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Over the past decade or so, global warming has opened up the frozen waters of the Arctic Ocean in the summer months, prompting speculation that it would provide a shorter and faster sea route between Europe and Asia, thereby reducing the importance of the Indian Ocean as the 'key to the seven seas'. This article fact checks the reality of this assumption. [ABSTRACT FROM AUTHOR]

The Bahrain Medical Bulletin published an article titled "Talent in Medicine" by Dr. Anil Kumar Chawla. The article discusses how individuals in the medical profession have diverse talents and interests outside of medicine, such as music, art, writing, and sports. It also mentions that some medical professionals apply their knowledge to fields like clinical practice, pharmacology, and folk medicine. The article includes two poems titled "Why?" and "Zero is Hero!" and invites contributors to submit their literary works. This issue of the bulletin also commemorates 25 years since Dr. Chawla's poems were first published in the journal. [Extracted from the article]

The medical profession is not different from other workforce, sharing common interests, hobbies and talents. The majority of these activities are unrelated to medicine. Many are musicians, performers, artists, writers, critics, astronomers, photographers, etc., not to mention their excellence in the world of sports. On the other hand, there are also instances when the practice of these activities takes the form of applied interpretation of what they know in human pathobiology and the concerned function. Thus, some may be historians of clinical practice, clinical pharmacologists of locally used herbs or clinical therapists of locally practiced folk medicine. This section of the Bahrain Medical Bulletin will be devoted to "Talents in the Medical Profession" to show and exchange with others common interests and applied experience. Contributors are therefore welcomed to submit their literary works. [ABSTRACT FROM AUTHOR]

Background & objectives: Cervical cancer is a major health problem and a leading cause of death among women in India. Of all the associated risk factors, high-risk human papillomavirus (HPV) infections being the principal aetiologic agent, two HPV vaccines are in use for the control of cervical cancer. The present study was undertaken to explore the knowledge, attitude and practice (KAP) on HPV vaccination among the healthcare providers in India. Methods: A cross-sectional study was conducted among 590 healthcare professionals from 232 hospitals and 80 PHCs of nine districts of Delhi-NCR (National Capital Region). A total of 590 (526 female, 64 male) healthcare providers were surveyed. Results: Only 47 per cent of respondents recommended young women to get vaccinated against HPV. Majority of respondents (81%) were found to be aware about the existence of vaccines for cervical cancer prevention. District-wise, highest (88.3%) awareness about the existence of vaccines against HPV was reported from Gautam Budh Nagar and lowest (64%) in Faridabad. Although 86 per cent of gynaecologists were aware about the names of HPV vaccines available in the market, only 27 per cent of paramedical staff had this knowledge. There was a significant difference between the respondents from government and private sectors regarding their awareness about HPV vaccines. Lack of awareness about the principal cause, risk factors and symptoms for cervical cancer and HPV vaccination was significantly (P<0.05) reported in the respondents from paramedical staff category. Interpretation & conclusions: The findings reinforce continued medical education of healthcare providers, particularly those from the government sector on HPV vaccination for cervical cancer prevention. Public education is also pertinent for a successful HPV vaccination programme in the country. [ABSTRACT FROM AUTHOR]

The medical profession is not different from other workforce, sharing common interests, hobbies and talents. The majority of these activities are unrelated to medicine. Many are musicians, performers, artists, writers, critics, astronomers, photographers, etc., not to mention their excellence in the world of sports. On the other hand, there are also instances when the practice of these activities takes the form of applied interpretation of what they know in human pathobiology and the concerned function. Thus, some may be historians of clinical practice, clinical pharmacologists of locally used herbs or clinical therapists of locally practiced folk medicine. This section of the Bahrain Medical Bulletin will be devoted to "Talents in the Medical Profession" to show and exchange with others common interests and applied experience. Contributors are therefore welcomed to submit their literary works. This issue contains two poems titled "Get off the train!" and "T for tolerance!". [ABSTRACT FROM AUTHOR]

The poem "What's Happening?" by Anil Kumar is presented. First Line: When a 'yawn' or 'sneeze' comes, it comes; you can't stop it, Last Line: You allow or change what happens; don't stress over what happens!

Two poems by Anil Kumar Chawla are presented. "Our Sorrows." First Line: Man or woman, we've all encountered sorrow, Last Line: When I wear correct thinking glasses, distortion goes there is no sorrow. "Ground Zero." First Line: We are so impressed by levels of men and women - some dull some glow, Last Line: This world will be heaven we won't have to die to reach heaven's shores.

The poem "The 'I' Bug" is presented. First Line: Bugs of all kinds, you know, bite and cause disease, Last Line: 'I' bug.

The poem "It's Only Memory Dear" is presented. First Line: It's only your memory, dear! Last Line: You may live every days's every moment lightly, joyfully.

Two poems by Anil Chawla are presented. "Home." First Line: Home is where you come back and find rest, Last Line: It brings love and joy that emanates from this silence. "The Goalkeeper." First Line: When you were born, you didn't know a word, Last Line: restored within.

The poem "The Club Sixty" by Anil Kumar Chawla is presented. First Line: Happy birthday, so you are sixty now! Last Line: If you go with the flow, you'll live in happiness.

The liver is a major site of glucose, fatty acid, and triglyceride (TG) synthesis and serves as a major regulator of whole body nutrient homeostasis. Chronic exposure of humans or rodents to high-calorie diets promotes non-alcoholic fatty liver disease, characterized by neutral lipid accumulation in lipid droplets (LD) of hepatocytes. Here we show that the LD protein hypoxia-inducible gene 2 (Hig2/Hilpda) functions to enhance lipid accumulation in hepatocytes by attenuating TG hydrolysis. Hig2 expression increased in livers of mice on a high-fat diet and during fasting, two states associated with enhanced hepatic TG content. Hig2 expressed in primary mouse hepatocytes localized to LDs and promoted LD TG deposition in the presence of oleate. Conversely, tamoxifen-inducible Hig2 deletion reduced both TG content and LD size in primary hepatocytes from mice harboring floxed alleles of Hig2 and a cre/ERT2 transgene controlled by the ubiquitin C promoter. Hepatic TG was also decreased by liver-specific deletion of Hig2 in mice with floxed Hig2 expressing cre controlled by the albumin promoter. Importantly, we demonstrate that Hig2-deficient hepatocytes exhibit increased TG lipolysis, TG turnover, and fatty acid oxidation as compared with controls. Interestingly, mice with liver-specific Hig2 deletion also display improved glucose tolerance. Taken together, these data indicate that Hig2 plays a major role in promoting lipid sequestration within LDs in mouse hepatocytes through a mechanism that impairs TG degradation. [ABSTRACT FROM AUTHOR]