22 results on '"Keshavarz, Kambiz"'
Search Results
2. Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes
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Edraki, Mohammadreza, Nobakhti, Mohammadjavad, Naghshzan, Amir, Amoozgar, Hamid, Amirghofran, Ahmadali, Ghasemzadeh, Bahram, Nirooie, Elahe, Mehdizadegan, Nima, Mohammadi, Hamid, and Keshavarz, Kambiz
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- 2022
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3. Hidden pulmonary arteries in tetralogy of Fallot and pulmonary artery pressure in patients operated with a pulmonary artery
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Edraki, Mohammadreza, Ghasemzadeh, Bahram, Keshavarz, Kambiz, Amirghofran, Ahmadali, Mohammadi, Hamid, Kheirandish, Zahra, Amoozgar, Hamid, Nirooei, Elahe, Ajami, Gholamhossein, Mehdizadegan, Nima, Naghshzan, Amir, Peiravian, Farah, Cheriki, Sirous, and Nobahkti, Mohammad Javad
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- 2021
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4. Permanent longitudinal strain damage of cardiotoxic drugs in childhood cancer: What is the safe level?
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Mohammadi, Hamid, Hosseini, Hossein, Bordbar, Mohammadreza, Mehdizadegan, Nima, Amoozgar, Hamid, Edraki, Mohammad Reza, Naghshzan, Amir, Naderi, Nima, Abedi, Elham, and Keshavarz, Kambiz
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PATIENT safety ,SCIENTIFIC observation ,CANCER patients ,DESCRIPTIVE statistics ,DOSE-effect relationship in pharmacology ,CANCER chemotherapy ,DRUG monitoring ,LONGITUDINAL method ,CARDIOTOXICITY ,ANTHRACYCLINES ,CASE-control method ,COMPARATIVE studies ,ECHOCARDIOGRAPHY ,CHILDREN - Abstract
Objective : Anthracycline administration in children is associated with cardiac dysfunction. Speckle-tracking echocardiography (STE) can detect subclinical cardiac damage that may go undetected by conventional two-dimensional (2D) echocardiography. This study aims to investigate medium-term anthracycline cardiotoxicity using STE and determine a safer administrable level of anthracyclines (ACs). Methods : This observational case-control study enrolled 37 healthy controls and 78 pediatric cancer survivors who received chemotherapy. The patients were divided into two groups: cardiotoxic received (CR) and cardiotoxic free (CF). Data on segmental longitudinal strain (LS), global LS (GLS), and 2D echocardiographic parameters were collected after a drug-free period of at least one year. Results : A total of 115 children with a mean age of 108 ± 55 months, of whom 66% were males, were included in the study. Both the groups of cancer survivors exhibited significantly reduced GLS compared to healthy controls (CR vs. controls, P = 0.001; CF vs. controls, P = 0.013), but no significant difference in left ventricular ejection fraction (LVEF) was observed (P = 0.75). Overall, cancer survivors treated with ACs demonstrated a significant reduction in strain in 10 left ventricular segments, particularly in the basal segments (P < 0.05). Among CR patients, those with impaired GLS (n = 43, GLS worse than -21.9) had significantly higher mean age and cumulative anthracycline dose compared to CR patients with normal GLS (age, P = 0.024; anthracycline dosage, P = 0.036). Using an anthracycline cutoff of 223 mg/m² resulted in a higher detection rate (49% vs. 25%) and fewer missed cases (51% vs. 74%) compared to the 360 mg/m² anthracycline cutoff. Conclusion : Childhood cancer survivors demonstrate significantly reduced GLS while preserving a normal LVEF, which does not differ significantly from reference values of healthy children. The reduction in strain appears to be associated with higher anthracycline doses and older age. Lowering the anthracycline threshold to 223 mg/m² may improve the predictability of a decline in cardiac function using strain imaging at medium-term follow-up. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Hemolysis and its outcome following percutaneous closure of cardiac defects among children and adolescents: a prospective study
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Amoozgar, Hamid, Soltani, Romeileh, Edraki, Mohammadreza, Mehdizadegan, Nima, Mohammadi, Hamid, Ajami, Gholamhossein, Borzouee, Mohammad, Naghshzan, Amir, and Keshavarz, Kambiz
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- 2019
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6. Ductus Arteriosus Stenting in Neonates with Pulmonary Valve Atresia: Outcomes and Considerations.
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Edraki, Mohammadreza, Jouhari, Leila, Naghshzan, Amir, Amoozgar, Hamid, Mohammadi, Hamid, Ajami, Gholam Hossein, Mehdizadegan, Nima, Keshavarz, Kambiz, and GhasemZadeh, Bahram
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CARDIAC surgery ,PULMONARY atresia ,PATENT ductus arteriosus ,PULMONARY circulation ,SURGICAL stents ,RETROSPECTIVE studies ,ACQUISITION of data ,OXYGEN saturation ,TREATMENT effectiveness ,MEDICAL records ,DESCRIPTIVE statistics ,VENTRICULAR septal defects ,EVALUATION - Abstract
Background: Patent ductus arteriosus (PDA) stenting was invented particularly for congenital heart diseases with ductaldependent pulmonary blood flow, and newer techniques are constantly being introduced. Objectives: In this study, we investigate the one-year results of this procedure and describe some of our periprocedural considerations. Methods: The neonates with pulmonary atresia and ventricular septal defect (VSD)whounderwent PDA stenting in our center from February 2016 to December 2019 were included in this retrospective study. Spo2 and McGoon ratios were recorded before and a year after stenting and compared to each other. Results: In 26 neonates, PDA stenting was performed; 20 procedures (77%) were successful, and six procedures (23%) were unsuccessful. Two of these unsuccessful cases died during the procedure, and two of them died as a result of neonatal sepsis following the procedure. A total of 18 PDAs (70%) were accessed via the axillary artery, 6 (23%) via the femoral artery, and 2 (7%) via the antegrade inferior vena cava route. The comparison between the results before and one year after stenting revealed the increase of O2 saturation from 53.78±7.35 to 84.33±6.5 (P-value = 0.032) and McGoon ratio from 1.16±0.25 to 1.65±0.34 (P-value = 0.041). Additionally, we discussed some technical considerations of PDA stenting, including the access point, management of pulmonary artery bifurcation stenosis, stent diameter, stenting of long and tortuous PDAs, thrombosis, and anticoagulation. Conclusions: Ductal stenting increases SpO2 and McGoon ratio and could be a less-invasive option for securing pulmonary blood circulation. However, further studies are required to advance PDA stenting techniques for specific anatomical features. [ABSTRACT FROM AUTHOR]
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- 2022
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7. Speckle Tracking Echocardiography before and after Surgical Pulmonary Valve Replacement in Tetralogy of Fallot Patients: Can STE Elucidate Early Left Ventricular Dysfunction?
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Ajami, Gholamhossein, Alvasabi, Fathi, Mehdizadegan, Nima, Edraki, Mohammadreza, Mohammadi, Hamid, Amirghofran, Ahmad Ali, Ghasemzade, Bahram, Keshavarz, Kambiz, Amoozgar, Hamid, Arabi, Hamid, Naghshzan, Amir, Borzoee, Mohammad, and Peiravian, Farah
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HEART ventricle diseases ,ECHOCARDIOGRAPHY ,LEFT heart ventricle ,SCIENTIFIC observation ,SURGICAL complications ,TETRALOGY of Fallot ,PULMONARY valve ,CROSS-sectional method ,EARLY diagnosis ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Background: Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Most studies have focused on Right Ventricular (RV) dysfunction, while the left ventricle has received less attention in patients with TOF. Objectives: This study aimed to investigate the Left Ventricular (LV) function after surgical Pulmonary Valve Replacement (sPVR) in patients with repaired TOF (rTOF) by Speckle Tracking Echocardiography (STE). Methods: This single-center, observational, cross-sectional study was conducted on 58 volunteers (age: 15 - 31 years) divided into three groups as follows: 22 PVR patients (mean age: 18.96 ± 7 year), 16 patients with rTOF, and 20 healthy controls who were matched regarding the PVR age range. 2D echocardiography (including Doppler and M-Mode indices of the right and left ventricles) and Speckle Tracking Echocardiography (STE) (Global Longitudinal Strains (GLS) and 18 segment analyses) were performed for all patients. All analyses were done using the SPSS software and P < 0.05 was considered to be statistically significant. Results: 2D echocardiography showed normal LV Ejection Fraction (LVEF) in all study groups (64% in sPVR, 60% in rTOF (P = 0.127), and 62.5% in the control group). However, the mean GLS of the left ventricle significantly reduced in both sPVR (-17.5 ± 2.5%) and rTOF (-17.1 ± 4.7%) patients in comparison to the control group (-20.2 ± 0.7%) (P = 0.003). Yet, no significant difference was observed between the rTOF and sPVR groups regarding the GLS (P = 0.9). Segmental analysis of the Longitudinal Strain (LS) indicated a significant decrease in the sPVR and rTOF groups in basal anterior, basal septal, basal anterolateral, mid-anterior, and anterolateral segments. Except for the lower LS in the apical-anteroseptal segment, this level was mostly spared in both sPVR and rTOF patients. Conclusion: LVEF was within the normal range among the sPVR patients, but the pattern of impaired segmental LS and GLS did not change compared to the rTOF group. In conclusion, sPVR might not have a significant effect on the improvement of LV function assessed by STE in patients with rTOF. LV damage occurring during the surgical correction of TOF might have a permanent deteriorating effect on LV function. [ABSTRACT FROM AUTHOR]
- Published
- 2020
8. Effect of Celox® Powder on Initial Hemostasis After Cardiac Catheterization in Pediatric Patients with Congenital Heart Disease: A Prospective Study.
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Amoozgar, Hamid, Abtahi, Saeed, Edraki, Mohammad Reza, Mohammadi, Hamid, Ajami, Gholam Hossein, Mehdizadegan, Nima, Keshavarz, Kambiz, Moradi, Pouria, Shabanpuor-Haghighi, Sajad, and Zafari, Tahmineh
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CARDIAC catheterization in children ,CLOTHING & dress ,CONGENITAL heart disease ,HEMOSTASIS ,LONGITUDINAL method ,VENOUS puncture - Abstract
Background: Ordinary pressure dressing for hemostasis after cardiac catheterization is time consuming and might cause some problems, such as pain or loss of blood, which has to be controlled, particularly in pediatric patient. Using Celox® (chitosan) powder dressing might cause quicker initial hemostasis. Methods: In this prospective study, we assessed Celox® powder among patients in hospitals affiliated with Shiraz University of Medical Sciences, fromNovember2017 to February 2018. The patients were stratified in two groups. The case group included patients for whom Celox® powder was used along with sterile gauze pressure at the puncture site to achieve hemostasis, and the control group those in whom hemostasis was achieved by standard sterile gauze pressure method. Results: Sixty patients under 16 years of age with congenital heart diseases were evaluated and underwent cardiac catheterization. We stratified the patients in two groups called case (30 patients) and control group (30 patients). Considering both arterial and venous initial hemostasis, in the case group, the minimum and maximum, median and mean coagulation time were less than those in the control group; however, the initial hemostasis was statistically significant only in venipuncture site. Also, the venous coagulation time was shorter among the patients weighing less than 10 kilograms in comparison to those with higher weight. In the case group, using Celox® stirred hemostasis toward the lower percentiles, but based on 50th percentile, the distribution in each group was identical. Conclusions: Celox® powder dressing in children led to reduced coagulation time in venipuncture site, and we might recommend utilizing this type of dressing for venous hemostasis in children after venipuncture. [ABSTRACT FROM AUTHOR]
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- 2020
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9. Arterial and Venous Complications Early After Cardiac Catheterization in Children and Adolescents: A Prospective Study.
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Amoozgar, Hamid, Naghshzan, Amir, Edraki, Mohammad Reza, Jafari, Hamed, Ajami, Gholam Hossein, Mohammadi, Hamid, Mehdizadegan, Nima, Borzouee, Mohammad, and Keshavarz, Kambiz
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ARTERIAL injuries ,CORONARY heart disease risk factors ,VENOUS thrombosis risk factors ,INJURY risk factors ,VASCULAR diseases ,BODY weight ,CARDIAC catheterization ,FEMORAL artery ,FISTULA ,LONGITUDINAL method ,PEDIATRICS ,RISK assessment ,SURGICAL complications ,VEINS ,DISEASE incidence ,DISEASE prevalence ,ARTERIAL dissections ,FALSE aneurysms ,AXILLARY artery ,DISEASE risk factors - Published
- 2019
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10. Early Post-Operative Arrhythmias and Their Risk Factors after Total Repair of Tetralogy of Fallot in Pediatric Patients.
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Edraki, Mohammadreza, Sadeghi, Maryam, Keshavarz, Kambiz, and Mehdizadegan, Nima
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ARRHYTHMIA ,SUPRAVENTRICULAR tachycardia ,AGE distribution ,BUNDLE-branch block ,ELECTROCARDIOGRAPHY ,CARDIAC surgery ,MILRINONE ,PULMONARY stenosis ,SURGICAL complications ,TETRALOGY of Fallot ,RETROSPECTIVE studies ,DISEASE risk factors - Abstract
Background: Conduction disturbances can occur early after total correction of Tetralogy of Fallot (TOF). Some of these arrhythmias and alterations like complete right bundle branch block are permanent, while some others like Junctional Ectopic Tachycardia (JET) are transient. Objective: This study aimed to evaluate the early post-operative arrhythmias and their risk factors among pediatric patients with TOF after surgical total correction. Methods: This retrospective study was conducted on pediatric patients aged six months to 15 years old (52.5% male and 47.5% female) with TOF who had consecutively underwent surgical total correction during 2015 - 2017. Patients with additional concomitant cardiac operations, previous arrhythmias before the surgery, or any co-existing cardiac anomalies as well as those with severe post-operative complications were excluded. All pertinent data and Electrocardiographic (ECG) documents were recorded several times right after the operation to detect arrhythmias and ECG changes and to find any association between the related risk factors and the occurrence of arrhythmias. Results: Out of the 118 TOF patients who underwent total correction, 27% were under the age of one year and 73% were above one year old. Among the patients, 78.5% developed permanent ECG changes, mostly complete right bundle branch block and left anterior or posterior hemiblock. Out of these patients, 8.5% had JET together with other permanent arrhythmias and 8.5% had transient JET solely. Therefore 17% of all patients developed JET and 21.5% had no permanent noticeable ECG changes. The most permanent arrhythmia was right bundle branch block followed by left anterior hemiblock and left posterior hemiblock. These arrhythmias mainly manifesed amongst the patients with lower age and those with severe subvalvar pulmonary stenosis. The results showed a significant relationship between the incidence of JET and use of milrinon after the operation. There was no myocardial ischemia or infarction from injury to aberrant coronary arteries passing over the right ventricular outflow tract. Conclusion: Early post-operative permanent arrhythmias after total TOF repair was probably more common amongst the patients who were below one year old with more severe subvalvar pulmonary stenosis. Nonetheless, the occurrence of transient JET was mostly observed in the patients who were given milrinone as a post-operative inotrope medicine. [ABSTRACT FROM AUTHOR]
- Published
- 2019
11. A Study of Intracoronary Injection of Hematopoietic Stem Cells in Pediatric Dilated Cardiomyopathy: Is It an Applicable Solution for Critically Ill Patients?
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Amoozgar, Hamid, Edraki, Mohammad R., Ayatollahi, Maryam, Borzouee, Mohammad, Ajami, Gholamhossein, Mohammadi, Hamid, Mehdizadegan, Nima, Shakibazad, Nader, Arabi, Hamid, Alwesabi, Fatehi, Naghshzan, Amir, and Keshavarz, Kambiz
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CRITICALLY ill ,ECHOCARDIOGRAPHY ,HEART physiology ,HEART ventricles ,HEMATOPOIETIC stem cell transplantation ,INTRA-arterial injections ,PATIENTS ,TREATMENT effectiveness ,DILATED cardiomyopathy ,VENTRICULAR ejection fraction ,EVALUATION ,CHILDREN - Abstract
Background: Benefits of stem cell therapy on remodelling and cardiac function have been described in adults with dilated cardiomyopathy and acute myocardial infarction. Objectives: We investigated the effect of this treatment modality amongst children with severe dilated cardiomyopathy. Methods: Intracoronary injection of autologous bone marrow mononuclear stem cells was performed in our centers for 8 severely ill children during 2015 - 2016. Themeanage of the patients was 10.1 years (5 girls, 3 boys). They were followed by longitudinal speckle tracking echocardiography (STE) and conventional echocardiography for 6 months. Results: Heart functional class improved in 62% of patients. M-mode echocardiography showed significant improvement in ejection fraction (mean 24.8±8.3 vs. 37.4±10.5) and in STE, the mean global longitudinal strain improved (GLS: -2.8±1.9 vs. -5.2±3.9). None of the patients had serious complications. Conclusions: Intracoronary injection of autologous mononuclear stem cells might improve the ventricular function and cardiac remodelling in pediatric patients with dilated cardiomyopathy and could be considered in critically ill patients. [ABSTRACT FROM AUTHOR]
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- 2019
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12. Efficacy of High Dose and Short Course of Deferoxamine Infusion on Cardiac Remodeling 0f Children with Thalassemia Major.
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Shahryari, Mehdi, Mehdizadegan, Nima, Amoozgar, Hamid, Borzouee, Mohammad, Ajami, Gholamhossein, Cheriki, Sirous, Edraki, Mohammad Reza, Shakiba, Ali Mohammad, Mohammadi, Hamid, and Keshavarz, Kambiz
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DEFEROXAMINE ,ECHOCARDIOGRAPHY ,FERRITIN ,HEART function tests ,INTRAVENOUS therapy ,LONGITUDINAL method ,MITRAL valve ,CARDIOMYOPATHIES ,RISK assessment ,VENTRICULAR remodeling ,TREATMENT effectiveness ,EARLY diagnosis ,BETA-Thalassemia ,VENTRICULAR ejection fraction ,DISEASE risk factors - Abstract
Background: Speckle tracking echocardiography has great value in evaluation of regional and global myocardial function. Objectives: The goal of this study was an assessment of cardiac function and remodeling in children with thalassemia major after infusion of a high dose of deferoxamine during a short course by speckle echocardiography and evaluate the efficacy of this imaging modalities in the early recognition of recovering of myocardial dysfunction. Methods: In a prospective study between Feb 2014 till 2017 conventional 2 dimensional and speckle tracking echocardiography were done consecutively on 21 patients with beta-thalassemia major before intravenous infusion of high dose of deferoxamine (50 mg/kg) for 5 days and then after 3 months echocardiographic measurements repeated for assessment of efficacy of deferoxamine infusion on ventricular function and cardiac remodeling of our study population. Results: Serum ferritin of all patients reduced significantly (P < 0.001). Ejection fraction was improved after the therapy (P < 0.001). Mitral E/A velocity ratio after therapy increased significantly (P < 0.001). Strain imaging measures showed an increase in apical lateral, mid-lateral, basal lateral, mid-septal, basal septal left ventricular longitudinal wall strain three months after the use of high dose deferoxamine (P < 0.001). Apico-septal wall strain measurements of the left ventricle did not change significantly after high dose deferoxamine (P = 0.144). Conclusions: Intravenous infusion of high dose of deferoxamine after chelating of iron results in reduction of serum ferritin which may cause washout of cardiac deposit of iron with consequent improvement of cardiac function and remodeling. [ABSTRACT FROM AUTHOR]
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- 2019
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13. Is There Any Correlation Between Two and Three Dimensional Echocardiography in Ductal Dimensions with Angiography?
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Borzouee, Mohammad, Arabi, Hamid, Ajami, Gholam Hossein, Amoozgar, Hamid, Edraki, Mohammad Reza, Mehdizadegan, Nima, Mohammadi, Hamid, Alvasabi, Fathi, Naghshzan, Amir, and Keshavarz, Kambiz
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ACADEMIC medical centers ,ANGIOGRAPHY ,BODY weight ,CATHETERIZATION ,COMPARATIVE studies ,ECHOCARDIOGRAPHY ,MEDICAL referrals ,PATENT ductus arteriosus ,PEDIATRICS ,ELECTIVE surgery ,DIAGNOSIS - Abstract
Background: The aim of this study was to determine if there is any correlation between patent ductus arteriosus (PDA) dimensions measured by two dimensional echocardiography (2DE) and three dimensional echocardiography (3DE) in comparison with angiographic data as the gold standard technique. Such correlation may help us to immediately detect ductal spasm and select the proper device according to echocardiographic assessments. Methods: In this comparative study, we successively selected 26 pediatric patients with isolated PDA, who referred for elective percutaneous PDA closure at Nemazee Hospital, affiliated to Shiraz University of Medical Sciences (SUMS) since January 2016 till March 2017. All patients underwent full 2DE and 3DE before device closure at the day of angiography (less than 5 hours before catheterization). We emphasized the dimension of pulmonic and aortic end diameter and length of PDA by these modalities and comparison of our data. Results: The study population had a mean age of 28.7 months and a mean weight of 10.67 Kg; the majority of our patients were female (84.6%). The difference in pulmonic end of PDA was not significant statistically by all modalities. The difference in aortic end of PDA was significant and there was no correlation between 2DE and 3DE with angiographic data. Comparison of data obtained from 2DE and 3DE revealed that the length of PDA in 2DE, 3DE angiography well correlated with each other. One case developed ductal spasm during angiography. Conclusions: The ductus pulmonic end and length dimensions measured by echocardiography and angiography well correlated with each other and were interchangeable. Such findings may be helpful during percutaneous transcatheter occlusion if any ductal spasm happens. Thus, we may recommend the use of a suitable device according to the maximum size of PDA that was measured either by echocardiography or angiographic studies. [ABSTRACT FROM AUTHOR]
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- 2018
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14. Heart Function and Remodeling after Successful Balloon Valvuloplasty for Congenital Aortic Stenosis in Children.
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Amoozgar, Hamid, Mohammadi, Hamid, Shahrivar, Farid, Borzoee, Mohammad, Ajami, Gholamhossein, Edraki, Mohammadreza, Mehdizadegan, Nima, and Keshavarz, Kambiz
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HEART physiology ,AORTIC stenosis treatment ,CATHETERIZATION ,CONGENITAL heart disease ,ECHOCARDIOGRAPHY ,CARDIAC patients ,MEDICAL needs assessment ,VENTRICULAR remodeling ,TREATMENT effectiveness ,PATIENT selection - Abstract
Background: Congenital Aortic Stenosis (AS) is a common problem among congenital heart diseases and balloon valvuloplasty is known as the procedure of choice for treatment. Objectives: This study aimed at evaluation of the function and remodeling of the heart after a successful balloon AS valvuloplasty. Patients and Methods: From September 2012 to 2016, 33 patients with congenital AS who had successful balloon valvuloplasty were enrolled into this study. All patients were evaluated by 2D, M-mode, Doppler, and tissue Doppler echocardiography before and after the procedure. The data were analyzed using the SPSS statistical software. Results: The median duration of follow-up was 2 years (range = 6 months to 7.4 years). Besides, the mean of immediate peak-to-peak gradient reduction was 41.50 ± 17.36 mmHg. Moderate to severe aortic insufficiency occurred in less than 28% of the patients. Additionally, M-mode echocardiography showed residual left ventricular hypertrophy in 50% of the patients. Moreover, E/A ratio was less than -2 Z-scores in 73% of the patients. E/Ea ratio was also more than 2 Z-scores in 50% of the patients, which was an indicator of diastolic dysfunction. The most common associated lesion was bicuspid aortic valve in 48% of the cases. Conclusions: Balloon aortic valvuloplasty effectively reduced peak systolic pressure gradient across the aortic valve in patients with congenital AS although left ventricular hypertrophy and diastolic dysfunction persisted in a significant number of patients. [ABSTRACT FROM AUTHOR]
- Published
- 2018
15. The prevalence of visual disorders in Iranian students: A meta-analysis study and systematic review.
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Keshavarz, Kambiz, Angha, Parvin, Sayehmiri, Fatemeh, Sayemiri, Kourosh, and Yasemi, Masood
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CONFIDENCE intervals , *MEDLINE , *META-analysis , *ONLINE information services , *STUDENTS , *VISION disorders , *SYSTEMATIC reviews , *DISEASE prevalence , *DATA analysis software , *DESCRIPTIVE statistics - Abstract
Background: Visual defects have dramatic effects on health, self-esteem, and educational function of students, and delayed diagnosis will cause complications, like academic failure and psychologic disorders. Objective: The present study aimed to investigate the prevalence of ocular disorders in Iranian students in a systematic review. Methods: We searched databases, including PubMed, SID, Magiran, Google Scholar, and Iranmedex using the following keywords in Persian and English: disorders, vision, amblyopia, refractive errors, astigmatism, student, and Iran with all the possible combinations, important, chief, and sensitive words. Search resulted in 28 articles, conducted during a period from 1996 to 2014 in Iran and their data was analyzed using meta-analysis and random effects model. Heterogeneity of studies was assessed using I2 index, and data was finally analyzed with R Software and STATA (Version 11.2). Results: Total number of subjects in the study was 1,117,274, aged 2 to 18 years. The prevalence of disorders related to amblyopia, refractive error, and strabismus was 8%, 7% and 1%, respectively. The greatest amount of refractive error was related to astigmatism (19%) followed by myopia (17%). Conclusion: According to the study results, the prevalence of visual disorders among Iranian students indicated the critical necessity of screening programs for prevention of visual disorders in this age group. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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16. Giant Hydronephrosis Due to Congenital Uretropelvic Junction Obstruction, a Report of 2 cases.
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Sadeghi-Bojd, Simin, Fazeli, Faramarz, Keshavarz, Kambiz, and Baktash, Maryam
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HYDRONEPHROSIS in children ,URETERIC obstruction ,UROLOGICAL surgery ,CONGENITAL disorders ,KIDNEY radiography - Abstract
Ureteropelvic junction (UPJ) stenosis occurs in 13% of children. Antenatally, the diagnosis is possible by showing renal pelvis dilatation by obstetric ultrasonography. Giant hydronephrosis (GH) is a rare condition. There are different etiologies for GH which are mostly congenital and occur during infancy and childhood. GH was confirmed by complementary evaluations in a 2-month-old female infant with poor feeding, lethargy, and vomiting together with an antenatal sonography in favor of hydronephrosis, and a 5-year-old boy with an abdominal mass diagnosed by sonography following 2 weeks of progressive abdominal distention. Pyeloplasty was associated with an excellent result in both of them. [ABSTRACT FROM AUTHOR]
- Published
- 2014
17. Urine β 2-Microglobolin in the Patients with Congenital Heart Disease.
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Noori, Noor Mohammad, Sadeghi, Simin, Shahramian, Iraj, and Keshavarz, Kambiz
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CONGENITAL heart disease diagnosis ,INBORN errors of metabolism diagnosis ,URINE ,RENAL tubular transport disorders ,ACADEMIC medical centers ,CARDIOLOGY ,KIDNEY diseases ,MEDICAL care ,PATIENTS ,PEDIATRICS ,PROTEINS ,URINALYSIS ,CONTROL groups ,CASE-control method ,DISEASE complications ,PHYSIOLOGY ,DIAGNOSIS - Abstract
Background: This study aimed to evaluate the renal tubular function in the patients with congenital heart disease using β²-microglobulin. Methods: In this case-control study, based on oxymetry, the patients with congenital heart disease were divided into two groups of cyanotic (n=20) and acyanotic (n=20). Congenital heart disease was diagnosed by echocardiography. Healthy individuals within the same age and sex groups were used as controls. Na
+ , β²-micro globulin, creatinine (Cr), and β²-microglobulin/Cr ratio were measured in random urine samples and the results were compared to the same parameters in the control group using Tukey, One-Way ANOVA, and X² tests. Results: Based on the study results, urine sodium in the patients with cyanotic heart disease was significantly different from that of the controls (P=0.023). The results also revealed a significant difference between the two groups with congenital heart disease regarding urine β²-microglobulin (P=0.045). In addition, the patients with cyanotic heart disease were significantly different from those with acyanotic heart disease and the controls regarding urine β²-micro globulin/Cr ratio (P=0.012 and P=0.026, respectively). Conclusions: The results of this study demonstrated that renal tubular dysfunction began in the patients with congenital heart disease, especially in those with cyanotic congenital heart disease. Besides, early diagnosis before cardiac surgery leads to better control of renal tubular disease. [ABSTRACT FROM AUTHOR]- Published
- 2013
18. Comparison of Right and Left Side Heart Functions in Patients with Thalassemia Major, Patients with Thalassemia Intermedia, and Control Group.
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Noori, Noormohammad, Mohamadi, Medhi, Keshavarz, Kambiz, Mostafa Alavi, Seyed, Mahjoubifard, Maziar, and Mirmesdagh, Yalda
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HEART physiology ,ANALYSIS of variance ,ECHOCARDIOGRAPHY ,HEART diseases ,HEART function tests ,STATISTICS ,T-test (Statistics) ,THALASSEMIA ,DATA analysis ,CASE-control method ,BETA-Thalassemia - Abstract
Background: Heart disease is the main cause of mortality and morbidity in patients with beta thalassemia, rendering its early diagnosis vital. We studied and compared echocardiographic findings in patients with beta thalassemia major, patients with beta thalassemia intermedia, and a control group. Methods: Eighty asymptomatic patients with thalassemia major and 22 asymptomatic cases with thalassemia intermedia (8-25 years old) were selected from those referred to Ali Asghar Hospital (Zahedan-Iran) between June 2008 and June 2009. Additionally, 80 healthy individuals within the same age and sex groups were used as controls. All the individuals underwent echocardiography, the data of which were analyzed with the Student t-test. Results: The mean value of the pre-ejection period/ejection time ratio of the left ventricle during systole, the diameter of the posterior wall of the left ventricle during diastole, the left and right isovolumic relaxation times, and the right myocardial performance index in the patients with beta thalassemia major and intermedia increased significantly compared to those of the controls, but the other parameters were similar between the two patient groups. The mean values of the left and right pre- ejection periods, left ventricular end systolic dimension, and left isovolumic contraction time in the patients with thalassemia intermedia increased significantly compared to those of the controls. In the left side, myocardial performance index, left ventricular mass index, isovolumic contraction time, and deceleration time exhibited significant changes between the patients with thalassemia major and those with thalassemia intermedia, whereas all the echocardiographic parameters of the right side were similar between these two groups. Conclusion: The results showed that the systolic and diastolic functions of the right and left sides of the heart would be impaired in patients with thalassemia major and thalassemia intermedia. Consequently, serial echocardiography is suggested in asymptomatic patients with beta thalassemia for an early diagnosis of heart dysfunction and proper treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2013
19. Cardiac and pulmonary dysfunction in asymptomatic beta-thalassanemia major.
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Noori, Noor Mohammad, Keshavarz, Kambiz, and Shahriar, Mosaeib
- Abstract
This study assessed cardiac and pulmonary dysfunction in 26 asymptomatic patients with beta-thalassemia major. This investigation was a case-controlled study considering 10-20-year-old patients with beta-thalassemia major and no cardiac or pulmonary symptoms. Healthy individuals matched for age and sex were used as controls. At 48-72 h after blood transfusion, the patients underwent echocardiography and spirometry by a cardiologist and a pulmonologist. The results were compared to those of the control group. The right and left myocardial performance index, preejection period/ ejection time ratio, ejection fraction, acceleration time, isovolumic contraction time, and bilateral isovolumic relaxation times in the study group demonstrated significant differences from the data of the controls. Right deceleration time was significantly different between the 2 groups. Myocardial performance index, peak early velocity of the right heart, and peak atrial velocity-to-peak early velocity ratio of the right side by Doppler tissue imaging were also significantly different between the 2 groups. Spirometry showed a significant difference in forced expiratory volume in I s/forced vital capacity between groups. Based on spirometry, pulmonary involvement in the patients was 77% restrictive. These findings show that systolic and diastolic dysfunction of the heart and pulmonary disturbances are unavoidable in patients with betathalassemia major. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
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20. Japanese Kawasaki Disease Scoring Systems: Are they Applicable to the Iranian Population?
- Author
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Edraki, Mohammad Reza, Mohammadi, Hamid, Mehdizadegan, Nima, Ghorashi, Mojtaba, Amoozgar, Hamid, Borzouee, Mohammad, Ajami, Gholamhossein, Keshavarz, Kambiz, Dehghani, Elham, and Bahrami, Reza
- Subjects
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ANEURYSM diagnosis , *CORONARY heart disease risk factors , *MUCOCUTANEOUS lymph node syndrome diagnosis , *AGE distribution , *ANEURYSMS , *CONFIDENCE intervals , *CORONARY disease , *DRUG resistance , *ECHOCARDIOGRAPHY , *IMMUNOGLOBULINS , *INTRAVENOUS therapy , *MEDICAL screening , *MUCOCUTANEOUS lymph node syndrome , *RISK assessment , *HUMAN research subjects , *CROSS-sectional method , *RETROSPECTIVE studies , *PATIENT selection , *DISEASE complications - Abstract
Background: Kawasaki disease (KD) is the most frequent cause of coronary artery aneurysm (CAA) in children. This study tried to evaluate the accuracy of different KD scores developed for prediction of CAA, in an Iranian population. Methods: This is a cross-sectional retrospective investigation on pediatric patients with a diagnosis of KD. Clinical manifestations, laboratory, and echocardiographic data were recorded. Five Kawasaki scores, including Kobayashi, Egami, Sano, Nakano, and Harada, were assessed and analyzed in relation to CAA and intravenous immunoglobulin (IVIG) resistance. Results: During five years, we recruited 121 cases of KD under 13 years of age. The rates of CAA and IVIG resistance were 16.5%, and 13.2% respectively. The IVIG resistance group was significantly younger than responder patients. All five scores had low sensitivity in predicting CAA or IVIG resistant cases; the highest sensitivity pertained to the Harada score with 50% sensitivity and 59% specificity (the area under the curve: 0.545, with a 95% confidence interval: 0.423 to 0.667) in predicting CAA, which is lower than the usual acceptable criteria for a screening test. The specificity of all other scores were more than 85% in predicting CAA or IVIG resistance. Gender, fever before therapy and laboratory data showed no significant difference between the groups. Conclusion: The Kobayashi, Egami, Sano, Nakano and Harada scores have limited usefulness in the Iranian population to predict high risk patients for coronary artery involvement or IVIG resistance; in our study, age under one year was a risk factor for IVIG resistance. [ABSTRACT FROM AUTHOR]
- Published
- 2020
21. Timing percutaneous coronary interventions and cardiovascular events in non-ST-elevation myocardial infarction patients.
- Author
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Hemmati R, Fathi M, Heidarian Moghadam M, Mohebbi B, Keshavarz K, Mohebbi A, and Rahmani A
- Abstract
Background: The timing of coronary angiography in patients with non-ST elevation myocardial infarction (NSTEMI) needs to be well defined. In this study, based on the timing of percutaneous coronary intervention (PCI), we evaluated the incidence of major adverse cardiovascular events (MACE) in NSTEMI patients., Methods: In this longitudinal study, we included 156 NSTEMI patients who underwent a PCI at three time points, including <12 hr. (n = 53), 12-24 hr. (n = 54), and ≥24 hr. (n = 49) and followed them for one, three, and six months to monitor major cardiovascular events. The data analyses were conducted using SPSS version 20., Result: Four patients (2.56%) were hospitalized during the one-month follow-up, and only one patient (0.06%) had NSTEMI. The incidence of complications, such as readmission, acute coronary syndrome (ACS; 4 patients [2.56%]), and unstable angina (UA; 3 patients [1.92%]) did not differ significantly among the three intervention times. The occurrence of NSTEMI, UA, and recurrent PCI was 2.56%, 3.20%, and 5.12% in four, five, and eight patients, respectively, and no significant differences were observed among the aforementioned times. In the follow-up after six months, the incidence of STEMI, stroke, TLR, and other all-course deaths was observed in one person (0.06%), which all occurred within 12-24 hours. The difference among the three intervention times was non-significant., Conclusion: Our findings revealed an insignificant difference between the incidence of complications and the three-intervention time., Competing Interests: None., (AJCD Copyright © 2024.)
- Published
- 2024
22. Comparison of right and left side heart functions in patients with thalassemia major, patients with thalassemia intermedia, and control group.
- Author
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Noori N, Mohamadi M, Keshavarz K, Alavi SM, Mahjoubifard M, and Mirmesdagh Y
- Abstract
Background: Heart disease is the main cause of mortality and morbidity in patients with beta thalassemia, rendering its early diagnosis vital. We studied and compared echocardiographic findings in patients with beta thalassemia major, patients with beta thalassemia intermedia, and a control group., Methods: Eighty asymptomatic patients with thalassemia major and 22 asymptomatic cases with thalassemia intermedia (8-25 years old) were selected from those referred to Ali Asghar Hospital (Zahedan-Iran) between June 2008 and June 2009. Additionally, 80 healthy individuals within the same age and sex groups were used as controls. All the individuals underwent echocardiography, the data of which were analyzed with the Student t-test., Results: The mean value of the pre-ejection period/ejection time ratio of the left ventricle during systole, the diameter of the posterior wall of the left ventricle during diastole, the left and right isovolumic relaxation times, and the right myocardial performance index in the patients with beta thalassemia major and intermedia increased significantly compared to those of the controls, but the other parameters were similar between the two patient groups. The mean values of the left and right pre-ejection periods, left ventricular end systolic dimension, and left isovolumic contraction time in the patients with thalassemia intermedia increased significantly compared to those of the controls. In the left side, myocardial performance index, left ventricular mass index, isovolumic contraction time, and deceleration time exhibited significant changes between the patients with thalassemia major and those with thalassemia intermedia, whereas all the echocardiographic parameters of the right side were similar between these two groups., Conclusion: The results showed that the systolic and diastolic functions of the right and left sides of the heart would be impaired in patients with thalassemia major and thalassemia intermedia. Consequently, serial echocardiography is suggested in asymptomatic patients with beta thalassemia for an early diagnosis of heart dysfunction and proper treatment.
- Published
- 2013
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