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International audience; Infants come to learn several hundreds of word forms by two years of age, and it is possible this involves carving these forms out from continuous speech. It has been proposed that the task is facilitated by the presence of prosodic boundaries. We revisit this claim by running computational models of word segmentation, with and without prosodic information, on a corpus of infant-directed speech. We use five cognitively-based algorithms, which vary in whether they employ a sub-lexical or a lexical segmentation strategy and whether they are simple heuristics or embody an ideal learner. Results show that providing expert-annotated prosodic breaks does not uniformly help all segmentation models. The sub-lexical algorithms, which perform more poorly, benefit most, while the lexical ones show a very small gain. Moreover, when prosodic information is derived automatically from the acoustic cues infants are known to be sensitive to, errors in the detection of the boundaries lead to smaller positive effects, and even negative ones for some algorithms. This shows that even though infants could potentially use prosodic breaks, it does not necessarily follow that they should incorporate prosody into their segmentation strategies, when confronted with realistic signals.

[EN]Background: The urban environment may influence neurodevelopment from conception onwards, but there is no evaluation of the impact of multiple groups of exposures simultaneously. We investigated the association between early-life urban environment and cognitive and motor function in children. Methods: We used data from 5403 mother-child pairs from four population-based birth-cohorts (UK, France, Spain, and Greece). We estimated thirteen urban home exposures during pregnancy and childhood, including: built environment, natural spaces, and air pollution. Verbal, non-verbal, gross motor, and fine motor functions were assessed using validated tests at five years old. We ran adjusted multi-exposure models using the Deletion-Substitution-Addition algorithm. Results: Higher greenness exposure within 300 m during pregnancy was associated with higher verbal abilities (1.5 points (95% confidence interval 0.4, 2.7) per 0.20 unit increase in greenness). Higher connectivity density within 100 m and land use diversity during pregnancy were related to lower verbal abilities. Childhood exposure to PM2.5 mediated 74% of the association between greenness during childhood and verbal abilities. Higher exposure to PM2.5 during pregnancy was related to lower fine motor function (-1.2 points (-2.1, -0.4) per 3.2 mu g/m3 increase in PM2.5). No associations were found with non-verbal abilities and gross motor function. Discussion: This study suggests that built environment, greenness, and air pollution may impact child cognitive and motor function at five years old. This study adds evidence that well-designed urban planning may benefit children's cognitive and motor development. Acknowledgements We are grateful to all the participating children, parents, practi-tioners and researchers in the four countries who took part in this study. This work was supported by funding from the European Community's Seventh Framework Programme [FP7/2007-206 n 308333; the HELIX project] . This INMA cohort was funded by grants from Instituto de Salud Carlos III (Red INMA G03/176; CB06/02/0041; PI041436; PI081151 incl. FEDER funds, FIS PI06/0867, FIS-PI09/00090, FIS and FIS-PI18/01142 incl. FEDER funds, FIS-FEDER: PI03/1615, PI04/1509, PI04/1112, PI04/1931, PI05/1079, PI05/1052, PI06/1213, PI07/0314, PI09/02647, PI11/01007, PI11/02591, PI11/02038, PI13/1944, PI13/2032, PI14/00891, PI14/01687, PI16/1288, PI16/00118 and PI17/00663; FIS-FSE: 17/00260; Miguel Servet-FEDER CP11/00178, CP15/00025, CPII16/00051, and CPII18/00018) , from UE (FP7-ENV-2011 cod 282957, HEALTH.2010.2.4.5-1, and H2020 n 824989) , Generalitat de Catalunya-CIRIT 1999SGR 00241, Fundacio La marato de TV3 (090430) , Generalitat Valenciana: FISABIO (UGP 15-230, UGP-15-244, and UGP-15-249) , Alicia Koplowitz Foundation 2017, CIBERESP, Department of Health of the Basque Government (2013111089, 2009111069, 2013111089, 2015111065 and 2018111086) , Provincial Government of Gipuzkoa (DFG06/002, DFG08/001, DFG15/221 and DFG 89/17) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu , Legazpi, Azkoitia y Azpeitia y Beasain) . We acknowledge support from the Spanish Ministry of Science and Inno-vation and the State Research Agency through the "Centro de Excelencia Severo Ochoa 2019-2023" Program (CEX2018-000806-S) , and support from the Generalitat de Catalunya through the CERCA Program. The work was also supported by MICINN [MTM2015-68140-R] and Centro Nacional de Genotipado-CEGEN-PRB2-ISCIII (Spain) . The Rhea project was financially supported by European projects, and the Greek Ministry of Health (Program of Prevention of obesity and neurodevelopmental disorders in preschool children, in Heraklion district, Crete, Greece: 2011-2014; "Rhea Plus": Primary Prevention Program of Environmental Risk Factors for Reproductive Health, and Child Health: 2012-15) . This paper presents independent research funded by the National Institute for Health Research (NIHR) under its Collaboration for Applied Health Research and Care (CLAHRC) for Yorkshire and Humber (UK) . The EDEN study was supported by Foundation for medical research (FRM) , National Agency for Research (ANR) , National Institute for Research inPublic health (IRESP: TGIR cohorte sante 2008 program) , French Min-istry of Health (DGS) , French Ministry of Research, INSERM Bone and Joint Diseases National Research (PRO-A) , and Human Nutrition Na-tional Research Programs, Paris-Sud University, Nestle, French National Institute for Population Health Surveillance (InVS) , French National Institute for Health Education (INPES) , the European Union FP7 pro-grams (ESCAPE, ENRIECO, Medall projects) , Diabetes National Research Program (through a collaboration with the French Association of Diabetic Patients (AFD) ) , French Agency for Environmental Health Safety and French National Agency for Food Security (now ANSES) , Mutuelle Generale de l'Education Nationale a complementary health insurance (MGEN) , French-speaking association for the study of diabetes and metabolism (ALFEDIAM) . Core support for Born in Bradford is also provided by the Wellcome Trust (WT101597MA, UK) . Born in Bradford (BiB) is only possible because of the enthusiasm and commitment of the children and parents in BiB. We are grateful to all the participants, health professionals, schools and researchers who have made BiB happen. BiB receives funding from the ESRC/MRC, the Wellcome Trust (WT101597MA) and the National Institute for Health Research York-shire and Humber ARC (reference: NIHR20016) . M. Mon-Williams was supported by a Fellowship from the Alan Turing Institute. Additional funding from the National Institute of Environmental Health Science supported Dr Chatzi (R01ES030691, R01ES029944, R01ES030364, R21ES029681, and P30ES007048) . The views expressed are those of the authors, and not necessarily those of the NHS or the NIHR. None of the funders were involved in designing the study, collecting the data, analyzing or interpreting the data, deciding to submit the article for publication, or the writing of the report. Data sharing statement The HELIX data warehouse has been established as an accessible resource for collaborative research involving researchers external to the project. Access to HELIX data is based on approval by the HELIX Project Executive Committee and by the individual cohorts. Further details on the content of the data warehouse (data catalogue) and procedures for external access are described on the project website (http:// www.proj-ecthelix.eu/index.php/es/data-inventory) .

Animal communication has long been thought to be subject to pressures and constraints associated with social relationships. However, our understanding of how the nature and quality of social relationships relates to the use and evolution of communication is limited by a lack of directly comparable methods across multiple levels of analysis. Here, we analysed observational data from 111 wild groups belonging to 26 non-human primate species, to test how vocal communication relates to dominance style (the strictness with which a dominance hierarchy is enforced, ranging from 'despotic' to 'tolerant'). At the individual-level, we found that dominant individuals who were more tolerant vocalized at a higher rate than their despotic counterparts. This indicates that tolerance within a relationship may place pressure on the dominant partner to communicate more during social interactions. At the species-level, however, despotic species exhibited a larger repertoire of hierarchy-related vocalizations than their tolerant counterparts. Findings suggest primate signals are used and evolve in tandem with the nature of interactions that characterize individuals' social relationships. Publisher PDF

This paper presents a comparative analysis of the survey results on communication competencies in mentoring in Lithuania and Latvia. In mentoring, it is imperative to examine barriers to communication competencies between business consultants (from now on referred to as "mentors") and start-up entrepreneurs or those intending to start a business (from now on referred to as "mentees") and propose solutions on how to enhance and maintain the business mentor network by utilizing communication technologies.

This paper explains the current practices of the child welfare system in the context of Lithuania. In Europe, research on child welfare has a long history; however, the child welfare situation in Lithuania has not been systematically studied, nor has it been provided with the research-based knowledge necessary for the development of the system. Based on qualitative research results, the paper sheds light on how the voice of the child is heard in Lithuanian child and family social work practice. The research participants in the present study were children and family social workers. The research results indicate that adult-centered family social work practices are dominant and the voice of the child is misleading in the intervention process.

At present, we increasingly encounter the concept of so-called digital literacy. Digital technologies are constantly evolving in this field and play an important role in human life. They are important not only in the labor market but also in education and human skills development. Digital technologies are thus one of the means by which we can develop the cognitive processes of visually impaired people. We can thus help them to improve a number of areas that are limited due to loss or reduction of visual perception. Especially, thinking, memory, and creating ideas are very important. This contribution was created within the solution of the project TAČR – Reduction of information deficit and development of the imagination of visually impaired people through 3D models with auditory elements in cooperation with the project PIGŽU – Support of information literacy of pupils and teachers. The first of the projects aims to reduce the information deficit caused by the loss or reduction of visual perception in visually impaired people using multisensory action. At the same time, it aims to develop their spatial imagination. The second project then focus on the creation of digital aids, which aims primarily at the development and support of computational thinking. In addition to mainstream primary school pupils, the project also focuses on pupils with special educational needs, including visually impaired individuals. The main output of the project is the creation of aids, including methodologies, using digital technologies. These are technologies such as Ozobot, Blue-Bot, or Bee-bot. The aim of the paper is to acquaint with the project, to provide at least basic information about digital technologies, and especially to describe the possibilities of personality development, skills, and abilities using these technologies in visually impaired students.

International audience; A novel approach depicting the dynamics of marijuana usage to gauge the effects of peer influence in a school population, is the site of investigation. Consumption of drug is considered as a contagious social epidemic which is spread mainly by peer influences. A relation-based graph-CA (r-GCA) model consisting of 4 states namely, Nonusers (N), Experimental users (E), Recreational users (R) and Addicts (A), is formulated in order to represent the prevalence of the epidemic on a campus. The r-GCA model is set up by local transition rules which delineates the proliferation of marijuana use. Data available in [4] is opted to verify and validate the r-GCA. Simulations of the r-GCA system are presented and discussed. The numerical results agree quite accurately with the observed data. Using the model, the enactment of campaigns of prevention targeting N, E and R states respectively were conducted and analysed. The results indicate a significant decline in marijuana consumption on the campus when a campaign of prevention targeting the latter three states simultaneously, is enacted.

Consumers often anthropomorphize non-human entities. In this research, we investigate a novel antecedent of anthropomorphism: language. Some languages (e.g., English) make a grammatical distinction between humans (he, she) and non-humans (it), whereas other languages (e.g., French) do not (all objects are gender-marked). We propose that such grammatical structures of languages influence the way individuals mentally represent non-human entities, and as a result, their generalized tendencies to anthropomorphize such entities. Across 10 studies, we provide evidence that speakers of languages that do not grammatically distinguish between humans and non-humans (it-less languages) anthropomorphize more than do speakers of languages that do make this distinction (non-it-less languages). We demonstrate the effects across natural languages (French, Turkish, English) and by manipulating grammatical gender. We show that the effects are observable in naturally occurring consumer contexts (e.g., secondary sales data), and that gender-marking in it-less languages influences consumers’ interactions with brands, even though the gender-markings are semantically arbitrary, and that these effects occur nonconsciously. Our findings have implications for the broader debate on the extent to which language influences thought, and also suggest ways in which managers can leverage nonconscious grammatical anthropomorphism to influence consumer perceptions, attitudes, and behavior.

Visual Abstract, Binaural beating is a perceptual auditory illusion occurring when presenting two neighboring frequencies to each ear separately. Several controversial claims have been attributed to binaural beats regarding their ability to entrain human brain activity and mood, in both the scientific literature and the marketing realm. Here, we sought to address those questions in a robust fashion using a single-blind, active-controlled protocol. To do so, we compared the effects of binaural beats with a control beat stimulation (monaural beats, known to entrain brain activity but not mood) across four distinct levels in the human auditory pathway: subcortical and cortical entrainment, scalp-level functional connectivity and self-reports. Both stimuli elicited standard subcortical responses at the pure tone frequencies of the stimulus [i.e., frequency following response (FFR)], and entrained the cortex at the beat frequency [i.e., auditory steady state response (ASSR)]. Furthermore, functional connectivity patterns were modulated differentially by both kinds of stimuli, with binaural beats being the only one eliciting cross-frequency activity. Despite this, we did not find any mood modulation related to our experimental manipulation. Our results provide evidence that binaural beats elicit cross frequency connectivity patterns, but weakly entrain the cortex when compared with monaural beat stimuli. Whether binaural beats have an impact on cognitive performance or other mood measurements remains to be seen and can be further investigated within the proposed methodological framework.

This paper concerns the issue of survival modelling in the case of repeated events. In the modelling of this type of events, attention should be paid to the existence of dependence among the analysed durations, as well as the occurrence of unobserved heterogeneity. One of the ways to include these aspects in the analysis is to use models with random effects. The primary objective of this paper is to present the application of such models to analyse changes in the place of employment. The duration of individual periods of employment for the surveyed employees was modelled. The approach used made it possible to identify factors influencing decisions on job changes, but also to assess the risk of occurrence of events such as termination of employment, and to examine the impact of unobserved heterogeneity on the results of the estimations. W artykule został podjęty problem modelowania czasu trwania w przypadku powtarzających się zdarzeń. W modelowaniu tego typu zdarzeń należy zwrócić uwagę na występowanie zależności między analizowanymi czasami trwania, jak również nieobserwowalnej heterogeniczności. Jednym ze sposobów uwzględnienia w analizie tych aspektów jest wykorzystanie modeli z efektami losowymi. Głównym celem artykułu jest zaprezentowanie możliwości wykorzystania tego typu modeli do analizy zmian miejsc zatrudnienia. Modelowaniu poddano czas trwania poszczególnych okresów zatrudnienia dla badanych jednostek. Wykorzystane podejście umożliwiło identyfikację czynników wpływających na decyzje o zmianie miejsca zatrudnienia, ocenę ryzyka wystąpienia zdarzenia, jakim jest rozwiązanie stosunku pracy, oraz zbadanie wpływu nieobserwowalnej heterogeniczności na wyniki przeprowadzonych estymacji. This study has been prepared as part of a project funded by the National Science Centre, Poland, entitled “The modeling of parallel family and occupational careers with Bayesian methods” (2015/17/B/HS4/02064).

Son preference is common in many Asian countries. Though a growing body of literature examines the drivers and socioeconomic impacts of phenomenon in case of China and India, work on other Asian countries is scarce. This study uses nationally representative survey of over 13 thousand households from Pakistan (PDHS 2012-13) to analyze the effects of observed preference for sons on women’s participation in intra-household decision-making. Four key intra-household decisions are considered: decisions regarding healthcare, family visits, large household purchases and spending husband's income. These correspond to four categories of household decisions, namely healthcare, social, consumption and financial. Probit and Ordered Probit are employed as the main estimation techniques and other determinants of household decision-making are controlled for. Besides, a number of matching routines are employed to account for the possibility of potential selection bias.We find that women with at least one son have more say in household decisions. Bearing at least one son is associated with 5%, 7% and 5% higher say in decisions involving healthcare, social and consumption matters respectively. Women's role in financial affairs, however, does not differ significantly from women with no sons. Female participation in decisionmaking grows significantly with the number of sons but only up to the third parity. These results are particularly visible among younger, wealthier and educated women, and those who got married earlier. The findings suggest a limited improvement in women's bargaining power at home resulting from the birth of one or more sons. This in part explains higherdesire for sons expressed by women compared to men in household surveys.; La préférence pour les garçons est courante en asie. Alors que beaucoup d’étudess’intéressent aux facteurs et aux impacts socioéconomiques de ce phénomène en Chine et enInde, les travaux sur les autres pays asiatiques sont plus rares. A partir d’une enquêtenationale réalisée sur plus de 13 000 ménages pakistanais (PDHS 2012-13), cette étudeanalyse les effets de la préférence pour les garçons sur la participation des femmes auxdécisions prises dans le ménage. Quatre décisions importantes du ménage seront prises encompte : celles relatives aux soins de santé, aux visites de famille, sur les achats du ménage etsur l’affectation des dépenses des revenus du mari. Celles-ci représentent quatre catégoriesdes décisions au sain du ménage : les décisions lié à la santé, aux liens sociaux, à laconsommation et aux affaires financières. Les méthodes Probit et Probit Ordinal sontutilisées pour les estimations de base et d’autres déterminants liés aux décisions prises dans leménage seront pris en compte. De plus, méthodes d’appariment sont utilisées pour tenircompte d’éventuels biais de sélection.Les résultats indiquent que le fait d’avoir au moins un fils a une influence sur les décisions duménage. Le fait d’avoir au moins un fils est associé à une hausse de 5%, 7% et 5% sur lesdécisions impliquant respectivement les soins de santé, les relations sociales et laconsommation. L’implication des femmes dans les finances du ménage ne varie pourtant passignificativement avec celle des femmes sans fils. La participation des femmes dans les prisesde décision augmente avec le nombre de fils mais seulement jusqu’à 3 garçons. Ce résultatentraine une amélioration relative sur le pouvoir de négociation des femmes au sein duménage suite à la naissance d’un ou plusieurs garçons. Cela explique en partie le désir plusfort des femmes d’avoir des fils par rapport aux hommes, selon les enquêtes ménages.

Objectives Our objective was to evaluate the effectiveness of peer-led self-management education in improving glycaemic control in patients with type 2 diabetes in a low-income country (Mali). Methods We conducted an open-label randomised controlled trial. A total of 151 adults (76% women, mean age 52.5) with type 2 diabetes (HbA1c≥8%), treated in the diabetes consultation units of two secondary health centres in Bamako, were allocated to peer-led structured patient education (n = 76) or conventional care alone (n = 75). The intervention group received 1 year of culturally tailored structured patient education (3 courses of 4 sessions) delivered in the community by five trained peer educators. Both groups underwent conventional diabetes monitoring and follow-up. Primary outcome was the mean absolute change in HbA1c from baseline to 12 months. Results 177 education sessions were delivered to the intervention group. Patient attrition was 8%. From baseline to 12 months, the decrease in HbA1c levels was 1.05% (SD = 2.0; CI95%: 1.54;-0.56) in the intervention group compared with 0.15% (SD = 1.7; CI95%: -0.56; 0.26) in the control group, p = 0.006. Mean BMI change was -1.65 kg/m2 (SD = 2.5; CI95%: -2.25; -1.06) in the intervention group and +0.05 kg/m2 (SD = 3.2; CI95%: -0.71; 0.81) in the control group, p = 0.0005. Mean waist circumference decreased by 3.34 cm (SD = 9.3; CI95%: -5.56;-1.13) in the intervention group and increased by 2.65 cm (SD = 10.3; CI95%: 0.20; 5.09) in the control group, p = 0.0003. Conclusions Peer-led structured patient education delivered over 1 year to patients with poorly controlled type 2 diabetes in Mali yielded substantial improvements in glycaemic control and anthropometric parameters. This is of importance for the scaling up of efficient interventions in low-resource settings in the future. Trial registration ClinicalTrials.gov NCT01485913

International audience; In Madagascar, a country where over 60% of deliveries are not attended by a healthcare professional, late or inadequate responses to complications during childbirth account for a great number of maternal deaths. In this article, we analyse local perceptions of birth-related risks and strategies used to avoid these risks or manage complications of childbirth. We conduct this analysis in light of the social meanings of childbirth and the social expectations placed upon women in a context of socioeconomic vulnerability and a challenged public health system. We conducted two separate studies in the district of Morondava (Menabe region) in June 2014 and March 2015, comprising semi-directive interviews with 111 people (59 mothers, 18 members of their immediate en-tourage and 34 institutional or healthcare stakeholders), and eight focus groups discussions-two with community leaders, and six with fathers. The results show that the social pressure exerted on women to give birth without complications leads them to practices aimed at avoiding a "big" baby including dietary restrictions, physical activity, and refusal of iron supplementation intake. During pregnancy, women are usually accompanied by a traditional birth attendant or matron (reninjaza). Further, they use the public health system by attending antenatal consultations. However, women are reluctant to deliver in a health facility, where the practices of health professionals are in discordance with the social realities of women and local beliefs around childbirth. If complications arise, they are explained by social causes. The parturient woman is only taken to a healthcare facility after carrying out rituals and if the problems do not resolve themselves. These findings support recommendations to reduce the cultural distance between health workers and childbearing women, strengthen the collaborations with reninjazas, and inform women and their decision makers (mother, reninjaza, spouse) about nutrition during pregnancy and signs of complications.

The COVID-19 pandemic brought significant changes to the usual rhythm of life. Reduced opportunities to meet with family members and friends in a situation of heightened stress leads to increased feelings of loneliness and social isolation, as well as increases the risk of mental health problems. The aim of this paper is to evaluate the effect of social contacts on the changes in psychoemotional states in the elderly population in Latvia during the crisis caused by the COVID-19 pandemic. The analysis draws upon quantitative data collected by the Survey of Health, Ageing and Retirement in Europe within Wave 8 in Latvia (n=1207). Measurements of the frequency of social contacts were used to construct social isolation indexes. Changes of psychoemotional state, characterized by sleeping problems, nervousness, frustration during the pandemic were included as dependent variables in multinomial logistic regression models that were run to identify the effect of social isolation on psychoemotional health in the context of other factors: age, gender, perceived health status, affluence and feelings of loneliness. The results show that in the group of those aged 50+, close to one-fifth of respondents experienced the effect of the COVID-19 crisis on their mental health. The link between reduced social contacts and changes in psychoemotional states proved to be statistically significant. In the group with the highest level of social isolation, irregularities in psychoemotional health are three times higher compared to other groups.

The purpose of this research was to develop the Anomia Questionnaire (AQ), which measures different dimensions of anomia and is based on the Levina, Martinsone, and Kamerade (Ļevina, Mārtinsone, & Kamerāde, 2015c, 2016a) integrative multidimensional model of anomia, as well as to determine its psychometric properties. The AQ was developed in Latvian. The sample consisted of 210 Latvian inhabitants aged from 19 to 58 years (27.6 % male, 72.4 % female). The factorial validity of the AQ was established using principal components analysis with Varimax rotation; this yielded six factors, which can be interpreted as Social Distrust (C1), Lack of Goal Clarity (C2), Generalized Sense of Meaninglessness (C3), Cultural Isolation (C4), Deviation from Prescribed Rules or Customs (C5), and Estrangement to Others (C6). All the AQ scales had high internal consistency (Cronbach’s alpha varied from .73 to .86). The reaction and discrimination indices satisfied the accepted psychometric criteria. The further stage of the AQ development would be the confirmatory factor analysis in broader international sample, the concurrent and convergent validity establishing, and test-retest reliability examination.

This paper presents an analysis of four case studies in order to elaborate the theory of functional music therapy. In the Czech Republic, the practices of functional music therapy are often used as a type of complementary rehabilitation. Although functional music therapy is based on sound and scientifically substantiated bases, practical applications lack comprehensive and systematic methodology. The aim of this paper is to deepen the knowledge of the links between the application of musical practices and functional development. On the basis of an interpretative approach to case studies (using a content analysis) we identified the objectives in the motor area, types of musical activities, and music therapy practices in persons with cerebral palsy. We also analysed the correlation between therapeutic objectives and musical activities, and set out methodological principles of their application. The outcomes of this study were compared with the results of a previous study by the author focusing on persons with severe multiple disabilities in order to develop a comprehensive theory of functional music therapy. Concerning the results of this comparison, this paper discusses the impact of intellectual disability on the flexibility of application of musical activities during functional training.

Research summary: Limited attention has been paid to the crucial role of individuals' motivation and social interactions in capability development. Building on literature in social psychology and behavioral economics that links heterogeneity in individual social motives to social interactions, we explain how the variation, selection, and retention processes underlying a group's deliberate capability development are affected by the composition of the group in terms of individuals' social motives in interplay with the organizational-level motivational levers designed by managers. Our multilevel theoretical model suggests that individual-level heterogeneity leads to the development of capabilities along different paths. For practice, this implies that, according to the composition of the group in terms of social motives, capabilities are more or less technically and evolutionary adequate and a source of business process performance. Managerial summary:We propose that when a group of employees engages in developing one of the firm's capabilities, capability development will follow a different path according to what motivates most of the employees composing the group. We identify and discuss three paths. Two of these paths (convergence and congruence) can help improve business process performance in a stable environment, the third one (open-ended) in a dynamic environment. Our work invites managers to not only think in terms of more or less capability development, but also in terms of capability development path(s): the path(s) in which groups in the firm are currently engaged and the one(s) that are desirable given the firm's objectives and the nature of the environment(s) the firm faces in deploying its business processes.

Background: The study of the attentional system remains a challenge for current neuroscience. The “Attention Network Test” (ANT) was designed to study simultaneously three different attentional networks (alerting, orienting, and executive) based in subtraction of different experimental conditions. However, some studies recommend caution with these calculations due to the interactions between the attentional networks. In particular, it is highly relevant that several interpretations about attentional impairment have arisen from these calculations in diverse pathologies. Event related potentials (ERPs) and neural source analysis can be applied to disentangle the relationships between these attentional networks not specifically shown by behavioral measures. Results: This study shows that there is a basic level of alerting (tonic alerting) in the no cue (NC) condition, represented by a slow negative trend in the ERP trace prior to the onset of the target stimuli. A progressive increase in the CNV amplitude related to the amount of information provided by the cue conditions is also shown. Neural source analysis reveals specific modulations of the CNV related to a task-related expectancy presented in the NC condition; a late modulation triggered by the central cue (CC) condition and probably representing a generic motor preparation; and an early and late modulation for spatial cue (SC) condition suggesting specific motor and sensory preactivation. Finally, the first component in the information processing of the target stimuli modulated by the interaction between orienting network and the executive system can be represented by N1. Conclusions: The ANT is useful as a paradigm to study specific attentional mechanisms and their interactions. However, calculation of network effects is based in subtractions with non-comparable experimental conditions, as evidenced by the present data, which can induce misinterpretations in the study of the attentional capacity in human subjects. Ministerio de Economía y Competitividad PSI2010- 16825

http://search.ebscohost.com/login.aspx?direct=true&db=bth&AN=83483955&site=ehost-live; International audience; Consumers' tendency to choose the option in the center of an array and the process underlying this effect is explored. Findings from two eye-tracking studies suggest that brands in the horizontal center receive more visual attention. They are more likely to be chosen. Investigation of the attention process revealed an initial central fixation bias, a tendency to look first at the central option, and a central gaze cascade effect, progressively increasing attention focused on the central option right prior to decision. Only the central gaze cascade effect was related to choice. An offline study with tangible products demonstrated that the centrally located item within a product category is chosen more often, even when it is not placed in the center of the visual field. Despite widespread use, memory-based attention measures were not correlated with eye-tracking measures. They did not capture visual attention and were not related to choice.

Background APOE is the biomarker with the greatest known influence on cognitive function; however, the effect of complex haplotypes involving polymorphisms rs449647, rs405509, rs440446, rs429358 and rs7412 has never been studied in older populations. Methods We evaluated APOE polymorphisms using multiplex PCR for genotyping and Mini-Mental State Examination (MMSE) to evaluate cognitive function in 819 individuals from VA Normative Aging Study. Results Combinatorial analysis of all polymorphisms and individual analysis of polymorphisms rs449647, rs405509, rs440446 and rs7412 did not show any association with cognitive performance. Polymorphism rs429358 was associated with better cognitive performance (odds of MMSE ≤ 25 = 0.63, 95% CI 0.42-0.95; p = 0.03) in the oldest subsample (5th quintile of age) (odds of MMSE ≤ 25 = 0.34; 95% CI 0.13-0.86; p = 0.02). APOE allele ε4 was also associated with better cognitive performance (odds of MMSE ≤ 25 = 0.61, 95% CI 0.40-0.94; p = 0.02), also in the oldest subsample (odds of MMSE ≤ 25 = 0.35, 95% CI 0.14-0.90; p = 0.03). Conclusions These results suggest a beneficial effect of polymorphism rs429358 in the oldest men. Electronic supplementary material The online version of this article (doi:10.1186/s12888-014-0223-x) contains supplementary material, which is available to authorized users.