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1. Immunohistochemical Detection of JC Virus in Nontumorous Renal Tissue of a Patient with Renal Cancer but without Progressive Multifocal Leukoencephalopathy

Author

Nobutaka Fukumori, Yosimitsu Sakamoto, Naoto Aoki, Kenzo Kato, Tadaichi Kitamura, Mayumi Mori, and Takashi Tominaga

Subjects
Microbiology (medical), Male, Pathology, medicine.medical_specialty, Encephalopathy, JC virus, medicine.disease_cause, urologic and male genital diseases, Antibodies, Viral, Kidney, Virology, medicine, Humans, Kidney Tubules, Collecting, Microscopy, Immunoelectron, biology, business.industry, Progressive multifocal leukoencephalopathy, Leukoencephalopathy, Progressive Multifocal, Cancer, Middle Aged, medicine.disease, Immunohistochemistry, JC Virus, Kidney Neoplasms, Tumor Virus Infections, medicine.anatomical_structure, biology.protein, Antibody, business, Kidney disease
Abstract

We performed immunohistochemical staining on the nontumorous renal tissue of 45 patients with renal cancer but without progressive multifocal encephalopathy using JCV-specific antibody. For one patient we found positive staining of the nuclei of the renal collecting ducts. Immunoelectron microscopic examination of the positive cell nuclei revealed electron-dense polyomavirus-like particles.

Published
1999

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