Search

Your search keyword '"Montagne, Lucile"' showing total 97 results
Start Over Author "Montagne, Lucile" Language english
97 results on '"Montagne, Lucile"'

5. The PPILOW project: Innovations improving welfare in low input and organic pig and poultry farms

Author

Collin, Anne, Meloni, Giuditta, Bonnefous, Claire, Re, Martina, van Vooren, Laura, Niemi, Jarkko, Väre, Minna, Lähtinen, Katja, Tuyttens, Frank A.M., Graat, Evelien, Vanden Hole, Charlotte, Rodenburg, Tb (bas), Kliphuis, Saskia, Giersberg, Mona, Tavares, Olivia, Desaint, Brieuc, Steenfeldt, Sanna, Pedersen, Lene, Engberg, Ricarda M., Almadani Mohamad, Isam, Carelli, Riccardo, Sciarretta, Marlene, Guilloteau, Laurence, Réhault-Godbert, Sophie, Gautron, Joël, Le Bihan-Duval, Elisabeth, Mignon-Grasteau, Sandrine, Berri, Cécile, Guettier, Elodie, Baéza, Elisabeth, Chartrin, Pascal, Bordeau, Thierry, Raynaud, Emilie, Couroussé, Nathalie, Cailleau-Audouin, Estelle, Crochet, Sabine, Tourneur, Léa, Guichaoua, Adrien, van den Brand, Henry, Castellini, Cesare, Reverchon, Maxime, Sourdioux, Michel, Akakpo, Roland, Rangel Pedersen, Ninfa, Schepens, Rene, Almind, Maria, Grenier, Katia, Dubuc, David, Le Lann, Marie-Véronique, Ponzio, Raffaella, Mainardi, Marina, Accotto, Caterina, Coletta, Monica, Guesdon, Vanessa, Leruste, Hélène, Billiard, Bérangère, Ferreira, Vitor Hugo Bessa, Baldinger, Lisa, Pluschke, Helen, Delanoue, Elsa, Laura, Warin, Pertusa, Marion, Stomp, Mathilde, Travel, Angelique, Bouvarel, Isabelle, Germain, Karine, Ravon, Laure, Calandreau, Ludovic, Labas, Valérie, Prunier, Armelle, Merlot, Elodie, Tallet, Céline, Perruchot, Marie-Hélène, Louveau, Isabelle, van Milgen, Jaap, Dessauge, Frederic, Clouard, Caroline, Lebret, Bénédicte, Montagne, Lucile, Faure, Justine, Zuliani, Anna, Venezia, Pietro, Canario, Laurianne, Ferchaud, Stéphane, Cozma, Vasile, Spinu, Marina, Horia Bǎieş, Mihai, Courboulay, Valérie, Roguet, Christine, Gaudré, Didier, Chevillon, Patrick, Alibert, Laurent, Decruyenaere, Virginie, Wavreille, José, Vanggaard, Pia, Vanggaard, Jan, Micheloni, Cristina, Thobe, Petra, Lombard, Sarah, Caillaud, Laura, Bernardet, Nelly, Collet, Julie, Molenaar, Roos, Mattioli, Simona, Hill, Nigel, Cadudal, François, Quentin, Maxime, Leterrier, Christine, Teixeira-Gomes, Ana-Paula, Uzbekova, Svetlana, Maugrion, Emilie, Rocchi, Lucia, Biologie des Oiseaux et Aviculture (BOA), Université de Tours (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Università degli Studi di Perugia = University of Perugia (UNIPG), Associazione Italiana per l'Agricoltura Biologica (AIAB), Scuela Santa Anna (SSSA), Scuola Universitaria Superiore Sant'Anna [Pisa] (SSSUP), BioForum Vlaanderen, Natural Resources Institute Finland (LUKE), Research Institute for Agricultural, Fisheries and Food (ILVO), Utrecht University [Utrecht], Institut Technique de l'Agriculture Biologique (ITAB), Aarhus University [Aarhus], Thuenen Institute of Farm Economics, European Association for Animal Production (EAAP), Les instituts techniques agricoles (Acta), Wageningen University and Research [Wageningen] (WUR), Syndicat des Sélectionneurs Avicoles et Aquacoles Français (SYSAAF), Fermentation Experts, Équipe Micro et nanosystèmes HyperFréquences Fluidiques (LAAS-MH2F), Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Équipe DIagnostic, Supervision et COnduite (LAAS-DISCO), Slow Food Biodiversity, JUNIA (JUNIA), Université catholique de Lille (UCL), Thuenen-Institute of Organic Farming, ITAVI, Elevage Alternatif et Santé des Monogastriques (UE EASM), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut Français du Cheval et de l'Equitation [Saumur] (IFCE)-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), SIVtro VSF Italia, Génétique Physiologie et Systèmes d'Elevage (GenPhySE ), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-École nationale supérieure agronomique de Toulouse (ENSAT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité Expérimentale Elevages Porcins Innovants (GenESI), USAMV Cluj-Napoca, Institut du Porc (IFIP), Centre Wallon de Recherches Agronomiques (CRA-W), Vanggaard Staldmontage, Harper Adams University, EAAP, PPILOW, and European Project: 816172,H2020-EU.3.2.1.1. - Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience ,PPILOW (2019)

Subjects
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences, [SCCO]Cognitive science, [SDV.GEN]Life Sciences [q-bio]/Genetics, [SDV.BA]Life Sciences [q-bio]/Animal biology, [SDV.BDD]Life Sciences [q-bio]/Development Biology, [SHS]Humanities and Social Sciences
Abstract

International audience; The PPILOW project aims to co-construct innovations to improve Poultry and Pig Welfare in Low-input outdoor and Organic farming systems through a multi-actor approach. PPILOW implements a participatory approach for proposing and studying welfare-improvement levers. It will provide a combination of practical solutions that can be applied at a pan-European level with specific adjustments depending on citizen’s expectations and the target market. The multi-actor approach consists in involving end-users including farmers, breeding companies, feed producers, consumer associations, retailers, advisers, processors, and scientists in National Practitioner Groups (NPG) in six participating countries. PPILOW partners facilitate the groups by connecting NPG at European level, transferring scientific information, interacting with partners engaged in animal experiments, and co-creating innovations rising from NPG-specific demands. They co-build with PPILOW partners welfare self-assessment tools (development of the PIGLOW app for pigs and refinement of the EBENE® app for poultry), and innovative breeding, feeding, and rearing strategies and techniques to improve the welfare of animals. They co-design protocols, test innovations on farm, and disseminate the results. In turn, they receive insights on methods and scientific results, and inputs from other NPG reinforcing the value of the expected outcomes. Approaches focus on avoiding physical damage and the elimination of layer male chicks, on reducing boar taint of intact male pigs, promoting positive behaviours, animal health, and robustness through field studies with pigs and poultry. Multicriteria analyses of the most effective levers of welfare improvement will be performed to evaluate their economic, social, and environmental impacts based on the ‘One Welfare’ concept; economic and business models will also be developed. To ensure the rapid uptake of the project results by end-users, the close involvement of PPILOW’s NPG throughout the EU will ensure disseminationactivities and the facilitation of change. The PPILOW project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under grant agreement N°816172. www.ppilow.eu.

Published
2022

8. Organic pig and poultry production: what are the animal welfare challenges?

Author

Bonnefous, Claire, Collin, Anne, Niemi, Jarkko, Väre, Minna, Parrott, Patricia, Walley, Keith, Re, Martina, Ponzio, Raffaella, Rodenburg, T. Bas, Tallet, Céline, Merlot, Elodie, Montagne, Lucile, Faure, Justine, Guilloteau, Laurence, Guesdon, Vanessa, Leruste, Hélène, Delanoue, Elsa, Alibert, Laurent, Roinsard, Antoine, Warin, Laura, Leterrier, Christine, Biologie des Oiseaux et Aviculture (BOA), Université de Tours (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Natural Resources Institute Finland (LUKE), Harper Adams University, Associazione Italiana per l'Agricoltura Biologica (AIAB), Scuela Santa Anna (SSSA), Scuola Universitaria Superiore Sant'Anna [Pisa] (SSSUP), Slow Food Biodiversity, Utrecht University [Utrecht], Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Rennes Angers, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut Français du Cheval et de l'Equitation [Saumur] (IFCE)-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), JUNIA (JUNIA), Université catholique de Lille (UCL), Institut de l'élevage (IDELE), Institut du Porc (IFIP), Institut Technique de l'Agriculture Biologique (ITAB), ITAVI, This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 816172, and European Project: 816172,H2020-EU.3.2.1.1. - Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience ,PPILOW (2019)

Subjects
[SCCO]Cognitive science, [SHS.SOCIO]Humanities and Social Sciences/Sociology, [SDV]Life Sciences [q-bio], Animal husbandry, Farming Systems
Abstract

International audience; Although organic animal production is based on farming systems that enable a high degree of expression of natural behaviour by the animals, there are still some welfare challenges in such systems. Our study provides a state of the art of practices that could improve animal welfare in organic productions and interviews with key informants have been conducted to identify gaps and opportunities for animal welfare. This study provides a shortlist of practices that could be used to improve animal welfare while taking into account farmer wellbeing and sustainability and so contributing to “One Welfare”.

Published
2021

9. The multi-actor PPILOW European project: a participative approach to co-build innovations for welfare improvement in organic pig and poultry farms

Author

Micheloni, Cristina, Jamart, An, Re, Martina, van Vooren, Laura, Niemi, Jarkko, Tuyttens, Frank A.M., Rodenburg, Tb (bas), Roinsard, Antoine, Steenfeldt, Sanna, Thobe, Petra, Carelli, Riccardo, Sciarretta, Marlene, Bonnefous, Claire, Bodin, Pauline, Rosati, Andrea, van den Brand, Henry, Rocchi, Lucia, Reverchon, Maxime, Decruyenaere, Virginie, Wavreille, José, Grete, Brunsgaard, Depraetere, Stefaan, Grenier, Katia, Vanggaard, Jan, Ponzio, Raffaella, Guesdon, Vanessa, Leruste, Hélène, Walley, Keith, Cozma, Vasile, Le Bihan-Duval, Elisabeth, Engberg, Ricarda M., Réhault-Godbert, Sophie, Baldinger, Lisa, Thys, Mirjan, Prunier, Armelle, Merlot, Elodie, Tallet, Céline, Montagne, Lucile, Canario, Laurianne, Delanoue, Elsa, Courboulay, Valérie, Hercule, Jonathan, Leterrier, Christine, Latchoumia, Joselle, Laura, Warin, Collin, Anne, Associazione Italiana per l'Agricoltura Biologica (AIAB), BioForum Vlaanderen, Scuela Santa Anna (SSSA), Scuola Universitaria Superiore Sant'Anna [Pisa] (SSSUP), Natural Resources Institute Finland (LUKE), Research Institute for Agricultural, Fisheries and Food (ILVO), Utrecht University [Utrecht], Institut Technique de l'Agriculture Biologique (ITAB), Aarhus University [Aarhus], Thuenen Institute of Farm Economics, European Association for Animal Production (EAAP), Biologie des Oiseaux et Aviculture (BOA), Université de Tours (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Les instituts techniques agricoles (Acta), Wageningen University and Research [Wageningen] (WUR), Università degli Studi di Perugia = University of Perugia (UNIPG), Syndicat des Sélectionneurs Avicoles et Aquacoles Français (SYSAAF), Centre Wallon de Recherches Agronomiques (CRA-W), Fermentation Experts, Circular Organics, Équipe Micro et nanosystèmes HyperFréquences Fluidiques (LAAS-MH2F), Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Vanggaard Staldmontage, Slow Food Biodiversity, JUNIA (JUNIA), Université catholique de Lille (UCL), Harper Adams University, USAMV Cluj-Napoca, Thuenen-Institute of Organic Farming, Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Génétique Physiologie et Systèmes d'Elevage (GenPhySE ), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-École nationale supérieure agronomique de Toulouse (ENSAT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de l'élevage (IDELE), Institut du Porc (IFIP), ITAVI, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut Français du Cheval et de l'Equitation [Saumur] (IFCE)-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), INRAE Transfert, The PPILOW project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under grant agreement N°816172., IFOAM, PPILOW, and European Project: 816172,H2020-EU.3.2.1.1. - Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience ,PPILOW (2019)

Subjects
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences, [SDV.GEN]Life Sciences [q-bio]/Genetics, [SCCO]Cognitive science, [SDV.BA]Life Sciences [q-bio]/Animal biology, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.BDD]Life Sciences [q-bio]/Development Biology, ComputingMilieux_MISCELLANEOUS, [SHS]Humanities and Social Sciences
Abstract

International audience

Published
2021

10. One Welfare for farm animals and humans: practitioners’ and citizens’ expectations

Author

Collin, Anne, Bonnefous, Claire, Leterrier, Christine, Tallet, Céline, Merlot, Elodie, Montagne, Lucile, Walley, Keith, Parrott, Tricia, Allan, Shelley, Castellini, Cesare, Meloni, Giudita, Rocchi, Lucia, Thobe, Petra, Almadani Mohamad, Isam, Warin, Laura, Pertusa, Marion, Hercule, Jonathan, Roguet, Christine, Delanoue, Elsa, Re, Martina, Micheloni, Cristina, Coletta, Monica, Accotto, Caterina, van Vooren, Laura, Jamart, An, Ponzio, Raffaella, Zuliani, Anna, Venezia, Pietro, Herremans, Sophie, Decruyenaere, Virginie, Cozma, Vasile, Spinu, Marina, Tuyttens, Frank A.M., Thys, Mirjan, Graat, Evelien, Rodenburg, T Bas, Kliphuis, Saskia, Giersberg, Mona, Väre, Minna, Lähtinen, Katja, Heinola, Katriina, Niemi, Jarkko, Biologie des Oiseaux et Aviculture (BOA), Université de Tours (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut Français du Cheval et de l'Equitation [Saumur] (IFCE)-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Harper Adams University, Università degli Studi di Perugia = University of Perugia (UNIPG), Thuenen Institute of Farm Economics, ITAVI, Institut du Porc (IFIP), Institut de l'élevage (IDELE), Italian Association for Organic Agriculture (AIAB-FVG), Scuola Superiore Sant'Anna (SSSA), BioForum Vlaanderen, Slow Food Biodiversity, SIVtro VSF Italia, Centre Wallon de Recherches Agronomiques (CRA-W), USAMV Cluj-Napoca, USAMV cluj-Napoca, Research Institute for Agricultural, Fisheries and Food (ILVO), Utrecht University [Utrecht], Natural Resources Institute Finland (LUKE), European Union’s Horizon 2020 research and innovation programme under grant agreement No 816172, Joint Online Conference OK-Net EcoFeed, PPILOW, Freebirds and POWER EU Projects, and European Project: 816172,H2020-EU.3.2.1.1. - Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience ,PPILOW (2019)

Subjects
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences, [SDV.GEN]Life Sciences [q-bio]/Genetics, [SDV.BA]Life Sciences [q-bio]/Animal biology, [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.BDD]Life Sciences [q-bio]/Development Biology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021

11. Increasing digesta viscosity using carboxymethylcellulose in weaned piglets stimulates ileal goblet cell numbers and maturation

Author

Piel, Christelle, Montagne, Lucile, Seve, Bernard, and Lalles, Jean-Paul

Subjects
Mucins -- Health aspects, Intestines -- Obstructions, Intestines -- Diet therapy, Food/cooking/nutrition
Abstract

Intestinal mucin, a family of glycoproteins secreted by goblet cells, is the main constituent of the mucus protecting the gastrointestinal tract. For optimal mucosal protection, both the quantitative and qualitative characteristics of mucin are essential. To evaluate how viscosity influences ileal apparent digestibility and mucin biology, a highly viscous nonfermentable soluble polysaccharide, carboxymethylcellulose (CMC), was fed to weaned piglets for 15 d. The ileal crude mucin concentration was determined by ethanol precipitation, and changes in goblet cell subtypes were analyzed by the histochemistry of ileal and colonic tissues. As expected, CMC increased the viscosity of ileal digesta and the moisture of feces (P < 0.001). The crude mucin concentration and output at the ileum were higher (P < 0.05) in pigs fed CMC than those fed the control diet. Increasing intestinal content viscosity in pigs fed CMC had no significant effects on the ileal apparent digestibility of dry matter, organic matter, nitrogen, and minerals. The number of total ileal goblet cells per villus also was higher (+30%, P < 0.05) in pigs fed the CMC diet compared with controls. This increase was essentially accounted for by increased numbers of acidic and acidic sulfated mucin-containing cells (+30%, P < 0.05). Trends (P = 0.06) toward decreased numbers of neutral and acidic mucin-containing cells in ileal crypts were also noted. In conclusion, increasing intestinal content viscosity in weaned piglets fed CMC increased the ileal mucin output and numbers and maturation of goblet cells in ileal villi without effects on the apparent digestibility of the diet. KEY WORDS: * viscosity * intestine * piglet * goblet cells * mucin

Published
2005

12. Physiological response to the weaning in two pig lines divergently selected for residual feed intake.

Author

Montagne, Lucile, Gilbert, Hélène, Muller, Nelly, and Le Floc'h, Nathalie

Subjects
*SWINE, *MALNUTRITION, *SWINE breeding, *EFFECT of stress on animals, *ENVIRONMENTAL economics, *ANIMAL weaning
Abstract

Breeding efficient pigs is a way to reduce dietary costs and environmental waste. However, optimization of feed efficiency must not be linked to a decrease of the ability of animals to cope with stress, such as the weaning. This study characterizes the response after weaning of pigs from two lines divergently selected for residual feed intake (RFI) during growth. Animals of the low (L) RFI line are more efficient than animals from the high (H) RFI line. Thirty‐six piglets from each line weaned at 28 days of age were individually housed and fed a conventional dietary sequence. Their performance, behaviour, health and oxidative status, immune and nutritional parameters were followed during three weeks. Daily feed intake and growth rate of pigs from the LRFI line were 35% and 40% lower compared with HRFI (p < 0.001). Pigs from the LRFI‐line had lower total tract apparent digestibility (−6% for OM) and suffered more from undernutrition with a 167 and 55% higher plasmatic concentration of NEFA and urea compared with HRFI (p < 0.01). In the first week after the weaning, they had more diarrhoea and had a higher inflammatory status with concentration of haptoglobin 52% higher (p < 0.001). These piglets then seemed to adapt to the weaning conditions and to recover during the second and third weeks. Both lines had similar zootechnical performance and physiological characteristics at the end of the post‐weaning period. To conclude, the physiological responses to the weaning differed between lines. Pigs from the LRFI line, selected for greater feed efficiency, were more sensitive to the weaning stress. They were also more resilient as they finally adapted to the new condition and recovered to show similar performance results as pigs of the HRFI line. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

13. Traitement conservateur d'un second événement intra-mammaire homolatéral : intérêt de la classification d'irradiation partielle de GEC-ESTRO

Author

Montagne, Lucile, Université Nice Sophia Antipolis - Faculté de Médecine (UNS UFR Médecine), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), and Jean-Michel Hannoun-Lévi

Subjects
Irradiation partielle, Curiethérapie, Second traitement conservateur, Cancer du sein, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

AIM:Second ipsilateral breast tumor event (2ndIBTE) occurring after primary radio-surgical treatment can be treated by either salvage mastectomy or 2nd conservative treatment (2ndCT) including an accelerated partial breast re-irradiation (APBrI). We analyzed the impact of the GEC-ESTRO APBI classification (GAC) on the oncological outcome after APBrI.MATERIALS AND METHODS:Between 2000 and 2016, 159 patients (pts) underwent a 2ndCT. After lumpectomy, APBrI was performed using either low-dose (30-55 Gy reference isodose) or high-dose rate brachytherapy (28-34 Gy). Oncological outcome including 3rdIBTE, regional (RFS) or metastasis-free survival (MFS), specific (SS) and overall survival (OS) was analyzed according to GAC. Univariate (UVA) and multivariate analyses (MVA) were conducted to identify significant prognostic factors for 3rdIBTE.RESULTS:With a median follow-up of 71 months (range 62-85 months), 60 pts (42%), 61 pts (42.7%) and 22 pts (15.4%) were classified as low-risk (LR), intermediate-risk (IR) and high-risk (HR), respectively. For the whole cohort, 6-year 3rdIBTE-free survival, RFS, MFS, SS and OS rates were 97.4, 96.4, 90.3, 92.9 and 91.2%, respectively. Six-year 3rdIBTE-free survival rates for LR, IR and HR were 100, 95.8 and 92.9%, respectively (p = 0.003), while no significant differences were found between the three GAC groups for RFS, MFS, SS. In UVA, lympho-vascular invasion (p = 0.009), positive margins (p = 0.0001) and GAC high-risk group (p = 0.001) were considered as significant prognostic factors for 3rdIBTE, while, in MVA, high-risk group (p = 0.009) was the only prognostic factor.CONCLUSION:In case of 2ndIBTE, GAC could be used as a decision helping tool to discuss conservative or radical treatment options. Patient information remains crucial in order to accurately define the salvage therapy modalities.; Objectif :Un deuxième évènement intra-mammaire homolatéral (2e EIMH) dans les suites d’un traitement conservateur peut être pris en charge par mastectomie de rattrapage ou second traitement conservateur. Nous avons analysé l’impact de la classification d’irradiation partielle et accélérée du sein (IPAS) du GEC-ESTRO sur la survenue d’un 3e EIMH après 2e traitement conservateur.Matériel et Méthode :Entre 2000 et 2016, 159 patientes présentant un 2e EIMH ont été traitées par tumorectomie de rattrapage et ré-irradiation partielle accélérée par curiethérapie interstitielle de bas ou haut débit de dose. Notre objectif primaire était la survie sans 3e EIMH dans la cohorte totale et dans les trois groupes pronostiques de la classification IPAS du GEC-ESTRO. Nous avons également analysé la survie sans récidive régionale (SSR), sans métastase (SSM), spécifique (SS) et globale (SG). Des analyses uni-variée et multivariée ont été réalisées pour identifier un facteur pronostique pour un 3e EIMH.Résultats :Avec un suivi médian de 72 mois (62–85 mois), 60 patientes (42%), 61 patientes (42,7 %) et 22 patientes (15,4%) étaient classées respectivement à risque « faible », « intermédiaire » et « haut ». Pour la cohorte totale, le taux de survie sans 3e EIMH à 6 ans était de 97,4 % (CI 0,94- 1). La SSR, SSM, SS et SG à 6 ans étaient respectivement de 96,4%, 90,3%, 92,9% et 91,2%. Selon les groupes du GEC-ESTRO, les taux de survie sans 3ème EIMH à 6 ans étaient de 100% pour les risques faibles, de 95,8% pour les risques intermédiaires et de 92,9% pour le groupe haut risque (p=0.003). En analyse uni-variée, le groupe à haut risque (p = 0,0013), la présence d’emboles vasculaires (p = 0,009) et de marges positives (p=0.0001) étaient facteurs pronostics de 3e EIMH. En analyse multivariée, seul le groupe à haut risque (p = 0,008) restait facteur pronostic.Conclusion :En cas de 2e EIMH, la classification IPAS du GEC-ESTRO pourrait être utilisée comme un outil pronostique et aide à la décision thérapeutique dans le cadre d’un 2nd traitement conservateur.

Published
2019

17. APBI Versus Ultra-APBI in the Elderly With Low-Risk Breast Cancer: A Comparative Analysis of Oncological Outcome and Late Toxicity.

Author

Hannoun-Lévi, Jean-Michel, Montagne, Lucile, Sumodhee, Shakeel, Schiappa, Renaud, Boulahssass, Rabia, Gautier, Mathieu, Gal, Jocelyn, and Chand, Marie-Eve

Subjects
*BREAST cancer, *OLDER patients, *OVERALL survival, *OLDER people, *TREATMENT effectiveness, *HIGH dose rate brachytherapy, *ACCELERATED partial breast irradiation
Abstract

Purpose: Accelerated partial breast irradiation (APBI) represents a validated technique for low-risk breast cancer. Recently, ultra-APBI (uAPBI) using fewer than 5 fractions was described in the literature. We compared clinical outcomes and late toxicity after APBI or uAPBI in older patients.Methods and Materials: Two cohorts of older patients (aged ≥70 years) with low-risk breast cancer treated with APBI (interstitial brachytherapy) were analyzed retrospectively. A total dose of 34 Gy in10 fractions (APBI) or 16 Gy in 1 fraction (uAPBI) was delivered from 2004 to 2012 and from 2013 to 2018, respectively. Oncologic outcome analyzed the cumulative incidence of local relapse, regional relapse, and distant metastases with disease-free survival, cause-specific survival, and overall survival. Late toxicity and cosmetic results were investigated.Results: One hundred fifty-seven patients (APBI, n = 109 patients; uAPBI, n = 48 patients) underwent APBI according to the same selection criteria. Apart from the median follow-up (97 vs 72 months for APBI and uAPBI; P < .002), no significant difference was noted between the 2 groups. Regarding 6-year oncologic outcome, no significant difference was observed between APBI and uAPBI for local recurrence (1.3% vs 0%; P = .4), regional recurrence (2.5% vs 2.3%; P = .9), distant metastases (4.3% vs. 2.4%; P = .6), disease-free survival (85.2% vs. 82.2%; P = .8), cause-specific survival (96.7% vs. 96.2%; P = .9), and overall survival (86.7% vs. 82.2%; P = .7). Regarding late toxicity, no significant difference was observed between APBI and uAPBI (total complication number, 45 vs 33%; P = .173) with only grade 1 (88.4% vs. 95%) and grade 2 (11.6% vs. 5%) late toxicities (P = .677). Similarly, no significant difference was observed for excellent/good cosmetic results between the 2 cohorts (P = .98).Conclusions: We report the first study comparing APBI versus uAPBI in a cohort of older patients with low-risk breast cancer. No significant difference was found between the 2 treatment groups regarding oncologic outcome, late toxicity, and cosmetic result. uAPBI based on a single fraction of brachytherapy represents an attractive option for therapeutic de-escalation in older patients with breast cancer. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

18. Brachytherapy for oligometastatic prostate cancer to the penis.

Author

Martz, Nicolas, Benziane-Ouaritini, Nicolas, Gautier, Mathieu, Brenot-Rossi, Isabelle, Montagne, Lucile, Salem, Naji, Bodokh, Yohan, and Hannoun-Levi, Jean-Michel

Subjects
PENILE cancer, EXTERNAL beam radiotherapy, PROSTATE cancer, RADICAL prostatectomy, RADIOISOTOPE brachytherapy, PENILE induration
Abstract

The origin of penile metastases is in 70% of cases from primary pelvic cancers (genitourinary and recto-sigmoid primary tumors). The prognosis is poor and it is often associated with synchronous bone metastases at the time of diagnosis. We present the case of a 61-year-old patient who developed a penile induration 7 years after radical prostatectomy followed by adjuvant external beam radiation therapy for high-risk prostatic adenocarcinoma. Biopsies confirmed the metastatic localization and a detailed assessment failed to find any further remote lesions. Faced with this penile oligometastatic prostate cancer, we proposed an ablative treatment based on interstitial multi-catheter high-dose rate brachytherapy. At the six-month follow-up, clinical examination and 68Ga-PSMA-11-PET confirmed a complete response of the penile tumor without new lesion at a distance. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

20. Assessing the effect of dietary inulin supplementation on gastrointestinal fermentation, digestibility and growth in pigs: A meta-analysis

Author

Metzler-Zebeli, B.U., Trevisi, P., Prates, J.A.M., Tanghe, S., Bosi, P., Canibe, N., Montagne, Lucile, Freire, J., Zebeli, Q., University of Veterinary Medicine [Vienna] (Vetmeduni), Department of Agricultural and Food Science, University of Bologna, CIISA, Faculty of veterinary medicine, University of Lisbon, Nutrition sciences, Department of Animal Science, Aarhus University [Aarhus], Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), LEAF, Instituto Superior de Agronomia, Universidade de Lisboa (ULISBOA), Institute of animal nutrition and functional plant compounds, Department for farm animals and veterinary public health, and Vetmeduni Vienna

Subjects
Meta-analysis, Pig, Microbiota, Gastro-intestinal tract, [SDV.BA]Life Sciences [q-bio]/Animal biology, Fermentation, Inulin
Abstract

International audience; Inulin has been reported to improve the homeostasis in the gastrointestinal tract (GIT) of pigs by modulating the intestinal microbiota and fermentation. The present study aimed to quantify the relationship between dietary inulin and microbial response variables in digesta from the GIT and feces of weaned, growing and finishing pigs using a meta-analytical approach. We further examined the effect of dietary inulin on the coefficients of ileal (CLAD) and total tract apparent digestibility (CTTAD) of nutrients and ADG. Pig's starting body weight was considered the main inclusion criterion. Missing information about explanatory variables and few values available for response variables reduced the number of studies included. From the 33 included articles published between 2000 and 2016, individual sub-datasets for fermentation metabolites, bacterial abundances, CIAD, CTTAD and performance were built. Prediction models on the effect on inulin were computed accounting for inter- and intra-study variability. Dietary inulin levels ranged from 0.1 to 25.8%, whereby the median and mean inulin levels were 0.1-2% and 3-4%, respectively. Few of the investigated fermentation response variables were influenced by dietary inulin. Strong negative relationships were found between dietary inulin and gastric pH in weaned pigs (R-2 = 0.81; P < 0.001; n = 12), colonic enterobacteria (R-2 = 0.50; P < 0.001; n = 19) and fecal lactobacilli (R-2 = 0.41; P < 0.001; n = 26) throughout all production phases, whereas observed negative relationships between inulin and colonic bifidobacteria and fecal enterobacteria and Escherichia coli were of minor physiological relevance (P < 0.05). Moreover, increasing inulin levels negatively correlated with the CTTAD of crude protein (R-2 = 0.83; P < 0.001; n = 15), but they did not influence average daily gain of pigs. Best-fit models indicated that dietary crude protein amplified the effect of inulin on CTTAD of crude protein and gastric pH, but counteracted the inulin effect on fecal E. coli (P < 0.05). Accordingly, both pig's body weight and inulin decreased gastric pH and fecal lactobacilli but counteracted the inulin effect on colonic bifidobacteria and fecal E. coli (P < 0.05). In conclusion, this study supported a stimulatory effect of dietary inulin on gastric acid secretion, which may be favorable GIT health in weaned pigs. However, due to limiting information provided in the original studies, like dietary fructans or fibers, low numbers of observation and low inulin levels, relationships should be regarded as trends.

Published
2017
Full Text
View/download PDF

21. Development of e-learning resources by/for users: a win-win project for teachers ans students

Author

Faure, Justine, Jalam, G., Bonneau, Michel, Aguilera-Charles, C., Bodin, T., Drieu, C., Drouet, A., Guillou, M., Helary, L., Lebouter, M., Panaget, G., Montagne, Lucile, Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA), AGROCAMPUS OUEST, European Association for Animal Production (EAAP), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA)

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_COMPUTERSANDEDUCATION
Abstract

Post-graduate students are so-called digital native and usual users of numeric tools (web, social networks,software applications) on computers, smartphones, and touch tablets. They have free access anywhere andanytime to a variety of information. Their expectations as students have quickly changed with the numericinnovations in technologies. To match this new generation, learning approaches have to be playful, interactive,and based on visual resources rather than long texts. There is also a need to develop long-life skills. Thedevelopment of e-learning courses is an adaptive response of teachers to the changes in learning processes.An educational project was proposed to a group of 8 master students in animal science. The objective wasto make students actors of the computational development of e-learning resources to make them aware ofnumeric technologies in addition to knowledge and skills related to animal and livestock production. Theproject was based on the creation of an e-course linked to the FP7 EU-PLF program. It was expected that theinvolvement of motivated students in the design of the e-course might result in a creative tool correspondingto their needs. Based on basic knowledge in animal production, students proposed four different learningresources after a period of 60 h working in autonomy with minimal supervision of the teachers. Their resourcesconsisted of texts on livestock farming systems, sketches for dynamic schemes on physiological stages ofpig, self-assessment questionnaire, and theoretical growth curve. After validation of the resources by theteacher, the self-assessment questionnaire was tested with other students. The resources were also modifiedtoward a graphic design well adapted to on-line viewing. In a short time this student project management wasinstructive for them to select and write informative contents, using specific English vocabulary. Backgroundand skills in computational development and design were however a limitation and prevented direct on-linepublication. Development of such skills in animal science curriculum is a must.

Published
2016

22. EU-PLF e-course: a free on-line e-course to understand concepts of precision livestock farming

Author

Faure, Justine, Bonneau, Michel, Montagne, Lucile, Le Cozler, Yannick, Jalam, G., Verbrugge, A., BERCKMANS, D., Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA), AGROCAMPUS OUEST, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA), and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)

Subjects
[SDV]Life Sciences [q-bio]
Abstract

Precision Livestock Farming (PLF) technologies in farms offer a lot of new opportunities to improve animalwelfare, health and efficiency and reduce the environmental impact of animal production. Continuousmonitoring of animals throughout the use of cameras, microphones and sensors, generates data that needto be analysed to transform data into valuable information, helping farmers to take a better care of theiranimals. The EU-PLF e-course has been created to disseminate the main outputs of the FP7 Smart Farmingfor Europe project (EU-PLF) which aims to bring PLF tools from the lab to end-users in dairy, pig andpoultry farms in order to create value for the farmers and other stakeholders. The animal science team inAGROCAMPUS OUEST used results created by the EU-PLF project and contents of the advanced courseprovided by CIHEAM to design educational on-line resources. Three learning pathways were defined (animalscience students, suppliers of PLF technologies, professionals in animal production) to answer the specificneed of the various categories of stakeholders. The e-course contains basic knowledge, including examplesand methods required to analyse a study case. Seven units were generated for an equivalent of a two-day long training (16 h) but learners may spend more time depending on their needs. Dynamic schemes, self-assessment and videos of farmers, scientists and professionals make the course user-friendly. The course will be available at the following address: http://plf.agrocampus-ouest.fr. Its free accessibility will allow a wide appropriation by individual learners but it can also be used as a teaching tool for educational and professional trainers. Quick changes and innovations in PLF technologies will require a regular update of the e-course content via continuous interaction with end-users, scientists, teachers, informatics engineers and PLF providers.

Published
2016

23. Dynamic response to weaning of two lines of pigs divergently selected on residual feed intake

Author

Muller, Nelly, Gilbert, Hélène, Robert, F., ROGER, L., Montagne, Lucile, Unité Expérimentale Porcs Rennes (UE PR), Institut National de la Recherche Agronomique (INRA), Génétique Physiologie et Systèmes d'Elevage (GenPhySE ), École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Conseils et Compétences en Productions Animales (CCPA), Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), European Project: 613574,EC:FP7:KBBE,FP7-KBBE-2013-7-single-stage,PROHEALTH(2013), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-École nationale supérieure agronomique de Toulouse (ENSAT), Université de Toulouse (UT)-Université de Toulouse (UT), Groupe CCPA, ProdInra, Migration, and Sustainable intensive pig and poultry production - PROHEALTH - - EC:FP7:KBBE2013-12-01 - 2018-11-30 - 613574 - VALID

Subjects
[SDV] Life Sciences [q-bio], [SDV.GEN]Life Sciences [q-bio]/Genetics, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, [SDV]Life Sciences [q-bio], [INFO]Computer Science [cs], [SDV.GEN] Life Sciences [q-bio]/Genetics, [SDV.GEN.GA] Life Sciences [q-bio]/Genetics/Animal genetics, [INFO] Computer Science [cs]
Abstract

International audience; Breeding efficient pigs is a way to reduce dietary costs and environmental waste. However, optimisation of feed efficiency must not be linked to a decrease in the ability of animals to cope with challenges or stress, such as during the weaning period. This study aimed to characterize the response of two lines of pigs divergently selected for residual feed intake (RFI), an indicator of feed efficiency, calculated as the difference between observed and theoretical feed intake estimated from maintenance and production requirements. Animals of the RFI- line (- for under-consumption) are more efficient than animals from the RFI+ line (+ for overconsumption). Thirty six piglets from each line were weaned at 28 days of age and housed in individual pens. Their zootechnical performance and physiological characteristics were followed during three weeks. Piglets from the more efficient line (RFI-) appeared more affected by weaning during the first week than piglets from the RFI+ line. Daily feed intake and growth rate of pigs from the RFI- line were 65% and 25% lower (P

Published
2016

24. Responses to weaning in two pig lines divergently selected on residual feed intake depending on diet

Author

Gilbert, Hélène, Ruesche, Julien, Muller, Nathalie, Billon, Yvon, Robert, F., ROGER, L., Montagne, Lucile, Génétique Physiologie et Systèmes d'Elevage (GenPhySE ), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-École nationale supérieure agronomique de Toulouse [ENSAT], Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA), UE 1372 Génétique, Expérimentation et Système Innovants, Institut National de la Recherche Agronomique (INRA)-Génétique animale (G.A.)-Physiologie Animale et Systèmes d'Elevage (PHASE), Institut National de la Recherche Agronomique (INRA)-Génétique, Expérimentation et Système Innovants (GenESI), CCPA,Centrale Coopérative de Productions Animales (CCPA), European Project: 613574, Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-École nationale supérieure agronomique de Toulouse (ENSAT), Université de Toulouse (UT)-Université de Toulouse (UT), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Génétique, Expérimentation et Système Innovants (GenESI), Institut National de la Recherche Agronomique (INRA), Groupe CCPA, École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)

Subjects
pig, stress, weaning, [SDV]Life Sciences [q-bio], feed efficiency, genetics
Abstract

Responses to weaning in two pig lines divergently selected on residual feed intake depending on diet. 67. Annual Meeting of the European Federation of Animal Science (EAAP)

Published
2016

26. Mitomycin and 5‐fluorouracil for second‐line treatment of metastatic squamous cell carcinomas of the anal canal.

Author

Saint, Angélique, Evesque, Ludovic, Falk, Alexander T., Cavaglione, Gérard, Montagne, Lucile, Benezery, Karen, and Francois, Eric

Subjects
ANUS, SQUAMOUS cell carcinoma, ELECTRONIC publications, PROGRESSION-free survival
Abstract

Background: Metastatic squamous cell carcinomas (SCC) of the anal canal are rare and there is no international consensus on their second‐line management. 5‐Fluorouracil (5‐FU) and mitomycin in combination with radiotherapy is the standard for locally advanced forms but its efficacy in metastatic stage has never been evaluated. Patients and methods: We report a retrospective analysis of patients treated with 5‐FU and mitomycin from 2000 to 2017 in our institution for a metastatic SCC of the anal canal after failure of platinum‐based regimen. The main outcome was progression‐free survival (PFS) and the secondary outcomes were overall survival (OS), response rate, and toxicity. Results: Nineteen patients, 15 women and four men, with a median age of 57 years were identified (range, 40‐79 years). Patients received a median of three cycles (1‐7) of mitomycin 5‐FU. A dose reduction was necessary in six patients (31.6%), one patient had to discontinue treatment following toxicity and no death was due to treatment toxicity was reported. An objective response was observed in five patients (26.4%, 95% CI 6.6‐46.2) including one complete response, six patients (31.6%, 95% CI 10.7‐52.5) showed tumor stabilization. Median PFS and OS were 3 months [95% CI 1‐5] and 7 months [95% CI 2.2‐11.8]. Responder had a median duration of response of 4 months [95% CI 1.8‐6.1] and one patient had 23 months duration of response. No significant difference was noted for PFS and OS for patients previously treated with mitomycin and 5‐FU at a local stage. Conclusion: Mitomycin and 5‐FU regimen provides tumor control with acceptable tolerance. It is an option for patients with metastatic SCC of the anal canal after failure of platinum‐based chemotherapy. [Correction added on 9 October 2019, after first online publication: '5‐FU' was inadvertently removed from the Results and Conclusion and has now been added to the text.] [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

27. Feeding behaviour and pre-prandial status affect post-prandial plasma energy metabolites and insulin kinetics in growing pigs fed diets differing in fibre concentration.

Author

Quemeneur, Katia, Labussiere, Etienne, Le Gall, Maud, Lechevestrier, Yannick, and Montagne, Lucile

Subjects
ANIMAL experimentation, DIETARY supplements, DYNAMICS, ENERGY metabolism, FASTING, DIETARY fiber, FOOD habits, HYPOGLYCEMIA, INGESTION, INSULIN, PLANT proteins, PLEASURE, SWINE, FOOD portions
Abstract

Variations in feeding behaviour between animals result from individual variations in their metabolism as affected by diet composition. The study aimed to link the within-day dynamics of voluntary feed intake and those of blood metabolites and insulin in growing pigs having ad libitum access to feed and receiving diets differing in dietary fibre levels and aleurone supplementation. A total of forty pigs (body weight: 35 kg) had access to diets provided ad libitum , which differed by fibre content (13 or 18 % neutral-detergent fibre) and aleurone supplementation (0, 2 or 4 g/kg). Feeding behaviour was individually recorded for 1 week. The kinetic of plasma metabolites and insulin was followed for 1 h after a voluntary test meal. Dietary fibre level did not affect the daily feed intake but increased meal size and meal duration. Aleurone supplementation (4 g/kg) decreased the daily feed intake and number of meals. Dietary fibre level only decreased insulin concentration measured 15 min after meal beginning. Aleurone supplementation (4 g/kg) decreased glycaemia in the first hour after the meal and insulinaemia 15 min after the meal. Free access to feed led to high variability in pre-prandial metabolites and insulin concentrations, resulting in different test meal size irrespective of diet composition. Animals were then spread over different profiles combining feeding behaviour and fasted status to explain different profiles of regulation of feed intake. Plasma metabolites and insulin kinetics were affected by diet composition but also by animal characteristics. Individual variability should be considered when diet composition is used to modulate feeding behaviour. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

28. Difference in short-term responses to a high-fiber diet in pigs divergently selected for residual feed intake

Author

Montagne, Lucile, Loisel, Florence, Le Naou, Thierry, Gondret, Florence, Gilbert, Hélène, Le Gall-Le Bleiz, Maud, Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Université européenne de Bretagne - European University of Brittany (UEB), Génétique Animale et Biologie Intégrative (GABI), AgroParisTech-Institut National de la Recherche Agronomique (INRA), Laboratoire de Génétique Cellulaire (LGC), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), ANR PIGFEED, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées

Subjects
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences, Swine, [SDV.BA]Life Sciences [q-bio]/Animal biology, Organ Size, digestion, dietary fiber, Animal Feed, Diet, Intestines, Eating, growing pig, residual feed intake, Animals, Animal Nutritional Physiological Phenomena, Selection, Genetic, metabolism, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.BDD]Life Sciences [q-bio]/Development Biology
Abstract

Residual feed intake (RFI), defined as the difference between observed and predicted feed intakes, has been explored as a relevant selection criterion to improve feed efficiency in growing pigs. Previous studies exploring the genetic and physiological bases of RFI have been focused on pigs fed a regular diet. The aim of this study was to evaluate the effects of RFI selection on pigs' ability to digest and metabolize a diet enriched in fiber. After 11 wk of age, pigs of 2 lines divergently selected for RFI (low or high; n = 7 pairs of littermates in each line) were fed either a control diet (133 g NDF and 9.69 MJ NE/kg) or a high-fiber diet (244 g NDF and 8.36 MJ NE/kg) for 3 wk. Irrespective of diet, ADFI and water consumption were lower (P < 0.001) in the low RFI line, whereas G:F over the test period was 16% greater (P < 0.001) in that line compared with the high RFI line. There was no line-associated difference in the digestibility of nutrients and energy, despite a lighter digestive tract (-6.4%, P = 0.04) and a lower colon weight (-8.6%, P = 0.03) in the low RFI pigs than in the high RFI pigs. As compared with the control diet, ADFI was reduced (-7.5%, P < 0.001) in both lines when fed a high-fiber diet, but ADG and G:F were lowered for the high RFI line only (P < 0.05). The high-fiber diet decreased (P < 0.01) the digestibility values of nutrients and energy similarly in both lines. However, it increased the ratio of acetate to propionate concentrations in the distal part of the gastrointestinal tract for the high RFI line only (P < 0.07). The pattern of response of plasma metabolites and hormones to a meal test was altered by RFI selection, but it was not affected by the diet. The increase in glucose concentration after meal ingestion was more pronounced (P < 0.05) in the low RFI line, and long-lasting plasma concentrations of lactate tended to be lower (P < 0.10) in the low RFI line than in high RFI line. Plasma NEFA concentrations were greater in that line compared with the high RFI line. The activity levels of catabolic enzymes in muscle and the liver did not differ between lines and diets. In conclusion, the low RFI pigs seem to better utilize a high-fiber diet than high RFI pigs. This was not associated with marked changes in digestion, and the underlying metabolic mechanisms remain to be clarified.

Published
2014
Full Text
View/download PDF

29. Responses to weaning in two pig lines divergently selected for residual feed intake depending on diet 1.

Author

Gilbert, Hélène, Ruesche, Julien, Muller, Nelly, Billon, Yvon, Begos, Vincent, and Montagne, Lucile

Subjects
HAPTOGLOBINS, ANIMAL nutrition, ANIMAL feeds, BLOOD sampling, FATTY acids, PIGLETS
Abstract

Weaning is a stress every piglet has to face. It is a main cause of antibiotic uses due to digestive disorders. In this study, response to weaning was analyzed in pigs from two lines divergently selected for residual feed intake (RFI) during growth. A total of 132 pigs from each line, housed per line and diet in conventional postweaning units of 12 castrated males and 12 females, were fed either a conventional control (two successive diets) or a complex (three successive diets) dietary sequence during the postweaning period (4 to 10 wk of age). BWs were recorded at weaning (days 0 and 28 of age), days 1, 2, 6, 12, 19, 26, and 42 (10 wk of age), and at 23 wk of age. Feces texture was examined before weaning (day −1), at day 1, 2, 6, 12, and 19. Feed intake was recorded at pen level from days 0 to 42 after weaning, and individually thereafter. Plasma was collected after blood samplings at days −1, 6, 19, and 42 on half of the piglets: all piglets of a given sex in each pen were sampled, to achieve a balanced number across factors. Pigs of the low RFI (LRFI) line were heavier at weaning, had greater glucose concentration, and lower levels of diarrhea at days 1 and 2 than pigs from the high RFI (HRFI) line (P < 0.01). At day 42, there was no BW difference between lines, and G:F ratio did not differ between lines (P = 0.40). The LRFI pigs had lower feed intake and growth rate from day 0 to day 19 (P < 0.005), and greater plasma concentration of non-esterified fatty acid (P < 0.001), indicating an increased mobilization of body lipids and proteins immediately after weaning compared with HRFI pigs. They also had greater levels of diarrhea at day 6 (22% for LRFI vs. 14% for HRFI, P = 0.002), but the concentration of plasma haptoglobin did not indicate acute inflammation. The complex diet sequence improved feed intake and growth, and reduced diarrhea, mainly in the LRFI line (P < 0.001). To conclude, pigs from the LRFI line were more negatively affected by weaning stress, but managed to recover afterwards. The complex diet sequence ameliorated some of the negative effects that weaning had on the LRFI pigs, but limited effects of nursery period feeding sequence on growth performance were observed during the growing-finishing period. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

30. Response to a high level fibers diet in pigs divergently selected for residual feed intake

Author

Hauptli, L., Priet, Aurélia, Gilbert, Hélène, Montagne, Lucile, Universidade Federal do Paraná (UFPR), UE 1372 Génétique, Expérimentation et Système Innovants, Institut National de la Recherche Agronomique (INRA)-Génétique animale (G.A.)-Physiologie Animale et Systèmes d'Elevage (PHASE), Institut National de la Recherche Agronomique (INRA)-Génétique, Expérimentation et Système Innovants (GenESI), Laboratoire de Génétique Cellulaire (LGC), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA), ProdInra, Archive Ouverte, Génétique, Expérimentation et Système Innovants (GenESI), Institut National de la Recherche Agronomique (INRA), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio]
Abstract

Session 53. Feed efficiency in non-ruminants; absent

Published
2013

31. Impact of feed restriction on health, digestion and performance of growing pigs housed in poor hygiene conditions

Author

Le Floc'h-Burban, Nathalie, Knudsen, Christelle, Montagne, Lucile, Merlot, Elodie, Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA), Tissus animaux, nutrition, digestion, écosystème et métabolisme (TANDEM), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-École nationale supérieure agronomique de Toulouse [ENSAT], AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-INP. Ecole Nationale Supérieure Agronomique de Toulouse, and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées

Subjects
[SDV]Life Sciences [q-bio]
Abstract

Health deterioration in pigs results in significant economic losses caused by growth check and morbidity. Feed restriction is commonly applied to preserve gut health and to limit antibiotic use. This study assessed the effect of a feed restriction on growing pigs submitted to a low grade inflammation induced by the degradation of the environmental hygiene. The experiment was run in two replicates of 40 pigs each. Twenty blocks of 4 pigs, half castrated males and half females, were selected, 3 weeks after weaning, at 7 weeks of age. Within a block, the 4 littermates had a similar body weight and each pig was affected to an experimental group according to a 2 x 2 factorial design: 2 feeding levels, ad libitum (AL) and restricted (R) at 60% of AL, and 2 levels of environmental hygiene. Pigs were housed individually throughout the experiment. Feed restriction was applied from 61 to 89 d of age. From 61 to 68 d of age, piglets were housed in a post weaning unit. At 68 d of age, pigs were transferred in a growing unit where 2 pigs per block were housed in an unclean environment (no cleaning and disinfection of the rooms after a previous occupation by non-experimental pigs) and the others in a clean environment for 5 weeks (102 d of age). Pigs were fed a standard growing diet containing 0.4% of TiO2 as an indigestible marker of digestibility. Growth performance was weekly recorded and blood (at 61, 75 and 89 d of age) and fecal (at 88 and 98 d of age) samples were collected to measure indicators of inflammation (plasma haptoglobin, blood total leucocytes, granulocytes and lymphocytes) and nutrient digestibility. Feces consistency was monitored daily to detect diarrheas. R pigs were lighter than AL pigs at 68 d of age (24.1 kg vs 26.4 kg). Feed restriction decreased daily weight gain, increased the feed conversion ratio and improved crude protein digestibility. Poor hygiene conditions decreased growth performance and fecal digestibility of all nutrients. Haptoglobin concentrations and leucocyte and granulocyte numbers were higher in poor hygiene conditions, confirming that the model was effective to induce an inflammatory response. Nevertheless, feed restriction did not modify the inflammatory response but reduced the occurrence of diarrhea in poor hygiene conditions. Apart from digestive disorders, this study showed no beneficial effect of feed restriction on the inflammatory response caused by poor hygiene conditions.

Published
2013

32. Effects of host genetics and environmental conditions on fecal microbiota composition of pigs.

Author

Kubasova, Tereza, Davidova-Gerzova, Lenka, Babak, Vladimir, Cejkova, Darina, Montagne, Lucile, Le-Floc'h, Nathalie, and Rychlik, Ivan

Subjects
SWINE nutrition, BODY weight, RIBOSOMAL RNA, LACTOBACILLUS, BACTEROIDES
Abstract

Since microbiota may influence the physiology of its host including body weight increase, growth rate or feed intake, in this study we determined the microbiota composition in high or low residual feed intake (HRFI and LRFI) pig lines, of different age and/or subjected to sanitary stress by sequencing the V3/V4 variable region of 16S rRNA genes. Allisonella, Megasphaera, Mitsuokella, Acidaminococcus (all belonging to Firmicutes/class Negativicutes), Lactobacillus, Faecalibacterium, Catenibacterium, Butyrivibrio, Erysipelotrichaceae, Holdemania, Olsenella and Collinsella were more abundant in HRFI pigs. On the other hand, 26 genera including Bacteroides, Clostridium sensu stricto, Oscillibacter, Paludibacter, Elusimicrobium, Bilophila, Pyramidobacter and TM7 genera, and Clostridium XI and Clostridium XIVa clusters were more abundant in LRFI than HRFI pigs. Adaptation of microbiota to new diet after weaning was slower in LRFI than in HRFI pigs. Sanitary stress was of relatively minor influence on pig microbiota composition in both tested lines although abundance of Helicobacter increased in LRFI pigs subjected to stress. Selection for residual feed intake thus resulted in a selection of fecal microbiota of different composition. However, we cannot conclude whether residual feed intake was directly affected by different microbiota composition or whether the residual feed intake and microbiota composition are two independent consequences of yet unknown genetic traits differentially selected in the pigs of the two lines. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

33. Digestive utilization of diets with low or high level of fibers in pigs divergently selected for residual feed intake

Author

Montagne, Lucile, Le Gall-Le Bleiz, Maud, Gilbert, Hélène, Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Génétique Animale et Biologie Intégrative (GABI), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Laboratoire de Génétique Cellulaire (LGC), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA), Ecole Nationale Vétérinaire de Toulouse (ENVT), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)

Subjects
[SDV]Life Sciences [q-bio]
Abstract

Session II : Nutrient digestion and absorbtion; Residual feed intake (RFI) is the difference between observed and theoretical daily feed intake (DFI) estimated from maintenance and production requirements. Genetic selection to lower RFI is considered to improve feed efficiency. Divergent selection on RFI was conducted for 6 generations in 2 Large White lines: the RFI+ consumed more feed than predicted compared with the RFI–. Metabolism and activity could contribute to RFI differences between the lines. Digestion has been previously reported not to differ between these lines when pigs were fed a regular diet. This study aimed to determine the digestibility coefficients of a high fiber (244 g NDF - 8.36 MJ NE/kg) and a control diets (133 g NDF - 9.69 MJ NE/kg), to evaluate the impact of the selection on the lines’ ability to cope with a digestive challenge. Seven pairs of littermates were used in each line. Pigs were individually housed from 10 to 15 wk of age. At 12 wk, one pig from each pair received either the control or the high fiber diet for 3 wk. Titanium dioxide was included in the diet as an indigestible marker to determine the apparent digestibility. With the control diet, ADFI was greater in RFI+ than in RFI– pigs (1654 vs. 1336 g/d, P < 0.001) for a similar final BW (44.75 kg for the 2 lines). With the high fiber diet, DFI was 9% lower compared with the control (P < 0.01) and growth rate was reduced (728 vs. 866 g/d; P < 0.001) for RFI+ pigs. The diet did not significantly affect the performances of RFI– pigs. There was no line effect on digestibility coefficients, irrespective of the digestive site and of the diet. Increasing the dietary fiber level led to decreased digestibility coefficients of nutrients and energy similarly for the 2 lines (58.4 vs. 70.2% for ileal and 70.6 vs. 80.9% for fecal N digestibility for highfiber vs. control diet; P < 0.001). To conclude, apparent digestibility coefficient did not contribute to explain the difference of RFI between the 2 lines, despite different line responses on DFI and growth rate when fed the high fiber diet. RFI– line seems to better valorize high fiber diet than RFI+.

Published
2012

34. Feed restriction applied after weaning has different effects on pig performance and health depending on the sanitary conditions

Author

Pastorelli, H., Le Floc'H, N., Merlot, E., Meunier-Salaun, MC., Van Milgen, J., Montagne, Lucile, Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)

Subjects
Male, pig, growth, weaning, AGRICULTURE, DAIRY & ANIMAL SCIENCE, Sus scrofa, Housing, Animal, feed restriction, Diet, sanitary conditions, [SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies, Animals, Female, Animal Husbandry, Caloric Restriction
Abstract

Feed restriction may be a strategy used by farmers to limit digestive disorders after weaning. The objective of this study was to evaluate the effect of feed restriction applied 1 wk after weaning on growth performance and health of pigs reared in 2 different sanitary conditions (Good vs. Poor; managed in opposite ways with respect to cleaning, animal density, and preventive antibiotic use) and confronted with stressful common farming practices (i.e., diet transition and building transfer). At weaning at 4 wk of age, 48 pigs were assigned to 1 of the 4 experimental treatments consisting of 2 sanitary conditions and 2 feeding levels (ad libitum vs. restricted). At 2 d after weaning, restricted pigs received 20% of the feed quantity consumed by ad libitum pigs. The feeding level of the restricted pigs was gradually increased to attain ad libitum feeding on d 8. Imposed stressful conditions occurred at d 12 (the weaner diet replaced the starter diet), d 33 (transfer of pigs from the weaner unit to the grower unit), and d 47 (the grower diet replaced the weaner diet). This allowed 4 distinguishing phases: I, from 0 to 11 d; II, from 12 to 32 d; III, from 33 to 46 d; and IV, from 47 to 60 d after weaning. Poor sanitary conditions resulted in decreased growth performance during phase I (P < 0.001) and III (P < 0.01), and the final BW of pigs kept in Poor sanitary conditions was 4 kg less (P = 0.02) than those kept in Good sanitary conditions. Plasma haptoglobin concentration was increased on d 12 after weaning (P = 0.001) as was the occurrence of soft feces during phases II and III (P ≤ 0.05) in Poor sanitary conditions. In both sanitary conditions, the restricted feeding level resulted in decreased ADG (P < 0.001), increased plasma haptoglobin and salivary cortisol concentrations, and feeding-associated behaviors (P < 0.05) during phase I. In Poor sanitary conditions, feed restriction was very detrimental and differences in ADFI and ADG between restricted and ad libitum pigs increased with time (P = 0.05). Conversely, in Good sanitary conditions, restricted pigs attained the BW of ad libitum pigs before the end of the experiment. In conclusion, imposing feed restriction on pigs during the first days after weaning does not seem to be an effective strategy to decrease the negative effects of Poor sanitary conditions; rather, it reinforces these effects.

Published
2012
Full Text
View/download PDF

35. Comparative effects of level of dietary fiber and sanitary conditions on the growth and health of weanling pigs

Author

Montagne, Lucile, Le Floc'H, N., Arturo-Schaan, M., Foret, R., Urdaci, MC., Le Gall, M., Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Conseils et Compétences en Productions Animales (CCPA), and École Nationale d'Ingénieurs des Travaux Agricoles - Bordeaux (ENITAB)

Subjects
Time Factors, Denaturing Gradient Gel Electrophoresis, Animal/*standards, AGRICULTURE, DAIRY & ANIMAL SCIENCE, Fatty Acids, Volatile/metabolism, Animal Feed/*analysis, Animal Husbandry/*standards, Dietary Fiber/*pharmacology, [SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies, Housing, Animals, Diet/*veterinary, Animal Nutritional Physiological Phenomena, Swine/*growth & development
Abstract

International audience; There are conflicting results on the growth and health of weanling pigs (Sus scrofa) fed high-fiber diets, and responses may differ according to sanitary conditions. This study was conducted to explore the growth, health, and fecal microbiota of weanling pigs fed either low- or high-fiber diets in 2 different sanitary conditions. Forty-eight pigs weaned at 28 d of age were individually housed in "good" (clean) or "poor" (unclean) sanitary conditions. During 2 consecutive phases, pigs were fed 2 diets containing a low (control) or high level of fiber: 121 or 169 g/kg total dietary fiber (TDF) for Phase I and 146 or 217 g/kg for Phase II, which lasted 15 and 20 d, respectively. This led to 4 experimental treatments in Phase I in a 2 × 2 factorial arrangement (2 sanitary conditions × 2 diets) and 8 experimental treatments in Phase II in a 2 × 2 × 2 factorial arrangement (2 sanitary conditions × 2 diets in Phase I × 2 diets in Phase II). The poor sanitary conditions led to a reduced G:F (0.617 vs. 0.680 for poor and good sanitary conditions, respectively; P = 0.01) over the entire experimental period. The number of pigs with diarrhea in Phase I tended to be greater in the poor sanitary conditions with the high-fiber diet than the control diet (7 vs. 3 pigs, P = 0.07). Enteroccocus was prominent in feces of these diarrheic pigs. At 5 wk after weaning, compared with good sanitary conditions, the fecal microbiota of pigs housed in poor sanitary conditions was characterized by more Lactobacillus (9.24 vs. 8.34 log cfu/g, P < 0.001), more Enterobacteria (6.69 vs. 5.58 log cfu/g, P < 0.001), and less anaerobic sulfite bacteria (3.72 vs. 5.87 log cfu/g; P < 0.001). The feces of pigs in poor sanitary conditions contained more total VFA and proportionally more butyrate (9.7 vs. 5.7% for poor and good conditions, respectively, independently of dietary treatment, P < 0.001). At 5 wk after weaning, feces of pigs fed the high-fiber diet during Phase II contained less Enterococcus bacteria than pigs fed the control diet (4.06 vs. 4.56 log cfu/g; P = 0.05), and more total VFA with a decreased proportion of branched-chain fatty acids (5.0 vs. 6.1%; P = 0.006). To conclude, feeding pigs a high-fiber diet in the immediate period after weaning is probably an additional risk factor for slower BW gain, especially in poor sanitary conditions.

Published
2012
Full Text
View/download PDF

36. Description par une approche méta-analytique des réponses d'ingestion et de croissance de porcelets sevrés soumis à une infection bactérienne digestive

Author

Pastorelli, Hélène, Jaap van Milgen, Lovatto, Paulo Alberto, Montagne, Lucile, Universidade Federal de Santa Maria (UFSM), Systèmes d'élevage, nutrition animale et humaine (SENAH), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Universidade Federal de Santa Maria = Federal University of Santa Maria [Santa Maria, RS, Brazil] (UFSM), AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA), and Campus Camobi

Subjects
base de données, modèle de prédiction, alimentation animale, santé animale, [SDV]Life Sciences [q-bio], infection bactérienne, META-ANALYSE, [SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies, ingestion, croissance animale, [INFO]Computer Science [cs], nutrition animale, porcelet, porc
Abstract

Description par une approche méta-analytique des réponses d'ingestion et de croissance de porcelets sevrés soumis à une infection bactérienne digestive La perturbation de la santé diminue l'ingestion volontaire et la croissance des animaux. Les objectifs de ce travail sont de décrire en fonction du temps, par méta-analyse, la baisse d'ingestion et de croissance observée chez des porcelets sevrés soumis à des infections bactériennes digestives. La base de données utilisée regroupe les valeurs de consommation moyenne journalière et de gain moyen quotidien de porcelets expérimentalement infectés, issues de 29 essais publiés. Les réponses en fonction de la durée de la période de mesure, sont modélisées à l'aide des fonctions linéaires ou curvilinéaires plateau. L'analyse de la corrélation entre croissance et ingestion permet de quantifier la baisse de croissance non liée à la baisse d'ingestion. L'amplitude maximale de la réponse est plus importante pour la croissance que pour l'ingestion (85% vs 15% de différence entre animaux infectés et témoins en % des témoins). L'ingestion des animaux perturbés recouvre celle des témoins plus de 40 jours après le début de l'infection. Le plateau est atteint plus rapidement pour la croissance (15 jours), mais la vitesse de croissance des animaux ayant subis l'infection reste inférieure de 8%. La réduction de la croissance non expliquée par la baisse d'ingestion, dépend du temps de la mesure. Pour conclure, ce travail peut être un préalable à la prise en compte de phases de perturbation de la santé, dans des modèles de prédiction de la croissance des porcs.

Published
2011

37. Sustainable pig production in the EU. An example of Erasmus intensive teaching programme

Author

Montagne, Lucile, Bosi, P., Boudry, C., Cain, P.J., Couvreur, S., Franks, J.R., Guy, J., Lundeheim, N., Systèmes d'élevage, nutrition animale et humaine (SENAH), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, EAAP, AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA), and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)

Subjects
[SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies
Abstract

Sustainable pig production in the EU. An example of Erasmus intensive teaching programme

Published
2010

38. Quantification of the reduction in voluntary feed intake and growth after a digestive challenge in post-weaned piglets

Author

Pastorelli, H., Van Milgen, J., Lovatto, P.A., Montagne, Lucile, Systèmes d'élevage, nutrition animale et humaine (SENAH), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Campus Camobi, Universidade Federal de Santa Maria (UFSM), AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA), and Universidade Federal de Santa Maria = Federal University of Santa Maria [Santa Maria, RS, Brazil] (UFSM)

Subjects
CROISSANCE ANIMALE, fluids and secretions, integumentary system, [SDV]Life Sciences [q-bio], animal diseases, POST-SEVRAGE, [SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies, [INFO]Computer Science [cs], bacterial infections and mycoses, ComputingMilieux_MISCELLANEOUS, NOURRITURE
Abstract

Quantification of the reduction in voluntary feed intake and growth after a digestive challenge in post-weaned piglets

Published
2010

39. Quantification of the reduction of voluntary feed intake in pigs observed in pigs with different sanitary challenges

Author

Montagne, Lucile, Lovatto, P.A., Van Milgen, J., Systèmes d'élevage, nutrition animale et humaine (SENAH), AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)

Subjects
[SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies
Abstract

Quantification of the reduction of voluntary feed intake in pigs observed in pigs with different sanitary challenges

Published
2009

40. Sites of nutrient digestion in growing pigs: Effect of dietary fiber

Author

Wilfart, Aurélie, Montagne, Lucile, Simmins, Philip Howard, Van Milgen, Jaap, NOBLET, Jean, Systèmes d'Elevage, Nutrition Animale et Humaine (SENAH), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Rennes, Danisco Animal Nutrition, and Ecole Nationale Supérieure Agronomique de Rennes-Institut National de la Recherche Agronomique (INRA)

Subjects
DIETARY FIBER, DIGESTION, [SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies, ENDOGENOUS SECRETION, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2007
Full Text
View/download PDF

41. Dietary fibre and indigestible protein increase ileal glycoprotein output without impacting colonic crypt goblet cells in weaned piglets

Author

Piel, Christelle, Montagne, Lucile, Sève, Bernard, Lalles, Jean Paul, Systèmes d'Elevage, Nutrition Animale et Humaine (SENAH), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Rennes, and ProdInra, Migration

Subjects
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences, [SDV.SA] Life Sciences [q-bio]/Agricultural sciences, CRYPTE INTESTINALE, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2006

42. Double cannulated pig: an animal model to study digesta transit along the gut

Author

Wilfart, Aurélie, Montagne, Lucile, Simmins, H., Noblet, Jean, van Milgen, Jaap, Systèmes d'Elevage, Nutrition Animale et Humaine (SENAH), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Rennes, Danisco, and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], [INFO]Computer Science [cs], [INFO] Computer Science [cs], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2006

43. Influence of dietary phasolein level on feed intake, growth, gut characteristics and protein digestibility in rats

Author

Montoya, Carlos Alexander, Lalles, Jean Paul, Montagne, Lucile, Beebe, S., Souffrant, W.B., Leterme, P., ProdInra, Migration, Unité mixte de recherche veau et porc (UMR VP), and Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Rennes

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], RAT, [INFO]Computer Science [cs], [INFO] Computer Science [cs], ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2004

44. Quantification of mucin in ileal digesta of piglets using a new enzyme-linked immunosorbent assay

Author

Piel, Christelle, Montagne, Lucile, Salgado, Paulo, Lalles, Jean Paul, Unité mixte de recherche veau et porc (UMR VP), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Rennes, and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], [INFO]Computer Science [cs], [INFO] Computer Science [cs], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2003

45. Cereal and protein sources influence the proliferation of enterotoxigenic Escherichia coli in the gastrointestinal tract of piglets after weaning

Author

Montagne, Lucile, Lockwood, F.S., Lalles, Jean Paul, Hampson, D.J., Pluske, J.R., Unité mixte de recherche veau et porc (UMR VP), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Rennes, and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], [INFO]Computer Science [cs], [INFO] Computer Science [cs], ComputingMilieux_MISCELLANEOUS, RIZ
Abstract

International audience

Published
2003

46. Addition of carboxymethylcellulose to diets based on animal proteins and malto-dextrins does not induce gut disorders and colibacillosis post-weaning in piglets

Author

Lalles, Jean Paul, Boudry, Gaëlle, Favier, C., Montagne, Lucile, Piel, C., SÈVE, B., Systèmes d'élevage, nutrition animale et humaine (SENAH), AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA), and Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST

Subjects
[SDV]Life Sciences [q-bio]
Abstract

absent

Published
2003

47. A review of interactions between dietary fibre and the intestinal mucosa, and their consequences on digestive health in young non-ruminant animals

Author

Montagne, Lucile, Pluske, J.R., Hampson, D.J., Unité mixte de recherche veau et porc (UMR VP), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Rennes, and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], [INFO]Computer Science [cs], [INFO] Computer Science [cs], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2003

48. Quantification of mucin in ileal digesta of piglets using a new anzyme-linked immunosorbent assay

Author

Piel, Christelle, Montagne, Lucile, Salgado, Paulo, and Lallès, Jean-Paul

Subjects
Expérimentation, Porcelet, Digestibilité, Régime alimentaire, L50 - Physiologie et biochimie animales, L73 - Maladies des animaux
Abstract

A specific ELISA for pig gastrointestinal mucin was set up after mucin purification and specific antibody preparation. The aim was to quantify mucin contribution to ileal endogenous losses. This assay was sensitive, reproducible, and recognized well mucin in stomach and intestinal scrapings of pigs but not trout. Cross-reactivity was noted with digesta of chicken, rabbits and rats. lleal mucin flow was measured in weaned piglets fed diet based alone or mixed with chickpeas. It increased by 2.2 and 1.5-folds with white and black chickpeas, respectively. However, this did not reach significance due to high individual variation.

Published
2003

49. Enzymes in the small intestine of the calf: effect of dietary protein source on the activities of some enzymes in the small intestinal mucosa and digesta

Author

Montagne, Lucile, Salgado, Paulo, TOULLEC, R., Lalles, Jean Paul, Unité mixte de recherche veau et porc (UMR VP), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure Agronomique de Rennes, and ProdInra, Migration

Subjects
[SDV.IDA]Life Sciences [q-bio]/Food engineering, [SDV.IDA] Life Sciences [q-bio]/Food engineering, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2002

50. Enzymes of the small intestine of the calf : Effect of dietary protein source on the activities of some enzymes in the small intestinal mucosa and digesta

Author

Montagne, Lucile, Salgado, Paulo, Toullec, René, and Lallès, Jean-Paul

Subjects
animal structures, food and beverages, L73 - Maladies des animaux
Abstract

The objective of this study was to examine the effect of dietary protein source on the morphology and enzyme activities in the small intestinal mucosa and digesta of preruminant calves. The control diet contained skim milk powder. Plant proteins from soy concentrate (unhydrolysed or partially hydrolysed) and potato concentrate were incorporated into experimental diets. Duodenal, jejunal and ileal mucosal biopsies and digesta were collected from calves fitted with simple cannulae and continuously infused with milk replacers into the abomasum. Biopsies were used for morphology measurements. The activity of dipeptidylpeptidase IV, aminopeptidases, lactase and alkaline phosphatase was estimated in biopsies and digesta. Incorporating plant protein had a limited effect on the intestinal mucosa. A partial villus atrophy and crypt hyperplasia were noted with the soy concentrate only. Decreases in the activity of dipeptidylpeptidase IV with the potato concentrate diet and of aminopeptidase N and lactase with the hydrolysed soy concentrate diet, were also observed in ileal biopsies. Mucosal enzymes were released in the lumen and most of them accumulated in digesta of the distal small intestine. The activity of aminopeptidase N and lactase in ileal digesta was higher in calves fed the soy and potato concentrate diets than in those fed the control diet.

Published
2002

Catalog

Books, media, physical & digital resources
See catalog results