIQUE CLIMATIQUE EUROPÉENNE : ENTRE NÉCESSITÉ DE LA VERTU ET VERTU DE LA NÉCESSITÉ.
- Author
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Laurent, Éloi and Le Cacheux, Jacques
- Subjects
GOVERNMENT policy on climate change ,ENVIRONMENTAL policy ,GREENHOUSE gas mitigation ,UNITED Nations Framework Convention on Climate Change (1992). Protocols, etc., 1997 December 11 ,CARBON dioxide mitigation ,CONFERENCES & conventions - Abstract
The article focuses on European climate policies. It discusses the European Union (EU) and its influence as a global ecological leader and its adoption of the paquet climat-energie, or European plan on climate change, in 2009, which includes reducing 20% of greenhouse gases by 2020. It discusses norms and technological standards imposed upon manufacturers wanting to sell their products on the European market and implementations in the European carbon market based on the Kyoto protocol to determine the price of carbon dioxide emitted by industries. Further topics include the European Commission, the 2011 United Nations Climate Change Conference held in Durban, South Africa, and the future of climate policies in Europe.
- Published
- 2011
- Full Text
- View/download PDF
103. Abstracts.
- Subjects
MIDDLE Ages ,HISTORY of environmentalism ,EUROPEAN history - Abstract
Abstracts are presented on topics of history including the cultural and social history of Algeria as a French colony from 1830 to 1880, a comparative history of environmentalism in both France and Russia, and the Medieval history of the Western Mediterranean region in the early fourteenth century.
- Published
- 2011
104. Résumés.
- Subjects
MIDDLE Ages ,HISTORY of environmentalism ,EUROPEAN history - Abstract
Abstracts are presented on topics of history including the cultural and social history of Algeria as a French colony from 1830 to 1880, a comparative history of environmentalism in both France and Russia, and the Medieval history of the Western Mediterranean region in the early fourteenth century.
- Published
- 2011
105. L'économie solidaire: une possibilité de relance de la construction européenne?
- Author
-
DACHEUX, Eric and GOUJON, Daniel
- Subjects
INTERNATIONAL economic relations ,FINANCIAL crises ,UTOPIAS - Abstract
Copyright of ESSACHESS is the property of ESSACHESS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2011
106. UNE THÉORIE DE LA COHÉSION SOCIALE.
- Author
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FORSÉ, Michel and PARODI, Maxime
- Subjects
SOCIAL cohesion ,SOCIAL participation ,EQUALITY ,SOCIAL policy - Abstract
The article presents a reflection on the theme of social cohesion, which encompasses such notions as citizen and social participation, shared values, and the decrease of inequalities and segregation. The analysis of social solidarity by French sociologist and philosopher Émile Durkheim, linked to the ideas of French historian Alexis de Tocqueville on this same theme, is examined. The policies of social cohesion developed in Europe in the 20th century and beginning of the 21th century are mentioned.
- Published
- 2009
- Full Text
- View/download PDF
107. (A)typique et (in)certaine? De la protection sociale des formes d'emploi «non standardisées» en Europe.
- Author
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Buschoff, Karin Schulze and Protsch, Paula
- Subjects
ALTERNATIVE work arrangements ,LABOR market ,SOCIAL security ,PART-time employment ,WORK ,SELF-employment - Abstract
Copyright of Revue Internationale de Securite Sociale is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2008
- Full Text
- View/download PDF
108. Conseils d'administration et réseaux d'administrateurs en Europe.
- Author
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Guieu, Gilles and Meschi, Pierre-Xavier
- Subjects
STAKEHOLDERS ,ORGANIZATION ,SOCIAL networks ,SOCIAL groups ,CORPORATE directors - Abstract
Copyright of Revue Française de Gestion is the property of John Libbey Eurotext Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2008
- Full Text
- View/download PDF
109. Dernières avancées sur les carrefours giratoires.
- Author
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Pellecuer, Luc and St-Jacques, Michèle
- Subjects
ROAD interchanges & intersections ,MODELING (Sculpture) ,PUBLIC opinion ,SOCIAL psychology ,ENGINEERING design ,INDUSTRIAL design ,STRUCTURAL design ,STANDARDIZATION - Abstract
Copyright of Canadian Journal of Civil Engineering is the property of Canadian Science Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2008
- Full Text
- View/download PDF
110. NOTICES BIBLIOGRAPHIQUES.
- Subjects
GLOBALIZATION ,SOCIAL policy ,POLITICAL planning ,SOCIAL security - Abstract
Book reviewed in this articles: Politique sociale, développement et Etat providence Stiglitz, Joseph E. Making globalization work. Vij, Ritu (sous la direction de). Globalization and welfare: A critical reader. Deacon, Bob. Global social policy and governance. Castles, Francis G. (sous la direction de). The disappearing State? Retrenchment realities in an age of globalisation. Carr, Fergus; Massey, Andrew (sous la direction de). Public policy and the new European agendas. Faverel-Dapas, Brigitte; Quintin, Odile. L'Europe sociale. Van Langendonck, Jef (sous la direction de). The right to social security. Riedel, Eibe (sous la direction de). Social security as a human right: Drafting a general comment on Article 9 ICESCR: Some challenges. Fitzpatrick, Pamela; Ripley, Fiona; Singh, Anne. Migration and social security handbook: A rights guide for people entering and leaving the UK. Berkel, Rik van; Valkenburg, Ben. Making it personal: Individualising activation services in the EU. Serrano Pascual, Amparo; Magnusson, Lars (sous la direction de). Reshaping welfare states and activation regimes in Europe. Sinn, Hans-Werner, et al. Redesigning the welfare state: Germany's current agenda for an activating social assistance. Marston, Greg; McDonald, Catherine (sous la direction de). Analysing social policy: A governmental approach. Wallace, Mike; Fertig, Michael; Schneller, Eugene (sous la direction de). Managing change in the public services. Riesco, Manuel (sous la direction de). Latin America: A new developmental welfare state model in the making? Krömmelbein, Silvia; et al. Einstellungen zum Sozialstaat: Repräsentative Querschnittsuntersuchung zu grundsätzlichen gesundheits- und sozialpolitischen Einstellungen in der Bevölkerung. Dobner, Petra. Neue soziale Frage und Sozialpolitik. Travail, revenus, famille, exclusion Spicker, Paul. The idea of poverty. Lang, Kevin. Poverty and discrimination. Marx, Ive. A new social question? On minimum income protection in the post-industrial era. Bischoff, Joachim. Allgemeines Grundeinkommen: Fundament für soziale Sicherheit? Leisering, Lutz; Buhr, Petra; Traiser-Diop, Ute. Soziale Grundsicherung in der Weltgesellschaft: Monetäre Mindestsicherungs-systeme in den Ländern des Südens und des Nordens: Weltweiter Survey und theoretische Verortung. Stähler, Nikolai. Employment protection and unemployment: A theoretical analysis evaluating recent policy proposals. Kemp, Peter A. (sous la direction de). Housing allowances in comparative perspective. Problèmes de l'âge Pension funds investment perspectives. Immergut, Ellen M.; Anderson, Karen M.; Schulze, Isabelle (sous la direction de). The handbook of West European pension politics. Questions de santé Dussault, Gilles; Fournier, Pierre; Letourmy, Alain (sous la direction de). L'assurance maladie en Afrique francophone: améliorer l'accès aux soins et lutter contre la pauvreté. Beau, Pascal. Lettre ouverte au Ministre de la santé. [ABSTRACT FROM AUTHOR]
- Published
- 2007
- Full Text
- View/download PDF
111. Un centre culturel Google: pour quoi faire?
- Subjects
DIGITIZATION of library materials ,DIGITIZATION of museum collections ,COMPUTER network resources - Abstract
The article reports that the American internet giant Google announced the creation of a European cultural institute, in a bid to bring actors from the continent's cultural scene closer, and to foster the digitization of a number of cultural archives.
- Published
- 2011
112. Une différence méthodologique: La sémiotique est la 'théorie générale des systèmes de signification' et non pas la théorie des signes.
- Author
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Voigt, V.
- Subjects
SEMIOTICS ,MEANING (Psychology) ,LINGUISTICS ,ETHNOLOGISTS ,LANGUAGE & languages ,SIGNS & symbols - Published
- 1991
113. STRATÉGIES CLIMATIQUES EN EUROPE ET AU CANADA : UNE INTRODUCTION.
- Author
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Laurent, Éloi
- Subjects
CLIMATE change ,ENVIRONMENTAL policy - Abstract
An introduction is presented in which the author discusses topics presented in several articles of this issue related to climate strategies from a European and Canadian perspective based on the 2011 United Nations Climate Change Conference held in Durban, South Africa.
- Published
- 2011
- Full Text
- View/download PDF
114. [France and its African migrants].
- Author
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Courade G
- Subjects
- Africa, Africa South of the Sahara, Africa, Southern, Demography, Developed Countries, Developing Countries, Europe, France, Population, Population Dynamics, Social Change, South Africa, Transients and Migrants, Acculturation, Emigration and Immigration, Politics, Public Policy
- Published
- 1997
115. [Documented foreign immigrants in Italy: ethnic ties and insertion into the labor force].
- Author
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Ambrosini M
- Subjects
- Culture, Demography, Developed Countries, Economics, Europe, Health Workforce, Italy, Population, Population Characteristics, Population Dynamics, Social Change, Acculturation, Emigration and Immigration, Employment, Ethnicity, Occupations, Transients and Migrants
- Published
- 1997
116. [Crisis and demographic transition in Africa].
- Author
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Coussy J and Vallin J
- Subjects
- Africa, Africa South of the Sahara, Demography, Developed Countries, Developing Countries, Europe, France, Economics, Population, Population Dynamics, Public Policy
- Published
- 1996
117. Acces en Conversationnel au Fichier World Transindex. [Online Access to the World Transindex File].
- Author
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Royal Inst. of Tech., Stockholm (Sweden). Library., Pelissier, Denise, and Mallet, Monorama
- Abstract
A database providing bibliographic information and the source for translations of scientific and technical literature from Eastern Europe and Asia into western languages, World Transindex includes the information which was published until 1977 in the World Index of Scientific Translations, Transatom Bulletin, and Bulletin of Translations. It was established in January 1978 using the PASCAL system of the Centre National de la Recherche Scientifique (CNRS), which permits the publication of indexes by photocomposition as well as online searching. Since 1975, the Center of Scientific and Technical Documentation of CNRS has had online access to its own file of translations; in 1978, searching was extended to the World Transindex file. Other available translations prior to 1974 are available through SELECTO. Currently under study are the provision of selective dissemination of information (SDI) services based on profiles of interests, and, eventually, languages, e.g., chemistry in English or French, and the establishment of World Transindex in the Information Retrieval Service (IRS) of the European Space Agency (ASE). This paper provides brief descriptions of the database, online searching procedures, and studies on the use of CRISTAL for information retrieval and the relocation of World Transindex to IRS/ASE. (BBM)
- Published
- 1979
118. [Selective embryonic or fetal reduction by surgical transvaginal ultrasonography].
- Author
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Delafontaine D, Mugniot-bellamy S, Simeon S, and Menard MN
- Subjects
- Biology, Developed Countries, Europe, France, General Surgery, Pregnancy, Reproduction, Embryo, Mammalian, Embryo, Nonmammalian, Obstetric Surgical Procedures, Pregnancy Outcome, Pregnancy, Multiple, Risk Factors, Therapeutics
- Published
- 1991
119. [Migration].
- Author
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Maccotta W, Perotti A, Thebaut F, Cristofanelli L, Pittau F, Sergi N, Pittau L, Morelli A, Morsella M, and Grinover AP
- Subjects
- Americas, Canada, Demography, Economics, Europe, North America, Population, Population Dynamics, Developed Countries, Emigration and Immigration, Social Problems, Socioeconomic Factors
- Published
- 1990
120. The Transformation of Labour Law in Europe : A Comparative Study of 15 Countries, 1945-2004.
- Author
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Verge, Pierre
- Subjects
LABOR laws ,NONFICTION - Abstract
The article reviews the book "The Transformation of Labour Law in Europe: A Comparative Study of 15 Countries, 1945-2004," edited by Bob Hepple and Bruno Veneziani.
- Published
- 2010
- Full Text
- View/download PDF
121. Le francais a l'est de l'Europe (French in Eastern Europe).
- Author
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Ploquin, Francoise
- Abstract
The popularity of French second language instruction, the rebirth of bilingual education, and efforts to establish links with French industry locating in Eastern Europe offer an example to France. It is clear that Eastern Europe views bilingualism as a means of revitalizing the region's role in the European community. (MSE)
- Published
- 1991
122. Jarnvagsdokumentation.
- Subjects
DOCUMENTATION ,RAILROADS ,CLASSIFICATION ,ORGANIZATION ,PUBLICATIONS - Abstract
Presents an abstract of the article 'Jarnvagsdokumentation,' by Britt Johan, published in the journal "Tidskrift for Dokumentation." Description of the organization for railroad documentation in Europe; Publication of a monthly bulletin of documentation with the collaboration of the French, Belgian, Swiss, and Italians; Comparison with railroad documentation in the U.S.
- Published
- 1955
123. [Migrants' remittances and their use].
- Author
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Lebon A
- Subjects
- Demography, Developed Countries, Europe, Population, Population Dynamics, Economics, Emigration and Immigration, Transients and Migrants
- Published
- 1984
- Full Text
- View/download PDF
124. [The narrow path].
- Author
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Duprez D, Benmoura D, Pasturel F, and Isnard-penverne R
- Subjects
- Adolescent, Developed Countries, Europe, Family Planning Services, France, Abortion, Induced, Evaluation Studies as Topic
- Published
- 1979
125. [The large cities of the West in 1300: a critical note on historical demography].
- Author
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Baerten J
- Subjects
- Belgium, Developed Countries, Europe, Geography, Population, Population Characteristics, Research, Social Sciences, Demography, Evaluation Studies as Topic, Urban Population, Urbanization
- Published
- 1980
126. [Italian immigration to France].
- Author
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Wihtol De Wenden C and Palidda S
- Subjects
- Demography, Developed Countries, Europe, France, Italy, Population, Population Dynamics, Education, Emigration and Immigration, Geography, Teaching, Transients and Migrants
- Published
- 1985
127. [Trends in the sex ratio at birth in selected Western countries].
- Author
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Schtickzelle M
- Subjects
- Australia, Biology, Canada, Culture, Europe, Family Characteristics, Family Relations, Latin America, Population, Sex Distribution, Sex Factors, Social Sciences, United States, Age Factors, Birth Order, Demography, Developed Countries, Ethnicity, Politics, Population Characteristics, Sex Ratio
- Published
- 1981
128. [Recent developments in intra-European migration since 1974].
- Author
-
Lebon A and Falchi G
- Subjects
- Demography, Developed Countries, Europe, Population, Population Dynamics, Emigration and Immigration
- Published
- 1980
129. [Fertility Trends in Belgium 1950-1980].
- Author
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Willems P, Wijewickrema S, and Lesthaeghe R
- Subjects
- Age Distribution, Belgium, Birth Intervals, Demography, Developed Countries, Europe, Forecasting, Marital Status, Parity, Population, Population Characteristics, Population Dynamics, Research, Statistics as Topic, Age Factors, Birth Rate, Cohort Studies, Fertility, Marriage
- Published
- 1981
130. PROCÉDÉS CONTRACTUELS ENTRE PARTENAIRES PUBLICS ET PRIVÉS DANS LE DOMAINE DE L'EAU.
- Author
-
Massot, Jean
- Subjects
PUBLIC contracts ,BUSINESS partnerships ,CIVIL service - Abstract
Copyright of Collected Papers of the Faculty of Law in Split / Zbornik Radova Pravnog Fakulteta u Splitu is the property of Split Faculty of Law and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2011
131. LE DROIT DES CONTRATS ET L' APROCHE COMMUNAUTAIRE.
- Author
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Dewost, J. L.
- Subjects
PUBLIC contracts ,EUROPEAN Union law ,GOVERNMENT purchasing ,ECONOMIC competition - Abstract
Copyright of Collected Papers of the Faculty of Law in Split / Zbornik Radova Pravnog Fakulteta u Splitu is the property of Split Faculty of Law and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2011
132. Quand les étudiants jugent leurs études. Quelques enseignements d'une recherche internationale.
- Author
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Lima, Laurent and Hadji, Charles
- Subjects
STUDENT evaluation of curriculum ,TEACHING ,CURRICULUM evaluation ,ACTIVITY programs in education ,LEARNING ,TEACHERS ,RESEARCH teams ,HIGHER education ,CURRICULUM - Abstract
Copyright of Papers: Revista de Sociologia is the property of Universitat Autonoma de Barcelona and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2005
133. [Use of synthetic substances in France and in Europe].
- Author
-
Debruyne D, Monzon E, Perino J, Haramburu F, Daveluy A, Lazès-Charmetant A, and Giraudon I
- Subjects
- Europe, France epidemiology, Humans, Psychotropic Drugs adverse effects, Alkaloids, Illicit Drugs, Substance-Related Disorders epidemiology
- Abstract
This paper aims to present the main information presented at the 9th Meeting about addictovigilance in 2016 by four healthcare professionals and addiction experts on the issue of new psychoactive substance use. A new psychoactive substance (NPS) is defined as a narcotic or psychotropic drug, in pure form or in preparation, that is not controlled by the United Nations drug conventions, but which may pose a public health threat comparable to that posed by substances listed in these conventions. The emergence of NPS consumption is a worldwide concern. Although NPS are less consumed than established drugs, there has been a sharp increase in their use over the last few years, notably of synthetic cathinones, synthetic cannabinoids and, more recently, synthetic opioids. The latter in particular are involved in deaths in Europe. However, "established" drugs (MDMA [methylenedioxymethamphetamine], amphetamines, LSD, methamphetamine) are far from being dethroned by the more recent substances: they are considered "a safe bet" already "tried and tested" by many consumers over the years. MDMA, in particular, also known as ecstasy, which has been used as a recreational drug since the 1990s, saw its consumption decrease until 2010, and then increase again, especially in higher amounts; inexpensive and easily accessible, it is increasingly associated with emergency admissions or deaths in France. The perpetual appearance of new substances on the drug market is obligating to improve knowledge on these products, particularly by focusing on their analytical identification, and also by monitoring their use and harms., (Copyright © 2020 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
134. The role of biosimilar granulocyte colony stimulating factor (GCSF) Zarzio for progenitor cell mobilization and the treatment of therapy-induced neutropenia in adult hematopoietic stem cell transplantation.
- Author
-
Severson CC
- Subjects
- Adult, Aged, Aged, 80 and over, Biosimilar Pharmaceuticals economics, Canada, Europe, Female, Filgrastim economics, Humans, Male, Middle Aged, Stem Cells physiology, United States, Young Adult, Biosimilar Pharmaceuticals therapeutic use, Clinical Trials as Topic, Filgrastim therapeutic use, Hematopoietic Stem Cell Transplantation adverse effects, Neutropenia drug therapy, Neutropenia etiology, Stem Cells drug effects
- Abstract
Originator GCSF (Neupogen) has been used to mobilize progenitor stem cells and treat therapy-induced neutropenia in Canadian stem cell transplant settings for years. Although its benefit is not in question, viable alternatives are available. Biosimilar GCSF (Zarzio) is widely in use in Europe since 2009 and was recently approved in the U.S.for the same five indications as Neupogen. Zarzio is reported as safe, equally efficacious, more accessible and cost effective without negatively impacting patient outcomes. This paper summarizes the supporting evidence.
- Published
- 2015
135. [EUTHANASIA AND ASSISTED SUICIDE].
- Author
-
Lantero C
- Subjects
- Europe, France, Humans, Terminology as Topic, Euthanasia legislation & jurisprudence, Suicide, Assisted legislation & jurisprudence
- Abstract
Euthanasia and assisted suicide are not part of French laws of bioethics and lack, for the time being, definition and normative framework other than their criminal prosecution. To transform them into a right, these concepts certainly call for an ethical and legal debate. This paper aims to question the ideas to be considered, the conceptual bases and normative tools that may be useful to the discussion.
- Published
- 2015
136. [Therapeutic management of bipolar disorder in France and Europe: a multinational longitudinal study (WAVE-bd)].
- Author
-
Bellivier F, Delavest M, Coulomb S, Figueira ML, Langosch JM, Souery D, and Vieta E
- Subjects
- Adult, Bipolar Disorder diagnosis, Bipolar Disorder psychology, Drug Utilization statistics & numerical data, Europe, Female, France, Guideline Adherence, Humans, Longitudinal Studies, Male, Middle Aged, Bipolar Disorder drug therapy, Cross-Cultural Comparison, Psychotropic Drugs therapeutic use
- Abstract
Background: Bipolar disorder is a complex disease which requires multiple healthcare resources and complex medical care programs including pharmacological and non pharmacological treatment. If mood stabilizers remain the corner stone for bipolar disorder treatment, the development of atypical antipsychotics and their use as mood stabilizers has significantly modified therapeutic care. At the present time, psychiatrists have a large variety of psychotropic drugs for bipolar disorder: mood stabilizers, atypical antipsychotics, antidepressants, anxiolytics… However, despite the publication of guidelines on pharmacological treatment, with a high degree of consensus, everyday clinical practices remain heterogeneous. Moreover, there are few longitudinal studies to describe therapeutic management of bipolar disorder, whatever the phase of the disease is. Indeed, most of the studies are carried out on a specific phase of the disease or treatment. And there is no study comparing French and European practices., Objectives: In this paper, we aim to present the comparison of the management of pharmacological treatments of bipolar disorder between France and Europe, using the data of the observational Wide AmbispectiVE study of the clinical management and burden of bipolar disorder (WAVE-bd study)., Methods: The WAVE-bd study is a multinational, multicentre and non-interventional cohort study of patients diagnosed with BD type I or type II, according to DSM IV-TR criteria, in any phase of the disorder, who have experienced at least one mood event during the 12 months before enrolment. In total, 2507 patients have been included across 8 countries of Europe (480 in France). Data collection was retrospective (from 3 to 12 months), but also prospective (from 9 to 15 months) for a total study length of 12 to 27 months. Main outcome measures were the healthcare resource use and pharmacological treatments., Results: Our results show differences in the therapeutic management of bipolar disorder between France and other European countries. Regarding healthcare resource use, our results show that French patients consult more frequently a psychiatrist or a psychologist and less frequently a general practitioner or the emergency ward in comparison with patients from other European countries. In the whole European population, including France, atypical antipsychotics are widely used. Only 25% of the patients receive lithium and more than 50% of the patients receive antidepressants, while their use in bipolar disorder remains controversial. Most of the patients receive polymedication. Considering all phases of the disease pooled, less lithium and less atypical antipsychotics are prescribed to French patients, whereas they receive more antidepressants and more benzodiazepines than patients from other European countries. On the over hand, prescription of anticonvulsants and electroconvulsive therapy are equal. Moreover, data analyses by polarity of the episodes globally confirm these trends. There are a few exceptions: mixed states, in which lithium is twice more prescribed in France in comparison to other countries; depressive states, in which antidepressants are even more prescribed in other countries than in France; and less prescription of anticonvulsants in manic, mixed and euthymic phases in France., Conclusion: The WAVE-bd study is the first observational study conducted on a large sample of bipolar I and II patients that compares therapeutic management between France and other European countries. The differences observed in therapeutic care across the different phases of the disease show that treatments differ depending on the countries studied, but also according to the preventive or curative phases, polarity of the bipolar disorder, comorbidities, impact of guidelines, and care organization. Although French patients have been treated by less lithium and less atypical antipsychotics than other European patients, they receive more antidepressants and more benzodiazepines. Finally, patients generally receive polymedication and the diversity in prescriptions shows how bipolar disorder is a complex disorder., (Copyright © 2014 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF
137. [Major milestones for European pharmaceutical policy].
- Author
-
Sauer F
- Subjects
- Europe, History, 20th Century, History, 21st Century, Government Agencies history, Legislation, Drug history
- Abstract
Under the 1985 White Paper on the completion of the single market, several pharmaceutical harmonisation measures were unanimously adopted, in favor of biotech products and on pricing transparency, legal status of prescription, wholesale distribution and advertising. The European pharmaceutical harmonisation was extended to Norway and Iceland, to new accession member states and through major international conferences with the US and Japan (ICH). Starting in 1995, the European medicines agency has produced an efficient marketing authorisation system for new human and veterinary medicines. The system was extended to pediatric medicines and advanced therapies. The monitoring of drug adverse effects (pharmacovigilance) has been gradually strengthened.
- Published
- 2014
138. [Cancer diagnosis during pregnancy: importance of a national and European registration].
- Author
-
Gziri MM, Goffin F, Debieve F, and Amant F
- Subjects
- Adult, Antineoplastic Agents administration & dosage, Belgium, Cooperative Behavior, Europe, Female, Follow-Up Studies, Humans, Incidence, Infant, Newborn, Middle Aged, Pregnancy, Pregnancy Complications, Neoplastic epidemiology, Pregnancy Complications, Neoplastic pathology, Young Adult, Antineoplastic Agents therapeutic use, Pregnancy Complications, Neoplastic therapy, Registries
- Abstract
Cancer during pregnancy is relatively rare, but its incidence has been increasing over recent years. A European study has been launched in 2005 by F. Amant (KUL) to register all pregnant patients with a cancer diagnosis with or without treatment during pregnancy (surgery, chemotherapy and/or radiotherapy). All infants exposed to chemotherapy and/or radiotherapy are also followed up by pediatricians, neurologists, cardiologists and psychologists. In Belgium, French- and Dutch- language hospitals are working in close collaboration to follow these pregnant patients. The national results are summarized in this paper.
- Published
- 2013
139. [Detection of processed animal protein: European experience and perspectives].
- Author
-
Plouvier BM, Baeten V, Maudoux JP, Vanopdenbosch E, Berkvens D, Degand G, and Saegerman C
- Subjects
- Animal Feed analysis, Animals, Chromatography veterinary, Europe, Food Handling standards, Immunologic Techniques veterinary, Microscopy methods, Microscopy standards, Microscopy veterinary, Polymerase Chain Reaction veterinary, Sensitivity and Specificity, Specimen Handling standards, Specimen Handling veterinary, Spectroscopy, Near-Infrared veterinary, Animal Feed standards, Dietary Proteins analysis, Prion Diseases prevention & control
- Abstract
European Commission Regulation (EC) No. 152/2009 imposes optical microscopy as the reference method for official controls to detect traces of animal protein in animal feed. Since 1 July 2004, the one-solvent technique has been the only authorised variant of optical microscopy. Its detection limit is 0.1% of meat-and-bone meal. Other techniques--using molecular biology (polymerase chain reaction, immunology), microscopy or near-infrared imaging--have been developed in the past ten years to supplement the official method, which has certain limitations. This paper compares and discusses the different techniques, highlighting the strengths of each technique in order to propose a feasible control scheme to improve the sensitivity and specificity of the technique for the detection of processed animal protein in livestock feed.
- Published
- 2012
140. [New European guidelines for the management of dyslipidaemia in cardiovascular prevention].
- Author
-
Descamps OS, De Backer G, Annemans L, Muls E, and Scheen AJ
- Subjects
- Algorithms, Belgium, Cardiovascular Diseases etiology, Cardiovascular Diseases mortality, Cholesterol blood, Cholesterol, LDL analysis, Cholesterol, LDL blood, Dyslipidemias blood, Dyslipidemias complications, Dyslipidemias mortality, Europe, Female, Humans, Hypolipidemic Agents therapeutic use, Male, Reference Values, Research Design, Risk Factors, Sex Factors, Smoking adverse effects, Smoking blood, Cardiovascular Diseases prevention & control, Dyslipidemias therapy, Practice Guidelines as Topic
- Abstract
The new guidelines from the European Atherosclerosis Society and the European Society of Cardiology include a number of updated items. In this paper, we summarize 4 of these changes that we consider to be the most pertinent. Firstly, cardiovascular risk is now stratified according to 4 (previously 2) categories: "very high risk" (patients with cardiovascular disease, patients with diabetes > 40 years old who have at least one other risk factor, patients with kidney failure, or patients in primary prevention with a SCORE value > or = 10%); "high risk" (patients in primary prevention with a SCORE value > or = 5% and < 10% or patients with a particularly serious risk factor such as familial hypercholesterolaemia or patients with diabetes < 40 years old without any other risk factor); "moderate risk" (primary prevention with SCORE > or = 1% and < 5%); and "low risk" (primary prevention with SCORE < 1%). The SCORE value for patients in primary prevention is estimated using the SCORE table (calibrated for Belgium). Risk in this table may now be corrected according to HDL cholesterol level. Secondly, the therapeutic targets for each category are now more stringent: LDL cholesterol < 70 mg/dl (or reduced by at least 50%) if the risk is "very high"; < 100 mg/dl if the risk is "high"; and < 115 mg/dl if the risk is "moderate". Thirdly, for patients at "high" or "very high" risk, particularly in patients with combined dyslipidaemia, two further therapeutic targets should be considered: non-HDL cholesterol and apolipoprotein B levels. Fourthly, the follow-up of efficacy (lipid profile) and tolerance (hepatic and muscular enzymes) is described in more details so as to harmonize case management in clinical practice.
- Published
- 2012
141. [Practice guidelines of the European Society of Hypertension for home blood pressure measurement].
- Author
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Frantz J, Feihl F, and Waeber B
- Subjects
- Europe, Humans, Blood Pressure Monitoring, Ambulatory standards
- Abstract
Self-measurement of blood pressure at home is increasingly used in the diagnostic and therapeutic approach of hypertension. This technique allows multiple measurements of blood pressure away from the clinical setting, making it possible to improve the evaluation of cardiovascular risk. Recently new guidelines on the use of self-measured blood pressure have been made available by the European Society of Hypertension, as summarized in the present paper.
- Published
- 2010
142. [Teenagers' suicides and suicide attempts: finding one's way in epidemiologic data].
- Author
-
de Tournemire R
- Subjects
- Adolescent, Communications Media statistics & numerical data, Criminal Law legislation & jurisprudence, Epidemiologic Factors, Europe epidemiology, France epidemiology, Humans, Psychology, Adolescent, Suicide statistics & numerical data, Suicide, Attempted statistics & numerical data
- Abstract
This paper engages into a global assessment of statistics and their potential uses, ranging from 19th century accounts of "suicidal acts" by the central services of criminal justice in France, to European comparative data on suicide in the years 2000. The most recent facts and figures about teenagers' suicides in France are taken into account, thanks to the Inserm records on deaths by suicide and to public polls on suicidal attempts., (Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.)
- Published
- 2010
- Full Text
- View/download PDF
143. [Psychotic states in young migrants and children of migrants].
- Author
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Baubet T, Taïeb O, Guillaume J, and Moro MR
- Subjects
- Adolescent, Adult, Child, Cross-Cultural Comparison, Cross-Sectional Studies, Europe, Health Surveys, Humans, Life Change Events, Psychotic Disorders diagnosis, Risk Factors, United States, Young Adult, Emigrants and Immigrants psychology, Emigrants and Immigrants statistics & numerical data, Psychotic Disorders epidemiology, Psychotic Disorders ethnology, Refugees psychology, Refugees statistics & numerical data
- Abstract
Psychiatric literature documenting increased rates of psychotic illness among migrants in European countries has been more and more reported during the past two decades. Social causes to this phenomenon have been highlighted. In this paper, we review and discuss this literature from the cultural psychiatry perspective. We can point three limitations to these works : the definition of the studied groups, the cultural validity diagnoses, and the psychic impact of migration and its complexity not being considered enough. The above considerations lead us to go forward with studies addressing this question. The need to construct methodologies addressing psychiatric epidemiology, transcultural psychiatry and human sciences is underlined.
- Published
- 2009
- Full Text
- View/download PDF
144. [GA2LEN (Global Allergy and Asthma European Network)].
- Author
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Bousquet J, Kauffmann F, Demoly P, Leynaert B, Bousquet PJ, Demenais F, Lenzen G, Burney PG, Zuberbier T, and Van Cauwenberge P
- Subjects
- Allergy and Immunology, Europe, Humans, Asthma, Hypersensitivity, International Cooperation, Research
- Abstract
Allergic diseases represent a major health problem in Europe. They are increasing in prevalence, severity and costs. GA2LEN (Global Allergy and Asthma European Network), an FP6 Network of Excellence, was created in 2005 as a vehicle to ensure excellence in research bringing together research and clinical institutions to combat fragmentation in the European research area and to tackle Allergy in its globality. GA2LEN benefited greatly from the voluntary efforts of researchers who are strongly committed to this model of pan-European collaboration. The network was organized in order to increase networking for scientific projects in allergy and asthma around Europe and to make GA2LEN the world leader in the field. Besides these activities, research has been jointly made and the first papers are being published. GA2LEN achievements in general can be grouped as those for a durable infrastructure built up during the project phase those which are project-related work based on these novel infrastructures, and the development and implementations of guidelines. The major achievements of GA2LEN are reported in this paper.
- Published
- 2009
- Full Text
- View/download PDF
145. [The black death in Christian and Muslim Occident, 1347-1353].
- Author
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Barry S and Gualde N
- Subjects
- Asia epidemiology, Europe epidemiology, History, Medieval, Humans, Plague epidemiology, Plague transmission, Disease Outbreaks history, Plague history
- Abstract
Between the years 1346 and 1353, a terrible epidemic swept over Western Asia, the Middle East, Africa, and Europe, causing catastrophic losses of population everywhere, both in the rural areas and in towns and cities. The Black Death was a disease of such magnitude that it not only shook the Old World to its economic and social foundations but changed the course of human history. The authors considered and analyzed many studies on the Black Death published in different languages. In the present paper they report medical and epidemiological specificities of the pandemic as well as its geographical origins and the routes of its spread.
- Published
- 2008
- Full Text
- View/download PDF
146. [Traditional and translational medicine].
- Author
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Godfraind T
- Subjects
- Drug Evaluation trends, Europe, History, 19th Century, History, 20th Century, History, Ancient, Humans, Molecular Biology, Pharmacology, Clinical history, Proteomics, Therapies, Investigational, United States, Biomarkers, Chemistry, Pharmaceutical methods, Medicine, Traditional history, Pharmacogenetics, Technology, Pharmaceutical, Toxicology methods
- Abstract
In the second half of the 20th century, the development of experimental pharmacology led to the discovery of powerful new therapeutic agents, but production has since faltered, particularly in Europe. The purpose of this paper is to review how the gap in the production of novel medicines between Europe and the USA could be filled by proper use of molecular biology data. The European program entitled 'The Innovative Medicines Initiative' could facilitate the translation of information from benchtop to bedside.
- Published
- 2007
147. [Iron therapy: is it different with peritoneal dialysis compared to haemodialysis?].
- Author
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Durand PY
- Subjects
- Anemia, Iron-Deficiency etiology, Erythropoietin therapeutic use, Europe, France, Humans, Kidney Failure, Chronic complications, Kidney Function Tests, United States, Anemia, Iron-Deficiency therapy, Iron therapeutic use, Peritoneal Dialysis, Renal Dialysis
- Abstract
This paper reviews literature data on iron replacement (loading) for peritoneal dialysis patients. The 3 main sources of clinical guidelines (American NKF-K/DOQI, European EBPG and French AFSSAPS) agree about the definition of iron deficience, but are not similar about the haemoglobin/hematocrit targets for EPO treatment, and for the route of iron administration (oral versus intravenous). Iron requirements are less in PD HD patients. That could be explained by several factors: less blood losses, preservation of a residual renal function, better digestive iron absorption due to a greater hepcidin excretion. Intravenous route for iron sucrose is more efficient than oral route. Taking into account the iron requirements for PD patients, monthly 200 mg iron sucrose infusions over 5 mn seem to be safe and sufficient for most patients.
- Published
- 2006
148. [What's new in geriatric oncology?].
- Author
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Terret C, Albrand G, Jeanton M, Courpron P, and Droz JP
- Subjects
- Aged, Europe epidemiology, Humans, Incidence, Life Expectancy, Neoplasms pathology, Patient Care Planning, Patient Care Team, Quality of Life, Geriatrics trends, Medical Oncology trends, Neoplasms therapy
- Abstract
Remarkably, although 60% of new cancer cases and over 70% of cancer deaths occur in patients aged 65 years and older in Europe, standard treatment strategies have been mostly validated in younger adults. This demographic trend has led to the emergence of a new medical discipline, geriatric oncology and the development worldwide of geriatric oncology programs for the individualized management of elderly cancer patients. Elderly cancer patients represent an increasing share of the population and strategies for treating cancer must evolve to face this ineluctable reality. Treatment should take into account the highly heterogeneous physiological age of the elderly, their individual life expectancy, functional reserves, social support and preferences. French geriatric oncology programs have been mostly based on the interdependence of geriatricians, oncologists and auxiliary nursing people. This approach represent the best way to offer patients optimal management; oncologists and geriatricians collaborate to assess both global health status by means of Comprehensive Geriatric Assessment (CGA) and tumor stage by means of Comprehensive Tumor Assessment (CTA) and to initiate individualized care plans, involving comprehensive management and follow-up of all identified problems. This paper focuses on progress observed in the field of geriatric oncology both in France and worldwide.
- Published
- 2006
149. [Familial violence during pregnancy].
- Author
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Saurel-Cubizolles MJ and Lelong N
- Subjects
- Adolescent, Adult, Data Collection, Europe, Female, Humans, Pregnancy, Spouse Abuse statistics & numerical data
- Abstract
After a review of medical literature on domestic violence during pregnancy, this paper shows the results of a survey carried out in 16 European countries. The percentage of women reporting domestic violence during pregnancy varies with the country; it is specially high in Russia, Poland and Czech Republic. Women who live without partner, those whose the couple has been separated during the pregnancy or those living in an overcrowded house have been more often victim of domestic violence. Domestic violence is significantly related to preterm birth risk.
- Published
- 2005
- Full Text
- View/download PDF
150. [Gender gap in life expectancy: the reasons for a reduction of female advantage].
- Author
-
Meslé F
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Europe epidemiology, Female, France epidemiology, Humans, Infant, Japan epidemiology, Male, Middle Aged, Mortality trends, Sex Distribution, Sex Factors, Life Expectancy trends
- Abstract
Background: After a large increase during the 19th and the 20th century, for two decades the gap in life expectancy between sexes has been reducing in most industrialised countries. In France, where it was specially large, it stopped increasing in the early 1980s and decreased in the most recent years. The paper investigates reasons for these recent trends in France and in the industrialised countries., Methods: Two types of data are used for analysis. Death probabilities from life tables are used for calculating male excess mortality by age and estimating the role of various age groups in life expectancy differences by sex. Sex- and cause-specific mortality rates from INED database for France and from WHO database for other countries are used to assess the part played by various causes of death in the gender gap and its evolution., Results: In France, the stabilisation of the gap is mainly related to the decrease in cardiovascular mortality for men who benefit from the same progress but later than women. In the most recent years, the reduction of the gap is due to the trend reversal of male cancer mortality which is now decreasing, specially because of the reduction of lung cancer mortality. In European countries, taken as examples (England & Wales, Sweden, Switzerland, Italy) cardiovascular mortality is also the main responsible for the decreasing differences. Conversely, in Japan, the gap is still increasing specially for mortality from cancer and respiratory diseases., Conclusions: The recent gap narrowing between male and female life expectancy in France is not a specific case. It does not mean that female health situation is worsening but it is related to an acceleration of progress for males. This reduction will most probably go on in the next years, except if females would enjoy dramatic progression in old age mortality.
- Published
- 2004
- Full Text
- View/download PDF
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