21 results on '"Charles A. Knight"'
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2. From Arlington to Appomattox: Robert E. Lee's Civil War, Day by Day, 1861-1865
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Charles R. Knight and Charles R. Knight
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- 2021
3. Impact of Heading Shift of Barley Cultivars on the Weather Patterns around Heading and Yield in Alaska
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Mingyuan Cheng, Mingchu Zhang, Robert M. Van Veldhuizen, and Charles W. Knight
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heading ,barley cultivars ,yield loss ,temperature and precipitation ,Meteorology. Climatology ,QC851-999 - Abstract
Barley heading date has advanced in Fairbanks (64.83° N, 147.77° W), Alaska, USA. However, it is unclear if this advance coincidently causes weather pattern changes around heading and leads to yield loss. Using the Variety Trial and weather data in Fairbanks and Delta Junction (64.05° N, 145.60° W) from 1991 to 2018, two barley cultivars were selected to analyze the yield and weather trends, the yield variation explained by weather, and the effect of extreme weather on yield. The results showed that the heading date of ‘Otal’ significantly advanced and yield significantly declined in Fairbanks while there were no heading and yield changes of ‘Otal’ in Delta Junction and of ‘Thual’ in both Fairbanks and Delta Junction. The weather pattern changed around heading due to advanced heading of ‘Otal’ in Fairbanks. The climate factors at 7–10 days around heading explained over 50% of ‘Otal’ yield variation in Fairbanks. The results suggest that ‘Otal’ can still be good to plant in Delta Junction but not in Fairbanks. To cope with the climate change in Alaska, the farmers should increase the diversity of barley cultivars, select non-photoperiod sensitive cultivars and cultivars with longer duration from planting to heading, and sow late to avoid the impact on heading and yield.
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- 2022
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4. Secular and Cyclical Movement in the Production and Price of Copper
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Charles Louis Knight and Charles Louis Knight
- Published
- 2017
5. Outcome of 1051 Octogenarian Patients With ST‐Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention: Observational Cohort From the London Heart Attack Group
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Daniel I. Bromage, Daniel A. Jones, Krishnaraj S. Rathod, Claire Grout, M. Bilal Iqbal, Pitt Lim, Ajay Jain, Sundeep S. Kalra, Tom Crake, Zoe Astroulakis, Mick Ozkor, Roby D. Rakhit, Charles J. Knight, Miles C. Dalby, Iqbal S. Malik, Anthony Mathur, Simon Redwood, Philip A. MacCarthy, and Andrew Wragg
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acute myocardial infarction ,aging ,cardiovascular disease ,complications ,elderly ,epidemiology ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BackgroundST‐segment elevation myocardial infarction is increasingly common in octogenarians, and optimal management in this cohort is uncertain. This study aimed to describe the outcomes of octogenarians with ST‐segment elevation myocardial infarction treated by primary percutaneous coronary intervention. Methods and ResultsWe analyzed 10 249 consecutive patients with ST‐segment elevation myocardial infarction treated with primary percutaneous coronary intervention between 2005 and 2011 at 8 tertiary cardiac centers across London, United Kingdom. The primary end point was all‐cause mortality at a median follow‐up of 3 years. In total, 1051 patients (10.3%) were octogenarians, with an average age of 84.2 years, and the proportion increased over the study period (P=0.04). In‐hospital mortality (7.7% vs 2.4%, P
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- 2016
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6. Valley Thunder: The Battle of New Market and the Opening of the Shenandoah Valley Campaign May, 1864
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Charles R. Knight and Charles R. Knight
- Published
- 2010
7. Drug-eluting stents appear superior to bare metal stents for vein-graft PCI in vessels up to a stent diameter of 4 mm
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Oliver P. Guttmann, Daniel A. Jones, Kassem A. Safwan, Sean Gallagher, Krishnaraj S. Rathod, Steve Hamshere, Elliot J. Smith, Ajay K. Jain, Anthony Mathur, Andrew Wragg, Charles J. Knight, and Roshan Weerackody
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Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BackgroundResearch trials have shown improved short-term outcome with drug-eluting stents (DES) over bare metal stents (BMS) in saphenous vein graft (SVG) percutaneous coronary intervention (PCI), primarily by reducing target vessel revascularization (TVR) for in-stent restenosis. We compared the outcomes in patients undergoing SVG stent implantation treated with DES or BMS. In exploratory analyses we investigated the influence of stent generation and diameter.MethodsData were obtained from a prospective database of 657 patients who underwent PCI for SVG lesions between 2003 and 2011. A total of 344 patients had PCI with BMS and 313 with DES. Propensity scores were developed based on 15 observed baseline covariates in a logistic regression model with stent type as the dependent variable. The nearest-neighbour-matching algorithm with Greedy 5-1 Digit Matching was used to produce two patient cohorts of 313 patients each. We assessed major adverse cardiac events (MACE) out to a median of 3.3 years (interquartile range: 2.1-4.1). MACE was defined as all-cause mortality, myocardial infarction (MI), TVR and stroke.ResultsThere was a significant difference in MACE between the two groups in favour of DES (17.9% DES vs. 31.2% BMS group; p = 0.0017) over the 5-year follow-up period. MACE was driven by increased TVR in the BMS group. There was no difference in death, MI or stroke. Adjusted Cox analysis confirmed a decreased risk of MACE for DES compared with BMS 0.75 (95% confidence interval (CI) 0.52-0.94), with no difference in the hazard of all-cause mortality (hazard ratio: 1.08; 95% CI: 0.77-1.68). However, when looking at stent diameters greater than 4 mm, no difference was seen in MACE rates between BMS and DES.ConclusionsOverall in our cohort of patients who had PCI for SVG disease, DES use resulted in lower MACE rates compared with BMS over a 5-year follow-up period; however, for stent diameters over 4 mm no difference in MACE rates was seen.
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- 2016
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8. Climate change and the future of California's endemic flora.
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Scott R Loarie, Benjamin E Carter, Katharine Hayhoe, Sean McMahon, Richard Moe, Charles A Knight, and David D Ackerly
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Medicine ,Science - Abstract
The flora of California, a global biodiversity hotspot, includes 2387 endemic plant taxa. With anticipated climate change, we project that up to 66% will experience >80% reductions in range size within a century. These results are comparable with other studies of fewer species or just samples of a region's endemics. Projected reductions depend on the magnitude of future emissions and on the ability of species to disperse from their current locations. California's varied terrain could cause species to move in very different directions, breaking up present-day floras. However, our projections also identify regions where species undergoing severe range reductions may persist. Protecting these potential future refugia and facilitating species dispersal will be essential to maintain biodiversity in the face of climate change.
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- 2008
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9. Angiography alone versus angiography plus optical coherence tomography to guide percutaneous coronary intervention: outcomes from the pan-London PCI cohort
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Daniel A, Jones, Krishnaraj S, Rathod, Sudheer, Koganti, Stephen, Hamshere, Zoe, Astroulakis, Pitt, Lim, Alexander, Sirker, Constantinos, O'Mahony, Ajay K, Jain, Charles J, Knight, Miles C, Dalby, Iqbal S, Malik, Anthony, Mathur, Roby, Rakhit, Tim, Lockie, Simon, Redwood, Philip A, MacCarthy, Ranil, Desilva, Roshan, Weerackody, Andrew, Wragg, Elliot J, Smith, and Christos V, Bourantas
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Male ,Time Factors ,optical coherence tomography ,percutaneous coronary intervention ,Coronary Artery Disease ,Middle Aged ,Coronary Angiography ,1102 Cardiovascular Medicine And Haematology ,intravascular ultrasound ,Treatment Outcome ,Cardiovascular System & Hematology ,Predictive Value of Tests ,Risk Factors ,London ,Humans ,Female ,Prospective Studies ,Registries ,cardiovascular diseases ,Tomography, Optical Coherence ,Ultrasonography, Interventional ,Aged - Abstract
OBJECTIVES: This study aimed to determine the effect on long-term survival of using optical coherence tomography (OCT) during percutaneous coronary intervention (PCI). BACKGROUND: Angiographic guidance for PCI has substantial limitations. The superior spatial resolution of OCT could translate into meaningful clinical benefits, although limited data exist to date about their effect on clinical endpoints. METHODS: This was a cohort study based on the Pan-London (United Kingdom) PCI registry, which includes 123,764 patients who underwent PCI in National Health Service hospitals in London between 2005 and 2015. Patients undergoing primary PCI or pressure wire use were excluded leaving 87,166 patients in the study. The primary endpoint was all-cause mortality at a median of 4.8 years. RESULTS: OCT was used in 1,149 (1.3%) patients, intravascular ultrasound (IVUS) was used in 10,971 (12.6%) patients, and angiography alone in the remaining 75,046 patients. Overall OCT rates increased over time (p < 0.0001), with variation in rates between centers (p = 0.002). The mean stent length was shortest in the angiography-guided group, longer in the IVUS-guided group, and longest in the OCT-guided group. OCT-guided procedures were associated with greater procedural success rates and reduced in-hospital MACE rates. A significant difference in mortality was observed between patients who underwent OCT-guided PCI (7.7%) compared with patients who underwent either IVUS-guided (12.2%) or angiography-guided (15.7%; p < 0.0001) PCI, with differences seen for both elective (p < 0.0001) and acute coronary syndrome subgroups (p = 0.0024). Overall this difference persisted after multivariate Cox analysis (hazard ratio [HR]: 0.48; 95% confidence interval [CI]: 0.26 to 0.81; p = 0.001) and propensity matching (hazard ratio: 0.39; 95% CI: 0.21 to 0.77; p = 0.0008; OCT vs. angiography-alone cohort), with no difference in matched OCT and IVUS cohorts (HR: 0.88; 95% CI: 0.61 to 1.38; p = 0.43). CONCLUSIONS: In this large observational study, OCT-guided PCI was associated with improved procedural outcomes, in-hospital events, and long-term survival compared with standard angiography-guided PCI.
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- 2018
10. On the Relationship between Pollen Size and Genome Size
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Charles A. Knight, Leighton Dann, Lars Götzenberger, Rachel B. Clancy, Jeremy M. Beaulieu, and Apollo - University of Cambridge Repository
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Article Subject ,3103 Ecology ,Human Genome ,food and beverages ,Regression analysis ,Plant Science ,Biology ,medicine.disease_cause ,Genome ,Regression ,lcsh:QK1-989 ,Positive contrast ,Sister group ,Evolutionary biology ,lcsh:Botany ,Pollen ,FOS: Biological sciences ,Botany ,medicine ,otorhinolaryngologic diseases ,Genetics ,Proxy (statistics) ,Genome size ,31 Biological Sciences - Abstract
Here we test whether genome size is a predictor of pollen size. If it were, inferences of ancient genome size would be possible using the abundant paleo-palynolgical record. We performed regression analyses across 464 species of pollen width and genome size. We found a significant positive trend. However, regression analysis using phylogentically independent contrasts did not support the correlated evolution of these traits. Instead, a large split between angiosperms and gymnosperms for both pollen width and genome size was revealed. Sister taxa were not more likely to show a positive contrast when compared to deeper nodes. However, significantly more congeneric species had a positive trend than expected by chance. These results may reflect the strong selection pressure for pollen to be small. Also, because pollen grains are not metabolically active when measured, their biology is different than other cells which have been shown to be strongly related to genome size, such as guard cells. Our findings contrast with previously published research. It was our hope that pollen size could be used as a proxy for inferring the genome size of ancient species. However, our results suggest pollen is not a good candidate for such endeavors.
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- 2017
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11. Genome Size Scaling through Phenotype Space
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Jeremy M. Beaulieu and Charles A. Knight
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Phylogenetic tree ,DNA, Plant ,Plant Science ,Phenotypic trait ,Articles ,Biology ,biology.organism_classification ,Genome ,Phenotype ,Order (biology) ,Gymnosperm ,Phylogenetics ,Evolutionary biology ,Botany ,Seeds ,Photosynthesis ,Genome size ,Genome, Plant ,Phylogeny - Abstract
† Background and Aims Early observations that genome size was positively correlated with cell size formed the basis of hypothesized consequences of genome size variation at higher phenotypic scales. This scaling was supported by several studies showing a positive relationship between genome size and seed mass, and various metrics of growth and leaf morphology. However, many of these studies were undertaken with limited species sets, and often performed within a single genus. Here we seek to generalize the relationship between genome size and the phenotype by examining eight phenotypic traits using large cross-species comparisons involving diverse assemblages of angiosperm and gymnosperm species. These analyses are presented in order of increasing scale (roughly equating to the number of cells required to produce a particular phenotypic trait), following the order of: cell size (guard cell and epidermal), stomatal density, seed mass, leaf mass per unit area (LMA), wood density, photosynthetic rate and finally maximum plant height. † Scope The results show that genome size is a strong predictor of phenotypic traits at the cellular level (guard cell length and epidermal cell area had significant positive relationships with genome size). Stomatal density decreased with increasing genome size, but this did not lead to decreased photosynthetic rate. At higher phenotypic scales, the predictive power of genome size generally diminishes (genome size had weak predictive power for both LMA and seed mass), except in the interesting case of maximum plant height (tree species tend to have small genomes). There was no relationship with wood density. The general observation that species with larger genome size have larger seed mass was supported; however, species with small genome size can also have large seed masses. All of these analyses involved robust comparative methods that incorporate the phylogenetic relationships of species. † Conclusions Genome size correlations are quite strong at the cellular level but decrease in predictive power with increasing phenotypic scale. Our hope is that these results may lead to new mechanistic hypotheses about why genome size scaling exists at the cellular level, and why nucleotypic consequences diminish at higher phenotypic scales.
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- 2008
12. In the Driver's Seat: Rico and Education
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Colleen K. Henry, Diana L. Ortiz-Montalvo, Louise Nuijens, Jason H. Lowenstein, Shaunna L. Donaher, Jennifer D. Small, Ela Grzeszczak, Subhashree Mishra, Erin Riepe, Haiwei Shen, Dennis O'Donnell, Ieng Jo, Charles A. Knight, Jørgen Jensen, Sarah Scalia, Simona Bordoni, Olga L. Mayol-Bracero, Paquita Zuidema, Michael Siedsma, Bjorn Stevens, Efthymios Serpetzoglou, Maylissa Deliz, Humberto Caro-Gautier, Jonathan Zawislak, Anne Marie Hertel, Eric Snodgrass, Jennifer L. Davison, Virendra P. Ghate, Brian Medeiros, Judith Malley, Robert M. Rauber, Marilé Colón-Robles, Yarilis Méndez-Lopez, Sarah D. Bereznicki, David C. Rogers, Sabine Göke, Flavia Morales-García, Michael C. Kruk, Kristen L. Rasmussen, Panu Trivej, and Harry T. Ochs
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Atmospheric Science ,Engineering ,010504 meteorology & atmospheric sciences ,Meteorology ,business.industry ,4. Education ,Field (Bourdieu) ,05 social sciences ,050301 education ,01 natural sciences ,GeneralLiterature_MISCELLANEOUS ,Aeronautics ,ComputingMilieux_COMPUTERSANDEDUCATION ,business ,0503 education ,Field campaign ,0105 earth and related environmental sciences - Abstract
The Rain in Cumulus over the Ocean (RICO) field campaign carried out a wide array of educational activities, including a major first in a field project—a complete mission, including research flights, planned and executed entirely by students. This article describes the educational opportunities provided to the 24 graduate and 9 undergraduate students who participated in RICO.
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- 2007
13. Rain in shallow cumulus over the ocean: the RICO Campaign
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Louise Nuijens, Robert A. Rilling, S. Tucker, Steven K. Krueger, W. A. Brewer, James R. Anderson, E. Burnet, Daniel O'Sullivan, Bruce A. Albrecht, Bart Geerts, Brian G. Heikes, H. Gerber, Jeffrey L. Stith, Patrick Y. Chuang, Jørgen Jensen, Olga L. Mayol-Bracero, Sabine Göke, R. P. Lawson, Sonia Lasher-Trapp, Cynthia H. Twohy, James G. Hudson, Eric Snodgrass, L. Gomes, Gabor Vali, Paquita Zuidema, Pavlos Kollias, Bruce Baker, P. R. A. Brown, Harry T. Ochs, Bjorn Stevens, Jean-Louis Brenguier, Alan R. Bandy, D. C. Rogers, William R. Cotton, Donald C. Thornton, Charles A. Knight, Larry Di Girolamo, A. P. Siebesma, Christopher W. Fairall, Donald H. Lenschow, Robert M. Rauber, and Alan M. Blyth
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Atmospheric Science ,Meteorology ,Remote sensing (archaeology) ,law ,Climatology ,Shallow convection ,Sampling (statistics) ,Environmental science ,Weather and climate ,Radar ,Trade wind ,Field campaign ,law.invention - Abstract
Shallow, maritime cumuli are ubiquitous over much of the tropical oceans, and characterizing their properties is important to understanding weather and climate. The Rain in Cumulus over the Ocean (RICO) field campaign, which took place during November 2004–January 2005 in the trades over the western Atlantic, emphasized measurements of processes related to the formation of rain in shallow cumuli, and how rain subsequently modifies the structure and ensemble statistics of trade wind clouds. Eight weeks of nearly continuous S-band polarimetric radar sampling, 57 flights from three heavily instrumented research aircraft, and a suite of ground- and ship-based instrumentation provided data on trade wind clouds with unprecedented resolution. Observational strategies employed during RICO capitalized on the advances in remote sensing and other instrumentation to provide insight into processes that span a range of scales and that lie at the heart of questions relating to the cause and effects of rain from shallow maritime cumuli.
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- 2007
14. The Large Genome Constraint Hypothesis: Evolution, Ecology and Phenotype
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Nicole A. Molinari, Dmitri A. Petrov, and Charles A. Knight
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Phylogenetic tree ,DNA, Plant ,Ecology ,Plant genetics ,Temperature ,Plant Science ,Bacterial genome size ,Biology ,Plants ,Phenotype ,Genome ,Biological Evolution ,Constraint (information theory) ,Evolvability ,Evolutionary biology ,Mechanisms and Evolutionary Patterns of Genome Size Change ,Genome size ,Genome, Plant - Abstract
• Background and Aims If large genomes are truly saturated with unnecessary ‘junk’ DNA, it would seem natural that there would be costs associated with accumulation and replication of this excess DNA. Here we examine the available evidence to support this hypothesis, which we term the ‘large genome constraint’. We examine the large genome constraint at three scales: evolution, ecology, and the plant phenotype. • Scope In evolution, we tested the hypothesis that plant lineages with large genomes are diversifying more slowly. We found that genera with large genomes are less likely to be highly specious – suggesting a large genome constraint on speciation. In ecology, we found that species with large genomes are under-represented in extreme environments – again suggesting a large genome constraint for the distribution and abundance of species. Ultimately, if these ecological and evolutionary constraints are real, the genome size effect must be expressed in the phenotype and confer selective disadvantages. Therefore, in phenotype, we review data on the physiological correlates of genome size, and present new analyses involving maximum photosynthetic rate and specific leaf area. Most notably, we found that species with large genomes have reduced maximum photosynthetic rates – again suggesting a large genome constraint on plant performance. Finally, we discuss whether these phenotypic correlations may help explain why species with large genomes are trimmed from the evolutionary tree and have restricted ecological distributions. • Conclusion Our review tentatively supports the large genome constraint hypothesis.
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- 2005
15. A Political Biography of Richard Steele
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Charles A Knight and Charles A Knight
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- DA501.S74
- Abstract
Richard Steele is famous as an early writer of sentimental drama and as half of the writing team, Addison and Steele. He is notable both for the indirect propaganda he developed with Addison and for the open partisanship of his own periodicals. He wrote extensively about responsible economics but was famously irresponsible in his own affairs.
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- 2009
16. The Literature of Satire
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Charles A. Knight and Charles A. Knight
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- Satire--History and criticism
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The Literature of Satire is an accessible but sophisticated and wide-ranging study of satire from the classics to the present in plays, novels and the press as well as in verse. In it Charles Knight analyses the rhetorical problems created by satire's complex relations to its community, and examines how it exploits the genres it borrows. He argues that satire derives from an awareness of the differences between appearance, ideas and discourse. Knight provides illuminating readings of such satirists familiar and unfamiliar as Horace, Lucian, Jonson, Molière, Swift, Pope, Byron, Flaubert, Ostrovsky, Kundera, and Rushdie. This broad-ranging examination sheds light on the nature and functions of satire as a mode of writing, as well as on theoretical approaches to it. It will be of interest to scholars interested in literary theory as well as those specifically interested in satire.
- Published
- 2004
17. Role of Nonpolar Amino Acid Functional Groups in the Surface Orientation-Dependent Adsorption of Natural and Synthetic Antifreeze Peptides on Ice.
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Andrzej Wierzbicki, Charles A. Knight, E. Alan Salter, Camden N. Henderson, and Jeffry D. Madura
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- *
SURFACE chemistry , *PHYSICAL & theoretical chemistry , *CAPILLARITY , *SURFACES (Physics) - Abstract
The aim of this study is to investigate the significance of nonpolar functional groups in the surface orientation-dependent adsorption of natural and synthetic antifreeze proteins (AFPs) on ice. We investigate using nanoliter osmometry, ice etching, and circular dichroism spectroscopy a series of nine designed α-helical peptides to probe the nature of their selectivity between the bipyramidal {201} and the secondary prismatic {21̅0} faces of ice, identified earlier as the preferred faces for adsorption of winter flounder (WF) and shorthorn sculpin type I AFPs, respectively. Complementarities between the AFP’s surface features, comprised chiefly of nonpolar groups, and the well-defined sites on ice surface, allow close contact. Because our experimental studies demonstrate that the function of AFPs relies on participation of both polar and nonpolar residues in the ice surface adsorption, we carry out computational modeling to explore both kinds of contacts at the ice surface. On the basis of results of semiempirical quantum mechanical calculations of the WF AFP/ice system, we propose and discuss a new model for the binding of WF AFP to the {201} surface of ice, in a groove formed between {21̅0} and {011} facets. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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18. The Royal University of Ireland
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Charles Frederick Knight
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business.industry ,Correspondence ,General Engineering ,General Earth and Planetary Sciences ,Medicine ,Library science ,General Medicine ,business ,Data science ,General Environmental Science - Published
- 1883
19. FELLOWSHIP OF THE ROYAL COLLEGE OF SURGEONS, EDINBURGH
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Charles Frederick Knight
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business.industry ,Correspondence ,General Engineering ,General Earth and Planetary Sciences ,Library science ,Medicine ,General Medicine ,business ,Data science ,General Environmental Science - Published
- 1903
20. A rapid protocol for the prevention of contrast-induced renal dysfunction (RAPPID study)
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Christopher S. Baker, Andrew Wragg, Sanjay Kumar, Rodney De Silva, Roger J. Hall, Lawrence R. Baker, and Charles J. Knight
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Cardiology and Cardiovascular Medicine - Full Text
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21. Genome Size Evolution in Relation to Leaf Strategy and Metabolic Rates Revisited.
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Jeremy M. Beaulieu, Ilia J. Leitch, and Charles A. Knight
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GENOMES ,GENETICS ,GENE libraries ,MICROBIAL genomes - Abstract
Background and Aims It has been proposed that having too much DNA may carry physiological consequences for plants. The strong correlation between DNA content, cell size and cell division rate could lead to predictable morphological variation in plants, including a negative relationship with leaf mass per unit area (LMA). In addition, the possible increased demand for resources in species with high DNA content may have downstream effects on maximal metabolic efficiency, including decreased metabolic rates. Methods Tests were made for genome size-dependent variation in LMA and metabolic rates (mass-based photosynthetic rate and dark respiration rate) using our own measurements and data from a plant functional trait database (Glopnet). These associations were tested using two metrics of genome size: bulk DNA amount (2C DNA) and monoploid genome size (1Cx DNA). The data were analysed using an evolutionary framework that included a regression analysis and independent contrasts using a phylogenetic tree with estimates of molecular diversification times. A contribution index for the LMA data set was also calculated to determine which divergences have the greatest influence on the relationship between genome size and LMA. Key Results and Conclusions A significant negative association was found between bulk DNA amount and LMA in angiosperms. This was primarily a result of influential divergences that may represent early shifts in growth form. However, divergences in bulk DNA amount were positively associated with divergences in LMA, suggesting that the relationship may be indirect and mediated through other traits directly related to genome size. There was a significant negative association between genome size and metabolic rates that was driven by a basal divergence between angiosperms and gymnosperms; no significant independent contrast results were found. Therefore, it is concluded that genome size-dependent constraints acting on metabolic efficiency may not exist within seed plants. [ABSTRACT FROM AUTHOR]
- Published
- 2007
- Full Text
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