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Cancer incidence (2000–2020) among individuals under 35: an emerging sex disparity in oncology

Authors :
Alessandro Cavazzani
Claudia Angelini
Dario Gregori
Luca Cardone
Source :
BMC Medicine, Vol 22, Iss 1, Pp 1-10 (2024)
Publication Year :
2024
Publisher :
BMC, 2024.

Abstract

Abstract Background Aggressive malignancies, such as pancreatic cancer, are increasingly impacting young, female populations. Our investigation centered on whether the observed trends in cancer incidence were unique to pancreatic cancer or indicative of a broader trend across various cancer types. To delve deeper into this phenomenon, we analyzed cancer incidence trends across different age and sex groups. Furthermore, we explored differences in cancer incidence within specific young subgroups aged 18 to 26 and 27 to 34, to better understand the emerging incidence trend among young individuals. Methods This study collected cancer incidence data from one of the Surveillance, Epidemiology, and End Results cancer registry databases (SEER22), with 10,183,928 total cases from 2000 to 2020. Data were analyzed through Joinpoint trend analysis approach to evaluate sex- and age-specific trends in cancer incidence. Exposure rates were reported as Average Annual Percentage Changes (AAPCs). Results The analysis revealed significant age and sex-specific disparities, particularly among individuals aged 18–26 and 27–34. Pancreatic cancer incidence rates increased more in females aged 18–26 (AAPC, 9.37% [95% CI, 7.36–11.41%]; p

Details

Language :
English
ISSN :
17417015
Volume :
22
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.7d6db8c50acd4563954f744e8828af3f
Document Type :
article
Full Text :
https://doi.org/10.1186/s12916-024-03574-x