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Your search keyword '"Khachatryan, Naira"' showing total 2 results
Start Over Author "Khachatryan, Naira" Language english Publisher oxford university press / usa
2 results on '"Khachatryan, Naira"'

1. Concomitant Treatment of Chronic Hepatitis C With Direct-Acting Antivirals and Multidrug-Resistant Tuberculosis Is Effective and Safe.

Author

Melikyan, Nara, Huerga, Helena, Atshemyan, Hakob, Kirakosyan, Ohanna, Sargsyants, Narina, Aydinyan, Tsovinar, Saribekyan, Nora, Khachatryan, Naira, Oganezova, Izabella, Falcao, Joana, Balkan, Suna, and Hewison, Cathy

Subjects
CHRONIC hepatitis C, MULTIDRUG-resistant tuberculosis, ANTIVIRAL agents, HEPATITIS C virus, DIRECTLY observed therapy
Abstract

We assessed effectiveness and safety of concomitant chronic hepatitis C virus (HCV) treatment with direct-acting antivirals (DAAs) and multidrug-resistant tuberculosis (MDR-TB). Of 322 MDR-TB patients (19.4% HCV), 30 were treated concomitantly (23.3% human immunodeficiency virus-positive). Overall, 76.7% achieved HCV treatment success (95.8% among tested). One patient (3.3%) experienced a serious adverse event. [ABSTRACT FROM AUTHOR]

Published
2021
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2. Culture Conversion at 6 Months in Patients Receiving Delamanid-containing Regimens for the Treatment of Multidrug-resistant Tuberculosis.

Author

Seung, Kwonjune J, Khan, Palwasha, Franke, Molly F, Ahmed, Saman, Aiylchiev, Stalbek, Alam, Manzur, Putri, Fauziah Asnely, Bastard, Mathieu, Docteur, Wisny, Gottlieb, Gary, Hewison, Catherine, Islam, Shirajul, Khachatryan, Naira, Kotrikadze, Tinatin, Khan, Uzma, Kumsa, Andargachew, Lecca, Leonid, Tassew, Yoseph Melaku, Melikyan, Nara, and Naing, Ye Yint

Subjects
ANTITUBERCULAR agents, IMIDAZOLES, MICROBIAL sensitivity tests, SPUTUM, TIME
Abstract

Delamanid should be effective against highly resistant strains of Mycobacterium tuberculosis , but uptake has been slow globally. In the endTB (expand new drug markets for TB) Observational Study, which enrolled a large, heterogeneous cohorts of patients receiving delamanid as part of a multidrug regimen, 80% of participants experienced sputum culture conversion within 6 months. Clinical Trials Registration. NCT02754765. [ABSTRACT FROM AUTHOR]

Published
2020
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