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Background: Respiratory-triggered (RT) and breath-hold are the most common acquisition modalities for magnetic resonance cholangiopancreatography (MRCP). The present study compared the three different acquisition modalities for optimizing the use of MRCP in patients with diseases of the pancreatic and biliary systems. Materials and methods: Three MRCP acquisition modalities were used in this study: conventional respiratory-triggered sampling perfection with application-optimized contrasts using different flip evolutions (RT-SPACE), modified RT-SPACE, and breath-hold (BH)-SPACE. Fifty-eight patients with clinically suspected pancreatic and biliary system disease were included. All image data were acquired on a 1.5 T MR. Scan time and image quality were compared between the three acquisition modalities. Friedman test, which was followed by post-hoc analysis, was performed among triple-scan protocol. Results: There was a significant difference in the mean acquisition time among conventional RT-SPACE, modified RT-SPACE, and BH-SPACE (167.41±32.11 seconds vs 50.84±73.78 seconds vs 18.00 seconds, P 0.05) among the 3 groups regarding quality of overall image, image clarity, background inhibition, and visualization of the pancreatic and biliary system. Conclusions: MRCP acquisition with the modified RT-SPACE sequence greatly shortens the acquisition time with comparable quality images. The MRCP acquisition modality could be designed based on the patient's situation to improve the examination pass rate and obtain excellent images for diagnosis.

Abstract Background Tumor budding (TB) is a negative prognostic factor in colorectal cancer; however, its prognostic impact following neoadjuvant therapy for patients with rectal cancer remains unclear. This study aims to assess the prognostic impact of TB and the correlation between TB and other pathological features in patients with rectal cancer after neoadjuvant therapy. Methods A comprehensive search of PubMed, Embase, Cochrane, Scopus, CNKI, Wanfang, and ClinicalKey databases was conducted for studies on the prognosis of TB in rectal cancer after neoadjuvant therapy from the inception of the databases to January 2023, and the final literature included was determined using predefined criteria. Quality assessment of the studies included, extraction of general and prognostic information from them, and meta-analyses were carried out progressively. Results A total of 11 studies were included, and the results of the meta-analysis showed that high-grade tumor budding (TB-1) increased the risk of poor 5-year disease-free survival (HR = 1.75, 95% CI 1.38–2.22, P

Abstract Objective At present, pancreatic cancer (PC) has a high morbidity and mortality rate and a poor prognosis. The aim of this article was to study the efficacy and safety of apatinib combined with radiotherapy in the treatment of advanced PC. Methods The PubMed, Cochrane Library, Embase, Wanfang, CNKI, VIP, and CBM databases were searched by computer to identify studies on the application of apatinib in patients with advanced PC. The patients in the included study were divided into an observation group (apatinib combined with radiotherapy) and a control group (radiotherapy only), and meta-analysis was performed for each outcome with Revman 5.4 software. This study was successfully registered on the PROSPERO website, and the registration number is CRD: 42,022,384,056 (available at https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=384056 ). Results A total of 7 randomized controlled trials (RCTs) with 428 patients were included, including 215 in the observation group and 213 in the control group. Compared with the control group, the observation group showed a greater objective response rate [OR = 3.26, 95% CI (2.18, 4.87), P

Abstract Recent experiments on sound waves in a unitary Fermi gas reveal many transport properties about strongly interacting fermions. Sound propagates through the coupling of momentum and heat transport, and attenuates strongly with the presence of a phase transition. In this work, focusing on the temperature regimes near and below the superfluid critical temperature $$T_c$$ T c in the BCS-BEC crossover, we present a Kubo-based microscopic calculation of thermal conductivity $$\kappa$$ κ , which has not attracted much attention compared to the shear viscosity. Our approach primarily addresses the contributions of the fermionic quasiparticles to thermal transport and our results return to the kinetic descriptions at high temperatures. $$\kappa$$ κ drops upon crossing the pseudogap temperature $$T^*$$ T ∗ , and its temperature dependence changes below $$T_c$$ T c . The drops become more pronounced on the weakly coupled BCS side, where the Pauli blocking causes the upturn of $$\kappa$$ κ above $$T^*$$ T ∗ . Our calculations fit well with the sound measurement on the damping rate.

The k-nearest neighborhoods (kNN) of feature points of complex surface model are usually isotropic, which may lead to sharp feature blurring during data processing, such as noise removal and surface reconstruction. To address this issue, a new method was proposed to search the anisotropic neighborhood for point cloud with sharp feature. Constructing KD tree and calculating kNN for point cloud data, the principal component analysis method was employed to detect feature points and estimate normal vectors of points. Moreover, improved bilateral normal filter was used to refine the normal vector of feature point to obtain more accurate normal vector. The isotropic kNN of feature point were segmented by mapping the kNN into Gaussian sphere to form different data-clusters, with the hierarchical clustering method used to separate the data in Gaussian sphere into different clusters. The optimal anisotropic neighborhoods of feature point corresponded to the cluster data with the maximum point number. To validate the effectiveness of our method, the anisotropic neighbors are applied to point data processing, such as normal estimation and point cloud denoising. Experimental results demonstrate that the proposed algorithm in the work is more time-consuming, but provides a more accurate result for point cloud processing by comparing with other kNN searching methods. The anisotropic neighborhood searched by our method can be used to normal estimation, denoising, surface fitting and reconstruction et al. for point cloud with sharp feature, and our method can provide more accurate result comparing with isotropic neighborhood.

To solve the challenge of single-channel blind image separation (BIS) caused by unknown prior knowledge during the separation process, we propose a BIS method based on cascaded generative adversarial networks (GANs). To ensure that the proposed method can perform well in different scenarios and to address the problem of an insufficient number of training samples, a synthetic network is added to the separation network. This method is composed of two GANs: a U-shaped GAN (UGAN), which is used to learn image synthesis, and a pixel-to-attention GAN (PAGAN), which is used to learn image separation. The two networks jointly complete the task of image separation. UGAN uses the unpaired mixed image and the unmixed image to learn the mixing style, thereby generating an image with the “true” mixing characteristics which addresses the problem of an insufficient number of training samples for the PAGAN. A self-attention mechanism is added to the PAGAN to quickly extract important features from the image data. The experimental results show that the proposed method achieves good results on both synthetic image datasets and real remote sensing image datasets. Moreover, it can be used for image separation in different scenarios which lack prior knowledge and training samples.

Finite-time cycle period for a quantum Otto machine implies that either an adiabatic stroke or an isochoric process proceeds in finite time duration. The quantum Otto refrigerators under consideration consist of two adiabatic strokes, where the system (isolated from the heat reservoir) undergoes finite-time unitary transformation, and two isochoric steps, where the system may not reach thermal equilibrium even at the respective ends of the two stages due to finite-time interaction intervals. Using two-time projective measurement method, we find the probability distribution functions of both coefficient of performance and cooling load, which are dependent on the time duration along each process. With these distributions we find the analytical expressions for the performance parameters as well as their fluctuations. We then numerically determine the performance and fluctuations for the refrigerator operating with a two-level system employed in a recent experimental implementation. Our results clarify the role of finite-time durations of four processes on the performance and fluctuations of the quantum Otto refrigerators.

In this paper we investigate the scattering mechanisms of viscous momentum transport in unitary Fermi gases below the pseudogap temperature T^{*} by opening almost all the elastic and inelastic scattering channels. For a given system Hamiltonian, we adopt a microscopic t-matrix approximation to determine the thermodynamical quantities, and we approach an equivalent three-fluid dynamics to calculate the viscous relaxation time τ by two kinds of elementary excitations. The exotic scattering processes raised by uncondensed Fermi pairs greatly decay τ and lead to a universal behavior of τ with temperature, which is closely related to the anomalous transport in a wide range of strongly correlated systems. For linking our findings of τ to the shear viscosity η, we present a Kubo-based expression of η by the stress-tensor correlation function with conserved vertex corrections, and we give an approximate relation for a possible experimental determination of τ. Our results fit well with measurements and are comparable with other theories. Moreover, we verify the newly proposed universal upper bound of the ratio of η and entropy density s in unitary Fermi gases.

Reducing user frustration over the failure to find a book in the library catalog, eliminating missing titles, and cleaning up other common database errors are tasks facing all libraries. Recently, the staff at Southern Polytechnic State University undertook a collection inventory using Palm Pilot technology. This article describes the one-year project and provides a detailed discussion of the procedures and equipment required to undertake this task. The experience at Southern Polytechnic State University suggests that library inventory is feasible and manageable. [ABSTRACT FROM AUTHOR]

We study the collective excitations of a trapped Bose-Einstein condensate for a large but finite number of atoms. Since our calculations go beyond the Thomas-Fermi approximation, the "quantum pressure" and the change of chemical potential due to the density fluctuations must be considered. The small kinetic energy enhancement and chemical potential reduction can't be neglected with respect to the strong inter-atomic interaction. The hydrodynamic equation is corrected for the large but finite number of atoms and its solution is obtained from perturbation theory. A variational calculation of the ground-state density yields explicit analytic expressions for all excitation energies as functions of the interaction strength for harmonic traps with spherical and cylindrical symmetries. Within the wide interaction ranges where the condition of perturbation calculation is satisfied, the calculated results agree well with those of the experiments and simulations. [ABSTRACT FROM AUTHOR]

This paper reports a cement-based 1−3 piezoelectric composite sensor for the characterization of shear stress in civil engineering structures. The sensor was fabricated using a cutting−filling method, in which the piezoelectric elements work in d15 shear mode. Its properties—such as piezoelectric constant, dielectric constant, electromechanical coupling coefficient, and density—have been systematically tested. By embedding two sensors into a concrete beam, we have further characterized its performance with a three point bending test technique. Results show that both sensors have very good accuracy, linearity, and frequency bandwidth. For instance, under a dynamic load of 2000 N at 10 HZ, the shear stresses measured by the two embedded sensors were 12.07 kPa and 12.01 kPa, slightly smaller than the calculated value of 12.5 kPa. Furthermore, the potential application of the sensor in monitoring acoustic signals in concrete was validated by knocking three arbitrary points of the beam. [ABSTRACT FROM AUTHOR]

Based on quantum thermodynamic processes, we make a quantum-mechanical (QM) extension of the typical heat engine cycles, such as the Carnot, Brayton, Otto, Diesel cycles, etc., with no introduction of the concept of temperature. When these QM engine cycles are implemented by an ideal gas confined in an arbitrary power-law trap, a relation between the quantum adiabatic exponent and trap exponent is found. The differences and similarities between the efficiency of a given QM engine cycle and its classical counterpart are revealed and discussed. [ABSTRACT FROM AUTHOR]

Based on counting statistics and Bogoliubov theory, we present a recurrence relation for the microcanonical partition function for a wealdy interacting Bose gas with a finite number of particles in a cubic box. According to this microcanonical partition function, we calculate numerically the distribution function, condensate fraction, and condensate fluctuations for a finite and isolated Bose-Einstein condensate. For ideal and weakly interacting Bose gases, we compare the condensate fluctuations with those in the canonical ensemble. The present approach yields an accurate account of the condensate fluctuations for temperatures close to the critical region. We emphasize that the interactions between excited atoms turn out to be important for moderate temperatures. [ABSTRACT FROM AUTHOR]

We consider the finite-time performance of a quantum Otto engine working between a hot squeezed and a cold thermal bath at inverse temperatures βh and βc(>βh) with (kB≡1)β=1/T. We derive the analytical expressions for work, efficiency, power, and power fluctuations, in which the squeezing parameter is involved. By optimizing the power output with respect to two frequencies, we derive the efficiency at maximum power as ηmp=(ηgenC)2/[ηgenC-(1-ηgenC)ln(1-ηgenC)], where the generalized Carnot efficiency ηgenC in the high-temperature or small squeezing limit simplifies to an analytic function of squeezing parameter γ: ηgenC=1-βh/[βccosh(2γ)]. Within the context of irreversible thermodynamics, we demonstrate that the expression of efficiency at maximum power satisfies a general form derived from nonlinear steady state heat engines. We show that, the power fluctuations are considerably increased, although the engine efficiency is enhanced by squeezing. [ABSTRACT FROM AUTHOR]

We investigate the finite-power performance of quantum heat engines working in the linear response regime where the temperature gradient is small. The engine cycles with working substances of ideal harmonic systems consist of two heat transfer and two adiabatic processes, such as the Carnot cycle, Otto cycle, and Brayton cycle. By analyzing the optimal protocol under maximum power we derive the explicitly analytic expression for the irreversible entropy production, which becomes the low dissipation form in the long duration limit. Assuming the engine to be endoreversible, we derive the universal expression for the efficiency at maximum power, which agrees well with that obtained from the phenomenological heat transfer laws holding in the classical thermodynamics. Through appropriate identification of the thermodynamic fluxes and forces that a linear relation connects, we find that the quantum engines under consideration are tightly coupled, and the universality of efficiency at maximum power is confirmed at the linear order in the temperature gradient. [ABSTRACT FROM AUTHOR]

We consider the efficiency at maximum power of a quantum Otto engine, which uses a spin or a harmonic system as its working substance and works between two heat reservoirs at constant temperatures Th and Tc (

We propose a quantum absorption refrigerator driven by photons. The model uses a four-level system as its working substance and couples simultaneously to hot, cold, and solar heat reservoirs. Explicit expressions for the cooling power Qc, and coefficient of performance (COP)ηcop are derived, with the purpose of revealing and optimizing the performance of the device. Our model runs most efficiently under the tight coupling condition, and it is consistent with the third law of thermodynamics in the limit T → 0. [ABSTRACT FROM AUTHOR]

A two-level atomic system as a working substance is used to set up a refrigerator consisting of two quantum adiabatic and two isochoric processes (two constant-frequency processes ωa and ωb with ωa < ωb), during which the two-level system is in contact with two heat reservoirs at temperatures Th, and Tc(

We consider the finite-time operation of a quantum heat engine whose working substance is composed of a two-level atomic system. The engine cycle, consisting of two quantum adiabatic and two quantum isochoric (constant-frequency) processes and working between two heat reservoirs at temperatures Th and Tc(

We generalize the quantum heat engine (QHE) model which was first proposed by Bender et al. [J. Phys. A 33, 4427 (2000)] to the case in which an ideal Fermi gas with an arbitrary number N of particles in a box trap is used as the working substance. Besides two quantum adiabatic processes, the engine model contains two isoenergetic processes, during which the particles are coupled to energy baths at a high constant energy Eh and a low constant energy Ec, respectively. Directly employing the finite-time thermodynamics, we find that the power output is enhanced by increasing particle number N (or decreasing minimum trap size LA) for given LA (or N), without reduction in the efficiency. By use of global optimization, the efficiency at possible maximum power output (EPMP) is found to be universal and independent of any parameter contained in the engine model. For an engine model with any particle-number N, the efficiency at maximum power output (EMP) can be determined under the condition that it should be closest to the EPMP. Moreover, we extend the heat engine to a more general multilevel engine model with an arbitrary ID power-law potential. Comparison between our engine model and the Carnot cycle shows that, under the same conditions, the efficiency η = 1 -- Ec&frac;Eh of the engine cycle is bounded from above the Carnot value ηc = 1 -- Tc&frac;Th. [ABSTRACT FROM AUTHOR]