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Very early-onset schizophrenia (defined as an onset of psychosis before 13 years of age) is a rare and severe form of the disorder which is clinically and neurobiologically continuous with the adult-onset disorder. It is rarely reported <12 years of age in Indian literature. Here, we present a 15-year-old boy who developed psychosis at 9 years of age and during illness developed tic disorder. [ABSTRACT FROM AUTHOR]

Self-organizing computational models with specific intracortical connections can explain many features of visual cortex. However, due to their computation and memory requirements, it is difficult to use such detailed models to study large-scale object segmentation and recognition. This paper describes GLISSOM, a method for scaling a small RF-LISSOM model network into a larger one during self-organization, dramatically reducing time and memory needs while obtaining equivalent results. With GLISSOM it should be possible to simulate all of human V1 at the single-column level using existing supercomputers. The scaling equations GLISSOM uses also allow comparison of biological maps and parameters between individuals and species with different brain region sizes. [Copyright &y& Elsevier]

Kleine-Levin syndrome (KLS) is a rare disorder of sleep diagnosed mainly on clinical grounds. It presents a unique diagnostic dilemma for neurologists and psychiatrists; especially due to a high risk of being diagnosed as a psychiatric condition like a mood disorder. However, there is literature available documenting the cooccurrence of psychiatric illnesses in patients diagnosed with KLS. The following case highlights the above points. [ABSTRACT FROM AUTHOR]