286 results on '"Thomas, Roman K."'
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2. Evolutionary trajectories of small cell lung cancer under therapy
3. Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer
4. Therapeutic targeting of the mevalonate–geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer
5. Chromothripsis followed by circular recombination drives oncogene amplification in human cancer
6. Pulmonary cancers across different histotypes share hybrid tuft cell/ionocyte-like molecular features and potentially druggable vulnerabilities
7. A Tuft Cell–Like Signature Is Highly Prevalent in Thymic Squamous Cell Carcinoma and Delineates New Molecular Subsets Among the Major Lung Cancer Histotypes
8. A mechanistic classification of clinical phenotypes in neuroblastoma
9. MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I
10. Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes
11. Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer
12. Texture analysis of iodine maps and conventional images for k-nearest neighbor classification of benign and metastatic lung nodules
13. Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer
14. K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways
15. Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data
16. Concordance between Comprehensive Cancer Genome Profiling in Plasma and Tumor Specimens
17. Depletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death
18. MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer
19. Author Correction: LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells
20. CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer
21. Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment.
22. Comprehensive genomic profiles of small cell lung cancer
23. A framework for identification of actionable cancer genome dependencies in small cell lung cancer
24. Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data
25. LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells
26. Identifying Genotype-Dependent Efficacy of Single and Combined PI3K- and MAPK-Pathway Inhibition in Cancer
27. Assessing the Significance of Chromosomal Aberrations in Cancer: Methodology and Application to Glioma
28. Epidermal Growth Factor Receptor Variant III Mutations in Lung Tumorigenesis and Sensitivity to Tyrosine Kinase Inhibitors
29. An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells
30. Spatial Tumor Heterogeneity in Lung Cancer with Acquired Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance: Targeting High-Level MET-Amplification and EGFR T790M Mutation Occurring at Different Sites in the Same Patient
31. Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer
32. AATF/Che‐1 acts as a phosphorylation‐dependent molecular modulator to repress p53‐driven apoptosis
33. A crucial requirement for Hedgehog signaling in small cell lung cancer
34. Expression of Signaling Mediators Downstream of EGF-Receptor Predict Sensitivity to Small Molecule Inhibitors Directed Against the EGF-Receptor Pathway
35. CGARS: cancer genome analysis by rank sums
36. Overcoming Drug Resistance in ALK-Rearranged Lung Cancer
37. Predicting drug susceptibility of non--small cell lung cancers based on genetic lesions
38. Somatic mutations affect key pathways in lung adenocarcinoma
39. Bronchial and Peripheral Murine Lung Carcinomas Induced by T790M-L858R Mutant EGFR Respond to HKI-272 and Rapamycin Combination Therapy
40. Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain
41. Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing
42. Tumor VEGF: VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer
43. A transforming MET mutation discovered in non-small cell lung cancer using microarray-based resequencing
44. Comprehensive genomic characterization of squamous cell lung cancers
45. Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer
46. Osteoblastic Response in Patients with Non-small Cell Lung Cancer with Activating EGFR Mutations and Bone Metastases during Treatment with EGFR Kinase Inhibitors
47. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
48. A flexible rank-based framework for detecting copy number aberrations from array data
49. Integrative analysis of multi-omics data reveals the heterogeneity and signatures of immune therapy for small cell lung cancer.
50. Characterizing the cancer genome in lung adenocarcinoma
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