This article presents a systematic mapping, with an analysis of 35 selected works according to established criteria, seeking to connect the points and find relevant information for the following research areas: basic life support, cardiopulmonary resuscitation, serious games, and games for healthcare. Among the main results found, we can mention the representativeness of works by regions and their most productive years, the most common platforms, noting a focus on VR technologies, in addition to identifying the preference for the Unity 3D tool for implementations. It was also possible to show that serious games can be very effective in teaching CPR.