Search

Objective·To verify the accuracy and clinical feasibility of fluoroscopic stereophotogrammetric analysis (FSA) technology based on two dimension (2D)-three dimension (3D) registration for early migration detection of aseptic loosening of joint prostheses.Methods·2D-3D registration algorithms centering on the light source and projected object respectively in FSA technology were verified under various working conditions through image synthesis experiments, and the feasibility of clinical application was verified through real model experiments. The image synthesis experiment established a perspective projection environment with the same parameters as the real environment in a virtual environment, the 2D perspective images of the 3D model (bone or prosthesis) during the six degrees of freedom transformation were recorded, and the six degrees of freedom transformation of the 3D model was restored by using different 2D-3D registration algorithms. The error of each registration algorithm was calculated. For real model validation, the migration between bone and prosthesis after joint replacement surgery was simulated with a high precision bone prosthesis migration simulator. The 3D model of the bone or prosthesis was reconstructed by using computed tomograph (CT) images and optical scanning, and the 2D perspective images before and after prosthesis migration were captured by using a fluoroscopy device. The migration of the prosthesis was restored by using FSA technology based on 2D-3D registration, and the error of FSA technology was calculated.Results·The accuracy of the 2D-3D registration algorithm centering on the light source was higher than that of the algorithm centering on the projected object under different working conditions. When the initial registration conditions were favorable, the algorithm centering on the light source reduced the rotation error compared to the algorithm centering on the projected object, with a statistical difference (P=0.021), and the displacement error decreases, with a significant statistical difference (P=0.000). Moreover, algorithms centering on the light sources required lower similarity and fewer registration times to meet clinical application requirements.Conclusion·The accuracy of FSA technology based on 2D-3D registration in early migration detection of artificial joint prostheses meets clinical application requirements. This technology can warn of late aseptic loosening of prostheses by detecting early migration of prostheses after joint replacement surgery, and is expected to be applied to clinical practice through further research.

[Introduction] In order to improve heat exchange efficiency, the condensate pipelines, main water supply pipelines drain pipelines and partial extraction pipelines of nuclear power plants are all coated outside the pipelines. At present, the test methods of ferromagnetic pipelines are mainly conventional ultrasound and ultrasonic guided waves. These test methods are limited by the detection environment and preconditions, which increase the difficulty of test. In order to improve the test efficiency of pipelines with insulation layer, we shall enrich technical methods, shorten maintenance period and improve economic benefit of nuclear power plant. [Method] This paper mainly studied the feasibility and reliability of pulsed eddy current testing method under low frequency electromagnetic interference in nuclear power plant, and used the measured and calculated values of the induced voltage to establish the optimal parameter inversion problem. In combination with the coupling relationship between the parameters and based on the time-domain analytical solution of the pipeline pulsed eddy current field, the paper established the specific relationship between the measured value and the calculated value of the induced voltage, and established the optimization parameter inversion problem. In combination with the coupling relationship between the parameters, the paper proposed a pulsed eddy current detection method for in-service operation and maintenance of insulated pipes in nuclear power plants. [Result] Using the pulsed eddy current detection method for the relative wall thickness of ferromagnetic pipelines proposed in this paper, in-service sample pipelines of nuclear power plant are tested and the testing result is compared with conventional ultrasonic testing. The error of the two testing results is about 5%. [Conclusion] The testing results of impulse eddy current testing are reliable and it is suitable for non-destructive testing and evaluation of nuclear power plant ferromagnetic pipeline wall thickness corrosion thinning.

[Introduction] In the nuclear power plant, the steam pipeline is generally installed with an insulation layer on the outer wall to improve heat transfer efficiency. Currently, the main detection means for ferromagnetic pipelines are conventional ultrasound and ultrasonic guided waves. Prior to the inspection, the insulation layer on the outer wall of the pipeline needs to be removed, leading to extended inspection time, increased labor costs, and an inability to meet the requirements for high-quality development in nuclear power plants. The application of the pulsed eddy current (PEC) technique for nuclear power plants can eliminate the need for insulation layer removal, enabling non-stop online screening. The defects testing by coil placement is an essential indicator of the PEC technique. [Method] In this paper, the modeling and simulation of the pipelines was conducted by applying ANSYS Maxwell, coaxial and vertical detection coils were designed respectively to simulate the detection capability of PEC on flat bottom defects with consistency in the lift-off distance, materials and other conditions. Sample pipes were selected from the nuclear power plant for coaxial and vertical PEC testing. The pulsed eddy current testing (PECT) results were cross-validated with ultrasonic thickness measurement, and the effects of two coil placement methods on PECT were compared. [Result] The results show that vertical coils are more effective in defect detection compared to coaxial coils. [Conclusion] The defects testing by coil placement has great significance for implementing PEC in the nuclear power sector.

ObjectiveTo observe the effects of a novel transcranial direct current stimulation (tDCS) device known as "Halo Sport" on pain and mood in patients with non-specific chronic low back pain (NSCLBP), by specifically targeting the bilateral primary motor cortex (M1 region).MethodsForty-two patients with NSCLBP who were treated in the Rehabilitation Medicine Department of Wuxi People's Hospital Affiliated to Nanjing Medical University from July 2023 to March 2024 were recruited. According to the random number table method, the patients were divided into control group and experimental group, with 21 patients in each group. During the course of treatment, one patient withdrew in each group and 20 patients were included in both groups. The experimental group received treatment using the new "Halo Sport" tDCS at 2.0 mA for 20 minutes with bilateral M1 anodes, followed by 45-minute exercise treatment, including 5 minutes of stretching exercises, 20 minutes of core training exercises, and 20 minutes of aerobic training exercises. The control group received sham tDCS in combination with exercise therapy. The treatment period for both groups was three days a week for four weeks. Before and after 4 weeks of treatment, the numerical rating scale (NRS) was used to evaluate pain intensity, the oswestry disability index (ODI) was used to evaluate lumbar dysfunction degree, while the pain catastrophizing scale (PCS), self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were used to assess related negative emotions.Results1) Pain intensity: After treatment, the NRS scores in the experimental and control groups significantly decreased compared with those at the baseline (PPPP>0.05). 3) Negative emotions: After treatment, both groups showed a significant decrease in PCS, SDS and SAS scores compared to the baseline (PP>0.05).ConclusionBilateral M1 area anodal tDCS with the Halo Sport device can significantly reduce pain in patients with NSCLBP. Whether combined with tDCS or not, exercise therapy can improve lumbar spine dysfunction and alleviate negative emotions in NSCLBP patients.

【Objective】 The Urumqi River is one of the most important rivers in northwestern China. The objective of this paper is to study the change in vegetation coverage in its basin and the underlying determinants in attempts to help improve its management. 【Method】 The study is based on the Landsat TM/OLI remote sensing imageries from 2000 to 2020. Spatiotemporal variations in vegetation coverage (FVC) in the basin during this period are extracted using the image dichotomy and vegetation cover transfer matrix, from which we analyze the changes in land use and topographic features in the basin. The factors that are responsible for the change in FVC in the basin are calculated using the geo-detector model, reclassification and other methods. 【Result】 From 2000 to 2020, vegetation coverage in the basin decreased first and then increased. Vegetation coverage was high in the upper reaches and low in the middle and low reaches. Vegetation coverage in different land usage was ranked in the order of forest land > cropland > grassland > construction land > water bodies > unused land. The change in vegetation coverage was influenced by topographic factors and fluctuated with elevation, with the vegetation coverage being the highest in elevations air temperature > elevation > surface temperature > precipitation > soil moisture > slope > slope direction. The results of the interaction detection analysis show that elevation-land use, land use-temperature are the coupling factors that influenced vegetation coverages more than coupling of other factors. 【Conclusion】 The average vegetation coverage in the Urumqi River basin varied from 0.348 to 0.456 in 2000—2020; it varied spatially. Overall, it is high in the upper reach and low in the middle and lower reaches. Variation in land use explains the variation in the vegetation coverage more than any other natural factors.

We designed an intelligent vehicle terminal based on UWB accurate positioning technology, which integrates multiple functions such as precise positioning, 4G/5G wireless communication, video monitoring, data acquisition, voice call and other functions. The intelligent vehicle terminal uses Android platform, takes ARM RK3399 as the control core and UWB communication transceiver chip DW1000 as the precise positioning core, realizing the precise positioning, intelligent scheduling, information collection, safety warning, voice call, human-computer interaction and other functions of the underground vehicle. The test results show that the maximum dynamic positioning error of the vehicle terminal is no more than 7.3 meters, which meets the functional requirements of the coal mine for intelligent auxiliary transportation.

ObjectiveTo establish a set of indicators for assessing the public health emergency response capacity at county/district level in China. MethodsAn indicator system for evaluating public health emergency response capacity at county/district level was initially formulated based on theoretical research and literature review. Three rounds of Delphi consultation were conducted among 18 senior professionals to determine the indicators and their weights of the system using hierarchical analysis method. ResultsFor the 3 rounds of expert consultation, the positive coefficients of the were 100.0%, 88.9%, and 88.9%; the expert authority coefficients were 0.87, 0.84, and 0.87; and the coordination coefficients of expert opinions were 0.207, 0.210, and 0.295 (all P < 0.001), indicating a good coordination of the experts′ opinions. The finally established indicator system for assessing public health emergency response capacity at county/district level included 5 first-, 19 second-, and 61 third-level indicators. For the third round of Delphi consultation, the experts′ mean scores and ranges of coefficients of variance for importance/feasibility of all the indicators were 4.83 ± 0.13/4.48 ± 0.21 and 0.00 – 0.18/0.07 – 0.22, respectively. The weights for the first-, second-, and third-level indicators ranged from 0.094 to 0.290, 0.011 to 0.119, and 0.001 to 0.087, respectively. ConclusionThe established indicator system could be used to develop tools for evaluating public health emergency response capacities at county/district level, while the reliability and validity of the indicator system need to be assessed further.

Objective: To explore the conditions of embedding diacylglycerol (DAG) with sodium casein (SC) and nano cellulose cellulose (NCC) as wall materials and improve the quality of functional fermented dairy products.Methods: Using milk fat as raw material, DAG was prepared by enzymolysis reaction. Using SC and NCC as wall materials, oil in water DAG emulsion was prepared. The addition amount of SC and NCC, particle size and homogeneous pressure of the emulsion under optimal preparation conditions were screened, and rheological analysis, texture analysis and sensory analysis were conducted on soft cheese with DAG nano-emulsion added. The stability difference between them was investigated and soft cheese was prepared as a fat substitute. Results: The optimum conditions for preparing sodium caseinate cellulose DAG lotion by the high-pressure homogenization method were as follows: NCC content 1.5%, SC content 5%, core wall ratio 1:1, homogenization pressure 100 MPa. All lotions are oils in water with particle sizes between 100~240 nm. By analyzing the characteristics of soft cheese, with the addition of DAG lotion, the elasticity of soft cheese increased, and the hardness, consistency, and cohesiveness all increased at first and then decreased. When the addition of lotion was 2%, the sensory quality was significantly higher than in other groups. Conclusion: In the NCC content of 1.5%, SC content of 5%, core wall ratio of 1:1, under the conditions of homogenization pressure of 100 MPa, DAG could be effectively embedded, and the embedding rate could reach 77.9%. When 2% DAG lotion was added to soft cheese, the sensory quality of the soft cheese could be significantly improved.

For exploring the effects of yttrium oxide and chromium oxide particles on the properties of pure aluminum micro-arc oxide films，micro-arc oxide films were prepared on the surface of 1060 industrial pure aluminum by micro-arc oxidation technology in the phosphateelectrolytic liquid system with yttrium oxide and chromium oxide as additives.Scanning electron microscopy (SEM)，X-ray diffraction (XRD)instrument，eddy current thickness meter，microhardness meter，step profiler，friction and wear testing machine，and electrochemical method were employed to characterize the surface morphology，phase composition，thickness，hardness，roughness，wear resistance and corrosion resistance.Results showed that compared with the film prepared with the addition of 2.5 g/L Y2O3 or 2.5 g/L Cr2O3 alone，the composite film prepared by adding 2.5g/L Y2O3 and 2.5g/L Cr2O3 possessed fewer holes on the surface，more compact surface and better wear resistance，with a microhardness of 746 HV，a thickness of 20.1 μm and a roughness of 2 226.2 nm.Meanwhile，the composite film had the maximum self-corrosion potential，the minimum self-corrosion current density and the optimal corrosion resistance.

The refined description of the flow field information around a ship can provide feedback on the internal essence of the ship's macroscopic hydrodynamic performance from the perspective of the flow mechanism, and high-quality flow field measurement technology is a necessary means of ensuring such a refined description of the flow field. Based on the engineering requirements of ship flow field measurement, the current development status of flow field measurement technology is summarized according to its technical characteristics, and the applications and characteristics of each method are described in detail. The existing flow field measurement methods still have many problems that need to be solved. The exploration of hardware upgrading, technology integration, algorithm optimization, function expansion, data assimilation and machine learning may promote the rapid development of flow field measurement technology in the direction of comprehensiveness, specialization and efficiency.

Complex fracture network is easy to form after hydraulic fracturing in coalbed methane reservoir. In order to study the influencing factors of complex fracture conductivity, an improved proppant filling fracture conductivity tester was used to evaluate the effects of proppant particle size, sand concentration, coal elastic modulus, coal powder content and fracturing fluid type on complex fracture conductivity in coalbed methane reservoir. The results show that: under the same sand concentration, the conductivity of E-type fracture is significantly greater than that of T-type fracture and single fracture, that is, the more complex the fracture morphology is, the greater the conductivity is; the conductivity of ceramsite as proppant is significantly greater than that of coated sand and quartz sand; the higher the sand concentration is, the greater the elastic modulus of coal and rock is, the greater the conductivity of fracture is; coal powder and fracturing fluid have great influence on fracture conductivity. The higher the content of coal powder is, the higher the damage rate to fracture conductivity is. Guar gum fracturing fluid has the greatest damage to fracture conductivity, followed by clean fracturing fluid and active hydraulic fracturing fluid. In addition, the more complex the fracture morphology is, the more serious the damage degree of coal powder and fracturing fluid to fracture conductivity is.

This paper briefly introduces particle image velocimetry (PIV) technology and summarizes the R&D of algorithms for velocity field calculation in the PIV image treatment. More attentions are paid to various applications of PIV in ship experimental test, and elaborate on them from three aspects, including the flow fields around surface ships and underwater vehicles, as well as ship air flow fields. Finally, the direction for the R&D of PIV technology in ship fields is put forward. In terms of the speed measurement hardware system, PIV algorithms and ship flow field research, several problems requiring further study are highlighted, suggestions on the measurement of ship flow field are given. This study has certain reference and guiding significance for future research on flow field performance optimization.

Due to its large specific surface area, excellent penetration resistance and a large number of functional groups distributed on the surface, graphene oxide(GO) has become a research hotspot in the fields of anticorrosion, permeation separation and coating mechanical properties. The research progress of GO application on metal surface in recent years was reviewed. On the basis of domestic and foreign literature, the research progress of GO applied on metal surface for anticorrosion, permeation separation, mechanical properties of coating and other aspects was described, and the mechanism was summarized and analyzed. The anticorrosion mechanism is mainly the physical barrier effect of GO and its chemical inertness to the electroactive medium. The mechanism of osmotic separation is mainly the multi-layer pore structure and functional groups of GO. The main mechanism of mechanical properties of the coating is the good compatibility between GO and coating and the formation of chemical bond between surface functional groups and metal matrix. It was pointed out that there is still a lack of GO composite preparation technology that meets the requirements of environmental protection, low cost and large-scale industrialization, the technological parameters involved, the design of composite phase system and other aspects still need further study. It was also proposed to be applied to metal anticorrosion, oil-water separation and mechanical properties of coating, so as to solve the key problems such as corrosion resistance of metal surface, oil-water permeability and separation performance, bonding force between coating and metal substrate.

According to the inspiration of research on multi-granularity marker information system in rough set, for the formal background of multi-granularity marker, concept lattices made by different granularity markers have connections. This is the hotspot research in the formal concept analysis. In order to study connections between concept lattices in different granularity markers, this paper discusses the relation of extrema made by different granularity markers firstly. Then using the relation of extrema, this paper researches connections between object-oriented concept lattice in different granularity markers. Using the complementary relationship between the attribute-oriented concept lattice and the object-oriented concept lattice, this paper studies the relationship between the attribute-oriented concept lattices formed under different granularity markers, and realizes the formal background under the narrower granularity and the formal background under the wider granularity. The knowledge under coarse-grained markers is inferred from the knowledge under fine-grained markers. Finally, a corresponding concept lattice generation method is proposed.

In order to improve the safety and reduce interface impedance of lithium-ion batteries, the star-shaped polyhedral POSS-poly(methyl methacrylate) (POSS-(PMMA46)8), which has both excellent heat resistance and good compatibility with the polymer material, was selected as a modifier to modify the separator of commercial polypropylene (PP) by the method of impregnation. The micromorphology of the composite separator was studied by scanning electron microscope (SEM). The mechanical property of the separator was measured by a tensile tester. The thermal stability of the separator was studied at a high temperature. The wettability of the separator was tested by a contact angle tester. The AC impedance was used to obtain the bulk impedance of the composite separator and then its ionic conductivity was studied. The electrochemical stability of the separator was measured by linear sweep voltammetry (LSV). The results show that when the mass fraction of POSS-(PMMA46)8 is 40%, the pore distribution of the composite membrane is homogeneous, and the wettability is the best. The tensile strength is 5.34 times that of the original film, and the thermo-stability is ideal at 160℃/1h. The conductivity of the composite membrane is 1.35×10-3 S/cm. The interface resistance between the composite separator and the electrode is reduced from 743Ω to 152Ω, and which is 79.5% higher than that of the original film; for Li/Separator/LiFePO4 cell, the charge-discharge cycling stability is better and the battery capacity at low magnification is comparable to commercial PP separator.

Background and objective TCF-4 is an important downstream molecule of Wnt signaling pathway, but studies on the expression level and significance of TCF-4 in lung cancer were still limited. The aim of this study is to examine the expression level of TCF-4 in lung cancer tissues and cell lines, and analyze its relationship with clinicopathologic characteristics and biological behavior of lung cancers. Methods TCF-4 expression was examined in 120 lung cancer specimens and 10 corresponding normal lung specimens using immunohistochemistry (S-P method). Immunofluorescence was used to examine the TCF-4 protein expression level and subcellular localization in lung cancer cells and HBE (human normal bronchi epithelium) cells. Expression levels of TCF-4 mRNA were examined using transcription-polymerase chain reaction (RT-PCR) in 9 lung cancer cell lines. Results Among 120 lung cancer specimens, 96 samples showed high expression of TCF-4 (80.0%), including 37 samples showed TCF-4 expression both in cytoplasm and nuclei (30.8%), TCF-4 were not detected in 10 corresponding normal lung specimens. TCF-4 expression level was positively correlated with TNM stages (P=0.022). The fluorescence signal of TCF-4 protein was conspicuous in lung cancer cells, primarily in cell nuclei, but extremely low in HBE. TCF-4 mRNA expression levels were incompatible in different histology types, the expression level of TCF-4 was relatively high in giant cell carcinoma cells, but low in lung adencarcinoma cells. Conclusion High expression of TCF-4 positively correlated with lung cancer progression.

Studying the soil stoichiometric ratios and the influencing factors of different altitude gradients in mountain ecosystems in arid zones is significant in revealing the soil nutrient status and maintaining the sustainable development of mountain ecosystems. In this paper, 13 sample plots were established along the elevation gradient in the mountains of the southern Ili River Valley, and soil in the depth of 0-20 cm was studied to investigate nutrient stoichiometric ratios and their influencing factors. The results showed that: (1) Soil acidity gradually increased with elevation. Organic carbon and total nitrogen contents are significantly higher in the middle and high mountain belts than in the low mountain belts, while total phosphorus and total potassium contents are opposite. (2) Due to altitudinal differences, the carbon-to-nitrogen ratio is significantly higher in the mid-alpine belt than in the low and alpine belts; carbon and phosphorus ratios are significantly higher in the middle and high mountain belts than in the middle and low mountain belts; carbon and potassium ratios are significantly higher in the middle and high mountain belts than in the low mountain belts; nitrogen-phosphorus ratios are higher in the alpine zone, but there is no major difference between the transition zone and the low mountain zone; nitrogen-potassium ratios are much higher in the alpine zone, whereas there is no significant difference between the mid-alpine zone and the transition zone; the differences of phosphorus/potassium ratios between altitudinal gradients are ignorable. (3) The dominant factors affecting the stoichiometric ratios of soil physicochemical indicators are soil organic carbon (62.4%), total phosphorus (15.9%), and total carbon (13.7%); while the major environmental factors are mean annual soil temperature (27.1%), vegetation index (11.2%), elevation (12.3%), and mean annual atmospheric temperature (3.4%). The study showed that the physicochemical indicators have an important influence on the soil stoichiometric ratio, further verified that the altitude is still the dominant factor affecting the stoichiometric ratio, and revealed that the influence of microenvironmental factors on the soil stoichiometric ratio should not be neglected, which provides a scientific basis for the in-depth study of the nutrient status of soils in mountainous areas of the Ili River Valley. [ABSTRACT FROM AUTHOR]

Objective To collect extensively drug-resistant tuberculosis (XDR-TB) Mycobacterium tuberculosis strains isolated from Xi'an City between 2019 and 2020, and analyze the drug resistance patterns of XDR-TB strains to second-line anti-tuberculosis drugs and the occurrence of new defined extensively drug-resistant tuberculosis in Xi'an, in order to provide evidence for guiding clinical drug use of multidrug-resistant tuberculosis (MDR-TB) patients. Methods A total of 3 088 strains of Mycobacterium tuberculosis that underwent phenotypic drug susceptibility testing at Xi'an Chest Hospital from January 2019 to December 2020 were retrospectively selected to analyze the resistance of anti-tuberculosis drug. Among the stored MDR-TB strains, 114 strains of preserved multidrug-resistant Mycobacterium tuberculosis were randomly selected for bedaquiline and linezolid susceptibility testing. Combined with the results of previous second-line drug susceptibility testing, the incidence of newly defined extensive drug resistance was analyzed. Results Among the 3 088 Mycobacterium tuberculosis strains analyzed, 411 strains (14.3%) showed resistance to isoniazid, 347 strains (11.2%) showed resistance to rifampicin, 142 strains (4.6%) showed resistance to ethambutol, 550 strains (17.8%) showed resistance to streptomycin, and 237 strains (7.6%) exhibited multidrug resistance. Of 237 MDR-TB strains, the resistance rates of ethambutol, moxifloxacin, rifampicin, sodium para-aminosalicylate, prothioconazole, capreomycin, amikacin, and clofazimine were 44.3%, 26.6%, 33.3%, 24.1%, 5.1%, 4.2%, 3.0%, and 2.5%, respectively. Among the randomly selected 114 MDR-TB strains, none showed resistance to bedaquiline, three showed resistance to linezolid, and one strain met the new definition for extensively drug-resistant tuberculosis. Conclusion In Xi'an City, high rates of resistance among MDR-TB strains are observed for ethambutol, quinolone and sodium para-aminosalicylate, and the drug susceptibility tests should be obtained as much as possible when using these drugs. The incidence of new definition extensively drug-resistant tuberculosis is low, and bedaquiline and linezolid remain effective drugs for the treatment of multidrug-resistant tuberculosis even without drug susceptibility testing results. [ABSTRACT FROM AUTHOR]

Black pork is a very popular pork product in the market. Differing from ordinary large white pigs, black pork has high nutritional value, abundant unsaturated fatty acids, and high contents of inosinic acid and proteins, etc., exhibiting advantages such as rich mouthfeel and unique flavor thereby gaining high consumer popularity. There are many black pig breeds in China, and the flavors of pig breeds vary with different regions. On the basis of summarizing the general procedure for analyzing the flavor substances of meat products, the volatile flavor substances and tasting substances of the black pigs from seven regions, Dingyuan, Hebei (Baoxu), Laiwu, Yunnan, Beijing, Shanxi and Qinghai (Bamei), were analyzed and summarized in this paper, with the white pig as a reference. The key flavor substances of the black pork samples from different regions were determined. Based on the formation pathways of aroma-active and taste-active substances of the black pork, the main reasons responsible for the flavor differences among the black pigs from different regions were analyzed. Future research directions were put forward, so as to provide a theoretical reference for selective development of specific black pork processed products and value exploration of specific black pork varieties in certain regions. [ABSTRACT FROM AUTHOR]

Objective To investigate the effect of resistance exercise on self-management ability, vascular diastolic function and atherosclerosis in patients with hypertension. Methods A total of 160 patients with hypertension treated in Sinopharm Dongfeng General Hospital from December 2019 to January 2022 were enrolled in this study. Patients were divided into study group (n=80) and traditional group (n=80) by random number table method. The traditional group was given routine aerobic exercise training based on drug therapy, and the research group was given resistance exercise training based on traditional therapy. Patients in both groups received intervention for 3 months, and the changes of vascular endothelial diastolic function and atherosclerosis were compared and analyzed before and after training. Results After training , the systolic blood pressure and diastolic blood pressure of the two groups decreased significantly compared with those before training (P＜0.05), and the study group was significantly lower than the traditional group (P＜0.05). The scores of self-management ability (45.28±3.17, 40.10±2.22) in the study group and traditional group were significantly higher than those before training (31.48±3.18, 31.54±2.58); The score of self-management ability in study group was significantly lower than that in traditional group (t=141.972, P＜0.05). The serum levels of lipoprotein-associated phospholipase 2 (Lp-PLA2) and homocysteine (Hcy) in two groups decreased significantly compared with those before training (P＜0.05)，and the levels of serum Lp-PLA2 and Hcy in the study group were significantly higher than those in the traditional group (P＜0.05). The change rate of artery diameter and the change rate of artery diameter of endothelium-dependent vasodilation function in the two groups were significantly higher than those before training, and the study group was significantly higher than the traditional group (P＜0.05). There was no significant difference in carotid intima-media thickness between the two groups after training and before training, and there was no significant difference between the study group and the traditional group (P＞0.05). Conclusion Resistance exercise can improve vascular endothelial relaxation function and atherosclerosis status, inhibit the expression of Lp-PLA2 and Hcy, reduce blood pressure continuously, and improve the self-management ability of patients with hypertension.

Objective To investigate the effects of melatonin (MT) on oxidative stress and expression of apoptosis marker protein in human umbilical vein endothelial cells (HUVECs) induced by hydrogen peroxide (H2O2). Methods HUVECs were divided into blank group and H2O2 (100, 200, 300, 400, 600, 700 mmol/L) groups.CCK8 method was used to select the best concentration for modeling. To clarify the effect of melatonin on oxidative stress injury caused by H2O2, HUVECs were divided into control group, H2O2 group and melatonin group. Western blot was used to detect the expression of p-p65/p65, SOD2 and cleaved-caspase 3. The activity of super-oxide dismutase (SOD), the concentration of malondialdehyde (MDA) and catalase (CAT) were measred by commercially available kits. Reactive oxygen species (ROS) staining was used to detect ROS content in HUVECs. Results H2O2 increased the expression of p-p65/p65 and cleaved-caspase 3(P＜0.001), decreased the expression of SOD2(P＜0.05)its biological activity(P＜0.001) and the concentration of CAT(P＜0.01), elevated the concentration of MDA(P＜0.001) and the level of ROS(P＜0.001)in HUVECs. Compared with H2O2 group, MT treatment decreased the expression of p-p65/p65(P＜0.001), SOD2(P＜0.001)and cleaved-caspase 3(P＜0.01), increased the expression of SOD2(P＜0.001)as well as biological activity of SOD(P＜0.001) and the concentration of CAT(P＜0.05) reduced the concentration of MDA(P＜0.001) and the level of ROS(P＜0.001)in HUVECs. Conclusions Melatonin plays a protective role in oxidative stress injury of HUVECs induced by H2O2 through up-regulating the expression of SOD2 and down-regulating the expression of p-p65/p65 and cleaved-caspase 3.

BackgroundThe existing tools in China for assessing psychiatric nurses' knowledge， attitude and practice towards the use of protective restraint do not sufficiently consider the specialty in psychiatric practice， and the scale items are somewhat cumbersome to use， which together restrict their further promotion and application. Accordingly， there is an urgent need for developing a more scientific assessment tool.ObjectiveTo construct a scale for assessing psychiatric nurses' knowledge， attitude and practice towards the use of protective restraint and to verify its reliability and validity， so as to provide a generic tool for the assessment.MethodsBased on the theoretical framework of the knowledge-attitude-practice model， the preliminary scale was formed through systematic literature review， qualitative interview and Delphi method. From July to December 2021， a stratified sampling was utilized to select 729 psychiatric nurses from tertiary， secondary and primary （including unclassified medical institutions and grassroots hospitals） psychiatric hospitals in Guangdong Province. The formal scale was developed through item analysis， exploratory factor analysis and confirmatory factor analysis. The validity of the scale was evaluated by content validity and structure validity， and the reliability was verified by procedures including Cronbach's α coefficient， test-retest reliability， and split-half reliability.ResultsA total of 12 items of three dimensions （knowledge， attitude， practice） were included in the scale for assessing psychiatric nurses' knowledge， attitude and practice towards the use of protective restraint. The scale-level content validity index （S-CVI） was 0.941， and the item-level content validity index （I-CVI） ranged from 0.812 to 1.000. Exploratory factor analysis extracted three common factors， and the cumulative variance contribution rate was 62.948%. The confirmatory factor yielded adequate fit. Cronbach's α coefficient was found to be 0.887 for the scale， 0.819 for knowledge dimension， 0.842 for attitude dimension， and 0.831 for practice dimension. The split-half reliability and test-retest reliability for the scale were 0.712 and 0.922， respectively.ConclusionThe scale shows satisfactory reliability and validity， which can be used to assess psychiatric nurses' knowledge， attitude and practice towards the use of protective restraint. ［Funded by Guangdong Clinical Teaching Base Teaching Reform Research Project （number， 2021JD119）］

Objective·To explore the adaptation and adaptability of RUBI-PT (the Research Units in Behavioral Intervention Autism Network Parent Training) program in China.Methods·According to the four steps of cultural adaptation, the RUBI-PT program was adapted, including information collection, preliminary adaptation design, preliminary adaptation test and further adjustment. In the information collection phase, six pediatricians and two psychotherapists were invited to conduct six focus group interviews, and according to the expert opinions, the RUBI-PT program was preliminarily adapted from the aspects of language, treatment format and treatment setting. In the preliminary adaptation test phase, 16 parents of autism spectrum disorder (ASD) children were recruited and divided into two batches to participate in the online RUBI-PT. After the treatment, the project feedback questionnaires were collected, and the adaptability was investigated and analyzed. Finally, the scheme was further adjusted according to the test results.Results·The preliminary adaptation program of RUBI-PT was adjusted from individual training to group training, including eight core skills sessions, which were implemented in the form of online meetings. The preliminary test results showed that parents′ satisfaction with lesson progress, lesson process, completion of homework and comments to homework were 90%, 80%, 100% and 100%, respectively; in terms of the course difficulty, parents reported that the 7th session (functional communication training) and the 8th session (teaching skills) were the most difficult. Based on the above survey results and the opinions of the expert group, further adjustments were completed, and an adaptation program for localized RUBI-PT was ultimately formed.Conclusion·After adaptation and adaptability investigation, the RUBI-PT, which is suitable for Chinese families with ASD children to conduct behavioral parent training, has been formed.

Sepsis and concomitant multiorgan dysfunction are a group of common clinical syndromes, and their prevalence are increasing year by year due to the increase of the aging population. It reveals that 20 million cases of sepsis occur globally every year, with a mortality rate of 26%. Early diagnosis of sepsis facilitates the adoption of timely and targeted therapeutic strategies, which is a key element in reducing mortality. Endothelial cells (EC) are the early targets of exogenous pathogens and endogenous injury signals, and numerous studies suggest that structural changes and functional activation of EC play an important role in the development of sepsis. As an endothelial-exclusive signaling pathway, the angiopoietin (Ang)/tyrosine kinase receptor (Tie) signaling pathway plays an important role in the abnormal activation and injury of EC, and plays a central role in the regulation of dysfunctional changes in the disease process. The Ang/Tie signaling pathway mainly includes two tyrosine kinase receptors (Tie1, Tie2) located in EC and four secreted glycoprotein ligands (Ang-1, Ang-2, Ang-3, Ang-4). Ang-1 sustainably activates the Tie2 receptor, maintaining function between cells, and between cell and matrix, supporting the normal physiological functions of vascular EC. Ang-2 is an Ang-1 antagonist, competitively blocking the binding of Ang-1 to the Tie2 receptor. In a sepsis environment, the ratio of Ang-1/Ang-2 decreases （Ang-1 decreases, while Ang-2 increases). Ang-2 competitively blocks the binding of Ang-1 to Tie2 receptors, resulting in severe abnormal activation of EC. Ang-2 mediates the release of heparinase (HPSE), resulting in glycocalyx damage and an increase of vascular permeability. Ang-2 increase may promote inflammatory response. Ang/Tie signaling system dysfunction results in coagulation dysfunction, and Ang-2 elevation is a sentinel event in disseminated intravascular coagulation. In terms of disease monitoring, the sensitivity of Ang-2>5.61 ng/mL for diagnosing sepsis is 74.36%. Continuing rise of Ang-2 indicates that patients are in difficulty with restoring endothelial function and normal function in organs. Early dynamic mornitoring of Ang-2 can be used to predict sepsis related lung injury and acute kidney injury. The increase in Ang-2/Ang-1 ratio and Ang-2/soluble Tie ratio are independently correlated with the 90 d- mortality rate of sepsis patients（area under ROC curve is 0.787 and 0.704, respectively）. Decrease of Ang-2 and / or Tie-2 in levels indicates good efficay of plasma exchange in sepsis patients. Targeting the Ang/Tie signaling pathway have achieved certain success in animal experiments, but currently clinical trials have not yielded valuable results. Further in-depth research is needed on the Ang/Tie signaling pathway related to sepsis.

With the increasing number of users express their emotions via images on social media, image emotion analysis attracts much attention of researchers. For the ambiguity and subjectivity of emotion, image emotion analysis is more challenging than other computer vision tasks. Previous methods merely learn a direct mapping between image feature and emotion. However, in emotion perception theory of psychology, it is demonstrated that human beings perceive emotion in a stepwise way. Therefore, we propose a novel image emotion analysis framework that makes use of emotional concepts as middle-level feature to bridge image and emotion. Firstly, the relationship between the concept and the emotion is organized in the form of knowledge graph. The relation between the image and the emotion in the semantic embedding space is explored where the knowledge is encoded into. On the other hand, a multi-level deep metric learning method to optimize the model from both label level and instance level is proposed. Extensive experimental results on two image emotion datasets, demonstrate that the present approach performs favorably against the state-of-the-art methods on both affective image retrieval and classification tasks.

The three-dimensional network structure, which is formed by the precipitated wax crystals, is generally considered as the direct cause for gelling of waxy crude oil. Through interaction with wax molecules, the two polar components, namely the resin and asphaltene,participate in the wax crystallization and subsequently alter the wax precipitation properties. This makes it rather complicated to explore the gelling behavior of crude oil. The micro-dynamic behaviors among resin, asphaltene and wax molecules have a direct bearing on the morphology of mesoscopic wax crystals, and then play a decisive role in the macro-rheological property of waxy crude oil multiphase system. Macroscopically, the effect of resin and asphaltene on the rheology of waxy crude oil and its characterization methods were summarized based on the rheological experiments. Mesoscopically, microscopic experiments and molecular simulation were adopted to analyze the effect of resin and asphaltene on the morphology and particle size of wax crystal, as well as the synergistic mechanism among resin, asphaltene and wax crystals. Microscopically, the molecular coalescence and interphase interaction were introduced through the molecular dynamics simulation. Meanwhile, the effect of resin and asphaltene molecules on the gelling properties of waxy crude oil was discussed. Additionally, prospect was made to the application of molecular dynamics simulation in the field of waxy crude oil gelling, which is expected to lay a theoretical foundation for the development of waxy oil pipeline transportation technology and provide reference to the research, development and application of pour point depressant.

Objective To explore the efficacy and safety of TERVO stent in the treatment of acute ischemic stroke caused by brachial artery disease. Methods This retrospective study included 9 patients from March 2017 to September 2019 who suffered with acute ischemic stroke caused by brachial artery disease. Among them 5 cases suffered with middle cerebral artery (MCA) M2 occlusion, 2 cases with MCA M3 occlusion and 2 cases with posterior cerebral artery (PCA) P1 occlusion. All patients underwent thrombectomy by TREVO stent while 5 of them were also treated with intravenous thrombolysis in the Department of Vascular Intervention of Civil Aviation General Hospital. The vascular recanalization rate and postoperative bleeding rate were observed, meanwhile the National Institutes of Health Stroke Scale (NIHSS) was used before and 14 d after thrombectomy to assess the degree of neurological impairment. And the prognosis was assessed by the modified Rankin Scale (mRS) 90 d after the operation. Results Among the 9 patients, 8 cases successfully completed the operation of thrombectomy, with a success rate of 8/9. mTICI grading immediately after thrombectomy, showed that 6 patients had grade level 3, 2 had level 2b and one had level 2a, while the rate of vascular recanalization was 8/9. Intracranial hemorrhage occurred in one case, massive cerebral infarction in one case and the clinical symptoms of the other 7 patients were significantly improved after treatment. NIHSS score at admission of 9 patients was 9.00 (7.50, 11.00) while who scored 4.00 (2.50, 5.50) 14 d after thrombectomy. mRS ≤ 2 in 7 cases and > 2 in 2 cases were followed up in 90 d after thrombectomy, with a good prognosis in 7/9. Conclusions TREVO stent has favorable efficacy and safety in the treatment of acute ischemic stroke caused by brachial artery disease. [ABSTRACT FROM AUTHOR]

Objective To investigate the effects of sterol regulatory element binding protein 1c (SREBP1c) deficiency on the intestinal microbiota in mice. Methods SREBP1c knockout (SREBP1c-KO) mice were used as research objects, and the feces of homozygous SREBP1c-KO mice and wild-type littermates (WT) were collected. Subsequently, the fecal genomic DNA was analyzed by 16S rDNA sequencing. The differences of gut microbial composition between the SREBP1c-KO and WT mice were detected and compared using species taxonomy analysis, diversity index analysis, cluster analysis, and principal component analysis (PCA). Moreover, the discrepancies of liver lipid anabolism and intestinal barrier were also investigated between the 2 groups. Results Under conventional feeding, SREBP1c knockout had no significant effect on the body weight and total cholesterol (TC) content in the liver of mice, but notably decreased the content of triglyceride (TG) in the liver. α diversity index (Sobs index) analysis showed that the gut microbiota diversity of SREBP1c-KO mice was greatly lower than that of the WT counterparts (P < 0.01), and PCA analysis indicated that the gut microbial composition was different between the 2 groups of mice. At the phylum level, the ratio of Firmicutes to Bacteroides presented an upward trend in the intestine of SREBP1c-KO mice, but there was no statistical difference. At the genus level, as compared with the WT group, the relative abundance of Rikenella was significantly reduced in SREBP1c-KO mice (P < 0.05). Additionally, the expression levels of intestinal barrier associated genes Reg3γ and Occludin were obviously down-regulated in SREBP1c-KO mice. Conclusion The deletion of SREBP1c, an important regulator of lipid metabolism, reduces the diversity of intestinal microbiota and the relative abundance of Rikenella in mice, which may be related to the weakening of intestinal barrier.

The new power system with high proportion of new energy and power electronic equipment is an important means to achieve the goal of “double carbon”, but the new power system will also bring a series of unstable problems. In the new power system, grid-forming control technology (GFM) has the characteristics of voltage support and active inertia, which can replace synchronous machine to realize grid support and maintain power system stability. Therefore, GFM has a broad development and application prospect. Based on this, this paper first briefly introduced the topology of energy storage converter, and selected its type according to the control characteristics of GFM technology. After that, a reasonable summary and analysis of the existing control strategies of GFM was made, the current research difficulties, problems and challenges in the development process and the research prospects were put forward, and the ideas for the construction of grid-forming construction were provided.

This article gives a review on the application status and clinical effect of behavioral activation （BA） therapy for patients with late-life depression， in which the theoretical content， research status and the characteristics of clinical application of BA therapy for patients with late-life depression were introduced， and the existing limitations and possible directions for future research were summarized， so as to provide references for the localization of BA therapy for patients with late-life depression.

Using Design Builder energy and carbon emissions analysis software, based on the typical residential building information in Jilin Province,the simulation model of energy consumption and carbon emissions of residential buildings in severe cold regions was constructed. A representative heating mode was proposed to analyze the energy consumption and carbon dioxide emissions of residential buildings under traditional and new heating modes. The study found that during the entire heating period in the severe cold region, the intermittent central heating mode reduced the carbon dioxide emissions by 12.01% compared with the all-day heating mode,and the emission reduction effect was significant;The mode is more suitable for residential buildings in severe cold regions. Especially in January,the intermittent central heating mode was more than full-day. The carbon dioxide emissions in heating mode are reduced by 1867.7 kg. [ABSTRACT FROM AUTHOR]

In order to evaluate the influence of the thickness of the stent on the fatigue strength after implantation of the blood vessel, we established a two-way fluid-solid coupling model of the blood vessel、stent and the blood in this paper. The ANSYS finite analysis software was used in this paper to simulative analysis the fatigue performance of stent after implantation, the coupling calculation of structural solid mechanics analysis and fluid dynamics analysis is realized, and the numerical results of the stent under a blood pulsating load are obtained. According to the simulation results, the fatigue performance of the implanted stent is evaluated by Goodman criterion and dynamic safety factor. The results show that the multi-component nature of blood has a greater impact on the stress fluctuation of the stent; the thickness of the stent has almost no effect on the stress distribution of the stent, but has a greater impact on the fatigue performance.

The purpose of this study was to retrospectively investigate the prognostic significance of the lymphocyte-to-monocyte ratio (LMR) in patients with middle and advanced thoracic malignant tumors (esophageal and lung cancer) prior to and after radiotherapy. The clinical data of 74 patients with middle-advanced stage lung and esophageal cancer who received radiotherapy in Jiangsu Shengze hospital from January 2017 to December 2021 were screened for this retrospective analysis. Peripheral blood was collected, and LMR was recorded before and within one week following radiotherapy. The receiver operating characteristic curve (ROC) was established to obtain the best cut-off value for overall survival (OS). The correlation between LMR and prognosis before and after radiotherapy was examined. The Kaplan-Meier method was used to create the survival curve, and Cox proportional hazard regression model was used for univariate and multivariate analysis. The median follow-up time was 15 months, and the median age was 70 years. According to the ROC curve, the best critical value of LMR prior to radiotherapy was 2.46, AUC=0.719, while the best critical value of LMR after radiotherapy was 1.07, AUC=0.682. The Cox risk ratio model showed that clinical stage, diagnosis, combination therapy, and LMR before and after radiotherapy were all related to prognosis. Multivariate analysis revealed that clinical stage, combination therapy, and LMR before and after radiotherapy were independent prognostic factors in patients with middle and advanced lung and esophageal cancer following radiotherapy (p

This paper reviewed the clinical data of a typical elderly paranoid schizophrenia (SP) patient, and experience of narrative nursing combined with nostalgia therapy was summarized. The multi-disciplinary team (MDT) made an assessment and diagnosis at the patient first, and then according to evidence-based search to develop intervention plans, which included drug therapy, physical therapy and rehabilitation and nursing intervention. Specifically, the nursing intervention was mainly about narrative nursing combined with nostalgia therapy. After the intervention, the patient's mental symptoms were effectively controlled, sleep quality and medication compliance were improved. The implementation of narrative nursing combined with nostalgia therapy is potentially effective to improve the mental rehabilitation the SP patient (本文回顾1例典型老年期偏执型精神分裂症(SP)患者的临床资料, 总结叙事护理联合怀旧疗法护理干预措施。通过多学科团队(MDT)评估、诊断, 再根据循证检索制定干预计划, 包括药物治疗, 物理治疗与康复, 护理干预等。老年科特色护理干预包括叙事护理、怀旧疗法和引导式认知训练等。经干预后患者精神症状得到有效控制, 睡眠质量和服药依从性得到改善。叙事护理联合怀旧疗法能够有效促进老年SP患者康复。)

Aiming at the problems of structural dimension deviation, initial cracks and apparent defects in beam-column and other structures that occurred during the construction by Pile-Beam-Arch(PBA)approach, Based on the stochastic medium theory, a theoretical analysis model of the space-time effect of group tunnels excavation is established. The causes for the deviation of the building arches caused by the asymmetric construction are analyzed. Taking asymmetric excavation of 8 pilot tunnels in a typical PBA station as an example, the mechanism of uneven changes in stratum space caused by multi-step construction of pilot tunnels in large-span cross-section tunnels is researched. The essential cause of the deviation of the building arches is analyzed, and the deformation law of the surface settlement trough spatial shape swinging left and right with the excavation of the guide tunnel is reconstruced. According to the above research, it is pointed out that the arching being closed and looped, the rapid synchronization operation, the side hole divided into span building arches and construction optimization to achieve symmetric synchronization are the main countermeasures to eliminate or reduce the deviation of building arches.

Inductively coupled power transmission (ICPT) systems cause fluctuations in output power and output voltage when the coil is offset.The existing anti-misalignmemt methods have the problems of relying too much on the system modeling and poor adaptivity. Most of the methods do not consider the impact on the system output characteristics when the coupling coefficient changes continuously. To address the above problems, taking the dual-coupled LCL topology ICPT system based on DDQ coils as the research object, the paper proposes a strong anti-misalignmemt method based on fuzzy adaptive control in variable universe. Firstly, the output power expression of the dual-coupled LCL topology ICPT system is derived from the circuit analysis, and the relationship between the output power, the coupling coefficient and system parameters is obtained. Secondly, by applying the finite element analysis software ANSYS, a three-dimensional magnetic field modeling of the DDQ coil is carried out to obtain the correspondence between the coupling coefficient and the coil offset. On the basis, the corresponding values of the three sets of offsets and the coupling coefficients are used as the data, and the square sum of deviations of the system output power fluctuations is taken as the objective function. Hence, the parameter optimization method of ICPT system based on adaptive particle swarm is proposed to obtain a set of optimal parameter values of the system under the minimum output power fluctuation and improve the anti-misalignmemt performance of the system to a certain extent. Finally, a fuzzy adaptive control method based on variable universe is used to achieve the purpose of quickly adjusting the load terminal voltage by dynamically adjusting the correction value of the PID control coefficient to make the system output higher power. The simulation results show that the method solves the problem of poor adaptivity of existing methods, adapts well to the working conditions with continuous changes of coupling coefficients, has better adaptability and control effect, improves the strong anti-misalignmemt performance of ICPT system, and maintains the basic constant output voltage at the load side.

The application of self-assembled membrane technology in metal surface corrosion protection is more and more extensive. Using simple and effective membrane technology to prepare green and environment-friendly membrane products has become a research hotspot in the field of anti-corrosion membrane. In this paper,the research progress of metal surface self-assembled film preparation technology is summarized.Taking the metal surface self-assembled monolayer membrane and its composite membrane as the research object, the classification, characteristics, applications and anti-corrosion mechanism, etc.of self-assembled membrane technology on the surface of aluminum/aluminum alloy, copper, copper alloy, stainless steel and other active metals are expounded respectively.It is pointed out that the research on the interface bonding between membrane and substrate, mechanism of film formation, mechanism of corrosion protection and so on is not perfect yet, which is still a scientific problem to be solved urgently.

Objective To investigate FoxO3 expression in bladder cancer and its correlation with clinicopathological features and prognosis. Methods Bladder cancer and adjacent tissue specimens were collected from 111 patients with bladder cancer. FoxO3 expression was detected by RT-qPCR, immunohistochemistry and Western blot. The relationship between FoxO3 expression and clinicopathological features and prognosis of bladder cancer patients was investigated. Kaplan-Meier survival analysis was performed on FoxO3, and Cox proportional hazards model was used to analyze the independent prognostic factors for bladder cancer. Results The mRNA and protein expression of FoxO3 in bladder cancer tissues was down-regulated, compared with adjacent tissues (P < 0.05). The positive rate of FoxO3 protein in patients with lymph node metastasis was significantly lower than that in patients without lymph node metastasis (P < 0.05). The positive rate of FoxO3 protein was significantly lower in patients with Tis-T1 superficial bladder cancer than that in patients with T2-T3 invasive bladder cancer; and it was also decreased in the patients at middle and high histological classification, compared with those at low histological classification (P < 0.05). The positive rate of FoxO3 was positively correlated with deterioration of bladder cancer (P < 0.05). The negative expression of FoxO3 and lymph node metastasis were considered as the risk factors for poor prognosis of bladder cancer patients. Conclusion Low expression of FoxO3 is identified as an important regulator in bladder cancer. Negative FoxO3 expression is risk factor for poor prognosis of patients with bladder cancer.

Based on the energy flux and meteorological data during 2011-2012 over a sparse shrubland ecosystem in the farming-pastoral zone of the Loess Plateau, this study investigated the diurnal and seasonal variations of the energy balance components, and discussed the responses of the latent and sensible heat fluxes to different intensities of rainfall events. In addition, we identified the major environmental controlling factors on latent and sensible heat fluxes via correlation analysis. The results showed that the diurnal and seasonal variations of net radiation (Rn) , sensible heat flux (H), latent heat flux (LE) and soil heat flux (G) all showed single-peak curves. The annual mean values of Rn, H, LE and G were 78.19, 33.32, 24.91 and 2.65 W • m-2, respectively. The ratios of energy budget components to net radiation were 43% (H/Rn) , 32% (LE/Rn) , and 3% (G/Rn) , which indicated that sensible heat flux was the major form of energy loss at this site. In the growing season, the ratios of sensible heat flux and latent heat flux to net radiation were nearly the same ( 36%) ; while in the non-growing season, sensible heat flux accounted for 54% of net radiation. Latent heat flux increased sharply after heavy and weak rainfall events, while sensible heat flux decreased sharply at the same time. Continuous rainfall events would lead to fluctuations in latent and sensible heat fluxes. There were significant correlations between latent heat flux and net radiation, vapor pressure deficit and vegetation parameter, while remarkable correlations were found between sensible heat flux and net radiation, and air temperature gradient. [ABSTRACT FROM AUTHOR]

Self-similarity of network traffic has a great impact on network performance, and can lead to large queuing delays and packet loss rates. To avoid this problem, this paper proposed an active queue management algorithm considering the selfsimilarity of traffic. The proposed algorithm estimated based on the wavelet method, and simultaneously analyzed the self-similar process and determined the degree of the self-similarity using the estimation results. Then it classified the network traffic based on the real-time estimation of Hurst parameter. In the simulation, it generated the network configuration by MATLAB, and simulated the network traffic by Pareto distribution. The performance of the proposed algorithm was compared with that of other buffer management algorithm, and the simulation results verify that the proposed algorithm has better fairness, and show that under congested circumstances, the proposed algorithm can avoid the influence of dropped packets on other queues. [ABSTRACT FROM AUTHOR]

For cluster nodes in wireless sensor networks energy load imbalance to cause cluster head to early death in the case of more tasks, and routing problem such as larger energy loss, this paper proposed an adaptive energy optimization clustering routing algorithm. Fully considering the node residual energy and distance by the weigh coefficient on the cluster head election and competition radius calculation, which achieved prolong the life cycle of the cluster head. For-warding data between the provisions of the cluster head is to use more than one hop routing or hop routing by the form of the routing rules, to maximize reduce the energy loss in the routing in the case of cluster does not guarantee the early death. [ABSTRACT FROM AUTHOR]

In order to guarantee the normal operation of the electric locomotives, it is necessary to detect the dynamic pantograph-catenary geometry parameters, such as the contact line height and the pull-out value in real time. At first, after analyzing the imaging features of the pantograph and the contact line, the pantograph is extracted combining the level lines detection and the template matching, and the contact line is extracted using a simple locating and tracking method. Then the contact line height and the pull-out value are calculated after camera calibration. Finally the system will compare the results with the vigilance parameters and if there exists abnormal information, the system will make alarm by message and upload the abnormal information to the database. The practice result shows that the system can detect the contact line height and the pull-out value exactly, and is not sensitive to the variety of light and the complex background, so it fully meets the need of the detection in industry. [ABSTRACT FROM AUTHOR]

Objective The aimwas to investigate the correlation of Bmi-1 gene expression with the malignant behavior of different types of epithelial ovarian cancer. Methods Immunohistochemical stains SABC method was used to detect the expression of Bmi-1 in epithelial ovarian cancer tissues, including 10 cases of serous adenocarcinoma, 8 cases of mucinous adenocarcinoma, 6 cases of endometrioid carcinoma, 28 cases of benign ovarian tumor and 30 cases of normal ovarian tissue. And the relationship of the expression with age of patients, histological type and clinical stage were statistically analyzed. Results (1) The positive rate of Bmi-1 gene in serous adenocarcinoma, mucinous adenocarcinoma and endometrioid carcinoma was 60.00%, 62.50% and 50.00%, respectively. All rates were significantly higher than those in benign epithelial ovarian tumor (7.14%) and normal ovarian tissue (6.67%), with statistical significance (P<0.05), but there was no statistical difference among the ovarian epithelial carcinoma histological groups (P > 0.05). (2) In 24 cases of epithelial ovarian cancer, the positive expression rate of Bmi-1 (100%) in the tissue of stage III patients was significantly higher than that in the cancer tissue of stage I-II (41.48%). And the expression was enhanced with the increased clinical stage of International Federation of Gynecology and Obstetrics (FIGO 2000), with statistical significance (P < 0.05), but the expression of Bmi-1 was no difference in the age of epithelial ovarian cancer patients (P > 0.05). Conclusion Bmi-1 gene plays an important role in the occurrence, development and progress of epithelial ovarian cancer. [ABSTRACT FROM AUTHOR]

Taking into consideration the disadvantages of the serial structure controller-slow operation speed, poor grid current quality for the present grid-connected invert, the authors proposed a new grid-connected invert architecture, which is based on SOPC control technology on FPGA platform. It adopts the direct current PI control strategy with grid voltage feed-forward and uses hardware to realize algorithm, which improved the running speed and the overall performance of system. Meanwhile, designed regulator parameters for the control strategy and constructed grid-connected control system IP hard core for the invert in this paper. Experimental results of 1 kW prototype show that this method has good grid current quality and strong synchronous tracking capability.

With a new round of gas pipeline project construction such as"Burma-China pipeline", "the second and third line of West-East natural gas transmission project" and "liquefied natural gas ashore", the flow meters for measuring gas flow are increasing. The only way to ensure these meters work accurately is to calibrate these meters precisely, which will make it more equitable for the transfer of natural gas trade. In this paper, basing on three levels of gas flow meter verification station, considering the influence of the increase of kinetic energy along the pipeline's on flow, the pressure loss model is established when natural gas flows in the verified pipe, and the parameters variation in different caliber meters calibration by MATLAB software are calculated, then the pressure difference is solved and the uncertainty in certification process is calculated, which conforms to the natural gas dispatching request. [ABSTRACT FROM AUTHOR]