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3,064 results on '"Angelini, P."'

1. Virtual Simulation in Teacher Education across Borders

Author

María Laura Angelini, Rut Muñiz, and Alexis Cloquell Lozano

Abstract

There is already an abundant literature on the virtues of simulation in education. However, there is also a lack of assessment instruments to determine the impact of virtual simulation and virtual exchange on participants' self-realisation of learning in teacher education. The aim of this study is to identify the variables that best describe students' learning of current educational issues. A questionnaire consisting of Likert-type items was used as a metacognitive assessment tool to provide data for the study. An exploratory longitudinal study was conducted over three years. Data were collected using students' answers to the questionnaire. A convenience sampling procedure was used, with participating students enrolled in the Didactic Resources module of English as a Second Language (ESL) in an Official Master's Degree in Teacher Training in Compulsory Secondary Education and Baccalaureate, Vocational Training, and Language Teaching. The most strongly correlated variables that best explain the dependent variable ("I have gained deeper insights into current educational issues") addressed inclusion, special learning needs, service learning, and simulation through intercultural dialogue. Each of the variables significantly contributes to the estimation of perceived acquisition of insight into current educational issues through virtual simulation.

Published
2024
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9. Associations of maternal lifestyle factors with inadequate pregnancy weight gain: findings from the baseline data of the LIMIT prospective cohort study

Author

El Masri, Dana, Alemayohu, Mulubirhan Assefa, Loperfido, Federica, Bianco, Irene, Ferrara, Chiara, Cerbo, Rosa Maria, Ghirardello, Stefano, Monti, Maria Cristina, Maccarini, Beatrice, Sottotetti, Francesca, Civardi, Elisa, Garofoli, Francesca, Angelini, Micol, Cena, Hellas, and De Giuseppe, Rachele

Published
2024
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13. Efficacy and safety of the serratus anterior plane block (SAP block) for pain management in patients with multiple rib fractures in the emergency department: a retrospective study

Author

Serra, Sossio, Santonastaso, Domenico Pietro, Romano, Giuseppe, Riccardi, Alessandro, Nigra, Stefano Geniere, Russo, Emanuele, Angelini, Mario, Agnoletti, Vanni, Guarino, Mario, Cimmino, Claudia Sara, Spampinato, Michele Domenico, Francesconi, Raffella, and Iaco, Fabio De

Published
2024
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14. Chorio-retinal vessel density in women affected by functional hypothalamic amenorrhea: a monocentric observational cross-sectional study to evaluate the impact of hypoestrogenism on chorio-retinal vascularization

Author

Diterlizzi, Alice, Tropea, Anna, Angelini, Emanuela, Cestrone, Valentina, Fasciani, Romina, Merola, Annamaria, Notaristefano, Giovanna, Policriti, Martina Asia, Polimeno, Teresa, Ranalli, Monia, Savastano, Maria Cristina, Tannous, Ghazal, Versace, Valeria, Rizzo, Stanislao, Scambia, Giovanni, Lanzone, Antonio, and Apa, Rosanna

Published
2024
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23. Clinical, developmental and serotonemia phenotyping of a sample of 70 Italian patients with Phelan-McDermid Syndrome

Author

Lisa Asta, Arianna Ricciardello, Francesca Cucinotta, Laura Turriziani, Maria Boncoddo, Fabiana Bellomo, Jessica Angelini, Martina Gnazzo, Giulia Scandolo, Giulia Pisanò, Francesco Pelagatti, Fethia Chehbani, Michela Camia, and Antonio M. Persico

Subjects
22q13 deletion syndrome, Autism spectrum disorder, Hyperserotonemia, Intellectual disability, Macrocephaly, Neuroinflammation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Abstract Background Phelan-McDermid syndrome (PMS) is caused by monoallelic loss or inactivation at the SHANK3 gene, located in human chr 22q13.33, and is often associated with Autism Spectrum Disorder (ASD). Objectives To assess the clinical and developmental phenotype in a novel sample of PMS patients, including for the first time auxometric trajectories and serotonin blood levels. Methods 70 Italian PMS patients were clinically characterized by parental report, direct medical observation, and a thorough medical and psychodiagnostic protocol. Serotonin levels were measured in platelet-rich plasma by HPLC. Results Our sample includes 59 (84.3%) cases with chr. 22q13 terminal deletion, 5 (7.1%) disruptive SHANK3 mutations, and 6 (8.6%) ring chromosome 22. Intellectual disability was present in 69 (98.6%) cases, motor coordination disorder in 65 (92.9%), ASD in 20 (28.6%), and lifetime bipolar disorder in 12 (17.1%). Prenatal and postnatal complications were frequent (22.9%-48.6%). Expressive and receptive language were absent in 49 (70.0%) and 19 (27.1%) cases, respectively. Decreased pain sensitivity was reported in 56 (80.0%), hyperactivity in 49 (80.3%), abnormal sleep in 45 (64.3%), congenital dysmorphisms in 35 (58.3%), chronic stool abnormalities and especially constipation in 29 (41.4%). Parents reported noticing behavioral abnormalities during early childhood immediately after an infective episode in 34 (48.6%) patients. Brain MRI anomalies were observed in 53 (79.1%), EEG abnormalities in 16 (23.5%), kidney and upper urinary tract malformations in 18 (28.1%). Two novel phenotypes emerged: (a) a subgroup of 12/44 (27.3%) PMS patients displays smaller head size at enrollment (mean age 11.8 yrs) compared to their first year of neonatal life, documenting a deceleration of head growth (p

Published
2024
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24. A preventive care approach for oral health in nursing homes: a qualitative study of healthcare workers’ experiences

Author

Lisa Bellander, Eva Angelini, Pia Andersson, Catharina Hägglin, and Helle Wijk

Subjects
Geriatrics, RC952-954.6
Abstract

Abstract Background Oral health problems are common among care-dependent older adults living in nursing homes. Developing strategies to prevent the deterioration of oral health is therefore crucial to avoid pain and tooth loss. A standardized work widely used in nursing homes in Sweden is the quality register Senior Alert (SA), which assesses age-related risks concerning e.g. pressure sores, falls, malnutrition and oral health. The oral health assessment is performed with the Revised Oral Assessment Guide-Jönköping (ROAG-J), which also includes planning and implementation of preventive oral care interventions with the goal of achieving good quality care. However, what facilitates and hinders healthcare workers in working with oral health in SA remains unexplored. The aim of this study was to describe healthcare workers’ experiences of assessing oral health with the ROAG-J, planning and performing preventive oral health care actions in accordance with SA in nursing homes. Methods Healthcare workers (n = 28) in nursing homes in two Swedish municipalities participated and data was collected through six focus group interviews. Reflexive thematic analysis was used to identify patterns of meaning in the data. Results Themes generated in the analysis were: (1) A structured process promotes communication and awareness and stresses the importance of oral health; (2) Oral care for frail older adults is challenging and triggers ethical dilemmas; (3) Unclear responsibilities, roles and routines in the organization put oral health at risk; (4) Differences in experience and competence among healthcare staff call for educational efforts. Conclusions The structured way of working increases staff awareness and prioritization of oral health in nursing homes. The main challenges for the healthcare workers were residents’ reluctance to participate in oral care activities and oral care being more complicated since most older adults today are dentate. Organizational challenges lay in creating good routines and clarifying staff roles and responsibilities, which will require continuous staff training and increased management involvement.

Published
2024
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25. Vagal nerve stimulation in myocardial ischemia/reperfusion injury: from bench to bedside

Author

Giuseppe Giannino, Lorenzo Nocera, Maria Andolfatto, Valentina Braia, Federico Giacobbe, Francesco Bruno, Andrea Saglietto, Filippo Angelini, Ovidio De Filippo, Fabrizio D’Ascenzo, Gaetano Maria De Ferrari, and Veronica Dusi

Subjects
Ischemia/reperfusion injury, Transcutaneous vagal nerve stimulation, Vagus nerve, Tragus, Bioelectronic medicine, Autonomic imbalance, Medical technology, R855-855.5
Abstract

Abstract The identification of acute cardioprotective strategies against myocardial ischemia/reperfusion (I/R) injury that can be applied in the catheterization room is currently an unmet clinical need and several interventions evaluated in the past at the pre-clinical level have failed in translation. Autonomic imbalance, sustained by an abnormal afferent signalling, is a key component of I/R injury. Accordingly, there is a strong rationale for neuromodulation strategies, aimed at reducing sympathetic activity and/or increasing vagal tone, in this setting. In this review we focus on cervical vagal nerve stimulation (cVNS) and on transcutaneous auricular vagus nerve stimulation (taVNS); the latest has the potential to overcome several of the issues of invasive cVNS, including the possibility of being used in an acute setting, while retaining its beneficial effects. First, we discuss the pathophysiology of I/R injury, that is mostly a consequence of the overproduction of reactive oxygen species. Second, we describe the functional anatomy of the parasympathetic branch of the autonomic nervous system and the most relevant principles of bioelectronic medicine applied to electrical vagal modulation, with a particular focus on taVNS. Then, we provide a detailed and comprehensive summary of the most relevant pre-clinical studies of invasive and non-invasive VNS that support its strong cardioprotective effect whenever there is an acute or chronic cardiac injury and specifically in the setting of myocardial I/R injury. The potential benefit in the emerging field of post cardiac arrest syndrome (PCAS) is also mentioned. Indeed, electrical cVNS has a strong anti-adrenergic, anti-inflammatory, antioxidants, anti-apoptotic and pro-angiogenic effect; most of the involved molecular pathways were already directly confirmed to take place at the cardiac level for taVNS. Pre-clinical data clearly show that the sooner VNS is applied, the better the outcome, with the possibility of a marked infarct size reduction and almost complete left ventricular reverse remodelling when VNS is applied immediately before and during reperfusion. Finally, we describe in detail the limited but very promising clinical experience of taVNS in I/R injury available so far.

Published
2024
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26. Cancer incidence (2000–2020) among individuals under 35: an emerging sex disparity in oncology

Author

Alessandro Cavazzani, Claudia Angelini, Dario Gregori, and Luca Cardone

Subjects
Pancreatic cancer, Gastrointestinal cancer, Incidence data, Young population, Age-sex differences, Risk populations, Medicine
Abstract

Abstract Background Aggressive malignancies, such as pancreatic cancer, are increasingly impacting young, female populations. Our investigation centered on whether the observed trends in cancer incidence were unique to pancreatic cancer or indicative of a broader trend across various cancer types. To delve deeper into this phenomenon, we analyzed cancer incidence trends across different age and sex groups. Furthermore, we explored differences in cancer incidence within specific young subgroups aged 18 to 26 and 27 to 34, to better understand the emerging incidence trend among young individuals. Methods This study collected cancer incidence data from one of the Surveillance, Epidemiology, and End Results cancer registry databases (SEER22), with 10,183,928 total cases from 2000 to 2020. Data were analyzed through Joinpoint trend analysis approach to evaluate sex- and age-specific trends in cancer incidence. Exposure rates were reported as Average Annual Percentage Changes (AAPCs). Results The analysis revealed significant age and sex-specific disparities, particularly among individuals aged 18–26 and 27–34. Pancreatic cancer incidence rates increased more in females aged 18–26 (AAPC, 9.37% [95% CI, 7.36–11.41%]; p

Published
2024
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30. Clarifying the radiative decay of the Hoyle state with charged-particle spectroscopy

Author

Dell’Aquila, D., Lombardo, I., Redigolo, L., Vigilante, M., Angelini, F., Baldesi, L., Barlini, S., Best, A., Camaiani, A., Casini, G., Ciampi, C., Cicerchia, M., D’Andrea, M., Diklić, J., Fabris, D., Gongora Servin, B., Gottardo, A., Gramegna, F., Imbriani, G., Marchi, T., Massara, A., Mengoni, D., Ordine, A., Palada, L., Pasquali, G., Piantelli, S., Pilotto, E., Rapagnani, D., Sigmund, M., Stefanini, A., Stramaccioni, D., Tagnani, D., Tišma, I., Valdré, S., Verde, G., and Vukman, N.

Published
2024
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34. VectAbundance: a spatio-temporal database of Aedes mosquitoes observations

Author

Da Re, Daniele, Marini, Giovanni, Bonannella, Carmelo, Laurini, Fabrizio, Manica, Mattia, Anicic, Nikoleta, Albieri, Alessandro, Angelini, Paola, Arnoldi, Daniele, Blaha, Marharyta, Bertola, Federica, Caputo, Beniamino, De Liberato, Claudio, della Torre, Alessandra, Flacio, Eleonora, Franceschini, Alessandra, Gradoni, Francesco, Kadriaj, Përparim, Lencioni, Valeria, Del Lesto, Irene, La Russa, Francesco, Lia, Riccardo Paolo, Montarsi, Fabrizio, Otranto, Domenico, L’Ambert, Gregory, Rizzoli, Annapaola, Rombolà, Pasquale, Romiti, Federico, Stancher, Gionata, Torina, Alessandra, Velo, Enkelejda, Virgillito, Chiara, Zandonai, Fabiana, and Rosà, Roberto

Published
2024
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47. Physical activity practiced at a young age is associated with a less severe subsequent clinical presentation in facioscapulohumeral muscular dystrophy

Author

Bettio, Cinzia, Banchelli, Federico, Salsi, Valentina, Vicini, Roberto, Crisafulli, Oscar, Ruggiero, Lucia, Ricci, Giulia, Bucci, Elisabetta, Angelini, Corrado, Berardinelli, Angela, Bonanno, Silvia, D’Angelo, Maria Grazia, Di Muzio, Antonio, Filosto, Massimiliano, Frezza, Erica, Maggi, Lorenzo, Mongini, Tiziana, Pegoraro, Elena, Rodolico, Carmelo, Scarlato, Marina, Vattemi, Gaetano, Velardo, Daniele, Tomelleri, Giuliano, D’Amico, Roberto, D’Antona, Giuseppe, and Tupler, Rossella

Published
2024
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