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Culture Conversion at 6 Months in Patients Receiving Delamanid-containing Regimens for the Treatment of Multidrug-resistant Tuberculosis.

Authors :
Seung, Kwonjune J
Khan, Palwasha
Franke, Molly F
Ahmed, Saman
Aiylchiev, Stalbek
Alam, Manzur
Putri, Fauziah Asnely
Bastard, Mathieu
Docteur, Wisny
Gottlieb, Gary
Hewison, Catherine
Islam, Shirajul
Khachatryan, Naira
Kotrikadze, Tinatin
Khan, Uzma
Kumsa, Andargachew
Lecca, Leonid
Tassew, Yoseph Melaku
Melikyan, Nara
Naing, Ye Yint
Source :
Clinical Infectious Diseases; 7/15/2020, Vol. 71 Issue 2, p415-418, 4p
Publication Year :
2020

Abstract

Delamanid should be effective against highly resistant strains of Mycobacterium tuberculosis , but uptake has been slow globally. In the endTB (expand new drug markets for TB) Observational Study, which enrolled a large, heterogeneous cohorts of patients receiving delamanid as part of a multidrug regimen, 80% of participants experienced sputum culture conversion within 6 months. Clinical Trials Registration. NCT02754765. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10584838
Volume :
71
Issue :
2
Database :
Complementary Index
Journal :
Clinical Infectious Diseases
Publication Type :
Academic Journal
Accession number :
144525355
Full Text :
https://doi.org/10.1093/cid/ciz1084