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586 results on '"Stewart AF"'

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1. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

2. Large-scale gene-centric analysis identifies novel variants for coronary artery disease

6. Genetically Determined Height and Coronary Artery Disease

7. Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

8. The European dimension for the mouse genome mutagenesis program

9. Homocysteine and coronary heart disease: Meta-analysis of MTHFR case-control studies, avoiding publication bias

10. Common Variants at 10 Genomic Loci Influence Hemoglobin A(1C) Levels via Glycemic and Nonglycemic Pathways

11. Erratum: BAC TransgeneOmics: A high-throughput method for exploration of protein function in mammals (Nature Methods (2008) vol. 5 (409-415))

12. Human β-cell proliferation and intracellular signaling: driving in the dark without a road map.

13. ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.

14. Regulated and reversible induction of adult human β-cell replication.

15. Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.

16. Parathyroid hormone-related protein enhances human ß-cell proliferation and function with associated induction of cyclin-dependent kinase 2 and cyclin E expression.

17. Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6.

18. The retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells.

19. Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo.

20. Tissue-specific deletion of the retinoblastoma protein in the pancreatic beta-cell has limited effects on beta-cell replication, mass, and function.

21. The cell cycle inhibitory protein p21cip is not essential for maintaining ß-cell cycle arrest or ß-cell function in vivo.

22. Evaluation of beta-cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21cip.

25. Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.

26. Genetic studies of body mass index yield new insights for obesity biology

27. New genetic loci link adipose and insulin biology to body fat distribution

28. Seamless site-directed mutagenesis in complex cloned DNA sequences using the RedEx method.

29. A Phase 1 single ascending dose study of pure oral harmine in healthy volunteers.

30. Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation.

31. Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system.

32. Developing an Injury-Free 15 Hour Preservation Protocol of Donor Porcine Kidneys Using Normothermic Machine Perfusion.

33. Select DYRK1A Inhibitors Enhance Both Proliferation and Differentiation in Human Pancreatic Beta Cells.

34. Transcriptional activation of the Myc gene by glucose in β-cells requires a ChREBP-dependent 3-D chromatin interaction between the Myc and Pvt1 genes.

35. Structure-Function Analysis of p57KIP2 in the Human Pancreatic Beta Cell Reveals a Bipartite Nuclear Localization Signal.

36. Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence.

37. Human Pancreatic α-Cell Heterogeneity and Trajectory Inference Analysis Using Integrated Single Cell- and Single Nucleus-RNA Sequencing Platforms.

38. Bone Mineral Density During and After Lactation: A Comparison of African American and Caucasian Women.

39. Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence.

40. ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex.

41. Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes β-cell subpopulations with dynamic transcriptome profiles.

43. Analysis of Operational Efficiency and Cost Differences between Local and General Anesthesia for Vitreoretinal Surgery.

45. Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats.

46. Disrupting the DREAM complex enables proliferation of adult human pancreatic β cells.

47. Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.

48. Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter mice.

49. Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation.

50. Improved dsDNA recombineering enables versatile multiplex genome engineering of kilobase-scale sequences in diverse bacteria.

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