Immunohistochemical Detection of JC Virus in Nontumorous Renal Tissue of a Patient with Renal Cancer but without Progressive Multifocal Leukoencephalopathy

Authors :: Nobutaka Fukumori
Yosimitsu Sakamoto
Naoto Aoki
Kenzo Kato
Tadaichi Kitamura
Mayumi Mori
Takashi Tominaga
Publication Year :: 1999
Publisher :: American Society for Microbiology, 1999.
Abstract: We performed immunohistochemical staining on the nontumorous renal tissue of 45 patients with renal cancer but without progressive multifocal encephalopathy using JCV-specific antibody. For one patient we found positive staining of the nuclei of the renal collecting ducts. Immunoelectron microscopic examination of the positive cell nuclei revealed electron-dense polyomavirus-like particles.

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