Search

Copyright of Journal of Prevention & Treatment For Stomatological Diseases is the property of Journal of Prevention & Treatment For Stomatological Diseases Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Remote Sensing is the property of Editorial Office of Journal of Remote Sensing & Science Publishing Co. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Cancer Biotherapy is the property of Editorial Office of Chinese Journal of Cancer Biotherapy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: The evaluation and management of cervical vascular pathologies before orthopedic manual therapy have great significance for reducing risks, ensuring patients’ interests and promoting optimal clinical decision-making. However, the research and exploration of this field in China are still in its infancy. In 2020, the International Federation of Orthopaedic Manipulative Physical Therapists (IFOMPT) released the International Framework for Examination of the Cervical Region for potential of vascular pathologies of the neck prior to Orthopaedic Manual Therapy (OMT) Intervention: International IFOMPT Cervical Framework (2020). This framework has important references and guiding values for the clinical practice of cervical manipulation in China. OBJECTIVE: To integrate and interpret the core content of the framework, to provide a reference for the clinical practice of cervical manual therapy in China. METHODS: On the basis of a full study of the framework, the authors interpret the core content of the framework from eight aspects including clinical reasoning, patient history, planning the physical examination, physical examination, risk and benefit. Meanwhile, seven databases including PubMed, EMbase, Cochrane Library, CNKI, WanFang, VIP and China Biomedical Literature Service System databases were searched by computer to screen clinical practice guidelines and expert consensus on neck pain. Through longitudinal comparison of multiple high-quality guidelines and consensus, the authors combine with the clinical practice in China to carry out discussion and analysis. RESULTS AND CONCLUSION: This framework expounds the management strategy and implementation path of cervical vascular disease evaluation before cervical manipulation from multiple dimensions, suggesting that we should improve clinicians’ attention to cervical vascular disease evaluation before manipulation, and construct evaluation criteria and implementation path with Chinese clinical characteristics. Meanwhile, we should further carry out basic scientific research with multidisciplinary techniques and promote shared decision-making and teaching model innovation to achieve the best clinical decision. [ABSTRACT FROM AUTHOR]

Objective: To investigate the active components, protein targets, and mechanisms underlying the anti-obesity effects of Hippophae fructus using network pharmacology and molecular docking techniques, and to validate its in vitro anti-obesity efficacy. Methods: The TCMSP platform was utilized to retrieve the active components and targets of Hippophae fructus, and disease targets were collected. Venny 2.0.2 was used to identify the intersection of targets between Hippophae fructus and obesity-related targets. The STRING database was used to establish a drug-target-disease protein interaction (PPI) network. The intersecting targets were analyzed using the David database to perform GO enrichment analysis and KEGG pathway analysis. Cytoscape 3.9.1 was used to construct a network diagram of the components of Hippophae fructus, anti-obesity targets, and related signaling pathways. Autodock Dock 1.5.7 and Pymol 2.2.0 were used to carry out molecular docking between the core targets of Hippophae fructus and its components, followed by visualization. The in vitro anti-obesity effect of Hippophae fructus extract was evaluated through cell experiments using 3T3-L1 cells. Results: A total of 33 active components, 2820 disease targets, and 151 intersection targets of Hippophae fructus were identified. The main active components included flavonoids, vitamins, and sterols, while key targets involved AKT1, TNF, IL6, TP53, VEGFA, CASP3, and others. KEGG pathway enrichment analysis revealed 131 signaling pathways, including those related to malignant tumors, lipid and atherosclerosis, and AGE-RAGE signaling. Molecular docking results demonstrated favorable binding interactions between the core targets and the corresponding active components of Hippophae fructus. The in vitro experiments indicated that Hippophae fructus extract exhibited inhibitory effects on the proliferation of 3T3-L1 pre-adipocytes. Conclusion: This study reveals that Hippophae fructus exerts antiobesity effects through multiple components, targets, and pathways, providing valuable insights for its clinical research and product development. [ABSTRACT FROM AUTHOR]

Background and purpose: Follow-up data of 6 737 patients undergoing surgery for gastric cancer were collected based on hospital registration, and the 1-, 3- and 5-years observed overall survival (OS) rates and disease-free survival (DFS) rates were analyzed to provide real-world research evidence for the prevention and control of gastric cancer and policy making in China. Methods: A total of 6 737 gastric cancer patients who underwent surgical treatment at Fudan University Shanghai Cancer center from 2015 to 2020 were included in this study. Clinical information and the follow-up endpoint data were collected through medical records review, telephone visits and death registry data linkage. The last follow-up date was November 30, 2023. Kaplan-Meier method was applied in evaluating the 1-, 3- and 5-year OS rate and DFS rate, and survival data were described by different subgroups including age group, gender, treatment period, tumor staging, and pathological characteristics. Results: With a median follow-up time of 50.99 months, the 5-year OS rate of surgically resected gastric cancer patients was 70.37%, and 5-year DFS rate in I-III stage cases was 69.46%. The 5-year OS rates of stage I, II, III and IV were 94.32%, 82.56%, 51.01% and 23.97%, respectively. The differences in survival among patients with different age, tumor location, gross classification, Borrmann classification and Lauren classification were significant. Conclusion: Staging is an important factor directly affecting the survival of gastric cancer patients. Screening and early diagnosis and treatment in large population, especially high-risk group, should be strengthened to further improve the patients' survival. [ABSTRACT FROM AUTHOR]

Objective To investigate the relationship between frailty and social activity of the elderly in China, and to study the influencing factors of frailty in the elderly, so as to provide scientific basis for the healthy life of the elderly. Methods Based on 43 health related variables in China Health and Retirement Longitudinal Study (CHARLS) 2018 database, the frailty index (FI) was constructed to evaluate the frailty of the elderly. Binary logistic regression was used to explore the effect of social activity on the frailty of the elderly. Results A total of 1 519 elderly people aged 60 and above were included in the CHARLS 2018 database, including 401 frail elderly, with a frailty rate of 26.4%. The participation rate of the elderly in social activities was 48.5%, and there were 439 elderly people with high level of social activity, accounting for 28.9% of the total. After adjusting for confounding factors, the risk of debilitation in the elderly with high level of social activity was 41.9%, lower than that in those with medium and low level of social activity (0fl=0.581, 95%CH: 0.439-0.77). Conclusion The degree of social activity affects the frailty of the elderly, and the social activity of the elderly in China is generally low. The elderly should be encouraged to participate in social activities, and attention should be paid to the older and female elderly. [ABSTRACT FROM AUTHOR]

The study was based on network pharmacology and molecular docking techniques, and investigated the active components and mechanisms through which Atractylodes macrocephala regulates oxidative stress. Active components and target proteins of Atractylodes macrocephala were screened from the TCMSP database, while oxidative stress-related targets were obtained from GeneCards and OMIM databases. Using STRING 11.5 platform and Cytoscape 3.7.2 software, a network of Atractylodes macrocephala-components-targets and a PPI network were constructed, and core targets were identified. The DAVID database was utilized for GO and KEGG pathway enrichment analysis. Molecular docking using AutoDockTools software examined the binding efficacy of active components with core targets. The results showed six main active components, including 12-kirenol acyl-8-epi-heliangolide, 14-acetyl-12-kirenol acyl-8-epi-heliangolide, α-amyrin, β-sitosterol, 3β-acetoxyatractylone, and 8β-ethoxyhirsutinolide, along with 133 key targets. GO functional enrichment yielded 460 terms, and KEGG pathway annotation identified 127 signaling pathways, including TNF, AGERAGE, IL-17, and PI3K-Akt pathways. Molecular docking results demonstrated favorable binding activity between Atractylodes macrocephala active components and core targets, with α-amyrin showing the highest binding ALB, EGFR, MAPK1, NQO1, and PTGS2. The study indicates that Atractylodes macrocephala may exert its antioxidant effects by regulating signaling pathways such as TNF, AGE-RAGE, IL-17, PI3K-Akt, and oxidative stress-related targets. [ABSTRACT FROM AUTHOR]

The signal systems under the traditional architecture have a high degree of independence and cannot achieve information fusion among multiple systems. In order to realize information sharing with the urban rail production network and enable big data mining, the signal ATS subsystem can be included in the urban rail cloud platform. On the basis of ensuring the independence and safety of the core equipment of the signal systems, the ATS subsystem center-level servers and workstations are included in the cloud platform. This paper calculates the computing resource requirements of the ATS subsystem with a reuse ratio of 1.0 as an example. The connection between the cloud part and the non-cloud part of ATS is realized through the core switching network of the cloud platform. The application server and interface server are configured with blade servers, and the database server is configured with a rack server. To meet the requirements of ATS subsystem redundancy and undisturbed switching, the cloud platform provides two sets of server resources with the same configuration for the ATS subsystem. Considering that the urban rail signal systems need to meet the requirements of Level 3 of Information Security Level Protection, the cloud platform should also be built according to Level 3. [ABSTRACT FROM AUTHOR]

We analyzed the changes in the number of publications, the status of authorship and institutional cooperation, and the evolution of research themes in the field of electrostatic spinning in China based on CNKI database using CiteSpace visual metrics, and compared with the international research themes in the years from 2018 to 2022. The volume of domestic authors' publications in the field of electrostatic spinning showed a trend of increasing year by year; the local density of author co-occurrence network was large, and the overall density was small; there was close cooperation between universities involved in electrostatic spinning research. The research in electrospinning field in China is mainly focused on the preparation of fibers and the application of nanofibers in the fields of biomedicine, air filtration, water treatment, energy devices, protection, sensing, etc., which is similar to the international research hotspot of electrostatic spinning. [ABSTRACT FROM AUTHOR]

BACKGROUND: Cryopreservation can better ensure the integrity of the vascular structure. How to reduce its immunogenicity to improve rejection after transplantation has attracted more and more attention. OBJECTIVE: To review the research progress of freezing treatment to reduce vascular immunogenicity after allogeneic vascular transplantation in order to provide a reference for clinical research. METHODS: A systematic search of Chinese and English databases CNKI, WanFang and PubMed, as well as online websites Baidu and Google Scholar since the establishment of the database has published literature on reducing vascular immunogenicity after allogeneic vascular transplantation. Keywords were “cardiovascular disease, endothelial cells, cryopreservation, blood vessel transplantation or vascular graft, immunogenicity, immune rejection, allograft or allogeneic transplantation or allograft transplantation and cryoprotectant”. A total of 68 articles were included according to the inclusion and exclusion criteria. RESULTS AND CONCLUSION: (1) The review found that the rejection of allogeneic vascular transplantation can be reduced by improving the existing freezing technology, which mainly involves the selection of freezing and thawing methods and cryoprotectants. (2) The existing research suggests that the freeze-drying method is superior to the low-temperature cryopreservation, but due to the limited conditions, it is still dominated by low-temperature cryopreservation. Among them, vitrification cryopreservation, slow rewarming and the use of stainless steel and even silver-containing materials are better than programmed cryopreservation and rapid rewarming. (3) The combined selection of permeable and non-permeable cryoprotectants can further reduce the occurrence of rejection while reducing their toxicity. [ABSTRACT FROM AUTHOR]

Objective: To analyze the differentially expressed genes (DEGs) and immune cell infiltration patterns in hypertensive nephropathy (HN). Methods: Downloaded gene chip dataset of HN and healthy human renal tubulointerstitial tissue samples from GEO database, and used R software to analyze DEGs. Metascape online analysis platform was used to analyze functional enrichment of DEGs. Three machine learning algorithms, LASSO, SVM-RFE and RF, were used to screen feature genes and verify the diagnostic value. Finally, CIBERSORT algorithm was used to analyze immune cell infiltration. Results: Total 277 DEGs were obtained. Functional enrichment analysis showed that they were related to many immune-related processes, such as innate immune response, humoral immune response and response to cytokines. Three characteristic genes, CISH, GADD45A and ZFP36, were obtained by machine learning algorithm, which had good diagnostic value. Immune cell infiltration analysis showed that Tregs and macrophages M1 infiltrated more. And there was a correlation among many kinds of immune cells. Conclusion: Pathogenesis of HN may be related to a variety of immune-related processes, Tregs and macrophages M1 may play a key role in pathogenesis of HN. CISH, GADD45A and ZFP36 are potential diagnostic markers of HN. [ABSTRACT FROM AUTHOR]

Objective To analyze the development status and research trend of premature ejaculation treatment. Methods By systematically searching the Web of Science (WoS) core collection database, the related literatures to premature ejaculation treatment were obtained from January 1, 2000 to December 31, 2020. The distribution characteristics, research hotspots, and research frontiers of global research literatures on premature ejaculation treatment were visually analyzed using CiteSpace software. Results A total of 2 433 articles were included, and 10 keyword clustering labels were formed. Research hotspots mainly focused on the epidemiological characteristics and treatment of premature ejaculation, and research trends on systematic evaluation of diseases and nursing care. Conclusion The treatment of premature ejaculation has received increasing attention in the last two decades. In the future, we will strengthen international exchanges to promote research on premature ejaculation treatment in China relying on the cultural background of the Chinese medical field. [ABSTRACT FROM AUTHOR]

Objective To explore medication rules of traditional Chinese medicine in the treatment of teratozoospermia based on clinical literature data mining for providing guidance methods for teratozoospermia treatment. Methods Clinical literatures on teratozoospermia treatment with traditional Chinese medicine from database establishment to December 31,2022 were retrieved and collected from the database of CNKI, Wanfang and VIP. SPSS and Excel were used for data mining to summarize the clinical medication rules of teratozoospermia. Results A total of 101 related literatures were initially retrieved, and 57 clinical literatures were ultimately obtained, including 64 prescriptions containing 145 kinds of traditional Chinese medicine. Eight syndrome elements were extracted, mainly including essence deficiency, blood stasis, damp-heat and yin deficiency. The disease mainly located in kidney, spleen and liver. Cuscuta chinensis and Lycium barbarum were the most common clinical drugs, and the main drugs were tonic drugs. The property of the drug was warm and mild, the taste of the drug was mainly sweet, and the meridian tropism was mainly in the kidney, liver and spleen. Association rule analysis showed that there were 8 pairs of combinations with high correlation strength, and the results of hierarchical cluster analysis revealed 3 categories. The network visualization of association rules indicated that the core drugs included 16 kinds such as dodder, wolfberry fruit, cornus officinalis, prepared rehmannia root, etc., and the compatibility correlation between drugs was high. Conclusion The basic pathogenesis of teratozoospermia is essence deficiency and kidney deficiency, damp-heat descending and blood stasis blocking collaterals. The main treatment is to tonify deficiency, clear heat, remove dampness and activate blood circulation. [ABSTRACT FROM AUTHOR]

Copyright of School Administrators is the property of School Administration Research Association, R.O.C. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The city block search engine is a type of urban cognitive intelligence. By extracting various sources of city data and establishing a city block retrieval model, it can simplify the cognition of urban design in the early stage. This study introduces ArchIndex, featuring a dynamic web-based city block search engine. Based on a regularly updated spatial relation database, it collects city data and builds indicators of form, function and activity for retrieval and visualization of morphology. The study can establish indexes for any city through distributed cloud computing. Via its web application, it supplies user-friendly tools and pioneering methods conducive to urban morphology research. [ABSTRACT FROM AUTHOR]

To investigate the common characteristics of mammalian virus co-receptors, this study collected 277 pairs of viral co-receptor combinations based on the data from ViralReceptor database. We investigated the structural, functional, evolutionary and tissue expression characteristics of mammalian virus co-receptors and compared them with combinations of viral receptors derived from different mammalian viruses, as well as randomly selected human proteins. The results showed that in comparison to other protein pairs, mammalian virus co-receptors exhibited higher functional similarity, higher ratio of interaction in the host protein interaction network, and higher co-expression levels in common human tissues. This study demonstrates that mammalian virus co-receptors share common features such as functionality, expression, and interaction, with the expectation that these findings will provide a reference for the discovery and identification of virus receptors. [ABSTRACT FROM AUTHOR]

Indexing is an important method to improve database performance. At present, with the development of reinforcement learning algorithm, there are a series of methods to solve the index recommendation problem（ISP） by reinforcement learning. Aiming at the problem that the existing deep reinforcement learning index recommendation algorithm has long training time and unstable training, this paper proposes an index recommendation algorithm based on A2C（Advantage Actor-Critical）, PRELIA（Parallel Compensation Learning Index Advisor）. In order to improve the accuracy and efficiency of index selection and reduce the occupation of index space, the algorithm adds the characteristic matrix of the number of rows scanned by load index and normalizes the reward value. Experimental results on different data sets show that the proposed algorithm can guarantee the index recommendation quality equivalent to that of the compared algorithm, while the recommended index occupies less storage space, and the training time is more than 4 times longer than that of the baseline algorithm. [ABSTRACT FROM AUTHOR]

Based on the 411 key research papers published in CNKI database from 1994 to 2021, the published works, research institutions and research strengths, journal sources, high frequency co-cited literature and classical literature contents in the field of margin trading in China were systematically analyzed. Employing the CiteSpace software to draw a knowledge map, the evolution process, research frontiers and trends of domestic margin trading research hotspots were summarized. The results show that the overall number of research papers and their cyclical fluctuation in the domestic margin trading field are subject to the expansion policies. Fudan University, Nanjing University, etc. as the main research institutions had made the biggest contributions; researches concerning the stock price volatility and pricing efficiency by Chu Jian, Li Zhisheng and other scholars had become high frequency cited results in this field. The research process in the field of margin trading were divided into five stages: germination, start, landing, development and maturity. The research hotspots were mainly concentrated on five aspects: market impacts relationship, corporate decision-making and management, stakeholder influence, R&D investment relationship and business theory improvement, which can provide a frame of reference for scholars studying margin trading business. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Education Research (1680-6360) is the property of Angle Publishing Co., Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to quantify the garment style and realize the digital construction of the garment style database, the dress was taken as an example to disassemble the various parts of the garment style and extract the effective influencing factors of the garment style, semantic difference method, triangular fuzzy number and analytic hierarchy process were used for modeling, and a comprehensive analysis was made by questionnaire survey and quantitative theory. The relationship between style quantification and style design elements was obtained, and the digital standard of style features was established, and 8 groups of style databases were finally formed ( elegant-unisex, formal-casual, exotic-futuristic, minimalism-mix-match style). The construction of style database provides a perfect data basis for the realization of intelligent clothing style recommendation. [ABSTRACT FROM AUTHOR]

BACKGROUND: miRNAs play an important role in the pathogenesis of osteoporosis, which therefore can be important therapeutic targets. Among them, targeting the miR-100-5p regulatory axis to promote osteoblast differentiation is a potential therapeutic target for osteoporosis. OBJECTIVE: To explore the targeted regulatory roles of has-miR-100-5p and has-miR-101-3p in postmenopausal osteoporosis. METHODS: Differentially expressed genes between high and low bone mineral density in the GSE56814 and GSE56815 datasets were identified and subjected to enrichment analyses. Target genes of has-miR-100-5p and has-miR-101-3p among the differentially expressed genes were predicted. Peripheral blood samples from 40 patients with postmenopausal osteoporosis and 40 healthy controls were selected and qRT-PCR experiments were performed to detect the differential expression of has-miR-100-5p and has-miR-101-3p as well as target genes. Dual luciferase reporter assay was used to measure the targeting effect of miRNAs to the 3'UTR of target genes. RESULTS AND CONCLUSION: A total of 81 common differentially expressed genes were identified between high and low bone mineral density, mainly significantly enriched in immunity, nuclear factor-κB compound, and tumor necrosis factor signaling pathway. Has-miR-100-5p and has-miR-101-3p were targeted to regulate zinc finger and BTB domain containing 7A (ZBTB7A) based on miRTargetbase database and miRTarget database predictions. Has-miR-100- 5p was up-regulated (P < 0.001) and has-miR-101-3p and ZBTB7A were down-regulated (P < 0.001) in postmenopausal osteoporosis patients compared with the healthy controls. The fluorescence activity of 293T cells was down-regulated after co-transfection of has-miR-100-5p with wild-type ZBTB7A-3’UTR. To conclude, has-miR-100-5p targeting ZBTB7A may be a potential target for postmenopausal osteoporosis. [ABSTRACT FROM AUTHOR]

BACKGROUND: Clarifying the exact relationship between specific physiological periods and postmenopausal low bone mineral density in women can be a key to predicting low bone mineral density in postmenopausal women and provide a reference value for preventing the occurrence of low bone mineral density. OBJECTIVE: To investigate the association between different special periods and postmenopausal low bone mineral density in women. METHODS: A total of 15 560 samples were collected from the NHANES database (published from 2017 to 2020), and 1 563 participants were screened out. Their bone mineral density values were acquired to calculate the T-score. Those with osteoporosis and osteopenia were enrolled in observation group, while those with normal bone mass acted as controls. Three linear regression models were established to evaluate the effects of age at menarche, age at menopause, gravidity and parity on postmenopausal low bone mineral density. Finally, the results of multivariate logistic regression analyses were used to verify the relationship among gravidity, parity and low bone mineral density. RESULTS AND CONCLUSION: The incidence of postmenopausal low bone mineral density was 1.62 times higher in participants aged > 13 years at menarche than those aged < 12 years at menarche. Relative to menopausal age under 45, the odds ratio value for postmenopausal low bone mineral density was 0.72 for those between 45-55 years of age at menopause and 0.51 for those over 55 years of age at menopause. Gravidity was negatively correlated with the T scores of the femur and greater trochanter but showed no correlation with the T score of the lumbar spine. Parity was not related to the T scores of the femur and lumbar spine but only negatively related to the T score of the greater trochanter. The later the age of menarche, the earlier the age of menopause, the more pregnancies, the greater the likelihood of postmenopausal lower bone mineral density. Gravidity has the most significant effect on the bone mineral density of the femur and greater trochanter. [ABSTRACT FROM AUTHOR]

BACKGROUND: Lumbar intervertebral disc herniation is a common clinical disease. Its incidence is increasing year by year, which seriously affects the quality of life of patients and brings huge economic losses to the families of patients and society. At present, it is considered that the destruction of the integrity of intervertebral disc fibrous annulus is an important factor affecting the occurrence and development of lumbar disc herniation. Therefore, it is of great significance to restore the integrity of the annulus fibrosus for the treatment and prevention of lumbar disc herniation. OBJECTIVE: To review the research advance in intervertebral disc annulus repair in recent years. METHODS: PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and WanFang databases were searched systematically, with the key words “intervertebral disc, annulus fibrosus, repair, regeneration” in Chinese and English. Relevant articles published in each database in the last five years were collected. RESULTS AND CONCLUSION: In recent years, some progress has been made in the repair and regeneration of annulus fibrosus in and outside China. Although traditional physical repair has some shortcomings, it is still the main way of clinical treatment, while the application of tissue engineering in annulus fibrosus repair is only in the experimental stage and has not been widely used in clinical practice. There are many ways to repair intervertebral disc annulus fibrous, but the best way needs extensive animal and clinical trials to verify its safety and efficacy. The study on tissue engineering of annulus fibrosus repair has broad clinical application prospects. [ABSTRACT FROM AUTHOR]

Objective To comprehensively assess the correlation between obstructive sleep apnea ( OSA) and the incidence of erectile dysfunction(ED). Method The pertinent literature regarding the association between OSA and ED was systematically retrieved from databases including Scopus, Cochrane Library, PubMed, Ovid MEDLINE, Wanfang, and CNKI. The search timeframe encompassed the period from database inception up until December 19, 2022. Following thorough literature screening, data extraction, and bias risk evaluation conducted by two researchers, a meta-analysis was conducted. Results A total of nineteen articles comprising 116 419 cases were included in the analysis. The results of the meta-analysis demonstrated a statistically significant association between OSA and an increased risk of ED, with individuals suffering from OSA being 2. 52 times more likely to develop ED compared to those without OSA [ OR = 2. 52, 95% CI ( 1. 69, 3.75), P <0. 001]. Notably, Subgroup analysis indicated a significant association between OSA and ED in the European, small sample size, non-polysomnographic OSA evaluation tool, and database origin subgroups. [ABSTRACT FROM AUTHOR]

To further study the active peptide molecules in oats that may exert a hypoglycemic function it was first investigated the oat peptides extracted and identified from the literature, constructed the cor responding oat peptide database, and screened the peptide database based on DPP4 proteins. Subse quently, 100 ns of molecular dynamics simulations were performed for each of the six peptides obtainei through the screening. The interaction information between different peptide molecules and DPP4 wa analyzed from the stable binding conformations after simulation, and the binding free energy of differen peptide molecules and DPP4 was calculated respectively. The results show that the peptide molecule obtained from the virtual screening can all stably bind to the DPP4 protein, and two of the peptide mole cules have relatively strong affinity for DPP4. The peptide molecules obtained here can serve as leai molecules for the subsequent design and modification of DPP4 inhibitors, and the oat peptide databas can also be used to study other biological functions of oat. [ABSTRACT FROM AUTHOR]

In order to promote the application of biological breeding technology in agriculture and understand the development status, cultivation, import and export, and industrialization of global genetically modified (GM) oilseed rape crop, the analysis of global GM oilseed rape patent information through the Intelligent Bud Database (PatSnap) showed the global GM oilseed rape development trend, key technology areas, key acceptance countries, recearch and development (R&D) capability of each country, technology of R&D institutions in each country, competitiveness of major applicant institutions, legal status of patents, etc. The outlook and suggestions were proposed on GM oilseed rape R&D, layout of agricultural fields, global competition and promotion of oilseed rape industrialization. [ABSTRACT FROM AUTHOR]

Copyright of Railway Standard Design is the property of Railway Standard Design Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Most of the traditional indoor positioning technologies need to lay hardware equipment in advance, which is expensive and difficult to apply to part of the space where additional equipment cannot be laid. In order to reduce equipment cost as much as possible and reduce preparation work, this paper proposes an indoor positioning technology that integrates deep learning and feature point recognition. This technology uses mobile devices such as mobile phones to obtain realtime video streams, and uses a convolutional neural network-based marker recognizer to identify markers in each frame of the video stream, so as to obtain its rough position and complete rough positioning. At the same time, the feature points are identified for each frame of mage in the video stream, and matched with the feature points with location information in the constructed environment feature information database, and their positions are calculated to complete fine positioning. The technology proposed in this paper is based entirely on mage identification, without relying on the laying of hardware equipment, and can be better applied to secret spaces. This paper has completed the program deployment of the proposed indoor positioning technology on the Andriod mobile device terminal. The experiments show that the proposed indoor positioning technology has high accuracy and stability. [ABSTRACT FROM AUTHOR]

Objective To explore the correlation between geriatric depression and its related factors, and to reveal their impact on depression through bayesian reasoning, ao as to achieve prevention and treatment of depression. Methods Based on the China Health and Elderly Care Longitudinal Survey (CHARLS)2018, this study employed the Depression Scale of the Center for Epidemiology (CES-D) to conduct a questionnaire survey on the depression of the elderly population, and incorporates it into demographics, health status, lifestyle, etc. Afterwards, Elastic Net was used to conduct a preliminary screening of 12,468 participants. Last, we used Bayesian networks with MMHC algorithm was constructed, and parameter learning was achieved by maximum likelihood estimation. Results Among the 12,468 participants, 5,035 (40. 38% ) participants were subjected to depression. After feature screening using Elastic Net, 9 variables finally entered the model, which was constructed with 10 nodes and 14 directed edges. The model showed that education levels, sleep duration, instrumental activities of daily living (IADL), and self -- reported health were directly related to depression, suggesting that there were parent nodes of depression occurrence. Conclusion BNs can well reveal the complex network connection between depression and its related factors, enabling the identification of direct or indirect risk factors for depression in the elderly. Accordingly, prevention and control of depression occurrence can be made in a targeted manner in the elderly, which provides a reference for reducing the risk of depression and improving the quality of life of the elderly. [ABSTRACT FROM AUTHOR]

Objective To investigate the causal relationship between 211 intestinal flora and migraine using a two - sample Mendelian randomization method. Methods Independent genetic loci significantly associated with the relative abundance of 211 intestinal flora were extracted according to a predefined threshold using GWAS data for intestinal flora from the public database MiBioGen consortium study (n = 13 266) and GWAS data for migraine from the Finnish database ( The FinnGen Biobank) (n = 280 567 ) as instrumental variables (IVs) . Analyses were mainly performed using the inverse variance weighting method, and results were assessed according to the Odds ratio (OR) and 95% confidence interval (95% CI) of the effect indicators. The stability and reliability of the results were verified using the leave - one - out method, heterogeneity test, and horizontal genetic pleiotropy test. Results Elevated abundance of Bifidobacteriales, Bifidobacteriaceae, and Bifidobacterium reduced the risk of migraine with a dominance ratio and confidence interval of (OR = 0. 77, 95% CI :0. 70 - 0.83), (OR =0.77, 95% CI :0. 70 - 0. 83 ), and (OR =0.82, 95% CI :0. 74 -0.91), respectively. The leave - one - out analysis showed stable results, with no instrumental variables that had a strong effect on the results, and the effects of heterogeneity and horizontal genetic pleiotropy on the estimation of causal effects could be removed. Conclusion Bifidobacteriales, Bifidobacteriaceae, and Bifidobacterium are protective factors for the occurrence of migraine, and with increased abundance of flora able to reduce the onset of migraine and clinical medication, probiotics for migraine may become a future trend. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To explore and evaluate the safety signal of oseltamivir after the marketing, so as to provide basis for clinical rational drug use. METHODS: Adverse drug event (ADE) reports with oseltamivir as the first suspected drugs were retrieved from the Food and Drug Administration Adverse Event Reporting System ( FAERS) database from Jan. 2004 to Sept. 2022. Reporting Odds Ratio (ROR) method and Bayesian confidence propagation neural network ( BCPNN) method were sued to detect the ADE signals, mainly included 11 key system organ classification (SOC) such as gastrointestinal, neurological, psychiatric, and hepatobiliary systems. RESULTS: Totally 794 reports of ADE (794 patients) with oseltamivir as the first suspected drug were collected, with a higher proportion of female patients ( 394 cases, 49. 62%) than male patients ( 297 cases, 37. 41%). The reported ages were all concentrated under 18 years old ( 489 cases, 61. 59%), with 232 cases of SAE ( 29. 22%). The detected ADE signals involved a total of 21 SOC. Analysis of key SOC showed that the signals of neurological system-related ADE were mainly convulsive seizures (ROR = 2. 77, IC = 1. 43), loss of consciousness (ROR = 2. 01, IC = 0. 99), and speech disorders (ROR= 2. 67, IC = 1. 37). The main manifestations of psychiatric disorders were abnormal behavior (ROR= 30. 34, IC = 4. 74), hallucination (ROR = 20. 69, IC = 4. 22), insomnia (ROR = 2. 08, IC = 1. 03). The main manifestations of oseltamivir-related gastrointestinal tract were upper abdominal pain (ROR= 2. 05, IC = 1. 01), vomiting (ROR= 6. 19, IC = 2. 48) and hemorrhagic enterocolitis (ROR = 46. 35, IC = 4. 28). Other systemic highrisk signals were mainly hepatitis fulminant (ROR = 10. 88, IC = 2. 70), acute heart failure (ROR = 5. 89, IC = 2. 17), myocarditis (ROR= 4. 49, IC = 1. 93), disseminated intravascular coagulation (ROR = 2. 60, IC = 1. 25), Stevens-Johnson syndrome (ROR = 3. 44, IC = 1. 70), and toxic epidermal necrolysis (ROR = 2. 06, IC = 0. 94). CONCLUSIONS: During the use of oseltamivir, in addition to close attention to common ADE such as convulsive seizures, abnormal behavior, hallucinations, insomnia, vomiting and epigastric pain, SAE such as hepatitis fulminant, acute heart failure,and disseminated intravascular coagulation should be monitored. [ABSTRACT FROM AUTHOR]

In this paper， an ontology-based knowledge graph construction method for military terminology is proposed, which is used to obtain semantic information in military terminology corpus and construct military terminology knowledge graph. Then the ontology of military terminology is built firstly based on the analysis of military terminology corpus. In this method, the rule based method and the pre-trained model based method are used to extract the relation of military terminology and the knowledge of military terminology is stored in the graph database at last. This method can construct high quality knowledge graph of military terminology for intelligent applications such as semantic search， intelligent question and answer. [ABSTRACT FROM AUTHOR]

Aiming at the problem that LF ant colony clustering algorithm does not distinguish the importance of data set attributes, the algorithm efficiency is low and the clustering effect is unstable, this paper proposed a weighted global memory ant colony optimization (WGACO) based on entropy weight. Firstly, it calculated the entropy weight of each attribute by entropy weight method, and modified the Euclidean distance calculation formula to improve the clustering accuracy. It initialized the data object with the value of the largest weight attribute to enhance the stability of the clustering effect, and introduced the global memory matrix to reduce the invalid movement of ants and improve the efficiency of the algorithm. It added the convergence conditions of the algorithm to improve the practicability of the algorithm. Selecting seven real data sets and three artificially generated data sets in UCI database for numerical experiments, and compared WGACO with GMACO,SMACC and ILFACC three improved LF algorithms. The experimental results show that WGACO has a relatively good improvement in accuracy, algorithm efficiency and stability, and also has a good performance in processing high-dimensional data. Finally, WGACO has performed well in the segmentation of mall member users, reflecting its practical value. [ABSTRACT FROM AUTHOR]

The multifractal theory only performs statistical analysis on the singular exponents observed at any point on the geometric support of the fractal body. Multifractal correlation studies the spatial correlation characteristics between two points with different singular exponents. It is a generalization of single point statistics in multifractals. The two characteristics have a certain degree of complementarity. This paper investigated a method that combined the multifractal and its correlation features in the electrocardiogram（ECG） signal classification. Firstly, the method analyzed the multifractal and correlation characteristics of four types of ECG signals and obtained their respective features. Then it combined the probability distribution to select appropriate features for combination. The combined features fed into a support vector machine（SVM） for classification. This method tested on the MIT-BIH arrhythmia database and achieved an average accuracy of 97.90% after 20 training tests. Compared to independently using multifractal features, this method significantly improves the classification accuracy. [ABSTRACT FROM AUTHOR]

Copyright of South Architecture / Nanfang Jianzhu is the property of South Architecture Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To clarify the damage losses of invasive insects, the economic cost of global invasive insects were assessed in monetized form. InvaCost database was used to analyze all insecta data, and the conservative economic costs, expenditure costs, management and loss costs, and major invasive insect species from 1970 to 2017 were counted separately, based on which generalized least squares regression, robust regression, and quantile regression 3 models to predict the possible costs from 2010 to 2019. The results showed that the economic cost due to insect invasion from 1970 to 2017 was 500 438 million dollar, with an annual average of 10 426 million dollar. The United States had the highest spending cost in the world, and China ranked second about 50 352 million dollar (340 113 million yuan), and the economic cost of Aedes spp. was the highest among all invasive insect species. The model predicted a possible economic cost of 292.362~709.725 billion dollar in the 21st century 10s, with a maximum confidence value of 367.224 billion dollar. The assessment showed that the global economic costs of invasive insects over the past few decades had been enormous, but proactive management was clearly lacking. [ABSTRACT FROM AUTHOR]

Copyright of Journal of China Medical University is the property of Journal of China Medical University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of China Medical University is the property of Journal of China Medical University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to improve the efficiency and success rate of RV furniture manufacturing, the study of RV furniture CMF design database provided new design ideas and methods. Based on the CMF design theory, the analysis and interpretation of the design elements were carried out to assist the designer to better determine the design direction from the perspective of color, material and process, and to focus on the database structure and application of the RV furniture CMF design by establishing key technologies for the database strategy analysis. The effects of CMF design elements on product perceived quality, product aesthetics and emotional attributes, user needs and perception were obtained, and a caravan furniture database including CMF semantic library, theme style, business data and index data was constructed. The database included four levels of models, which provided accurate, reliable, clear and objective data support for the design of RV furniture, greatly shortened the design cycle of target furniture, improved the satisfaction rate of users and the actual production efficiency of the enterprise, from the direction of scientificity and feasibility. Meanwhile, this study provided applied strategies for database research and application. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Technology Economics is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Mine Automation is the property of Industry & Mine Automation Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Petroleum Geology & Oilfield Development in Daqing is the property of Editorial Department of Petroleum Geology & Oilfield Development in Daqing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Forensic Science & Technology is the property of Institute of Forensic Science, Ministry of Public Security and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Forensic Science & Technology is the property of Institute of Forensic Science, Ministry of Public Security and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mycosystema is the property of Mycosystema Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Petroleum Refinery Engineering is the property of Petroleum Refinery Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Machine Tool & Hydraulics is the property of Guangzhou Mechanical Engineering Research Institute (GMERI) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Mechanical Engineering is the property of Editorial Board of China Mechanical Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)