1. Mastering bioactive coatings of metal oxide nanoparticles and surfaces through phosphonate dendrons
- Author
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Philippe Lavalle, Da Shi, Emilie Voirin, Miriam Filippi, Geoffrey Cotin, Sylvie Begin-Colin, Marie Pierre Krafft, Delphine Felder-Flesch, Dinh-Vu Nguyen, Francis Perton, Arnaud Scherberich, Laura Power, Ludivine Hugoni, Institut Charles Sadron (ICS), Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Matériaux et nanosciences d'Alsace (FMNGE), and Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Langmuir ,Chemistry ,Nanoparticle ,02 engineering and technology ,General Chemistry ,Quartz crystal microbalance ,[CHIM.MATE]Chemical Sciences/Material chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Phosphonate ,Catalysis ,0104 chemical sciences ,Biofouling ,Metal ,chemistry.chemical_compound ,Chemical engineering ,visual_art ,Monolayer ,Materials Chemistry ,visual_art.visual_art_medium ,0210 nano-technology ,Iron oxide nanoparticles - Abstract
International audience; We reported herein an efficient method for constructing dendritic bisphosphonic acid tweezers of generations 1 and 2, which have been proven as versatile surface coatings for metal oxides implant or nanoparticles. These procedures delineated a practical and general route to a library of functional dendrons. Several of these dendritic architectures were successfully tested as biocompatible coverings for iron oxide nanoparticles through in vitro assays, but also as antifouling surface coatings for silica through Quartz Crystal Microbalance studies or as stabilizing structure for magnetic nanoparticles-microbubbles conjugates thanks to preliminary Langmuir monolayers studies.
- Published
- 2020