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14. Curled up trabecular meshwork - A simple cause

Author

Rao, Aparna, Khan, Sardar, and Mukherjee, Sujoy

Subjects
Glaucoma, Health
Abstract

Byline: Aparna. Rao, Sardar. Khan, Sujoy. Mukherjee A 68-year-old male presented with redness in the right eye 1 week after surgery for open-angle glaucoma. Slit-lamp examination showed an intraocular pressure [...]

Published
2023

15. Healing responses at the angle after micro-invasive glaucoma surgery-an AS-OCT study.

Author

Rao, Aparna and Mukherjee, Sujoy

Subjects
*SCLERA, *VISUAL acuity, *VISUAL fields, *OPTICAL coherence tomography, *HEALING, *GLAUCOMA, *CATARACT surgery, *SCARS
Abstract

Purpose: To evaluate structural alterations and healing responses in the trabecular meshwork region with optical coherence tomography (AS-OCT) following after gonioscopy assisted transluminal trabeculotomy (GATT) and microincisional trabeculectomy (MIT). Methods: 73 eyes of 67 patients (M:F = 45:22) with ≥6 months of follow-up after MIT (n = 41) or GATT (n = 32) with or without combined cataract surgery were included for this prospective study. The angle as seen on AS-OCT at 1, 3, 6 months after surgery were evaluated for structural alterations like peripheral anterior synechiae (PAS), hyphema, and hyperreflective scarring responses. The scarring was graded according to the linear extent measured from the centre of the trabecular meshwork (TM) gutter to the sclera/cornea as mild (<250μ), moderate (250–500μ), and severe(˃500μ), while the pattern of scarring was graded as open saucer/gutter, closed gutter, and trench pattern. The association of the need for medication or surgical outcome and clinical variables and AS-OCT parameters including the pattern and severity of scarring were analysed using multivariate regression. Results: All eyes achieved significant reduction of IOP and number of medications with a final IOP of 15±3.2mm Hg at a mean follow-up of 8±32. months. While mild scarring was seen more common in MIT, severe scarring was seen in >65% of GATT eyes compared to 31% of MIT eye, p<0.001. An open saucer was equally seen in MIT and GATT while the trench pattern was more commonly seen in GATT eyes (>50%). Severe scarring in a trench pattern seemed to predict the need for medications for IOP control, though they independently did not seem to influence the final IOP or surgical outcome. Conclusion: A severe form of scarring in a trench pattern on AS-OCT predicted the need for glaucoma medications after MIGS surgery. Regular monitoring of the scarring responses by AS-OCT and clinical examination are necessary to identify those at need for medications after MIGS. [ABSTRACT FROM AUTHOR]

Published
2024
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20. International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module

Author

Desse, J.E., Maurizi, D.M., Montanini, A.M., Chaparro, G.J., Stagnaro, J.P., Romani, A., Bianchi, A.C., Álvarez, G., Palaoro, A., Bernan, M., Cabrera-Montesino, R., Domínguez, C., Rodríguez, C.G., Silva, C.G., Bogdanowicz, E., Riera, F.O., Benchetrit, G., Perez, I., Vimercati, J., Marcos, L.S., Ramasco, L., Caridi, M., Oyola, M.C., Rodríguez, M.C., Spadaro, M.L., Olivieri, M.S., Saul, P., Juarez, P.D., Pérez, R.H., Botta, P., Quintana, D.Q., Ríos, A.M., Chediack, V., Chilon, W., Alsayegh, Ameena Isa, Yaseen, Fatema Hasan, Hani, Lateefa Fardan, Sowar, Saleh Fakher, Magray, Tahira Anwar, Medeiros, E.A., Alves De Oliveira, A., Romario-Mendes, A., Fernandes-Valente, C., Santos, C., Escudeiro, D., Azevedo-Ferreira Lima, D., Azevedo-Pereira, D., Onzi-Siliprandi, E.M., Serpa-Maia, F., Aguiar-Leitao, F., Assuncao-Ponte, G., Dos Anjos-Lima, J., Olszewski, J., Harten Pinto Coelho, K., Alves De Lima, L.F., Mendonca, M., Maciel-Canuto Amaral, M.L., Tenorio, M.T., Gerah, S., Andrade-Oliveira-Reis, M., Moreira, M., Ximenes-Rocha Batista, M., Campos-Uchoa, R.S., Rocha-Vasconcelos Carneiro, R., Amaral De Moraes, R., Do Nascimento, S.C., Moreira-Matos, T., Lima-De Barros Araujo, T.M., De Jesus Pinheiro-Bandeira, T., Machado-Silva, V.L., Santos Monteiro, W.M., Hristozova, E., Kostadinov, E.D., Angelova, K., Velinova, V.A., Dicheva, V.J., Guo, X., Ye, G., Li, R., Song, L., Liu, K., Liu, T., Song, G., Wang, C., Yang, X., Yu, H., Yang, Y., Martínez, A., Vargas-García, A.R., Lagares-Guzmán, A., González, A.P., Linares, C., Ávila-Acosta, C., Santofimio, D., Yepes-Gomez, D., Marin-Tobar, D.A., Mazo-Elorza, D.P., Chapeta-Parada, E.G., Camacho-Moreno, G., Roncancio-Vill, G.E., Valderrama-Marquez, I.A., Ruiz-Gallardo, J.E., Ospina-Martínez, J.O., Osorio, J., Marín-Uribe, J.I., López, J.C., Gualtero, S., Rojas, J.R., Gomez-Nieto, K., Rincon, L.Y.M., Meneses-Ovallos, L., Canas-Giraldo, L.M., Burgos-Florez, L.D., Amaral-Almeida Costa, M., Rodriguez, M., Barahona-Guzmán, N., Mancera-Paez, O., Rios-Arana, P.A., Ortega, R., Romero-Torres, S.L., Pulido-Leon, S.M., Valderrama, S., Moreno-Mejia, V.M., Raigoza-Martinez, W., Villamil-Gomez, W., Pardo-Lopez, Y.A., Argüello-Ruiz, A., Solano-Chinchilla, A., Muñoz-Gutierrez, G.A., Calvo-Hernández, I., Maroto-Vargas, L., Zuniga, M.A., Valverde-Hernandez, M., Chavarria-Ugalde, O., Herrera, B., Díaz, C., Bovera, M.M., Cevallos, C., Pelaez, C., Jara, E., Delgado, V., Coello-Gordon, E.E., Picoita, F., Guerrero-Toapant, F.M., Valencia, F., Santacruz, G., Gonzalez, H., Pazmino, L.N., Garcia, M.F., Arboleda, M., Lascano, M., Alquinga, N., Ramírez, V., Yousef, Reham H.A., Moustafa, Abd El Moniem, Ahmed, A., Elansary, A.M., Ali, Ahmad Mahmoud, Hasanin, Ahmed, Messih, Antoine Abdel, Ramadan, Arwa, El Awady, B.A., Hassan, D.M., Abd El Aziz, Doaa, Hamza, Hala, Agha, Hala Mounir, Ghazi, Islam Abdullorziz, ElKholy, J., Fattah, May Abdel, Elanany, Mervat, Mansour, M., Haleim, M.M.A., Fouda, R., El-Sherif, Rasha Hamed, Bekeit, S., Bayani, V., Elkholy, Y.S., Abdelhamid, Y.M., Salah, Zeinab, Rivera, D.M., Chawla, A., Manked, A.N., Azim, A., Mubarak, A., Thakur, A., Dharan, A.V., Patil, A., Sasidharan, A., Bilolikar, Anil Kumar, Anirban Karmakar, A., Mathew, A.M., Kulkarni, Anuja, Agarwal, Anuradha, Sriram, Anuradha, Dwivedy, A., Dasgupta, Arnab, Bhakta, A., Suganya, Arul Rose, Poojary, A., Mani, Ashwin Kumar, Sakle, Asmita, Abraham, Babu K., Padmini, Baby, Ramachandran, B., Ray, Banambar, Pati, Basanta Kumar, Chaudhury, Bhaskar Narayan, Mishra, Biraj Mohan, Biswas, S., Saibala, M. Bri, Jawadwala, Burhan Q., Rodrigues, C., Modi, Chirag, Patel, Chirag, Khanna, D.K., Devaprasad, Dedeepiya, Divekar, Deepa, Aggarwal, Deepesh G., Divatia, J.V., Zala, Dolatsinh, Pathrose, Edwin, Abubakar, Fazil, Chacko, Felcy, Gehlot, G.S., Khanna, Gautam, Sale, H.K., Roy, Indranil, Shelgaonkar, Jayant, Sorabjee, Jehangir, Eappen, Jincy, Mathew, Justin, Pal, Jyotishka, Varma, Karthikeya, Joshi, Kashmira Limaye, Sandhu, Kavita, Kelkar, R., Ranganathan, Lakshmi, Pushparaj, L., Lavate, Madhav, Latha, Madhavi, Suryawanshi, Madhupriya, Bhattacharyya, M., Kavathekar, Maithili, Agarwal, Manoj Kumar, Patel, Mayur, Shah, Mehul, Sivakumar, M.N., Kharbanda, Mohit, Bej, Mrinmoy, Potdar, Mrunalini, Chakravarthy, M., Karpagam, M., Myatra, S.N., Gita, N., Rao, N.P., Sen, N., Ramakrishnan, N., Jaggi, N., Saini, N., Pawar, N.K., Modi, Nikhil, Pandya, Nirav, Mohanty, Nisith, Thakkar, Pooja, Joshi, Pradnya, Sahoo, Prafulla Kumar, Nair, Pravin Kumar, Kumar, Priyadarshini Senthil, Patil, Priyanka, Mukherjee, Purnima, Mathur, P., Shah, Purvi, Sukanya, R., Arjun, Rajalakshmi, Chawla, Rajesh, Gopalakrishnan, Ram, Venkataraman, Ramesh, Raut, S., Krupanandan, Ravikumar, Tejam, Reshma, Misra, Richa, Debroy, Ritesh, Saranya, S., Narayanan, Sajith, Mishra, Sanghamitra, Saseedharan, Sanjith, Sengupta, Sankar, Patnaik, S.K., Sinha, Saswati, Blessymole, Seelas, Rohra, Seema, Rajagopal, Senthilkumar, Mukherjee, Shanta, Sengupta, Sharmila, John, Sheeba, Bhattacharya, Shefali, Sijo, Bhattacharyya, Sinchan, Singh, S., Sohanlal, T., Vadi, Sonali, Dalal, S.S., Todi, S.K., Kumar, Subodh, Kansal, Sudha, Misra, Sudhjan, Bhattacharyya, Sudipta, Nirkhiwale, Suhas, Purkayastha, Sujit Kar, Mukherjee, Sujoy, Sahu, S., Sharma, Sunil, Kumar, Suresh, Basu, S., Shetty, S., Shah, S., Singhal, T., Francis, Thara, Anand, Thejasvini, Venkateshwar, V., Thomas, Valsa, Kothari, V., Velupandi, Kantroo, Vini, Sitohang, Gortap, Kadarsih, Retno, Sanaei, Anahita, Maghsudi, Behzad, Sabetian, Golnar, Masjedi, Mansoor, Alebouyeh, Masoud, Sherafat, Somayeh Jahani, Mohamed, Yassir Khidir, Al Khamis, Abdulrahim, Alsaadi, Adnan Soliman, Al-Jarie, Ahmed Abdoh, Mutwalli, Aisha Hassan, Rillorta, A.S.K., Thomas, Anumol, Kelany, Ashraf, Manao, Athena, Alamri, Dhaffer Moghram, Santiago, E.B., Cruzpero, E.P., Sawan, Fahad Ahmed, Al Qasmah, Fatima Abdullah, Alabdaly, Haeel, Al-Dossary, Hajer Am, Ahmed, Hala, Roshdi, Hala, Al-Alkami, Halima Yahia, Hanafi, Hana, Ammari, Hassan Eisa, Hani, Hatem Mohd Al, Asiri, Ibrahim A.M. Alzaydani, Mendoza, Jeffrey Asidera, Philipose, Jomol, Selga, Joy Ola, Kehkashan, Ghalilah, Khalid Mohammed, Redito, Leide Shyrine, Josph, L., Al-Alawi, M., Al-Gethamy, Manal Mansour, Madco, Marjory, Manuel, M.G., Girvan, M., Aldalaton, Mervat, De Guzman, M., Alkhamaly, Modhi, Masfar, Mohammad, Karrar, Mohammed Ahmed Ali, Al Azmi, Munayfa Musallam, Quisai, Myrna Lim, Torres, Myrna Misador, Al-Abdullah, N., Tawfic, Nader Ahmed, Elsayed, Nashwa, Abdulkhalik, Nawal Salah, Bugis, Nehad Abdulshakour, Ariola, Neilia Cardinal, Gad, N., Alghosn, Nesreen, Tashkandi, Nidal, Zharani, N. Al, De Vera, P.A., Krishnan, Radhika, Al Shehri, Raed Hassan, Jaha, Rasha Nour Aldeen, Thomas, Reny, Cresencia, Rhea Lynn, Penuliar, R., Lozada, R.V., Al Qahtani, S., Twfik, Sameh, Al Faraj, Sarah Hassan, El-Sherbiny, Sherin, Alih, Siti Jhulmina B., Briones, Solita, Bukhari, Syed Zahid, Alotaibi, Tariq Saad Abdulhadi, Gopal, Uma, Nair, Usha, Abdulatif, Wael Abdulrahman, Hussain, Waleed Mohd, Demotica, Wynndale Mae, Spahija, G., Baftiu, N., Gashi, A., Omar, Abeer A., Mohamed, A.M., Rebello, F.M., Almousa, Haifaa Hassan, Abdo, Naglaa Mahmoud, George, S.M., Khamis, Soad, Thomas, Suja, Ahmad Zaatari, A., Anwar Al Souheil, A., Ayash, H., Zeid, I., Tannous, J., Zahreddine, N.K., Ahmadieh, R., Mahfouz, T., Kardas, T., Tanzi, V., Kanafani, Z., Hammoud, Z., Dagys, A., Grinkeviciute, D., Kevalas, R., Kondratas, T., Petrovska, Milena, Popovska, Katja, Mitrev, Zan, Miteva, Zaneta Bogoevska, Jankovska, Katerina, Guroska, Snezana Tufekcievska, Gan, Chin Seng, Othman, Ainul Auzani, Yusof, Aliza Mohamad, Abidin, Anis Siham Zainal, Aziz, Fadzlina Abdul, Weng, Foong Kit, Zainol, Hasimah, Bakar, Kamal Bashar Abu, Lum, Lucy Chai See, Mansor, Marzida, Zaman, Mazuin Kamarul, Jamaluddin, Mohamad Fadhil Hadi, Hasan, Mohd Shahnaz, Rahman, Raha Abdul, Zaini, Rhendra Hardy Mohamad, Zhazali, Rosliza, Sri Ponnampala, Sasheela Sri La, Chuah, Soo Lin, Shukeri, Wan Fadzlina Wan Mohd, Hassan, Wan Nazaruddin Wan, Yusoff, Wan Nurbayah Wan, Mat, Wan Rahiza Wan, Cureno-Diaz, M.A., Aguirre-Avalos, G., Flores-Alvarado, A., Cerero-Gudino, A., Zamores-Pedroza, A., Cano-Munoz, B., Hernandez-Chena, B.E., Carreon-Martinez, C.C., Coronado-Magana, H., Corona-Jimenez, F., Rodriguez-Noriega, E., Alcala-Martinez, E., Gonzalez-Diaz, E., Guerra-Infante, F.M., Arteaga-Troncoso, G., Martinez-Falcon, G., Leon-Garnica, G., Delgado-Aguirre, H.A., Perez-Gomez, H.R., Sosa-Gonzalez, I.E., Galindo-Olmeda, J.A., Ayala-Gaytan, J.J., Rodriguez-Pacheco, J., Zamorano-Flores, L., Lopez-Pulgarin, J.A., Miranda-Novales, M.G., Ramírez, M., Lopez-Hurtado, M., Lozano, M., Gomez, M.E., Sanchez-Castuera, M.E., Kasten-Monges, M., Gonzalez-Martinez, M., Sanchez-Vargas, M., Culebro-Burguet, M.C., Altuzar-Figueroa, M.A., Mijangos-Mendez, J.C., Ramires, O.G., Espinosa, O.S., De Leon-Escobedo, R., Salas-Flores, R., Ruiz-Rendon, R., Petersen-Morfin, S., Aguirre-Diaz, S.A., Esparza-Ahumada, S., Vega-Gonzalez, S., Gaona-Flores, V., Monroy-Colin, V.A., Cruz-Rivera, Z., Bat-Erdene, A., Narankhuu, Batsaikhan, Choijamts, Batsuren, Tuvdennyam, Battsetseg, Batkhuu, Byambadorj, Chuluunchimeg, K.H., Enkhtsetseg, D., Batjargal, G., Bayasgalan, G., Dorj, M., Mendsaikhan, Naranpurev, Baatar, Otgon, Suvderdene, P., Baigalmaa, S., Khajidmaa, T., Begzjav, Tsolmon, Tsuyanga, Ariyasuren, Z., Zeggwagh, A.A., Berechid, K., Abidi, K., Madani, N., Abouqal, R., Koirala, Anjeela, Giri, Rashmi, Sainju, Samana, Acharya, Subhash Prasad, Ahmed, Abeera, Raza, Aun, Parveen, Azra, Sultan, Faisal, Khan, Maria, Paul, Nadeem, Daud, Nargis, Yusuf, Sana, Nizamuddin, Summiya, Garcia-Mayorca, E., Castaño, E.G., Moreno-Castillo, J.L., Ballinas-Aquino, J.M., Lara, L., Vargas, M., Rojas-Bonilla, M.I., Ramos, S.J., Mapp, T., De Iturrado, V., La Hoz Vergara, C.E., Linares-Calderon, C.F., Moreno, D., Ramirez, E., Ramírez Wong, F.M., Montenegro-Orrego, G.M., Sandoval-Castillo, H.R., Pichilingue-Chagray, J., Mueras-Quevedo, J., Aibar-Yaranga, K.F., Castillo-Bravo, L.I., Santivanez-Monge, L.M., Mayorga-Espichan, M.J., Rosario-Tueros, M.L.G., Changano-Rodriguez, M.V., Salazar-Ramirez, N.E., Marquez-Mondalgo, V.A., Tajanlangit, Anna Lyn N., Tamayo, Arnefelina S., Llames, Cristina Mari Jean P., Labro, Ever, Dy, Ana P., Fortin, J.D., Bergosa, L.D., Salvio, L.G., Bermudez, V., Sg-Buenaflor, M.C., Trajano, M.F., Mendoza, M.T., Javellana, O.P., Maglente, R.R., Arreza-Galapia, Y., Navoa-Ng, J.A., Kubler, A., Barteczko-Grajek, B., Dragan, B., Zurawska, M., Mikaszewska-Sokolewicz, M., Zielinska, M., Ramos-Ortiz, G.Y., Florin-Rogobete, A., Vlad, C. Daliborca, Muntean, D., Sandesc, D., Papurica, M., Licker, M., Bedreag, Ovidiu Horea, Popescu, R., Grecu, S.D., Dumitrascu, V., Molkov, A., Galishevskiy, D., Furman, M., Simic, A., Lekic, D., Ristic, G., Eremija, J., Kojovic, J., Nikolic, L., Bjelovic, M., Lesnakova, A., Hlinkova, S., Gamar-Elanbya, M.O., Supa, Namphon, Prasan, Pornpheth, Pimathai, Rungratchanee, Wanitanukool, Suthinee, Somabutr, Suwara, Ben-Jaballah, N., Borgi, A., Bouziri, A., Dilek, A., Oncul, A., Kaya, A., Demiroz, Ali Pekcan, Gunduz, A., Ozgultekin, A., Inan, Asuman, Yalcin, A.N., Ramazanoglu, A., Engin, A., Willke, A., Meco, Basak Ceyda, Aygun, C., Bulut, C., Uzun, C., Becerik, C., Hatipoglu, Cigdem Ataman, Guclu, Cigdem Yildirim, Ozdemir, D., Yildizdas, D., Ugurcan, D., Azak, E., Guclu, E., Yilmaz, Esmeray Mutlu, Sebnem-Erdinc, F., Sirmatel, F., Ulger, F., Sari, Ferhat, Kizilates, Filiz, Usluer, G., Ceylan, G., Ersoz, G., Kaya, G., Ertem, Gunay Tuncer, Senol, G., Agin, Hasan, Cabadak, Hatice, Yilmaz, H., Sungurtekin, Hulya, Zengin, Humeyra, Turgut, H., Ozgunes, I., Devrim, I., Erdem, I., Işcanlı, Inşa Gul Ekiz, Bakir, M. Mehmet, Geyik, M.F., Oral, M., Meric, M., Cengiz, M., Ozcelik, M., Altindis, M., Sunbul, M., Elaldi, N., Kuyucu, N., Unal, N., Oztoprak, N., Yasar, N., Erben, Nurettin, Bayram, Nuri, Dursun, Oguz, Karabay, Oguz, Coskun, O., Horoz, Ozden Ozgur, Turhan, Ozge, Sandal, Ozlem Sarac, Tekin, Recep, Esen, Saban, Erdogan, Selvi Yener, Unal, Serhat, Karacorlu, Sevim, Sen, Suha, Sacar, Suzan, Yarar, Volkan, Oruc, Yeliz, Sahip, Yusuf, Kaya, Zeynep, Philip, Anamma, Elhoufi, Ashraf, Alrahma, Hussain, Sachez, E., Perez, F., Empaire, G.D., Vidal, H., Montes-Bravo, L., Guzman Siritt, M.E., Orozco, N., Navarrete, N., Ruiz, Y., De Anez, Z. Duran-Gil, Van Trang, Dang Thi, Minh, Dao Quang, Co, Dao Xuan, Anh, Dinh Pham Phuong, Thu, Le Thi Anh, Tuyet, Le Thi Diem, Nguyet, Le Thi Thu, Chau, Ngo uy, Binh, Nguyen Gia, Tien, Nguyen Phuc, Anh, Nguyen Quoc, Hang, Phan Thi, Hanh, Tran Thi My, Hang, Tran Thi Thuy, Thu, Truong Anh, Thoa, Vo Thi Hong, Rosenthal, Víctor Daniel, Al-Abdely, Hail M., El-Kholy, Amani Ali, AlKhawaja, Safa A Aziz, Leblebicioglu, Hakan, Mehta, Yatin, Rai, Vineya, Hung, Nguyen Viet, Kanj, Souha Sami, Salama, Mona Foda, Salgado-Yepez, Estuardo, Elahi, Naheed, Morfin Otero, Rayo, Apisarnthanarak, Anucha, De Carvalho, Braulio Matias, Ider, Bat Erdene, Fisher, Dale, Buenaflor, Maria Carmen S.G., Petrov, Michael M., Quesada-Mora, Ana Marcela, Zand, Farid, Gurskis, Vaidotas, Anguseva, Tanja, Ikram, Aamer, Aguilar de Moros, Daisy, Duszynska, Wieslawa, Mejia, Nepomuceno, Horhat, Florin George, Belskiy, Vladislav, Mioljevic, Vesna, Di Silvestre, Gabriela, Furova, Katarina, Ramos-Ortiz, Gloria Y., Gamar Elanbya, May Osman, Satari, Hindra Irawan, Gupta, Umesh, Dendane, Tarek, Raka, Lul, Guanche-Garcell, Humberto, Hu, Bijie, Padgett, Denis, Jayatilleke, Kushlani, Ben Jaballah, Najla, Apostolopoulou, Eleni, Prudencio Leon, Walter Enrique, Sepulveda-Chavez, Alejandra, Telechea, Hector Miguel, Trotter, Andrew, Alvarez-Moreno, Carlos, and Kushner-Davalos, Luis

Published
2016
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23. 'Intraoperative predictors for clinical outcomes after microinvasive glaucoma surgery".

Author

Rao, Aparna and Mukherjee, Sujoy

Subjects
*TRYPAN blue, *TREATMENT effectiveness, *GLAUCOMA, *INTRAOCULAR pressure, *CATARACT surgery, *ARACHNOID cysts
Abstract

Purpose: To evaluate the clinical applicability of intraoperative predictors for surgical outcomes after gonioscopy-assisted transluminal trabeculotomy (GATT) and microincisional trabeculectomy (MIT). Methods: Consecutive patients with primary, or secondary glaucoma (trauma, aphakic, or status post-retinal surgeries) with uncontrolled IOP>21mm Hg, who were scheduled to undergo GATT or MIT with or without significant cataract surgery, at a tertiary eye centre in East India between September 2021 to March 2023, were included. All surgeries were done by a single surgeon. Blanching and Trypan blue (0.4%) staining after intracameral injection using a 25 canula, were analysed in each video. The extent/pattern of blanching and blue staining in each eye was analysed objectively using an overlay of a circle with 12 sectors and a protractor tool to quantify the degrees or quadrants of blanching/staining. Multivariate regression was used to identify predictors for surgical success or the need for medications after surgery. Result: Of 167 eyes that were included (male: female- 134: 33), 49 eyes and 118 eyes underwent GATT and MIT, respectively, with 81 of 167 eyes undergoing concurrent cataract surgery. All eyes had a significant reduction in the number of medications after surgery. Blanching was seen in 154 of 167 eyes in a mean of 2±1.8 quadrants with 41% of eyes showing a blanching effect in >3 quadrants. Of 99 of 167 eyes where Trypan blue staining was assessed, staining in a venular, diffuse haze, or reticular pattern of staining was seen in 73 eyes, 26 eyes showed blue staining in >2 quadrants, with 16% staining in >3 quadrants. Surgical success was not predicted by the quadrants of blanching, blue staining, or other clinical variables (age, visual field, baseline intraocular pressure, type of surgery). The variables significantly predicting the need for medications included blanch (r = -0.1, p = 0.03), and blue staining (r = -0.1, p = 0.04) in <2 quadrants. Conclusions: Blanching and Trypan blue staining in >2 quadrants after GATT or MIT can serve as surrogate predictors for the need for medications. However more studies are mandated to find predictors for surgical success after GATT or MIT. [ABSTRACT FROM AUTHOR]

Published
2023
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24. Effect of Exercise on ECG Components and their Correlation with Body Mass Index among Young Asymptomatic Obese and Non-obese Individuals: A Cross-sectional Study An Enigma of its Own: A Case Report.

Author

MUKHERJEE, SUJOY, BANERJEE, GOUTAM, and MUKHERJEE, SANHITA

Subjects
*BODY mass index, *OBESITY, *ORTHOSTATIC hypotension, *CARDIOVASCULAR diseases, *CROSS-sectional method, *PEARSON correlation (Statistics), *AEROBIC exercises
Abstract

Introduction: The worldwide higher prevalence of obesity is currently one of the most important reasons for the occurrence of several health disorders, along with an increased risk of mortality and morbidity. However, the magnitude of the effect of sub-maximal aerobic exercise on cardiac autonomic and electrical function among Indian obese individuals has yet to be established. Aim: To evaluate the effect of exercise on ECG components and their correlation with Body Mass Index (BMI) among young asymptomatic obese and non-obese individuals, in order to assess the risk for developing Cardiovascular Diseases (CVD) in the future. Materials and Methods: An observational cross-sectional study was conducted at the Autonomic Research Laboratory of the Physiology Department at RG Kar Medical College and Hospital, Kolkata, between January 2017 to December 2017. Two hundred healthy medicos were divided into two groups: Obese (BMI =25 kg/m²; n=88) and non-obese (BMI =18.5 to =23 kg/m²; n=112). Resting Blood Pressure (BP) was manually recorded, followed by the recording of long lead-II ECG in the supine posture both at rest and ten minutes after submaximal (50% VO2max) aerobic exercise on a treadmill using the modified Bruce protocol and following the Astrand-Rhyming nomogram. The HR, QT interval, and RR interval were recorded from the lead-II ECG. The measured QT interval was corrected using Bazett's formula (QTC=QT/vRR). The results were analysed using both unpaired and paired t-tests and the Pearson correlation coefficient in Graphpad-Quickcalc software. Results: Significant prolongation of the QTc interval both at rest (p-value: 0.019) and after exercise (p-value: 0.044), along with delayed Heart Rate Recovery (HRR) (p-value: 0.001), were observed among the obese compared to the non-obese population. Additionally, a significantly positive linear correlation was observed between BMI and ECG components at rest (BMIRHR: r:+0.293; p: 0.005 and BMI-QTc Interval: r:+0.226; p-value: 0.034) and during the recovery state (BMI-HRR: r:+0.42; p-value: 0.00004 and BMI-QTc Interval: r:+0.365; p-value: 0.0004), only among the obese. Conclusion: At rest, obese individuals had an elevated QTc, which could be due to alterations in cardiac autonomic function, along with a significant positive correlation between BMI and RHR, indicating lower aerobic fitness in this population. Prolongation of the QTc interval, delayed decrease in HR, and a significant positive correlation with BMI after exercise in obese individuals indicated myocardial repolarisation instability, autonomic dysfunction, and an increased risk of out-of-hospital sudden cardiac events in these individuals. [ABSTRACT FROM AUTHOR]

Published
2023
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27. The Generalized Kauffman-Harary Conjecture is True

Author

Bakshi, Rhea Palak, Guo, Huizheng, Montoya-Vega, Gabriel, Mukherjee, Sujoy, and Przytycki, Józef H.

Subjects
LOW-DIMENSIONAL MANIFOLDS (TOPOLOGY), Knot theory, FOS: Mathematics, ddc:510, Mathematics
Abstract

For a reduced alternating diagram of a knot with a prime determinant 𝑝�, the Kau man-Harary conjecture states that every non-trivial Fox 𝑝�-coloring of the knot assigns di erent colors to its arcs. In this paper, we prove a generalization of the conjecture stated nineteen years ago by Asaeda, Przytycki, and Sikora: for every pair of distinct arcs in the reduced alternating diagram of a prime link with determinant 𝛿�, there exists a Fox 𝛿�-coloring that distinguishes them., arXiv

Published
2023

28. International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

Author

Maurizi, Diego Marcelo, Montanini, Adriana, Spadaro, Maria Laura, Marcos, Lorenzo Santiago, Botta, Priscila, Jerez, Florencia Maria, Chavez, Maria Constanza, Ramasco, Lucia, Colqui, Maria Isabel, Olivieri, Maria Silvia, Rearte, Ana Silvia, Correa, Gladys Edith, Juarez, Paola Deolinda, Gallardo, Paola Fabiana, Brito, Miriam Patricia, Mendez, Gabriel Horacio, Valdez, Julia Rosa, Cardena, Lorena Paola, Harystoy, Jose Maria, Chaparro, Gustavo Jorge, Rodriguez, Claudia Gabriela, Toomey, Rodolfo, Caridi, Maria, Viegas, Monica, Bernan, Marisa Liliana, Romani, Adriana, Dominguez, Claudia Beatriz, Davalos, Luis Kushner, Richtmann, Rosana, Silva, Camila Almeida, Rodrigues, Tatiane T., Filho, Amaury Mielle, Seerig Palme, Ernandi Dagoberto, Besen, Aline, Lazzarini, Caroline, Cardoso, Caroline Batista, Azevedo, Francisco Kennedy, Pinheiro, Ana Paula Fontes, Camacho, Aparecida, De Carvalho, Braulio Matias, De Assis, Maria Jose Monteiro, Carneiro, Ana Paula Vasconcelos, Canuto, Maria Lilian Maciel, Pinto Coelho, Keyla Harten, Moreira, Tamiris, Oliveira, Agamenon Alves, Sousa Colares, Marcela Maria, De Paula Bessa, Marcia Maria, Gomes Bandeira, Tereza De Jesus Pinheiro, De Moraes, Renata Amaral, Campos, Danilo Amâncio, De Barros Araújo, Tânia Mara Lima, Freitas Tenório, Maria Tereza, Amorim, Simone, Amaral, Manuela, Da Luz Lima, Julianne, Pino Da Silva Neta, Lindalva, Batista, Caphiane, De Lima Silva, Fabio Jorge, Ferreira De Souza, Maria C., Arruda Guimaraes, Katia, Marcia Maluf Lopes, Julia, Nogueira Napoles, Karina M., Neto Avelar, Lorena Luiza Silva, Vieira, Lilian Aguiar, Gustavo De Oliveira Cardo, Luis, Takeda, Christianne F.V., Ponte, Glaydson A., Eduardo Aguiar Leitão, Fco, De Souza Kuchenbecker, Ricardo, Pires Dos Santos, Rodrigo, Maria Onzi Siliprandi, Erci, Fernando Baqueiro Freitas, Luiz, Martins, Ianick Souto, Casi, Daiane, Maretti Da Silva, Maria Angela, Blecher, Sergio, Villins, Margarete, Salomao, Reinaldo, Oliveira Castro, Solange Regina, Da Silva Escudero, Daniela V., Andrade Oliveira Reis, Mariana, Mendonca, Marcelo, Furlan, Valter, Claudio do Amaral Baruzzi, Antonio, Sanchez, Tarquino Eristidesg, Moreira, Marina, Vasconcelos de Freitas, Wania, Passos de Souza, Leonardo, Velinova, Velmira Angelova, Hadjieva, Nassya, Petrov, Michael M., Karadimov, Dimitar Georgiev, Kostadinov, Emil D., Dicheva, Violeta Jivkova, Wang, Chaohua, Guo, Xiuqin, Geng, Xihua, Wang, Shufang, Zhang, Jinzhi, Zhu, Ling, Zhuo, Shufang, Guo, Chunli, Lili, Tao, Ruisheng, Li, Kun, Liu, Yang, Xuesong, Yimin, Li, Pu, Mao, Changan, Li, Shumei, Yiang, Kangxiong, Wu, Meiyi, Lin, Ye, Guxiang, Ziqin, Xu, Yao, Suo, Liqiang, Song, Marino Cañas Giraldo, Luis, Margarita Trujillo Ramirez, Elsa, Rios, Paola Andrea, Carlos Torres Millan, Juan, Giovanny Chapeta Parada, Edwin, Eduardo Mindiola Rochel, Andres, Corchuelo Martinez, Andres H., Marãa Perez Fernandez, Ana, Guzman, Nayide Barahona, Guzman, Alfredo Lagares, Ferrer, Marena Rodriguez, Vega, Yazmin Leon, Munoz, Heidi Johanna, Moreno, Germán Camacho, Romero Torres, Sandra Liliana, Hernandez, Herlidia Taboada, Valderrama MarquezClaudia Linares, Ismael A., Valencia, Monica Espinosa, Corrales, Lusayda Sanchez, Bonilla, Sandra Milena, Ivan Marin Uribe, Jorge, Gomez, David Yepes, Martinez, Javier Ospina, Dary Burgos Florez, Luz, Osorio, Johanna, Santofimio, Dagoberto, Cortes, Lorena Matta, Villamil-Gomez, Wilmer, Gutierrez, Gabriel Munoz, Ruiz, Adela Arguello, Fuentes, Carlos Gonzalez, Chinchilla, Antonio Solano, Hernandez, Ivar Calvo, Ugalde, Olber Chavarria, Garcell, Humberto Guanche, Perez, Clara Morales, Bardak, Selin, Ozkan, Sumru, Mejia, Nepomuceno, Puello Guerrero Glenny Mirabal, Adrian M., Delgado, Margarita, Severino, Ramona, Lacerda, Eliesel, Tolari, Gilda, Bovera, María Marcela, Pinto, Diego Barahona, González, Pedro Fernández, Santacruz, Gasdali, Alquinga, Nelly, Zaruma, Celso, Remache, Nelson, Morocho, Diego, Arboleda, Mario, Zapata, Mario Cadena, Garcia, Maria Fernanda, Picoita, Fabricio, Velez, Jorge, Valle, Marcia, Yepez, Estuardo Salgado, Tutillo, Diego Morocho, Mora, Ricardo Arteaga, Padilla, Andrea Peña, Chango, Mayra, Cabezas, Karina, Tenorio López, Shirley, Lucía Bonilla Escudero, Ana, Sánchez, Gladys Tatiana, Alberto Gonzalez Flores, Hugo, Ghazi, Islam Abdullorziz, Hassan, Mohamed, Ismail, Ghada A., Hamed, Reham, Abdel-Halim, Mona Mohiedden, El-Fattah, May Abd, Abdel-Aziz, Doaa, Seliem, Zeinab Salah, Elsherif, Rasha Hamed, Dewdar, Reham Ali, Mohmed, Abeer Ahmed, Abdel-Fatteh Ahmed, Lamiaa, De Jesus Machuca, Lilian, Bran De Casares, Concepcion, Kithreotis, Prokopis, Daganou, Maria, Veldekis, Dimitrios, Kartsonaki, Maria, Gikas, Achilleas, Luque Torres, Marco Tulio, Padgett, Denis, Rivera, Doris Maribel, Jaggi, Namita, Rodrigues, Camilla, Shah, Bhagyesh, Parikh, Keyur, Patel, Jigar, Thakkar, Riya, Chakravarthy, Murali, Gokul, B.N., Sukanya, R., Pushparaj, Leema, Vini, Thejas, Rangaswamy, Sukanya, Patnaik, Saroj Kumar, Venkateshwar, Vempati, John, Biju, Dalal, Shamsher, Sahu, Suneeta, Sahu, Samir, Ray, Banambar, Misra, Sudhiranjan, Mohanty, Nisith, Mishra, Biraj Mohan, Sahoo, Prafulla, Parmar, Naresh, Mishra, Sanghamitra, Pati, Basanta Kumar, Singh, Santosh, Pati, Bhabani Shankar, Panda, Aparajita, Banergee, Swarna, Padhihari, Dipankar, Samal, Soumya, Varma, Karthikeya, Suresh Kumar, Velu Pandi, Gopalakrishnan, Ram, Ramakrishnan, Nagarajan, Abraham, Babu Kuruvilla, Rajagopal, Senthilkumar, Venkatraman, Ramesh, Mani, Ashwin Kumar, Devaprasad, Dedeepiya, Ranganathan, Lakshmi, Francis, Thara, Cherain, Kotturathu Mammen, Ramachandran, Bala, Krupanandan, Ravikumar, Muralidharan, S., Karpagam, Murali, Padmini, Baby, Saranya, S., Kumar, Siva, Pandya, Nirav, Kakkar, Rajesh, Zompa, Tenzin, Saini, Narinder, Samavedam, Srinivas, Jagathkar, Ganshyam, Nirkhiwale, Suhas, Gehlot, G.S., Bhattacharya, Shefali, Sood, Sanjeev, Singh, Suman, Singh, Sanjeev, Todi, Subhash Kumar, Bhattacharyya, Mahuya, Bhakta, Arpita, Basu, Susmita, Agarwal, Anuradha, Agarwal, Manoj, Kharbanda, Mohit, Sengupta, Sankar, Karmakar, Anirban, Gupta, Debkishore, Sarkar, Ajoy Krishna, Dey, Rimita, Bhattacharya, Chandramouli, Chandy, Mammen, Ramanan, V.R., Mahajan, Aseem, Roy, Manas, Bhattacharya, Sanjay, Sinha, Saswati, Roy, Indranil, Gupta, Umesh, Mukherjee, Sujoy, Bej, Mrinmoy, Mukherjee, Purnima, Baidya, Sumana, Azim, Afzal, Sakle, Asmita Sagar, Sorabjee, Jehangir Soli, Potdar, Mrunalini Subhash, Subhedar, Vaibhavi R., Udwadia, F.E., Francis, Hena, Dwivedy, Arpita, Binu, Sheena, Shetty, Suvin, Nair, Pravin Kumar, Khanna, Devendra K., Chacko, Felcy, Blessymole, Seelas, Mehta, Preeti Rajeev, Singhal, Tanu, Shah, Sweta, Kothari, Vatsal, Naik, Reshma, Patel, Mayur Harshadrai, Aggarwal, Deepesh Gokulchand, Jawadwala, Burhanuddin Qutbuddin, Pawar, Niketa Kaul, Kardekar, Shoeb Nizamuddin, Manked, Abizer Nuruddin, Myatra, S.N., Divatia, J.V., Kelkar, R., Biswas, S.K., Raut, V., Sampat, S., Thool, Alka, Karlekar, Anil, Nandwani, Sumi, Gupta, Sudhir, Singhal, Sanjay, Gupta, Madhu, Mathur, Purva, Kumar, Subodh, Sandhu, Kavita, Dasgupta, Arnab, Raha, Abhijeet, Raman, Padmalatha, Wadhera, Ashoo, Badyal, Binesh, Juneja, Sarika, Mishra, Bikas, Sharma, Sunil, Mehrotra, Megha, Shelgaonkar, Jayant, Padbidri, Vikram, Dhawale, Rohini, Sibin, Sheena Mary, Mane, Dileep, Sale, Hanamant Kashinath, Mukhit Abdul Gaffar Kazi, Mohammad, Chabukswar, Supriya, Mathew, Anju, Gaikwad, Dipti, Harshe, Amol, Nadimpalli, Gita, Bhamare, Sunil, Thorat, Soniya, Sarda, Omnarayan, Nadimpalli, Pattabhiramarao, Mendonca, Angelina, Malik, Sujata, Kamble, Asmita, Kumari, Nilakshi, Arora, Sohini, Munshi, Nita, Divekar, Deepa Ganesh, Kavathekar, Maithili Satish, Kulkarni, Anuja Kedar, Suryawanshi, Madhupriya Vijay, Bommala, Madhavi Latha, Bilolikar, Anil, Joshi, Kashmira Limaye, Pamnani, Charulata, Wasan, Harvinder, Khamkar, Sonali, Steephen, Leena, Rajalakshmi, Arjun, Thair, Anzar, Mubarak, Aisha, Sathish, Swathy, Kumar, Suresh, Sunil, H., Sujith, Sujith, Dinesh, Sen, Nagamani, Shinde, Nitin, Alebouyeh, Masoud, Jahani-Sherafat, Somayeh, Zali, Mohammad Reza, Sarbazi, Mohammad Reza, Mansouri, Nahid, Tajeddin, Elahe, Razaghi, Maryam, Seyedjavadi, Simasadat, Rashidan, Marjan, Masjedi, Mansoor, Maghsudi, Behzad, Sabetian, Golnar, Sanaei, Anahita, Yousefipour, Atefeh, Assiri, Abdullah Mufareh, Furukawa-Cinquini, Elaine Mari, Alshehri, Areej Dhafer, Giani, Alysia Faye, Demaisip, Nadia Lynette, Cortez, Elizabeth Laungayan, Cabato, Analen Fabros, Gonzales Celiz, Jerlie Mae, Al-Zaydani Asiri, Ibrahim A.M., Mohammed, Yassir Khidir, Abdullah Al Raey, Mohammed, Omer Abdul Aziz, Ali, Ali Al Darani, Saeed, Aziz, Misbah Rehman, Basri, Roaa Hasan, Al-Awadi, Duaa Khalil, Bukhari, Syed Zahid, Aromin, Rosita Gasmin, Ubalde, Evangelina Balon, Molano, Apsia Musa, Abdullah Al Enizy, Hessa, Baldonado, Celia Flores, Al Adwani, Fatima Mohammad, Marie Casuyon Pahilanga, Arlu, Tan, Avigail M., Joseph, Sonia, Nair, Deepa Sasidharan, Al-Abdullah, Nabeela Abdullah, Sindayen, Grace, Malificio, Annalyn Amor, Mohammed, Diaa Abdullah, Mesfer Al Ghamdi, Hanan, Silo, Ameurfina Curioso, Valisto, Marianina Brenda V., Foteinakis, Nektarios, Ghazal, Sameeh Salem, Joseph, Mercy V., Hakawi, Ahmed, Hasani, Antigona, Jusufi, Ismet, Spahija, Gazmend, Baftiu, Nehat, Gecaj-Gashi, Agreta, Aly, Nasser Yehia, El-Dossoky Noweir, Mohammad, Varghese, Suga Thomas, Ramapurath, Ruby Jose, Mohamed, Amna Mostafa, George, Sneha Mary, Kurian, Anu, Sayed, Amani Fouad, Salama, Mona Foda, Omar, Abeer Aly, Rebello, Flavie Maria, Narciso, Dennis Malungcot, Zahreddine, Nada Kara, Kanafani, Zeina, Kardas, Tala, Molaeb, Bassel, Jurdi, Lamia, Al Souheil, Anwar, Ftouni, Mohamad, Ayash, Hasan, Mahfouz, Tahsine, Kondratas, Tomas, Grinkeviciute, Dovile, Kevalas, Rimantas, Gailiene, Greta, Dagys, Algirdas, Petrovska, Milena, Popovska, Katja, Bogoevska-Miteva, Zaneta, Jankovska, Katerina, Guroska, Snezana Tufekcievska, Anguseva, Tanja, Wan Yusoff, Wan Nurbayah, Shiham Zainal Abidin, Anis, Gan, Chin Seng, Zainol, Hasimah, Rai, Vineya, Kwong, Wong Kang, Hasan, Mohd Shahnaz, Sri La Sri Ponnampala, Sasheela, Veerakumaran, Jeyaganesh, Assadian, Ojan, Phuong, Doan Mai, Binh, Nguyen Gia, Kaur, Kerinjeet, Lim, Joelene, Tan, Lian-Huat, Manikavasagam, Jegathesan, Cheong, Yuet-Meng, Magaña, Hilario Coronado, Cesar Mijangos Méndez, Julio, Jiménez, Federico Corona, Esparza-Ahumada, Sergio, Morfin-Otero, Rayo, Rodriguez-Noriega, Eduardo, Gutierrez-Martinez, Susana, Perez-Gomez, Hector Raul, León-Garnica, Gerardo, Mendoza-Mujica, Christian, Cecilia Culebro Burguet, Martha, Portillo-Gallo, Jorge Horacio, Almazán, Fernando Aguilera, Miramontes, Gaspar Iglesias, Olivas, Maria del Rosario Vázquez, Aguilar Angel, Lucio Alberto, Vargas, Marisol Sanchez, Orlando Flores Alvarado, Angel, Carlos Mares Morales, Roberto, Carlos Fernandez Alvarez, Luis, Armando Rincon Leon, Hector, Navarro Fuentes, Karla Reyna, Mariela Perez Hernandez, Yuri, Falcon, Gabriela Martinez, Vargas, Angel Gonzalez, Trujillo Juarez, Marco A., Mulia, Antonio Martinez, Alma Ulloa Camacho, Paulina, Martinez-Marroquin, Martha Y., Garcia, Marco Montell, Martinez, Araceli Martinez, Sanchez, Elena Leon, Flores, Guadalupe Gomez, Martínez, Marisela del Rocío González, Alfonso Galindo Olmeda, Jesús, Olivarez, Georgina, Rodriguez, Enrique Barbachano, Magdalena Gutierrez Castillo, María, Guadalupe Villa González, María, Beatriz Sauceda Castañeda, Isaura, Rodriguez, Jaime Martínez, Baatar, Otgon, Batkhuu, Byambadorj, Meryem, Kabiri, Amina, Barkat, Abouqal, Rédouane, Zeggwagh, Amine Ali, Dendane, Tarek, Abidi, Khalid, Madani, Naoufel, Mahmood, Syed Faisal, Memon, Badaruddin A., Bhutto, Gul Hassan, Paul, Nadeem, Parveen, Azra, Raza, Aun, Mahboob, Amjad, Nizamuddin, Summiya, Sultan, Faisal, Nazeer, Hammad, Khan, Ashraf Ali, Hafeez, Arifa, Lara, Lydia, Mapp, Trudell, Alvarez, Balkys, Rojas-Bonilla, Magda Ivonne, Castano, Elizabeth, De Moros, Daisy A., Atarama, Roberto Espinoza, Calisto Pazos, Maria Elena, Paucar, Alfredo, Ramos, Marlene Tasayco, Jurado, Jenny, Moreno, Dafne, Cruz Saldarriaga, Marãa E., Ramirez, Eliza, La Hoz Vergara, Carlos Enrique, Enrique Prudencio Leon, Walter, Isidro Castillo Bravo, Luis, Fernanda Aibar Yaranga, Katya, Pichilingue Chagray, Janet E., Marquez Mondalgo, Vanessa A., Zegarra, Socorro Torres, Astete, Nazario Silva, Guevara, Francisco Campos, Pastrana, Javier Soto, Linares Calderon, Carlos F., Jesus Mayorga Espichan, Manuel, Martin Santivanez Monge, Luis, Changano Rodriguez, Maria V., Rosa Diaz Tavera, Zoila, Martin Ramirez Wong, Fernando, Chavez, Selene Manga, Atencio-Espinoza, Teodora, Villanueva, Victoria D., Blanco-Abuy, Maria Teresa, Tamayo, Arnefelina S., Bergosa, Lailane D., Llames, Cristina Mari Jean P., Trajano, Marilou F., Bunsay, Suzette A., Amor, Jessica C., Berba, Regina, Sg Buenaflor, Maria Carmen, Labro, Ever, Mendoza, Myrna T., Javellana, Ofelia P., Salvio, Lilibeth G., Rayco, Rhoda Gay, Bermudez, Vanessa, Kubler, Andrzej, Zielinska, Marzena, Kosmider-Zurawska, Magdalena, Barteczko-Grajek, Barbara, Szewczyk, Ewa, Dragan, Barbara, Mikaszewska-Sokolewicz, Malgorzata Anna, Lazowski, Tomasz, Cancel, Elsie, Licker, Monica Sorina, Dragomirescu, Liliana Alina, Dumitrascu, Victor, Sandesc, Dorel, Bedreag, Ovidiu, Papurica, Marius, Muntean, Delia, Kotkov, Igor, Kretov, Vladimir, Shalapuda, Vladimir, Molkov, Alexander, Puzanov, Sergey, Utkin, Ivan, Tchekulaev, Alexander, Tulupova, Valentina, Nikolic, Ljubica, Ristic, Goran, Eremija, Jelena, Kojovic, Jelena, Lekic, Dragana, Vasiljevic, Sladjana, Lesnakova, Anna, Marcekova, Alzbeta, Furova, Katarina, Gamar Elanbya, May Osman, Ali, Malik Abdo, Kadankunnel, Shobhana Kumari, Somabutr, Suwara, Pimathai, Rungratchanee, Wanitanukool, Suthinee, Luxsuwong, Montri, Supa, Namphon, Prasan, Pornpheth, Thamlikitkul, Visanu, Jamulitrat, Silom, Suwalak, Nonglak, Phainuphong, Parichart, Asma, Bouziri, Aida, Borgi, Sarra, Bel Hadj, Ammar, Khaldi, Ertem, Gunay Tuncer, Bulut, Cemal, Hatipoglu, Cigdem Ataman, Erdinc, Fatma Sebnem, Demiroz, Ali Pekcan, Ozcelik, Menekse, Meco, Basak Ceyda, Oral, Mehmet, Unal, Necmettin, Guclu, Cigdem Yildirim, Kendirli, Tanıl, İnce, Erdal, Çiftçi, Ergin, Yaman, Ayhan, Ödek, Çağlar, Karbuz, Adem, Kocabaş, Bilge Aldemir, Altın, Nilgün, Cesur, Salih, Atasay, Begum, Erdeve, Omer, Akduman, Hasan, Kahvecioglu, Dilek, Cakir, Ufuk, Yildiz, Duran, Kilic, Atila, Arsan, Saadet, Arman, Dilek, Unal, Serhat, Gelebek, Yasemin, Zengin, Humeyra, Sen, Suha, Cabadak, Hatice, Erbay, Ayse, Yalcin, Ata Nevzat, Turhan, Ozge, Cengiz, Melike, Dursun, Oguz, Gunasan, Perihan, Kaya, Sehnaz, Ramazanoglu, Atilla, Ustun, Cemal, Yasayacak, Aliye, Akdeniz, Hayrettin, Sirmatel, Fatma, Otkun, Ali Metin, Sacar, Suzan, Sener, Alper, Turgut, Huseyn, Sungurtekin, Hulya, Ugurcan, Dogaç, Necan, Ceyda, Yilmaz, Cansu, Ozdemir, Davut, Geyik, Mehmet Faruk, Ince, Nevin, Danis, Ayse, Erdogan, Selvi Yener, Erben, Nurettin, Usluer, Gaye, Ozgunes, Ilhan, Uzun, Cengiz, Oncul, Oral, Gorenek, Levent, Erdem, Hakan, Baylan, Orhan, Ozgultekin, Asu, Inan, Asuman, Bolukcu, Sibel, Senol, Gunes, Ozdemir, Halil, Gokmen, Zeynel, Ozdemir, Sonay Incesoy, Kaya, Ali, Ersoz, Gulden, Kuyucu, Necdet, Karacorlu, Sevim, Kaya, Zeynep, Guclu, Ertugrul, Kaya, Gulsume, Karabay, Oguz, Esen, Saban, Aygun, Canan, Ulger, Fatma, Dilek, Ahmet, Yilmaz, Hava, Sunbul, Mustafa, Engin, Aynur, Bakir, Mehmet, Elaldi, Nazif, Koksal, Iftihar, Yildizdas, Dincer, Horoz, Ozden Ozgur, Willke, Ayşe, Koç, Meliha Meriç, Azak, Emel, Elahi, Naheed, Annamma, Philip, El Houfi, Ashraf, Pirez Garcia, Maria Catalina, Vidal, Hector, Perez, Fernando, Empaire, Gabriel D., Ruiz, Yvis, Hernandez, Dulce, Aponte, Dayana, Salinas, Evelyn, Diaz, Claudia, Guzmán Siritt, María Eugenia, Gil De Añez, Zenaida Durán, Bravo, Luis Montes, Orozco, Nelva, Mejías, Eugenia, Hung, Nguyen Viet, Anh, Nguyen Quoc, Chau, Ngo Quy, Thu, Truong Anh, Thi Diem Tuyet, Le, Thi Van Trang, Dang, Hong Thoa, Vo Thi, Tien, Nguyen Phuc, Anh Thu, Le Thi, Hang, Phan Thi, My Hanh, Tran Thi, Thuy Hang, Tran Thi, Phuong Anh, Dinh Pham, Rosenthal, Víctor Daniel, Maki, Dennis George, Mehta, Yatin, Leblebicioglu, Hakan, Memish, Ziad Ahmed, Al-Mousa, Haifaa Hassan, Balkhy, Hanan, Hu, Bijie, Alvarez-Moreno, Carlos, Medeiros, Eduardo Alexandrino, Apisarnthanarak, Anucha, Raka, Lul, Cuellar, Luis E., Ahmed, Altaf, Navoa-Ng, Josephine Anne, El-Kholy, Amani Ali, Kanj, Souha Sami, Bat-Erdene, Ider, Duszynska, Wieslawa, Van Truong, Nguyen, Pazmino, Leonardo N., See-Lum, Lucy Chai, Fernández-Hidalgo, Rosalia, Di-Silvestre, Gabriela, Zand, Farid, Hlinkova, Sona, Belskiy, Vladislav, Al-Rahma, Hussain, Luque-Torres, Marco Tulio, Bayraktar, Nesil, Mitrev, Zan, Gurskis, Vaidotas, Fisher, Dale, Abu-Khader, Ilham Bulos, Berechid, Kamal, Rodríguez-Sánchez, Arnaldo, Horhat, Florin George, Requejo-Pino, Osiel, Ben-Jaballah, Nejla, García-Mayorca, Elías, Kushner-Dávalos, Luis, Pasic, Srdjan, Pedrozo-Ortiz, Luis E., Apostolopoulou, Eleni, Mejía, Nepomuceno, Gamar-Elanbya, May Osman, Jayatilleke, Kushlani, de Lourdes-Dueñas, Miriam, and Aguirre-Avalos, Guadalupe

Published
2014
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29. Algebraic concordance order of almost classical knots.

Author

Chrisman, Micah and Mukherjee, Sujoy

Subjects
*ABELIAN groups, *NONABELIAN groups, *TORSION
Abstract

Torsion in the concordance group of knots in S 3 can be studied with the algebraic concordance group . Here, is a field of characteristic χ () ≠ 2. The group was defined by Levine, who also obtained an algebraic classification when = ℚ. While the concordance group is abelian, it embeds into the non-abelian virtual knot concordance group . It is unknown if admits non-classical finite torsion. Here, we define the virtual algebraic concordance group for Seifert surfaces of almost classical knots. This is an analogue of for homologically trivial knots in thickened surfaces Σ × [ 0 , 1 ] , where Σ is closed and oriented. The main result is an algebraic classification of . A consequence of the classification is that ℚ embeds into ℚ and ℚ contains many nontrivial finite-order elements that are not algebraically concordant to any classical Seifert matrix. For = ℤ / 2 ℤ , we give a generalization of the Arf invariant. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Hyperbolic Knots and Torsion in Khovanov Homology

Author

Chrisman, Micah and Mukherjee, Sujoy

Subjects
Mathematics - Geometric Topology, Mathematics::K-Theory and Homology, Mathematics::Quantum Algebra, FOS: Mathematics, Mathematics::Metric Geometry, Geometric Topology (math.GT), Mathematics::Symplectic Geometry, Mathematics::Geometric Topology, 57K18, 57K32, 57K10
Abstract

In this note, we show that if there is a knot in $S^3$ having $\mathbb{Z}_m$ torsion in its Khovanov homology, then there are infinitely many hyperbolic knots and infinitely many prime satellite knots having $\mathbb{Z}_m$ torsion in their Khovanov homology. As an application, we give the first known examples of hyperbolic knots and links with odd (and other non-$\mathbb{Z}_2$ torsion) in their Khovanov homology., 10 pages, 8 figures. Comments welcome. v2-typo corrected in ArXiv metadata. No change to paper

Published
2022

33. 'Microincisional trabeculectomy for glaucoma".

Author

Rao, Aparna, Khan, Sardar, and Mukherjee, Sujoy

Subjects
TRABECULECTOMY, OPTICAL coherence tomography, OPEN-angle glaucoma, GLAUCOMA, CATARACT surgery
Abstract

Purpose: To evaluate the short-term clinical outcomes of microincisional trabeculectomy (MIT), a new technique of ab-interno trabeculectomy. Methods: Consecutive patients with open-angle glaucoma identified from the hospital database that underwent MIT with or without cataract surgery between September 2021 to June 2022 at a tertiary eye centre in East India, were screened. Those with a follow-up of < 6 months or with incomplete data were excluded. MIT was done ab-interno using microscissors and microforceps in 2–4 clock hours of the nasal angle via a temporal incision. The intraocular pressure (IOP) reduction at 6 months, and reduction in the number of medications after surgery were analysed. Surgical success (IOP>6 and <22 mm Hg), complications, angle features on anterior segment optical coherence tomography (ASOCT), and the need for additional surgeries were analysed. Results: We included thirty-two eyes of 32 patients with open-angle glaucoma (including n = 9 eyes that underwent concurrent cataract surgery) with a preoperative mean IOP of 22 ±11.1 mm Hg and visual field index of 47±37.9%. All eyes achieved >30% IOP reduction, with a final IOP of 14±6.9 mm Hg at 6 months. Surgical success in 31 of 32 eyes with complete success seen in 28 eyes with none of the eyes requiring >1 medication for IOP control. Hyphema was seen in 4 eyes, while transient IOP spikes at 1 day-1 month were seen in 5 eyes, none of which required any additional interventions. One eye with persistent raised IOP at 1 month required incisional trabeculectomy for uncontrolled IOP with 2 medications. Conclusion: MIT, a new technique of ab-interno trabeculectomy, is effective in terms of IOP control and reduction in the number of medications while having fewer complications. Long-term studies comparing the efficacy of MIT with incisional trabeculectomy, or other procedures are warranted in the future. [ABSTRACT FROM AUTHOR]

Published
2023
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40. Causes of Immediate and Early IOP Spikes After Circumferential Gonioscopy-Assisted Transluminal Trabeculotomy Using ASOCT.

Author

Rao, Aparna, Khan, Sardar Mohd, and Mukherjee, Sujoy

Subjects
TRABECULECTOMY, IRIS (Eye), INTRAOCULAR pressure, OPTICAL coherence tomography, EYE care
Abstract

Purpose: To report the early postoperative causes of intraocular pressure (IOP) spikes after complete circumferential gonioscopy-assisted transluminal trabeculotomy (GATT) using anterior segment optical coherence tomography (ASOCT). Methods: This was retrospective interventional case series of patients who underwent circumferential GATT by a single surgeon (APR) from 2021 to 2022 at a tertiary eye care in East India and who developed IOP spikes at 1 day-2 weeks (immediate) or early (> 2 weeks– 2 months) after GATT. The intraocular pressure (IOP), glaucoma medications, and angle evaluation by ASOCT at 1 week, and 1 month were compared between the two groups. Results: Thirty-two eyes of 32 consecutive patients, aged 40± 20.1 years (20 exfoliation glaucoma, 9 juvenile open-angle, and 3 developmental glaucoma), that developed IOP spikes between immediate (n=20) or early (n=12) IOP spikes after GATT, were included. Immediate postoperative spikes were seen in 20 eyes due to retained viscoelastic (n=8), hyphema (n=8) in uncontrolled hypertension, and peripheral anterior synechiae (PAS) (n=6) of which only one eye required medication at 2 months. Causes of immediate IOP spikes on ASOCT included an inverted/reattached trabecular shelf, iris strands in eyes with abnormal iris in developmental glaucoma, and PAS in 1– 2 quadrants. Causes of early IOP spikes included PAS > 3 quadrants (n=8), and hyperreflective fibrotic tissue over TM (n=4) with 50% requiring medications at 2 months. The ASOCT features predicting the need for medications were PAS > 3 quadrants (OR=8.4[2.2– 14.3], p=0.03) and fibrotic TM closure (OR=5.4, [3.6– 10.2], p=0.003). One eye with macrohyphema 3 days after surgery owing to uncontrolled hypertension (owing to the stoppage of medicines), required additional incisional trabeculectomy within 1 month of surgery. Conclusion: Immediate IOP spikes are mostly self-resolving as opposed to early IOP spikes > 2 weeks that require medications after GATT. Gonioscopic PAS > 3 quadrants, and fibrotic TM closure were the main identifiable ASOCT causes predicting the need for medications after GATT. [ABSTRACT FROM AUTHOR]

Published
2023
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41. Algebraic concordance order of almost classical knots

Author

Chrisman, Micah and Mukherjee, Sujoy

Subjects
Mathematics - Geometric Topology, 57K12, 57N70, FOS: Mathematics, Mathematics::General Topology, Geometric Topology (math.GT), Mathematics::Geometric Topology
Abstract

Torsion in the concordance group $\mathscr{C}$ of knots in $S^3$ can be studied with the algebraic concordance group $\mathscr{G}^{\mathbb{F}}$. Here $\mathbb{F}$ is a field of characteristic $\chi(\mathbb{F}) \ne 2$. The group $\mathscr{G}^{\mathbb{F}}$ was defined by J. Levine, who also obtained an algebraic classification when $\mathbb{F}=\mathbb{Q}$. While the concordance group $\mathscr{C}$ is abelian, it embeds into the non-abelian virtual knot concordance group $\mathscr{VC}$. It is unknown if $\mathscr{VC}$ admits non-classical finite torsion. Here we define the virtual algebraic concordance group $\mathscr{VG}^{\mathbb{F}}$ for almost classical knots . This is an analogue of $\mathscr{G}^{\mathbb{F}}$ for homologically trivial knots in thickened surfaces $\Sigma \times [0,1]$, where $\Sigma$ is closed and oriented. The main result is an algebraic classification of $\mathscr{VG}^{\mathbb{F}}$. A consequence of the classification is that $\mathscr{G}^{\mathbb{Q}}$ embeds into $\mathscr{VG}^{\mathbb{Q}}$ and $\mathscr{VG}^{\mathbb{Q}}$ contains many nontrivial finite-order elements that are not algebraically concordant to any classical Seifert matrix. For $\mathbb{F}=\mathbb{Z}/2\mathbb{Z}$, we give a generalization of the Arf invariant., Comment: 38 pages, 11 figures. v2-24 pages. Minor title change. Reorganized and shortened exposition. Some results in Section 3 and 5 removed to be placed in separate papers. Typos fixed along with other minor corrections

Published
2021

43. NMR investigations of the static and dynamic structures of bisphosphonates on human bone: a molecular model

Author

Mukherjee, Sujoy, Yongcheng Song, and Oldfield, Eric

Subjects
Nuclear magnetic resonance spectroscopy -- Usage, Phosphonates -- Research, Phosphonates -- Chemical properties, Chemical bonds -- Research, Chemistry
Abstract

Nuclear magnetic resonance spectroscopy is used for examining the binding of a series of bisphosphonate drugs to human bone. The results have shown that the N[H.sub.3.sup.+]-terminus of pamidronate is close to the bone mineral surface and a model is proposed in which the gauche side-chain hops between two bone P[O.sub.4.sup.3-] sites.

Published
2008

45. Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes

Author

Junhong Mao, Mukkamala, Dushyant, Mukherjee, Sujoy, Yong Zhang, Yi Gui Gao, Hudock, Michael P., Meints, Gary A., Oldfield, Eric, Rong Cao, Yongui Zhang, Sanders, John M., and Yongcheng Song

Subjects
Nuclear magnetic resonance -- Usage, Diphosphonates -- Chemical properties, Diphosphonates -- Structure, Quantum theory -- Research, Chemistry
Abstract

The results of a solid-state [super 13]C, [super 15]N, and [super 31]P magic-angle sample spinning (MAS) NMR and quantum chemical investigation of several bisphosphonates, both as pure compounds and when bound to farnesyl diphosphate synthase (FPPS) is reported. Bisphosphonates are a class of molecules in widespread use in treating bone resorption diseases and are also of interest as immunomodulators and anti-infectives.

Published
2006

47. On multiplying curves in the Kauffman bracket skein algebra of the thickened four-holed sphere.

Author

Bakshi, Rhea Palak, Mukherjee, Sujoy, Przytycki, Józef H., Silvero, Marithania, and Wang, Xiao

Subjects
*ALGEBRA, *TORUS, *LOGICAL prediction, *ALGORITHMS
Abstract

Based on the presentation of the Kauffman bracket skein algebra of the thickened torus given by the third author in previous work [4], Frohman and Gelca established a complete description of the multiplicative operation leading to a famous product-to-sum formula. In this paper, we study the multiplicative structure of the Kauffman bracket skein algebra of the thickened four-holed sphere. We present an algorithm to compute the product of any two elements of the algebra, and give an explicit formula for some families of curves. We surmise that the algorithm has quasi-polynomial growth with respect to the number of crossings of a pair of curves. Further, we conjecture the existence of a positive basis for the algebra. [ABSTRACT FROM AUTHOR]

Published
2021
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48. Homology of Associative Shelves

Author

Crans, Alissa S., Mukherjee, Sujoy, and Przytycki, J��zef H.

Subjects
Mathematics - Geometric Topology, FOS: Mathematics, Geometric Topology (math.GT), Mathematics::Algebraic Topology, Mathematics::Geometric Topology, Primary: 18G60, Secondary: 20M32, 20N02, 57M25
Abstract

Homology theories for associative algebraic structures are well established and have been studied for a long time. More recently, homology theories for self-distributive algebraic structures motivated by knot theory, such as quandles and their relatives, have been developed and investigated. In this paper, we study associative self-distributive algebraic structures and their one-term and two-term (rack) homology groups., 18 pages, 3 figures

Published
2016

49. Thermodynamics of bisphosphonates binding to human bone: a two-site model

Author

Mukherjee, Sujoy, Huang, Cancan, Guerra, Franciso, Ke Wang, and Oldfield, Eric

Subjects
Bones -- Physiological aspects, Bones -- Structure, Calorimetry -- Usage, Diphosphonates -- Chemical properties, Diphosphonates -- Thermal properties, Linear models (Statistics) -- Usage, Linear regression models -- Usage, Protein binding -- Analysis, Chemistry
Abstract

Isothermal titration calorimetry (ITC) is used for studying the thermodynamics of binding of 12 biphosphonates to human bone. The thermodynamic group approach and a linear regression method are used for predicting the [DELTA]G of binding of all 12 compounds, opening a way to designing novel chemotherapy, immunotherapy and anti-infectious disease drugs having weak bone binding affinity.

Published
2009

50. Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation

Author

Yonghui Zhang, Rong Cao, Fenglin Yin, Hudock, Michael P., Rey-Ting Guo, Krysiak, Kilannin, Mukherjee, Sujoy, Yi-Gui Gao, Robinson, Howard, Yongcheng Song, Joo Hwan No, Bergan, Kyle, Leon, Annette, Cass, Lauren, Goddard, Amanda, Ting-Kai Chang, Van Beek, Ermond, Papapoulos, Socrates, Wang, Andrew H.-J., Kubo, Tadahiko, Ochi, Mitsuo, Mukkamala, Dushyant, Fu-Yang Lin, and Oldfield, Eric

Subjects
Antimitotic agents -- Chemical properties, Antimitotic agents -- Structure, Antineoplastic agents -- Chemical properties, Antineoplastic agents -- Structure, Calorimetry -- Usage, Diphosphonates -- Chemical properties, Diphosphonates -- Structure, Nuclear magnetic resonance spectroscopy -- Usage, X-rays -- Diffraction, X-rays -- Usage, Chemistry
Abstract

A new strategy is described for anticancer therapeutic agents involving inhibition of farnesyl diphosphate synthase (FPPS) and geranylgeranyl diphosphate synthase (GGPPS), the two enzymes upstream of farnesyl transferase (FTase) and geranylgeranyl transferase (GGTase), by lipophilic bisphosphonates. X-ray diffraction, solid-state NMR and isothermal titration calorimetry are used for exploring how these compounds have inhibited cell growth and how cell activity is predicted based on enzyme inhibition data.

Published
2009

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